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543 results on '"F., Zattoni"'

1. Towards epigenetic regulation of triple-negative breast cancer via ligand-mediated nanoparticles

Author

Guilherme F Picheth, Gabriela C Cardoso, Michelle B Collini, João OC Filizzola, Leonardo B Colauto, Giovana G Nunes, Cleverton L Pirich, Thiago Alessandre da Silva, Flávia LD Pontes, Ingrid F Zattoni, Edneia ASR Cavalieri, and Giseli Klassen

Subjects
Biomedical Engineering, Medicine (miscellaneous), General Materials Science, Bioengineering, Development
Abstract

Aims: Develop and analyze triple-negative breast cancer targeted nanoparticles loaded with the demethylating agent decitabine. Materials & methods: The polymers were synthesized by ring-opening polymerization of D,L-lactide and formulated into nanoparticles via emulsion-evaporation method. The nanoparticles were characterized by physicochemical analysis as well as in vitro using breast cancer cell lineages. Results & conclusion: The targeted nanoparticles exhibited a hydrodynamic diameter of 75 ± 12 nm, zeta potential -6.3 ± 0.2 mV and spherical morphology, and displayed greater in vitro accumulation into MDA-MB-231 (triple-negative breast cancer cell-line) compared with MCF7 and HB4A cell lineages as verified by fluorescence confocal microscopy and significant demethylating effects via ADAM33 screening by PCR.

Published
2023
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14. A systematic review of the efficacy and toxicity of brachytherapy boost combined with external beam radiotherapy for nonmetastatic prostate cancer

Author

Tilki, Derya, Slevin, F.; Zattoni, F.; Checcucci, E.; Cumberbatch, M.G.K.; Nacchia, A.; Cornford, P.; Briers, E.; De Meerleer, G.; De Santis, M.; Eberli, D.; Gandaglia, G.; Gillessen, S.; Grivas, N.; Liew, M.; Linares Espinós, E.E.; Oldenburg, J.; Oprea-Lager, D.E.; Ploussard, G.; Rouvière, O.; Schoots, I.G.; Smith, E.J.; Stranne, J.; Smith, C.T.; Van Den Bergh, R.C.N.; Van Oort, I.M.; Wiegel, T.; Yuan, C.Y.; Van den Broeck, T.; Henry, A.M., Koç University Hospital, School of Medicine, Tilki, Derya, Slevin, F.; Zattoni, F.; Checcucci, E.; Cumberbatch, M.G.K.; Nacchia, A.; Cornford, P.; Briers, E.; De Meerleer, G.; De Santis, M.; Eberli, D.; Gandaglia, G.; Gillessen, S.; Grivas, N.; Liew, M.; Linares Espinós, E.E.; Oldenburg, J.; Oprea-Lager, D.E.; Ploussard, G.; Rouvière, O.; Schoots, I.G.; Smith, E.J.; Stranne, J.; Smith, C.T.; Van Den Bergh, R.C.N.; Van Oort, I.M.; Wiegel, T.; Yuan, C.Y.; Van den Broeck, T.; Henry, A.M., Koç University Hospital, and School of Medicine

Abstract

Background Central nervous system (CNS) prophylactic options for diffuse large B-cell lymphoma (DLBCL) are administered differently in most centers. Unfortunately, there is still not a consensus on which patients, which regimen, for how many cycles, and when prophy-laxis should be administered. Thus, this remains an unmet clinical need. Methods We administered a survey study under the Lymphoma Scientific Subcommittee of the Turkish Society of Haematology. The questions were directed to hematologists through the monkey survey system. Results The CNS International Prognostic Index score is a factor that clinicians frequently use when deciding on prophylaxis and is considered reliable. Although the perspective on anatomical risk factors is similar to that reported in the literature, breast involvement is still considered a critical risk factor in Turkey. Participants considered double or triple hit and double/triple expressor lymphoma as significant risk factors. Various methods have been used to demonstrate CNS relapses. Intrathecal prophylaxis is the preferred method. Conclusion There are diverse methodological and technical ideas. The controversial results reported in the literature on the effectiveness of CNS prophylaxis may explain this finding. Although CNS prophylactic methods for patients with DLBCL are still controversial, the effect of secondary CNS involvement on survival is inevitable. Standard practices followed by na-tional guidelines may be effective in reducing the variety of application methods and creat-ing homogeneous results for efficacy and survival follow-up studies., NA

Published
2023

15. Can we rely on available models to identify candidates for extended Pelvic Lymph Node Dissection (ePLND) in men staged with PSMA-PET? External validation of the Briganti nomograms and development of a novel tool to identify optimal candidates for ePLND

Author

G. Gandaglia, D. Robesti, L. Bianchi, R. Schiavina, E. Brunocilla, L. Afferi, A. Mattei, F. Zattoni, P. Rajwa, S. Shariat, C. Kesch, J.M. Sierra, P. Gontero, G. Marra, H. Guo, J. Gomez Rivas, J. Zhuang, D. Amparore, F. Dal Moro, F. Porpiglia, C. Darr, W. Fendler, M. Picchio, F. Montorsi, and A. Briganti

Subjects
Urology, Medizin
Abstract

Weitere Verfasser:innen aus Einrichtungen außerhalb der Universität Duisburg-Essen sind nicht aufgeführt.

Published
2023

16. Il trattamento endourologico retrogrado della calcolosi cistinica multirecidivante: caso clinico paradigmatico

Author

P. Beltrami, A. Guttilla, L. Ruggera, and F. Zattoni

Subjects
Calcolosi cistinica, Trattamento endourologico retrogrado, Terapia medica, Internal medicine, RC31-1245, Diseases of the genitourinary system. Urology, RC870-923
Abstract

Presentiamo un caso clinico di calcolosi cistinica multirecidivante paradigmatico. Il paziente giungeva alla nostra osservazione dopo multipli trattamenti endourologici in altra sede con una situazione litiasica complessa: portatore di nefrostomie bilaterali e di stent ureterale destro venivano evidenziati calcoli multipli renali bilaterali e grosse calicificazioni ureterali, a destra a ridosso dello stent e a sinistra per un tratto di oltre 5 cm. Il trattamento endourologico retrogrado eseguito in più tempi, associato a una adeguata terapia medica per la cistinuria, ha portato a una bonifica completa. Riteniamo che il trattamento endourologico retrogrado rappresenti la modalità più adeguata per risolvere la calcolosi cistinica multirecidivante, al quale deve necessariamente essere associata la terapia farmacologica della cistinuria. Risulta altresi mandatario un trattamento in tempi brevi e una permanenza di eventuali endoprotesi ureterali per il tempo strettamente necessario, allo scopo di evitare calcificazioni degli stessi anche con formazioni litiasiche di ossalato di calcio. Ottenuta la bonifica, è consigliabile che anche i controlli vengano effettuati inizialmente secondo scadenze ravvicinate per poter risolvere eventuali recidive prima che raggiungano dimensioni tali da richiedere trattamenti più complessi.

Published
2018
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17. Il trattamento endourologico retrogrado nella calcolosi renale

Author

A. Iannetti, P. Beltrami, F. Zattoni, F. Gigli, and L. Ruggera

Subjects
Calcolosi, RIRS, Endourologia, Internal medicine, RC31-1245, Diseases of the genitourinary system. Urology, RC870-923
Abstract

Negli ultimi 30 anni la terapia della calcolosi urinaria ha subito notevoli modificazioni in virtù dello sviluppo di tecnologie che hanno reso possibile eseguire trattamenti sempre meno invasivi. Anche le linee guida sono cambiate di conseguenza e attualmente prevedono che la litotrissia extracorporea rappresenti la prima opzione terapeutica per calcoli renali inferiori ai 20 mm come la litotrissia percutanea lo sia per calcoli di dimensioni superiori. Nel nostro studio abbiamo valutato efficacia e sicurezza della litotrissia per via retrograda come prima linea di trattamento della calcolosi renale. In 35 pazienti sottoposti a trattamento endourologico retrogrado abbiamo ottenuto una bonifica completa con il primo trattamento nel 63% dei casi e nell'80% con un ritrattamento. Complicanze maggiori, risolte senza sequele, sono comparse in 3 pazienti. Differenze significative sono emerse solo nel confronto dei risultati per calcoli inferiori e superiori a 20 mm. Nella nostra esperienza la RIRS può rappresentare la prima scelta di trattamento in alternativa alle altre opzioni sia per calcoli di piccole che di grandi dimensioni in casi selezionati, soprattutto se si tratta di calcolosi recidivante.

Published
2018
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19. The prognostic impact of preoperative psma-pet on early oncological outcomes in prostate cancer patients treated with radical prostatectomy: Results of a multi-center analysis

Author

S.L.A. Scuderi, G. Gandaglia, E. Mazzone, N. Huebner, E. Brunocilla, F. Dal Moro, A. Sartorello, L. Ibanez, M-S. Jesús, A. Mattei, L. Afferi, S. Shariat, F. Wolfgang, M. Picchio, G. Marra, F. Zattoni, G. Reitano, P. Rajwa, J. Gomez-Rivas, C. Kesch, F. Porpiglia, D. Amparore, E. Checcucci, F. Montorsi, and A. Briganti

Subjects
Urology, Medizin
Abstract

Weitere Verfasser:innen aus Einrichtungen außerhalb der Universität Duisburg-Essen sind nicht aufgeführt.

Published
2023
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20. Impact of pre-operative PSMA PET/CT for men with cN0M0 conventional imaging and pN+ prostate cancer: Results from a multicenter study

Author

G. Marra, P. Rajwa, G. Montefusco, R.C.N. Van Den Bergh, F. Zattoni, F. Dal Moro, A. Magli, A. Affentranger, J.B. Grogg, T. Hermanns, B. Malkiewicz, K. Kowalczyk, S. Shariat, A. Bianchi, A. Antonelli, S. Gallina, W. Berchiche, X. Cathelineau, L. Afferi, C. Fankhauser, A. Mattei, S. Scuderi, A. Briganti, P. Gontero, and G. Gandaglia

Subjects
Urology
Published
2023
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21. Improving prediction of local stage by PSMA-PET: Development of a novel integrated tool for extracapsular extension and seminal vesicle invasion combining clinical and imaging features in localized prostate cancer

Author

S.L.A. Scuderi, G. Gandaglia, F. Barletta, L. Bianchi, F. Zattoni, F. Dal Moro, G. Reitano, P. Rajwa, N. Hübner, S. Shariat, C. Kesch, C. Darr, W. Fendler, J. Gomez-Rivas, J. Moreno-Sierra, G. Marra, H. Guo, J. Zhuang, D. Amparore, E. Checcucci, F. Porpiglia, R. Schiavina, E. Brunocilla, F. Montorsi, and A. Briganti

Subjects
Urology
Published
2023
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22. Unilateral pelvic lymph node dissection in prostate cancer patients diagnosed in the era of MRI-targeted biopsy: A study that challenges the dogma

Author

A. Martini, L. Wever, T.F.W. Soeterik, A. Rakauskas, C.D. Fankhauser, J.B. Grogg, E. Checcucci, G. Ploussard, P. Qiang, A. Affentranger, G. Marra, O. Ettala, F. Zattoni, U.G. Falagario, M. De Angelis, C. Kesch, M. Apfelbeck, T. Al-Hammouri, A. Kretschmer, V. Kasivisvanathan, F. Preisser, J. Olivier, J.P. Radtke, G. Carrieri, I. Jambor, P. Gontero, A. Briganti, P. Macek, P.K. Chiu, T. Hermanns, R.C. Van Den Bergh, G. Gandaglia, and M. Valerio

Subjects
Urology
Published
2022
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24. Prostate cancer detection rate of repeated biopsy in patients with positive mpMRI and negative initial target and random biopsy. An EAU-YAU Prostate Cancer Working Group multi-institutional study

Author

F. Zattoni, L.J.P. Pereira, J. Zhuang, J. Olivier, I. Puche-Sanz, P. Rajwa, G. La Bombarda, M. Maggi, A. Fuschi, A. Veccia, F. Ditonno, G. Marra, M. Valerio, V. Kasivisvanathan, A. Alessandro, F. Dal Moro, J.G. Rivas, R. Van Den Bergh, G. Gandaglia, and G. Novara

Subjects
Urology
Published
2023
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27. Docetaxel versus abiraterone acetate for metastatic hormone-sensitive prostate cancer: a real-life analysis

Author

Silvia Foti, Igor Tsaur, Anita Thomas, P. Ermacora, Guillaume Ploussard, Mona Kafka, Constance Thibault, Jarmo C B Hunting, Jasmin Bektic, Robert Dotzauer, G. Von Amsberg, Isabel Heidegger, Thomas Höfner, Maximilian P Brandt, F. Zattoni, Barak Rosenzweig, R.C.N. Van Den Bergh, Severin Rodler, Moran Gadot, E. Debedde, Derya Tilki, G. Gandaglia, Cristian Surcel, and A. Kretschmer

Subjects
Oncology, medicine.medical_specialty, chemistry.chemical_compound, Hormone sensitive prostate cancer, Docetaxel, chemistry, business.industry, Urology, Internal medicine, medicine, Abiraterone acetate, business, medicine.drug
Published
2021
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28. Radiation exposure during endoscopic procedures to treat urinary tract stones: impact of patients’ and stones’ characteristics

Author

F. Zattoni, A. Trianni, S. La Falce, F. Dal Moro, M. Sannino, G. De Giorgi, J. Collavino, Matteo Soligo, and S. Sekulovic

Subjects
Radiation exposure, medicine.medical_specialty, business.industry, Urology, Medicine, Urinary tract stones, Radiology, business, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282
Published
2020

29. Transperineal vs. transrectal MRI-targeted prostate biopsy: Evaluation of cancer detection risk and biopsy accuracy for clinical significant prostate cancer

Author

A. Morlacco, Veeru Kasivisvanathan, Giancarlo Marra, Matteo Soligo, Alessandro Marquis, G. Gandaglia, Junlong Zhuang, A. Kretschmer, Francesco Barletta, P. Gontero, M. Apfelbeck, F. Dal Moro, Hongqian Guo, Giuseppe Cirulli, and F. Zattoni

Subjects
medicine.medical_specialty, Prostate cancer, Prostate biopsy, medicine.diagnostic_test, business.industry, Urology, Biopsy, Medicine, Radiology, Cancer detection, business, medicine.disease
Published
2021
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30. An algorithm to personalize nerve sparing in men with unilateral high-risk prostate cancer

Author

A. Martini, T.F.W. Soeterik, H. Haverdings, R-G. Rahota, E. Checcucci, S. De Cillis, G.O. Cirulli, T. Hermanns, C.D. Fankhauser, L. Afferi, A. Mattei, C. Kesch, I. Heidegger, F. Preisser, F. Zattoni, A. Marquis, G. Marra, A. Briganti, F. Porpiglia, J.P. Van Basten, R.C.N. Van Den Bergh, H.H.E. Van Melick, G. Ploussard, G. Gandaglia, and M. Valerio

Subjects
Urology
Published
2021
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31. Has the COVID-19 outbreak changed the way we are treating prostate cancer? An EAU – YAU prostate cancer working group multi-institutional study

Author

G. Marra, F. Dal Moro, F. Zattoni, R.C.N. Van Den Bergh, Felix Preisser, F. Montorisi, Timo F.W. Soeterik, Jan Philipp Radtke, A. Briganti, Claudia Kesch, A. Morlacco, Francesco Barletta, N. Hoffmann, A. Kretschmer, and G. Gandaglia

Subjects
Oncology, medicine.medical_specialty, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), business.industry, Urology, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Outbreak, medicine.disease, Article, Prostate cancer, Internal medicine, medicine, business
Published
2021
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34. Comparison of learning curves with Da Vinci Standard/Si/Xi and single port robotic platform during radical prostatectomy: A single surgeon experience

Author

Hari T. Vigneswaran, Alessandro Veccia, F. Zattoni, Alessandro Antonelli, Claudio Simeone, Susan Talamini, Simone Francavilla, Simone Crivellaro, and F. Dal Moro

Subjects
medicine.medical_specialty, Computer science, Prostatectomy, Urology, General surgery, medicine.medical_treatment, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282, Single surgeon, Port (medical), Learning curve, medicine
Published
2020
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35. How to identify an 'easy' retrograde intra-renal surgery to be performed by naïve residents in defining a training program? ScorDiS Nomogram

Author

Paolo Beltrami, F. Dal Moro, G. Zecchini, Carlotta Zaborra, F. Zattoni, G. De Giorgi, and J. Collavino

Subjects
medicine.medical_specialty, business.industry, Urology, General surgery, Renal surgery, Medicine, Nomogram, business, Training program, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282
Published
2020

39. Multiparametric MRI before robot-assisted radical prostatectomy allows for a greater utilization of nerve sparing with no detrimental impact on surgical margins status

Author

Claudio Valotto, F. Dal Moro, F. Zattoni, Gianluca Giannarini, Rossano Girometti, Filippo Bonato, Stefano Pizzolitto, and Chiara Zuiani

Subjects
medicine.medical_specialty, Nerve sparing, business.industry, Prostatectomy, Urology, medicine.medical_treatment, Multiparametric MRI, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282, medicine, Radiology, business, Surgical Margins Status
Published
2020
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40. Radical prostatectomy in the robotic evolution: from da Vinci Standard to single port. a single surgeon outcomes comparison

Author

Rosa Autorino, Alessandro Antonelli, F. Dal Moro, F. Zattoni, H.T. Vignewaran, Simone Crivellaro, Simone Francavilla, Ryan W. Dobbs, Claudio Simeone, and Alessandro Veccia

Subjects
medicine.medical_specialty, Prostatectomy, business.industry, Urology, General surgery, medicine.medical_treatment, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282, Single surgeon, Port (medical), medicine, business
Published
2020
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41. The impact of multiparametric MRI on utilization of nerve sparing and surgical margins status in patients with clinically localized prostate cancer treated with robot-assisted radical prostatectomy

Author

F. Zattoni, Rossano Girometti, G. Giannarini, Claudio Valotto, Stefano Pizzolitto, and F. Dal Moro

Subjects
medicine.medical_specialty, Nerve sparing, business.industry, Prostatectomy, Urology, medicine.medical_treatment, Multiparametric MRI, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, lcsh:RC254-282, Prostate cancer, medicine, In patient, Radiology, business, Surgical Margins Status
Published
2020
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42. Added value of quantitative DCE imaging on mpMRI prediction of stage ≥pT3 prostate cancer

Author

Rossano Girometti, Claudio Valotto, G. Giannarini, F. Dal Moro, F. Zattoni, Carlotta Zaborra, Chiara Zuiani, and G. De Giorgi

Subjects
Oncology, medicine.medical_specialty, business.industry, Urology, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282, PT3 Prostate Cancer, Internal medicine, Added value, medicine, Stage (cooking), business
Published
2020
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43. Genomic subtypes of bladder cancer with distinct methylation profiles could be better identified by the Bladder EpiCheck test as compared to cystoscopy/urine cytology

Author

F. Zattoni, S. Zumerle, Mariangela Mancini, M. Saponaio, M. Montopoli, Marialaura Righetto, Francesco Pagano, F. Barcaro, and Eugenio Ragazzi

Subjects
medicine.medical_specialty, Bladder cancer, medicine.diagnostic_test, business.industry, Urology, Medicine, Methylation, Cystoscopy, business, medicine.disease, Urine cytology
Published
2019

47. Advance suburethral sling to treat male urinary incontinence: Evaluation of long-term functional outcomes in a large monocentric series

Author

F. Zattoni, L. Barbieri, F. Barcaro, L. Durante, M. Carlesso, A. Aceti, Arturo Calpista, Mariangela Mancini, M. Bisol, Matteo Soligo, and G. Aiello

Subjects
medicine.medical_specialty, business.industry, Urology, Suburethral Sling, medicine, Urinary incontinence, medicine.symptom, business, Term (time), Surgery
Published
2019
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48. Utility of mpMRI/transrectal US fusion confirmatory biopsy in men with a previous diagnosis of prostate cancer amenable to active surveillance

Author

Mariangela Mancini, Matteo Soligo, C. Lacognata, G. Costa, A. Lauro, G. La Bombarda, G. Novara, L. Durante, Nicola Zanovello, F. Zattoni, A. Morlacco, Marina Paola Gardiman, A. Aceti, and G. Zecchini

Subjects
medicine.medical_specialty, Prostate cancer, medicine.diagnostic_test, business.industry, Urology, Biopsy, Medicine, Radiology, business, medicine.disease
Published
2019
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