11,950 results on '"FETAL hemoglobin"'
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2. Associations between BCL11A and HBS1L-MYB polymorphisms and thalassemia risk
3. Exploring Novel Strategies to Alleviate Symptoms of β-Globinopathies: Examining the Potential Role of Embryonic ε-globin Induction
4. Genetic modifications of EGLN1 reactivate HbF production in β0-thalassemia/HbE
5. Association of ZBTB38 gene polymorphism (rs724016) with height and fetal hemoglobin in individuals with sickle cell anemia
6. Ex vivo culture resting time impacts transplantation outcomes of genome-edited human hematopoietic stem and progenitor cells in xenograft mouse models
7. Base editing of key residues in the BCL11A-XL-specific zinc finger domains derepresses fetal globin expression
8. Characterization of a cohort of Angolan children with sickle cell anemia treated with hydroxyurea
9. Transcriptional regulators of fetal hemoglobin
10. Activation of γ-globin expression by a common variant disrupting IKAROS-binding motif in β-thalassemia
11. Bach1 inhibitor HPP-D mediates γ-globin gene activation in sickle erythroid progenitors
12. Allogenic Cord Blood Transfusion in Preterm Infants
13. Proteomics screening uncovers HMGA1 as a promising negative regulator for γ-globin expression in response to decreased β-globin levels
14. Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of β-hemoglobinopathies
15. Fetal Hemoglobin Regulation in Beta-Thalassemia
16. Forced enhancer-promoter rewiring to alter gene expression in animal models
17. Genetic Modifiers of Sickle Cell Disease
18. New Treatments for Sickle Cell Disease.
19. Living with Sickle Cell Disease.
20. Co-occurrence of oculocutaneous albinism type 2 and mild sickle cell disease explained by HbS/βthal genotype in an individual from the Democratic Republic of Congo
21. Fetal hemoglobin modulates neurocognitive performance in sickle cell anemia✰,✰✰
22. Epigenetic and Transcriptional Modulator Potential of Epigallocatechin-3-gallate and Genistein on Fetal Hemoglobin Reactivators Genes
23. Novel histone deacetylase inhibitor CT-101 induces γ-globin gene expression in sickle erythroid progenitors with targeted epigenetic effects
24. Zinc finger nuclease-mediated gene editing in hematopoietic stem cells results in reactivation of fetal hemoglobin in sickle cell disease.
25. Multiplex CRISPR/Cas9 genome editing in hematopoietic stem cells for fetal hemoglobin reinduction generates chromosomal translocations
26. Production of functional human fetal hemoglobin in Nicotiana benthamiana for development of hemoglobin-based oxygen carriers
27. Acyclovir induces fetal hemoglobin via downregulation of γ-globin repressors, BCL11A and SOX6 trans-acting factors
28. Association of HMIP1 C-893A polymorphism and disease severity in patients with sickle cell anemia
29. Benserazide racemate and enantiomers induce fetal globin gene expression in vivo: Studies to guide clinical development for beta thalassemia and sickle cell disease
30. Structural dynamics of the heme pocket and intersubunit coupling in the dimeric hemoglobin from Scapharca inaequivalvis.
31. Epigenetic inactivation of ERF reactivates γ-globin expression in β-thalassemia
32. MicroRNA expression patterns in HbE/β-thalassemia patients: The passwords to unlock fetal hemoglobin expression in β-hemoglobinopathies
33. ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression
34. Monoterpenes as therapeutic candidates to induce fetal hemoglobin synthesis and up-regulation of gamma-globin gene: An in vitro and in vivo investigation
35. Erythroid induction activity of Aquilegia fragrans and Aquilegia pubiflora and identification of compounds using liquid chromatography-tandem mass spectrometry
36. Potent and orally active purine-based fetal hemoglobin inducers for treating β-thalassemia and sickle cell disease
37. Epigenetic regulation of hemoglobin switching in non-human primates
38. Epigenetic activities in erythroid cell gene regulation
39. Changing the Story.
40. Tenofovir disoproxil fumarate induces fetal hemoglobin production in K562 cells and β-YAC transgenic mice: A therapeutic approach for γ-globin induction
41. The association of HBG2, BCL11A, and HBS1L-MYB polymorphisms to thalidomide response in Chinese β-thalassemia patients
42. ATF4 Regulates MYB to Increase γ-Globin in Response to Loss of β-Globin
43. Preclinical Evaluation of a Novel Lentiviral Vector Driving Lineage-Specific BCL11A Knockdown for Sickle Cell Gene Therapy
44. The mRNA-Binding Protein IGF2BP1 Restores Fetal Hemoglobin in Cultured Erythroid Cells from Patients with β-Hemoglobin Disorders
45. Chapter 495 - Development of the Hematopoietic System
46. Conjugate prodrug AN-233 induces fetal hemoglobin expression in sickle erythroid progenitors and β-YAC transgenic mice
47. Integrative microRNA and gene expression analysis identifies new drug repurposing candidates for fetal hemoglobin induction in β-hemoglobinopathies
48. Targeted deletion of BCL11A gene by CRISPR-Cas9 system for fetal hemoglobin reactivation: A promising approach for gene therapy of beta thalassemia disease
49. Can we predict responsiveness to hypomethylating agents in AML?
50. Association of fetal hemoglobin level with frequency of acute pain episodes in sickle cell disease (HbS-only phenotype) patients
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