Search

Your search keyword '"F. Melot"' showing total 11 results
Start Over Author "F. Melot"
11 results on '"F. Melot"'

1. Cosmic-Ray Database Update: Ultra-High Energy, Ultra-Heavy, and Antinuclei Cosmic-Ray Data (CRDB v4.0)

Author

Ioana Codrina Maris, Hans Peter Dembinski, F. Melot, David Maurin, J. E. Gonzalez, Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), and Université Grenoble Alpes (UGA)

Subjects
lcsh:QC793-793.5, High energy, Ajax, neutron star: binary, 010504 meteorology & atmospheric sciences, nucleus: UHE, databases, WIMP, air, FOS: Physical sciences, General Physics and Astronomy, Cosmic ray, computer.software_genre, 01 natural sciences, KASCADE, astroparticle, cosmic rays, PAMELA, 0103 physical sciences, Web page, quantum chromodynamics, AMS, structure, cosmic radiation: UHE, antinucleus: cosmic radiation, capture, 010303 astronomy & astrophysics, Monte Carlo, 0105 earth and related environmental sciences, computer.programming_language, High Energy Astrophysical Phenomena (astro-ph.HE), Physics, Database, showers: atmosphere, cosmic radiation: spectrum, lcsh:Elementary particle physics, solar, anti-p, TheoryofComputation_MATHEMATICALLOGICANDFORMALLANGUAGES, 13. Climate action, DAMPE, upgrade, data management, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], Astrophysics - High Energy Astrophysical Phenomena, computer, cosmic radiation: flux, Charged species
Abstract

We present an update on CRDB, the cosmic-ray database for charged species. CRDB is based on MySQL, queried and sorted by jquery and table-sorter libraries, and displayed via PHP web pages through the AJAX protocol. We review the modifications made on the structure and outputs of the database since the first release (Maurin et al., 2014). For this update, the most important feature is the inclusion of ultra-heavy nuclei ( Z &gt, 30 ), ultra-high energy nuclei (from 10 15 to 10 20 eV), and limits on antinuclei fluxes ( Z ≤ − 1 for A &gt, 1 ), more than 100 experiments, 350 publications, and 40,000 data points are now available in CRDB. We also revisited and simplified how users can retrieve data and submit new ones. For questions and requests, please contact crdb@lpsc.in2p3.fr.

Published
2020
Full Text
View/download PDF

2. Neutron monitors and muon detectors for solar modulation studies: 2. $\phi$ time series

Author

F. Melot, A. Ghelfi, A. Cheminet, Guillaume Hubert, David Maurin, Laurent Derome, Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Centre National de la Recherche Scientifique (CNRS), ONERA - The French Aerospace Lab [Toulouse], and ONERA

Subjects
Atmospheric Science, Solar modulation, [PHYS.ASTR.HE]Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE], 010504 meteorology & atmospheric sciences, Aerospace Engineering, Cosmic ray, Astrophysics, 01 natural sciences, Nuclear physics, 0103 physical sciences, Modulation (music), Neutron, 010303 astronomy & astrophysics, Cosmic rays, 0105 earth and related environmental sciences, Physics, Neutron monitor, Spectrometer, Series (mathematics), Detector, Astronomy and Astrophysics, [PHYS.PHYS.PHYS-SPACE-PH]Physics [physics]/Physics [physics]/Space Physics [physics.space-ph], Muon detector, Geophysics, Astrophysics - Solar and Stellar Astrophysics, Space and Planetary Science, General Earth and Planetary Sciences, SPHERES, Astrophysics - High Energy Astrophysical Phenomena
Abstract

The level of solar modulation at different times (related to the solar activity) is a central question of solar and galactic cosmic-ray physics. In the first paper of this series, we have established a correspondence between the uncertainties on ground-based detectors count rates and the parameter $\phi$ (modulation level in the force-field approximation) reconstructed from these count rates. In this second paper, we detail a procedure to obtain a reference $\phi$ time series from neutron monitor data. We show that we can have an unbiased and accurate $\phi$ reconstruction ($\Delta\phi/\phi\simeq 10\%$). We also discuss the potential of Bonner spheres spectrometers and muon detectors to provide $\phi$ time series. Two by-products of this calculation are updated $\phi$ values for the cosmic-ray database and a web interface to retrieve and plot $\phi$ from the 50's to today (\url{http://lpsc.in2p3.fr/crdb})., Comment: 15 pages, 5 figures, 2 tables. AdSR, in press. Web interface to get modulation parameter phi(t): new tab in http://lpsc.in2p3.fr/crdb

Published
2016
Full Text
View/download PDF

4. Cryogenic characterization of the Planck sorption cooler system flight model

Author

N. Mandolesi, C. Butler, Marco Bersanelli, Anna Gregorio, P. Stassi, Gianluca Morgante, B. Hernandez, David Pearson, F. Melot, P. Wilson, Luca Terenzi, L. A. Wade, Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS), G., Morgante, D., Pearson, F., Melot, P., Stassi, L., Terenzi, P., Wilson, B., Hernandez, L., Wade, Gregorio, Anna, M., Bersanelli, and C. BUTLER AND N., Mandolesi

Subjects
[PHYS.ASTR.IM]Physics [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM], Refrigerator car, FOS: Physical sciences, Propulsion, 01 natural sciences, 7. Clean energy, Jet propulsion, Cryocoolers, symbols.namesake, Instruments for CMB observations, CMB physics, 0103 physical sciences, Heat exchanger, Aerospace engineering, Planck, 010306 general physics, Instrumentation and Methods for Astrophysics (astro-ph.IM), 010303 astronomy & astrophysics, Instrumentation, Mathematical Physics, Spacecraft, Planck ESA mission, business.industry, Cryogenics and thermal models, Cryocooler, Power (physics), [SDU.ASTR.IM]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM], Space instrumentation, symbols, [PHYS.MECA.THER]Physics [physics]/Mechanics [physics]/Thermics [physics.class-ph], [SPI.MECA.THER]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Thermics [physics.class-ph], Environmental science, Astrophysics - Instrumentation and Methods for Astrophysics, business
Abstract

This paper is part of the Prelaunch status LFI papers published on JINST: http://www.iop.org/EJ/journal/-page=extra.proc5/1748-0221 Two continuous closed-cycle hydrogen Joule-Thomson (J-T) sorption coolers have been fabricated and assembled by the Jet Propulsion Laboratory (JPL) for the European Space Agency (ESA) Planck mission. Each refrigerator has been designed to provide a total of ~ 1W of cooling power at two instrument interfaces: they directly cool the Planck Low Frequency Instrument (LFI) around 20K while providing a pre-cooling stage for a 4 K J-T mechanical refrigerator for the High Frequency Instrument (HFI). After sub-system level validation at JPL, the cryocoolers have been delivered to ESA in 2005. In this paper we present the results of the cryogenic qualification and test campaigns of the Nominal Unit on the flight model spacecraft performed at the CSL (Centre Spatial de Liege) facilities in 2008. Test results in terms of input power, cooling power, temperature, and temperature fluctuations over the flight allowable ranges for these interfaces are reported and analyzed with respect to mission requirements., Comment: This is an author-created, un-copyedited version of an article accepted for publication in Journal of Instrumentation. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The definitive publisher authenticated version is available online at 10.1088/1748-0221/4/12/T12016

Published
2009
Full Text
View/download PDF

5. Isolation of bovine follicular dendritic cells allows the demonstration of a particular cellular prion protein

Author

F. Leclercq, Ernst Heinen, F. Melot, Y. Frobert, Rikiya Tsunoda, Nadine Antoine, Olivier Jolois, and Caroline Thielen

Subjects
Histology, medicine.drug_class, animal diseases, Palatine Tonsil, Cell Separation, Biology, Monoclonal antibody, Epitope, Pathology and Forensic Medicine, medicine, Animals, PrPC Proteins, Microscopy, Immunoelectron, Follicular dendritic cells, Antibodies, Monoclonal, Germinal center, Cell Biology, Immunogold labelling, Immunohistochemistry, Molecular biology, nervous system diseases, Encephalopathy, Bovine Spongiform, Lymphatic system, biology.protein, Cattle, Lymph Nodes, Lymph, Antibody, Dendritic Cells, Follicular
Abstract

As interaction of cellular prion protein (PrPc) and the infectious agent (PrPres) appears to be a crucial pathogenic step promoted by homology, variation in PrPc isoforms on bovine immune cells may explain the absence of infectivity in most bovine lymph organs. In this study, we examined PrPc expression in bovine lymph organs (tonsils and lymph nodes) and on isolated follicular dendritic cells (FDCs). We used a panel of different monoclonal antibodies (MoAbs) raised against different epitopes of prion protein. Two MoAbs recognise amino acids 79-92 (SAF 34 and SAF 32 Mo-Abs); the 6H4 antibody reacts with a specific peptide comprising the 144-152 amino acids, and the 12F10 MoAb recognises the sequence 142-160. After immunolabelling of frozen sections of lymph organs with 6H4 or 12F10 MoAbs, we detected cellular prion protein in germinal centres. However, using the SAF 34 or SAF 32 antibodies, PrPc was revealed outside the lymphoid tissues. No PrPc was observed in the germinal centres. Therefore, we adapted the method of FDC isolation, making it suitable for the study of PrPc expression on their surface. Using electron microscopy, the presence of PrPc on the surface of FDCs was demonstrated only with 6H4 MoAb. These results suggest that bovine follicular dendritic cells express a particular form of prion protein. Either the N-terminal part of PrPc is cleaved or the accessibility of the specific epitope (79-92) of SAF 34 MoAb is abolished by interaction with other molecules. This particular isoform of PrPc on bovine FDCs might be related to the apparent absence of infectivity in lymph organs in cattle affected by bovine spongiform encephalopathy.

Published
2001
Full Text
View/download PDF

6. Lymphoid cell apoptosis induced by trophoblastic cells: a model of active foeto-placental tolerance

Author

Danièle Zorzi, Olivier Thellin, F. Melot, Georges Hennen, M. Bougoussa, Bernard Coumans, Ahmed Igout, Willy Zorzi, Ernst Heinen, and Laurence Melen

Subjects
Pathology, medicine.medical_specialty, Programmed cell death, Fas Ligand Protein, CD3 Complex, Placenta, Immunology, Cell, Apoptosis, Biology, Jurkat cells, Flow cytometry, Immune tolerance, Jurkat Cells, medicine, Humans, Immunology and Allergy, Lymphocytes, Lymphopoiesis, Cells, Cultured, reproductive and urinary physiology, Membrane Glycoproteins, medicine.diagnostic_test, Molecular biology, Trophoblasts, medicine.anatomical_structure, Cell culture, embryonic structures
Abstract

To test the hypothesis that CD95-L (Fas-L) present on trophoblastic cells plays a part in establishing foeto-placental tolerance by inducing apoptosis of immune defence cells, we cocultured trophoblasts with lymphoid cells and scored the frequency of cell death in these cultures. We prepared human trophoblastic cells from term placentas removed by C-section and placed them in culture for 48 h before introducing the lymphoid cells. We added Jurkat cells, a CD3 + lymphoid cell line, or purified T cells from human blood to the cultured trophoblasts and monitored apoptosis by electron microscopy and flow cytometry after TUNEL or annexin V labelling. The frequency of cell death in the CD3 + cell population was higher when the lymphoid cells were cocultured with trophoblastic cells than when they were cultured alone. This frequency increased with time but was reduced when anti-CD95-L antibodies were added to the culture medium. Cell death was less frequent in the lymphoid cell population when trophoblasts were replaced with human fibroblasts not expressing CD95-L.

Published
1999
Full Text
View/download PDF

7. Demonstration of the expression of CD95 ligand transcript and protein in human placenta

Author

F. Melot, Bernard Coumans, Ahmed Igout, Willy Zorzi, Olivier Thellin, Georges Hennen, Ernst Heinen, and Bernard Lakaye

Subjects
Fas Ligand Protein, Placenta, Uterus, Gene Expression, chemical and pharmacologic phenomena, Biology, Polymerase Chain Reaction, Flow cytometry, Pregnancy, Fetal membrane, hemic and lymphatic diseases, Immune Tolerance, medicine, Humans, Conceptus, RNA, Messenger, fas Receptor, Maternal-Fetal Exchange, DNA Primers, Fetus, Membrane Glycoproteins, Base Sequence, medicine.diagnostic_test, Obstetrics and Gynecology, hemic and immune systems, Flow Cytometry, Fas receptor, Immunohistochemistry, Molecular biology, Trophoblasts, Cell biology, medicine.anatomical_structure, Reproductive Medicine, Apoptosis, embryonic structures, Female, biological phenomena, cell phenomena, and immunity, Developmental Biology
Abstract

Tolerance of the fetal allograft enables the human conceptus to implant itself into the maternal uterus and survive and grow there. This tolerance phenomenon remains largely obscure, notably because it appears to be controlled by multiple mechanisms. CD95 ligand (CD95-L), which can trigger death of CD95-positive cells by apoptosis, may participate in inducing anti-fetus-sensitized CD95-positive T lymphocytes to enter apoptosis. Using immunohistochemistry (first trimester and term placentae), FACS assays (term placenta) and RT-PCR assays (term placenta), the presence of CD95-L protein and mRNA has been shown in crude placental tissue preparations and isolated placental cells. Among the latter, CD95-L expression was detected in trophoblastic cells, fetal blood cells (mRNA only) and also the Hofbauer macrophages. No CD95-L was detected in fibroblasts or fetal endothelial cells. Thus trophoblastic cells, Hofbauer macrophages, and perhaps also fetal blood cells could form a sequential barrier blocking maternal activated defence cells bearing CD95 molecules.

Published
1998
Full Text
View/download PDF

8. Planck 2013 results

Author

T. Poutanen, Olivier Doré, K. Ganga, O. Perdereau, Peter A. R. Ade, Jose M. Diego, Krzysztof M. Gorski, V. Stolyarov, Y. Giraud-Héraud, E. Franceschi, I. Ristorcelli, Martin Kunz, Duncan Hanson, P. R. Christensen, C. Hernández-Monteagudo, P. M. McGehee, Mathieu Remazeilles, Anthony Lasenby, L. Sanselme, Monique Arnaud, Charles R. Lawrence, Jon E. Gudmundsson, L. Pagano, S. Galeotta, F. Piacentini, E. Keihänen, W. Hovest, F. Melot, William T. Reach, Guilaine Lagache, Jean-François Cardoso, Francesca Perrotta, L. Perotto, Allan Hornstrup, George Helou, Etienne Pointecouteau, M. López-Caniego, Alessandro Melchiorri, Kevin M. Huffenberger, Alain Benoit, D. L. Harrison, R. Leonardi, Michele Liguori, Theodore Kisner, Hans Ulrik Nørgaard-Nielsen, C. North, C. Leroy, M. Maris, N. Ponthieu, A. de Rosa, R.-R. Chary, Jo Dunkley, M. Tucci, Stéphane Colombi, J. J. Bock, M. Ashdown, Pavel Naselsky, R. J. Davis, Andrea Zacchei, H. K. Eriksen, Francine R. Marleau, J. W. Bowyer, Fabrizio Villa, M. Bridges, M. Tomasi, F. Cuttaia, W. A. Holmes, B. Racine, A. Chamballu, Torsten A. Enßlin, Locke D. Spencer, Olivier Forni, J. Aumont, S. R. Hildebrandt, A. Benoit-Lévy, Daniel J. Mortlock, M.-A. Miville-Deschênes, M. Giard, E. Pierpaoli, Aurelien A. Fraisse, M. Frailis, Carlo Baccigalupi, E. Hivon, S. Techene, S. Mottet, P. B. Lilje, D. Sutton, W. C. Jones, F. K. Hansen, J. Knoche, Marco Bersanelli, Roberta Paladini, Simon Prunet, Carlo Burigana, Simon D. M. White, P. Bielewicz, B. P. Crill, Lung-Yih Chiang, S. Donzelli, D. Girard, A. Curto, Peter G. Martin, François R. Bouchet, Serge Gratton, A. Sauvé, F.-X. Désert, J. Bobin, G. W. Pratt, D. Herranz, M. Le Jeune, D. Yvon, Michael Rowan-Robinson, Nicola Vittorio, L. P. L. Colombo, F. Matthai, C. Armitage-Caplan, Giorgio Savini, A. Catalano, Gianluca Morgante, T. Riller, Dmitry Novikov, Bruno Maffei, Clive Dickinson, Xin Chen, J.-L. Puget, Pasquale Mazzotta, J.-F. Sygnet, Stéphane Plaszczynski, L. Vibert, X. Dupac, Carol Anne Oxborrow, M. Reinecke, Davide Pietrobon, E. Battaner, L. A. Wade, Daniela Paoletti, F. Pajot, Reijo Keskitalo, M. Bucher, Douglas Scott, Luigi Danese, Dipak Munshi, George Efstathiou, L. Popa, Ben Rusholme, P. Vielva, D. Santos, A. Mennella, Nabila Aghanim, Luca Valenziano, A. Coulais, F. Atrio-Barandela, Calvin B. Netterfield, G. Giardino, T. R. Jaffe, O. Herent, Marcella Massardi, R. Kneissl, Jacques Delabrouille, François Orieux, J.-M. Delouis, M. Migliaccio, N. Mandolesi, J. A. Murphy, A. Moneti, Radek Stompor, Federico Nati, E. P. S. Shellard, Luca Terenzi, C. Combet, Andrew H. Jaffe, G. Umana, G. de Zotti, René J. Laureijs, Mika Juvela, F. Boulanger, Jussi-Pekka Väliviita, G. Patanchon, F. Couchot, I. D. Novikov, Philip Lubin, Fabio Finelli, Peter Meinhold, F. Paci, Sophie Henrot-Versille, Alessandro Gruppuso, Z. Hou, R. D. Davies, F. Noviello, J. González-Nuevo, G. Prézeau, Paolo Natoli, Andrea Zonca, K. Benabed, A. Gregorio, Marian Douspis, H. C. Chiang, J. R. Bond, Michael P. Hobson, Franck Sureau, B. Van Tent, J.-M. Lamarre, L. Mendes, S. Osborne, A. J. Banday, A.-S. Suur-Uski, Sabino Matarrese, H. Dole, Subhabrata Mitra, J. A. Tauber, Hannu Kurki-Suonio, J. Lesgourgues, G. Hurier, C. J. MacTavish, Lloyd Knox, David L. Clements, G. Roudier, P. de Bernardis, C. Rosset, Silvia Masi, Jean-Luc Starck, D. J. Marshall, J. F. Macías-Pérez, Graca Rocha, L. Montier, F. Pasian, J.-P. Bernard, Benjamin D. Wandelt, M. Tristram, Julian Borrill, G. Polenta, M. Linden-Vørnle, Sarah E. Church, E. Martínez-González, M. Piat, D. Tavagnacco, Rafael Rebolo, R. B. Barreiro, R. Sudiwala, S. Ricciardi, Jörg P. Rachen, C. Renault, Tauber, Jan, Aghanim, N., Armitage Caplan, C., Arnaud, M., Ashdown, M., Atrio Barandela, F., Aumont, J., Baccigalupi, C., Banday, A. J., Barreiro, R. B., Battaner, E., Benabed, K., Benoît, A., Benoit Lévy, A., Bernard, J. P., Bersanelli, M., Bielewicz, P., Bobin, J., Bock, J. J., Bonaldi, A., Bonavera, L., Bond, J. R., Borrill, J., Bouchet, F. R., Bridges, M., Bucher, M., Burigana, C., Butler, R. C., Cappellini, B., Cardoso, J. F., Catalano, A., Chamballu, A., Chen, X., Chiang, L. Y., Christensen, P. R., Church, S., Colombi, S., Colombo, L. P. L., Crill, B. P., Cruz, M., Curto, A., Cuttaia, F., Danese, L., Davies, R. D., Davis, R. J., De Bernardis, P., De Rosa, A., De Zotti, G., Delabrouille, J., Dickinson, C., Diego, J. M., Dole, H., Donzelli, S., Doré, O., Douspis, M., Dupac, X., Efstathiou, G., Enßlin, T. A., Eriksen, H. K., Falvella, M. C., Finelli, F., Forni, O., Frailis, M., Franceschi, E., Gaier, T. C., Galeotta, S., Ganga, K., Giard, M., Giardino, G., Giraud Héraud, Y., Gjerløw, E., González Nuevo, J., Górski, K. M., Gratton, S., Gregorio, Anna, Gruppuso, A., Hansen, F. K., Hanson, D., Harrison, D., Henrot Versillé, S., Hernández Monteagudo, C., Herranz, D., Hildebrandt, S. R., Hivon, E., Hobson, M., Holmes, W. A., Hornstrup, A., Hovest, W., Huffenberger, K. M., Jaffe, A. H., Jaffe, T. R., Jewell, J., Jones, W. C., Juvela, M., Kangaslahti, P., Keihänen, E., Keskitalo, R., Kiiveri, K., Kisner, T. S., Knoche, J., Knox, L., Kunz, M., Kurki Suonio, H., Lagache, G., Lähteenmäki, A., Lamarre, J. M., Lasenby, A., Lattanzi, M., Laureijs, R. J., Lawrence, C. R., Leach, S., Leahy, J. P., Leonardi, R., Lesgourgues, J., Liguori, M., Lilje, P. B., Linden Vørnle, M., Lindholm, V., López Caniego, M., Lubin, P. M., MacIás Pérez, J. F., Maggio, G., Maino, D., Mandolesi, N., Maris, M., Marshall, D. J., Martin, P. G., Martínez González, E., Masi, S., Massardi, M., Matarrese, S., Matthai, F., Mazzotta, P., Meinhold, P. R., Melchiorri, A., Mendes, L., Mennella, A., Migliaccio, M., Mitra, S., Moneti, A., Montier, L., Morgante, G., Morisset, N., Mortlock, D., Moss, A., Munshi, D., Naselsky, P., Natoli, P., Netterfield, C. B., Nørgaard Nielsen, H. U., Novikov, D., Novikov, I., O'Dwyer, I. J., Osborne, S., Paci, F., Pagano, L., Paladini, R., Paoletti, D., Partridge, B., Pasian, F., Patanchon, G., Peel, M., Perdereau, O., Perotto, L., Perrotta, F., Pierpaoli, E., Pietrobon, D., Plaszczynski, S., Platania, P., Pointecouteau, E., Polenta, G., Ponthieu, N., Popa, L., Poutanen, T., Pratt, G. W., Prézeau, G., Prunet, S., Puget, J. L., Rachen, J. P., Reach, W. T., Rebolo, R., Reinecke, M., Remazeilles, M., Ricciardi, S., Riller, T., Robbers, G., Rocha, G., Rosset, C., Rossetti, M., Roudier, G., Rubinõ Martín, J. A., Rusholme, B., Salerno, E., Sandri, M., Santos, D., Scott, D., Seiffert, M. D., Shellard, E. P. S., Spencer, L. D., Starck, J. L., Stolyarov, V., Stompor, R., Sureau, F., Sutton, D., Suur Uski, A. S., Sygnet, J. F., Tauber, J. A., Tavagnacco, Daniele, Terenzi, L., Toffolatti, L., Tomasi, M., Tristram, M., Tucci, M., Tuovinen, J., Türler, M., Umana, G., Valenziano, L., Valiviita, J., Van Tent, B., Varis, J., Vielva, P., Villa, F., Vittorio, N., Wade, L. A., Wandelt, B. D., Watson, R., Wehus, I. K., White, S. D. M., Wilkinson, A., Yvon, D., Zacchei, A., Zonca, A., Hélium : du fondamental aux applications (HELFA), Institut Néel (NEEL), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS), APC - Cosmologie, AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Etude du Rayonnement et de la Matière en Astrophysique (LERMA), École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Centre National de la Recherche Scientifique (CNRS), APC - Gravitation (APC-Gravitation), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Max-Planck-Institut für Gravitationsphysik ( Albert-Einstein-Institut ) (AEI), Max-Planck-Gesellschaft-Max-Planck-Gesellschaft, Laboratoire de l'Accélérateur Linéaire (LAL), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), PLANCK, Universidad de Cantabria, Hélium : du fondamental aux applications (NEEL - HELFA), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Max-Planck-Institut für Gravitationsphysik ( Albert-Einstein-Institut ) (AEI), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Anne Lähteenmäki Group, Department of Electronics and Nanoengineering, Aalto-yliopisto, Aalto University, HELFA - Hélium : du fondamental aux applications, Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Physique Corpusculaire et Cosmologie - Collège de France (PCC), Collège de France (CdF)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Collège de France (CdF)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-AstroParticule et Cosmologie (APC (UMR_7164)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Max-Planck-Institut für Gravitationsphysik ( Albert-Einstein-Institut ) (AEI), Department of Physics, and Helsinki Institute of Physics

Subjects
Astronomy, Cosmic microwave background, data analysis, Astrophysics, cosmic background radiation, Surveys, Cosmic background radiation, NOISE, RADIOMETERS, data analysis [Methods], observations [Cosmology], Survey, cosmology: observations, surveys [cosmic background radiation, methods], Physics, Detector, Astrophysics::Instrumentation and Methods for Astrophysics, Computer Science::Computers and Society, DATA SETS, Physics::Space Physics, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, Astrophysics - Instrumentation and Methods for Astrophysics, Noise (radio), Astrophysics and Astronomy, [PHYS.ASTR.IM]Physics [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM], education, FOS: Physical sciences, observation [Cosmology], Computer Science::Digital Libraries, NO, Settore FIS/05 - Astronomia e Astrofisica, surveys, Calibration, PRE-LAUNCH STATUS, Angular resolution, Instrumentation and Methods for Astrophysics (astro-ph.IM), methods: data analysis, Radiometer, MAP-MAKING ALGORITHM, Instrument Data, Spectral density, Astronomy and Astrophysics, Astronomy and Astrophysic, 115 Astronomy, Space science, Cosmology: observations, Methods: data analysis, Space and Planetary Science, [SDU.ASTR.IM]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Instrumentation and Methods for Astrophysic [astro-ph.IM], data analysi [Methods], cosmology
Abstract

We describe the data processing pipeline of the Planck Low Frequency Instrument (LFI) data processing centre (DPC) to create and characterize full-sky maps based on the first 15.5 months of operations at 30, 44, and 70 GHz. In particular, we discuss the various steps involved in reducing the data, from telemetry packets through to the production of cleaned, calibrated timelines and calibrated frequency maps. Data are continuously calibrated using the modulation induced on the mean temperature of the cosmic microwave background radiation by the proper motion of the spacecraft. Sky signals other than the dipole are removed by an iterative procedure based on simultaneous fitting of calibration parameters and sky maps. Noise properties are estimated from time-ordered data after the sky signal has been removed, using a generalized least squares map-making algorithm. A destriping code (Madam) is employed to combine radiometric data and pointing information into sky maps, minimizing the variance of correlated noise. Noise covariance matrices, required to compute statistical uncertainties on LFI and Planck products, are also produced. Main beams are estimated down to the ≈−20 dB level using Jupiter transits, which are also used for the geometrical calibration of the focal plane., This work was supported by the Academy of Finland grants 253204, 256265, and 257989. We acknowledge financial support provided by the Spanish Ministerio de Ciencia e Innovaciõn through the Plan Nacional del Espacio y Plan Nacional de Astronomia y Astrofisica. The development of Planck has been supported by: ESA; CNES and CNRS/INSU-IN2P3-INP (France); ASI, CNR, and INAF (Italy); NASA and DoE (USA); STFC and UKSA (UK); CSIC, MICINN and JA (Spain); Tekes, AoF and CSC (Finland); DLR and MPG (Germany); CSA (Canada); DTU Space (Denmark); SER/SSO (Switzerland); RCN (Norway); SFI (Ireland); FCT/MCTES (Portugal); and PRACE (EU).

Published
2014
Full Text
View/download PDF

9. GATE: a simulation toolkit for PET and SPECT

Author

David Guez, J. Perez, S. Kerhoas-Cavata, Yong Choi, M. Krieguer, Dimitris Visvikis, P. Bruyndonckx, J. M. Vieira, E. Pennacchio, Dennis R. Schaart, V. Kohli, Ludovic Ferrer, G. Largeron, Vincent Breton, Tae Yong Song, Arion F. Chatziioannou, P. F. Honore, M. Rey, Giovanni Santin, Sébastien Jan, E. Wieers, Christian Morel, Charles Schmidtlein, Claude Comtat, Michel Koole, Stephen J. Glick, F. Mayet, Assen S. Kirov, C. J. Groiselle, Lydia Maigne, D. Strul, F. Lamare, F. R. Rannou, F. Melot, Karine Assié, Remi Barbier, D. Lazaro, Y. H. Chung, D. Donnarieix, Peter M. Bloomfield, Steven Staelens, David Brasse, Luc Simon, D.J. van der Laan, D. Autret, Manuel Bardiès, C. Merheb, R. T. Van de Walle, Stéphane Avner, Uwe Pietrzyk, Marnix C. Maas, Irène Buvat, Carole Lartizien, Institut de Recherches Subatomiques (IReS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Cancéropôle du Grand Est-Université Louis Pasteur - Strasbourg I-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Corpusculaire - Clermont-Ferrand (LPC), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de Physique Nucléaire de Lyon (IPNL), Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches Subatomiques ( IReS ), Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Cancéropôle du Grand Est-Université Louis Pasteur - Strasbourg I-Centre National de la Recherche Scientifique ( CNRS ), Laboratoire de Physique Corpusculaire - Clermont-Ferrand ( LPC ), Université Blaise Pascal - Clermont-Ferrand 2 ( UBP ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Centre National de la Recherche Scientifique ( CNRS ), Institut de Physique Nucléaire de Lyon ( IPNL ), Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Centre National de la Recherche Scientifique ( CNRS ), Laboratoire de Physique Subatomique et de Cosmologie ( LPSC ), and Université Joseph Fourier - Grenoble 1 ( UJF ) -Institut polytechnique de Grenoble - Grenoble Institute of Technology ( Grenoble INP ) -Institut National de Physique Nucléaire et de Physique des Particules du CNRS ( IN2P3 ) -Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique ( CNRS ) -Université Grenoble Alpes ( UGA )

Subjects
Computer science, monte-carlo simulations, [PHYS.PHYS.PHYS-BIO-PH]Physics [physics]/Physics [physics]/Biological Physics [physics.bio-ph], Monte Carlo method, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, FOS: Physical sciences, Field (computer science), Article, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, platform, 0302 clinical medicine, Image reconstruction algorithm, [ PHYS.PHYS.PHYS-BIO-PH ] Physics [physics]/Physics [physics]/Biological Physics [physics.bio-ph], ddc:570, Medical imaging, Radiology, Nuclear Medicine and imaging, Computer Simulation, Physics - Biological Physics, validation, Tomography, Emission-Computed, Single-Photon, detector, Radiological and Ultrasound Technology, business.industry, Detector, Reproducibility of Results, Modular design, Physics - Medical Physics, 3. Good health, Biological Physics (physics.bio-ph), Feature (computer vision), 030220 oncology & carcinogenesis, beam, Thermodynamics, Medical Physics (physics.med-ph), Tomography, business, Monte Carlo Method, Computer hardware, Software
Abstract

Monte Carlo simulation is an essential tool in emission tomography that can assist in the design of new medical imaging devices, the optimization of acquisition protocols and the development or assessment of image reconstruction algorithms and correction techniques. GATE, the Geant4 Application for Tomographic Emission, encapsulates the Geant4 libraries to achieve a modular, versatile, scripted simulation toolkit adapted to the field of nuclear medicine. In particular, GATE allows the description of time-dependent phenomena such as source or detector movement, and source decay kinetics. This feature makes it possible to simulate time curves under realistic acquisition conditions and to test dynamic reconstruction algorithms. This paper gives a detailed description of the design and development of GATE by the OpenGATE collaboration, whose continuing objective is to improve, document and validate GATE by simulating commercially available imaging systems for PET and SPECT. Large effort is also invested in the ability and the flexibility to model novel detection systems or systems still under design. A public release of GATE licensed under the GNU Lesser General Public License can be downloaded at http:/www-lphe.epfl.ch/GATE/. Two benchmarks developed for PET and SPECT to test the installation of GATE and to serve as a tutorial for the users are presented. Extensive validation of the GATE simulation platform has been started, comparing simulations and measurements on commercially available acquisition systems. References to those results are listed. The future prospects towards the gridification of GATE and its extension to other domains such as dosimetry are also discussed. ispartof: Physics in medicine and biology vol:49 issue:19 pages:4543-4561 ispartof: location:England status: published

Published
2004
Full Text
View/download PDF

10. FDC-B1: a new monoclonal antibody directed against bovine follicular dendritic cells

Author

B Robert, Olivier Jolois, F. Melot, Ernst Heinen, Nadine Antoine, A Collard, and Valérie Defaweux

Subjects
medicine.drug_class, Lymphoid Tissue, Swine, Immunology, Population, Fluorescent Antibody Technique, Biology, Monoclonal antibody, Mice, Immune system, Mouse monoclonal antibody, Antigen, medicine, Animals, Humans, education, education.field_of_study, Mice, Inbred BALB C, Sheep, General Veterinary, Follicular dendritic cells, Goats, Germinal center, Antibodies, Monoclonal, Germinal Center, Molecular biology, Immunohistochemistry, Mice, Inbred C57BL, Microscopy, Electron, Lymphatic system, Cattle, Female, Dendritic Cells, Follicular
Abstract

Follicular dendritic cells (FDCs) are a unique population of accessory cells located in the light zone of the germinal centres of lymphoid follicles. Their involvement in the generation of humoral immune responses implies a potential role for these cells in many disorders. Indeed, in prion diseases, FDCs seem to be the major sites of extraneuronal cellular prion protein expression and the principal sites of the infectious agent accumulation in lymphoid organs. The identification of FDC is useful for the analysis of their distribution in reactive lymphoid tissue as well as in pathological conditions. The production and characterisation of a new mouse monoclonal antibody directed against bovine follicular dendritic cells (FDC-B1) is reported. The antigen detected by FDC-B1 is expressed exclusively on the surface of FDCs in ruminant lymphoid organs. The antigen has an approximate molecular weight of 28 kDa.

Published
2004

11. In-flight calibration and verification of the Planck-LFI instrument

Author

M. Frailis, R. C. Butler, P. Battaglia, Michele Maris, Christopher J. Watson, Luis Mendes, P. Wilson, Rodrigo Leonardi, M. Tomasi, Mike Krassenburg, Marco Bersanelli, Gianluca Morgante, Steve Foley, Frederick Melot, Anna Gregorio, J. A. Tauber, A. Mennella, Andrea Zonca, Daniele Tavagnacco, Althea Wilkinson, Andrea Zacchei, Dave Pearson, Damien Texier, Leticia Perez Cuevas, Maryse Charra, Thierry Maciaszek, Peter Meinhold, Richard J. Davis, Mauro Casale, Luca Terenzi, E. Franceschi, Michelle Baker, Steve Lowe, René J. Laureijs, Patrick Rihet, S. Galeotta, Luca Stringhetti, Fabrizio Villa, Patrick Stassi, Cristian Franceschet, F. Cuttaia, M. Sandri, Nazzareno Mandolesi, Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Institut d'astrophysique spatiale (IAS), Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Centre National d'Études Spatiales [Toulouse] (CNES), PLANCK, Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Sud - Paris 11 (UP11), Gregorio, Anna, F., Cuttaia, A., Mennella, M., Bersanelli, M., Mari, P., Meinhold, M., Sandri, L., Terenzi, M., Tomasi, F., Villa, M., Fraili, G., Morgante, D., Pearson, A., Zacchei, P., Battaglia, R. C., Butler, R., Davi, C., Franceschet, E., Franceschi, S., Galeotta, R., Leonardi, S., Lowe, N., Mandolesi, F., Melot, L., Mende, P., Stassi, L., Stringhetti, Tavagnacco, Daniele, A., Zonca, A., Wilkinson, P., Wilson, M., Charra, T., Maciaszek, S., Foley, C. J., Watson, M., Casale, R., Laureij, J., Tauber, D., Texier, M., Baker, L., Perez Cueva, M., Krassenburg, and P., Rihet

Subjects
B.4.4, B.8.0, Microwave radiometers, Instruments for CMB observations, Instrument optimisation, Space instrumentation, J.2, Computer science, Calibration (statistics), [SDU.ASTR.CO]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO], FOS: Physical sciences, 01 natural sciences, 7. Clean energy, [PHYS.ASTR.CO]Physics [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO], symbols.namesake, Instruments for CMB observation, 85-05 (primary), 0103 physical sciences, Calibration, Electronics, Planck, 010303 astronomy & astrophysics, Instrumentation, Instrumentation and Methods for Astrophysics (astro-ph.IM), Mathematical Physics, Simulation, 010308 nuclear & particles physics, Astrophysics::Instrumentation and Methods for Astrophysics, Microwave radiometer, Noise, symbols, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

In this paper we discuss the Planck-LFI in-flight calibration campaign. After a brief overview of the ground test campaigns, we describe in detail the calibration and performance verification (CPV) phase, carried out in space during and just after the cool-down of LFI. We discuss in detail the functionality verification, the tuning of the front-end and warm electronics, the preliminary performance assessment and the thermal susceptibility tests. The logic, sequence, goals and results of the in-flight tests are discussed. All the calibration activities were successfully carried out and the instrument response was comparable to the one observed on ground. For some channels the in-flight tuning activity allowed us to improve significantly the noise performance., Comment: Long technical paper on Planck LFI in flight calibration campaign: 109 pages in this (not final) version, 100 page in the final JINST version

Published
2013
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results