20 results on '"FERRANTE, Luisa"'
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2. Nature of Neurological Complications and Outcome After Surgery for Type A Aortic Dissection
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Biancari, Fausto, Onorati, Francesco, Peterss, Sven, Buech, Joscha, Mariscalco, Giovanni, Lega, Javier Rodriguez, Pinto, Angel G., Fiore, Antonio, Perrotti, Andrea, Hérve, Amelié, Rukosujew, Andreas, Demal, Till, Conradi, Lenard, Wisniewski, Konrad, Pol, Marek, Kacer, Petr, Gatti, Giuseppe, Mazzaro, Enzo, Vendramin, Igor, Piani, Daniela, Rinaldi, Mauro, Ferrante, Luisa, Pruna-Guillen, Robert, Di Perna, Dario, Gerelli, Sebastien, El-Dean, Zein, Nappi, Francesco, Field, Mark, Kuduvalli, Manoj, Pettinari, Matteo, Francica, Alessandra, Jormalainen, Mikko, Dell'Aquila, Angelo M., Mäkikallio, Timo, Juvonen, Tatu, and Quintana, Eduard
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- 2024
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3. Classification of the Urgency of the Procedure and Outcome of Acute Type A Aortic Dissection
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Biancari, Fausto, Dell'Aquila, Angelo M., Onorati, Francesco, Rossetti, Cecilia, Demal, Till, Rukosujew, Andreas, Peterss, Sven, Buech, Joscha, Fiore, Antonio, Folliguet, Thierry, Perrotti, Andrea, Hervé, Amélie, Nappi, Francesco, Conradi, Lenard, Pinto, Angel G., Lega, Javier Rodriguez, Pol, Marek, Kacer, Petr, Wisniewski, Konrad, Mazzaro, Enzo, Gatti, Giuseppe, Vendramin, Igor, Piani, Daniela, Ferrante, Luisa, Rinaldi, Mauro, Quintana, Eduard, Pruna-Guillen, Robert, Gerelli, Sebastien, Di Perna, Dario, Acharya, Metesh, Mariscalco, Giovanni, Field, Mark, Kuduvalli, Manoj, Pettinari, Matteo, Rosato, Stefano, Mustonen, Caius, Kiviniemi, Tuomas, Roberts, Charles S., Mäkikallio, Timo, and Juvonen, Tatu
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- 2024
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4. Interinstitutional analysis of the outcome after surgery for type A aortic dissection
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Biancari, Fausto, Dell’Aquila, Angelo M., Gatti, Giuseppe, Perrotti, Andrea, Hervé, Amélie, Touma, Joseph, Pettinari, Matteo, Peterss, Sven, Buech, Joscha, Wisniewski, Konrad, Juvonen, Tatu, Jormalainen, Mikko, Mustonen, Caius, Rukosujew, Andreas, Demal, Till, Conradi, Lenard, Pol, Marek, Kacer, Petr, Onorati, Francesco, Rossetti, Cecilia, Vendramin, Igor, Piani, Daniela, Rinaldi, Mauro, Ferrante, Luisa, Quintana, Eduard, Pruna-Guillen, Robert, Lega, Javier Rodriguez, Pinto, Angel G., Acharya, Metesh, El-Dean, Zein, Field, Mark, Harky, Amer, Kuduvalli, Manoj, Nappi, Francesco, Gerelli, Sebastien, Di Perna, Dario, Mazzaro, Enzo, Rosato, Stefano, Fiore, Antonio, and Mariscalco, Giovanni
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- 2023
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5. Malperfusion syndrome in patients undergoing repair for acute type A aortic dissection: Presentation, mortality, and utility of the Penn classification
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Dell’Aquila, Angelo M., Wisniewski, Konrad, Georgevici, Adrian-Iustin, Szabó, Gábor, Onorati, Francesco, Rossetti, Cecilia, Conradi, Lenard, Demal, Till, Rukosujew, Andreas, Peterss, Sven, Caroline, Radner, Buech, Joscha, Fiore, Antonio, Folliguet, Thierry, Perrotti, Andrea, Hervé, Amélie, Nappi, Francesco, Pinto, Angel G., Lega, Javier Rodriguez, Pol, Marek, Kacer, Petr, Mazzaro, Enzo, Gatti, Giuseppe, Vendramin, Igor, Piani, Daniela, Ferrante, Luisa, Rinaldi, Mauro, Quintana, Eduard, Pruna-Guillen, Robert, Gerelli, Sebastien, Di Perna, Dario, Acharya, Metesh, Sherzad, Hiwa, Mariscalco, Giovanni, Field, Mark, Harky, Amer, Kuduvalli, Manoj, Pettinari, Matteo, Rosato, Stefano, Juvonen, Tatu, Mikko, Jormalainen, Mäkikallio, Timo, Mustonen, Caius, and Biancari, Fausto
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- 2024
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6. Preoperative arterial lactate and outcome after surgery for type A aortic dissection: The ERTAAD multicenter study
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Biancari, Fausto, Nappi, Francesco, Gatti, Giuseppe, Perrotti, Andrea, Hervé, Amélie, Rosato, Stefano, D'Errigo, Paola, Pettinari, Matteo, Peterss, Sven, Buech, Joscha, Juvonen, Tatu, Jormalainen, Mikko, Mustonen, Caius, Demal, Till, Conradi, Lenard, Pol, Marek, Kacer, Petr, Dell’Aquila, Angelo M., Wisniewski, Konrad, Vendramin, Igor, Piani, Daniela, Ferrante, Luisa, Mäkikallio, Timo, Quintana, Eduard, Pruna-Guillen, Robert, Fiore, Antonio, Folliguet, Thierry, Mariscalco, Giovanni, Acharya, Metesh, Field, Mark, Kuduvalli, Manoj, Onorati, Francesco, Rossetti, Cecilia, Gerelli, Sebastien, Di Perna, Dario, Mazzaro, Enzo, Pinto, Angel G., Lega, Javier Rodriguez, and Rinaldi, Mauro
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- 2023
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7. Current Outcome after Surgery for Type A Aortic Dissection
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Biancari, Fausto, Juvonen, Tatu, Fiore, Antonio, Perrotti, Andrea, Hervé, Amélie, Touma, Joseph, Pettinari, Matteo, Peterss, Sven, Buech, Joscha, Dell’Aquila, Angelo M., Wisniewski, Konrad, Rukosujew, Andreas, Demal, Till, Conradi, Lenard, Pol, Marek, Kacer, Petr, Onorati, Francesco, Rossetti, Cecilia, Vendramin, Igor, Piani, Daniela, Rinaldi, Mauro, Ferrante, Luisa, Quintana, Eduard, Pruna-Guillen, Robert, Rodriguez Lega, Javier, Pinto, Angel G., Acharya, Metesh, El-Dean, Zein, Field, Mark, Harky, Amer, Nappi, Francesco, Gerelli, Sebastien, Di Perna, Dario, Gatti, Giuseppe, Mazzaro, Enzo, Rosato, Stefano, Raivio, Peter, Jormalainen, Mikko, and Mariscalco, Giovanni
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- 2023
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8. The David Versus the Bentall Procedure for Acute Type A Aortic Dissection.
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Biancari, Fausto, Mastroiacovo, Giorgio, Rinaldi, Mauro, Ferrante, Luisa, Mäkikallio, Timo, Juvonen, Tatu, Mariscalco, Giovanni, El-Dean, Zein, Pettinari, Matteo, Rodriguez Lega, Javier, Pinto, Angel G., Perrotti, Andrea, Onorati, Francesco, Wisniewski, Konrad, Demal, Till, Kacer, Petr, Rocek, Jan, Di Perna, Dario, Vendramin, Igor, and Piani, Daniela
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- 2024
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9. Baseline risk factors of in-hospital mortality after surgery for acute type A aortic dissection: an ERTAAD study
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Biancari, Fausto, primary, Demal, Till, additional, Nappi, Francesco, additional, Onorati, Francesco, additional, Francica, Alessandra, additional, Peterss, Sven, additional, Buech, Joscha, additional, Fiore, Antonio, additional, Folliguet, Thierry, additional, Perrotti, Andrea, additional, Hervé, Amélie, additional, Conradi, Lenard, additional, Rukosujew, Andreas, additional, Pinto, Angel G., additional, Lega, Javier Rodriguez, additional, Pol, Marek, additional, Rocek, Jan, additional, Kacer, Petr, additional, Wisniewski, Konrad, additional, Mazzaro, Enzo, additional, Vendramin, Igor, additional, Piani, Daniela, additional, Ferrante, Luisa, additional, Rinaldi, Mauro, additional, Quintana, Eduard, additional, Pruna-Guillen, Robert, additional, Gerelli, Sebastien, additional, Di Perna, Dario, additional, Acharya, Metesh, additional, Mariscalco, Giovanni, additional, Field, Mark, additional, Kuduvalli, Manoj, additional, Pettinari, Matteo, additional, Rosato, Stefano, additional, D’Errigo, Paola, additional, Jormalainen, Mikko, additional, Mustonen, Caius, additional, Mäkikallio, Timo, additional, Dell’Aquila, Angelo M., additional, Juvonen, Tatu, additional, and Gatti, Giuseppe, additional
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- 2024
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10. Correction to: European registry of type A aortic dissection (ERTAAD) - rationale, design and definition criteria
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Biancari, Fausto, Mariscalco, Giovanni, Yusuff, Hakeem, Tsang, Geoffrey, Luthra, Suvitesh, Onorati, Francesco, Francica, Alessandra, Rossetti, Cecilia, Perrotti, Andrea, Chocron, Sidney, Fiore, Antonio, Folliguet, Thierry, Pettinari, Matteo, Dell’Aquila, Angelo M., Demal, Till, Conradi, Lenard, Detter, Christian, Pol, Marek, Ivak, Peter, Schlosser, Filip, Forlani, Stefano, Chetty, Govind, Harky, Amer, Kuduvalli, Manoj, Field, Mark, Vendramin, Igor, Livi, Ugolino, Rinaldi, Mauro, Ferrante, Luisa, Etz, Christian, Noack, Thilo, Mastrobuoni, Stefano, De Kerchove, Laurent, Jormalainen, Mikko, Laga, Steven, Meuris, Bart, Schepens, Marc, Dean, Zein El, Vento, Antti, Raivio, Peter, Borger, Michael, and Juvonen, Tatu
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- 2021
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11. European registry of type A aortic dissection (ERTAAD) - rationale, design and definition criteria
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Biancari, Fausto, Mariscalco, Giovanni, Yusuff, Hakeem, Tsang, Geoffrey, Luthra, Suvitesh, Onorati, Francesco, Francica, Alessandra, Rossetti, Cecilia, Perrotti, Andrea, Chocron, Sidney, Fiore, Antonio, Folliguet, Thierry, Pettinari, Matteo, Dell’Aquila, Angelo M., Demal, Till, Conradi, Lenard, Detter, Christian, Pol, Marek, Ivak, Peter, Schlosser, Filip, Forlani, Stefano, Chetty, Govind, Harky, Amer, Kuduvalli, Manoj, Field, Mark, Vendramin, Igor, Livi, Ugolino, Rinaldi, Mauro, Ferrante, Luisa, Etz, Christian, Noack, Thilo, Mastrobuoni, Stefano, De Kerchove, Laurent, Jormalainen, Mikko, Laga, Steven, Meuris, Bart, Schepens, Marc, El Dean, Zein, Vento, Antti, Raivio, Peter, Borger, Michael, and Juvonen, Tatu
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- 2021
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12. Homograft Aortic Root Replacement for Destructive Prosthetic Valve Endocarditis: Results in the Current Era.
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Pocar, Marco, Barbero, Cristina, Marro, Matteo, Ferrante, Luisa, Costamagna, Andrea, Fazio, Luigina, La Torre, Michele, Boffini, Massimo, Salizzoni, Stefano, and Rinaldi, Mauro
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PROSTHETIC heart valves ,INFECTIVE endocarditis ,ASPARTATE aminotransferase ,CARDIAC output ,AORTA - Abstract
Background: Destructive aortic prosthetic valve endocarditis portends a high morbidity and mortality, and requires complex high-risk surgery. Homograft root replacement is the most radical and biocompatible operation and, thus, the preferred option. Methods: A retrospective analysis was conducted on 61 consecutive patients who underwent a cardiac reoperation comprising homograft aortic root replacement since 2010. The probabilities of survival were calculated with the Kaplan–Meier method, whereas multivariable regression served to outline the predictors of adverse events. The endpoints were operative/late death, perioperative low cardiac output and renal failure, and reoperations. Results: The operative (cumulative hospital and 30-day) mortality was 13%. The baseline aspartate transaminase (AST) and associated mitral procedures were predictive of operative death (p = 0.048, OR [95% CIs] = 1.03 [1–1.06]) and perioperative low cardiac output, respectively (p = 0.04, OR [95% CIs] = 21.3 [2.7–168.9] for valve replacement). The latter occurred in 12 (20%) patients, despite a normal ejection fraction. Survival estimates (±SE) at 3 months, 6 months, 1 year, and 3 years after surgery were 86.3 ± 4.7%, 82.0 ± 4.9%, 75.2 ± 5.6, and 70.0 ± 6.3%, respectively. Survival was significantly lower in the case of AST ≥ 40 IU/L (p = 0.04) and aortic cross-clamp time ≥ 180 min (p = 0.01), but not when excluding operative survivors. Five patients required early (two out of the five, within 3 months) or late (three out of the five) reoperation. Conclusions: Homograft aortic root replacement for destructive prosthetic valve endocarditis can currently be performed with a near 90% operative survival and reasonable 3-year mortality and reoperation rate. AST might serve to additionally stratify the operative risk. [ABSTRACT FROM AUTHOR]
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- 2024
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13. Predictors, prognosis and costs of prolonged intensive care unit stay after surgery for type A aortic dissection.
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BIANCARI, Fausto, HÉRVE, Amelié, PETERSS, Sven, RADNER, Caroline, BUECH, Joscha, PETTINARI, Matteo, LEGA, Javier RODRIGUEZ, PINTO, Angel G., FIORE, Antonio, ONORATI, Francesco, FRANCICA, Alessandra, WISNIEWSKI, Konrad, DEMAL, Till, CONRADI, Lenard, ROCEK, Jan, KACER, Petr, GATTI, Giuseppe, VENDRAMIN, Igor, RINALDI, Mauro, and FERRANTE, Luisa
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- 2024
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14. Outcome after Surgery for Iatrogenic Acute Type A Aortic Dissection
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Biancari, Fausto, primary, Pettinari, Matteo, additional, Mariscalco, Giovanni, additional, Mustonen, Caius, additional, Nappi, Francesco, additional, Buech, Joscha, additional, Hagl, Christian, additional, Fiore, Antonio, additional, Touma, Joseph, additional, Dell’Aquila, Angelo M., additional, Wisniewski, Konrad, additional, Rukosujew, Andreas, additional, Perrotti, Andrea, additional, Hervé, Amélie, additional, Demal, Till, additional, Conradi, Lenard, additional, Pol, Marek, additional, Kacer, Petr, additional, Onorati, Francesco, additional, Rossetti, Cecilia, additional, Vendramin, Igor, additional, Piani, Daniela, additional, Rinaldi, Mauro, additional, Ferrante, Luisa, additional, Quintana, Eduard, additional, Pruna-Guillen, Robert, additional, Rodriguez Lega, Javier, additional, Pinto, Angel G., additional, Mäkikallio, Timo, additional, Acharya, Metesh, additional, El-Dean, Zein, additional, Field, Mark, additional, Harky, Amer, additional, Gerelli, Sebastien, additional, Di Perna, Dario, additional, Jormalainen, Mikko, additional, Gatti, Giuseppe, additional, Mazzaro, Enzo, additional, Juvonen, Tatu, additional, and Peterss, Sven, additional
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- 2022
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15. European registry of type A aortic dissection (ERTAAD) - rationale, design and definition criteria.
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UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - (SLuc) Service de chirurgie cardiovasculaire et thoracique, Biancari, Fausto, Mariscalco, Giovanni, Yusuff, Hakeem, Tsang, Geoffrey, Luthra, Suvitesh, Onorati, Francesco, Francica, Alessandra, Rossetti, Cecilia, Perrotti, Andrea, Chocron, Sidney, Fiore, Antonio, Folliguet, Thierry, Pettinari, Matteo, Dell'Aquila, Angelo M, Demal, Till, Conradi, Lenard, Detter, Christian, Pol, Marek, Ivak, Peter, Schlosser, Filip, Forlani, Stefano, Chetty, Govind, Harky, Amer, Kuduvalli, Manoj, Field, Mark, Vendramin, Igor, Livi, Ugolino, Rinaldi, Mauro, Ferrante, Luisa, Etz, Christian, Noack, Thilo, Mastrobuoni, Stefano, de Kerchove, Laurent, Jormalainen, Mikko, Laga, Steven, Meuris, Bart, Schepens, Marc, El Dean, Zein, Vento, Antti, Raivio, Peter, Borger, Michael, Juvonen, Tatu, UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - (SLuc) Service de chirurgie cardiovasculaire et thoracique, Biancari, Fausto, Mariscalco, Giovanni, Yusuff, Hakeem, Tsang, Geoffrey, Luthra, Suvitesh, Onorati, Francesco, Francica, Alessandra, Rossetti, Cecilia, Perrotti, Andrea, Chocron, Sidney, Fiore, Antonio, Folliguet, Thierry, Pettinari, Matteo, Dell'Aquila, Angelo M, Demal, Till, Conradi, Lenard, Detter, Christian, Pol, Marek, Ivak, Peter, Schlosser, Filip, Forlani, Stefano, Chetty, Govind, Harky, Amer, Kuduvalli, Manoj, Field, Mark, Vendramin, Igor, Livi, Ugolino, Rinaldi, Mauro, Ferrante, Luisa, Etz, Christian, Noack, Thilo, Mastrobuoni, Stefano, de Kerchove, Laurent, Jormalainen, Mikko, Laga, Steven, Meuris, Bart, Schepens, Marc, El Dean, Zein, Vento, Antti, Raivio, Peter, Borger, Michael, and Juvonen, Tatu
- Abstract
BACKGROUND: Acute Stanford type A aortic dissection (TAAD) is a life-threatening condition. Surgery is usually performed as a salvage procedure and is associated with significant postoperative early mortality and morbidity. Understanding the patient's conditions and treatment strategies which are associated with these adverse events is essential for an appropriate management of acute TAAD. METHODS: Nineteen centers of cardiac surgery from seven European countries have collaborated to create a multicentre observational registry (ERTAAD), which will enroll consecutive patients who underwent surgery for acute TAAD from January 2005 to March 2021. Analysis of the impact of patient's comorbidities, conditions at referral, surgical strategies and perioperative treatment on the early and late adverse events will be performed. The investigators have developed a classification of the urgency of the procedure based on the severity of preoperative hemodynamic conditions and malperfusion secondary to acute TAAD. The primary clinical outcomes will be in-hospital mortality, late mortality and reoperations on the aorta. Secondary outcomes will be stroke, acute kidney injury, surgical site infection, reoperation for bleeding, blood transfusion and length of stay in the intensive care unit. DISCUSSION: The analysis of this multicentre registry will allow conclusive results on the prognostic importance of critical preoperative conditions and the value of different treatment strategies to reduce the risk of early adverse events after surgery for acute TAAD. This registry is expected to provide insights into the long-term durability of different strategies of surgical repair for TAAD. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT04831073 .
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- 2021
16. Correction to: European registry of type A aortic dissection (ERTAAD) - rationale, design and definition criteria.
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UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - (SLuc) Service de chirurgie cardiovasculaire et thoracique, Biancari, Fausto, Mariscalco, Giovanni, Yusuff, Hakeem, Tsang, Geoffrey, Luthra, Suvitesh, Onorati, Francesco, Francica, Alessandra, Rossetti, Cecilia, Perrotti, Andrea, Chocron, Sidney, Fiore, Antonio, Folliguet, Thierry, Pettinari, Matteo, Dell'Aquila, Angelo M, Demal, Till, Conradi, Lenard, Detter, Christian, Pol, Marek, Ivak, Peter, Schlosser, Filip, Forlani, Stefano, Chetty, Govind, Harky, Amer, Kuduvalli, Manoj, Field, Mark, Vendramin, Igor, Livi, Ugolino, Rinaldi, Mauro, Ferrante, Luisa, Etz, Christian, Noack, Thilo, Mastrobuoni, Stefano, de Kerchove, Laurent, Jormalainen, Mikko, Laga, Steven, Meuris, Bart, Schepens, Marc, Dean, Zein El, Vento, Antti, Raivio, Peter, Borger, Michael, Juvonen, Tatu, UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - (SLuc) Service de chirurgie cardiovasculaire et thoracique, Biancari, Fausto, Mariscalco, Giovanni, Yusuff, Hakeem, Tsang, Geoffrey, Luthra, Suvitesh, Onorati, Francesco, Francica, Alessandra, Rossetti, Cecilia, Perrotti, Andrea, Chocron, Sidney, Fiore, Antonio, Folliguet, Thierry, Pettinari, Matteo, Dell'Aquila, Angelo M, Demal, Till, Conradi, Lenard, Detter, Christian, Pol, Marek, Ivak, Peter, Schlosser, Filip, Forlani, Stefano, Chetty, Govind, Harky, Amer, Kuduvalli, Manoj, Field, Mark, Vendramin, Igor, Livi, Ugolino, Rinaldi, Mauro, Ferrante, Luisa, Etz, Christian, Noack, Thilo, Mastrobuoni, Stefano, de Kerchove, Laurent, Jormalainen, Mikko, Laga, Steven, Meuris, Bart, Schepens, Marc, Dean, Zein El, Vento, Antti, Raivio, Peter, Borger, Michael, and Juvonen, Tatu
- Abstract
Correction to:Journal of Cardiothoracic Surgery (2021) 16:171 - https://doi.org/10.1186/s13019-021-01536-5
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- 2021
17. Bridging aortic valve surgery to 21st century: what can a surgeon do?
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D��Abramo, Mizar, primary, Ferrante, Luisa, additional, Guerrera, Manuel, additional, Saade, Wael, additional, Greco, Ernesto, additional, Miraldi, Fabio, additional, Marullo, Antonino, additional, Peruzzi, Mariangela, additional, Barretta, Antonio, additional, Proietti, Piero, additional, Biondi-Zoccai, Giuseppe, additional, Sciarretta, Sebastiano, additional, Frati, Giacomo, additional, and Iaccarino, Alessandra, additional
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- 2019
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18. Ascending aortic replacement versus aortic root replacement in patients with type A aortic dissection involving the aortic root.
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Biancari F, Gatti G, Mäkikallio T, Juvonen T, Mariscalco G, El-Dean Z, Pettinari M, Rodriguez Lega J, Perrotti A, Onorati F, Wisniewki K, Demal T, Kacer P, Perna DD, Vendramin I, Rinaldi M, Ferrante L, Quintana E, Buech J, Radner C, Fiore A, Dell'Aquila AM, D'Errigo P, Rosato S, Polvani G, and Peterss S
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- Humans, Male, Female, Retrospective Studies, Middle Aged, Risk Factors, Aged, Treatment Outcome, Time Factors, Reoperation, Risk Assessment, Adult, Aortic Dissection surgery, Aortic Dissection mortality, Hospital Mortality, Blood Vessel Prosthesis Implantation adverse effects, Blood Vessel Prosthesis Implantation mortality, Postoperative Complications epidemiology, Postoperative Complications etiology, Postoperative Complications mortality, Aortic Aneurysm, Thoracic surgery, Aortic Aneurysm, Thoracic mortality, Aortic Aneurysm, Thoracic diagnostic imaging
- Abstract
Background: Extensive surgical resection of the thoracic aorta in patients with type A aortic dissection (TAAD) is thought to reduce the risk of late aortic wall degeneration and the need for repeat aortic operations., Objectives: We evaluated the early and late outcomes after aortic root replacement and supracoronary ascending aortic replacement in patients with TAAD involving the aortic root., Design: Retrospective, multicenter cohort study., Methods: The outcomes after aortic root replacement and supracoronary ascending aortic replacement in patients with TAAD involving the aortic root, that is dissection flap located at least in one of the Valsava segments, were herein evaluated. In-hospital mortality, neurological complications, dialysis as well as 10-year repeat proximal aortic operation, and mortality were the outcomes of this study., Results: Supracoronary ascending aortic replacement was performed in 198 patients and aortic root replacement in 215 patients. During a mean follow-up of 4.0 ± 4.0 years, 19 patients underwent 22 repeat procedures on the aortic root and/or aortic valve. No operative death occurred after these reinterventions. The risk of proximal aortic reoperation was significantly lower in patients who underwent aortic root replacement (5.5% vs 12.9%, adjusted subdistributional hazard ratio (SHR) 0.085, 95% CI 0.022-0.329). Aortic root replacement was associated with higher rates of in-hospital (14.4% vs 12.1%, adjusted odds ratio 2.192, 95% CI 1.000-4.807) and 10-year mortality (44.5% vs 30.4%, adjusted hazard ratio 2.216, 95% CI 1.338-3.671). Postoperative neurological complications and dialysis rates were comparable in the study groups., Conclusion: Among patients with TAAD involving the aortic root, its replacement was associated with a significantly lower rate of repeat proximal aortic operation of any type compared to supracoronary aortic replacement. Still, aortic root replacement seems to be associated with an increased risk of mortality in these patients., ClinicalTrials.gov: NCT04831073 (https://clinicaltrials.gov/study/NCT04831073).
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- 2025
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19. Role of gender in short- and long-term outcomes after surgery for type A aortic dissection: analysis of a multicentre European registry.
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Onorati F, Francica A, Demal T, Nappi F, Peterss S, Buech J, Fiore A, Folliguet T, Perrotti A, Hervé A, Conradi L, Dell'Aquila AM, Rukosujew A, Pinto AG, Lega JR, Pol M, Rocek J, Kacer P, Wisniewski K, Mazzaro E, Vendramin I, Piani D, Ferrante L, Rinaldi M, Quintana E, Pruna-Guillen R, Gerelli S, Acharya M, Mariscalco G, Field M, Kuduvalli M, Pettinari M, Rosato S, D'Errigo P, Jormalainen M, Mustonen C, Mäkikallio T, Di Perna D, Juvonen T, Gatti G, Luciani GB, and Biancari F
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- Humans, Male, Female, Retrospective Studies, Europe epidemiology, Middle Aged, Aged, Sex Factors, Treatment Outcome, Reoperation statistics & numerical data, Aortic Aneurysm, Thoracic surgery, Aortic Aneurysm, Thoracic mortality, Postoperative Complications epidemiology, Propensity Score, Aortic Dissection surgery, Aortic Dissection mortality, Registries
- Abstract
Objectives: Gender difference in the outcome after type A aortic dissection (TAAD) surgery remains an issue of ongoing debate. In this study, we aimed to evaluate the impact of gender on the short- and long-term outcome after surgery for TAAD., Methods: A multicentre European registry retrospectively included all consecutive TAAD surgery patients between 2005 and 2021 from 18 hospitals across 8 European countries. Early and late mortality, and cumulative incidence of aortic reoperation were compared between genders., Results: A total of 3902 patients underwent TAAD surgery, with 1185 (30.4%) being females. After propensity score matching, 766 pairs of males and females were compared. No statistical differences were detected in the early postoperative outcome between genders. Ten-year survival was comparable between genders (47.8% vs 47.1%; log-rank test, P = 0.679), as well as cumulative incidences of distal or proximal aortic reoperations. Ten-year relative survival compared to country-, year-, age- and sex-matched general population was higher among males (0.65) compared to females (0.58). The time-period subanalysis revealed advancements in surgical techniques in both genders over the years. However, an increase in stroke was observed over time for both populations, particularly among females., Conclusions: The past 16 years have witnessed marked advancements in surgical techniques for TAAD in both males and females, achieving comparable early and late mortality rates. Despite these findings, late relative survival was still in favour of males., (© The Author(s) 2024. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.)
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- 2024
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20. Femoral arterial cannulation for surgical repair of stanford type A aortic dissection.
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Juvonen T, Vendramin I, Mariscalco G, Jormalainen M, Perrotti A, Hervé A, Mazzaro E, Gatti G, Pettinari M, Peterss S, Buech J, Nappi F, Pinto AG, Rodriguez Lega J, Pol M, Rocek J, Kacer P, Rukosujew A, Wisniewski K, Piani D, Demal T, Conradi L, Ferrante L, Rinaldi M, Quintana E, Pruna-Guillen R, Gerelli S, Di Perna D, Fiore A, Folliguet T, Acharya M, El-Dean Z, Field M, Kuduvalli M, Onorati F, Francica A, Mäkikallio T, Dell'Aquila AM, Mustonen C, Raivio P, Rosato S, and Biancari F
- Subjects
- Aged, Female, Humans, Male, Middle Aged, Aortic Aneurysm, Thoracic surgery, Aortic Aneurysm, Thoracic mortality, Catheterization methods, Catheterization, Peripheral methods, Propensity Score, Retrospective Studies, Treatment Outcome, Aortic Dissection surgery, Aortic Dissection mortality, Femoral Artery surgery, Hospital Mortality
- Abstract
Background: The benefits and harms associated with femoral artery cannulation over other sites of arterial cannulation for surgical repair of acute Stanford type A aortic dissection (TAAD) are not conclusively established., Methods: We evaluated the outcomes after surgery for TAAD using femoral artery cannulation, supra-aortic arterial cannulation (i.e., innominate/subclavian/axillary artery cannulation), and direct aortic cannulation., Results: 3751 (96.1%) patients were eligible for this analysis. In-hospital mortality using supra-aortic arterial cannulation was comparable to femoral artery cannulation (17.8% vs. 18.4%; adjusted OR 0.846, 95% CI 0.799-1.202). This finding was confirmed in 1028 propensity score-matched pairs of patients with supra-aortic arterial cannulation or femoral artery cannulation (17.5% vs. 17.0%, p = 0.770). In-hospital mortality after direct aortic cannulation was lower compared to femoral artery cannulation (14.0% vs. 18.4%, adjusted OR 0.703, 95% CI 0.529-0.934). Among 583 propensity score-matched pairs of patients, direct aortic cannulation was associated with lower rates of in-hospital mortality (13.4% vs. 19.6%, p = 0.004) compared to femoral artery cannulation. Switching of the primary site of arterial cannulation was associated with increased rate of in-hospital mortality (36.5% vs. 17.0%; adjusted OR 2.730, 95% CI 1.564-4.765). Ten-year mortality was similar in the study cohorts., Conclusions: In this study, the outcomes of surgery for TAAD using femoral arterial cannulation were comparable to those using supra-aortic arterial cannulation. However, femoral arterial cannulation was associated with higher in-hospital mortality than direct aortic cannulation., Trial Registration: ClinicalTrials.gov registration code: NCT04831073., (© 2024 International Society of Surgery/Société Internationale de Chirurgie (ISS/SIC).)
- Published
- 2024
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