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This article examines the influence of literacy on the health of menopausetting (or pre-menopause) women in urban Calabar Metropolis of Cross River State, Nigeria. Two null hypotheses were formulated with a 45-item questionnaire from a representative sample size of 500 urban women between ages 35 and above, using purposive, stratified, and simple random sampling procedures. The research design is survey inferential, while data analysis was by one-way analysis of variance (ANOVA). Fisher's multiple comparison (LSD) and Independent t-test techniques were carried out. The analysis revealed that literacy level significantly influences the health of menopausetting women and that menopausetting women who are highly literate live healthier lives than their counterparts who are averagely and lowly literate. Some recommendations were made which will enhance longevity and ultimate well-being of menopausetting women. [ABSTRACT FROM AUTHOR]