425 results on '"F. Yamazaki"'
Search Results
2. Review article: Detection of inundation areas due to the 2015 Kanto and Tohoku torrential rain in Japan based on multi-temporal ALOS-2 imagery
- Author
-
W. Liu and F. Yamazaki
- Subjects
Environmental technology. Sanitary engineering ,TD1-1066 ,Geography. Anthropology. Recreation ,Environmental sciences ,GE1-350 ,Geology ,QE1-996.5 - Abstract
Torrential rain triggered by two typhoons hit the Kanto and Tohoku regions of Japan from 9 to 11 September 2015. Due to the record-breaking amount of rainfall, several riverbanks were overflowed and destroyed, causing floods over wide areas. The PALSAR-2 sensor on board the ALOS-2 satellite engaged in emergency observations of the affected areas during and after the heavy rain. Two pre-event and three co-event PALSAR-2 images were employed in this study to extract flooded areas in the city of Joso, Ibaraki Prefecture. The backscattering coefficient of the river water was investigated first using the PALSAR-2 intensity images and a land-cover map with a 10 m resolution. The inundation areas were then extracted by setting threshold values for backscattering from water surfaces in the three temporal synthetic aperture radar (SAR) images. The extracted results were modified by considering the land cover and a digital elevation model (DEM). Next, the inundated built-up urban areas were extracted from the changes in SAR backscattering. The results were finally compared with those from visual inspections of airborne imagery by the Geospatial Information Authority of Japan (GSI), and more than 85 % of the maximum inundation areas were extracted successfully.
- Published
- 2018
- Full Text
- View/download PDF
3. Detection of collapsed buildings from lidar data due to the 2016 Kumamoto earthquake in Japan
- Author
-
L. Moya, F. Yamazaki, W. Liu, and M. Yamada
- Subjects
Environmental technology. Sanitary engineering ,TD1-1066 ,Geography. Anthropology. Recreation ,Environmental sciences ,GE1-350 ,Geology ,QE1-996.5 - Abstract
The 2016 Kumamoto earthquake sequence was triggered by an Mw 6.2 event at 21:26 on 14 April. Approximately 28 h later, at 01:25 on 16 April, an Mw 7.0 event (the mainshock) followed. The epicenters of both events were located near the residential area of Mashiki and affected the region nearby. Due to very strong seismic ground motion, the earthquake produced extensive damage to buildings and infrastructure. In this paper, collapsed buildings were detected using a pair of digital surface models (DSMs), taken before and after the 16 April mainshock by airborne light detection and ranging (lidar) flights. Different methods were evaluated to identify collapsed buildings from the DSMs. The change in average elevation within a building footprint was found to be the most important factor. Finally, the distribution of collapsed buildings in the study area was presented, and the result was consistent with that of a building damage survey performed after the earthquake.
- Published
- 2018
- Full Text
- View/download PDF
4. Calculation of coseismic displacement from lidar data in the 2016 Kumamoto, Japan, earthquake
- Author
-
L. Moya, F. Yamazaki, W. Liu, and T. Chiba
- Subjects
Environmental technology. Sanitary engineering ,TD1-1066 ,Geography. Anthropology. Recreation ,Environmental sciences ,GE1-350 ,Geology ,QE1-996.5 - Abstract
The spatial distribution of the coseismic displacements that occurred along the Futagawa fault during the 2016 Kumamoto earthquake of Mw 7.0 was estimated using airborne light detection and ranging (lidar) data. In this study, a pair of digital surface models (DSMs) obtained from the high-density lidar data before and after the mainshock on 16 April 2016 were used. A window matching search approach based on the correlation coefficient between the two DSMs was used to estimate the geodetic displacement in the near-field region. The results showed good agreements with the geodetic displacements calculated from strong-motion acceleration records and coincided with the fault line surveyed by the Geological Survey of Japan.
- Published
- 2017
- Full Text
- View/download PDF
5. EXTRACTION OF FLOODED AREAS DUE THE 2015 KANTO-TOHOKU HEAVY RAINFALL IN JAPAN USING PALSAR-2 IMAGES
- Author
-
F. Yamazaki and W. Liu
- Subjects
Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Applied optics. Photonics ,TA1501-1820 - Abstract
Triggered by two typhoons, heavy rainfall hit Kanto and Tohoku regions of Japan from September 9 to 11, 2015. Increased river water by the continuous rainfall overflowed and destroyed several river banks and caused damaging floods in wide areas. PALSAR-2 onboard ALOS-2 satellite carried out emergency observation for the impacted areas during and after the heavy rainfall. In this study, two pre-event and four co- and post-event PALSAR-2 images were used to extract the inundation area in Joso city, Ibaraki prefecture. First, using the pre-event SAR intensity image and a detailed topographic map, the backscattering coefficient of river water was investigated. Then the flooded areas were extracted by a common threshold value of backscatter for water bodies in the six temporal images. The colour composite of the sigma naught values was also made to visualize pixels that had been converted from ground to water. Finally, the extracted results were compared with those from the visual interpretation of aerial photographs and field survey reports. This comparison revealed that the accuracy of the flood extraction was fairly good for agricultural lands and non-urban land uses. But for built-up urban areas, it was not easy to extract water body since radar illumination did to reach the ground (water) surface.
- Published
- 2016
- Full Text
- View/download PDF
6. Estimation of three-dimensional crustal movements in the 2011 Tohoku-Oki, Japan, earthquake from TerraSAR-X intensity images
- Author
-
W. Liu, F. Yamazaki, M. Matsuoka, T. Nonaka, and T. Sasagawa
- Subjects
Environmental technology. Sanitary engineering ,TD1-1066 ,Geography. Anthropology. Recreation ,Environmental sciences ,GE1-350 ,Geology ,QE1-996.5 - Abstract
The Tohoku-Oki earthquake on 11 March 2011 caused significant widespread crustal movements. In a previous study, we proposed a method for capturing two-dimensional (2-D) surface displacements from a pair of pre- and post-event TerraSAR-X (TSX) intensity images. However, it is impossible to detect three-dimensional (3-D) displacements from one pair of TSX images. In this study, three pairs of pre- and post-event TSX images taken on different paths were used to estimate 3-D crustal movements. The relationship between the actual 3-D displacements and the converted 2-D movements in the synthetic-aperture radar (SAR) images was derived based on the observation model of a SAR sensor. The 3-D movements were then calculated from three sets of detected 2-D movements that occurred within a short time period. Compared with GPS observations, the proposed method was found to be capable of detecting the 3-D crustal movements with sub-pixel accuracy.
- Published
- 2015
- Full Text
- View/download PDF
7. Developing Tsunami fragility curves using remote sensing and survey data of the 2010 Chilean Tsunami in Dichato
- Author
-
E. Mas, S. Koshimura, A. Suppasri, M. Matsuoka, M. Matsuyama, T. Yoshii, C. Jimenez, F. Yamazaki, and F. Imamura
- Subjects
Environmental technology. Sanitary engineering ,TD1-1066 ,Geography. Anthropology. Recreation ,Environmental sciences ,GE1-350 ,Geology ,QE1-996.5 - Abstract
On 27 February 2010, a megathrust earthquake of Mw = 8.8 generated a destructive tsunami in Chile. It struck not only Chilean coast but propagated all the way to Japan. After the event occurred, the post-tsunami survey team was assembled, funded by the Japan Science and Technology Agency (JST), to survey the area severely affected by the tsunami. The tsunami damaged and destroyed numerous houses, especially in the town of Dichato. In order to estimate the structural fragility against tsunami hazard in this area, tsunami fragility curves were developed. Surveyed data of inundation depth and visual inspection of satellite images of Dichato were used to classify the damage to housing. A practical method suitable when there are limitations on available data for numerical simulation or damage evaluation from surveys is presented here. This study is the first application of tsunami fragility curves on the South American Pacific coast and it might be of practical use for communities with similar characteristics along the west Pacific coast. The proposed curve suggests that structures in Dichato will be severely damaged – with a 68% probability – already at 2 m tsunami inundation depth.
- Published
- 2012
- Full Text
- View/download PDF
8. 546 The correlation between the vascular calcification score of the coronary artery and the abdominal aorta in patients with psoriasis
- Author
-
T.N. Huynh, F. Yamazaki, I. Kishimoto, A. Tanaka, Y. Son, Y. Ozaki, K. Takehana, and H. Tanizaki
- Subjects
Cell Biology ,Dermatology ,Molecular Biology ,Biochemistry - Published
- 2023
9. Palisaded neutrophilic and granulomatous dermatitis associated with systemic lupus erythematosus: possible involvement of CD163
- Author
-
S, Terai, I, Ueda-Hayakawa, C T H, Nguyen, N T M, Ly, F, Yamazaki, N, Kambe, Y, Son, and H, Okamoto
- Subjects
Adult ,Granuloma ,Sex Factors ,Antigens, CD ,Neutrophils ,Macrophages ,Antigens, Differentiation, Myelomonocytic ,Humans ,Lupus Erythematosus, Systemic ,Dermatitis ,Female ,Receptors, Cell Surface ,Skin - Abstract
Palisaded neutrophilic and granulomatous dermatitis (PNGD) is a commonly occurring condition related to systemic autoimmune disease. It is characterized histopathologically by a distinct pattern of granulomatous inflammation in the presence or absence of leukocytoclastic vasculitis. The properties of granulomatous cells in PNGD are still uncertain.We sought further investigation on the phenotype of the infiltrated cells in PNGD from two patients with systemic lupus erythematosus (SLE) and reviewed the previous published reports in order to provide a comprehensive summary on the clinical features of PNGD in SLE.The immunohistochemical features of granulomatous cells in PNGD associated with SLE were analyzed. Immunohistochemical studies were performed on sections from our two cases using antibodies against CD68, CD163, CD15, Factor XIIIa, myeloperoxidase and neutrophil elastase. The clinical characteristics of the SLE patients who developed PNGD were also evaluated. We included all cases retrieved through a PubMed search with the key words PNGD and SLE.Cutaneous lesions consisted of erythematous plaques distributed on the face and upper limbs in both cases. The infiltrated cells were mainly positive for CD68 and CD163, a phenotype suggestive of M2 macrophages. Some mature neutrophils and lymphocytes were also present. A review of the literature of PNGD associated with SLE revealed a predominance in females, high prevalence of lupus nephritis and a good response to systemic steroids, with frequent skin lesions relapses during tapering of the treatment.This study examined only two cases; the pathogenesis of the disease remains to be clarified.PNGD lesions were abundantly infiltrated by M2 macrophages, suggesting that they may have a role in this condition. SLE accompanied by PNGD might be associated with lupus nephritis and frequent relapses of skin lesions.
- Published
- 2018
10. PCN35 SURVEILLANCE FOR PATIENTS WITH LI-FRAUMENI SYNDROME
- Author
-
C. Hamashima, T. Katayama, F. Yamazaki, and T. Terasaw
- Subjects
Oncology ,medicine.medical_specialty ,business.industry ,Li–Fraumeni syndrome ,Health Policy ,Internal medicine ,Public Health, Environmental and Occupational Health ,medicine ,business ,medicine.disease - Published
- 2019
11. MEDULLOBLASTOMA
- Author
-
G. Vaidyanathan, S. Gururangan, D. Bigner, M. Zalutsky, M. Morfouace, A. Shelat, J. Megan, B. B. Freeman, S. Robinson, S. Throm, J. M. Olson, X.-N. Li, K. R. Guy, G. Robinson, C. Stewart, A. Gajjar, M. Roussel, N. Sirachainan, S. Pakakasama, U. Anurathapan, A. Hansasuta, M. Dhanachai, C. Khongkhatithum, S. Hongeng, A. Feroze, K.-S. Lee, S. Gholamin, Z. Wu, B. Lu, S. Mitra, S. Cheshier, P. Northcott, C. Lee, T. Zichner, P. Lichter, J. Korbel, R. Wechsler-Reya, S. Pfister, I. P. T. Project, K. K.-W. Li, T. Xia, F. M. T. Ma, R. Zhang, L. Zhou, K.-M. Lau, H.-K. Ng, L. Lafay-Cousin, S. Chi, J. Madden, A. Smith, E. Wells, E. Owens, D. Strother, N. Foreman, R. Packer, E. Bouffet, T. Wataya, J. Peacock, M. D. Taylor, D. Ivanov, M. Garnett, T. Parker, C. Alexander, L. Meijer, R. Grundy, P. Gellert, M. Ashford, D. Walker, J. Brent, F. Z. Cader, D. Ford, A. Kay, R. Walsh, G. Solanki, A. Peet, M. English, T. Shalaby, G. Fiaschetti, S. Baulande, N. Gerber, M. Baumgartner, M. Grotzer, T. Hayase, Y. Kawahara, M. Yagi, T. Minami, N. Kanai, T. Yamaguchi, A. Gomi, A. Morimoto, R. Hill, S. Kuijper, J. Lindsey, E. Schwalbe, K. Barker, J. Boult, D. Williamson, Z. Ahmad, A. Hallsworth, S. Ryan, E. Poon, R. Ruddle, F. Raynaud, L. Howell, C. Kwok, A. Joshi, S. L. Nicholson, S. Crosier, S. Wharton, K. Robson, A. Michalski, D. Hargrave, T. Jacques, B. Pizer, S. Bailey, F. Swartling, K. Petrie, W. Weiss, L. Chesler, S. Clifford, L. Kitanovski, T. Prelog, B. F. Kotnik, M. Debeljak, M. A. Grotzer, A. Gevorgian, E. Morozova, I. Kazantsev, T. Iukhta, S. Safonova, E. Kumirova, Y. Punanov, B. Afanasyev, O. Zheludkova, W. Grajkowska, M. Pronicki, B. Cukrowska, B. Dembowska-Baginska, M. Lastowska, A. Murase, S. Nobusawa, Y. Gemma, F. Yamazaki, A. Masuzawa, T. Uno, T. Osumi, Y. Shioda, C. Kiyotani, T. Mori, K. Matsumoto, H. Ogiwara, N. Morota, J. Hirato, A. Nakazawa, K. Terashima, T. Fay-McClymont, K. Walsh, D. Mabbott, D. Sturm, P. A. Northcott, D. T. W. Jones, A. Korshunov, S. M. Pfister, M. Kool, C. Hooper, S. Hawes, U. Kees, N. Gottardo, P. Dallas, A. Siegfried, A. I. Bertozzi, A. Sevely, N. Loukh, C. Munzer, C. Miquel, F. Bourdeaut, T. Pietsch, C. Dufour, M. B. Delisle, D. Kawauchi, J. Rehg, D. Finkelstein, F. Zindy, T. Phoenix, R. Gilbertson, J. Trubicka, M. Borucka-Mankiewicz, E. Ciara, K. Chrzanowska, M. Perek-Polnik, D. Abramczuk-Piekutowska, D. Jurkiewicz, S. Luczak, P. Kowalski, M. Krajewska-Walasek, C. Sheila, S. Lee, C. Foster, B. Manoranjan, M. Pambit, R. Berns, A. Fotovati, C. Venugopal, K. O'Halloran, A. Narendran, C. Hawkins, V. Ramaswamy, M. Taylor, A. Singhal, J. Hukin, R. Rassekh, S. Yip, S. Singh, C. Duhman, S. Dunn, T. Chen, S. Rush, H. Fuji, Y. Ishida, T. Onoe, T. Kanda, Y. Kase, H. Yamashita, S. Murayama, Y. Nakasu, T. Kurimoto, A. Kondo, S. Sakaguchi, J. Fujimura, M. Saito, T. Arakawa, H. Arai, T. Shimizu, E. Jurkiewicz, P. Daszkiewicz, M. Drogosiewicz, V. Hovestadt, I. Buchhalter, N. N. Jager, A. Stuetz, P. Johann, C. Schmidt, M. Ryzhova, P. Landgraf, M. Hasselblatt, U. Schuller, M.-L. Yaspo, A. von Deimling, R. Eils, A. Modi, M. Patel, M. Berk, L.-x. Wang, G. Plautz, H. Camara-Costa, A. Resch, C. Lalande, V. Kieffer, G. Poggi, C. Kennedy, K. Bull, G. Calaminus, J. Grill, F. Doz, S. Rutkowski, M. Massimino, R.-D. Kortmann, B. Lannering, G. Dellatolas, M. Chevignard, D. Solecki, P. McKinnon, J. Olson, J. Hayden, D. Ellison, M. Buss, M. Remke, J. Lee, T. Caspary, R. Castellino, M. Sabel, G. Gustafsson, G. Fleischhack, M. Benesch, A. Navajas, R. Reddingius, M.-B. Delisle, D. Lafon, N. Sevenet, G. Pierron, O. Delattre, J. Ecker, I. Oehme, R. Mazitschek, M. Lodrini, H. E. Deubzer, A. E. Kulozik, O. Witt, T. Milde, D. Patmore, N. Boulos, K. Wright, S. Boop, T. Janicki, S. Burzynski, G. Burzynski, A. Marszalek, J. Triscott, M. Green, S. R. Rassekh, B. Toyota, C. Dunham, S. E. Dunn, K.-W. Liu, Y. Pei, L. Genovesi, P. Ji, M. Davis, C. G. Ng, Y.-J. Cho, N. Jenkins, N. Copeland, B. Wainwright, Y. Tang, S. Schubert, B. Nguyen, S. Masoud, A. Lee, M. Willardson, P. Bandopadhayay, G. Bergthold, S. Atwood, R. Whitson, J. Qi, R. Beroukhim, J. Tang, A. Oro, B. Link, J. Bradner, S. G. Vallero, D. Bertin, M. E. Basso, C. Milanaccio, P. Peretta, A. Cama, A. Mussano, S. Barra, G. Morana, I. Morra, P. Nozza, F. Fagioli, M. L. Garre, A. Darabi, E. Sanden, E. Visse, N. Stahl, P. Siesjo, D. Vaka, F. Vasquez, B. Weir, G. Cowley, C. Keller, W. Hahn, I. C. Gibbs, S. Partap, K. Yeom, M. Martinez, H. Vogel, S. S. Donaldson, P. Fisher, S. Perreault, L. Guerrini-Rousseau, S. Pujet, V. Kieffer-Renaux, M. A. Raquin, P. Varlet, A. Longaud, C. Sainte-Rose, D. Valteau-Couanet, J. Staal, L. S. Lau, H. Zhang, W. J. Ingram, Y. J. Cho, Y. Hathout, K. Brown, B. R. Rood, M. Handler, T. Hankinson, B. K. Kleinschmidt-Demasters, S. Hutter, D. T. Jones, N. Kagawa, R. Hirayama, N. Kijima, Y. Chiba, M. Kinoshita, K. Takano, D. Eino, S. Fukuya, F. Yamamoto, K. Nakanishi, N. Hashimoto, Y. Hashii, J. Hara, T. Yoshimine, J. Wang, C. Guo, Q. Yang, Z. Chen, I. Filipek, E. Swieszkowska, M. Tarasinska, D. Perek, R. Kebudi, B. Koc, O. Gorgun, F. Y. Agaoglu, J. Wolff, E. Darendeliler, K. Kerl, J. Gronych, J. McGlade, R. Endersby, H. Hii, T. Johns, J. Sastry, D. Murphy, M. Ronghe, C. Cunningham, F. Cowie, R. Jones, A. Calisto, M. Sangra, C. Mathieson, J. Brown, K. Phuakpet, V. Larouche, U. Bartels, T. Ishida, D. Hasegawa, K. Miyata, S. Ochi, A. Saito, A. Kozaki, T. Yanai, K. Kawasaki, K. Yamamoto, A. Kawamura, T. Nagashima, Y. Akasaka, T. Soejima, M. Yoshida, Y. Kosaka, A. von Bueren, T. Goschzik, R. Kortmann, K. von Hoff, C. Friedrich, A. z. Muehlen, M. Warmuth-Metz, N. Soerensen, F. Deinlein, I. Zwiener, A. Faldum, J. Kuehl, K. KRAMER, N. P. -Taskar, P. Zanzonico, J. L. Humm, S. L. Wolden, N.-K. V. Cheung, S. Venkataraman, I. Alimova, P. Harris, D. Birks, I. Balakrishnan, A. Griesinger, N. K. Foreman, R. Vibhakar, A. Margol, N. Robison, J. Gnanachandran, L. Hung, R. Kennedy, M. Vali, G. Dhall, J. Finlay, A. Erdrich-Epstein, M. Krieger, R. Drissi, M. Fouladi, F. Gilles, A. Judkins, R. Sposto, S. Asgharzadeh, A. Peyrl, M. Chocholous, S. Holm, P. Grillner, K. Blomgren, A. Azizi, T. Czech, B. Gustafsson, K. Dieckmann, U. Leiss, I. Slavc, S. Babelyan, I. Dolgopolov, R. Pimenov, G. Mentkevich, S. Gorelishev, M. Laskov, A. O. von Bueren, J. Nowak, R. D. Kortmann, M. Mynarek, K. Muller, N. U. Gerber, H. Ottensmeier, R. Kwiecien, M. Yankelevich, V. Boyarshinov, I. Glekov, S. Ozerov, S. Gorelyshev, A. Popa, N. Subbotina, A. M. Martin, C. Nirschl, M. Polanczyk, R. Bell, D. Martinez, L. M. Sullivan, M. Santi, P. C. Burger, J. M. Taube, C. G. Drake, D. M. Pardoll, M. Lim, L. Li, W.-G. Wang, J.-X. Pu, H.-D. Sun, R. Ruggieri, M. H. Symons, M. I. Vanan, S. Bolin, S. Schumacher, R. Zeid, F. Yu, N. Vue, W. Gibson, B. Paolella, F. J. Swartling, M. W. Kieran, J. E. Bradner, O. Maher, S. Khatua, N. Tarek, W. Zaky, T. Gupta, S. Mohanty, S. Kannan, R. Jalali, E. Kapitza, D. Denkhaus, A. z. Muhlen, D. G. van Vuurden, M. Garami, J. Fangusaro, T. B. Davidson, M. J. G. da Costa, J. Sterba, S. C. Clifford, J. L. Finlay, R. Schmidt, J. Felsberg, H. Skladny, F. Cremer, G. Reifenberger, R. Kunder, E. Sridhar, A. A. Moiyadi, A. Goel, N. Goel, N. Shirsat, R. Othman, L. Storer, I. Kerr, B. Coyle, N. Law, M. L. Smith, M. Greenberg, S. Laughlin, D. Malkin, F. Liu, I. Moxon-Emre, N. Scantlebury, A. Nasir, D. Onion, A. Lourdusamy, A. Grabowska, Y. Cai, T. Bradshaw, R. S. S. de Medeiros, A. Beaugrand, S. Soares, S. Epelman, W. Wang, M. Sultan, R. J. Wechsler-Reya, M. Zapatka, B. Radlwimmer, D. Alderete, L. Baroni, F. Lubinieki, F. Auad, M. L. Gonzalez, W. Puya, P. Pacheco, O. Aurtenetxe, A. Gaffar, L. Gros, O. Cruz, C. Calvo, N. Shinojima, H. Nakamura, J.-i. Kuratsu, A. Hanaford, C. Eberhart, T. Archer, P. Tamayo, S. Pomeroy, E. Raabe, K. De Braganca, S. Gilheeney, Y. Khakoo, K. Kramer, S. Wolden, I. Dunkel, R. R. Lulla, J. Laskowski, S. Goldman, V. Gopalakrishnan, D. Shih, X. Wang, C. Faria, C. Raybaud, U. Tabori, J. Rutka, S. Jacobs, F. De Vathaire, I. Diallo, D. Llanas, C. Verez, F. Diop, A. Kahlouche, S. Puget, E. Thompson, E. Prince, V. Amani, P. Sin-Chan, M. Lu, C. Kleinman, T. Spence, D. Picard, K. C. Ho, J. Chan, J. Majewski, N. Jabado, P. Dirks, A. Huang, J. R. Madden, A. M. Donson, D. M. Mirsky, A. Dubuc, S. Mack, D. Gendoo, B. Luu, T. MacDonald, T. Van Meter, S. Croul, A. Laureano, W. Brugmann, C. Denman, H. Singh, H. Huls, J. Moyes, D. Sandberg, L. Silla, L. Cooper, and D. Lee
- Subjects
Oncology ,Abstracts ,Cancer Research ,medicine.medical_specialty ,Cns pnet ,business.industry ,Internal medicine ,Meta-analysis ,medicine ,Neurology (clinical) ,business - Published
- 2014
12. The Role of Steroid Hormones in Sex Recognition during Spawning Behaviour of the Goldfish, Carassius auratus L
- Author
-
F Yamazaki and K Watanabe
- Subjects
integumentary system ,urogenital system ,parasitic diseases ,lcsh:Q ,sense organs ,lcsh:Science ,reproductive and urinary physiology - Abstract
The Role of Steroid Hormones in Sex Recognition during Spawning Behaviour of the Goldfish, Carassius auratus L
- Published
- 2015
13. Motor learning changes the lipid profile of frontal white matter
- Author
-
Hiroaki Wake, Daisuke Kato, I. Yao, Y. Tsuji, Y. Tachibana, T. Toda, F. Yamazaki, M. Shinohara, and M. Setou
- Subjects
Neurology ,medicine.diagnostic_test ,Frontal white matter ,medicine ,Neurology (clinical) ,Biology ,Motor learning ,Lipid profile ,Neuroscience - Published
- 2017
14. Comparison of Bactericidal Effects of Commonly Used Antiseptics against Pathogens Causing Nosocomial Infections
- Author
-
F. Yamazaki, Y. Asano, T Yasuda, H Takada, S. Kawaguchi, Y. Yoshimura, J. Iriyama, M. Ito, and S. Ishigo
- Subjects
biology ,medicine.drug_class ,Dermatology ,biology.organism_classification ,Enterobacteriaceae ,Microbiology ,chemistry.chemical_compound ,Stenotrophomonas maltophilia ,chemistry ,Antiseptic ,Sodium hypochlorite ,Serratia marcescens ,medicine ,Bacteria ,Antibacterial agent ,Pseudomonadaceae - Abstract
Opportunistic infections caused by gram-negative rods (GNR), conventionally regarded as organisms with low or no pathogenicity, and intractable infections caused by various resistant organisms pose a great problem now. In view of this, we determined the bactericidal effects of 5 commonly used disinfectants using as the test strains Xanthomonas maltophilia and Serratia marcescens, chosen among other GNR since they often cause nosocomial infections. Regarding the bactericidal activities against X. maltophilia and S. marcescens, both sensitive strains and resistant strains were killed within 20 s of exposure to povidone-iodine and sodium hypochlorite. With chlorhexidine, 1 strain each of both species was not killed within 10 min of exposure at a concentration of 0.2%. Both sensitive strains and resistant strains of X. maltophilia were killed within 20 s of exposure to benzalkonium at 0.02%, while a concentration of 0.1% was required for benzalkonium to kill S. marcescens within 20 s. With Tego-51, both sensitive strains and resistant strains of X. maltophilia were killed within 20 s at 0.02%, while 1 strain of S. marcescens was not killed within 20 s at a concentration of 0.1%. In the use of disinfectants, comparative bactericidal effects of various disinfectants against clinical isolates should be taken into consideration.
- Published
- 1997
15. Contents, Vol. 195, Supplement 2, 1997
- Author
-
Y. Ihara, S. Oda, S. Ishigo, K. Sato, T. Miyai, I. Matsumoto, T. Kitamura, I.A. Adamietz, K. Oizumi, J. Kumazawa, G. Erdos, Y. Takahashi, H.-D. Boettcher, Y. Yoshimura, N. Hayakawa, R. Niedner, S. Kawahara, T. Kurosaki, A.E. van der Merwe, O. Morita, A. Yamada, Y. Nezu, W. Behrens-Baumann, T. Rikimaru, M. Kondo, K. Yamada, K. Yanagi, H. Kuroki, T. Kunisada, D. Michel, A. Simmons, R. Kawana, Y. Furuya, H. Takada, Erica L. Eason, M. Kanazawa, B. König, O. Nakagomi, K. Sugimoto, S. Chiba, O. Hara, D.G. MacLellan, A. Hoshioka, R. Rahn, V. Schaefer, S. Kawaguchi, M. Arita, K. Reimer, K. Takahashi, W. Fleischer, T. Matsumoto, N. Yoshihara, G.A. Zäch, P. Burkhard, Y. Yoshida, M. Ermini, M. Sakumoto, S. Kondo, A. Lanzendörfer, K. Shindo, Y. Nakagawa, H. Schreier, T. Arata, B. Lanker Klossner, M. Ito, N. Ishiwada, Y. Asano, T. Shiraishi, R. Namba, F. Yamazaki, M. Kamitani, K. Nobukuni, R. Oka, W. König, H.-R. Widmer, T. Yasuda, B. Brögmann, T. Toba, T. Hayabara, H. Hoekstra, J. Iriyama, H. Gümbel, H. Abe, and F. Frey
- Subjects
Dermatology - Published
- 1997
16. Contents Vol. 16, 2003
- Author
-
P. Boone, S. Hammer, F. Benech-Kieffer, Hidekazu Yamada, F. Yamazaki, A.-C. Goydadin, H. Brocvielle, C. Leclerc, Howard I. Maibach, Monika Schäfer-Korting, T. Yudate, P. Humbert, Jens-Uwe Grundmann, Harald Gollnick, F. Broly, Masaharu Matsukura, Gerhard J. Nohynek, Ulrike Blume-Peytavi, I. Brinkmann, R.G. Ramirez, Hongbo Zhai, Peter Elsner, J.-P. Kantelip, Len Roza, Uta-Christina Hipler, Jacques Leclaire, Ingrid Wiswedel, W.J.A. Meuling, A. Yajima, T. Tezuka, Tobias W. Fischer, U. Münster, Christel C. Müller-Goymann, D. Hirsch, and Patrice Muret
- Subjects
Pharmacology ,Biochemistry ,Physiology ,Philosophy ,Dermatology ,General Medicine - Published
- 2003
17. Sodium Percarbonate: A Convenient Reagent for Oxidative Cleavage of A-Diketones
- Author
-
D. T. C. Yang, T. T. Evans, F. Yamazaki, G. W. Kabalka, and C. Narayanna
- Subjects
chemistry.chemical_compound ,chemistry ,Reagent ,Organic Chemistry ,Organic chemistry ,Sodium percarbonate ,Oxidative cleavage ,humanities - Abstract
Sodium percarbonate has been found to be a mild and effective reagent for the oxidative cleavage of a-diketones to carboxylic acids
- Published
- 1993
18. Magnetic resonance imaging of the temporomandibular joint in the mouse
- Author
-
Toshirou Kondoh, Ko Ito, K. Takahashi, Y. Ohashi Y. Seo, and F. Yamazaki
- Subjects
medicine.anatomical_structure ,Nuclear magnetic resonance ,Otorhinolaryngology ,medicine.diagnostic_test ,business.industry ,Medicine ,Surgery ,Magnetic resonance imaging ,Oral Surgery ,business ,Temporomandibular joint - Published
- 2014
19. ChemInform Abstract: Sodium Percarbonate: A Convenient Reagent for Oxidative Cleavage of . alpha.-Diketones
- Author
-
D. T. C. Yang, F. Yamazaki, G. W. Kabalka, T. T. Evans, and C. Narayanna
- Subjects
chemistry.chemical_compound ,chemistry ,Reagent ,Alpha (ethology) ,General Medicine ,Sodium percarbonate ,Oxidative cleavage ,Medicinal chemistry - Published
- 2010
20. Omentopexy for Revascularization of Free Tracheal Grafts in Rats
- Author
-
Hiromi Wada, Yutaka Takahashi, Kenji Inui, Shigeki Hitomi, F. Yamazaki, T. Fukuse, Toshiki Hirata, Kotaro Muro, Hiroyasu Yokomise, and Takashi Hirai
- Subjects
Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Time Factors ,medicine.medical_treatment ,Revascularization ,Epithelium ,Omentopexy ,Abdominal wall ,Peritoneal cavity ,medicine ,Animals ,Mucosal epithelium ,Neovascularization, Pathologic ,business.industry ,Regeneration (biology) ,respiratory system ,Rats, Inbred F344 ,Rats ,Surgery ,Trachea ,medicine.anatomical_structure ,Cardiology and Cardiovascular Medicine ,business ,Omentum - Abstract
In rats, we examined the effect of an omentum wrapping on the vascularization of the trachea and on regeneration of the mucosal epithelium in the very early stage after free tracheal grafting. Two pieces of trachea were obtained from each donor rat. One piece was transplanted into the peritoneal cavity of the recipient rat and wrapped with omentum. The other piece was transplanted subcutaneously into the abdominal wall, without omentopexy. Recipients were sacrificed at random on days 1, 2, 3, and 4 after operation (5 rats/day). The increase of blood vessels rose significantly earlier in the omentopexy tracheas than in those without omentopexy (p less than 0.01), with all the former showing a normal ciliated, columnar epithelium in the membranous region of the trachea on day 4, accompanied by excellent epithelial regeneration in the cartilaginous region. These results suggest that omentopexy causes revascularization to occur earlier and to be completed in a shorter time, and that it also promotes epithelial regeneration following free tracheal grafting.
- Published
- 1992
21. A reevaluation of heparin requirements for cardiopulmonary bypass
- Author
-
Paulo Francisco Guerreiro Cardoso, G.A. Patterson, Michael F.X. Glynn, F. Yamazaki, H.-J. Schaefers, Shaf Keshavjee, L.S. Wang, Chia-Ming Hsieh, and Joel D. Cooper
- Subjects
Pulmonary and Respiratory Medicine ,Oxygenators ,Membrane oxygenator ,medicine.diagnostic_test ,medicine.drug_class ,business.industry ,Anticoagulant ,Activated clotting time ,Heparin ,law.invention ,Whole Blood Coagulation Time ,law ,Anesthesia ,medicine ,Cardiopulmonary bypass ,Surgery ,Cardiology and Cardiovascular Medicine ,business ,Oxygenator ,medicine.drug - Abstract
We wished to determine if reduction in the standard heparin administration for cardiopulmonary bypass could be accomplished safely with the use of membrane oxygenators. An experimental study was designed to evaluate two different heparin administration protocols for cardiopulmonary bypass with hollow-fiber membrane oxygenators. Two groups of six pigs were submitted to hypothermic cardiopulmonary bypass (28 degrees C) for 3 hours, then rewarmed, decannulated, and reassessed after 1 hour. In group I (control) heparin was administered to maintain the activated clotting time in excess of 450 seconds; in group II activated clotting time was maintained between 250 and 300 seconds. The mean total heparin administered was 41,000 units in group I and 25,000 units in group II. Concentration of coagulation factors II, V, and VIII, fibrinogen, and platelet count were determined before, during, and 1 hour after bypass. No significant difference in any of these coagulation parameters was observed between the groups. The performance of the oxygenators was similar in both groups, with no evidence of thrombosis. Thus reduced heparin administration, enough to keep activated clotting time between 250 and 300 seconds, was not related either to major coagulation factors and platelet consumption or to derangements in the oxygenator's performance.
- Published
- 1991
22. [The third repair for pseudoaneurysm following Bentall procedure: report of a case]
- Author
-
H, Masumoto, M, Shimamoto, F, Yamazaki, M, Nakai, S, Fujita, and T, Itonaga
- Subjects
Heart Valve Prosthesis Implantation ,Male ,Reoperation ,Blood Vessel Prosthesis Implantation ,Postoperative Complications ,Heart Valve Prosthesis ,Humans ,Aneurysm, False ,Aged ,Blood Vessel Prosthesis - Abstract
A 77-year-old male, who had undergone the Bentall procedure 27 years ago, was admitted to our hospital for the repair of postoperative pseudoaneurysm. This was the 3rd repair, and the pseudoaneurysm was close to the sternum. Total extracorporeal circulation was established with femorofemoral cannulation and sternotomy was performed under deep hypothermia. During sternotomy, we encountered massive hemorrhage due to injury of the aortic graft. We coped effectively with the situation utilizing temporary circulatory arrest. Aortic graft reimplantation was performed under continuous retrograde cerebral perfusion. Collapse of the suture line of the left coronary orifice was recognized and was reconstructed. The patient was discharged uneventfully on the 26th postoperative day.
- Published
- 2007
23. [Clinical outcome of aortic valve replacement with 19-mm prosthetic valve in elderly patients]
- Author
-
S, Fujita, M, Shimamoto, F, Yamazaki, M, Nakai, K, Takeuchi, H, Masumoto, T, Iwakura, T, Itonaga, and H, Motoyama
- Subjects
Aged, 80 and over ,Bioprosthesis ,Heart Valve Prosthesis Implantation ,Male ,Survival Rate ,Aortic Valve ,Heart Valve Prosthesis ,Prosthesis Fitting ,Aortic Valve Insufficiency ,Humans ,Female ,Aortic Valve Stenosis ,Aged - Abstract
From 1979 to June 2005, 90 patients aged 65 or older underwent aortic valve replacement with 19-mm prosthetic valve. They were 84 women and 6 men, with a mean age of 74. The mean body surface area was 1.35 m2. Bioprosthetic valves were implanted in 77 patients (85.6%). In-hospital mortality was 2.2% (2 of 90). There were 13 late deaths. New York Heart Association (NYHA) functional class improved to class I in most of survivors. Survival rates for 5 and 10 years were 84.9 and 71.2%, respectively. The outcome of aortic valve replacement with 19-mm prosthetic valve in elderly patients was excellent.
- Published
- 2006
24. [Surgical treatment of Marfan syndrome; analysis of the patients required multiple surgical interventions]
- Author
-
F, Yamazaki, M, Shimamoto, S, Fujita, M, Nakai, A, Aoyama, F, Chen, T, Nakata, and T, Yamada
- Subjects
Adult ,Male ,Reoperation ,Time Factors ,Adolescent ,Aorta, Thoracic ,Middle Aged ,Prognosis ,Aortic Aneurysm ,Marfan Syndrome ,Radiography ,Aortic Dissection ,Blood Vessel Prosthesis Implantation ,Humans ,Female ,Aged ,Follow-Up Studies - Abstract
Without treatment, the life expectancy of patients with Marfan syndrome is reduced by the associated cardiovascular abnormalities. In this study, we reviewed our experience of the patients with Marfan syndrome who required multiple surgical interventions to identify the optimal treatment for these patients. Between January 1986 and December 2000, 44 patients with Marfan syndrome were operated on at Shizuoka City Hospital (SCH). Among them, 10 patients (22.7%) underwent multiple surgical interventions. There were 5 male and 5 female patients with a mean age of 40.6 +/- 16.1 years at the initial surgery. Only one patient was operated on at another hospital for his first, second, and third operations. His fourth operation was carried out at SCH. The remaining 9 patients underwent a total of 14 additional surgical procedures at SCH. Computed tomography (CT) scans were taken every 6 months postoperatively, and aortic diameter greater than 60 mm was considered as the indication for the additional surgery. There were no early death and one late death. The causes of additional surgery were enlargement of true aneurysm in 6, enlargement of residual dissection in 4, new dissection in 4, false aneurysm at the coronary anastomosis of Bentall procedure in 1. In 9 patients, both ascending and descending aorta were replaced. Among these 9 patients, only 3 patients underwent total arch replacement, and remaining 6 patients had their arch left in place with or without dissection. Our current strategy of the treatment of Marfan patients with acute type A dissection is total arch replacement with an elephant trunk at the initial emergent surgery.
- Published
- 2002
25. [Long-term results after surgery for aortic arch nondissection aneurysm]
- Author
-
M, Nakai, M, Shimamoto, F, Yamazaki, S, Fujita, A, Aoyama, T, Chin, T, Nakata, and T, Yamada
- Subjects
Aged, 80 and over ,Male ,Extracorporeal Circulation ,Aortic Aneurysm, Thoracic ,Aorta, Thoracic ,Middle Aged ,Perfusion ,Survival Rate ,Blood Vessel Prosthesis Implantation ,Hypothermia, Induced ,Cerebrovascular Circulation ,Humans ,Female ,Aged - Abstract
Between 1990 and August 2001, 109 patients were treated surgically for nondissection fusiform or saccular aortic arch aneurysm. Fifteen patients were emergent. There were 89 male and 20 female patients (mean 71.7 +/- 6, range 49 to 84). Eight patients underwent hemiarch replacement, 57 total arch replacement, 44 distal arch replacement, which were performed with the aid of hypothermic extracorporeal circulation with antegrade selective cerebral perfusion or retrograde cerebral perfusion. The early mortality was 8.5% with elective operations and 53.3% with emergent operations. The incidence of post operative permanent neurological dysfunction was 12.8% with elective operations and 46.7% with emergent operations. The 5-year and 10-year survival rate including in-hospital deaths was 52 +/- 6% and 29 +/- 9%. The 5-year event free rate was 89 +/- 5%.
- Published
- 2002
26. [A case of disseminated intravascular coagulopathy (DIC) and multiple organ failure (MOF) after ingestion of hydrochloric acid]
- Author
-
Y, Niki, K, Minakuchi, A, Takasu, T, Nakamura, S, Inada, F, Yamazaki, and H, Mori
- Subjects
Adult ,Suicide ,Multiple Organ Failure ,Humans ,Female ,Hydrochloric Acid ,Disseminated Intravascular Coagulation ,Acidosis - Abstract
Ingestion of caustic materials causes systemic damages and requires treatment in an intensive care unit. This report presents a case of disseminated intravascular coagulopathy (DIC) and multiple organ failure after ingestion of hydrochloric acid in an attempted suicide. The patient was admitted to the emergency ward within 1 hr after ingestion of 60 ml of 35% hydrochloric acid. Initial blood examination suggested hemolysis without anemia or thrombocytopenia. Arterial blood gas analysis exhibited evident metabolic acidosis with hypoxia. Two hours after ingestion, severe hemolysis, anemia, thrombocytopenia emerged with abnormal results from clotting and fiblinolysis tests, and a diagnosis of DIC was made. Subsequently, conjugate deviation and severe bleeding diathesis appeared. No evidence for gastrointestinal bleeding and brain hemorrhage was obtained in our abdominal echography and brain computed tomography, respectively. In spite of vigorous suppurative therapy including transfusion of blood, fresh frozen plasma, and catecholamines, the patient expired 29 hrs after ingestion. Autopsy was not carried out. Rapid progressive DIC as an acute complication of acid ingestion must be born in mind.
- Published
- 2002
27. [Analysis of chimerism in patients with hematologic malignancies after allogeneic hematopoietic stem cell transplantation]
- Author
-
T, Furukawa, S, Hashimoto, K, Inano, F, Yamazaki, H, Takeda, T, Kakihara, T, Yano, T, Abe, W, Higuchi, K, Toba, M, Takahashi, T, Koike, and Y, Aizawa
- Subjects
Adult ,Transplantation Chimera ,Adolescent ,Tandem Repeat Sequences ,Child, Preschool ,Hematologic Neoplasms ,Hematopoietic Stem Cell Transplantation ,Graft vs Host Disease ,Humans ,Infant ,Middle Aged ,Child - Abstract
Serial monitoring of chimerism after allogeneic hematopoietic stem cell transplantation (HSCT) can be performed easily and rapidly using PCR-based assays analyzing informative tandem repeat genetic markers. Sequential analysis of individual chimerism status was performed in 34 patients who underwent myeloablative allo-HSCT using a commercial multiplex short tandem repeat (STR) kit. Mixed chimerism (MC) was found in 14 of the patients for more than one month. The incidence of MC seemed to be dependent on the type of disease or pretransplantation regimen. There was no significant difference in relapse rates between MC and complete donor chimerism (CC) in all patients. However, the relapse rate was significantly higher in MC than in CC among patients with acute leukemia. The severity of acute graft-versus-host disease (aGVHD) was significantly reduced in the patients with MC. Most of the MC patients with hematologic malignancies had transient mixed T-lymphoid chimerism, and CC was achieved within 6 months after HSCT in such cases. Patients with MC beyond 6 months after HSCT and patients with reappearance of autologous signals (MC after CC) may have an enhanced risk of relapse.
- Published
- 2001
28. Increased antibody levels to desmogleins 1 and 3 after administration of carbamazepine
- Author
-
T, Yoshimura, M, Seishima, K, Nakashima, Y, Yasuhara, S, Adachi, M, Kawaguchi, N, Minoura, T, Nakao, J, Kobayashi, and F, Yamazaki
- Subjects
Adult ,Male ,Adolescent ,Desmoglein 3 ,Desmoglein 1 ,Analgesics, Non-Narcotic ,Middle Aged ,Cadherins ,Carbamazepine ,Case-Control Studies ,Child, Preschool ,Humans ,Anticonvulsants ,Female ,Pemphigus ,Aged - Abstract
Desmoglein (Dsg) 1 and Dsg3 are recognized as the autoantigens in pemphigus foliaceus and pemphigus vulgaris. Pemphigus-like syndromes have been reported to occur in individuals after exposure to a variety of drugs, but pemphigus caused by carbamazepine is not common. We found that anti-Dsg1 and anti-Dsg3 antibody titres were increased in three individuals administered carbamazepine. Antibody titres against Dsgs 1 and 3 were measured by enzyme-linked immunosorbent assay (ELISA). Of 42 serum samples (25 patients administered carbamazepine, eight patients administered valproic acid and nine healthy volunteers) tested by ELISA, three patients administered carbamazepine showed positive reactivity against both Dsg1 and Dsg3. The patient with the highest titre against Dsg1 and Dsg3 (the index values of anti-Dsg1 and anti-Dsg3 were 79.3 and 86.4, respectively) was a 23-year-old woman (Case 1). The other two patients with positive reactivity were a 5-year-old boy (Case 2) and a 65-year-old man (Case 3). In addition, indirect immunofluorescence study showed intercellular antibodies to the cell surface of the whole epidermis with a titre of 1 : 64 in Case 1 and 1 : 2 in Cases 2 and 3. However, no skin or mucosal involvement was found in any of these cases. There was no difference in the serum concentrations of carbamazepine between the three positive cases and the 22 negative cases of carbamazepine administration. From these facts, the lack of skin diseases may be explained by relatively low values of anti-Dsg 1 and 3 antibodies in Cases 2 and 3. However, it cannot be excluded that undefined exogenous and/or endogenous factors are involved in an outbreak of pemphigus. Furthermore, these findings might be helpful for preventing susceptible individuals from exposure to the suspect drugs.
- Published
- 2001
29. Pemphigus of the eyelids
- Author
-
M, Seishima, Z, Oyama, H, Shimizu, Y, Naganawa, T, Yoshimura, and F, Yamazaki
- Subjects
Desmoglein 3 ,Desmoglein 1 ,Prednisolone ,Anti-Inflammatory Agents ,Fluorescent Antibody Technique ,Enzyme-Linked Immunosorbent Assay ,Middle Aged ,Cadherins ,Diagnosis, Differential ,Eyelid Diseases ,Humans ,Female ,Dermatitis, Perioral ,Pemphigus - Abstract
We report the case of a 56-year-old woman who presented with a 2-month history of widespread oral erosion and a 3-day history of small papules on the lower eyelids. No other skin involvement was found. Histopathological examination revealed suprabasal cleft and acantholysis in the lower epidermis of the papule on the lower eyelid and in the lower mucous membrane of the oral mucosa. Intercellular deposits of IgG and C3 were seen in the whole epidermis of the specimen from the papule on the right lower eyelid by direct immunofluorescence study. These deposits were also observed in the biopsy specimen from erosion on the left buccal membrane. Indirect immunofluorescence study using normal human skin as a substrate showed intercellular antibodies directed to the cell surface of the whole epidermis with a titer of 1:40. The titers of antibodies to desmoglein 3 and 1 were 118 and 25.9, respectively, by enzyme-linked immunosorbent assay. The patient was treated with an oral administration of prednisolone (0.75 mg/kg/day) for 9 days, which improved the skin eruptions and oral erosion. The dose of prednisolone was gradually tapered and it took 10 weeks to cease this treatment. These findings suggest that this patient is an unusual case of pemphigus vulgaris (mucosal dominant type) diagnosed from the clinical and histopathological findings, with positive antibodies to desmoglein 3 and 1.
- Published
- 2001
30. Continuous monitoring of change in hemodilution during water immersion in humans: effect of water temperature
- Author
-
F, Yamazaki, Y, Endo, R, Torii, S, Sagawa, and K, Shiraki
- Subjects
Adult ,Erythrocyte Indices ,Male ,Time Factors ,Osmolar Concentration ,Temperature ,Water ,Capillary Resistance ,Blood Viscosity ,Hematocrit ,Hemorheology ,Immersion ,Humans ,Plasma Volume ,Fluid Shifts ,Weightlessness Simulation ,Monitoring, Physiologic - Abstract
The present study was designed to examine whether water temperature during head-out immersion (HOI) modifies hemodilution dynamics.We made continuous measurements of blood density (rho(b)) during HOI at 3 different water temperatures; the lower critical (32 degrees C), neutral (34.5 degrees C), and upper critical (36 degrees C) temperatures in 6 healthy male volunteers. Blood was withdrawn continuously from the antecubital vein for measurement of rho(b) during 60 min of water immersion with a 10-min control period before the immersion. The density was measured with the mechanical oscillator technique. Hematocrit (Hct), plasma density (rho(p)), and osmolality were measured at 5-min intervals. Erythrocyte density (rho(e)) was calculated from rho(b), rho(p) and Hct. Cardiac output and BP were measured to calculate total peripheral resistance.Hct, rho(b), and rho(p) decreased rapidly in the first 20-25 min of immersion and were maintained at a reduced level during immersion. Plasma volume calculated from rho(p) and Hct increased with the rho(b) reduction. These immersion-induced changes were independent of these water temperatures. Plasma osmolality and rho(e) remained constant throughout the experimental period in the three temperature conditions, indicating that the increase in plasma volume and hence hemodilution was induced by an isotonic fluid shift from extravascular space. The total peripheral resistance increased inversely in proportion to the water temperature during HOI.In the present condition, water temperature did not modify the net transcapillary fluid transfer during HOI in the presence of the temperature dependent increase in vascular tone.
- Published
- 2000
31. Vulnerability Functions for Japanese Buildings based on Damage Data from the 1995 Kobe Earthquake
- Author
-
F. Yamazaki and O. Murao
- Published
- 2000
32. Valvular heart diseases. Results of the surgical treatment for valvular heart disease. The impact of reoperation on the survival
- Author
-
F. Yamazaki
- Subjects
medicine.medical_specialty ,business.industry ,Internal medicine ,valvular heart disease ,medicine ,Cardiology ,Surgical treatment ,business ,medicine.disease - Published
- 1991
33. Chromosomal localization and heterochromatin association of ribosomal RNA gene loci and silver-stained nucleolar organizer regions in salmonid fishes
- Author
-
A, Fujiwara, S, Abe, E, Yamaha, F, Yamazaki, and M C, Yoshida
- Subjects
Silver Staining ,Base Sequence ,Species Specificity ,RNA, Ribosomal ,Salmon ,Heterochromatin ,Nucleolus Organizer Region ,Animals ,Chromosome Mapping ,DNA Probes ,In Situ Hybridization, Fluorescence ,Chromosome Banding ,DNA Primers - Abstract
Ribosomal RNA gene (rDNA) loci, including those of nucleolus-forming 18S, 5.8S and 28S (major) and non-nucleolus-forming 5S (minor) rDNA, were assigned using fluorescence in situ hybridization (FISH) to the embryonic chromosomes of rainbow trout (Oncorhynchus mykiss), masu salmon (O. masou), brook trout (Salvelinus fontinalis) and Japanese huchen (Hucho perryi). In these species, the minor rDNA loci were located basically on 2-4 chromosome pairs, whereas the major rDNA loci were found essentially on one chromosome pair, except for the brook trout. Its major rDNA loci were dispersed on about half of the chromosome complement, showing a considerable interindividual variation in the number and location. The major and minor rDNA loci were separated onto different chromosomes in the examined species, except for the rainbow trout, in which one chromosome pair had tandemly aligned minor and major rDNA loci. Chromosome regions containing both kinds of rDNA loci in each species were found to be stained with C-banding, showing an association of these loci with heterochromatin. Comparison of the assigned major rDNA loci and sequentially detected silver (Ag)-stained nucleolar organizer regions (AgNORs) in all the species revealed a considerable polymorphism in the number and size of AgNORs among or within those loci, suggesting a possible inter- or intralocus inactivation of the major rDNAs.
- Published
- 1998
34. [Late results of acute aortic dissection: analysis of the patients longer than five years after the operation]
- Author
-
F, Yamazaki, M, Shimamoto, M, Nakai, T, Kobayashi, H, Sahara, N, Miyamoto, A, Ohsumi, and T, Kohno
- Subjects
Adult ,Male ,Time Factors ,Aortic Aneurysm, Thoracic ,Middle Aged ,Prognosis ,Survival Rate ,Aortic Dissection ,Blood Vessel Prosthesis Implantation ,Acute Disease ,Humans ,Female ,Survivors ,Cardiac Surgical Procedures ,Aged - Abstract
Between 1985 and 1992, 28 patients of acute type A aortic dissection were operated on at our department. Our surgical strategy for this disease is "limited aortic resection", that is to avoid replacement of the entire arch except for the patients with arch tear that cannot be resected without total arch replacement. There were one operative mortality due to post transfusion GVHD, and ten late mortality (rupture of the residual dissecting aneurysm 3; complication of the late reoperation 3; cerebrovascular disease 2; pulmonary infection 2). Actuarial survival rate of all cases is 92.9%, 62.9%, and 58.4% at 1, 5, and 10 years, respectively. Comparing the patients whose primary tear was resected or not resected, there was no difference in the rate of residual dissection (12/16, 75% vs 5/6, 83.3%; primary tear resected vs not resected), the rate of late reoperation (3/16, 18.8% vs 1/6, 16.7%), nor actuarial survival rate (90.5% vs 100%, 66.7% vs %, 53.6% vs 71.4%, at 1, 5, 10 years, respectively). There were three cases with Marfan's syndrome, and all three cases died of the rupture of the residual dissection. We will follow the policy of the "limited aortic resection" unless the operative mortality of the entire arch replacement is proved as good as that of the ascending or hemiarch replacement. Because of the poor late results of the patients with Marfan's syndrome, entire arch replacement at the initial surgery and aggressive reoperation for the residual dissection is necessary.
- Published
- 1998
35. Assessment of cardiac autonomic nervous activities during heliox exposure at 24 atm abs
- Author
-
F, Yamazaki, K, Shiraki, S, Sagawa, Y, Endo, R, Torii, H, Yamaguchi, M, Mohri, and Y C, Lin
- Subjects
Adult ,Male ,Heart Rate ,Diving ,Bradycardia ,Humans ,Heart ,Vagus Nerve ,Middle Aged ,Autonomic Nervous System ,Circadian Rhythm - Abstract
This experiment was designed to examine the involvement of the autonomic nervous system in the production of hyperbaric bradycardia.Four male divers were exposed to a He-O2 (heliox) environment at 24 atmosphere absolute (atm abs) for 7 d. The heart rate (HR) and respiratory rate were recorded at rest in the morning (0700 h) and at night (2230 h) on 1 d during a 5-d predive control, 2 d during a 7-d saturation dive at 24 atm abs, 2 d during decompression, and on 1 d during a 4-d postdive period. Cardiac sympathetic and parasympathetic activities were estimated by using a spectral analysis of the variability of R-R intervals.The morning HR did not fluctuate throughout the experimental days. The night time HR decreased (p0.05) by 11.8% on the first day at 24 atm abs compared with that of the predive control. The bradycardia diminished gradually and returned to the predive level with continued exposure at 24 atm abs. The high-frequency power of the cardiac variability, an index of cardiac parasympathetic activity, increased (p0.05) only in the first night at 24 atm abs, whereas the low-frequency power and a ratio of low- to high-frequency power, an index of cardiac sympathetic activity, were unchanged.The present results suggest that an increased parasympathetic activity rather than a decrease in the sympathetic activity is responsible for the bradycardia on exposure to heliox dry saturation dive at 24 atm abs. The mechanism of the gradual disappearance of the bradycardia is unknown, but perhaps it may be related to the development of cardiovascular deconditioning.
- Published
- 1998
36. Modulation of Th1- and Th2-like cytokine production from mitogen-stimulated human peripheral blood mononuclear cells by phosphodiesterase inhibitors
- Author
-
T, Yoshimura, T, Nagao, T, Nakao, S, Watanabe, E, Usami, J, Kobayashi, F, Yamazaki, H, Tanaka, N, Inagaki, and H, Nagai
- Subjects
Phosphodiesterase Inhibitors ,Pyridones ,Interleukins ,Adrenergic beta-Agonists ,In Vitro Techniques ,Th1 Cells ,Pyrrolidinones ,Interferon-gamma ,Th2 Cells ,Bucladesine ,Theophylline ,Leukocytes, Mononuclear ,Humans ,Mitogens ,Rolipram ,Milrinone - Abstract
1. Effects of phosphodiesterase (PDE) inhibitors on the production of IFN-gamma, IL-2, IL-4 and IL-5 by phytohemagglutinin (PHA)-stimulated human peripheral blood mononuclear cells (PBMC) were investigated. In addition, we investigated the effects of dibutyrylcyclic AMP (dbcAMP) and a beta-adrenoceptor agonist on production of these cytokines. 2. Type IV, type III and nonselective PDE inhibitors were effective at inhibiting the production of IFN-gamma and IL-2 production in a dose-dependent manner. In contrast, IL-4 and IL-5 production was inhibited by only the highest concentration of type IV inhibitor, and other agents had no effect on the production. 3. Similarly, dbcAMP inhibited the production of IFN-gamma and IL-2 more potently than IL-4 and IL-5. 4. The addition of a beta-adrenoceptor agonist increased the inhibitory effect of PDE inhibitors tested on the production of IFN-gamma and IL-2. 5. These results indicate that PDE inhibitors or cAMP-elevating agents modulate Th1 cytokine more effectively than Th2 cytokine production.
- Published
- 1998
37. [Surgical treatment of thoracic aorta for elderly patient]
- Author
-
M, Nakai, M, Shimamoto, F, Yamazaki, M, Okiyama, H, Sahara, N, Miyamoto, A, Osumi, and S, Ito
- Subjects
Male ,Aortic Aneurysm, Thoracic ,Aortic Rupture ,Age Factors ,Aorta, Thoracic ,Middle Aged ,Survival Rate ,Aortic Dissection ,Treatment Outcome ,Elective Surgical Procedures ,Acute Disease ,Humans ,Female ,Emergencies ,Aged ,Retrospective Studies - Abstract
From 1986 to 1996, 237 patients underwent surgical treatment of thoracic aorta in our institute. We classified them as follows: group 1 is 41 patients older than 75: group 2 is 196 patients younger than 74. The number of patients of elective surgery, emergent surgery for acute dissection type A and emergent surgery for rupture or impending rupture were 28, 9, 4 in group 1 and 123, 47, 26 in group 2. Operative death (within 30 days) of elective surgery, emergent surgery for acute dissection type A and emergent surgery for rupture or impending rupture were 1 (3.6%, MOF), 1 (11%, liver failure), 2 (50%, brain damage) in group 1 and 8 (6.5), 3 (6.4%), 9 (35%) in group 2, respectively. Hospital deaths (after 30 days and cannot discharge) were 3 (11%), 0.1 (25%) in group 1 and 3 (2.4%), 1 (2.1%), 1 (3.8%) in group 2. There was no significant difference between two groups. Survival rate of each group were 48% and 80% for five-year survival rate. Complications in elderly patients were common (88%). Respiratory insufficiency is the most frequent (51%). Otherwise survival rate of patients who had no surgical treatment of diseased thoracic aorta was reported poor by several researches. We will perform operation for elderly patients positively if we can get agreement of patients.
- Published
- 1997
38. Effects on archery performance of manipulating metamotivational state and felt arousal
- Author
-
John H. Kerr, H. Yoshida, C. Hirata, K. Takai, and F. Yamazaki
- Subjects
Adult ,Male ,Motivation ,Adolescent ,05 social sciences ,Experimental and Cognitive Psychology ,Hedonic tone ,030229 sport sciences ,050105 experimental psychology ,Sensory Systems ,Arousal ,03 medical and health sciences ,0302 clinical medicine ,Heart Rate ,Humans ,0501 psychology and cognitive sciences ,Female ,Reversal theory ,Psychology ,Social psychology ,Internal-External Control ,Psychomotor Performance ,Sports - Abstract
This study investigated the effect of the four different combinations of metamotivational state and felt arousal level (telic-low, paratelic-low, relic-high, paratelic-high) on archery performance. Skilled, average, and novice archers ( n = 28) were voluntary subjects, randomly divided into 2 groups, balanced for ability. Each group performed 2 out of the 4 experimental conditions. In this reversal theory-based field experiment, telic and paratelic metamotivational states and arousal level were manipulated prior to archery performance. The hypothesis that archery performance would be superior under telic-low arousal conditions was rejected, but evidence pointed to the possible importance of hedonic tone in performance. Post hoc analysis showed differences between combined high (telic-low, paratelic-high) and combined low (telic-low, paratelic-high) hedonic-tone groups which fell short of significance. This observation is taken as justification for further exploration of the relationship between hedonic tone and sports performance.
- Published
- 1997
39. Comparison of bactericidal effects of commonly used antiseptics against pathogens causing nosocomial infections. Part 2
- Author
-
T, Yasuda, Y, Yoshimura, H, Takada, S, Kawaguchi, M, Ito, F, Yamazaki, J, Iriyama, S, Ishigo, and Y, Asano
- Subjects
Cross Infection ,Time Factors ,Xanthomonas ,Sodium Hypochlorite ,Chlorhexidine ,Glycine ,Drug Resistance, Microbial ,Opportunistic Infections ,Serratia Infections ,Iodophors ,Anti-Infective Agents, Local ,Humans ,Benzalkonium Compounds ,Gram-Negative Bacterial Infections ,Povidone-Iodine ,Serratia marcescens ,Disinfectants - Abstract
Opportunistic infections caused by gram-negative rods (GNR), conventionally regarded as organisms with low or no pathogenicity, and intractable infections caused by various resistant organisms pose a great problem now. In view of this, we determined the bactericidal effects of 5 commonly used disinfectants using as the test strains Xanthomonas maltophilia and Serratia marcescens, chosen among other GNR since they often cause nosocomial infections. Regarding the bactericidal activities against X. maltophilia and S. marcescens, both sensitive strains and resistant strains were killed within 20 s of exposure to povidone-iodine and sodium hypochlorite. With chlorhexidine, 1 strain each of both species was not killed within 10 min of exposure at a concentration of 0.2%. Both sensitive strains and resistant strains of X. maltophilia were killed within 20 s of exposure to benzalkonium at 0.02%, while a concentration of 0.1% was required for benzalkonium to kill S. marcescens within 20 s. With Tego-51, both sensitive strains and resistant strains of X. maltophilia were killed within 20 s at 0.02%, while 1 strain of S. marcescens was not killed within 20 s at a concentration of 0.1%. In the use of disinfectants, comparative bactericidal effects of various disinfectants against clinical isolates should be taken into consideration.
- Published
- 1997
40. Predictors of atrial fibrillation after esophagectomy
- Author
-
Y. Kawaguchi, S. Sugita, T. Sato, and F. Yamazaki
- Subjects
medicine.medical_specialty ,Anesthesiology and Pain Medicine ,Esophagectomy ,business.industry ,medicine.medical_treatment ,Internal medicine ,medicine ,Cardiology ,Atrial fibrillation ,medicine.disease ,business - Published
- 2013
41. Graded exercise in three cases of heart rupture after acute myocardial infarction
- Author
-
K, Mineo, A, Takizawa, M, Shimamoto, F, Yamazaki, A, Kimura, N, Chino, and S, Izumi
- Subjects
Aged, 80 and over ,Male ,Work Capacity Evaluation ,Blood Pressure ,Middle Aged ,Exercise Therapy ,Electrocardiography ,Activities of Daily Living ,Exercise Test ,Physical Endurance ,Humans ,Female ,Aged ,Heart Rupture, Post-Infarction ,Monitoring, Physiologic - Abstract
Despite advances in the study of exercise for acute myocardial infarction (AMI) patients, few studies on exercise for post-AMI heart rupture patients have been reported. We assessed three cases of heart rupture (of the left ventricular free wall in two cases and of the ventricular septum in one case) in post-AMI patients who underwent three-graded exercise. Two of the three patients were operated on, whereas one patient was managed conservatively for heart rupture. Two of the three cases had also suffered cerebral infarction post-AMI. The exercise program was composed of three grades, slow level walking (grade 1), mild reconditioning and activities of daily living (ADL) exercises (grade 2), and optional endurance training using machines below 75% of predicted maximal heart rate (grade 3). Electrocardiograms and blood pressure were monitored during all exercises. All patients had muscle weakness, poor endurance capacity, as well as low cardiac function (28-47% of left ventricular ejection fraction). Two patients underwent grades 1 and 2 exercise programs, and the other performed grades 1, 2, and 3 exercise programs over a 3- to 10-wk period. We observed improvement in the double product, work capacity, and ADL without congestive heart failure, ischemic attack, or serious arrhythmias. However, the youngest patient, who underwent the grade 3 exercise program, died from a cardiac event 10 mo after onset of AMI. We conclude that post-AMI heart rupture patients should undergo delayed, gradual, low-level graded exercise (4-6 metabolic equivalents), with monitoring of blood pressure and electrocardiograms to improve work capacity, ADL, and the quality of life. However, daily activity and exercise intensity should be promptly supervised for those with severely deteriorated cardiac functions to prevent sudden cardiac event.
- Published
- 1995
42. [The long-term results of isolated aortic valve replacement with 19 mm prostheses]
- Author
-
T, Nakamura, M, Shimamoto, F, Yamazaki, T, Yoshimura, S, Itoi, T, Ueno, H, Oyanagi, M, Nakai, and T, Shinozaki
- Subjects
Adult ,Bioprosthesis ,Male ,Echocardiography ,Aortic Valve ,Heart Valve Prosthesis ,Humans ,Female ,Aortic Valve Stenosis ,Middle Aged ,Prognosis ,Aged ,Follow-Up Studies - Abstract
Twenty-five patients underwent isolated aortic valve replacement with 19 mm valves (8 cases with St. Jude Medical prostheses, 7 cases with Carpentier Edwards Pericardial prostheses and 10 cases with Björk-Shiley prostheses). Postoperative echocardiography revealed data as follows. Peak pressure gradients (mmHg) were 40.4 +/- 14.4 (mean +/- S.D.) in the SJM group, 23.4 +/- 9.8 in the CEP group and 50.5 +/- 16.7 in the BS group. End-diastolic left ventricular dimension in the BS group and interventricular septum thickness in the CEP group was reduced significantly. All but one case were in NYHA functional class I or II, and clinical improvement was almost satisfactory in all groups. However, in the BS group, 4 cases showed peak pressure gradients more than 50 mmHg. We conclude that 19 mm aortic prostheses in this study can provide satisfactory results. However, as for mechanical valve, it may be undesirable to choose BS prosthesis.
- Published
- 1995
43. [A case of thromboexclusion for thoracic descending aortic pseudoaneurysm with Behçet's disease]
- Author
-
T, Nakamura, M, Shimamoto, F, Yamazaki, T, Yoshimura, T, Ueno, and T, Shinozaki
- Subjects
Aortic Aneurysm, Thoracic ,Behcet Syndrome ,Humans ,Female ,Middle Aged ,Aneurysm, False ,Blood Vessel Prosthesis - Abstract
A 59-year-old woman with Behçet's disease was admitted because of hemoptysis. She had undergone resection and patch closure of a thoracic descending aortic aneurysm 6 years before this current admission. The aortography after the first operation had shown a pseudoaneurysm at the operative site. In the current operation, we performed thromboexclusion with a temporary occlusion balloon in the distal thoracic descending aorta above Adamkiewicz. The post operative course was uneventful. Postoperative angiography demonstrated exclusion of the pseudoaneurysm and the patient was discharged without recurrent hemoptysis.
- Published
- 1995
44. [Pseudoaneurysm of saphenous vein graft after CABG]
- Author
-
T, Nakamura, M, Shimamoto, F, Yamazaki, S, Fujita, T, Yoshimura, T, Ueno, and T, Shinozaki
- Subjects
Male ,Postoperative Complications ,Aortic Aneurysm, Thoracic ,Humans ,Saphenous Vein ,Coronary Artery Bypass ,Aneurysm, False ,Aged ,Angina Pectoris - Abstract
A 69-year-old man was admitted because of angina pectoris and thoracic descending aorta aneurysm. Staged operations were planned. First, he underwent CABG (coronary artery bypass grafting) with SVGs (saphenous vein grafts) to #4 PD, #7 and #12. Aprotinin was administrated to reduce blood loss. The routine postoperative graft angiography and enhanced CT showed a pseudoaneurysm in the SVG to #4 PD. We planned an elective operation of pseudoaneurysm repair and graft replacement of thoracic descending aorta. Also in this second operation, continuous infusion of aprotinin was started after the induction of anesthesia. About 30 minutes later, he suddenly fell in shock and cardiac arrest. Partial cardiopulmonary bypass was established and median sternotomy was performed. In the mediastinum, no bleeding was found. We found out a bleeding point of the SVG to #4 PD and a hemostatic clip on the right ventricule, and closed the bleeding point with suture. The cause of the pseudoaneurysm seemed to be defluxion of the hemostatic clip for a side brunch of the SVG. The cause of the preoperative shock may be an anaphylaxis to readministrated aprotinin.
- Published
- 1995
45. Subject Index Vol. 16, 2003
- Author
-
Masaharu Matsukura, F. Benech-Kieffer, H. Brocvielle, P. Humbert, C. Leclerc, Hidekazu Yamada, F. Broly, U. Münster, A.-C. Goydadin, Harald Gollnick, F. Yamazaki, T. Yudate, P. Boone, Peter Elsner, Jens-Uwe Grundmann, J.-P. Kantelip, Len Roza, D. Hirsch, Christel C. Müller-Goymann, Tobias W. Fischer, Uta-Christina Hipler, R.G. Ramirez, Patrice Muret, W.J.A. Meuling, Gerhard J. Nohynek, A. Yajima, T. Tezuka, Ulrike Blume-Peytavi, I. Brinkmann, Howard I. Maibach, Ingrid Wiswedel, Jacques Leclaire, Hongbo Zhai, S. Hammer, and Monika Schäfer-Korting
- Subjects
Pharmacology ,Index (economics) ,Physiology ,Subject (documents) ,Dermatology ,General Medicine ,Psychology ,Clinical psychology - Published
- 2003
46. [Effects of 'low dose' aprotinin in open heart surgery and its plasma concentration]
- Author
-
T, Nakamura, M, Shimamoto, F, Yamazaki, S, Fujita, T, Yoshimura, T, Ueno, H, Oyanagi, and T, Shinozaki
- Subjects
Male ,Extracorporeal Circulation ,Aprotinin ,Heart Diseases ,Heart Valve Prosthesis ,Blood Loss, Surgical ,Humans ,Blood Transfusion ,Female ,Coronary Artery Bypass ,Middle Aged ,Aged - Abstract
To determine the effects of "low dose" aprotinin in open heart surgery, we administrated it in 109 cases of CABG or prosthetic valve replacement. Patients in Group A (Aprotinin) received continuous infusion of aprotinin at the rate of 6*10(5) KIU/hr from the induction of anesthesia to the start of ECC (extra corporeal circulation), and from the end of ECC to the end of blood stanching. They also received additional 5*10(5) KIU aprotinin in ECC prime volumes. 50 patients in Group C (Control) received neither aprotinin nor placebo. Bleeding after ECC (Group A: 315.7 +/- 203.1 ml, Group C: 484.3 +/- 598.5 ml p0.01), the first 6 hours drainage (Group A: 273.0 +/- 210.0 ml, Group C: 404.7 +/- 243.2 ml p0.01), the first 24 hours drainage (Group A: 510.2 +/- 248.0 ml, Group C: 721 +/- 317.7 ml p0.01) was significantly reduced in Group A. Amounts of homologous blood transfusion were significantly reduced in group A. (Group A: 4.7 +/- 5.3 units, Group C: 8.5 +/- 6.4 units p0.01). Among the patients with autologous blood transfusion, the rate of the patients without homologous transfusion was significantly higher in Group A (group A: 40/66 cases, Group C: 8/33 cases p0.01). The ECC time and the operation time was significantly shorter in Group A. There were 69 patients (Group A: 40, Group C: 29) whose ECC time was longer than 120 minutes.(ABSTRACT TRUNCATED AT 250 WORDS)
- Published
- 1994
47. Electrically fused-egg induction and its development in the goldfish, Carassius auratus
- Author
-
E, Yamaha and F, Yamazaki
- Subjects
Cell Fusion ,Male ,Chimera ,Fertilization ,Goldfish ,Animals ,Female ,Membrane Fusion ,Vitelline Membrane ,Electric Stimulation ,Polyethylene Glycols - Abstract
In this study, we report the induction of cell fusion between two fertilized eggs and viable chimeric fish from the fused egg in goldfish. Chemical fusion by polyethylene glycol between denuded fertilized egg induced egg adhesion but rarely egg fusion. This treatment seemed not suitable for egg fusion, because of tight adhesion between vitelline membrane and surrounding matrix. Electrically fertilized egg fusion was successfully induced at the rate of almost 100% under conditions of 400V/cm, 1 MHz dielectrophoresis pulse for 3 seconds and a successive, 750V/cm, 10 microseconds fusion pulse. The treatment had to be applied to the egg in the calcium-free low electrolyte medium within 20 min of fertilization at 20 degrees C. Small numbers of fused eggs developed into young chimeric fish, and the different cells originating from two eggs survived together as an individual.
- Published
- 1993
48. Neovascularization effect with He-Ne laser in the rat trachea
- Author
-
F. Yamazaki, Hiromi Wada, Yutaka Takahashi, K. Cho, Toshiki Hirata, Shigeki Hitomi, and T. Fukuse
- Subjects
Pulmonary and Respiratory Medicine ,Male ,Pathology ,medicine.medical_specialty ,Rat Trachea ,Neon ,Helium ,Neovascularization ,Medicine ,He ne laser ,Animals ,Neovascularization, Pathologic ,business.industry ,Abdominal skin ,Lasers ,Significant difference ,Rats, Inbred F344 ,Staining ,Rats ,Transplantation ,Trachea ,Surgery ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business ,Wound healing - Abstract
The tracheal tissue of a rat was heterotopically transplanted beneath the abdominal skin of a syngenetic rat, and the transplanted graft was irradiated with a He-Ne laser (2.41 J/cm2). Four or seven days following transplantation, Chinese ink staining was used to ascertain the number of newly generated vessels. Rats sacrificed on day 4 were divided into 3 groups, according to the number of laser irradiation treatments: A0, A2, and A4. Similarly, rats sacrificed on day 7 were divided into groups B0, B2, and B4. Among the A groups, vascular counts were 49.5 +/- 31.1 in group A0 (n = 6), 108.9 +/- 34.7 in group A2 (n = 7), and 90.9 +/- 24.6 in group A4 (n = 4). Neovascularization was significantly more pronounced in the irradiated groups that in the non-irradiated group. In the B groups, vascular counts were 148 +/- 58 in group B0 (n = 6), 146 +/- 56 in group B2 (n = 5), and 147 +/- 49 in group B4 (n = 5). There was no significant difference between the irradiated and non-irradiated B groups. Laser irradiation was determined to stimulate neovascularization, and the possibility of a clinical application for this procedure was suggested.
- Published
- 1992
49. The role of dextran 40 and potassium in extended hypothermic lung preservation for transplantation
- Author
-
S H, Keshavjee, F, Yamazaki, H, Yokomise, P F, Cardoso, J B, Mullen, A S, Slutsky, and G A, Patterson
- Subjects
Solutions ,Pulmonary Circulation ,Dogs ,Hemodynamics ,Potassium ,Animals ,Bronchi ,Dextrans ,Organ Preservation ,Lung ,Lung Transplantation - Abstract
We have previously demonstrated that a low-potassium dextran solution provides superior and more reliable preservation of lungs for 12 hours than that provided by the commonly used Euro-Collins solution. This study was designed to examine the individual contributions of dextran 40 and a low (extracellular) potassium concentration to lung preservation. In a randomized, blinded study using an in vivo canine single-lung transplant model, lungs preserved with low-potassium dextran solution (K+, 4 mmol/L; dextran 40, 20 gm/L) were compared to lungs preserved with low-potassium, no-dextran solution (K+, 4 mmol/L) and high-potassium dextran solution (K+, 123 mmol/L; dextran 40, 20 gm/L). The lungs were assessed immediately and 3 days after transplantation. The low-potassium dextran solution provided excellent immediate pulmonary function with little variability (arterial oxygen tension, 519 +/- 12 mm Hg, measured on the transplanted lung alone, inspired oxygen fraction = 1.0, n = 6). Removing the dextran 40 from the flush solution (low-potassium group) led to a significant deterioration in pulmonary function (arterial oxygen tension, 243 +/- 78 mm Hg, n = 6, p less than 0.01). The high-potassium dextran solution provided extremely poor preservation (arterial oxygen tension, 176 +/- 79 mm Hg; n = 6; p less than 0.01). Two animals in this group died within 6 hours of operation. Viability of the transplanted bronchus was significantly improved with the two solutions containing dextran 40. These results indicate that dextran 40 and low potassium concentration both contribute significantly to the uniformly excellent 12-hour lung preservation seen with the low-potassium dextran solution.
- Published
- 1992
50. [From general hospital to hospice]
- Author
-
F, Yamazaki
- Subjects
Hospice Care ,Hospices ,Humans ,Hospitals, General - Published
- 1991
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.