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2. Multicancer screening test based on the detection of circulating non haematological proliferating atypical cells

Author

Malara, Natalia, Coluccio, Maria Laura, Grillo, Fabiana, Ferrazzo, Teresa, Garo, Nastassia C., Donato, Giuseppe, Lavecchia, Annamaria, Fulciniti, Franco, Sapino, Anna, Cascardi, Eliano, Pellegrini, Antonella, Foxi, Prassede, Furlanello, Cesare, Negri, Giovanni, Fadda, Guido, Capitanio, Arrigo, Pullano, Salvatore, Garo, Virginia M., Ferrazzo, Francesca, Lowe, Alarice, Torsello, Angela, Candeloro, Patrizio, and Gentile, Francesco

Published
2024
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5. Follicular Neoplasm

Author

Auger, Manon, Callegari, Fabiano, Fadda, Guido, Hirokawa, Mitsuyoshi, Rooper, Lisa, Ali, Syed Z., editor, and VanderLaan, Paul A., editor

Published
2023
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6. Neoplasm

Author

Baloch, Zubair, Fadda, Guido, Griffith, Christopher C., Klijanienko, Jerzy, Krane, Jeffrey F., Layfield, Lester, Maleki, Zahra, Nayar, Ritu, Pusztaszeri, Marc P., Faquin, William C., editor, Rossi, Esther Diana, editor, Baloch, Zubair, editor, Barkan, Güliz A., editor, Foschini, Maria Pia, editor, Kurtycz, Daniel F.I., editor, Pusztaszeri, Marc P., editor, and Vielh, Philippe, editor

Published
2023
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10. High-Grade Urothelial Carcinoma (HGUC)

Author

Siddiqui, Momin T., Allison, Derek B., Fadda, Guido, Han, Jee-Young, McIntire, Patrick J., Owens, Christopher L., Tabatabai, Z. Laura, Tsuzuki, Toyonori, Zhang, Mingjuan Lisa, Wojcik, Eva M., editor, Kurtycz, Daniel F.I., editor, and Rosenthal, Dorothy L., editor

Published
2022
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16. Multifocality in thyroid lobectomy and completion thyroidectomy – a single tertiary center retrospective study

Author

Policardo, Federica, primary, Bruno, Carmine, additional, Tralongo, Pietro, additional, Vegni, Federica, additional, Feraco, Angela, additional, Zhang, Qianqian, additional, Padial-Urtueta, Belen, additional, Carlino, Angela, additional, Pontecorvi, Alfredo, additional, Fadda, Guido, additional, Raffaelli, Marco, additional, Larocca, Luigi Maria, additional, Pantanowitz, Liron, additional, and Rossi, Esther Diana, additional

Published
2024
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18. Programmed Cell Death Ligand 1 (PD-L1) Immunohistochemical Expression in Advanced Urothelial Bladder Carcinoma: An Updated Review with Clinical and Pathological Implications.

Author

Germanà, Emanuela, Pepe, Ludovica, Pizzimenti, Cristina, Ballato, Mariagiovanna, Pierconti, Francesco, Tuccari, Giovanni, Ieni, Antonio, Giuffrè, Giuseppe, Fadda, Guido, Fiorentino, Vincenzo, and Martini, Maurizio

Subjects
PROGRAMMED death-ligand 1, TRANSITIONAL cell carcinoma, IMMUNE checkpoint proteins, IMMUNE checkpoint inhibitors, URODYNAMICS, CANCER patients, BREAST
Abstract

The management of advanced bladder carcinoma involves a multidisciplinary approach, but the prognosis remains poor for many patients. The immune system plays a crucial role in this disease, influencing both tumor development and response to treatment, and exploiting the immune system against the tumor can be a valuable strategy to destroy neoplastic cells. This is the biological principle underlying Bacillus Calmette–Guérin (BCG) use and, more recently, immune checkpoint inhibitors (ICIs), like PD-1 (programmed death-1)/PD-L1 (programmed death-ligand 1) inhibitors. In fact, one of the best studied immune checkpoints is represented by the PD-1/PD-L1 axis, which is a well-known immune escape system adopted by neoplastic bladder cells. PD-L1 expression has been associated with a higher pathologic stage and has shown prognostic value in bladder carcinoma. Interestingly, high-grade bladder cancers tend to express higher levels of PD-1 and PD-L1, suggesting a potential role of such an axis in mediating disease progression. Immunotherapy with PD-1 and PD-L1 inhibitors has therefore emerged as a valuable treatment option and has shown efficacy in advanced bladder cancer patients, with high PD-L1 expression levels associated with better treatment responses. Our review aims to provide a comprehensive overview of the role of PD-L1 in advanced bladder cancer, focusing on its implications for treatment decisions and the prediction of treatment response. Overall, our work aims to contribute to the understanding of PD-L1 as a predictive biomarker and highlight its role in shaping therapeutic approaches for advanced bladder cancer. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Contributors

Author

Abraham, Devaprabu, primary, Abraham, Nikita R., additional, Agarwal, Amit, additional, Ahadi, Mahsa S., additional, Alameer, Ehab, additional, Alobuia, Wilson, additional, Alon, Eran E., additional, Angkoon, Anuwong, additional, Al-Qurayshi, Zaid, additional, Angell, Trevor E., additional, Angelos, Peter, additional, Baek, Jung Hwan, additional, Baloch, Zubair W., additional, Barczyński, Marcin, additional, Bauer, Andrew J., additional, Bellantone, Rocco, additional, Berdelou, Amandine, additional, Bergenfeltz, Anders, additional, Bernet, Victor J., additional, Bible, Keith C., additional, Bilezikian, John Paul, additional, Bonilla-Velez, Juliana, additional, Boucai, Laura, additional, Brent, Gregory A., additional, Breuskin, Ingrid, additional, Brierley, James Duncan, additional, Brisebois, Simon, additional, Brooks, Jennifer, additional, Brumund, Kevin T., additional, Bura, Mijenko, additional, Alvarez, Jean Gabriel Bustamante, additional, Carneiro-Pla, Denise, additional, Cernea, Claudio R., additional, Chang, Rita Yuk-kwan, additional, Chen, Amy, additional, Chiang, Feng-Yu, additional, Chintakuntlawar, Ashish V., additional, Cho, Nancy L., additional, Chung, Woong Youn, additional, Cibas, Edmund S., additional, Dacey, Carolyn, additional, Davies, Louise, additional, De Crea, Carmela, additional, Delbridge, Leigh, additional, Diercks, Gillian, additional, Doherty, Gerard M., additional, Dralle, Henning, additional, Duh, Quan-Yang, additional, Dunlap, Quinn Alexander, additional, Durante, Cosmio, additional, Eltelety, Ahmad Mohamed, additional, Evans, Douglas B., additional, Fadda, Guido, additional, Faquin, William C., additional, Felger, Erin, additional, Ferris, Robert L., additional, Filetti, Sebastiano, additional, Freeman, Jeremy L., additional, Fundakowski, Christopher, additional, Ganly, Ian, additional, Gigliotti, Benjamin Joseph, additional, Gill, Anthony J., additional, Giordano, Thomas J., additional, Giuliani, Meredith E., additional, Gooi, Zhen, additional, Gopal, Raj K., additional, Guerlain, Joanne, additional, Hadoux, Julien, additional, Hales, Nathan, additional, Hartl, Dana, additional, Haugen, Bryan R., additional, Haymart, Megan R., additional, Inabnet, William B., additional, Irish, Jonathan, additional, Iwata, Ayaka, additional, Kamani, Dipti, additional, Kandil, Emad, additional, Kaplan, Edwin L., additional, Kazahaya, Ken, additional, Kebebew, Electron, additional, Kim, Matthew I., additional, Kovatch, Kevin J., additional, Lang, Brian H.H., additional, Leboulleux, Sophie, additional, Leung, Angela M., additional, Levine, Robert A., additional, Liddy, Whitney, additional, LiVolsi, Virginia A., additional, Lombardi, Celestino Pio, additional, Lubitz, Carrie C., additional, Machens, Andreas, additional, Maghami, Ellie, additional, Mandel, Susan J., additional, Maniakas, Anastasios, additional, Mathisen, Douglas J., additional, Mathur, Aarti, additional, Merati, Albert, additional, Milas, Mira, additional, Miyauchi, Akira, additional, Monteiro, Eric, additional, Netterville, James L., additional, Nikiforov, Yuri E., additional, Orloff, Lisa A., additional, Pandian, T.K., additional, Parangi, Sareh, additional, Parikh, Sanjay, additional, Park, Auh Whan, additional, Pearce, Elizabeth N., additional, Pellitteri, Phillip K., additional, Pennestrì, Francesco, additional, Pradhan, Roma, additional, Prichard, Ruth, additional, Raffaelli, Marco, additional, Randolph, Gregory W., additional, Rastatter, Jeff, additional, Reid, Lisa M., additional, Richer, Sara L., additional, Richmon, Jeremy D., additional, Ringel, Matthew D., additional, Roman, Benjamin R., additional, Romanchishen, Anatoly F., additional, Ross, Douglas S., additional, Russell, Jonathon O., additional, Russell, Marika D., additional, Ryder, Mabel, additional, Sabra, Mona M., additional, Sachdeva, Uma M., additional, Sadow, Peter M., additional, Scharpf, Joseph, additional, Schlumberger, Martin, additional, Schneider, Rick, additional, Scott-Coombes, David, additional, Sewell, Andrew B., additional, Shah, Jatin, additional, Shah, Manisha H., additional, Shindo, Maisie, additional, Shonka, David, additional, Silverberg, Shonni Joy, additional, Sims, John Randall, additional, Sinclair, Catherine F., additional, Singer, Michael C., additional, Siperstein, Allan E., additional, Sipos, Jennifer A., additional, Slough, Cristian Martin, additional, Sosa, Julie A., additional, Soylu, Selen, additional, Stack, Brendan C., additional, Stathatos, Nikolaos, additional, Stechman, Michael James, additional, Stephen, Antonia E., additional, Steward, David L., additional, Suh, Hyun, additional, Sywak, Mark, additional, Tang, Alice, additional, Terris, David J., additional, Thompson, Geoffrey Bruce, additional, Tolley, Neil, additional, Tominaga, Yoshihiro, additional, Triponez, Frédéric, additional, Tsang, Richard W., additional, Tuttle, R. Michael, additional, Urken, Mark L., additional, Vabalayte, Kristina V., additional, Vahabzadeh-Hagh, Andrew M., additional, Volpi, Erivelto Martinho, additional, Wang, Tracy S., additional, Wu, Che-Wei, additional, Wirth, Lori J., additional, Witterick, Ian, additional, Wong, Richard J., additional, Woodson, Gayle E., additional, Wright, Cameron D., additional, Zafereo, Mark E., additional, and Zubiaur, Fermin M., additional

Published
2021
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25. Neoplasm

Author

Baloch, Zubair, Fadda, Guido, Fırat, Pınar, Klijanienko, Jerzey, Krane, Jeffrey F., Layfield, Lester, Nayar, Ritu, Powers, Celeste N., Pusztaszeri, Marc, Faquin, William C., editor, Rossi, Esther Diana, editor, Baloch, Zubair, editor, Barkan, Güliz A., editor, Foschini, Maria P., editor, Kurtycz, Daniel F.I., editor, Pusztaszeri, Marc, editor, and Vielh, Philippe, editor

Published
2018
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28. Mucoepidermoid carcinoma, acinic cell carcinoma, and adenoid cystic carcinoma on fine-needle aspiration biopsy and The Milan System: an international multi-institutional study

Author

Miller, James A., An, Daniel, Shafique, Khurram, Song, Sharon, Rao, Rema A., Viswanathan, Kartik, Eykman, Elizabeth, Wiles, Austin, Ali, Syed Z., Field, Andrew, Fadda, Guido, Barkan, Guliz A., Layfield, Lester J., Rossi, Esther D., Powers, Celeste N., Siddiqui, Momin T., Kholova, Ivana, Baloch, Zubair, and Maleki, Zahra

Published
2019
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30. Unusual localization and clinical presentation of primary central nervous system extranodal marginal zone B‑cell lymphoma: A case report

Author

Fiorentino, Vincenzo, primary, Pizzimenti, Cristina, additional, Pierconti, Francesco, additional, Lentini, Maria, additional, Ieni, Antonio, additional, Caffo, Maria, additional, Angileri, Filippo, additional, Tuccari, Giovanni, additional, Fadda, Guido, additional, Martini, Maurizio, additional, and Larocca, Luigi, additional

Published
2023
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31. Delphi expert consensus for whole slide imaging in thyroid cytopathology

Author

Marletta, Stefano, primary, Salatiello, Maria, additional, Pantanowitz, Liron, additional, Bellevicine, Claudio, additional, Bongiovanni, Massimo, additional, Bonoldi, Emanuela, additional, De Rezende, Gisele, additional, Fadda, Guido, additional, Incardona, Paolo, additional, Munari, Enrico, additional, Pagni, Fabio, additional, Rossi, Esther Diana, additional, Tallini, Giovanni, additional, Troncone, Giancarlo, additional, Ugolini, Clara, additional, Vigliar, Elena, additional, and Eccher, Albino, additional

Published
2023
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32. Updates from Our Institutional Experience with Thyroid Nodules Diagnosed as Metastases

Author

Rossi, Esther Diana, primary, Bruno, Carmine, additional, Tralongo, Pietro, additional, Policardo, Federica, additional, Vegni, Federica, additional, Feraco, Angela, additional, Zhang, Qianqian, additional, Pontecorvi, Alfredo, additional, Fadda, Guido, additional, Lombardi, Celestino Pio, additional, Raffaelli, Marco, additional, Mulè, Antonino, additional, and Larocca, Luigi Maria, additional

Published
2023
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33. Digital Examination of LYmph node CYtopathology Using the Sydney system (DELYCYUS): An international, multi‐institutional study

Author

Caputo, Alessandro, primary, Fraggetta, Filippo, additional, Cretella, Pasquale, additional, Cozzolino, Immacolata, additional, Eccher, Albino, additional, Girolami, Ilaria, additional, Marletta, Stefano, additional, Troncone, Giancarlo, additional, Vigliar, Elena, additional, Acanfora, Gennaro, additional, Zarra, Karen Villar, additional, Torres Rivas, Héctor Enrique, additional, Fadda, Guido, additional, Field, Andrew, additional, Katz, Ruth, additional, Vielh, Philippe, additional, Eloy, Catarina, additional, Rajwanshi, Arvind, additional, Gupta, Nalini, additional, Al‐Abbadi, Mousa, additional, Bustami, Nadwa, additional, Arar, Tala, additional, Calaminici, Maria, additional, Raine, Juliet I., additional, Barroca, Helena, additional, Canão, Pedro Amoroso, additional, Ehinger, Mats, additional, Rajabian, Nilofar, additional, Dey, Pranab, additional, Medeiros, L. Jeffrey, additional, El Hussein, Siba, additional, Lin, Oscar, additional, D’Antonio, Antonio, additional, Bode‐Lesniewska, Beata, additional, Rossi, Esther Diana, additional, and Zeppa, Pio, additional

Published
2023
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39. Cytology of Head and Neck Lesions

Author

Schmitt, Fernando C., Rossi, Esther Diana, Iglesias, Carmela, Fadda, Guido, Cardesa, Antonio, editor, Slootweg, Pieter J., editor, Gale, Nina, editor, and Franchi, Alessandro, editor

Published
2016
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40. High-Grade Urothelial Carcinoma (HGUC)

Author

Siddiqui, Momin T., Fadda, Guido, Han, Jee-Young, Owens, Christopher L., Tabatabai, Z. Laura, Tsuzuki, Toyonori, Rosenthal, Dorothy L., editor, Wojcik, Eva M., editor, and Kurtycz, Daniel F.I., editor

Published
2016
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42. Update regarding the role of PD-L1 in oncocytic thyroid lesions on cytological samples.

Author

Dell'Aquila, Marco, Tralongo, Pietro, Granitto, Alessia, Martini, Maurizio, Capodimonti, Sara, Curatolo, Mariangela, Fiorentino, Vincenzo, Pontecorvi, Alfredo, Fadda, Guido, Lombardi, Celestino Pio, Raffaelli, Maco, Pantanowitz, Liron, Larocca, Luigi Maria, and Rossi, Esther Diana

Subjects
PROGRAMMED cell death 1 receptors, IMMUNOGLOBULINS, THYROID gland, PROGRAMMED death-ligand 1
Published
2023
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44. To Obtain More With Less: Cytologic Samples With Ancillary Molecular Techniques--The Useful Role of Liquid-Based Cytology

Author

Martini, Maurizio, Capodimonti, Sara, Cenci, Tonia, Bilotta, Mirna, Fadda, Guido, Larocca, Luigi Maria, and Rossi, Esther Diana

Subjects
Cytology -- Research, Gene expression -- Research, Liquids -- Research, Tumors -- Diagnosis -- Genetic aspects -- Research, Health
Abstract

* Context.--Fine-needle aspiration cytology has been increasingly used as the first tool in the evaluation of several diseases. Although cytology has a relevant role in the discrimination between benign and malignant lesions, conventional slides cannot lead to 100% conclusive results. It was hoped that the introduction of liquid-based cytology (LBC) would improve the efficacy of cytology through standardization, quality improvement, and the possibility of carrying out ancillary techniques on the residual stored material. In recent decades, the application of genomic alterations has been studied on cytologic samples with feasible and reliable results. The molecular analysis offers a powerful aid to define the best clinical or surgical approaches and follow-up for patients. In recent years, the application of different ancillary techniques has been carried out on conventional slides even though LBC represents a useful additional and alternative method for molecular testing.Objective.--To demonstrate the relevance of LBC as a valid aid to overcoming the difficulties encountered in the application of ancillary techniques on conventional slides.Data Sources.--We examined and reviewed our experience with the application of ancillary techniques on LBC performed on different body sites.Conclusions.--We emphasize that LBC achieves significant and accurate results. It represents a valid method for cytologic evaluation and it provides highly reproducible and informative molecular yields.(Arch Pathol Lab Med. 2018;142:299-307; doi: 10.5858/arpa.2017-0148-RA), The application of ancillary techniques has become an integral part of the management of several tumors. (1-3) In fact, the knowledge of the molecular mechanisms that are linked to the [...]

Published
2018
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46. Data from FOXA1 Is a Potential Oncogene in Anaplastic Thyroid Carcinoma

Author

Nucera, Carmelo, primary, Eeckhoute, Jerome, primary, Finn, Stephen, primary, Carroll, Jason S., primary, Ligon, Azra H., primary, Priolo, Carmen, primary, Fadda, Guido, primary, Toner, Mary, primary, Sheils, Orla, primary, Attard, Marco, primary, Pontecorvi, Alfredo, primary, Nose, Vânia, primary, Loda, Massimo, primary, and Brown, Myles, primary

Published
2023
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49. Digital Examination of LYmph node CYtopathology Using the Sydney system (DELYCYUS). An international, multi-institutional study

Author

Caputo, Alessandro, Fraggetta, Filippo, Cretella, Pasquale, Cozzolino, Immacolata, Eccher, Albino, Girolami, Ilaria, Marletta, Stefano, Troncone, Giancarlo, Vigliar, Elena, Acanfora, Gennaro, Zarra, Karen Villar, Torres Rivas, Héctor Enrique, Fadda, Guido, Field, Andrew, Katz, Ruth, Vielh, Philippe, Eloy, Catarina, Rajwanshi, Arvind, Gupta, Nalini, Al-Abbadi, Mousa, Bustami, Nadwa, Arar, Tala, Calaminici, Maria, Raine, Juliet I, Barroca, Helena, Canão, Pedro Amoroso, Ehinger, Mats, Rajabian, Nilofar, Dey, Pranab, Medeiros, L Jeffrey, El Hussein, Siba, Lin, Oscar, D'Antonio, Antonio, Bode-Lesniewska, Beata, Rossi, Esther Diana, and Zeppa, Pio

Subjects
whole-slide imaging, digital cytopathology, lymph node, reproducibility, virtual microscopy
Published
2023

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