Author: "F. Hua" - Searchworks@Jio Institute Digital Library Search Results

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1,038 results on '"F. Hua"'

1. A WEIGHTED COHERENCE ESTIMATOR FOR COHERENT CHANGE DETECTION IN SYNTHETIC APERTURE RADAR IMAGES

Author: M. Wang, G. Huang, J. Zhang, F. Hua, and L. Lu
Subjects: Technology, Engineering (General). Civil engineering (General), TA1-2040, Applied optics. Photonics, TA1501-1820
Abstract: Synthetic aperture radar (SAR) coherent change detection (CCD) often utilizes the degree of coherence to detect changes that have occurred between two data collections. Although having shown some performances in change detection, many existing coherence estimators are still relatively limited because the change areas do not stand out well from all decorrelation areas due to the low cluster-to-noise ratio (CNR) and volume scattering. Moreover, many estimators require the equal-variance assumption between two SAR images of the same scene. However, the assumption is less likely to be met in regions of significant differences in intensity, such as the change areas. To address these problems, we proposed an improved coherence estimator that introduces the parameters about the true-variance ratio as the weights. Since these parameters are closely related to the ratio-change statistic in intensity-based change detection algorithms, their introduction frees the estimator from the need for the equal-variance assumption and enables detection results to largely combine the advantages of intensity-based and CCD methods. Experiments on simulated and real SAR image pairs demonstrate the effectiveness of the proposed estimator in highlighting the change, obviously improving the contrast between the change and the background.
Published: 2022
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2. MULTI-BASELINE INSAR ELEVATION INVERSION METHOD BASED ON THREE-DIMENSIONAL RECONSTRUCTION MODEL

Author: F. Hua, G. Peng, L. Lu, and Z. Wang
Subjects: Technology, Engineering (General). Civil engineering (General), TA1-2040, Applied optics. Photonics, TA1501-1820
Abstract: The existing multi-baseline methods have some problems of low accuracy and intensive calculation. In order to solve the problems, a new multi-baseline InSAR elevation inversion method based on a rigorous geometric model instead of a simplified model is proposed in the letter. This method introduces the three-dimensional reconstruction model based on rigorous geometric model and the unknown full cycles of interferometric phase as a parameter to iteratively solve the 3-D coordinates of the target. With adopting the 3-D coordinate information of targets to connect different interferometric data, the new method obviously weakens the effects of system errors on solving the integer cycle and is more reliable than conventional multi-baseline InSAR methods. The experimental results show that the speed and accuracy of the new method are better than the existing methods.
Published: 2017
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3. RESEARCH OF MULTI-BASELINE INSAR ELEVATION INVERSION BASED ON MLHE METHOD

Author: F. Hua, J. Zhang, and G. Hunag
Subjects: Technology, Engineering (General). Civil engineering (General), TA1-2040, Applied optics. Photonics, TA1501-1820
Abstract: In this paper, we studied on Maximum Likelihood Height Estimate (MLHE) method to invert elevation using Multi-Baseline InSAR (MB-InSAR) Data. Then a set of simulated data were adopted to do the experiment to illustrate its availability. Meanwhile, this paper also presents the advantages and disadvantages of this approach with analysis of the influence of phase, baseline and range error on elevation inversion, as well as the following attention.
Published: 2013
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4. Spatial separation of prey from livestock facilitates coexistence of a specialized large carnivore with human land use

Author: L Xiao, F Hua, J M H Knops, X Zhao, C Mishra, S Lovari, J S Alexander, B Weckworth, and Z Lu
Subjects: Ecology, Nature and Landscape Conservation
Published: 2022
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5. PL study of Mn-doped ZnO nanowires

Author: null F. Hua, null P. Jong, and null D. Shuan
Abstract: Mn-doped ZnO nanowires have been fabricated through a high temperature vapor-solid deposition process. The low-temperature photoluminescence spectra of the samples show that there are multipeak emissions at the ultra- violet (UV) region (about 3.4–3.0 eV). The excitonic and phonon-assisted transitions in Mn-doped ZnO nanowires were investigated. The results show that there is an obvious oscillatory structure emission at the UV region under low temperature from 12–125 K. The oscillatory structure has an energy periodicity about 70 meV and the oscillatory structure is mainly attributed to longitudinal optical (LO) phonon replicas of free excitons (FX). The multipeak emissions at 12 K are attributed to a donor-bound exciton (DBX, 3.3617 eV), 1LO-phonon replicas of a free exciton (FX- 1LO, 3.3105 eV), 2LO-phonon replicas of a free exciton (FX-2LO, 3.2396 eV), and 3LO-phonon replicas of a free exciton (FX-3LO, 3.1692 eV), respectively. The intensity of UV emission and the efficiency of emission from the Mn- doped ZnO nanowires are improved.
Published: 2022
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6. [Impact of regional positive lymph node ratio of gallbladder carcinoma on prognosis]

Author: Y M, Zhou, H C, Mi, W, Jiang, Y, Jiang, Y F, Hua, C J, Lu, C N, Wang, and C D, Lu
Subjects: Lymphatic Metastasis, Humans, Lymph Node Excision, Gallbladder Neoplasms, Lymph Nodes, Prognosis, Lymph Node Ratio, Neoplasm Staging, Retrospective Studies
Published: 2022

7. [Percentage of tonsil hypertrophy in orthodontic patients with different sagittal skeletal relationship]

Author: T T, Zhao, M, Wang, Z, Yang, J, Zhang, F, Hua, and H, He
Subjects: Adult, Adolescent, Cephalometry, Palatine Tonsil, Humans, Hypertrophy, Child, Malocclusion, Retrospective Studies
Published: 2022

8. [Effect factors of collateral blood supply of patients with early trimester cesarean scar pregnancy]

Author: W, Zhang, G, Li, C F, Hua, H B, Wang, T Q, Zhang, Q L, Chen, H, Liang, and B H, Liu
Subjects: Adult, Cicatrix, Treatment Outcome, Double-Blind Method, Cesarean Section, Pregnancy, Case-Control Studies, Humans, Female, Retrospective Studies
Published: 2022

9. [Comparison of early outcome between one-stage hybrid technique and frozen elephant thunk technique in the treatment of Stanford A aortic dissection involving the arch]

Author: Y H, Chen, Z Y, Shen, H Y, Huang, Y S, Yu, W X, Ye, F, Hua, Y Q, Hu, B W, Yang, and H, Shen
Subjects: Male, Aortic Dissection, Blood Vessel Prosthesis Implantation, Treatment Outcome, Aortic Aneurysm, Thoracic, Humans, Aorta, Thoracic, Female, Retrospective Studies
Published: 2021

10. [Concomitant medullary and papillary thyroid carcinoma identified by fine needle aspiration: report of a case]

Author: F, Hua, L, Jin, X L, Zhou, and Y Q, Cheng
Subjects: Thyroid Cancer, Papillary, Biopsy, Fine-Needle, Humans, Thyroid Neoplasms, Carcinoma, Papillary
Abstract: 分析1例同侧甲状腺髓样癌合并乳头状癌的病例。观察肿瘤的细胞学形态及术后组织病理形态特点，讨论甲状腺髓样癌合并乳头状癌的细胞学诊断及鉴别诊断要点。.
Published: 2021

11. Dynamic modeling and performance analysis of the 2PRU-PUU parallel mechanism

Author: T. Sun, W. Ye, C. Yang, and F. Huang
Subjects: Materials of engineering and construction. Mechanics of materials, TA401-492
Abstract: This paper investigates the dynamic modeling and performance analysis of the 2PRU-PUU reconfigurable parallel mechanism (RPM); here, P, R, and U denote the prismatic, revolute, and universal joints, respectively. By altering one of the rotation axes of the reconfigurable universal joint in limb 3, the mechanism can be switched into two operation modes, 1R2T and 2R1T. The authors resort to the Lagrangian equations of the first kind to derive the dynamic model of the 2PRU-PUU RPM. The optimal driving force distribution is determined to solve the problem of the non-uniqueness solution in dynamic analysis. The dynamic formulations are verified with the results obtained in ADAMS software. The dynamic manipulability ellipsoid index, which offers a quantitative assessment of the ability in manipulating the end effector, is used to assess the dynamic performance of the mechanism. Then, the distribution characteristics of the rotational and translational dynamic performance of the RPM are derived.
Published: 2024
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12. [Diagnostic value of FNDC5 in patients with subclinical diabetic cardiomyopathy]

Author: Z H, Qin, X L, Huang, L C, Tao, and F, Hua
Published: 2021

13. Spin in the Abstracts of Randomized Controlled Trials in Operative Dentistry: A Cross-sectional Analysis

Author: X Fang, X Wu, C Levey, Z Chen, F Hua, and L Zhang
Subjects: General Dentistry
Abstract: SUMMARY Objective To assess the presence and characteristics of spin in recently published RCT abstracts in operative dentistry and to investigate potential factors associated with the presence of spin. Methods and Materials The PubMed database was searched to identify parallel-group RCTs published between 2015 and 2019 in the field of operative dentistry, which compared two or more groups and had nonsignificant results for the primary outcome. Two authors evaluated independently the presence and characteristics of spin among these abstracts. Multivariable logistic regression analyses were conducted to identify factors associated with the presence of spin in the Results and the Conclusions sections, respectively. Results A total of 77 RCT abstracts were included, among which 58 (75.3%) showed at least one type of spin. Spin was identified in the Results and Conclusions sections of 32 (41.6%) and 45 (58.4%) abstracts, respectively. 19 RCTs (24.7%) presented spin in both the Results and the Conclusions section of abstracts. The presence of spin in the Results section of abstracts was significantly associated with source of funding (OR=8.10; p=0.025) and number of treatment arms was associated with the presence of spin in the Conclusions section of abstracts (OR=5.66; p=0.005). Conclusion The occurrence rate of spin in the sample of operative dentistry RCTs abstracts is high.
Published: 2021

14. [Evaluations of total hilar en bloc resection and reconstruction in comparison with portal vein resection and reconstruction in treatment of perihilar cholangiocarcinoma]

Author: C D, Lu, J, Huang, S D, Wu, J Z, Fang, Y F, Hua, C J, Lu, G Q, Wang, and Y Y, Shan
Subjects: Male, Portal Vein, Middle Aged, Plastic Surgery Procedures, Cholangiocarcinoma, Biliary Tract Surgical Procedures, Bile Ducts, Intrahepatic, Hepatic Artery, Treatment Outcome, Bile Duct Neoplasms, Feasibility Studies, Hepatectomy, Humans, Female, Vascular Surgical Procedures, Aged, Klatskin Tumor, Retrospective Studies
Published: 2021

15. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Author: D. KLIONSKY, A. ABDEL-AZIZ, S. ABDELFATAH, M. ABDELLATIF, A. ABDOLI, S. ABEL, H. ABELIOVICH, M. ABILDGAARD, Y. ABUDU, A. ACEVEDO-AROZENA, I. ADAMOPOULOS, K. ADELI, T. ADOLPH, A. ADORNETTO, E. AFLAKI, G. AGAM, A. AGARWAL, B. AGGARWAL, M. AGNELLO, P. AGOSTINIS, J. AGREWALA, A. AGROTIS, P. AGUILAR, S. AHMAD, Z. AHMED, U. AHUMADA-CASTRO, S. AITS, S. AIZAWA, Y. AKKOC, T. AKOUMIANAKI, H. AKPINAR, A. AL-ABD, L. AL-AKRA, A. AL-GHARAIBEH, M. ALAOUI-JAMALI, S. ALBERTI, E. ALCOCER-GOMEZ, C. ALESSANDRI, M. ALI, M. AL-BARI, S. ALIWAINI, J. ALIZADEH, E. ALMACELLAS, A. ALMASAN, A. ALONSO, G. ALONSO, N. ALTAN-BONNET, D. ALTIERI, S. ALVES, C. DA COSTA, M. ALZAHARNA, M. AMADIO, C. AMANTINI, C. AMARAL, S. AMBROSIO, A. AMER, V. AMMANATHAN, Z. AN, S. ANDERSEN, S. ANDRABI, M. ANDRADE-SILVA, A. ANDRES, S. ANGELINI, D. ANN, U. ANOZIE, M. ANSARI, P. ANTAS, A. ANTEBI, Z. ANTON, T. ANWAR, L. APETOH, N. APOSTOLOVA, T. ARAKI, Y. ARAKI, K. ARASAKI, W. ARAUJO, J. ARAYA, C. ARDEN, M. AREVALO, S. ARGUELLES, E. ARIAS, J. ARIKKATH, H. ARIMOTO, A. ARIOSA, D. ARMSTRONG-JAMES, L. ARNAUNE-PELLOQUIN, A. AROCA, D. ARROYO, I. ARSOV, R. ARTERO, D. ASARO, M. ASCHNER, M. ASHRAFIZADEH, O. ASHUR-FABIAN, A. ATANASOV, A. AU, P. AUBERGER, H. AUNER, L. AURELIAN, R. AUTELLI, L. AVAGLIANO, Y. AVALOS, S. AVEIC, C. AVELEIRA, T. AVINWITTENBERG, Y. AYDIN, S. AYTON, S. AYYADEVARA, M. AZZOPARDI, M. BABA, J. BACKER, S. BACKUES, D. BAE, O. BAE, S. BAE, E. BAEHRECKE, A. BAEK, S. BAEK, G. BAGETTA, A. BAGNIEWSKA-ZADWORNA, H. BAI, J. BAI, X. BAI, Y. BAI, N. BAIRAGI, S. BAKSI, T. BALBI, C. BALDARI, W. BALDUINI, A. BALLABIO, M. BALLESTER, S. BALAZADEH, R. BALZAN, R. BANDOPADHYAY, S. BANERJEE, Y. BAO, M. BAPTISTA, A. BARACCA, C. BARBATI, A. BARGIELA, D. BARILA, P. BARLOW, S. BARMADA, E. BARREIRO, G. BARRETO, J. BARTEK, B. BARTEL, A. BARTOLOME, G. BARVE, S. BASAGOUDANAVAR, D. BASSHAM, R. JR, A. BASU, H. BATOKO, I. BATTEN, E. BAULIEU, B. BAUMGARNER, J. BAYRY, R. BEALE, I. BEAU, F. BEAUMATIN, L. BECHARA, G. BECK, M. BEERS, J. BEGUN, C. BEHRENDS, G. BEHRENS, R. BEI, E. BEJARANO, S. BEL, C. BEHL, A. BELAID, N. BELGAREH-TOUZE, C. BELLAROSA, F. BELLEUDI, M. PEREZ, R. BELLO-MORALES, J. BELTRAN, S. BELTRAN, D. BENBROOK, M. BENDORIUS, B. BENITEZ, I. BENITO-CUESTA, J. BENSALEM, M. BERCHTOLD, S. BEREZOWSKA, D. BERGAMASCHI, M. BERGAMI, A. BERGMANN, L. BERLIOCCHI, C. BERLIOZ-TORRENT, A. BERNARD, L. BERTHOUX, C. BESIRLI, S. BESTEIRO, V. BETIN, R. BEYAERT, J. BEZBRADICA, K. BHASKAR, I. BHATIA-KISSOVA, R. BHATTACHARYA, S. BHATTACHARYA, S. BHATTACHARYYA, M. BHUIYAN, S. BHUTIA, L. BI, X. BI, T. BIDEN, K. BIJIAN, V. BILLES, N. BINART, C. BINCOLETTO, A. BIRGISDOTTIR, G. BJORKOY, G. BLANCO, A. BLAS-GARCIA, J. BLASIAK, R. BLOMGRAN, K. BLOMGREN, J. BLUM, E. BOADA-ROMERO, M. BOBAN, K. BOESZEBATTAGLIA, P. BOEUF, B. BOLAND, P. BOMONT, P. BONALDO, S. BONAM, L. BONFILI, J. BONIFACINO, B. BOONE, M. BOOTMAN, M. BORDI, C. BORNER, B. BORNHAUSER, G. BORTHAKUR, J. BOSCH, S. BOSE, L. BOTANA, J. BOTAS, C. BOULANGER, M. BOULTON, M. BOURDENX, B. BOURGEOIS, N. BOURKE, G. BOUSQUET, P. BOYA, P. BOZHKOV, L. BOZI, T. BOZKURT, D. BRACKNEY, C. BRANDTS, R. BRAUN, G. BRAUS, R. BRAVO-SAGUA, J. BRAVO-SAN PEDRO, P. BREST, M. BRINGER, A. BRIONES-HERRERA, V. BROADDUS, P. BRODERSEN, E. ALVAREZ, J. BRODSKY, S. BRODY, P. BRONSON, J. BRONSTEIN, C. BROWN, R. BROWN, P. BRUM, J. BRUMELL, N. BRUNETTI-PIERRI, D. BRUNO, R. BRYSON-RICHARDSON, C. BUCCI, C. BUCHRIESER, M. BUENO, L. BUITRAGO-MOLINA, S. BURASCHI, S. BUCH, J. BUCHAN, E. BUCKINGHAM, H. BUDAK, M. BUDINI, G. BULTYNCK, F. BURADA, J. BURGOYNE, M. BURON, V. BUSTOS, S. BUTTNER, E. BUTTURINI, A. BYRD, I. CABAS, S. CABRERA-BENITEZ, K. CADWELL, J. CAI, L. CAI, Q. CAI, M. CAIRO, J. CALBET, G. CALDWELL, K. CALDWELL, J. CALL, R. CALVANI, A. CALVO, M. BARRERA, N. CAMARA, J. CAMONIS, N. CAMOUGRAND, M. CAMPANELLA, E. CAMPBELL, F. CAMPBELL-VALOIS, S. CAMPELLO, I. CAMPESI, J. CAMPOS, O. CAMUZARD, J. CANCINO, D. DE ALMEIDA, L. CANESI, I. CANIGGIA, B. CANONICO, C. CANTI, B. CAO, M. CARAGLIA, B. CARAMES, E. CARCHMAN, E. CARDENAL-MUNOZ, C. CARDENAS, L. CARDENAS, S. CARDOSO, J. CAREW, G. CARLE, G. CARLETON, S. CARLONI, D. CARMONA-GUTIERREZ, L. CARNEIRO, O. CARNEVALI, J. CAROSI, S. CARRA, A. CARRIER, L. CARRIER, B. CARROLL, A. CARTER, A. CARVALHO, M. CASANOVA, C. CASAS, J. CASAS, C. CASSIOLI, E. CASTILLO, K. CASTILLO, S. CASTILLO-LLUVA, F. CASTOLDI, M. CASTORI, A. CASTRO, M. CASTRO-CALDAS, J. CASTRO-HERNANDEZ, S. CASTRO-OBREGON, S. CATZ, C. CAVADAS, F. CAVALIERE, G. CAVALLINI, M. CAVINATO, M. CAYUELA, P. RICA, V. CECARINI, F. CECCONI, M. CECHOWSKA-PASKO, S. CENCI, V. CEPERUELO-MALLAFRE, J. CERQUEIRA, J. CERUTTI, D. CERVIA, V. CETINTAS, S. CETRULLO, H. CHAE, A. CHAGIN, C. CHAI, G. CHAKRABARTI, O. CHAKRABARTI, T. CHAKRABORTY, M. CHAMI, G. CHAMILOS, D. CHAN, E. CHAN, H. CHAN, M. CHAN, Y. CHAN, P. CHANDRA, C. CHANG, H. CHANG, K. CHANG, J. CHAO, T. CHAPMAN, N. CHARLET-BERGUERAND, S. CHATTERJEE, S. CHAUBE, A. CHAUDHARY, S. CHAUHAN, E. CHAUM, F. CHECLER, M. CHEETHAM, C. CHEN, G. CHEN, J. CHEN, L. CHEN, M. CHEN, N. CHEN, Q. CHEN, R. CHEN, S. CHEN, W. CHEN, X. CHEN, Y. CHEN, Z. CHEN, H. CHENG, J. CHENG, S. CHENG, W. CHENG, X. CHENG, Y. CHENG, Z. CHENG, H. CHEONG, J. CHEONG, B. CHERNYAK, S. CHERRY, C. CHEUNG, K. CHEUNG, E. CHEVET, R. CHI, A. CHIANG, F. CHIARADONNA, R. CHIARELLI, M. CHIARIELLO, N. CHICA, S. CHIOCCA, M. CHIONG, S. CHIOU, A. CHIRAMEL, V. CHIURCHIU, D. CHO, S. CHOE, A. CHOI, M. CHOI, K. CHOUDHURY, N. CHOW, C. CHU, J. CHUA, H. CHUNG, K. CHUNG, S. CHUNG, Y. CHUNG, V. CIANFANELLI, I. CIECHOMSKA, M. CIFUENTES, L. CINQUE, S. CIRAK, M. CIRONE, M. CLAGUE, R. CLARKE, E. CLEMENTI, E. COCCIA, P. CODOGNO, E. COHEN, M. COHEN, T. COLASANTI, F. COLASUONNO, R. COLBERT, A. COLELL, N. COLL, M. COLLINS, M. COLOMBO, D. COLON-RAMOS, L. COMBARET, S. COMINCINI, M. COMINETTI, A. CONSIGLIO, A. CONTE, F. CONTI, V. CONTU, M. COOKSON, K. COOMBS, I. COPPENS, M. CORASANITI, D. CORKERY, N. CORDES, K. CORTESE, M. COSTA, S. COSTANTINO, P. COSTELLI, A. COTO-MONTES, P. CRACK, J. CRESPO, A. CRIOLLO, V. CRIPPA, R. CRISTOFANI, T. CSIZMADIA, A. CUADRADO, B. CUI, J. CUI, Y. CUI, E. CULETTO, A. CUMINO, A. CYBULSKY, M. CZAJA, S. CZUCZWAR, S. D'ADAMO, M. D'AMELIO, D. D'ARCANGELO, A. D'LUGOS, G. D'ORAZI, J. DA SILVA, H. DAFSARI, R. DAGDA, Y. DAGDAS, M. DAGLIA, X. DAI, Y. DAI, J. DAL COL, P. DALHAIMER, L. DALLA VALLE, T. DALLENGA, G. DALMASSO, M. DAMME, I. DANDO, N. DANTUMA, A. DARLING, H. DAS, S. DASARATHY, S. DASARI, S. DASH, O. DAUMKE, A. DAUPHINEE, J. DAVIES, V. DAVILA, R. DAVIS, T. DAVIS, S. NAIDU, F. DE AMICIS, K. DE BOSSCHER, F. DE FELICE, L. DE FRANCESCHI, C. DE LEONIBUS, M. BARBOSA, G. DE MEYER, A. DE MILITO, C. DE NUNZIO, C. DE PALMA, M. DE SANTI, C. DE VIRGILIO, D. DE ZIO, J. DEBNATH, B. DEBOSCH, J. DECUYPERE, M. DEEHAN, G. DEFLORIAN, J. DEGREGORI, B. DEHAY, G. DEL RIO, J. DELANEY, L. DELBRIDGE, E. DELORME-AXFORD, M. DELPINO, F. DEMARCHI, V. DEMBITZ, N. DEMERS, H. DENG, Z. DENG, J. DENGJEL, P. DENT, D. DENTON, M. DEPAMPHILIS, C. DER, V. DERETIC, A. 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ELEUTERI, E. EL-SHAFEY, M. ELGENDY, A. ELIOPOULOS, M. ELIZALDE, P. ELKS, H. ELSASSER, E. ELSHERBINY, B. EMERLING, N. EMRE, C. ENG, N. ENGEDAL, A. ENGELBRECHT, A. ENGELSEN, J. ENSERINK, R. ESCALANTE, A. ESCLATINE, M. ESCOBAR-HENRIQUES, E. ESKELINEN, L. ESPERT, M. EUSEBIO, G. FABRIAS, C. FABRIZI, A. FACCHIANO, F. FACCHIANO, B. FADEEL, C. FADER, A. FAESEN, W. FAIRLIE, A. FALCO, B. FALKENBURGER, D. FAN, J. FAN, Y. FAN, E. FANG, Y. FANG, M. FANTO, T. FARFEL-BECKER, M. FAURE, G. FAZELI, A. FEDELE, A. FELDMAN, D. FENG, J. FENG, L. FENG, Y. FENG, W. FENG, T. ARAUJO, T. FERGUSON, J. FERNANDEZ-CHECA, S. FERNANDEZVELEDO, A. FERNIE, A. FERRANTE, A. FERRARESI, M. FERRARI, J. FERREIRA, S. FERRO-NOVICK, A. FIGUERAS, R. FILADI, N. FILIGHEDDU, E. FILIPPICHIELA, G. FILOMENI, G. FIMIA, V. FINESCHI, F. FINETTI, S. FINKBEINER, E. FISHER, P. FISHER, F. FLAMIGNI, S. FLIESLER, T. FLO, I. FLORANCE, O. FLOREY, T. FLORIO, E. FODOR, C. FOLLO, E. FON, A. FORLINO, F. FORNAI, P. FORTINI, A. FRACASSI, A. FRALDI, B. 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ZHANG, W. ZHANG, X. ZHANG, Y. ZHANG, Z. ZHANG, H. ZHAO, L. ZHAO, S. ZHAO, T. ZHAO, X. ZHAO, Y. ZHAO, G. ZHENG, K. ZHENG, L. ZHENG, S. ZHENG, X. ZHENG, Y. ZHENG, Z. ZHENG, B. ZHIVOTOVSKY, Q. ZHONG, A. ZHOU, B. ZHOU, C. ZHOU, G. ZHOU, H. ZHOU, J. ZHOU, K. ZHOU, R. ZHOU, X. ZHOU, Y. ZHOU, Z. ZHOU, B. ZHU, C. ZHU, G. ZHU, H. ZHU, W. ZHU, Y. ZHU, H. ZHUANG, X. ZHUANG, K. ZIENTARA-RYTTER, C. ZIMMERMANN, E. ZIVIANI, T. ZOLADEK, W. ZONG, D. ZOROV, A. ZORZANO, W. ZOU, Z. ZOU, S. ZURYN, W. ZWERSCHKE, B. BRAND-SABERI, C. KENCHAPPA, S. OSHIMA, Y. RONG, J. SLUIMER, and C. STALLINGS
Subjects: flux, macroautophagy, phagophore, stress, vacuole, Autophagosome, LC3, lysosome, neurodegeneration, cancer
Abstract: In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field.
Published: 2021

16. sPlotOpen:an environmentally balanced, open-access, global dataset of vegetation plots

Author: Sabatini, F. M. (Francesco Maria), Lenoir, J. (Jonathan), Hattab, T. (Tarek), Arnst, E. A. (Elise Aimee), Chytry, M. (Milan), Dengler, J. (Juergen), De Ruffray, P. (Patrice), Hennekens, S. M. (Stephan M.), Jandt, U. (Ute), Jansen, F. (Florian), Jimenez-Alfaro, B. (Borja), Kattge, J. (Jens), Levesley, A. (Aurora), Pillar, V. D. (Valerio D.), Purschke, O. (Oliver), Sandel, B. (Brody), Sultana, F. (Fahmida), Aavik, T. (Tsipe), Acic, S. (Svetlana), Acosta, A. T. (Alicia T. R.), Agrillo, E. (Emiliano), Alvarez, M. (Miguel), Apostolova, I. (Iva), Arfin Khan, M. A. (Mohammed A. S.), Arroyo, L. (Luzmila), Attorre, F. (Fabio), Aubin, I. (Isabelle), Banerjee, A. (Arindam), Bauters, M. (Marijn), Bergeron, Y. (Yves), Bergmeier, E. (Erwin), Biurrun, I. (Idoia), Bjorkman, A. D. (Anne D.), Bonari, G. (Gianmaria), Bondareva, V. (Viktoria), Brunet, J. (Jorg), Carni, A. (Andraz), Casella, L. (Laura), Cayuela, L. (Luis), Cerny, T. (Tomas), Chepinoga, V. (Victor), Csiky, J. (Janos), Custerevska, R. (Renata), De Bie, E. (Els), de Gasper, A. L. (Andre Luis), De Sanctis, M. (Michele), Dimopoulos, P. (Panayotis), Dolezal, J. (Jiri), Dziuba, T. (Tetiana), El-Sheikh, M. A. (Mohamed Abd El-Rouf Mousa), Enquist, B. (Brian), Ewald, J. (Joerg), Fazayeli, F. (Farideh), Field, R. (Richard), Finckh, M. (Manfred), Gachet, S. (Sophie), Galan-de-Mera, A. (Antonio), Garbolino, E. (Emmanuel), Gholizadeh, H. (Hamid), Giorgis, M. (Melisa), Golub, V. (Valentin), Alsos, I. G. (Inger Greve), Grytnes, J.-A. (John-Arvid), Guerin, G. R. (Gregory Richard), Gutierrez, A. G. (Alvaro G.), Haider, S. (Sylvia), Hatim, M. Z. (Mohamed Z.), Herault, B. (Bruno), Hinojos Mendoza, G. (Guillermo), Hoelzel, N. (Norbert), Homeier, J. (Juergen), Hubau, W. (Wannes), Indreica, A. (Adrian), Janssen, J. A. (John A. M.), Jedrzejek, B. (Birgit), Jentsch, A. (Anke), Juergens, N. (Norbert), Kacki, Z. (Zygmunt), Kapfer, J. (Jutta), Karger, D. N. (Dirk Nikolaus), Kavgaci, A. (Ali), Kearsley, E. (Elizabeth), Kessler, M. (Michael), Khanina, L. (Larisa), Killeen, T. (Timothy), Korolyuk, A. (Andrey), Kreft, H. (Holger), Kuehl, H. S. (Hjalmar S.), Kuzemko, A. (Anna), Landucci, F. (Flavia), Lengyel, A. (Attila), Lens, F. (Frederic), Lingner, D. V. (Debora Vanessa), Liu, H. (Hongyan), Lysenko, T. (Tatiana), Mahecha, M. D. (Miguel D.), Marceno, C. (Corrado), Martynenko, V. (Vasiliy), Moeslund, J. E. (Jesper Erenskjold), Monteagudo Mendoza, A. (Abel), Mucina, L. (Ladislav), Muller, J. V. (Jonas V.), Munzinger, J. (Jerome), Naqinezhad, A. (Alireza), Noroozi, J. (Jalil), Nowak, A. (Arkadiusz), Onyshchenko, V. (Viktor), Overbeck, G. E. (Gerhard E.), Partel, M. (Meelis), Pauchard, A. (Anibal), Peet, R. K. (Robert K.), Penuelas, J. (Josep), Perez-Haase, A. (Aaron), Peterka, T. (Tomas), Petrik, P. (Petr), Peyre, G. (Gwendolyn), Phillips, O. L. (Oliver L.), Prokhorov, V. (Vadim), Rasomavicius, V. (Valerijus), Revermann, R. (Rasmus), Rivas-Torres, G. (Gonzalo), Rodwell, J. S. (John S.), Ruprecht, E. (Eszter), Rusina, S. (Solvita), Samimi, C. (Cyrus), Schmidt, M. (Marco), Schrodt, F. (Franziska), Shan, H. (Hanhuai), Shirokikh, P. (Pavel), Sibik, J. (Jozef), Silc, U. (Urban), Sklenar, P. (Petr), Skvorc, Z. (Zeljko), Sparrow, B. (Ben), Sperandii, M. G. (Marta Gaia), Stancic, Z. (Zvjezdana), Svenning, J.-C. (Jens-Christian), Tang, Z. (Zhiyao), Tang, C. Q. (Cindy Q.), Tsiripidis, I. (Ioannis), Vanselow, K. A. (Kim Andre), Vasquez Martinez, R. (Rodolfo), Vassilev, K. (Kiril), Velez-Martin, E. (Eduardo), Venanzoni, R. (Roberto), Vibrans, A. C. (Alexander Christian), Violle, C. (Cyrille), Virtanen, R. (Risto), von Wehrden, H. (Henrik), Wagner, V. (Viktoria), Walker, D. A. (Donald A.), Waller, D. M. (Donald M.), Wang, H.-F. (Hua-Feng), Wesche, K. (Karsten), Whitfeld, T. J. (Timothy J. S.), Willner, W. (Wolfgang), Wiser, S. K. (Susan K.), Wohlgemuth, T. (Thomas), Yamalov, S. (Sergey), Zobel, M. (Martin), Bruelheide, H. (Helge), Sabatini, F. M. (Francesco Maria), Lenoir, J. (Jonathan), Hattab, T. (Tarek), Arnst, E. A. (Elise Aimee), Chytry, M. (Milan), Dengler, J. (Juergen), De Ruffray, P. (Patrice), Hennekens, S. M. (Stephan M.), Jandt, U. (Ute), Jansen, F. (Florian), Jimenez-Alfaro, B. (Borja), Kattge, J. (Jens), Levesley, A. (Aurora), Pillar, V. D. (Valerio D.), Purschke, O. (Oliver), Sandel, B. (Brody), Sultana, F. (Fahmida), Aavik, T. (Tsipe), Acic, S. (Svetlana), Acosta, A. T. (Alicia T. R.), Agrillo, E. (Emiliano), Alvarez, M. (Miguel), Apostolova, I. (Iva), Arfin Khan, M. A. (Mohammed A. S.), Arroyo, L. (Luzmila), Attorre, F. (Fabio), Aubin, I. (Isabelle), Banerjee, A. (Arindam), Bauters, M. (Marijn), Bergeron, Y. (Yves), Bergmeier, E. (Erwin), Biurrun, I. (Idoia), Bjorkman, A. D. (Anne D.), Bonari, G. (Gianmaria), Bondareva, V. (Viktoria), Brunet, J. (Jorg), Carni, A. (Andraz), Casella, L. (Laura), Cayuela, L. (Luis), Cerny, T. (Tomas), Chepinoga, V. (Victor), Csiky, J. (Janos), Custerevska, R. (Renata), De Bie, E. (Els), de Gasper, A. L. (Andre Luis), De Sanctis, M. (Michele), Dimopoulos, P. (Panayotis), Dolezal, J. (Jiri), Dziuba, T. (Tetiana), El-Sheikh, M. A. (Mohamed Abd El-Rouf Mousa), Enquist, B. (Brian), Ewald, J. (Joerg), Fazayeli, F. (Farideh), Field, R. (Richard), Finckh, M. (Manfred), Gachet, S. (Sophie), Galan-de-Mera, A. (Antonio), Garbolino, E. (Emmanuel), Gholizadeh, H. (Hamid), Giorgis, M. (Melisa), Golub, V. (Valentin), Alsos, I. G. (Inger Greve), Grytnes, J.-A. (John-Arvid), Guerin, G. R. (Gregory Richard), Gutierrez, A. G. (Alvaro G.), Haider, S. (Sylvia), Hatim, M. Z. (Mohamed Z.), Herault, B. (Bruno), Hinojos Mendoza, G. (Guillermo), Hoelzel, N. (Norbert), Homeier, J. (Juergen), Hubau, W. (Wannes), Indreica, A. (Adrian), Janssen, J. A. (John A. M.), Jedrzejek, B. (Birgit), Jentsch, A. (Anke), Juergens, N. (Norbert), Kacki, Z. (Zygmunt), Kapfer, J. (Jutta), Karger, D. N. (Dirk Nikolaus), Kavgaci, A. (Ali), Kearsley, E. (Elizabeth), Kessler, M. (Michael), Khanina, L. (Larisa), Killeen, T. (Timothy), Korolyuk, A. (Andrey), Kreft, H. (Holger), Kuehl, H. S. (Hjalmar S.), Kuzemko, A. (Anna), Landucci, F. (Flavia), Lengyel, A. (Attila), Lens, F. (Frederic), Lingner, D. V. (Debora Vanessa), Liu, H. (Hongyan), Lysenko, T. (Tatiana), Mahecha, M. D. (Miguel D.), Marceno, C. (Corrado), Martynenko, V. (Vasiliy), Moeslund, J. E. (Jesper Erenskjold), Monteagudo Mendoza, A. (Abel), Mucina, L. (Ladislav), Muller, J. V. (Jonas V.), Munzinger, J. (Jerome), Naqinezhad, A. (Alireza), Noroozi, J. (Jalil), Nowak, A. (Arkadiusz), Onyshchenko, V. (Viktor), Overbeck, G. E. (Gerhard E.), Partel, M. (Meelis), Pauchard, A. (Anibal), Peet, R. K. (Robert K.), Penuelas, J. (Josep), Perez-Haase, A. (Aaron), Peterka, T. (Tomas), Petrik, P. (Petr), Peyre, G. (Gwendolyn), Phillips, O. L. (Oliver L.), Prokhorov, V. (Vadim), Rasomavicius, V. (Valerijus), Revermann, R. (Rasmus), Rivas-Torres, G. (Gonzalo), Rodwell, J. S. (John S.), Ruprecht, E. (Eszter), Rusina, S. (Solvita), Samimi, C. (Cyrus), Schmidt, M. (Marco), Schrodt, F. (Franziska), Shan, H. (Hanhuai), Shirokikh, P. (Pavel), Sibik, J. (Jozef), Silc, U. (Urban), Sklenar, P. (Petr), Skvorc, Z. (Zeljko), Sparrow, B. (Ben), Sperandii, M. G. (Marta Gaia), Stancic, Z. (Zvjezdana), Svenning, J.-C. (Jens-Christian), Tang, Z. (Zhiyao), Tang, C. Q. (Cindy Q.), Tsiripidis, I. (Ioannis), Vanselow, K. A. (Kim Andre), Vasquez Martinez, R. (Rodolfo), Vassilev, K. (Kiril), Velez-Martin, E. (Eduardo), Venanzoni, R. (Roberto), Vibrans, A. C. (Alexander Christian), Violle, C. (Cyrille), Virtanen, R. (Risto), von Wehrden, H. (Henrik), Wagner, V. (Viktoria), Walker, D. A. (Donald A.), Waller, D. M. (Donald M.), Wang, H.-F. (Hua-Feng), Wesche, K. (Karsten), Whitfeld, T. J. (Timothy J. S.), Willner, W. (Wolfgang), Wiser, S. K. (Susan K.), Wohlgemuth, T. (Thomas), Yamalov, S. (Sergey), Zobel, M. (Martin), and Bruelheide, H. (Helge)
Abstract: Motivation: Assessing biodiversity status and trends in plant communities is critical for understanding, quantifying and predicting the effects of global change on ecosystems. Vegetation plots record the occurrence or abundance of all plant species co-occurring within delimited local areas. This allows species absences to be inferred, information seldom provided by existing global plant datasets. Although many vegetation plots have been recorded, most are not available to the global research community. A recent initiative, called ‘sPlot’, compiled the first global vegetation plot database, and continues to grow and curate it. The sPlot database, however, is extremely unbalanced spatially and environmentally, and is not open-access. Here, we address both these issues by (a) resampling the vegetation plots using several environmental variables as sampling strata and (b) securing permission from data holders of 105 local-to-regional datasets to openly release data. We thus present sPlotOpen, the largest open-access dataset of vegetation plots ever released. sPlotOpen can be used to explore global diversity at the plant community level, as ground truth data in remote sensing applications, or as a baseline for biodiversity monitoring. Main types of variable contained: Vegetation plots (n = 95,104) recording cover or abundance of naturally co-occurring vascular plant species within delimited areas. sPlotOpen contains three partially overlapping resampled datasets (c. 50,000 plots each), to be used as replicates in global analyses. Besides geographical location, date, plot size, biome, elevation, slope, aspect, vegetation type, naturalness, coverage of various vegetation layers, and source dataset, plot-level data also include community-weighted means and variances of 18 plant functional traits from the TRY Plant Trait Database. Spatial location and grain: Global, 0.01–40,000 m². Time period and grain: 1888–2015, recording dates. Major taxa and level of measuremen
Published: 2021

17. LncRNA UCA1 inhibits proliferation and promotes apoptosis of cervical cancer cells by regulating β-catenin/TCF-4

Author: D-M, Duan, L, Zhang, and F, Hua
Subjects: Tumor Cells, Cultured, Humans, Uterine Cervical Neoplasms, Apoptosis, Female, RNA, Long Noncoding, RNA, Messenger, Transcription Factor 7-Like 2 Protein, beta Catenin, Cell Proliferation, HeLa Cells
Abstract: The aim of this study was to explore the regulatory effect of long non-coding ribonucleic acid (lncRNA) urothelial carcinoma antigen 1 (UCA1) on the proliferation and apoptosis of HeLa cells and to elucidate its potential regulatory mechanism.HeLa cells were cultured in vitro and randomly divided into three groups, including blank control group (Control group), lncRNA UCA1 negative control (NC) group, and lncRNA UCA1 interference group [lncRNA UCA1 small interfering RNA (siRNA) group]. The expression level of lncRNA UCA1 in HeLa cells was detected by quantitative reverse transcription-polymerase chain reaction (qRT-PCR). Methyl thiazolyl tetrazolium (MTT) assay was performed to determine the effect of lncRNA UCA1 on the proliferation of HeLa cells. The effect of lncRNA UCA1 on the apoptosis of HeLa cells was determined via Hoechst 33258 staining assay and flow cytometry. In addition, qRT-PCR and Western blotting were employed to measure the messenger RNA (mRNA) and protein expression levels of β-catenin and TCF-4 in HeLa cells, respectively.There were no statistically significant differences in the proliferation and apoptosis of HeLa cells as well as the mRNA and protein levels of β-catenin and TCF-4 in HeLa cells between Control group and lncRNA UCA1 NC group (p0.05). In comparison with lncRNA UCA1 NC group, lncRNA UCA1 siRNA group exhibited overtly reduced proliferation, enhanced apoptosis rate of HeLa cells and down-regulated mRNA and protein levels of β-catenin and TCF-4 in HeLa cells (p0.05).LncRNA UCA1 inhibits proliferation and promotes the apoptosis of HeLa cells. Furthermore, its mechanism of action may be related to the inhibition on the β-catenin/TCF-4 signaling pathway.
Published: 2020

18. DS_10.1177_0022034520946025 – Supplemental material for Quality of Split-Mouth Trials in Dentistry: 1998, 2008, and 2018

Author: D. Qin, F. Hua, H. He, S. Liang, H. Worthington, and T. Walsh
Subjects: 110599 Dentistry not elsewhere classified, FOS: Materials engineering, FOS: Clinical medicine, 91299 Materials Engineering not elsewhere classified
Abstract: Supplemental material, DS_10.1177_0022034520946025 for Quality of Split-Mouth Trials in Dentistry: 1998, 2008, and 2018 by D. Qin, F. Hua, H. He, S. Liang, H. Worthington and T. Walsh in Journal of Dental Research
Published: 2020
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19. Phase 1, single‐dose escalating study of marzeptacog alfa (activated), a recombinant factor VIIa variant, in patients with severe hemophilia

Author: R.A. Gruppo, D. Malan, J. Kapocsi, L. Nemes, C.R.M. Hay, L. Boggio, P. Chowdary, G. Tagariello, A. von Drygalski, F. Hua, M. Scaramozza, S. Arkin, C.R.J.R. Hermans, C. Claes, I. Hanes, I. Huyghe, C. Kantaridis, L.M. da Costa, M.‐N. Ndongo, W. Petit, E.M. Santagostino, A. Cannavo, M.R. Fasulo, M.E. Mancuso, A. Tosetto, G. Castaman, L. Candiotto, P. Radossi, E. Scarpa, M.P. Smith, A.E. Dick, R.A. Robson, D.S. Waaka, C.J. Wynne, Z.E. Punt, K.R. Kavakli, C. Balkan, M. Duyu, S. Goksel, B. Karapinar, A.R. Ozyurek, G. Saydam, D.Y. Karapinar, M. Laffan, C.M. Millar, P.I. Suppiah, C.K. Rizleigh, G.P. Chowdary, J.S. Davies, E.L. Fosbury, S. Gill, G.N. Pike, J. Varghese Thachil, M. Recht, J. Deutsche, J. Taylor, K.A. Kalinyak, E.S. Mullins, J.S. Palumbo, C.T. Quinn, C. Tarango, S. Tarabar, P.A. Chandler, L. Deats, S.R. Deshpande, N.U. Epstein, A.G. Hansson, S.S. Pawlak, D. Rudin, L.A.J. Valentino, N.C. Kakodkar, M.L. Simpson, P.F. Fogarty, Tami L. Bach, Elaine Y. Chiang, J.W. Adamson, C.S. Glass, N. Sidhu, and T.D. Tucker‐Greene
Subjects: Adult, Male, 0301 basic medicine, Time Factors, Adolescent, Factor VIIa, 030204 cardiovascular system & hematology, Pharmacology, Hemophilia A, Hemophilia B, Severity of Illness Index, South Africa, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pharmacokinetics, medicine, Humans, Prothrombin time, biology, medicine.diagnostic_test, Factor VII, Coagulants, business.industry, Hematology, Middle Aged, Recombinant Proteins, United States, Europe, Treatment Outcome, 030104 developmental biology, chemistry, Tolerability, Recombinant factor VIIa, Pharmacodynamics, biology.protein, Administration, Intravenous, business, Partial thromboplastin time, Blood sampling
Abstract: Essentials Marzeptacog alfa (activated) [MarzAA] is a novel variant of activated human factor VII. A phase 1 dose escalation trial of MarzAA was conducted in subjects with severe hemophilia. MarzAA was safe and tolerated at intravenous doses up to 30 μg kg-1 Data observed support further trials for hemophilia patients with inhibitors to factors VIII/IX. Summary Background Marzeptacog alfa (activated) (MarzAA), a new recombinant activated human factor VII (rFVIIa) variant with four amino acid substitutions, was developed to provide increased procoagulant activity and a longer duration of action in people with hemophilia. Objectives To investigate the safety, tolerability, immunogenicity, pharmacokinetics (PK) and pharmacodynamics (PD) of single ascending intravenous bolus doses of MarzAA in non-bleeding patients with congenital hemophilia A or B with or without inhibitors. Methods This international, phase 1, open-label study (NCT01439971) enrolled males aged 18-64 years with severe hemophilia A or B, with or without FVIII or FIX inhibitors. Subjects were assigned to single-dose MarzAA cohorts (0.5, 4.5, 9, 18 or 30 μg kg-1 ). Blood sampling was performed predose and postdose, and subjects were monitored for 60 days postdose. Safety endpoints included adverse events, vital sign changes, electrocardiograms, laboratory abnormalities, and immunogenicity; secondary endpoints included evaluation of PK and PD. Results Overall, in 25 patients, MarzAA was well tolerated at all dose levels tested, and was not associated with dose-limiting toxicity. No treatment-emergent severe or serious adverse events occurred. MarzAA showed linear dose-response PK across the 4.5-30 μg kg-1 dose range, with a terminal half-life of ⁓ 3.5 h. Dose-dependent shortening of the activated partial thromboplastin time and prothrombin time, and evidence of an increase in peak thrombin as determined with a thrombin generation assay, were observed at all doses. Conclusions MarzAA was tolerated at doses up to 30 μg kg-1 . The safety profile and pharmacological effects observed support further clinical trials for the treatment of hemophilic patients with inhibitors.
Published: 2018
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20. Multi-objective optimization design of parallel manipulators using a neural network and principal component analysis

Author: C. Yang, P. Li, Y. Wang, W. Ye, T. Sun, F. Huang, and H. Zhang
Subjects: Materials of engineering and construction. Mechanics of materials, TA401-492
Abstract: In this work, a multi-objective optimization design method is proposed based on principal component analysis (PCA) and a neural network to obtain a mechanism's optimal comprehensive performance. First, multi-objective optimization mathematical modeling, including design parameters, objective functions, and constraint functions, is established. Second, the sample data are obtained through the design of the experiment (DOE) and are then standardized to eliminate the adverse effects of a non-uniform dimension of objective functions. Third, the first k principal components are established for p performance indices (k
Published: 2023
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21. Elevation of Vδ1 T cells in peripheral blood and livers of patients with primary biliary cholangitis

Author: Jing-Fang Zhang, Liang Wang, F Hua, Wei He, Fengchun Zhang, Ying Hu, and X Rong
Subjects: Male, 0301 basic medicine, Immunology, Lymphocyte Activation, Immunophenotyping, 03 medical and health sciences, 0302 clinical medicine, Primary biliary cirrhosis, T-Lymphocyte Subsets, Humans, Immunology and Allergy, Medicine, Lymphocyte Count, Autoimmune disease, medicine.diagnostic_test, Liver Cirrhosis, Biliary, business.industry, Active stage, Receptors, Antigen, T-Cell, gamma-delta, Original Articles, Middle Aged, medicine.disease, digestive system diseases, Peripheral blood, Ursodeoxycholic acid, Phenotype, 030104 developmental biology, Liver, Case-Control Studies, Liver biopsy, Etiology, Cytokines, Female, 030211 gastroenterology & hepatology, business, Biomarkers, Intracellular, medicine.drug
Abstract: Summary Primary biliary cholangitis (PBC), hitherto called primary biliary cirrhosis, is a cholestatic liver disease of unclear aetiology with autoimmune features. Accumulating evidence revealed that γδ T cells were involved in the development of autoimmune diseases. As one of γδ T cells subsets, however, the role of Vδ1 T cells in the immunopathogenesis of PBC is poorly understood. We analysed peripheral blood Vδ1 T cells in PBC patients in active stage (ASP, n = 18), adequate responders (AR, n = 10) and inadequate responders (IAR, n = 4) to ursodeoxycholic acid (UDCA) and an age-matched healthy control group (n = 16) by flow cytometric analysis. The ASP group exhibited a significantly higher proportion and absolute number of Vδ1 T cells, which were also observed in immunofluorescence staining of liver biopsy specimens of PBC patients. Moreover, these Vδ1 T cells expressed a series of activation markers and intracellular cytokines, which may contribute to the immunopathogenesis of PBC. Our study will help to clarify the role of Vδ1 T cells in the development of PBC.
Published: 2016
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22. GluR1 protects hypoxic ischemic brain damage via activating Akt signaling pathway in neonatal rats

Author: J-Z, Huang, Y, Ren, Y, Jiang, S-Y, Shen, J, Ding, and F, Hua
Subjects: Rats, Sprague-Dawley, Vascular Endothelial Growth Factor A, Animals, Newborn, Hypoxia-Ischemia, Brain, Animals, Brain, Apoptosis, Receptors, AMPA, Proto-Oncogene Proteins c-akt, Rats, Signal Transduction
Abstract: To investigate the role of glutamic acid receptor 1 (GluR1) in hypoxic-ischemic brain damage (HIBD) in neonatal rats and its underlying mechanism.7-day-old neonatal rats received right common carotid artery (CCA) ligation for the establishment of HIBD. After the operation, rats were sacrificed at different time points (0, 4, 6, 12, 24, 48, and 72 h), respectively. Meanwhile, rats in Sham group underwent similar procedures without ligation. Lentivirus-GLUR1-shRNA (LV-GLUR1 shRNA group) was constructed and then transfected into the right lateral ventricles of rats to inhibit GluR1 in vivo. Rats received LV-control injection were selected in the control group (LV-control group). After injection of Lentivirus-GLUR1-shRNA, CCA ligation was performed in rats for HIBD construction. Western blot was performed to detect the protein levels of GLUR1, Akt, p-Akt, and vascular endothelial growth factor (VEGF) in brain tissues. Cell apoptosis was measured by TUNEL staining assay.After hypoxic ischemia (HI), GLUR1 expression increased gradually and reached a peak at 24 h. Meanwhile, p-Akt expression increased immediately and then gradually decreased. 24 h later, p-Akt expression increased again and peaked at 48 h. VEGF expression increased at 4 h after HI and reached a peak at 12 h. The expression levels of GLUR1, p-Akt, and VEGF in the brain tissues derived from rats transfected with LV-GLUR1 shRNA significantly decreased at both 4 h and 24 h after HI. In addition, results indicated that cell apoptosis was enhanced after LV-GLUR1 shRNA administration, suggesting the role of GLUR1 in protecting against HIBD.GLUR1 exhibits a remarkable protective role in HIBD, which may be related to the activation of the Akt signaling pathway and the upregulation of VEGF after HI.
Published: 2018

23. [Analyzing the social impact of orthodontic articles published by Chinese authors in international journals during the past five years]

Author: Y, Mei, F, Hua, and H, He
Subjects: China, Internationality, Time Factors, Databases, Factual, Bibliometrics, Dental Research, Orthodontics, Journal Impact Factor, Social Change, Authorship
Published: 2018

24. MULTI-BASELINE INSAR ELEVATION INVERSION METHOD BASED ON THREE-DIMENSIONAL RECONSTRUCTION MODEL

Author: F. Hua, L. Lu, Z. Wang, and G. Peng
Subjects: lcsh:Applied optics. Photonics, Interferometric phase, lcsh:T, 0211 other engineering and technologies, Elevation, lcsh:TA1501-1820, Inverse transform sampling, 02 engineering and technology, Geodesy, lcsh:Technology, Interferometry, Geography, lcsh:TA1-2040, Interferometric synthetic aperture radar, lcsh:Engineering (General). Civil engineering (General), Baseline (configuration management), Geometric modeling, Algorithm, 021101 geological & geomatics engineering, Integer (computer science)
Abstract: The existing multi-baseline methods have some problems of low accuracy and intensive calculation. In order to solve the problems, a new multi-baseline InSAR elevation inversion method based on a rigorous geometric model instead of a simplified model is proposed in the letter. This method introduces the three-dimensional reconstruction model based on rigorous geometric model and the unknown full cycles of interferometric phase as a parameter to iteratively solve the 3-D coordinates of the target. With adopting the 3-D coordinate information of targets to connect different interferometric data, the new method obviously weakens the effects of system errors on solving the integer cycle and is more reliable than conventional multi-baseline InSAR methods. The experimental results show that the speed and accuracy of the new method are better than the existing methods.
Published: 2018

25. MULTI-ROBOT COOPERATIVE LIDAR SLAM FOR EFFICIENT MAPPING IN URBAN SCENES

Author: Y. Sun, F. Huang, W. Wen, L.-T. Hsu, and X. Liu
Subjects: Technology, Engineering (General). Civil engineering (General), TA1-2040, Applied optics. Photonics, TA1501-1820
Abstract: We first use the multi-robot SLAM framework DiSCo-SLAM to evaluate the performance of cooperative SLAM based on the complicated dataset in urban scenes. Besides, we perform comparisons of single-robot SLAM and multi-robot SLAM to explore whether the cooperative framework can noticeably improve robot localization performance and the influence of inter-robot constraints in local pose graph, utilizing an identical dataset generated via the Carla simulator. Our findings indicate that under specific conditions, the integration of inter-robot constraints may effectively mitigate drift in local pose estimation. The extent to which inter-robot constraints affect the correction of local SLAM is related to various factors, such as the confidence level of the constraints and the range of keyframes imposed by the constraint.
Published: 2023
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26. First observation of the cosmic ray shadow of the Moon and the Sun with KM3NeT/ORCA

Author: S. Aiello, A. Albert, S. Alves Garre, Z. Aly, A. Ambrosone, F. Ameli, M. Andre, M. Anghinolfi, M. Anguita, M. Ardid, S. Ardid, J. Aublin, C. Bagatelas, L. Bailly-Salins, B. Baret, S. Basegmez du Pree, Y. Becherini, M. Bendahman, F. Benfenati, E. Berbee, V. Bertin, S. Biagi, M. Boettcher, M. Bou Cabo, J. Boumaaza, M. Bouta, M. Bouwhuis, C. Bozza, H. Brânzaş, R. Bruijn, J. Brunner, R. Bruno, E. Buis, R. Buompane, J. Busto, B. Caiffi, D. Calvo, S. Campion, A. Capone, F. Carenini, V. Carretero, P. Castaldi, S. Celli, L. Cerisy, M. Chabab, N. Chau, A. Chen, R. Cherkaoui El Moursli, S. Cherubini, V. Chiarella, T. Chiarusi, M. Circella, R. Cocimano, J. A. B. Coelho, A. Coleiro, R. Coniglione, P. Coyle, A. Creusot, A. Cruz, G. Cuttone, R. Dallier, Y. Darras, A. De Benedittis, B. De Martino, R. Del Burgo, I. Di Palma, A. F. Dìaz, D. Diego-Tortosa, C. Distefano, A. Domi, C. Donzaud, D. Dornic, M. Dörr, E. Drakopoulou, D. Drouhin, T. Eberl, A. Eddyamoui, T. van Eeden, M. Eff, D. van Eijk, I. El Bojaddaini, S. El Hedri, A. Enzenhöfer, V. Espinosa, G. Ferrara, M. D. Filipović, F. Filippini, L. A. Fusco, J. Gabriel, T. Gal, J. García Méndez, A. Garcia Soto, F. Garufi, C. Gatius Oliver, N. Geißelbrecht, L. Gialanella, E. Giorgio, A. Girardi, I. Goos, S. R. Gozzini, R. Gracia, K. Graf, D. Guderian, C. Guidi, B. Guillon, M. Gutiérrez, L. Haegel, H. van Haren, A. Heijboer, A. Hekalo, L. Hennig, J. J. Hernández-Rey, F. Huang, W. Idrissi Ibnsalih, G. Illuminati, C. W. James, D. Janezashvili, M. de Jong, P. de Jong, B. J. Jung, P. Kalaczyński, O. Kalekin, U. F. Katz, N. R. Khan Chowdhury, G. Kistauri, F. van der Knaap, P. Kooijman, A. Kouchner, V. Kulikovskiy, M. Labalme, R. Lahmann, A. Lakhal, M. Lamoureux, G. Larosa, C. Lastoria, A. Lazo, R. Le Breton, S. Le Stum, G. Lehaut, E. Leonora, N. Lessing, G. Levi, S. Liang, M. Lindsey Clark, F. Longhitano, L. Maderer, J. Majumdar, J. Mańczak, A. Margiotta, A. Marinelli, C. Markou, L. Martin, J. A. Martínez-Mora, A. Martini, F. Marzaioli, M. Mastrodicasa, S. Mastroianni, K. W. Melis, S. Miccichè, G. Miele, P. Migliozzi, E. Migneco, P. Mijakowski, C. M. Mollo, L. Morales-Gallegos, C. Morley-Wong, A. Moussa, R. Muller, M. R. Musone, M. Musumeci, L. Nauta, S. Navas, C. A. Nicolau, B. Nkosi, B. Ó. Fearraigh, A. Orlando, E. Oukacha, J. Palacios González, G. Papalashvili, R. Papaleo, E. J. Pastor Gomez, A. M. Păun, G. E. Păvălaş, C. Pellegrino, S. Peña Martínez, M. Perrin-Terrin, J. Perronnel, V. Pestel, P. Piattelli, O. Pisanti, C. Poirè, V. Popa, T. Pradier, S. Pulvirenti, G. Quéméner, U. Rahaman, N. Randazzo, S. Razzaque, I. C. Rea, D. Real, S. Reck, G. Riccobene, J. Robinson, A. Romanov, F. Salesa Greus, D. F. E. Samtleben, A. Sánchez Losa, M. Sanguineti, C. Santonastaso, D. Santonocito, P. Sapienza, A. Sathe, J. Schnabel, M. F. Schneider, J. Schumann, H. M. Schutte, J. Seneca, I. Sgura, R. Shanidze, A. Sharma, A. Simonelli, A. Sinopoulou, M. V. Smirnov, B. Spisso, M. Spurio, D. Stavropoulos, S. M. Stellacci, M. Taiuti, K. Tavzarashvili, Y. Tayalati, H. Tedjditi, H. Thiersen, S. Tsagkli, V. Tsourapis, E. Tzamariudaki, V. Van Elewyck, G. Vannoye, G. Vasileiadis, F. Versari, S. Viola, D. Vivolo, H. Warnhofer, J. Wilms, E. de Wolf, H. Yepes-Ramirez, T. Yousfi, S. Zavatarelli, A. Zegarelli, D. Zito, J. D. Zornoza, J. Zúñiga, and N. Zywucka
Subjects: Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract: Abstract This article reports the first observation of the Moon and the Sun shadows in the sky distribution of cosmic-ray induced muons measured by the KM3NeT/ORCA detector. The analysed data-taking period spans from February 2020 to November 2021, when the detector had 6 Detection Units deployed at the bottom of the Mediterranean Sea, each composed of 18 Digital Optical Modules. The shadows induced by the Moon and the Sun were detected at their nominal position with a statistical significance of 4.2 $$\sigma $$ σ and 6.2 $$\sigma $$ σ , and an angular resolution of $$\sigma _{res}=0.49^\circ $$ σ res = 0 . 49 ∘ and $$\sigma _{res}=0.66^\circ $$ σ res = 0 . 66 ∘ , respectively, consistent with the prediction of $$0.53^\circ $$ 0 . 53 ∘ from simulations. This early result confirms the effectiveness of the detector calibration, in time, position and orientation and the accuracy of the event direction reconstruction. This also demonstrates the performance and the competitiveness of the detector in terms of pointing accuracy and angular resolution.
Published: 2023
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27. Probing invisible neutrino decay with KM3NeT/ORCA

Author: The KM3NeT collaboration, S. Aiello, A. Albert, S. Alves Garre, Z. Aly, A. Ambrosone, F. Ameli, M. Andre, M. Anghinolfi, M. Anguita, M. Ardid, S. Ardid, J. Aublin, C. Bagatelas, L. Bailly-Salins, B. Baret, S. Basegmez du Pree, Y. Becherini, M. Bendahman, F. Benfenati, E. Berbee, V. Bertin, S. Biagi, M. Boettcher, M. Bou Cabo, J. Boumaaza, M. Bouta, M. Bouwhuis, C. Bozza, H. Brânzaş, R. Bruijn, J. Brunner, R. Bruno, E. Buis, R. Buompane, J. Busto, B. Caiffi, D. Calvo, S. Campion, A. Capone, F. Carenini, V. Carretero, P. Castaldi, S. Celli, L. Cerisy, M. Chabab, N. Chau, A. Chen, R. Cherkaoui El Moursli, S. Cherubini, V. Chiarella, T. Chiarusi, M. Circella, R. Cocimano, J. A. B. Coelho, A. Coleiro, R. Coniglione, P. Coyle, A. Creusot, A. Cruz, G. Cuttone, R. Dallier, Y. Darras, A. De Benedittis, B. De Martino, V. Decoene, R. Del Burgo, I. Di Palma, A. F. Díaz, D. Diego-Tortosa, C. Distefano, A. Domi, C. Donzaud, D. Dornic, M. Dörr, E. Drakopoulou, D. Drouhin, T. Eberl, A. Eddyamoui, T. van Eeden, M. Eff, D. van Eijk, I. El Bojaddaini, S. El Hedri, A. Enzenhöfer, V. Espinosa, G. Ferrara, M. D. Filipović, F. Filippini, L. A. Fusco, J. Gabriel, T. Gal, J. García Méndez, A. Garcia Soto, F. Garufi, C. Gatius Oliver, N. Geißelbrecht, L. Gialanella, E. Giorgio, A. Girardi, I. Goos, S. R. Gozzini, R. Gracia, K. Graf, D. Guderian, C. Guidi, B. Guillon, M. Gutiérrez, L. Haegel, H. van Haren, A. Heijboer, A. Hekalo, L. Hennig, J. J. Hernández-Rey, F. Huang, W. Idrissi Ibnsalih, G. Illuminati, C. W. James, D. Janezashvili, M. de Jong, P. de Jong, B. J. Jung, P. Kalaczyński, O. Kalekin, U. F. Katz, N. R. Khan Chowdhury, G. Kistauri, F. van der Knaap, P. Kooijman, A. Kouchner, V. Kulikovskiy, M. Labalme, R. Lahmann, A. Lakhal, M. Lamoureux, G. Larosa, C. Lastoria, A. Lazo, R. Le Breton, S. Le Stum, G. Lehaut, E. Leonora, N. Lessing, G. Levi, S. Liang, M. Lindsey Clark, F. Longhitano, L. Maderer, J. Majumdar, J. Mańczak, A. Margiotta, A. Marinelli, C. Markou, L. Martin, J. A. Martínez-Mora, A. Martini, F. Marzaioli, M. Mastrodicasa, S. Mastroianni, K. W. Melis, S. Miccichè, G. Miele, P. Migliozzi, E. Migneco, P. Mijakowski, C. M. Mollo, L. Morales-Gallegos, C. Morley-Wong, A. Moussa, R. Muller, M. R. Musone, M. Musumeci, L. Nauta, S. Navas, C. A. Nicolau, B. Nkosi, B. Ó Fearraigh, A. Orlando, E. Oukacha, J. Palacios González, G. Papalashvili, R. Papaleo, E. J. Pastor Gomez, A. M. Păun, G. E. Păvălaş, C. Pellegrino, S. Peña Martínez, M. Perrin-Terrin, J. Perronnel, V. Pestel, P. Piattelli, O. Pisanti, C. Poirè, V. Popa, T. Pradier, S. Pulvirenti, G. Quéméner, U. Rahaman, N. Randazzo, S. Razzaque, I. C. Rea, D. Real, S. Reck, G. Riccobene, J. Robinson, A. Romanov, F. Salesa Greus, D. F. E. Samtleben, A. Sánchez Losa, M. Sanguineti, C. Santonastaso, D. Santonocito, P. Sapienza, A. Sathe, J. Schnabel, M. F. Schneider, J. Schumann, H. M. Schutte, J. Seneca, I. Sgura, R. Shanidze, A. Sharma, A. Simonelli, A. Sinopoulou, M. V. Smirnov, B. Spisso, M. Spurio, D. Stavropoulos, S. M. Stellacci, M. Taiuti, K. Tavzarashvili, Y. Tayalati, H. Tedjditi, T. Thakore, H. Thiersen, S. Tsagkli, V. Tsourapis, E. Tzamariudaki, V. Van Elewyck, G. Vannoye, G. Vasileiadis, F. Versari, S. Viola, D. Vivolo, H. Warnhofer, J. Wilms, E. de Wolf, H. Yepes-Ramirez, T. Yousfi, S. Zavatarelli, A. Zegarelli, D. Zito, J. D. Zornoza, J. Zúñiga, and N. Zywucka
Subjects: Beyond Standard Model, Neutrino Detectors and Telescopes (experiments), Oscillation, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract: Abstract In the era of precision measurements of the neutrino oscillation parameters, upcoming neutrino experiments will also be sensitive to physics beyond the Standard Model. KM3NeT/ORCA is a neutrino detector optimised for measuring atmospheric neutrinos from a few GeV to around 100 GeV. In this paper, the sensitivity of the KM3NeT/ORCA detector to neutrino decay has been explored. A three-flavour neutrino oscillation scenario, where the third neutrino mass state ν 3 decays into an invisible state, e.g. a sterile neutrino, is considered. We find that KM3NeT/ORCA would be sensitive to invisible neutrino decays with 1/α 3 = τ 3 /m 3 < 180 ps/eV at 90% confidence level, assuming true normal ordering. Finally, the impact of neutrino decay on the precision of KM3NeT/ORCA measurements for θ 23, Δ m 31 2 $$ \Delta {m}_{31}^2 $$ and mass ordering have been studied. No significant effect of neutrino decay on the sensitivity to these measurements has been found.
Published: 2023
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28. Wafer-shape metrics based foundry lithography

Author: Sean Lee, Jeffrey Mileham, C. F. Hua, Sungtae Kim, Ming Sheng Wei, Eric Bouche, Damon Tsai, Frida Liang, and Albert Huang
Subjects: 010302 applied physics, Depth of focus, Fabrication, Computer science, 02 engineering and technology, Lithography process, 021001 nanoscience & nanotechnology, 01 natural sciences, Metrology, Interferometry, Distortion, 0103 physical sciences, Hardware_INTEGRATEDCIRCUITS, Electronic engineering, Wafer, 0210 nano-technology, Lithography
Abstract: As device shrink, there are many difficulties with process integration and device yield. Lithography process control is expected to be a major challenge due to tighter overlay and focus control requirement. The understanding and control of stresses accumulated during device fabrication has becoming more critical at advanced technology nodes. Within-wafer stress variations cause local wafer distortions which in turn present challenges for managing overlay and depth of focus during lithography. A novel technique for measuring distortion is Coherent Gradient Sensing (CGS) interferometry, which is capable of generating a high-density distortion data set of the full wafer within a time frame suitable for a high volume manufacturing (HVM) environment. In this paper, we describe the adoption of CGS (Coherent Gradient Sensing) interferometry into high volume foundry manufacturing to overcome these challenges. Leveraging this high density 3D metrology, we characterized its In-plane distortion as well as its topography capabilities applied to the full flow of an advanced foundry manufacturing. Case studies are presented that summarize the use of CGS data to reveal correlations between in-plane distortion and overlay variation as well as between topography and device yield.
Published: 2017
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29. [Experiences of rescuing infective arterial hemorrhage and pseudoaneurysm in DCD kidney transplantation]

Author: D D, Zhao, L Q, Hong, Z Y, Huang, N, Na, X F, Hua, B, Miao, H, Li, and Q Q, Sun
Subjects: Death, Mycoses, Risk Factors, Graft Survival, Humans, Hemorrhage, Arteries, Kidney, Kidney Transplantation, Nephrectomy, Aneurysm, False, Tissue Donors, Retrospective Studies
Published: 2017

30. The Critical Axial Force Model in Drilling of Carbon Fiber Reinforced Composites under Different Stacking Modes

Author: Tian Wei, Wenhe Liao, F F Hua, Long Zhang, Zhongfan Liu, M Li, and H L Sun
Subjects: 0209 industrial biotechnology, Materials science, Delamination, Composite number, Stacking, Drilling, 02 engineering and technology, Bending of plates, Superposition principle, 020303 mechanical engineering & transports, 020901 industrial engineering & automation, 0203 mechanical engineering, Axial force, Composite material, Failure mode and effects analysis
Abstract: Delamination is a failure mode in which the initial crack propagates along the interlayer due to the axial force pushing the uncut material beyond the interlaminar shear strength during drilling. Therefore, it is necessary to study the effect of axial force on the delamination of carbon fiber reinforced composites (CFRP) during drilling. The critical axial force model of different stacking modes is established based on linear elastic fracture mechanics, thin plate bending theory, composite mechanics and superposition principle. The experimental results show that the theoretical values are in good agreement with the experimental values and can be used to predict the critical axial force to suppress the formation of delamination defects.
Published: 2019
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31. A 1 km daily soil moisture dataset over China using in situ measurement and machine learning

Author: Q. Li, G. Shi, W. Shangguan, V. Nourani, J. Li, L. Li, F. Huang, Y. Zhang, C. Wang, D. Wang, J. Qiu, X. Lu, and Y. Dai
Subjects: Environmental sciences, GE1-350, Geology, QE1-996.5
Abstract: High-quality gridded soil moisture products are essential for many Earth system science applications, while the recent reanalysis and remote sensing soil moisture data are often available at coarse resolution and remote sensing data are only for the surface soil. Here, we present a 1 km resolution long-term dataset of soil moisture derived through machine learning trained by the in situ measurements of 1789 stations over China, named SMCI1.0 (Soil Moisture of China by in situ data, version 1.0). Random forest is used as a robust machine learning approach to predict soil moisture using ERA5-Land time series, leaf area index, land cover type, topography and soil properties as predictors. SMCI1.0 provides 10-layer soil moisture with 10 cm intervals up to 100 cm deep at daily resolution over the period 2000–2020. Using in situ soil moisture as the benchmark, two independent experiments were conducted to evaluate the estimation accuracy of SMCI1.0: year-to-year (ubRMSE ranges from 0.041 to 0.052 and R ranges from 0.883 to 0.919) and station-to-station experiments (ubRMSE ranges from 0.045 to 0.051 and R ranges from 0.866 to 0.893). SMCI1.0 generally has advantages over other gridded soil moisture products, including ERA5-Land, SMAP-L4, and SoMo.ml. However, the high errors of soil moisture are often located in the North China Monsoon Region. Overall, the highly accurate estimations of both the year-to-year and station-to-station experiments ensure the applicability of SMCI1.0 to study the spatial–temporal patterns. As SMCI1.0 is based on in situ data, it can be a useful complement to existing model-based and satellite-based soil moisture datasets for various hydrological, meteorological, and ecological analyses and models. The DOI link for the dataset is http://dx.doi.org/10.11888/Terre.tpdc.272415 (Shangguan et al., 2022).
Published: 2022
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32. Detection of astrophysical tau neutrino candidates in IceCube

Author: IceCube Collaboration, R. Abbasi, M. Ackermann, J. Adams, J. A. Aguilar, M. Ahlers, M. Ahrens, C. Alispach, A. A. Alves, N. M. Amin, K. Andeen, T. Anderson, I. Ansseau, G. Anton, C. Argüelles, S. Axani, X. Bai, A. V. Balagopal, A. Barbano, S. W. Barwick, B. Bastian, V. Basu, V. Baum, S. Baur, R. Bay, J. J. Beatty, K.-H. Becker, J. Becker Tjus, C. Bellenghi, S. BenZvi, D. Berley, E. Bernardini, D. Z. Besson, G. Binder, D. Bindig, E. Blaufuss, S. Blot, S. Böser, O. Botner, J. Böttcher, E. Bourbeau, J. Bourbeau, F. Bradascio, J. Braun, S. Bron, J. Brostean-Kaiser, A. Burgman, R. S. Busse, M. A. Campana, C. Chen, D. Chirkin, S. Choi, B. A. Clark, K. Clark, L. Classen, A. Coleman, G. H. Collin, J. M. Conrad, P. Coppin, P. Correa, D. F. Cowen, R. Cross, P. Dave, C. De Clercq, J. J. DeLaunay, H. Dembinski, K. Deoskar, S. De Ridder, A. Desai, P. Desiati, K. D. de Vries, G. de Wasseige, M. de With, T. DeYoung, S. Dharani, A. Diaz, J. C. Díaz-Vélez, H. Dujmovic, M. Dunkman, M. A. DuVernois, E. Dvorak, T. Ehrhardt, P. Eller, R. Engel, J. Evans, P. A. Evenson, S. Fahey, A. R. Fazely, S. Fiedlschuster, A. T. Fienberg, K. Filimonov, C. Finley, L. Fischer, D. Fox, A. Franckowiak, E. Friedman, A. Fritz, P. Fürst, T. K. Gaisser, J. Gallagher, E. Ganster, S. Garrappa, L. Gerhardt, A. Ghadimi, T. Glauch, T. Glüsenkamp, A. Goldschmidt, J. G. Gonzalez, S. Goswami, D. Grant, T. Grégoire, Z. Griffith, S. Griswold, M. Gündüz, C. Haack, A. Hallgren, R. Halliday, L. Halve, F. Halzen, M. Ha Minh, K. Hanson, J. Hardin, A. Haungs, S. Hauser, D. Hebecker, K. Helbing, F. Henningsen, S. Hickford, J. Hignight, C. Hill, G. C. Hill, K. D. Hoffman, R. Hoffmann, T. Hoinka, B. Hokanson-Fasig, K. Hoshina, F. Huang, M. Huber, T. Huber, K. Hultqvist, M. Hünnefeld, R. Hussain, S. In, N. Iovine, A. Ishihara, M. Jansson, G. S. Japaridze, M. Jeong, B. J. P. Jones, R. Joppe, D. Kang, W. Kang, X. Kang, A. Kappes, D. Kappesser, T. Karg, M. Karl, A. Karle, U. Katz, M. Kauer, M. Kellermann, J. L. Kelley, A. Kheirandish, J. Kim, K. Kin, T. Kintscher, J. Kiryluk, S. R. Klein, R. Koirala, H. Kolanoski, L. Köpke, C. Kopper, S. Kopper, D. J. Koskinen, P. Koundal, M. Kovacevich, M. Kowalski, K. Krings, G. Krückl, N. Kulacz, N. Kurahashi, A. Kyriacou, C. Lagunas Gualda, J. L. Lanfranchi, M. J. Larson, F. Lauber, J. P. Lazar, K. Leonard, A. Leszczyńska, Y. Li, Q. R. Liu, E. Lohfink, C. J. Lozano Mariscal, L. Lu, F. Lucarelli, A. Ludwig, W. Luszczak, Y. Lyu, W. Y. Ma, J. Madsen, K. B. M. Mahn, Y. Makino, P. Mallik, S. Mancina, I. C. Mariş, R. Maruyama, K. Mase, F. McNally, K. Meagher, A. Medina, M. Meier, S. Meighen-Berger, J. Merz, J. Micallef, D. Mockler, G. Momenté, T. Montaruli, R. W. Moore, R. Morse, M. Moulai, R. Naab, R. Nagai, U. Naumann, J. Necker, G. Neer, L. V. Nguyễn, H. Niederhausen, M. U. Nisa, S. C. Nowicki, D. R. Nygren, A. Obertacke Pollmann, M. Oehler, A. Olivas, E. O’Sullivan, H. Pandya, D. V. Pankova, N. Park, G. K. Parker, E. N. Paudel, P. Peiffer, C. Pérez de los Heros, S. Philippen, D. Pieloth, S. Pieper, A. Pizzuto, M. Plum, Y. Popovych, A. Porcelli, M. Prado Rodriguez, P. B. Price, G. T. Przybylski, C. Raab, A. Raissi, M. Rameez, K. Rawlins, I. C. Rea, A. Rehman, R. Reimann, M. Renschler, G. Renzi, E. Resconi, S. Reusch, W. Rhode, M. Richman, B. Riedel, S. Robertson, G. Roellinghoff, M. Rongen, C. Rott, T. Ruhe, D. Ryckbosch, D. Rysewyk Cantu, I. Safa, S. E. Sanchez Herrera, A. Sandrock, J. Sandroos, M. Santander, S. Sarkar, K. Satalecka, M. Scharf, M. Schaufel, H. Schieler, P. Schlunder, T. Schmidt, A. Schneider, J. Schneider, F. G. Schröder, L. Schumacher, S. Sclafani, D. Seckel, S. Seunarine, S. Shefali, M. Silva, B. Smithers, R. Snihur, J. Soedingrekso, D. Soldin, G. M. Spiczak, C. Spiering, J. Stachurska, M. Stamatikos, T. Stanev, R. Stein, J. Stettner, A. Steuer, T. Stezelberger, R. G. Stokstad, N. L. Strotjohann, T. Stuttard, G. W. Sullivan, I. Taboada, F. Tenholt, S. Ter-Antonyan, S. Tilav, F. Tischbein, K. Tollefson, L. Tomankova, C. Tönnis, S. Toscano, D. Tosi, A. Trettin, M. Tselengidou, C. F. Tung, A. Turcati, R. Turcotte, C. F. Turley, J. P. Twagirayezu, B. Ty, E. Unger, M. A. Unland Elorrieta, M. Usner, J. Vandenbroucke, D. van Eijk, N. van Eijndhoven, D. Vannerom, J. van Santen, S. Verpoest, M. Vraeghe, C. Walck, A. Wallace, N. Wandkowsky, T. B. Watson, C. Weaver, A. Weindl, M. J. Weiss, J. Weldert, C. Wendt, J. Werthebach, M. Weyrauch, B. J. Whelan, N. Whitehorn, K. Wiebe, C. H. Wiebusch, D. R. Williams, M. Wolf, T. R. Wood, K. Woschnagg, G. Wrede, J. Wulff, X. W. Xu, Y. Xu, J. P. Yanez, S. Yoshida, T. Yuan, and Z. Zhang
Subjects: Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract: Abstract High-energy tau neutrinos are rarely produced in atmospheric cosmic-ray showers or at cosmic particle accelerators, but are expected to emerge during neutrino propagation over cosmic distances due to flavor mixing. When high energy tau neutrinos interact inside the IceCube detector, two spatially separated energy depositions may be resolved, the first from the charged current interaction and the second from the tau lepton decay. We report a novel analysis of 7.5 years of IceCube data that identifies two candidate tau neutrinos among the 60 “High-Energy Starting Events” (HESE) collected during that period. The HESE sample offers high purity, all-sky sensitivity, and distinct observational signatures for each neutrino flavor, enabling a new measurement of the flavor composition. The measured astrophysical neutrino flavor composition is consistent with expectations, and an astrophysical tau neutrino flux is indicated at 2.8 $$\sigma $$ σ significance.
Published: 2022
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33. Glasgow University Surgical Society, Undergraduate Surgical Conference, 3 November 2012

Author: John Kinsella and F. Hua Liat Hii
Subjects: Bioengineered skin, medicine.medical_specialty, Burn wound, business.industry, Medicine, General Medicine, business, Dermatology, Surgery
Published: 2013
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34. Searches for Neutrinos in the Direction of Radio-bright Blazars with the ANTARES Telescope

Author: A. Albert, S. Alves, M. André, M. Ardid, S. Ardid, J.-J. Aubert, J. Aublin, B. Baret, S. Basa, Y. Becherini, B. Belhorma, M. Bendahman, F. Benfenati, V. Bertin, S. Biagi, M. Bissinger, J. Boumaaza, M. Bouta, M. C. Bouwhuis, H. Brânzaş, R. Bruijn, J. Brunner, J. Busto, B. Caiffi, D. Calvo, S. Campion, A. Capone, L. Caramete, F. Carenini, J. Carr, V. Carretero, S. Celli, L. Cerisy, M. Chabab, R. Cherkaoui El Moursli, T. Chiarusi, M. Circella, J. A. B. Coelho, A. Coleiro, R. Coniglione, P. Coyle, A. Creusot, A. S. M. Cruz, A. F. Díaz, B. De Martino, C. Distefano, I. Di Palma, A. Domi, C. Donzaud, D. Dornic, D. Drouhin, T. Eberl, T. van Eeden, D. van Eijk, S. El Hedri, N. El Khayati, A. Enzenhöfer, P. Fermani, G. Ferrara, F. Filippini, L. Fusco, S. Gagliardini, J. García, C. Gatius Oliver, P. Gay, N. Geißelbrecht, H. Glotin, R. Gozzini, R. Gracia Ruiz, K. Graf, C. Guidi, L. Haegel, S. Hallmann, H. van Haren, A. J. Heijboer, Y. Hello, J. J. Hernández-Rey, J. Hößl, J. Hofestädt, F. Huang, G. Illuminati, C. W. James, B. Jisse-Jung, M. de Jong, P. de Jong, M. Kadler, O. Kalekin, U. Katz, A. Kouchner, Y. A Kovalev, Y. Y Kovalev, I. Kreykenbohm, V. Kulikovskiy, R. Lahmann, M. Lamoureux, A. Lazo, D. Lefèvre, E. Leonora, G. Levi, S. Le Stum, D. Lopez-Coto, S. Loucatos, L. Maderer, J. Manczak, M. Marcelin, A. Margiotta, A. Marinelli, J. A. Martínez-Mora, P. Migliozzi, A. Moussa, R. Muller, S. Navas, E. Nezri, B. Ó Fearraigh, E. Oukacha, A. Păun, G. E. Păvălaş, S. Peña-Martínez, M. Perrin-Terrin, V. Pestel, P. Piattelli, A. Plavin, C. Poirè, V. Popa, T. Pradier, A. Pushkarev, N. Randazzo, D. Real, S. Reck, G. Riccobene, A. Romanov, A. Sánchez-Losa, A. Saina, F. Salesa Greus, D. F. E. Samtleben, M. Sanguineti, P. Sapienza, J. Schnabel, J. Schumann, F. Schüssler, J. Seneca, M. Spurio, Th. Stolarczyk, M. Taiuti, Y. Tayalati, S. J. Tingay, S. Troitsky, B. Vallage, G. Vannoye, V. Van Elewyck, S. Viola, D. Vivolo, J. Wilms, S. Zavatarelli, A. Zegarelli, J. D. Zornoza, J. Zúñiga, ANTARES Collaboration, T. Hovatta, S. Kiehlmann, I. Liodakis, V. Pavlidou, A. C. S Readhead, and OVRO Collaboration
Subjects: Neutrino astronomy, Blazars, Astrophysics, QB460-466
Abstract: Active galaxies, especially blazars, are among the most promising extragalactic candidates for high-energy neutrino sources. To date, ANTARES searches included these objects and used GeV–TeV γ -ray flux to select blazars. Here, a statistically complete blazar sample selected by their bright radio emission is used as the target for searches of origins of neutrinos collected by the ANTARES neutrino telescope over 13 yr of operation. The hypothesis of a neutrino–blazar directional correlation is tested by pair counting and a complementary likelihood-based approach. The resulting posttrial p -value is 3.0% (2.2 σ in the two-sided convention). Additionally, a time-dependent analysis is performed to search for temporal clustering of neutrino candidates as a means of detecting neutrino flares in blazars. None of the investigated sources alone reaches a significant flare detection level. However, the presence of 18 sources with a pretrial significance above 3 σ indicates a p = 1.4% (2.5 σ in the two-sided convention) detection of a time-variable neutrino flux. An a posteriori investigation reveals an intriguing temporal coincidence of neutrino, radio, and γ -ray flares of the J0242+1101 blazar at a p = 0.5% (2.9 σ in the two-sided convention) level. Altogether, the results presented here suggest a possible connection of neutrino candidates detected by the ANTARES telescope with radio-bright blazars.
Published: 2024
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35. The expression research of miR-210 in the elderly patients with COPD combined with ischemic stroke

Author: L-Q, Wang, C-L, Wang, L-N, Xu, and D-F, Hua
Subjects: Stroke, MicroRNAs, Pulmonary Disease, Chronic Obstructive, ROC Curve, Down-Regulation, Humans, Biomarkers, Aged
Abstract: We conduct this study to investigate the expression level of miR-210 in elderly patients with COPD combined with ischemic stroke and analyzed its application value as a sensitive diagnostic indicator.50 cases of elderly patients with COPD combined with ischemic stroke were selected as group A, 50 cases of elderly patients with COPD were selected as group B, 50 cases of elderly patients with ischemic stroke were selected as group C, and 50 cases of healthy volunteers as group D. Real-time PCR assay for quantification was used to detect the expression level of miR-210 in peripheral blood and receiver operating curve (ROC) was used to analyze the diagnostic sensitivity and accuracy.MiR-210 level of group A was the lowest, followed by group B and group C; group D had the highest levels. The difference was statistically significant (p0.05). MiR-210 levels decreased with an increasing decline degree of lung function and the difference was statistically significant (p0.05). After miR-210 diagnosis, COPD sensitivity was 85.6%, the specificity was 72.6%, accuracy (AUC) was 0.821, and 95% CI 0.632-0.924.The down-regulation of MiR-210 expression in the COPD combined with ischemic stroke can be regarded as a sensitive index in diagnosis of COPD and ischemic stroke.
Published: 2016

36. Phase 1 dose-escalating study to evaluate the safety, pharmacokinetics, and pharmacodynamics of a recombinant factor Xa variant (FXa

Author: D, Parsons-Rich, F, Hua, G, Li, C, Kantaridis, D D, Pittman, and S, Arkin
Subjects: Adult, Male, Adolescent, Coagulants, Metabolic Clearance Rate, Antithrombin III, Antibodies, Healthy Volunteers, Peptide Fragments, Recombinant Proteins, Fibrin Fibrinogen Degradation Products, Young Adult, Double-Blind Method, Area Under Curve, Factor Xa, Injections, Intravenous, Prothrombin Time, Humans, Partial Thromboplastin Time, Prothrombin, Blood Coagulation, Biomarkers, Half-Life, Peptide Hydrolases
Abstract: Essentials FXaBackground FXa
Published: 2016

37. Capturing relativistic wakefield structures in plasmas using ultrashort high-energy electrons as a probe

Author: C. J. Zhang, Y. Wan, W. B. Mori, J. F. Hua, Y. Q. Gu, C.-H. Pai, X. L. Xu, C. Joshi, W. Lu, Y. P. Wu, and F. Li
Subjects: Physics, Multidisciplinary, 010308 nuclear & particles physics, FOS: Physical sciences, Plasma, Electron, Wake, Laser, 7. Clean energy, 01 natural sciences, Article, Physics - Plasma Physics, Computational physics, law.invention, Plasma Physics (physics.plasm-ph), Nonlinear system, Physics::Plasma Physics, law, Electric field, 0103 physical sciences, Femtosecond, Physics::Accelerator Physics, 010306 general physics, Charged particle beam
Abstract: A new method capable of capturing coherent electric field structures propagating at nearly the speed of light in plasma with a time resolution as small as a few femtoseconds is proposed. This method uses a few femtoseconds long relativistic electron bunch to probe the wake produced in a plasma by an intense laser pulse or an ultra-short relativistic charged particle beam. As the probe bunch traverses the wake, its momentum is modulated by the electric field of the wake, leading to a density variation of the probe after free-space propagation. This variation of probe density produces a snapshot of the wake that can directly give many useful information of the wake structure and its evolution. Furthermore, this snapshot allows detailed mapping of the longitudinal and transverse components of the wakefield. We develop a theoretical model for field reconstruction and verify it using 3-dimensional particle-in-cell (PIC) simulations. This model can accurately reconstruct the wakefield structure in the linear regime, and it can also qualitatively map the major features of nonlinear wakes. The capturing of the injection in a nonlinear wake is demonstrated through 3D PIC simulations as an example of the applications of this new method., Comment: 9 pages, 6 figures
Published: 2016
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38. [Massive hemorrhage caused by fungal infections after donation-after-cardiac-death kidney transplantation: clinical features, prevention and treatment experience]

Author: D D, Zhao, Z Y, Huang, L Q, Hong, T, Liao, Y E, Tang, N, Na, H, Li, B, Miao, X F, Hua, and Q Q, Sun
Subjects: Antifungal Agents, Heart Diseases, Hemorrhage, Kidney, Kidney Transplantation, Nephrectomy, Tissue Donors, Echinocandins, Lipopeptides, Postoperative Complications, Renal Artery, Treatment Outcome, Mycoses, Micafungin, Humans, Retrospective Studies
Abstract: To study the characteristics and prevention and treatment strategies of massive hemorrhage caused by fungal infections after donation-after-cardiac-death (DCD) kidney transplantation.A total of 91 cases of DCD kidney transplantation between August 25, 2013 and June 30, 2015 in Third Affiliated Hospital of Sun Yat-sen Univservity were retrospectively analyzed. The characteristics of and prevention and treatments strategies for postoperative massive hemorrhage caused by fungal infections were summarized.Ninety-one cases of DCD kidney transplantation were divided into 2 groups based on regimens for preventing postoperative fungal infections: fluconazole prophylaxis group: a total of 26 cases of renal transplant before June 11, 2014 received fluconazole regimen, from postoperative day 0 to 2 weeks; micafungin prophylaxis group: a total of 65 cases of renal transplant after June 11, 2014 received micafungin regimen, also for 2 weeks from postoperative day 0. Two cases in fluconazole group developed postoperative massive hemorrhage. In case 1, the hemorrhage occurred at 2 weeks after transplantation. Graft nephrectomy was performed during surgical exploration for hemostasis, yet the massive hemorrhage relapsed 2 weeks later. Endoluminal exclusion of external iliac artery using endovascular covered stent-graft at the anastomosis site was performed and the massive bleeding was successfully stopped. The patient was restored to hemodialysis and waited for second kidney transplantation. Candia albicans was detected in the culture of blood and drainage liquid from incision. The other case of hemorrhage occurred at 3 weeks after transplantation. Graft nephrectomy plus endovascular exclusion using covered stent-graft were also performed to stop the massive bleeding. Massive fungal hyphae and spores were observed at the stump of renal graft artery under microscope. The patient received second kidney transplantation after 6 months successfully. No massive hemorrhage caused by fungal infections occurred in micafungin prophylaxis group.Massive hemorrhage cased by fungal infections after DCD kidney transplantation is usually characterized by delayed and recurrent course, and may result in graft nephrectomy or even death of patients. Endovascular exclusion using covered stent can successfully stop bleeding and rescue life of patients. Two-week preemptive prophylaxis of fungal infections using micafungin can effectively prevent delayed fungal massive hemorrhage in DCD kidney transplantation.
Published: 2016

39. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Author: Klionsky, D.J. Abdelmohsen, K. Abe, A. Abedin, M.J. Abeliovich, H. Arozena, A.A. Adachi, H. Adams, C.M. Adams, P.D. Adeli, K. Adhihetty, P.J. Adler, S.G. Agam, G. Agarwal, R. Aghi, M.K. Agnello, M. Agostinis, P. Aguilar, P.V. Aguirre-Ghiso, J. Airoldi, E.M. Ait-Si-Ali, S. Akematsu, T. Akporiaye, E.T. Al-Rubeai, M. Albaiceta, G.M. Albanese, C. Albani, D. Albert, M.L. Aldudo, J. Algül, H. Alirezaei, M. Alloza, I. Almasan, A. Almonte-Beceril, M. Alnemri, E.S. Alonso, C. Altan-Bonnet, N. Altieri, D.C. Alvarez, S. Alvarez-Erviti, L. Alves, S. Amadoro, G. Amano, A. Amantini, C. Ambrosio, S. Amelio, I. Amer, A.O. Amessou, M. Amon, A. An, Z. Anania, F.A. Andersen, S.U. Andley, U.P. Andreadi, C.K. Andrieu-Abadie, N. Anel, A. Ann, D.K. Anoopkumar-Dukie, S. Antonioli, M. Aoki, H. Apostolova, N. Aquila, S. Aquilano, K. Araki, K. Arama, E. Aranda, A. Araya, J. Arcaro, A. Arias, E. Arimoto, H. Ariosa, A.R. Armstrong, J.L. Arnould, T. Arsov, I. Asanuma, K. Askanas, V. Asselin, E. Atarashi, R. Atherton, S.S. Atkin, J.D. Attardi, L.D. Auberger, P. Auburger, G. Aurelian, L. Autelli, R. Avagliano, L. Avantaggiati, M.L. Avrahami, L. Azad, N. Awale, S. Bachetti, T. Backer, J.M. Bae, D.-H. Bae, J.-S. Bae, O.-N. Bae, S.H. Baehrecke, E.H. Baek, S.-H. Baghdiguian, S. Bagniewska-Zadworna, A. Bai, H. Bai, J. Bai, X.-Y. Bailly, Y. Balaji, K.N. Balduini, W. Ballabio, A. Balzan, R. Banerjee, R. Bánhegyi, G. Bao, H. Barbeau, B. Barrachina, M.D. Barreiro, E. Bartel, B. Bartolomé, A. Bassham, D.C. Bassi, M.T. Bast, R.C., Jr. Basu, A. Batista, M.T. Batoko, H. Battino, M. Bauckman, K. Baumgarner, B.L. Bayer, K.U. Beale, R. Beaulieu, J.-F. Beck, G.R., Jr. Becker, C. Beckham, J.D. Bédard, P.-A. Bednarski, P.J. Begley, T.J. Behl, C. Behrends, C. Behrens, G.M.N. Behrns, K.E. Bejarano, E. Belaid, A. Belleudi, F. Bénard, G. Berchem, G. Bergamaschi, D. Bergami, M. Berkhout, B. Berliocchi, L. Bernard, A. Bernard, M. Bernassola, F. Bertolotti, A. Bess, A.S. Besteiro, S. Bettuzzi, S. Bhalla, S. Bhattacharyya, S. Bhutia, S.K. Biagosch, C. Bianchi, M.W. Biard-Piechaczyk, M. Billes, V. Bincoletto, C. Bingol, B. Bird, S.W. Bitoun, M. Bjedov, I. Blackstone, C. Blanc, L. Blanco, G.A. Blomhoff, H.K. Boada-Romero, E. Böckler, S. Boes, M. Boesze-Battaglia, K. Boise, L.H. Bolino, A. Boman, A. Bonaldo, P. Bordi, M. Bosch, J. Botana, L.M. Botti, J. Bou, G. Bouché, M. Bouchecareilh, M. Boucher, M.-J. Boulton, M.E. Bouret, S.G. Boya, P. Boyer-Guittaut, M. Bozhkov, P.V. Brady, N. Braga, V.M.M. Brancolini, C. Braus, G.H. Bravo-San-Pedro, J.M. Brennan, L.A. Bresnick, E.H. Brest, P. Bridges, D. Bringer, M.-A. Brini, M. Brito, G.C. Brodin, B. Brookes, P.S. Brown, E.J. Brown, K. Broxmeyer, H.E. Bruhat, A. Brum, P.C. Brumell, J.H. Brunetti-Pierri, N. Bryson-Richardson, R.J. Buch, S. Buchan, A.M. Budak, H. Bulavin, D.V. Bultman, S.J. Bultynck, G. Bumbasirevic, V. Burelle, Y. Burke, R.E. Burmeister, M. Bütikofer, P. Caberlotto, L. Cadwell, K. Cahova, M. Cai, D. Cai, J. Cai, Q. Calatayud, S. Camougrand, N. Campanella, M. Campbell, G.R. Campbell, M. Campello, S. Candau, R. Caniggia, I. Cantoni, L. Cao, L. Caplan, A.B. Caraglia, M. Cardinali, C. Cardoso, S.M. Carew, J.S. Carleton, L.A. Carlin, C.R. Carloni, S. Carlsson, S.R. Carmona-Gutierrez, D. Carneiro, L.A.M. Carnevali, O. Carra, S. Carrier, A. Carroll, B. Casas, C. Casas, J. Cassinelli, G. Castets, P. Castro-Obregon, S. Cavallini, G. Ceccherini, I. Cecconi, F. Cederbaum, A.I. Ceña, V. Cenci, S. Cerella, C. Cervia, D. Cetrullo, S. Chaachouay, H. Chae, H.-J. Chagin, A.S. Chai, C.-Y. Chakrabarti, G. Chamilos, G. Chan, E.Y.W. Chan, M.T.V. Chandra, D. Chandra, P. Chang, C.-P. Chang, R.C.-C. Chang, T.Y. Chatham, J.C. Chatterjee, S. Chauhan, S. Che, Y. Cheetham, M.E. Cheluvappa, R. Chen, C.-J. Chen, G. Chen, G.-C. Chen, G. Chen, H. Chen, J.W. Chen, J.-K. Chen, M. Chen, M. Chen, P. Chen, Q. Chen, Q. Chen, S.-D. Chen, S. Chen, S.S.-L. Chen, W. Chen, W.-J. Chen, W.Q. Chen, W. Chen, X. Chen, Y.-H. Chen, Y.-G. Chen, Y. Chen, Y. Chen, Y. Chen, Y.-J. Chen, Y.-Q. Chen, Y. Chen, Z. Chen, Z. Cheng, A. Cheng, C.H.K. Cheng, H. Cheong, H. Cherry, S. Chesney, J. Cheung, C.H.A. Chevet, E. Chi, H.C. Chi, S.-G. Chiacchiera, F. Chiang, H.-L. Chiarelli, R. Chiariello, M. Chieppa, M. Chin, L.-S. Chiong, M. Chiu, G.N.C. Cho, D.-H. Cho, S.-G. Cho, W.C. Cho, Y.-Y. Cho, Y.-S. Choi, A.M.K. Choi, E.-J. Choi, E.-K. Choi, J. Choi, M.E. Choi, S.-I. Chou, T.-F. Chouaib, S. Choubey, D. Choubey, V. Chow, K.-C. Chowdhury, K. Chu, C.T. Chuang, T.-H. Chun, T. Chung, H. Chung, T. Chung, Y.-L. Chwae, Y.-J. Cianfanelli, V. Ciarcia, R. Ciechomska, I.A. Ciriolo, M.R. Cirone, M. Claerhout, S. Clague, M.J. Cl� ria, J. Clarke, P.G.H. Clarke, R. Clementi, E. Cleyrat, C. Cnop, M. Coccia, E.M. Cocco, T. Codogno, P. Coers, J. Cohen, E.E.W. Colecchia, D. Coletto, L. Coll, N.S. Colucci-Guyon, E. Comincini, S. Condello, M. Cook, K.L. Coombs, G.H. Cooper, C.D. Cooper, J.M. Coppens, I. Corasaniti, M.T. Corazzari, M. Corbalan, R. Corcelle-Termeau, E. Cordero, M.D. Corral-Ramos, C. Corti, O. Cossarizza, A. Costelli, P. Costes, S. Cotman, S.L. Coto-Montes, A. Cottet, S. Couve, E. Covey, L.R. Cowart, L.A. Cox, J.S. Coxon, F.P. Coyne, C.B. Cragg, M.S. Craven, R.J. Crepaldi, T. Crespo, J.L. Criollo, A. Crippa, V. Cruz, M.T. Cuervo, A.M. Cuezva, J.M. Cui, T. Cutillas, P.R. Czaja, M.J. Czyzyk-Krzeska, M.F. Dagda, R.K. Dahmen, U. Dai, C. Dai, W. Dai, Y. Dalby, K.N. Valle, L.D. Dalmasso, G. D'amelio, M. Damme, M. Darfeuille-Michaud, A. Dargemont, C. Darley-Usmar, V.M. Dasarathy, S. Dasgupta, B. Dash, S. Dass, C.R. Davey, H.M. Davids, L.M. Dávila, D. Davis, R.J. Dawson, T.M. Dawson, V.L. Daza, P. de Belleroche, J. de Figueiredo, P. de Figueiredo, R.C.B.Q. de la Fuente, J. De Martino, L. De Matteis, A. De Meyer, G.R.Y. De Milito, A. De Santi, M. de Souza, W. De Tata, V. De Zio, D. Debnath, J. Dechant, R. Decuypere, J.-P. Deegan, S. Dehay, B. Del Bello, B. Del Re, D.P. Delage-Mourroux, R. Delbridge, L.M.D. Deldicque, L. Delorme-Axford, E. Deng, Y. Dengjel, J. Denizot, M. Dent, P. Der, C.J. Deretic, V. Derrien, B. Deutsch, E. Devarenne, T.P. Devenish, R.J. Di Bartolomeo, S. Di Daniele, N. Di Domenico, F. Di Nardo, A. Di Paola, S. Di Pietro, A. Di Renzo, L. Di Antonio, A. Díaz-Araya, G. Díaz-Laviada, I. Diaz-Meco, M.T. Diaz-Nido, J. Dickey, C.A. Dickson, R.C. Diederich, M. Digard, P. Dikic, I. Dinesh-Kumar, S.P. Ding, C. Ding, W.-X. Ding, Z. Dini, L. Distler, J.H.W. Diwan, A. Djavaheri-Mergny, M. Dmytruk, K. Dobson, R.C.J. Doetsch, V. Dokladny, K. Dokudovskaya, S. Donadelli, M. Dong, X.C. Dong, X. Dong, Z. Donohue, T.M., Jr. Donohue-Jr, T.M. Doran, K.S. D'orazi, G. Dorn, G.W., II Dosenko, V. Dridi, S. Drucker, L. Du, J. Du, L.-L. Du, L. du Toit, A. Dua, P. Duan, L. Duann, P. Dubey, V.K. Duchen, M.R. Duchosal, M.A. Duez, H. Dugail, I. Dumit, V.I. Duncan, M.C. Dunlop, E.A. Dunn, W.A., Jr. Dupont, N. Dupuis, L. Durán, R.V. Durcan, T.M. Duvezin-Caubet, S. Duvvuri, U. Eapen, V. Ebrahimi-Fakhari, D. Echard, A. Eckhart, L. Edelstein, C.L. Edinger, A.L. Eichinger, L. Eisenberg, T. Eisenberg-Lerner, A. Eissa, N.T. El-Deiry, W.S. El-Khoury, V. Elazar, Z. Eldar-Finkelman, H. Elliott, C.J.H. Emanuele, E. Emmenegger, U. Engedal, N. Engelbrecht, A.-M. Engelender, S. Enserink, J.M. Erdmann, R. Erenpreisa, J. Eri, R. Eriksen, J.L. Erman, A. Escalante, R. Eskelinen, E.-L. Espert, L. Esteban-Martínez, L. Evans, T.J. Fabri, M. Fabrias, G. Fabrizi, C. Facchiano, A. Færgeman, N.J. Faggioni, A. Fairlie, W.D. Fan, C. Fan, D. Fan, J. Fang, S. Fanto, M. Fanzani, A. Farkas, T. Faure, M. Favier, F.B. Fearnhead, H. Federici, M. Fei, E. Felizardo, T.C. Feng, H. Feng, Y. Feng, Y. Ferguson, T.A. Fernández, Á.F. Fernandez-Barrena, M.G. Fernandez-Checa, J.C. Fernández-López, A. Fernandez-Zapico, M.E. Feron, O. Ferraro, E. Ferreira-Halder, C.V. Fesus, L. Feuer, R. Fiesel, F.C. Filippi-Chiela, E.C. Filomeni, G. Fimia, G.M. Fingert, J.H. Finkbeiner, S. Finkel, T. Fiorito, F. Fisher, P.B. Flajolet, M. 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Steegborn, C. Steele, J.W. Stefanis, L. Steffan, J. Stellrecht, C.M. Stenmark, H. Stepkowski, T.M. Stern, S.T. Stevens, C. Stockwell, B.R. Stoka, V. Storchova, Z. Stork, B. Stratoulias, V. Stravopodis, D.J. Strnad, P. Strohecker, A.M. Ström, A.-L. Stromhaug, P. Stulik, J. Su, Y.-X. Su, Z. Subauste, C.S. Subramaniam, S. Sue, C.M. Suh, S.W. Sui, X. Sukseree, S. Sulzer, D. Sun, F.-L. Sun, J. Sun, J. Sun, S.-Y. Sun, Y. Sun, Y. Sun, Y. Sundaramoorthy, V. Sung, J. Suzuki, H. Suzuki, K. Suzuki, N. Suzuki, T. Suzuki, Y.J. Swanson, M.S. Swanton, C. Swärd, K. Swarup, G. Sweeney, S.T. Sylvester, P.W. Szatmari, Z. Szegezdi, E. Szlosarek, P.W. Taegtmeyer, H. Tafani, M. Taillebourg, E. Tait, S.W.G. Takacs-Vellai, K. Takahashi, Y. Takáts, S. Takemura, G. Takigawa, N. Talbot, N.J. Tamagno, E. Tamburini, J. Tan, C.-P. Tan, L. Tan, M.L. Tan, M. Tan, Y.-J. Tanaka, K. Tanaka, M. Tang, D. Tang, D. Tang, G. Tanida, I. Tanji, K. Tannous, B.A. Tapia, J.A. Tasset-Cuevas, I. Tatar, M. Tavassoly, I. 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Vaccaro, M.I. Váchová, L. Vakifahmetoglu-Norberg, H. Valdor, R. Valente, E.M. Vallette, F. Valverde, A.M. Van den Berghe, G. Van Den Bosch, L. van den Brink, G.R. van der Goot, F.G. van der Klei, I.J. van der Laan, L.J.W. van Doorn, W.G. van Egmond, M. van Golen, K.L. Van Kaer, L. Campagne, M.L. Vandenabeele, P. Vandenberghe, W. Vanhorebeek, I. Varela-Nieto, I. Vasconcelos, M.H. Vasko, R. Vavvas, D.G. Vega-Naredo, I. Velasco, G. Velentzas, A.D. Velentzas, P.D. Vellai, T. Vellenga, E. Vendelbo, M.H. Venkatachalam, K. Ventura, N. Ventura, S. Veras, P.S.T. Verdier, M. Vertessy, B.G. Viale, A. Vidal, M. Vieira, H.L.A. Vierstra, R.D. Vigneswaran, N. Vij, N. Vila, M. Villar, M. Villar, V.H. Villarroya, J. Vindis, C. Viola, G. Viscomi, M.T. Vitale, G. Vogl, D.T. Voitsekhovskaja, O.V. von Haefen, C. von Schwarzenberg, K. Voth, D.E. Vouret-Craviari, V. Vuori, K. Vyas, J.M. Waeber, C. Walker, C.L. Walker, M.J. Walter, J. Wan, L. Wan, X. Wang, B. Wang, C. Wang, C.-Y. Wang, C. Wang, C. Wang, C. 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Zhang, J. Zhang, J. Zhang, J.-P. Zhang, L. Zhang, L. Zhang, L. Zhang, M.-Y. Zhang, X. Zhang, X.D. Zhang, Y. Zhang, Y. Zhang, Y. Zhang, Y. Zhang, Y. Zhao, M. Zhao, W.-L. Zhao, X. Zhao, Y.G. Zhao, Y. Zhao, Y. Zhao, Y.-X. Zhao, Z. Zhao, Z.J. Zheng, D. Zheng, X.-L. Zheng, X. Zhivotovsky, B. Zhong, Q. Zhou, G.-Z. Zhou, G. Zhou, H. Zhou, S.-F. Zhou, X.-J. Zhu, H. Zhu, H. Zhu, W.-G. Zhu, W. Zhu, X.-F. Zhu, Y. Zhuang, S.-M. Zhuang, X. Ziparo, E. Zois, C.E. Zoladek, T. Zong, W.-X. Zorzano, A. Zughaier, S.M.
Published: 2016

40. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Author: Klionsky, D.J. Abdelmohsen, K. Abe, A. Abedin, M.J. Abeliovich, H. Arozena, A.A. Adachi, H. Adams, C.M. Adams, P.D. Adeli, K. Adhihetty, P.J. Adler, S.G. Agam, G. Agarwal, R. Aghi, M.K. Agnello, M. Agostinis, P. Aguilar, P.V. Aguirre-Ghiso, J. Airoldi, E.M. Ait-Si-Ali, S. Akematsu, T. Akporiaye, E.T. Al-Rubeai, M. Albaiceta, G.M. Albanese, C. Albani, D. Albert, M.L. Aldudo, J. Algül, H. Alirezaei, M. Alloza, I. Almasan, A. Almonte-Beceril, M. Alnemri, E.S. Alonso, C. Altan-Bonnet, N. Altieri, D.C. Alvarez, S. Alvarez-Erviti, L. Alves, S. Amadoro, G. Amano, A. Amantini, C. Ambrosio, S. Amelio, I. Amer, A.O. Amessou, M. Amon, A. An, Z. Anania, F.A. Andersen, S.U. Andley, U.P. Andreadi, C.K. Andrieu-Abadie, N. Anel, A. Ann, D.K. Anoopkumar-Dukie, S. Antonioli, M. Aoki, H. Apostolova, N. Aquila, S. Aquilano, K. Araki, K. Arama, E. Aranda, A. Araya, J. Arcaro, A. Arias, E. Arimoto, H. Ariosa, A.R. Armstrong, J.L. Arnould, T. Arsov, I. Asanuma, K. Askanas, V. Asselin, E. Atarashi, R. Atherton, S.S. Atkin, J.D. Attardi, L.D. Auberger, P. Auburger, G. Aurelian, L. Autelli, R. Avagliano, L. Avantaggiati, M.L. Avrahami, L. Azad, N. Awale, S. Bachetti, T. Backer, J.M. Bae, D.-H. Bae, J.-S. Bae, O.-N. Bae, S.H. Baehrecke, E.H. Baek, S.-H. Baghdiguian, S. Bagniewska-Zadworna, A. Bai, H. Bai, J. Bai, X.-Y. Bailly, Y. Balaji, K.N. Balduini, W. Ballabio, A. Balzan, R. Banerjee, R. Bánhegyi, G. Bao, H. Barbeau, B. Barrachina, M.D. Barreiro, E. Bartel, B. Bartolomé, A. Bassham, D.C. Bassi, M.T. Bast, R.C., Jr. Basu, A. Batista, M.T. Batoko, H. Battino, M. Bauckman, K. Baumgarner, B.L. Bayer, K.U. Beale, R. Beaulieu, J.-F. Beck, G.R., Jr. Becker, C. Beckham, J.D. Bédard, P.-A. Bednarski, P.J. Begley, T.J. Behl, C. Behrends, C. Behrens, G.M.N. Behrns, K.E. Bejarano, E. Belaid, A. Belleudi, F. Bénard, G. Berchem, G. Bergamaschi, D. Bergami, M. Berkhout, B. Berliocchi, L. Bernard, A. Bernard, M. Bernassola, F. Bertolotti, A. Bess, A.S. Besteiro, S. Bettuzzi, S. Bhalla, S. Bhattacharyya, S. Bhutia, S.K. Biagosch, C. Bianchi, M.W. Biard-Piechaczyk, M. Billes, V. Bincoletto, C. Bingol, B. Bird, S.W. Bitoun, M. Bjedov, I. Blackstone, C. Blanc, L. Blanco, G.A. Blomhoff, H.K. Boada-Romero, E. Böckler, S. Boes, M. Boesze-Battaglia, K. Boise, L.H. Bolino, A. Boman, A. Bonaldo, P. Bordi, M. Bosch, J. Botana, L.M. Botti, J. Bou, G. Bouché, M. Bouchecareilh, M. Boucher, M.-J. Boulton, M.E. Bouret, S.G. Boya, P. Boyer-Guittaut, M. Bozhkov, P.V. Brady, N. Braga, V.M.M. Brancolini, C. Braus, G.H. Bravo-San-Pedro, J.M. Brennan, L.A. Bresnick, E.H. Brest, P. Bridges, D. Bringer, M.-A. Brini, M. Brito, G.C. Brodin, B. Brookes, P.S. Brown, E.J. Brown, K. Broxmeyer, H.E. Bruhat, A. Brum, P.C. Brumell, J.H. Brunetti-Pierri, N. Bryson-Richardson, R.J. Buch, S. Buchan, A.M. Budak, H. Bulavin, D.V. Bultman, S.J. Bultynck, G. Bumbasirevic, V. Burelle, Y. Burke, R.E. Burmeister, M. Bütikofer, P. Caberlotto, L. Cadwell, K. Cahova, M. Cai, D. Cai, J. Cai, Q. Calatayud, S. Camougrand, N. Campanella, M. Campbell, G.R. Campbell, M. Campello, S. Candau, R. Caniggia, I. Cantoni, L. Cao, L. Caplan, A.B. Caraglia, M. Cardinali, C. Cardoso, S.M. Carew, J.S. Carleton, L.A. Carlin, C.R. Carloni, S. Carlsson, S.R. Carmona-Gutierrez, D. Carneiro, L.A.M. Carnevali, O. Carra, S. Carrier, A. Carroll, B. Casas, C. Casas, J. Cassinelli, G. Castets, P. Castro-Obregon, S. Cavallini, G. Ceccherini, I. Cecconi, F. Cederbaum, A.I. Ceña, V. Cenci, S. Cerella, C. Cervia, D. Cetrullo, S. Chaachouay, H. Chae, H.-J. Chagin, A.S. Chai, C.-Y. Chakrabarti, G. Chamilos, G. Chan, E.Y.W. Chan, M.T.V. Chandra, D. Chandra, P. Chang, C.-P. Chang, R.C.-C. Chang, T.Y. Chatham, J.C. Chatterjee, S. Chauhan, S. Che, Y. Cheetham, M.E. Cheluvappa, R. Chen, C.-J. Chen, G. Chen, G.-C. Chen, G. Chen, H. Chen, J.W. Chen, J.-K. Chen, M. Chen, M. Chen, P. Chen, Q. Chen, Q. Chen, S.-D. Chen, S. Chen, S.S.-L. Chen, W. Chen, W.-J. Chen, W.Q. Chen, W. Chen, X. Chen, Y.-H. Chen, Y.-G. Chen, Y. Chen, Y. Chen, Y. Chen, Y.-J. Chen, Y.-Q. Chen, Y. Chen, Z. Chen, Z. Cheng, A. Cheng, C.H.K. Cheng, H. Cheong, H. Cherry, S. Chesney, J. Cheung, C.H.A. Chevet, E. Chi, H.C. Chi, S.-G. Chiacchiera, F. Chiang, H.-L. Chiarelli, R. Chiariello, M. Chieppa, M. Chin, L.-S. Chiong, M. Chiu, G.N.C. Cho, D.-H. Cho, S.-G. Cho, W.C. Cho, Y.-Y. Cho, Y.-S. Choi, A.M.K. Choi, E.-J. Choi, E.-K. Choi, J. Choi, M.E. Choi, S.-I. Chou, T.-F. Chouaib, S. Choubey, D. Choubey, V. Chow, K.-C. Chowdhury, K. Chu, C.T. Chuang, T.-H. Chun, T. Chung, H. Chung, T. Chung, Y.-L. Chwae, Y.-J. Cianfanelli, V. Ciarcia, R. Ciechomska, I.A. Ciriolo, M.R. Cirone, M. Claerhout, S. Clague, M.J. Clària, J. Clarke, P.G.H. Clarke, R. Clementi, E. Cleyrat, C. Cnop, M. Coccia, E.M. Cocco, T. Codogno, P. Coers, J. Cohen, E.E.W. Colecchia, D. Coletto, L. Coll, N.S. Colucci-Guyon, E. Comincini, S. Condello, M. Cook, K.L. Coombs, G.H. Cooper, C.D. Cooper, J.M. Coppens, I. Corasaniti, M.T. Corazzari, M. Corbalan, R. 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Roelofs, J. Rogov, V.V. Rohn, T.T. Rohrer, B. Romanelli, D. Romani, L. Romano, P.S. Roncero, M.I.G. Rosa, J.L. Rosello, A. Rosen, K.V. Rosenstiel, P. Rost-Roszkowska, M. Roth, K.A. Roué, G. Rouis, M. Rouschop, K.M. Ruan, D.T. Ruano, D. Rubinsztein, D.C. Rucker, E.B., III Rudich, A. Rudolf, E. Rudolf, R. Ruegg, M.A. Ruiz-Roldan, C. Ruparelia, A.A. Rusmini, P. Russ, D.W. Russo, G.L. Russo, G. Russo, R. Rusten, T.E. Ryabovol, V. Ryan, K.M. Ryter, S.W. Sabatini, D.M. Sacher, M. Sachse, C. Sack, M.N. Sadoshima, J. Saftig, P. Sagi-Eisenberg, R. Sahni, S. Saikumar, P. Saito, T. Saitoh, T. Sakakura, K. Sakoh-Nakatogawa, M. Sakuraba, Y. Salazar-Roa, M. Salomoni, P. Saluja, A.K. Salvaterra, P.M. Salvioli, R. Samali, A. Sanchez, A.M.J. Sánchez-Alcázar, J.A. Sanchez-Prieto, R. Sandri, M. Sanjuan, M.A. Santaguida, S. Santambrogio, L. Santoni, G. Dos Santos, C.N. Saran, S. Sardiello, M. Sargent, G. Sarkar, P. Sarkar, S. Sarrias, M.R. Sarwal, M.M. Sasakawa, C. Sasaki, M. Sass, M. Sato, K. Sato, M. Satriano, J. Savaraj, N. Saveljeva, S. Schaefer, L. Schaible, U.E. Scharl, M. Schatzl, H.M. Schekman, R. Scheper, W. Schiavi, A. Schipper, H.M. Schmeisser, H. Schmidt, J. Schmitz, I. Schneider, B.E. Schneider, E.M. Schneider, J.L. Schon, E.A. Schönenberger, M.J. Schönthal, A.H. Schorderet, D.F. Schröder, B. Schuck, S. Schulze, R.J. Schwarten, M. Schwarz, T.L. Sciarretta, S. Scotto, K. Scovassi, A.I. Screaton, R.A. Screen, M. Seca, H. Sedej, S. Segatori, L. Segev, N. Seglen, P.O. Seguí-Simarro, J.M. Segura-Aguilar, J. Seiliez, I. Seki, E. Sell, C. Semenkovich, C.F. Semenza, G.L. Sen, U. Serra, A.L. Serrano-Puebla, A. Sesaki, H. Setoguchi, T. Settembre, C. Shacka, J.J. Shajahan-Haq, A.N. Shapiro, I.M. Sharma, S. She, H. Shen, C.-K.J. Shen, C.-C. Shen, H.-M. Shen, S. Shen, W. Sheng, R. Sheng, X. Sheng, Z.-H. Shepherd, T.G. Shi, J. Shi, Q. Shi, Q. Shi, Y. Shibutani, S. Shibuya, K. Shidoji, Y. Shieh, J.-J. Shih, C.-M. Shimada, Y. Shimizu, S. Shin, D.W. Shinohara, M.L. Shintani, M. Shintani, T. Shioi, T. Shirabe, K. Shiri-Sverdlov, R. Shirihai, O. Shore, G.C. Shu, C.-W. Shukla, D. Sibirny, A.A. Sica, V. Sigurdson, C.J. Sigurdsson, E.M. Sijwali, P.S. Sikorska, B. Silveira, W.A. Silvente-Poirot, S. Silverman, G.A. Simak, J. Simmet, T. Simon, A.K. Simon, H.-U. Simone, C. Simons, M. Simonsen, A. Singh, R. Singh, S.V. Singh, S.K. Sinha, D. Sinha, S. Sinicrope, F.A. Sirko, A. Sirohi, K. Sishi, B.J.N. Sittler, A. Siu, P.M. Sivridis, E. Skwarska, A. Slack, R. Slaninová, I. Slavov, N. Smaili, S.S. Smalley, K.S.M. Smith, D.R. Soenen, S.J. Soleimanpour, S.A. Solhaug, A. Somasundaram, K. Son, J.H. Sonawane, A. Song, C. Song, F. Song, H.K. Song, J.-X. Song, W. Soo, K.Y. Sood, A.K. Soong, T.W. Soontornniyomkij, V. Sorice, M. Sotgia, F. Soto-Pantoja, D.R. Sotthibundhu, A. Sousa, M.J. Spaink, H.P. Span, P.N. Spang, A. Sparks, J.D. Speck, P.G. Spector, S.A. Spies, C.D. Springer, W. Clair, D.S. Stacchiotti, A. Staels, B. Stang, M.T. Starczynowski, D.T. Starokadomskyy, P. Steegborn, C. Steele, J.W. Stefanis, L. Steffan, J. Stellrecht, C.M. Stenmark, H. Stepkowski, T.M. Stern, S.T. Stevens, C. Stockwell, B.R. Stoka, V. Storchova, Z. Stork, B. Stratoulias, V. Stravopodis, D.J. Strnad, P. Strohecker, A.M. Ström, A.-L. Stromhaug, P. Stulik, J. Su, Y.-X. Su, Z. Subauste, C.S. Subramaniam, S. Sue, C.M. Suh, S.W. Sui, X. Sukseree, S. Sulzer, D. Sun, F.-L. Sun, J. Sun, J. Sun, S.-Y. Sun, Y. Sun, Y. Sun, Y. Sundaramoorthy, V. Sung, J. Suzuki, H. Suzuki, K. Suzuki, N. Suzuki, T. Suzuki, Y.J. Swanson, M.S. Swanton, C. Swärd, K. Swarup, G. Sweeney, S.T. Sylvester, P.W. Szatmari, Z. Szegezdi, E. Szlosarek, P.W. Taegtmeyer, H. Tafani, M. Taillebourg, E. Tait, S.W.G. Takacs-Vellai, K. Takahashi, Y. Takáts, S. Takemura, G. Takigawa, N. Talbot, N.J. Tamagno, E. Tamburini, J. Tan, C.-P. Tan, L. Tan, M.L. Tan, M. Tan, Y.-J. Tanaka, K. Tanaka, M. Tang, D. Tang, D. Tang, G. Tanida, I. Tanji, K. Tannous, B.A. Tapia, J.A. Tasset-Cuevas, I. Tatar, M. Tavassoly, I. Tavernarakis, N. Taylor, A. Taylor, G.S. Taylor, G.A. Taylor, J.P. Taylor, M.J. Tchetina, E.V. Tee, A.R. Teixeira-Clerc, F. Telang, S. Tencomnao, T. Teng, B.-B. Teng, R.-J. Terro, F. Tettamanti, G. Theiss, A.L. Theron, A.E. Thomas, K.J. Thomé, M.P. Thomes, P.G. Thorburn, A. Thorner, J. Thum, T. Thumm, M. Thurston, T.L.M. Tian, L. Till, A. Ting, J.P.-Y. Ting, J.P.Y. Titorenko, V.I. Toker, L. Toldo, S. Tooze, S.A. Topisirovic, I. Torgersen, M.L. Torosantucci, L. Torriglia, A. Torrisi, M.R. Tournier, C. Towns, R. Trajkovic, V. Travassos, L.H. Triola, G. Tripathi, D.N. Trisciuoglio, D. Troncoso, R. Trougakos, I.P. Truttmann, A.C. Tsai, K.-J. Tschan, M.P. Tseng, Y.-H. Tsukuba, T. Tsung, A. Tsvetkov, A.S. Tu, S. Tuan, H.-Y. Tucci, M. Tumbarello, D.A. Turk, B. Turk, V. Turner, R.F.B. Tveita, A.A. Tyagi, S.C. Ubukata, M. Uchiyama, Y. Udelnow, A. Ueno, T. Umekawa, M. Umemiya-Shirafuji, R. Underwood, B.R. Ungermann, C. Ureshino, R.P. Ushioda, R. Uversky, V.N. Uzcátegui, N.L. Vaccari, T. Vaccaro, M.I. Váchová, L. Vakifahmetoglu-Norberg, H. Valdor, R. Valente, E.M. Vallette, F. Valverde, A.M. Van den Berghe, G. Van Den Bosch, L. van den Brink, G.R. van der Goot, F.G. van der Klei, I.J. van der Laan, L.J.W. van Doorn, W.G. van Egmond, M. van Golen, K.L. Van Kaer, L. Campagne, M.L. Vandenabeele, P. Vandenberghe, W. Vanhorebeek, I. Varela-Nieto, I. Vasconcelos, M.H. Vasko, R. Vavvas, D.G. Vega-Naredo, I. Velasco, G. Velentzas, A.D. Velentzas, P.D. Vellai, T. Vellenga, E. Vendelbo, M.H. Venkatachalam, K. Ventura, N. Ventura, S. Veras, P.S.T. Verdier, M. Vertessy, B.G. Viale, A. Vidal, M. Vieira, H.L.A. Vierstra, R.D. Vigneswaran, N. Vij, N. Vila, M. Villar, M. Villar, V.H. Villarroya, J. Vindis, C. Viola, G. Viscomi, M.T. Vitale, G. Vogl, D.T. Voitsekhovskaja, O.V. von Haefen, C. von Schwarzenberg, K. Voth, D.E. Vouret-Craviari, V. Vuori, K. Vyas, J.M. Waeber, C. Walker, C.L. Walker, M.J. Walter, J. Wan, L. Wan, X. Wang, B. Wang, C. Wang, C.-Y. Wang, C. Wang, C. Wang, C. Wang, D. Wang, F. Wang, F. Wang, G. Wang, H.-J. Wang, H. Wang, H.-G. Wang, H. Wang, H.-D. Wang, J. Wang, J. Wang, M. Wang, M.-Q. Wang, P.-Y. Wang, P. Wang, R.C. Wang, S. Wang, T.-F. Wang, X. Wang, X.-J. Wang, X.-W. Wang, X. Wang, X. Wang, Y. Wang, Y. Wang, Y. Wang, Y.-J. Wang, Y. Wang, Y. Wang, Y.T. Wang, Y. Wang, Z.-N. Wappner, P. Ward, C. Ward, D.M.V. Warnes, G. Watada, H. Watanabe, Y. Watase, K. Weaver, T.E. Weekes, C.D. Wei, J. Weide, T. Weihl, C.C. Weindl, G. Weis, S.N. Wen, L. Wen, X. Wen, Y. Westermann, B. Weyand, C.M. White, A.R. White, E. Whitton, J.L. Whitworth, A.J. Wiels, J. Wild, F. Wildenberg, M.E. Wileman, T. Wilkinson, D.S. Wilkinson, S. Willbold, D. Williams, C. Williams, K. Williamson, P.R. Winklhofer, K.F. Witkin, S.S. Wohlgemuth, S.E. Wollert, T. Wolvetang, E.J. Wong, E. Wong, G.W. Wong, R.W. Wong, V.K.W. Woodcock, E.A. Wright, K.L. Wu, C. Wu, D. Wu, G.S. Wu, J. Wu, J. Wu, M. Wu, M. Wu, S. Wu, W.K.K. Wu, Y. Wu, Z. Xavier, C.P.R. Xavier, R.J. Xia, G.-X. Xia, T. 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Zhang, J. Zhang, J. Zhang, J.-P. Zhang, L. Zhang, L. Zhang, L. Zhang, M.-Y. Zhang, X. Zhang, X.D. Zhang, Y. Zhang, Y. Zhang, Y. Zhang, Y. Zhang, Y. Zhao, M. Zhao, W.-L. Zhao, X. Zhao, Y.G. Zhao, Y. Zhao, Y. Zhao, Y.-X. Zhao, Z. Zhao, Z.J. Zheng, D. Zheng, X.-L. Zheng, X. Zhivotovsky, B. Zhong, Q. Zhou, G.-Z. Zhou, G. Zhou, H. Zhou, S.-F. Zhou, X.-J. Zhu, H. Zhu, H. Zhu, W.-G. Zhu, W. Zhu, X.-F. Zhu, Y. Zhuang, S.-M. Zhuang, X. Ziparo, E. Zois, C.E. Zoladek, T. Zong, W.-X. Zorzano, A. Zughaier, S.M.
Published: 2016

41. Uptake modes of octadecane by Pseudomonas sp. DG17 and synthesis of biosurfactant

Author: F. Hua and Hongqi Wang
Subjects: chemistry.chemical_classification, biology, Chemistry, Pseudomonas, Substrate (chemistry), General Medicine, Biodegradation, biology.organism_classification, Applied Microbiology and Biotechnology, Microbiology, chemistry.chemical_compound, Bioremediation, Hydrocarbon, Membrane, Octadecane, Food science, Bacteria, Biotechnology
Abstract: Aims: In order to gain more insight into the uptake modes of octadecane by bacteria. Methods and Results: A strain that could utilize octadecane well was isolated from crude oil contaminated soil, and named as Pseudomonas sp. DG17 by 16S rDNA analysis. Culture growth result showed that Pseudomonas sp. DG17 grew well in the addition of 200 and 400 mg l−1 of octadecane, which showed that physical contact between substrate and bacteria was important in the substrate biodegradation. Meanwhile, Pseudomonas sp. DG17 produced rhamnolipids biosurfactant that contains 10 congeners, thus causing the surface tension of the culture medium decline and facilitating the contact between hydrocarbon and bacteria. Scanning-electron-microscopy results showed that a disruption of the surface membranes in certain zones was observed in some of the cells grown in 400 mg l−1 octadecane at 176 h compared with the cells in exponential phase at 72 h due to the production of biosurfactant-rhamnolipid. Conclusions: These results indicated the possibility that the direct contact with insoluble octadecane droplets occurred before the contact with pseudosolubilization smaller oil droplets. Significance: This report throws more light on the uptake mechanisms of octadecane by bacteria, and proposes the possibility that role of biosurfactant is to increase the contact between hydrocarbon and bacteria by changing the cell membrane structure which needs studied in depth. Impact of Study: Results of this study are useful in the bioremediation of petroleum polluted soil.
Published: 2011
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42. Changes in soil carbon and nitrogen under long-term cotton plantations in China

Author: F. Hua, W. Kaiyong, L. Huan, T. Ranab, D. Bo, M. A. Hanjrac, and Z. Fenghua
Subjects: Soil test, Agroforestry, Biomass, Sowing, Soil carbon, Crop, Chine, Agronomy, Soil water, Genetics, Soil horizon, Environmental science, Animal Science and Zoology, Agronomy and Crop Science
Abstract: SUMMARYCotton is the dominant crop in the northern Xinjiang oasis of China; it accounts for 0·78 of the total planting area and represents a major contribution to economic development. The objective of the present study is to determine how cotton plantation age affected chemical and microbiological properties of the soil. The time substitution method was used on plantation farmlands, reclaimed from uncultivated land 0, 5, 10, 15 and 20 years ago. A total of 250 soil samples, at depths of 0–200, 200–400, 400–600, 600–800 and 800–1000 mm, were collected from cotton fields in 10 farms of each age category. There were significant differences in soil organic carbon (SOC), total soil nitrogen (TSN), soil available nitrogen (SAN), soil microbial biomass carbon (SMBC) and soil microbial biomass nitrogen (SMBN). There were also differences in the activities of cellulase, invertase and urease between soil layers and plantation ages, and these were most evident in the 200–400 mm layer. The cumulative rates of SOC and SMBC in the 0–1000 mm soil layer at the 5-, 10-, 15- and 20-year sites were 0·89, 0·99, 1·01 and 0·92 mg/kg/yr and 16, 16, 16 and 15 mg/kg/yr, respectively, compared to that at the control site (0 year). The cumulative amounts of SOC and SMBC increased gradually and then decreased, reaching a maximum at plantation ages of 13·1 years and 11·1 years, respectively. This suggests that incorporation of post-harvest cotton residues could be used as an effective measure to improve SOC in farmland of Xinjiang Oasis, and may be recommended for adoption in cotton growing in semi-arid oasis agriculture.
Published: 2011
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43. Low energy event reconstruction in IceCube DeepCore

Author: R. Abbasi, M. Ackermann, J. Adams, J. A. Aguilar, M. Ahlers, M. Ahrens, J. M. Alameddine, A. A. Alves, N. M. Amin, K. Andeen, T. Anderson, G. Anton, C. Argüelles, Y. Ashida, S. Axani, X. Bai, A. Balagopal V., S. W. Barwick, B. Bastian, V. Basu, S. Baur, R. Bay, J. J. Beatty, K.-H. Becker, J. Becker Tjus, J. Beise, C. Bellenghi, S. Benda, S. BenZvi, D. Berley, E. Bernardini, D. Z. Besson, G. Binder, D. Bindig, E. Blaufuss, S. Blot, M. Boddenberg, F. Bontempo, J. Y. Book, J. Borowka, S. Böser, O. Botner, J. Böttcher, E. Bourbeau, F. Bradascio, J. Braun, B. Brinson, S. Bron, J. Brostean-Kaiser, R. T. Burley, R. S. Busse, M. A. Campana, E. G. Carnie-Bronca, C. Chen, Z. Chen, D. Chirkin, K. Choi, B. A. Clark, K. Clark, L. Classen, A. Coleman, G. H. Collin, J. M. Conrad, P. Coppin, P. Correa, D. F. Cowen, R. Cross, C. Dappen, P. Dave, C. De Clercq, J. J. DeLaunay, D. Delgado López, H. Dembinski, K. Deoskar, A. Desai, P. Desiati, K. D. de Vries, G. de Wasseige, M. de With, T. De Young, A. Diaz, J. C. Díaz-Vélez, M. Dittmer, H. Dujmovic, M. Dunkman, M. A. DuVernois, T. Ehrhardt, P. Eller, R. Engel, H. Erpenbeck, J. Evans, P. A. Evenson, K. L. Fan, A. R. Fazely, A. Fedynitch, N. Feigl, S. Fiedlschuster, A. T. Fienberg, C. Finley, L. Fischer, D. Fox, A. Franckowiak, E. Friedman, A. Fritz, P. Fürst, T. K. Gaisser, J. Gallagher, E. Ganster, A. Garcia, S. Garrappa, L. Gerhardt, A. Ghadimi, C. Glaser, T. Glauch, T. Glüsenkamp, N. Goehlke, J. G. Gonzalez, S. Goswami, D. Grant, T. Grégoire, S. Griswold, C. Günther, P. Gutjahr, C. Haack, A. Hallgren, R. Halliday, L. Halve, F. Halzen, M. Ha Minh, K. Hanson, J. Hardin, A. A. Harnisch, A. Haungs, D. Hebecker, K. Helbing, F. Henningsen, E. C. Hettinger, S. Hickford, J. Hignight, C. Hill, G. C. Hill, K. D. Hoffman, R. Hoffmann, K. Hoshina, W. Hou, F. Huang, M. Huber, T. Huber, K. Hultqvist, M. Hünnefeld, R. Hussain, K. Hymon, S. In, N. Iovine, A. Ishihara, M. Jansson, G. S. Japaridze, M. Jeong, M. Jin, B. J. P. Jones, D. Kang, W. Kang, X. Kang, A. Kappes, D. Kappesser, L. Kardum, T. Karg, M. Karl, A. Karle, U. Katz, M. Kauer, M. Kellermann, J. L. Kelley, A. Kheirandish, K. Kin, T. Kintscher, J. Kiryluk, S. R. Klein, A. Kochocki, R. Koirala, H. Kolanoski, T. Kontrimas, L. Köpke, C. Kopper, S. Kopper, D. J. Koskinen, P. Koundal, M. Kovacevich, M. Kowalski, T. Kozynets, E. Krupczak, E. Kun, N. Kurahashi, N. Lad, C. Lagunas Gualda, J. L. Lanfranchi, M. J. Larson, F. Lauber, J. P. Lazar, J. W. Lee, K. Leonard, A. Leszczynska, Y. Li, M. Lincetto, Q. R. Liu, M. Liubarska, E. Lohfink, C. J. Lozano Mariscal, L. Lu, F. Lucarelli, A. Ludwig, W. Luszczak, Y. Lyu, W. Y. Ma, J. Madsen, K. B. M. Mahn, Y. Makino, S. Mancina, I. C. Maris, I. Martinez-Soler, R. Maruyama, S. McCarthy, T. McElroy, F. McNally, J. V. Mead, K. Meagher, S. Mechbal, A. Medina, M. Meier, S. Meighen-Berger, J. Micallef, D. Mockler, T. Montaruli, R. W. Moore, R. Morse, M. Moulai, T. Mukherjee, R. Naab, R. Nagai, U. Naumann, J. Necker, L. V. Nguyễn, H. Niederhausen, M. U. Nisa, S. C. Nowicki, A. Obertacke Pollmann, M. Oehler, B. Oeyen, A. Olivas, E. O’Sullivan, H. Pandya, D. V. Pankova, N. Park, G. K. Parker, E. N. Paudel, L. Paul, C. Pérez de los Heros, L. Peters, J. Peterson, S. Philippen, S. Pieper, A. Pizzuto, M. Plum, Y. Popovych, A. Porcelli, M. Prado Rodriguez, B. Pries, G. T. Przybylski, C. Raab, J. Rack-Helleis, A. Raissi, M. Rameez, K. Rawlins, I. C. Rea, Z. Rechav, A. Rehman, P. Reichherzer, R. Reimann, G. Renzi, E. Resconi, S. Reusch, W. Rhode, M. Richman, B. Riedel, E. J. Roberts, S. Robertson, G. Roellinghoff, M. Rongen, C. Rott, T. Ruhe, D. Ryckbosch, D. Rysewyk Cantu, I. Safa, J. Saffer, P. Sampathkumar, S. E. Sanchez Herrera, A. Sandrock, M. Santander, S. Sarkar, K. Satalecka, M. Schaufel, H. Schieler, S. Schindler, T. Schmidt, A. Schneider, J. Schneider, F. G. Schröder, L. Schumacher, G. Schwefer, S. Sclafani, D. Seckel, S. Seunarine, A. Sharma, S. Shefali, N. Shimizu, M. Silva, B. Skrzypek, B. Smithers, R. Snihur, J. Soedingrekso, D. Soldin, C. Spannfellner, G. M. Spiczak, C. Spiering, J. Stachurska, M. Stamatikos, T. Stanev, R. Stein, J. Stettner, T. Stezelberger, T. Stürwald, T. Stuttard, G. W. Sullivan, I. Taboada, S. Ter-Antonyan, J. Thwaites, S. Tilav, F. Tischbein, K. Tollefson, C. Tönnis, S. Toscano, D. Tosi, A. Trettin, M. Tselengidou, C. F. Tung, A. Turcati, R. Turcotte, C. F. Turley, J. P. Twagirayezu, B. Ty, M. A. Unland Elorrieta, N. Valtonen-Mattila, J. Vandenbroucke, N. van Eijndhoven, D. Vannerom, J. van Santen, J. Veitch-Michaelis, S. Verpoest, C. Walck, W. Wang, T. B. Watson, C. Weaver, P. Weigel, A. Weindl, M. J. Weiss, J. Weldert, C. Wendt, J. Werthebach, M. Weyrauch, N. Whitehorn, C. H. Wiebusch, N. Willey, D. R. Williams, M. Wolf, G. Wrede, J. Wulff, X. W. Xu, J. P. Yanez, E. Yildizci, S. Yoshida, S. Yu, T. Yuan, Z. Zhang, P. Zhelnin, and IceCube Collaboration
Subjects: Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract: Abstract The reconstruction of event-level information, such as the direction or energy of a neutrino interacting in IceCube DeepCore, is a crucial ingredient to many physics analyses. Algorithms to extract this high level information from the detector’s raw data have been successfully developed and used for high energy events. In this work, we address unique challenges associated with the reconstruction of lower energy events in the range of a few to hundreds of GeV and present two separate, state-of-the-art algorithms. One algorithm focuses on the fast directional reconstruction of events based on unscattered light. The second algorithm is a likelihood-based multipurpose reconstruction offering superior resolutions, at the expense of larger computational cost.
Published: 2022
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44. Large genomic deletion linked to field-evolved resistance to Cry1F corn in fall armyworm (Spodoptera frugiperda) from Florida

Author: R. Banerjee, C. P. De Bortoli, F. Huang, K. Lamour, R. Meagher, D. Buntin, X. Ni, F. P. F. Reay-Jones, S. Stewart, and Juan Luis Jurat-Fuentes
Subjects: Medicine, Science
Abstract: Abstract The fall armyworm (Spodoptera frugiperda) is a highly polyphagous lepidopteran pest of relevant food and fiber staple crops. In the Americas, transgenic corn and cotton producing insecticidal proteins from the bacterium Bacillus thuringiensis (Bt) have controlled and reduced the damage caused by S. frugiperda. However, cases of field-evolved S. frugiperda resistance to Bt corn producing the Cry1F insecticidal protein have been documented in North and South America. When characterized, field resistance to Cry1F is linked to insertions and mutations resulting in a modified or truncated ABC transporter subfamily C2 (SfABCC2) protein that serves as Cry1F receptor in susceptible S. frugiperda. In this work, we present detection of a large genomic deletion (~ 8 kb) affecting the SfABCC2 and an ABC transporter gene subfamily 3 –like gene (SfABCC3) as linked to resistance to Cry1F corn in a S. frugiperda strain from Florida (FL39). Monitoring for this genomic deletion using a discriminatory PCR reaction in field-collected S. frugiperda moths detected individuals carrying this allele in Florida, but not in surrounding states. This is the first report of a large genomic deletion being involved in resistance to a Bt insecticidal protein.
Published: 2022
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45. A global dataset of spatiotemporally seamless daily mean land surface temperatures: generation, validation, and analysis

Author: F. Hong, W. Zhan, F.-M. Göttsche, Z. Liu, P. Dong, H. Fu, F. Huang, and X. Zhang
Subjects: Environmental sciences, GE1-350, Geology, QE1-996.5
Abstract: Daily mean land surface temperatures (LSTs) acquired from polar orbiters are crucial for various applications such as global and regional climate change analysis. However, thermal sensors from polar orbiters can only sample the surface effectively with very limited times per day under cloud-free conditions. These limitations have produced a systematic sampling bias (ΔTsb) on the daily mean LST (Tdm) estimated with the traditional method, which uses the averages of clear-sky LST observations directly as the Tdm. Several methods have been proposed for the estimation of the Tdm, yet they are becoming less capable of generating spatiotemporally seamless Tdm across the globe. Based on MODIS and reanalysis data, here we propose an improved annual and diurnal temperature cycle-based framework (termed the IADTC framework) to generate global spatiotemporally seamless Tdm products ranging from 2003 to 2019 (named the GADTC products). The validations show that the IADTC framework reduces the systematic ΔTsb significantly. When validated only with in situ data, the assessments show that the mean absolute errors (MAEs) of the IADTC framework are 1.4 and 1.1 K for SURFRAD and FLUXNET data, respectively, and the mean biases are both close to zero. Direct comparisons between the GADTC products and in situ measurements indicate that the MAEs are 2.2 and 3.1 K for the SURFRAD and FLUXNET datasets, respectively, and the mean biases are −1.6 and −1.5 K for these two datasets, respectively. By taking the GADTC products as references, further analysis reveals that the Tdm estimated with the traditional averaging method yields a positive systematic ΔTsb of greater than 2.0 K in low-latitude and midlatitude regions while of a relatively small value in high-latitude regions. Although the global-mean LST trend (2003 to 2019) calculated with the traditional method and the IADTC framework is relatively close (both between 0.025 to 0.029 K yr−1), regional discrepancies in LST trend do occur – the pixel-based MAE in LST trend between these two methods reaches 0.012 K yr−1. We consider the IADTC framework can guide the further optimization of Tdm estimation across the globe, and the generated GADTC products should be valuable in various applications such as global and regional warming analysis. The GADTC products are freely available at https://doi.org/10.5281/zenodo.6287052 (Hong et al., 2022).
Published: 2022
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46. Search for non-standard neutrino interactions with 10 years of ANTARES data

Author: The ANTARES collaboration, A. Albert, S. Alves, M. André, M. Anghinolfi, G. Anton, M. Ardid, S. Ardid, J.-J. Aubert, J. Aublin, B. Baret, S. Basa, B. Belhorma, M. Bendahman, F. Benfenati, V. Bertin, S. Biagi, M. Bissinger, J. Boumaaza, M. Bouta, M. C. Bouwhuis, H. Brânzaş, R. Bruijn, J. Brunner, J. Busto, B. Caiffi, D. Calvo, A. Capone, L. Caramete, J. Carr, V. Carretero, S. Celli, M. Chabab, T. N. Chau, R. Cherkaoui El Moursli, T. Chiarusi, M. Circella, A. Coleiro, R. Coniglione, P. Coyle, A. Creusot, A. F. Díaz, G. de Wasseige, C. Distefano, I. Di Palma, A. Domi, C. Donzaud, D. Dornic, D. Drouhin, T. Eberl, T. van Eeden, D. van Eijk, N. El Khayati, A. Enzenhöfer, P. Fermani, G. Ferrara, F. Filippini, L. Fusco, Y. Gatelet, P. Gay, H. Glotin, R. Gozzini, R. Gracia Ruiz, K. Graf, C. Guidi, S. Hallmann, H. van Haren, A. J. Heijboer, Y. Hello, J. J. Hernández-Rey, J. Hößl, J. Hofestädt, F. Huang, G. Illuminati, C. W. James, B. Jisse-Jung, M. de Jong, P. de Jong, M. Kadler, O. Kalekin, U. Katz, N. R. Khan-Chowdhury, A. Kouchner, I. Kreykenbohm, V. Kulikovskiy, R. Lahmann, R. Le Breton, S. LeStum, D. Lefèvre, E. Leonora, G. Levi, M. Lincetto, D. Lopez-Coto, S. Loucatos, L. Maderer, J. Manczak, M. Marcelin, A. Margiotta, A. Marinelli, J. A. Martínez-Mora, B. Martino, K. Melis, P. Migliozzi, A. Moussa, R. Muller, L. Nauta, S. Navas, E. Nezri, B. Ó Fearraigh, A. Păun, G. E. Păvălaş, C. Pellegrino, M. Perrin-Terrin, V. Pestel, P. Piattelli, C. Pieterse, C. Poirè, V. Popa, T. Pradier, N. Randazzo, D. Real, S. Reck, G. Riccobene, A. Romanov, A. Sánchez-Losa, F. Salesa Greus, D. F. E. Samtleben, M. Sanguineti, P. Sapienza, J. Schnabel, J. Schumann, F. Schüssler, J. Seneca, M. Spurio, Th. Stolarczyk, M. Taiuti, Y. Tayalati, T. Thakore, S. J. Tingay, B. Vallage, V. Van Elewyck, F. Versari, S. Viola, D. Vivolo, J. Wilms, S. Zavatarelli, A. Zegarelli, J. D. Zornoza, and J. Zúñiga
Subjects: Neutrino Detectors and Telescopes (experiments), Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract: Abstract Non-standard interactions of neutrinos arising in many theories beyond the Standard Model can significantly alter matter effects in atmospheric neutrino propagation through the Earth. In this paper, a search for deviations from the prediction of the standard 3-flavour atmospheric neutrino oscillations using the data taken by the ANTARES neutrino telescope is presented. Ten years of atmospheric neutrino data collected from 2007 to 2016, with reconstructed energies in the range from ∼16 GeV to 100 GeV, have been analysed. A log-likelihood ratio test of the dimensionless coefficients ε μτ and ε ττ − ε μμ does not provide clear evidence of deviations from standard interactions. For normal neutrino mass ordering, the combined fit of both coefficients yields a value 1.7σ away from the null result. However, the 68% and 95% confidence level intervals for ε μτ and ε ττ − ε μμ , respectively, contain the null value. Best fit values, one standard deviation errors and bounds at the 90% confidence level for these coefficients are given for both normal and inverted mass orderings. The constraint on ε μτ is among the most stringent to date and it further restrains the strength of possible non-standard interactions in the μ − τ sector.
Published: 2022
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47. Effects of fumonisin B1 on HLA class I antigen presentation and processing pathway in GES-1 cells in vitro

Author: Xianghong Zhang, Juan Wang, Junling Wang, Lingxiao Xing, Xia Yan, Xin Xing, ZG Yao, and F. Hua
Subjects: Time Factors, Cell Survival, Health, Toxicology and Mutagenesis, Blotting, Western, Immunocytochemistry, Cell Culture Techniques, Gene Expression, Human leukocyte antigen, Biology, Toxicology, medicine.disease_cause, Fumonisins, Cell Line, Malignant transformation, medicine, Humans, Antigen Presentation, Dose-Response Relationship, Drug, Reverse Transcriptase Polymerase Chain Reaction, Histocompatibility Antigens Class I, Epithelial Cells, General Medicine, Immunohistochemistry, Molecular biology, Carcinogens, Environmental, Immunosurveillance, Blot, Reverse transcription polymerase chain reaction, TAP1, Carcinogenesis
Abstract: Fumonisin B1 (FB1) is a food-borne mycotoxin produced by genus Fusarium and was classified as possible carcinogen to humans by the International Agency for Research on Cancer (IARC). Human leukocyte antigen (HLA) class I antigen presentation pathway plays an important role in immunosurveillance. Defects in HLA class I antigen presentation pathway can down-regulate the expression of HLA class I antigen on the surface of nucleated cells that will confer a survival advantage to randomly mutant cells and may lead to malignant transformation. In the present study, we analyzed the effects of FB1 on the expression of HLA class I heavy chain (classical HLA-A, -B and -C genes included), beta2-microglobulin (β2m), LMP2 and TAP1 genes in human gastric epithelial immortalized GES-1 cells in vitro using semi-quantitative Reverse Transcription Polymerase Chain Reaction (RT-PCR), Western blot and immunocytochemical methods in dose- and time-effect studies. Our results revealed that FB1 have an effect on HLA class I antigen presentation pathway via the decreased expression of HLA class I heavy chain and/or defects of LMP2 and TAP1 expression. However, the importance of this effect in carcinogenesis needs further investigation.
Published: 2010
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48. Electron Acceleration Based on an Elongated Plasma Channel

Author: Sergei V. Bulanov, J. F. Hua, Toshiki Tajima, Yuchi Wu, Yuqiu Gu, Liming Chen, Hideyuki Kotaki, K. Sugiyama, H. S. Peng, Takashi Kameshima, Wei Hong, James Koga, Xianlun Wen, K. Nakajima, C. M. Tang, and Shin-ichi Kurokawa
Subjects: Physics, Nuclear and High Energy Physics, Self-focusing, Plasma, Condensed Matter Physics, Laser, Plasma acceleration, law.invention, Particle acceleration, Physics::Plasma Physics, law, Rayleigh length, Physics::Accelerator Physics, Plasma channel, Atomic physics, Electric current
Abstract: Experiments for the laser guiding studies has been carried out with the 30-fs 100-TW Ti:sapphire laser pulse interaction with the underdense plasma produced by a long-slab (1.2 times 10 mm2) gas jet and an ablative laser-triggered discharged capillary. Formation of an extremely long plasma channel with a length (~10 mm) 10 times above the Rayleigh length is observed when the laser pulse power is much higher than the critical power for relativistic self-focusing. The long-self-guiding- channel formation is accompanied by the electron acceleration with a low transverse emittance (< 0.87pi mm mrad) and high electric current (~10 nC/shot), as well as the generation of a quasi- monoenergetic electron bunch with an energy of ~80 MeV. In order to continuously elongate the plasma channel, a 4-cm- scale discharged capillary was used. We successfully demonstrated laser-plasma acceleration of high-quality electron beams up to nearly semigigaelectronvolts. Our results exactly verified the prediction of laser wakefield acceleration through a centimeter- scale plasma channel in the "blowout bubble" regime, where a microscale plasma cavity produced through the ultrarelativistic laser-plasma interactions plays an essential role in the self- injection and acceleration of electrons.
Published: 2008
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49. Hint for a TeV neutrino emission from the Galactic Ridge with ANTARES

Author: A. Albert, S. Alves, M. André, M. Ardid, S. Ardid, J.-J. Aubert, J. Aublin, B. Baret, S. Basa, Y. Becherini, B. Belhorma, M. Bendahman, F. Benfenati, V. Bertin, S. Biagi, M. Bissinger, J. Boumaaza, M. Bouta, M.C. Bouwhuis, H. Brânzaş, R. Bruijn, J. Brunner, J. Busto, B. Caiffi, D. Calvo, S. Campion, A. Capone, L. Caramete, F. Carenini, J. Carr, V. Carretero, S. Celli, L. Cerisy, M. Chabab, T.N. Chau, R. Cherkaoui El Moursli, T. Chiarusi, M. Circella, J.A.B. Coelho, A. Coleiro, R. Coniglione, P. Coyle, A. Creusot, A.F. Díaz, B. De Martino, C. Distefano, I. Di Palma, A. Domi, C. Donzaud, D. Dornic, D. Drouhin, T. Eberl, T. van Eeden, D. van Eijk, S. El Hedri, N. El Khayati, A. Enzenhöfer, M. Fasano, P. Fermani, G. Ferrara, F. Filippini, L. Fusco, S. Gagliardini, J. García, C. Gatius Oliver, P. Gay, N. Geißelbrecht, H. Glotin, R. Gozzini, R. Gracia Ruiz, K. Graf, C. Guidi, L. Haegel, S. Hallmann, H. van Haren, A.J. Heijboer, Y. Hello, J.J. Hernández-Rey, J. Hößl, J. Hofestädt, F. Huang, G. Illuminati, C.W. James, B. Jisse-Jung, M. de Jong, P. de Jong, M. Kadler, O. Kalekin, U. Katz, A. Kouchner, I. Kreykenbohm, V. Kulikovskiy, R. Lahmann, M. Lamoureux, A. Lazo, D. Lefèvre, E. Leonora, G. Levi, S. Le Stum, D. Lopez-Coto, S. Loucatos, L. Maderer, J. Manczak, M. Marcelin, A. Margiotta, A. Marinelli, J.A. Martínez-Mora, P. Migliozzi, A. Moussa, R. Muller, L. Nauta, S. Navas, A. Neronov, E. Nezri, B. Ó Fearraigh, A. Păun, G.E. Păvălaş, M. Perrin-Terrin, V. Pestel, P. Piattelli, C. Poirè, V. Popa, T. Pradier, N. Randazzo, D. Real, S. Reck, G. Riccobene, A. Romanov, A. Sánchez-Losa, A. Saina, F. Salesa Greus, D.F.E. Samtleben, M. Sanguineti, P. Sapienza, D. Savchenko, J. Schnabel, J. Schumann, F. Schüssler, J. Seneca, M. Spurio, Th. Stolarczyk, M. Taiuti, Y. Tayalati, S.J. Tingay, B. Vallage, G. Vannoye, V. Van Elewyck, S. Viola, D. Vivolo, J. Wilms, S. Zavatarelli, A. Zegarelli, J.D. Zornoza, and J. Zúñiga
Subjects: ANTARES, Neutrino telescope, Galactic Centre, Cosmic ray, Pion-decay model, Physics, QC1-999
Abstract: Interactions of cosmic ray protons, atomic nuclei, and electrons in the interstellar medium in the inner part of the Milky Way produce a γ-ray flux from the Galactic Ridge. If the γ-ray emission is dominated by proton and nuclei interactions, a neutrino flux comparable to the γ-ray flux is expected from the same sky region.Data collected by the ANTARES neutrino telescope are used to constrain the neutrino flux from the Galactic Ridge in the 1-100 TeV energy range. Neutrino events reconstructed both as tracks and showers are considered in the analysis and the selection is optimized for the search of an excess in the region |l|
Published: 2023
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50. Bioassay of enrich-blood bioactivity in the group of Dang gui roots

Author: G Lu, Y Yue, F Hua, X Wang, Xin Li, and B Yang
Subjects: Pharmacology, Complementary and alternative medicine, Traditional medicine, business.industry, Organic Chemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Bioassay, Medicine, business, Analytical Chemistry
Published: 2015
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