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12 results on '"FAILLACI, FRANCESCA"'

2. AISF position paper on liver transplantation and pregnancy: Women in Hepatology Group, Italian Association for the Study of the Liver (AISF)

Author

Alisi, Anna, Balsano, Clara, Bernabucci, Veronica, Berzigotti, Annalisa, Brunetto, Maurizia, Bugianesi, Elisabetta, Burra, Patrizia, Calvaruso, Vincenza, Cariani, Elisabetta, Coco, Barbara, Colle, Isabelle, Critelli, Rosina, De Martin, Eleonora, Del Buono, Mariagrazia, Fabregat, Isabel, Faillaci, Francesca, Fattovich, Giovanna, Floreani, Annarosa, Garcia-Tsao, Guadalupe, Housset, Chantal, Karampatou, Aimilia, Lei, Barbara, Mangia, Alessandra, Martinez-Chantar, Maria Luz, Milosa, Fabiola, Morisco, Filomena, Nasta, Paola, Ozben, Tomris, Pollicino, Teresa, Ponti, Maria Laura, Pontisso, Patrizia, Reeves, Helen, Rendina, Maria, Rodríguez-Castro, Kryssia Isabel, Sagnelli, Caterina, Sebastiani, Giada, Smedile, Antonella, Taliani, Gloria, Vandelli, Carmen, Vanni, Ester, Villa, Erica, Vukotic, Ranka, Zignego, Anna Linda, Rodríguez-Castro, Kryssia, Guarino, Maria, and Mazzella, Giuseppe

Published
2016
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3. Liver Angiopoietin-2 is a key predictor of de novo or recurrent hepatocellular cancer after HCV direct-acting antivirals

Author

Faillaci, Francesca, Marzi, Luca, Critelli, Rosina, Milosa, Fabiola, Schepis, Filippo, Turola, Elena, Andreani, Silvia, Vandelli, Gabriele, Bernabucci, Veronica, Lei, Barbara, D'Ambrosio, Federica, Bristot, Laura, Cavalletto, Luisa, Chemello, Liliana, Sighinolfi, Pamela, Manni, Paola, Maiorana, Antonino, Caporali, Cristian, Bianchini, Marcello, Marsico, Maria, Turco, Laura, de Maria, Nicola, Del Buono, Mariagrazia, Todesca, Paola, di Lena, Luca, Romagnoli, Dante, Magistri, Paolo, di Benedetto, Fabrizio, Bruno, Savino, Taliani, Gloria, Giannelli, Gianluigi, Martinez-Chantar, Maria-Luz, and Villa, Erica

Subjects
Shear stress, Fibrosis, Liver stiffness, Portal hypertension, Vascular endothelial growth factor
Published
2018

4. Obese zebrafish: A small fish for a major human health condition

Author

Faillaci, Francesca, Milosa, Fabiola, Critelli, Rosina Maria, Turola, Elena, Schepis, Filippo, and Villa, Erica

Subjects
0301 basic medicine, obesity, Offspring, Review Article, Disease, Bioinformatics, metabolic diseases, 03 medical and health sciences, Human health, 0302 clinical medicine, NAFLD, Medicine, Metabolic disease, Zebrafish, biology, business.industry, Fatty liver, General Medicine, zebrafish, biology.organism_classification, medicine.disease, Obesity, 030104 developmental biology, inflammation, %22">Fish , business, 030217 neurology & neurosurgery
Abstract

Obesity is becoming a silent worldwide epidemic, with a steady increase in both adults and children. To date, even though several drugs have been licensed for long‐term obesity treatment, none of them are yet used in routine clinical practice. So far the only successful intervention has been behavioral therapy. A suitable and economic experimental model mimicking the human condition would therefore be extremely useful to evaluate preventive measures and novel treatments. Zebrafish are emerging as an important model system to study obesity and related metabolic disease. Remarkable similarities have been reported in lipid metabolism and the adipogenic pathway between zebrafish and mammals. Moreover, the zebrafish possesses a number of features—the relative inexpensiveness of animal husbandry, its optical transparency and the ability to produce a large number of offspring at low cost—that make it ideal for large‐scale screening and for testing drugs and intervention. In this review, we summarize recent progress in using zebrafish as a model system to study obesity and obesity‐related metabolic disorders. We describe several zebrafish models (in both larvae and adult animals) that develop obesity and non‐alcoholic fatty liver disease (NAFLD) using different approaches, including gene manipulation, diet manipulation and modification of microbiota composition. For these models, we have outlined the specific aspects related to obesity and its development and we have summarized their advantages and limitations.

Published
2018

6. Liver Angiopoietin‐2 Is a Key Predictor of D e N ovo or Recurrent Hepatocellular Cancer After Hepatitis C Virus Direct‐Acting Antivirals

Author

Faillaci, Francesca, primary, Marzi, Luca, additional, Critelli, Rosina, additional, Milosa, Fabiola, additional, Schepis, Filippo, additional, Turola, Elena, additional, Andreani, Silvia, additional, Vandelli, Gabriele, additional, Bernabucci, Veronica, additional, Lei, Barbara, additional, D'Ambrosio, Federica, additional, Bristot, Laura, additional, Cavalletto, Luisa, additional, Chemello, Liliana, additional, Sighinolfi, Pamela, additional, Manni, Paola, additional, Maiorana, Antonino, additional, Caporali, Cristian, additional, Bianchini, Marcello, additional, Marsico, Maria, additional, Turco, Laura, additional, de Maria, Nicola, additional, Del Buono, Mariagrazia, additional, Todesca, Paola, additional, di Lena, Luca, additional, Romagnoli, Dante, additional, Magistri, Paolo, additional, di Benedetto, Fabrizio, additional, Bruno, Savino, additional, Taliani, Gloria, additional, Giannelli, Gianluigi, additional, Martinez‐Chantar, Maria‐Luz, additional, and Villa, Erica, additional

Published
2018
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8. Microenvironment inflammatory infiltrate drives growth speed and outcome of hepatocellular carcinoma: a prospective clinical study

Author

Critelli, Rosina, primary, Milosa, Fabiola, additional, Faillaci, Francesca, additional, Condello, Rosario, additional, Turola, Elena, additional, Marzi, Luca, additional, Lei, Barbara, additional, Dituri, Francesco, additional, Andreani, Silvia, additional, Sighinolfi, Pamela, additional, Manni, Paola, additional, Maiorana, Antonino, additional, Caporali, Cristian, additional, di Benedetto, Fabrizio, additional, Del Buono, Mariagrazia, additional, De Maria, Nicola, additional, Schepis, Filippo, additional, Martinez-Chantar, Maria-Luz, additional, Giannelli, Gianluigi, additional, and Villa, Erica, additional

Published
2017
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9. Liver Angiopoietin‐2 Is a Key Predictor of De Novo or Recurrent Hepatocellular Cancer After Hepatitis C Virus Direct‐Acting Antivirals.

Author

Faillaci, Francesca, Marzi, Luca, Critelli, Rosina, Milosa, Fabiola, Schepis, Filippo, Turola, Elena, Andreani, Silvia, Vandelli, Gabriele, Bernabucci, Veronica, Lei, Barbara, D'Ambrosio, Federica, Bristot, Laura, Cavalletto, Luisa, Chemello, Liliana, Sighinolfi, Pamela, Manni, Paola, Maiorana, Antonino, Caporali, Cristian, Bianchini, Marcello, and Marsico, Maria

Published
2018
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10. EPIGENESIS AS KEY CONCEPT FOR UNDERSTANDING FUNCTIONAL AND DYSFUNCTIONAL REACTIONS OF HUMAN BEINGS TO THEIR ENVIRONMENT.

Author

GIUFFRIDA, PIETRO, FAILLACI, FRANCESCA, and SIDELI, LUCIA

Subjects
*GENETICS, *EPIGENESIS, *GREEK & Roman medicine, *DNA, *ANCIENT medicine, *HISTORY of medicine
Abstract

Epigenetics is regarded as a promising research field to better understand the interplay between genetic and environmental factors underlying both typical and atypical developmental processes (from embryonic cell specialization to severe neurological and mental disorders). The aim of this paper is to describe the history of the concept of epigenesis from its Aristotelian foundation. Emphasizing the relation between internal powers and external factors of change, Aristotle seems to anticipate the current meaning of epigenetics, coined by Conrad Waddington in 1940 and then developed by the modern genetics. The discovery of epigeneic mechanisms has challenged the static nature of DNA pointing out the dynamic and reversible changes occurring in response to environmental prompts. This stimulates considerations on the relational nature of life in the response to various environmental stimuli. [ABSTRACT FROM AUTHOR]

Published
2017

11. EPIGENESIS AS KEY CONCEPT FOR UNDERSTANDING FUNCTIONAL AND DYSFUNCTIONAL REACTIONS OF HUMAN BEINGS TO THEIR ENVIRONMENT.

Author

GIUFFRIDA, PIETRO, FAILLACI, FRANCESCA, and SIDELI, LUCIA

Subjects
*EPIGENETICS, *SCHIZOPHRENIA, *GENETICS -- History, *HISTORY
Abstract

Epigenetics is regarded as a promising research field to better understand the interplay between genetic and environmental factors underlying both typical and atypical developmental processes (from embryonic cell specialization to severe neurological and mental disorders). The aim of this paper is to describe the history of the concept of epigenesis from its Aristotelian foundation. Emphasizing the relation between internal powers and external factors of change, Aristotle seems to anticipate the current meaning of epigenetics, coined by Conrad Waddington in 1940 and then developed by the modern genetics. The discovery of epigenetic mechanisms has challenged the static nature of DNA pointing out the dynamic and reversible changes occurring in response to environmental prompts. This stimulates considerations on the relational nature of life in the response to various environmental stimuli. [ABSTRACT FROM AUTHOR]

Published
2016

12. AISF position paper on liver transplantation and pregnancy: Women in Hepatology Group, Italian Association for the Study of the Liver (AISF)

Author

Burra, P, Rodríguez-Castro, K, Guarino, M, Morisco, F, Villa, E, Mazzella, G, Women in Hepatology Group, Italian Association for the Study of the Liver (AISF) (Alisi, A, Balsano, C, Bernabucci, V, Berzigotti, A, Brunetto, M, Bugianesi, E, Calvaruso, V, Cariani, E, Coco, B, Colle, I, Critelli, R, De Martin, E, Del Buono, M, Fabregat, I, Faillaci, F, Fattovich, G, Floreani, A, Garcia-Tsao, G, Housset, C, Karampatou, A, Lei, B, Mangia, A, Martinez-Chantar, Ml, Milosa, F, Nasta, P, Ozben, T, Pollicino, T, Ponti, Ml, Pontisso, P, Reeves, H, Rendina, M, Rodríguez-Castro, Ki, Sagnelli, C, Sebastiani, Giulia, Smedile, A, Taliani, G, Vandelli, C, Vanni, E, Vukotic, R, Zignego, Al), Alisi A, Balsano C, Bernabucci V, Berzigotti A, Brunetto M, Bugianesi E, Burra P, Calvaruso V, Cariani E, Coco B, Colle I, Critelli R, De Martin E, Del Buono M, Fabregat I, Faillaci F, Fattovich G, Floreani A, Garcia-Tsao G, Housset C, Karampatou A, Lei B, Mangia A, Martinez-Chantar ML, Milosa F, Morisco F, Nasta P, Ozben T, Pollicino T, Ponti ML, Pontisso P, Reeves H, Rendina M, Rodríguez-Castro KI, Sagnelli C, Sebastiani G, Smedile A, Taliani G, Vandelli C, Vanni E, Villa E, Vukotic R, Zignego AL, Burra P, Rodríguez-Castro K, Guarino M, Morisco F, Villa E, Mazzella G., Alisi, A, Balsano, C, Bernabucci, V, Berzigotti, A, Brunetto, M, Bugianesi, E, Burra, P, Calvaruso, V, Cariani, E, Coco, B, Colle, I, Critelli, R, De Martin, E, Del Buono, M, Fabregat, I, Faillaci, F, Fattovich, G, Floreani, A, Garcia-Tsao, G, Housset, C, Karampatou, A, Lei, B, Mangia, A, Martinez-Chantar, Ml, Milosa, F, Morisco, F, Nasta, P, Ozben, T, Pollicino, T, Ponti, Ml, Pontisso, P, Reeves, H, Rendina, M, Rodríguez-Castro, Ki, Sagnelli, C, Sebastiani, G, Smedile, A, Taliani, G, Vandelli, C, Vanni, E, Vukotic, R, Zignego, Al, Rodríguez-Castro, K, Guarino, M, Villa, E, Mazzella, G., Garcia Tsao, G, Martinez Chantar, Ml, Morisco, Filomena, Rodríguez Castro, Ki, Rodríguez Castro, K, Guarino, Maria, Alisi, Anna, Balsano, Clara, Bernabucci, Veronica, Berzigotti, Annalisa, Brunetto, Maurizia, Bugianesi, Elisabetta, Burra, Patrizia, Calvaruso, Vincenza, Cariani, Elisabetta, Coco, Barbara, Colle, Isabelle, Critelli, Rosina, De Martin, Eleonora, Del Buono, Mariagrazia, Fabregat, Isabel, Faillaci, Francesca, Fattovich, Giovanna, Floreani, Annarosa, Garcia-tsao, Guadalupe, Housset, Chantal, Karampatou, Aimilia, Lei, Barbara, Mangia, Alessandra, Martinez-chantar, Maria Luz, Milosa, Fabiola, Nasta, Paola, Ozben, Tomri, Pollicino, Teresa, Ponti, Maria Laura, Pontisso, Patrizia, Reeves, Helen, Rendina, Maria, Rodrã­guez-castro, Kryssia Isabel, Sagnelli, Caterina, Sebastiani, Giada, Smedile, Antonella, Taliani, Gloria, Vandelli, Carmen, Vanni, Ester, Villa, Erica, Vukotic, Ranka, Zignego, Anna Linda, Rodrã­guez-castro, Kryssia, and Mazzella, Giuseppe

Subjects
Risk Assessment, Fertility, Immunosuppression, Liver transplantation, Pregnancy, Immunosuppressive Agent, Medical, Hepatology, Gastroenterology, Humans, Obstetric Labor Complication, Societies, Medical, Postpartum Period, Pregnancy Outcome, Contraception, Female, Italy, Obstetric Labor Complications, Practice Guidelines as Topic, Pregnancy Complications, Immunosuppressive Agents, Liver Transplantation, Pregnancy Complication, surgical procedures, operative, Societies, Human
Abstract

After the first successful pregnancy in a liver transplant recipient in 1978, much evidence has accumulated on the course, outcomes and management strategies of pregnancy following liver transplantation. Generally, liver transplantation restores sexual function and fertility as early as a few months after transplant. Considering that one third of all liver transplant recipients are women, that approximately one-third of them are of reproductive age (18-49 years), and that 15% of female liver transplant recipients are paediatric patients who have a >70% probability of reaching reproductive age, the issue of pregnancy after liver transplantation is rather relevant, and obstetricians, paediatricians, and transplant hepatologists ever more frequently encounter such patients. Pregnancy outcomes for both the mother and infant in liver transplant recipients are generally good, but there is an increased incidence of preterm delivery, hypertension/preeclampsia, foetal growth restriction, and gestational diabetes, which, by definition, render pregnancy in liver transplant recipients a high-risk one. In contrast, the risk of congenital anomalies and the live birth rate are comparable to those of the general population. Currently there are still no robust guidelines on the management of pregnancies after liver transplantation. The aim of this position paper is to review the available evidence on pregnancy in liver transplant recipients and to provide national Italian recommendations for clinicians caring for these patients. (C) 2016 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

Published
2016

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