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Osteomalacia is a disorder of mineralization of newly formed osteoid that can be precipitated through mechanisms that result in hypocalcemia, such as prolonged vitamin D deficiency. Treatment is mainly focused on vitamin D supplementation; however, it can be largely ineffective in malabsorption syndromes. Targeted phototherapy is the localized delivery of ultraviolet light largely used in Dermatology to treat several skin diseases. It is also known that ultraviolet B radiation increases serum 25-hydroxyvitamin D levels. Although its role in the treatment of vitamin D deficiency is largely based on clinical experience, it should be considered, particularly in refractory cases. We report a 60-year-old female with osteomalacia secondary to vitamin D deficiency due to malabsorption after gastric bypass surgery. High dose supplementation of vitamin D and calcium was largely ineffective. Narrowband ultraviolet B was initiated resulting in marked clinical response and normalization of 25-hydroxyvitamin D serum levels. [ABSTRACT FROM AUTHOR]

Introduction: Atopic dermatitis is an increasingly studied immune-mediated disease. This study aims to identify the preferences of dermatologists in Colombia regarding diagnostic criteria, clinimetric scales, and preferred treatments for adults with atopic dermatitis. Methodology: This is an observational, descriptive, cross-sectional study. It was conducted through a virtual survey distributed during academic activities, following a pilot test. Results: A total of 68 dermatologists were surveyed. Of these, 29.3% base the diagnosis on clinical criteria, followed by Hanifin and Rajka criteria (23.08%). The most commonly used scales are DLQI, EASI, and clinical evaluation (29.85%). For mild disease, the first-line therapy is medium-potency corticosteroids (52.31%). As a second-line option, they prefer adjusting the potency of the corticosteroid (38.46%). The main reasons for initiating systemic therapy are clinical severity and severe impairment of quality of life. When choosing systemic therapy, clinical severity and drug efficacy are considered. For moderate-to-severe AD, the first choice is phototherapy (59.38%) followed by systemic corticosteroids (25%). As a second choice, cyclosporine (25%), phototherapy (18.75%), and azathioprine (18.75%) are preferred. Conclusions: This is the first study of its kind in Latin America. It found that there is no consensus on the diagnosis and management of the disease. In some cases, the necessary time to observe a clinical response is not being respected. The study provides unique information about the treatment of atopic dermatitis and suggests conducting academic activities to unify concepts among specialists. [ABSTRACT FROM AUTHOR]

Copyright of Opuntia Brava is the property of Universidad de Ciencias Pedagogicas de Las Tunas, Centro de Documentacion e Informacion Pedagogica and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

RESUMO Objetivo avaliar o estado comportamental de recém-nascidos pré-termo tardios sob a fototerapia e sua associação com a sucção não nutritiva. Métodos estudo transversal, realizado em uma maternidade pública de ensino, referência na gestação de alto risco e integrante da Iniciativa Hospital Amigo da Criança. Amostra por conveniência, composta por 60 recém-nascidos pré-termo tardios, assistidos em Alojamento Conjunto, divididos em dois grupos: um grupo composto por 30 recém-nascidos sob fototerapia (grupo caso) e outro grupo com 30 recém-nascidos que não estavam sob fototerapia (grupo controle). Os dados de caracterização da amostra foram obtidos por meio de anamnese e de coleta em prontuário médico/hospitalar. A avaliação do estado comportamental e da sucção não nutritiva foi realizada por meio da Preterm Oral Feeding Readiness Assessment Scale. As análises foram realizadas pelo software Jamovi (versão 2.4.1). O nível de significância de 5% foi adotado para todas as análises. Resultados verificou-se diferença significativa em que os recém-nascidos do grupo caso apresentaram escores inferiores no estado de organização comportamental e de sucção não nutritiva. Observou-se, ainda, significância na associação entre o estado comportamental e a sucção não nutritiva nos dois grupos. Conclusão recém-nascidos pré-termo tardios em fototerapia apresentam menores escores no estado de organização comportamental e nas respostas da sucção não nutritiva quando comparados aos recém-nascidos pré-termo tardios que não estavam submetidos ao tratamento. Observou-se associação entre as respostas da sucção não nutritiva e o estado de organização comportamental nos dois grupos.

Introduction: Photodynamic Therapy has been an important ally in tissue repair, with positive effects in the treatment of wounds and infections. Objective: To analyze the effects of the Healing Acceleration Methodology (MAC®) using propolis and toluidine blue on lower limb ulcers. Methods: Single-center, experimental, randomized and controlled study. Carried out between April 2021 and May 2022 at the outpatient clinic of the school clinic in a Brazilian capital. Patients were randomly assigned in a 1:1 ratio to receive photodynamic therapy (experimental group) or conventional dressing alone (control group). Patients over 18 years of age diagnosed with lower limb ulcers were included. Ten patients comprised the experimental group and 10 the control group. Patients were seen three times a week and monitored for two months. The primary outcome was the assessment of healing progress and the secondary outcome was the microscopic analysis of wound smears for the presence of cells and microorganisms. Results: In the experimental group, two wounds did not heal completely while in the control group, none of the 10 wounds healed completely during the 60-day follow-up. In the experimental group, 90% of patients did not have bacteria and fungi at the end of 30 days versus 40% in the control group. Conclusion: The present study showed that photodynamic therapy is a potential effective treatment in the healing process of lower limb ulcers. This can impact cost reduction and quality of life. Larger, well-designed studies are needed to corroborate the findings of the present study. [ABSTRACT FROM AUTHOR]

Copyright of Revista Foco (Interdisciplinary Studies Journal) is the property of Revista Foco and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista de la Facultad de Medicina Humana is the property of Instituto de Investigaciones en Ciencias Biomedicas de la Universidad Ricardo Palma and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)