Search

Your search keyword '"Faksri, Kiatichai"' showing total 237 results
Start Over Author "Faksri, Kiatichai"
237 results on '"Faksri, Kiatichai"'

9. Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing

Author

Allix-Béguec, Caroline, Arandjelovic, Irena, Bi, Lijun, Beckert, Patrick, Bonnet, Maryline, Bradley, Phelim, Cabibbe, Andrea M, Cancino-Muñoz, Irving, Caulfield, Mark J, Chaiprasert, Angkana, Cirillo, Daniela, Clifton, David, Comas, Iñaki, Crook, Derrick W, De Filippo, Maria Rosaria, de Neeling, Han, Diel, Roland, Drobniewski, Francis A, Faksri, Kiatichai, Farhat, Maha R, Fleming, Joy, Fowler, Philip, Fowler, Tom A, Gao, Qian, Gardy, Jennifer, Gascoyne-Binzi, Deborah, Cruz, Ana Gibertoni, Gil-Brusola, Ana, Golubchik, Tanya, Gonzalo, Ximena, Grandjean, Louis, He, Guangxue, Guthrie, Jennifer L, Hoosdally, Sarah, Hunt, Martin, Iqbal, Zamin, Ismail, Nazir, Johnston, James, Khanzada, Faisal Masood, Khor, Chiea Chuen, Kohl, Thomas A, Kong, Clare, Lipworth, Sam, Liu, Qingyun, Maphalala, Gugu, Martinez, Elena, Mathys, Vanessa, Merker, Matthias, Miotto, Paolo, Mistry, Nerges, Moore, David, Murray, Megan, Niemann, Stefan, Ong, Rick Twee-Hee, Peto, Tim EA, Posey, James E, Prammananan, Therdsak, Pym, Alexander, Rodrigues, Camilla, Rodrigues, Mabel, Rodwell, Timothy, Rossolini, Gian Maria, Padilla, Elisabeth Sánchez, Schito, Marco, Shen, Xin, Shendure, Jay, Sintchenko, Vitali, Sloutsky, Alex, Smith, E Grace, Snyder, Matthew, Soetaert, Karine, Starks, Angela M, Supply, Philip, Suriyapol, Prapat, Tahseen, Sabira, Tang, Patrick, Teo, Yik-Ying, Thuong, Thuong Nguyen Thuy, Thwaites, Guy, Tortoli, Enrico, Omar, Shaheed Vally, van Soolingen, Dick, Walker, A Sarah, Walker, Timothy M, Wilcox, Mark, Wilson, Daniel J, Wyllie, David, Yang, Yang, Zhang, Hongtai, Zhao, Yanlin, and Zhu, Baoli

Subjects
Genetics, Human Genome, Tuberculosis, Clinical Research, Patient Safety, Prevention, Rare Diseases, Infectious Diseases, Antimicrobial Resistance, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, Antitubercular Agents, Drug Resistance, Bacterial, Ethambutol, Genome, Bacterial, Genotype, Humans, Isoniazid, Microbial Sensitivity Tests, Mutation, Mycobacterium tuberculosis, Phenotype, Pyrazinamide, Rifampin, Whole Genome Sequencing, CRyPTIC Consortium and the 100, 000 Genomes Project, Medical and Health Sciences, General & Internal Medicine
Abstract

BackgroundThe World Health Organization recommends drug-susceptibility testing of Mycobacterium tuberculosis complex for all patients with tuberculosis to guide treatment decisions and improve outcomes. Whether DNA sequencing can be used to accurately predict profiles of susceptibility to first-line antituberculosis drugs has not been clear.MethodsWe obtained whole-genome sequences and associated phenotypes of resistance or susceptibility to the first-line antituberculosis drugs isoniazid, rifampin, ethambutol, and pyrazinamide for isolates from 16 countries across six continents. For each isolate, mutations associated with drug resistance and drug susceptibility were identified across nine genes, and individual phenotypes were predicted unless mutations of unknown association were also present. To identify how whole-genome sequencing might direct first-line drug therapy, complete susceptibility profiles were predicted. These profiles were predicted to be susceptible to all four drugs (i.e., pansusceptible) if they were predicted to be susceptible to isoniazid and to the other drugs or if they contained mutations of unknown association in genes that affect susceptibility to the other drugs. We simulated the way in which the negative predictive value changed with the prevalence of drug resistance.ResultsA total of 10,209 isolates were analyzed. The largest proportion of phenotypes was predicted for rifampin (9660 [95.4%] of 10,130) and the smallest was predicted for ethambutol (8794 [89.8%] of 9794). Resistance to isoniazid, rifampin, ethambutol, and pyrazinamide was correctly predicted with 97.1%, 97.5%, 94.6%, and 91.3% sensitivity, respectively, and susceptibility to these drugs was correctly predicted with 99.0%, 98.8%, 93.6%, and 96.8% specificity. Of the 7516 isolates with complete phenotypic drug-susceptibility profiles, 5865 (78.0%) had complete genotypic predictions, among which 5250 profiles (89.5%) were correctly predicted. Among the 4037 phenotypic profiles that were predicted to be pansusceptible, 3952 (97.9%) were correctly predicted.ConclusionsGenotypic predictions of the susceptibility of M. tuberculosis to first-line drugs were found to be correlated with phenotypic susceptibility to these drugs. (Funded by the Bill and Melinda Gates Foundation and others.).

Published
2018

12. Clusters of Drug-Resistant Mycobacterium tuberculosis Detected by Whole-Genome Sequence Analysis of Nationwide Sample, Thailand, 2014-2017

Author

Nonghanphithak, Ditthawat, Chaiprasert, Angkana, Smithtikarn, Saijai, Kamolwat, Phalin, Pungrassami, Petchawan, Chongsuvivatwong, Virasakdi, Mahasirimongkol, Surakameth, Reechaipichitkul, Wipa, Leepiyasakulchai, Chaniya, Phelan, Jody E., Blair, David, Clark, Taane G., and Faksri, Kiatichai

Subjects
Nucleotide sequencing -- Usage, Drug resistance in microorganisms -- Distribution, DNA sequencing -- Usage, Tuberculosis -- Risk factors -- Distribution, Cluster analysis -- Methods, Mycobacterium tuberculosis -- Genetic aspects -- Distribution, Company distribution practices, Health
Abstract

Tuberculosis (TB), caused by Mycobacterium tuberculosis, is a major global public health issue. Southeast Asia contributes notably (44%) to global TB cases. Thailand is in the top 30 countries for [...]

Published
2021
Full Text
View/download PDF

15. Antibodies against SARS-CoV-2 in unvaccinated children hospitalized with COVID-19: An observational cohort study of pre-Omicron and Omicron variants era.

Author

Uppala, Rattapon, Sitthikarnkha, Phanthila, Faksri, Kiatichai, Kosalaraksa, Pope, Techasatian, Leelawadee, Tantawarak, Nattakarn, and Nanthavongsa, Sysavanh

Subjects
SARS-CoV-2 Omicron variant, HOSPITAL care of children, SARS-CoV-2, COVID-19, COVID-19 pandemic, COUGH
Abstract

Purpose: This study aimed to investigate the antibodies against SARS-CoV-2 in children hospitalized due to COVID-19 during the era of pre-Omicron and Omicron variants. Methods: This was a retrospective observational study conducted at a tertiary academic medical center in Thailand between June 2021 and August 2022. We collected the data of children aged under 18-year who were hospitalized from SARS‐CoV‐2 infection. After hospital discharge, we scheduled clinical follow-up 60 to 90 days post-infection clinical follow-up. We measured antibodies against SARS-CoV-2 anti-spike protein receptor-binding domain in the serum during a follow-up visit and compared the mean difference of antibody levels between children infected with COVID-19 during the pre-Omicron and Omicron eras. Results: A total of 119 children enrolled into the study. There were 58 and 61 children hospitalized due to COVID-19 during pre-Omicron and Omicron era, respectively. The median (interquartile range, IQR) of SARS-CoV-2 antibodies in all cases was 206.1 (87.9–424.1) U/mL at follow-up. Children infected during pre-Omicron had SARS-CoV-2 antibody levels at follow-up higher than children infected during Omicron era [mean difference 292.57 U/mL, 95% CI 53.85–531.28, p = 0.017). There was no difference in SARS-CoV-2 antibody levels between the children based on gender, age, co-morbidities, chest radiograph classification, or diagnosis. Conclusions: The antibodies response to SARS-CoV-2 infection was weaker during the Omicron era than previous variant of concern. Immunization strategies and policies should be implemented in children even if they had been previously infected. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

24. A Hybrid LSTM and MLP Scheme for COVID-19 Prediction: A Case Study in Thailand.

Author

Kompunt, Peerapol, Yongjoh, Suparat, Aimtongkham, Phet, Muneesawang, Paisarn, Faksri, Kiatichai, and Chakchai So-In

Subjects
COVID-19 pandemic, WEB-based user interfaces, MULTILAYER perceptrons, RECESSIONS, TIME series analysis, HUMAN resources departments
Abstract

After the COVID-19 epidemic, Thailand was affected in a variety of ways, with the most obvious being the economic downturn and the huge impact on health, including the loss of medical and human resources to combat the epidemic. However, Thailand still lacks analysis and prediction tools required to prepare for future epidemic situations. Therefore, we present development models for predicting the spread of the COVID-19 epidemic. In particular, the application of a long short-term memory (LSTM) and multilayer perceptron (MLP) model was investigated to predict new cases, total cases, new deaths, and total deaths. There are a total of 77 provinces in Thailand. The data used in this trial were obtained from the Department of Disease Control (DDC) of the Thai government. The modeling employed 2 types of data: dynamic (time series) and static. There were 2 phases: 1) the LSTM was used to manipulate time series data and 2) the MLP model was used to manipulate static data. Then, the models were merged for further analysis. We evaluated the performance of the combined model, yielding an accuracy of 99.72 % based on R2 values, higher than the values obtained for state-of-the-art methods. In addition, the prediction results can be further combined with GIS data in each province and displayed via an easy-to-use web application for mapping. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

27. High clustering rate and genotypic drug-susceptibility screening for the newly recommended anti-tuberculosis drugs among global extensively drug-resistant Mycobacterium tuberculosis isolates

Author

Trisakul, Kanwara, primary, Nonghanphithak, Ditthawat, additional, Chaiyachat, Pratchakan, additional, Kaewprasert, Orawee, additional, Sakmongkoljit, Kankanon, additional, Reechaipichitkul, Wipa, additional, Chaiprasert, Angkana, additional, Blair, David, additional, Clark, Taane G., additional, and Faksri, Kiatichai, additional

Published
2022
Full Text
View/download PDF

28. High rate of reinfection and possible transmission of Mycobacterium avium complex in Northeast Thailand

Author

Boonjetsadaruhk, Wicharajit, primary, Kaewprasert, Orawee, additional, Nithichanon, Arnone, additional, Ananta, Pimjai, additional, Chaimanee, Prajuab, additional, Salao, Kanin, additional, Phoksawat, Wisitsak, additional, Laohaviroj, Marut, additional, Sirichoat, Auttawit, additional, Fong, Yang, additional, Wongwajana, Suwin, additional, Namwat, Wises, additional, Lulitanond, Viraphong, additional, Chetchotisakd, Ploenchan, additional, and Faksri, Kiatichai, additional

Published
2022
Full Text
View/download PDF

30. The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: a genotypic analysis

Author

Walker, Timothy M, primary, Miotto, Paolo, additional, Köser, Claudio U, additional, Fowler, Philip W, additional, Knaggs, Jeff, additional, Iqbal, Zamin, additional, Hunt, Martin, additional, Chindelevitch, Leonid, additional, Farhat, Maha R, additional, Cirillo, Daniela Maria, additional, Comas, Iñaki, additional, Posey, James, additional, Omar, Shaheed V, additional, Peto, Timothy EA, additional, Suresh, Anita, additional, Uplekar, Swapna, additional, Laurent, Sacha, additional, Colman, Rebecca E, additional, Nathanson, Carl-Michael, additional, Zignol, Matteo, additional, Walker, Ann Sarah, additional, Crook, Derrick W, additional, Ismail, Nazir, additional, Rodwell, Timothy C, additional, Walker, A Sarah, additional, Steyn, Adrie J C, additional, Lalvani, Ajit, additional, Baulard, Alain, additional, Christoffels, Alan, additional, Mendoza-Ticona, Alberto, additional, Trovato, Alberto, additional, Skrahina, Alena, additional, Lachapelle, Alexander S, additional, Brankin, Alice, additional, Piatek, Amy, additional, Gibertoni Cruz, Ana, additional, Koch, Anastasia, additional, Cabibbe, Andrea Maurizio, additional, Spitaleri, Andrea, additional, Brandao, Angela P, additional, Chaiprasert, Angkana, additional, Barbova, Anna, additional, Van Rie, Annelies, additional, Ghodousi, Arash, additional, Bainomugisa, Arnold, additional, Mandal, Ayan, additional, Roohi, Aysha, additional, Javid, Babak, additional, Zhu, Baoli, additional, Letcher, Brice, additional, Rodrigues, Camilla, additional, Nimmo, Camus, additional, NATHANSON, Carl-Michael, additional, Duncan, Carla, additional, Coulter, Christopher, additional, Utpatel, Christian, additional, Liu, Chunfa, additional, Grazian, Clara, additional, Kong, Clare, additional, Wilson, Daniel J, additional, Matias, Daniela, additional, Jorgensen, Danielle, additional, Zimenkov, Danila, additional, Chetty, Darren, additional, Moore, David AJ, additional, Clifton, David A, additional, van Soolingen, Dick, additional, Liu, Dongxin, additional, Kohlerschmidt, Donna, additional, Barreira, Draurio, additional, Ngcamu, Dumisani, additional, Santos Lazaro, Elias David, additional, Kelly, Ellis, additional, Borroni, Emanuele, additional, Roycroft, Emma, additional, Andre, Emmanuel, additional, Böttger, Erik C, additional, Robinson, Esther, additional, Menardo, Fabrizio, additional, Mendes, Flavia F, additional, Jamieson, Frances B, additional, Coll, Francesc, additional, Gao, George Fu, additional, Kasule, George W, additional, Rossolini, Gian Maria, additional, Rodger, Gillian, additional, Smith, E Grace, additional, Meintjes, Graeme, additional, Thwaites, Guy, additional, Hoffmann, Harald, additional, Albert, Heidi, additional, Cox, Helen, additional, Laurenson, Ian F, additional, Arandjelovic, Irena, additional, Barilar, Ivan, additional, Robledo, Jaime, additional, Millard, James, additional, Johnston, James, additional, Posey, Jamie, additional, Andrews, Jason R, additional, Gardy, Jennifer, additional, Guthrie, Jennifer, additional, Taylor, Jill, additional, Werngren, Jim, additional, Metcalfe, John, additional, Coronel, Jorge, additional, Shea, Joseph, additional, Carter, Joshua, additional, Pinhata, Juliana MW, additional, Kus, Julianne V, additional, Todt, Katharina, additional, Holt, Kathryn, additional, Nilgiriwala, Kayzad S, additional, Ghisi, Kelen T, additional, Malone, Kerri M, additional, Faksri, Kiatichai, additional, Musser, Kimberlee A, additional, Joseph, Lavania, additional, Rigouts, Leen, additional, Jarrett, Lisa, additional, Grandjean, Louis, additional, Ferrazoli, Lucilaine, additional, Rodrigues, Mabel, additional, Farhat, Maha, additional, Schito, Marco, additional, Fitzgibbon, Margaret M, additional, Loembé, Marguerite Massinga, additional, Wijkander, Maria, additional, Ballif, Marie, additional, Rabodoarivelo, Marie-Sylvianne, additional, Mihalic, Marina, additional, WILCOX, Mark, additional, ZIGNOL, Matteo, additional, Merker, Matthias, additional, Egger, Matthias, additional, O'Donnell, Max, additional, Caws, Maxine, additional, Wu, Mei-Hua, additional, Whitfield, Michael G, additional, Inouye, Michael, additional, Mansjö, Mikael, additional, Dang Thi, Minh Ha, additional, Joloba, Moses, additional, Kamal, SM Mostofa, additional, Okozi, Nana, additional, ISMAIL, Nazir, additional, Mistry, Nerges, additional, Hoang, Nhung N, additional, Rakotosamimanana, Niaina, additional, Paton, Nicholas I, additional, Rancoita, Paola M V, additional, Lapierre, Pascal, additional, Hall, Patricia J, additional, Tang, Patrick, additional, Claxton, Pauline, additional, Wintringer, Penelope, additional, Keller, Peter M, additional, Thai, Phan Vuong Khac, additional, Supply, Philip, additional, Srilohasin, Prapaporn, additional, Suriyaphol, Prapat, additional, Rathod, Priti, additional, Kambli, Priti, additional, Groenheit, Ramona, additional, Ong, Rick Twee-Hee, additional, Warren, Robin M, additional, Wilkinson, Robert J, additional, Diel, Roland, additional, Oliveira, Rosangela S, additional, Khot, Rukhsar, additional, Jou, Ruwen, additional, Tahseen, Sabira, additional, Gharbia, Saheer, additional, Kouchaki, Samaneh, additional, Shah, Sanchi, additional, Plesnik, Sara, additional, Earle, Sarah G, additional, Dunstan, Sarah, additional, Hoosdally, Sarah J, additional, Mitarai, Satoshi, additional, Gagneux, Sebastien, additional, Yao, Shen-Yuan, additional, Grandjean Lapierre, Simon, additional, Battaglia, Simone, additional, Niemann, Stefan, additional, Pandey, Sushil, additional, Halse, Tanya A, additional, Cohen, Ted, additional, Cortes, Teresa, additional, Prammananan, Therdsak, additional, Kohl, Thomas A, additional, Thuong, Nguyen T T, additional, Teo, Tik Ying, additional, Peto, Timothy E A, additional, William, Timothy, additional, Walker, Timothy M, additional, Rogers, Thomas R, additional, Surve, Utkarsha, additional, Mathys, Vanessa, additional, Furió, Victoria, additional, Cook, Victoria, additional, Vijay, Srinivasan, additional, Escuyer, Vincent, additional, Dreyer, Viola, additional, Sintchenko, Vitali, additional, Saphonn, Vonthanak, additional, Solano, Walter, additional, Lin, Wan-Hsuan, additional, van Gemert, Wayne, additional, He, Wencong, additional, Yang, Yang, additional, Zhao, Yanlin, additional, Qin, Youwen, additional, Xiao, Yu-Xin, additional, Hasan, Zahra, additional, and Puyen, Zully M, additional

Published
2022
Full Text
View/download PDF

34. Whole-genome analysis of drug-resistant Mycobacterium tuberculosis reveals novel mutations associated with fluoroquinolone resistance

Author

Chaiyachat, Pratchakan, primary, Chaiprasert, Angkana, additional, Nonghanphithak, Ditthawat, additional, Smithtikarn, Saijai, additional, Kamolwat, Phalin, additional, Pungrassami, Petchawan, additional, Reechaipichitkul, Wipa, additional, Ong, Rick Twee-Hee, additional, Teo, Yik-Ying, additional, and Faksri, Kiatichai, additional

Published
2021
Full Text
View/download PDF

38. New iridoid glucosides from the roots of Rothmannia wittii (Craib) Bremek.

Author

Wisetsai, Awat, Schevenels, Florian T., Faksri, Kiatichai, Tontapha, Sarawut, Amornkitbamrung, Vittaya, and Lekphrom, Ratsami

Subjects
GLUCOSIDES, RUBIACEAE
Abstract

Phytochemical investigation of the roots of Rothmannia wittii led to the isolation of three new iridoid glucosides, named rothmanniosides A–C (1–3), and nine known compounds (4–12). Their structures, including their absolute configurations, were elucidated by thorough analysis of mass spectrometric and NMR spectroscopic data, together with CD calculations. Compounds 4 and 11 are reported from the Rubiaceae family for the first time. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

43. PmrB mutations including a novel 10-amino acid repeat sequence insertion associated with low-level colistin resistance in carbapenem-resistant Acinetobacter baumannii

Author

Lunha, Kamonwan, primary, Thet, Khin Thet, additional, Ngudsuntia, Arisa, additional, Charoensri, Nicha, additional, Lulitanond, Aroonlug, additional, Tavichakorntrakool, Ratree, additional, Wonglakorn, Lumyai, additional, Faksri, Kiatichai, additional, and Chanawong, Aroonwadee, additional

Published
2020
Full Text
View/download PDF

44. 24-locus MIRU-VNTR and Spoligotyping analysis of drug-resistant Mycobacterium tuberculosis strains isolated from Northeastern Thailand

Author

Rueangsak, Kulrattana, primary, Tanuchit, Sonvanee, additional, Chumpol, Jaluporn, additional, Kamhorm, Sawian, additional, Ngoenpramual, Montira, additional, Namwat, Wises, additional, Faksri, Kiatichai, additional, Wilailuckana, Chotechana, additional, Pinlaor, Porntip, additional, and Sangka, Arunnee, additional

Published
2020
Full Text
View/download PDF

50. Genomic evidence supporting the clonal expansion of extensively drug-resistant tuberculosis bacteria belonging to a rare proto-Beijing genotype

Author

Srilohasin, Prapaporn, primary, Prammananan, Therdsak, additional, Faksri, Kiatichai, additional, Phelan, Jody E., additional, Suriyaphol, Prapat, additional, Kamolwat, Phalin, additional, Smithtikarn, Saijai, additional, Disratthakit, Areeya, additional, Regmi, Sanjib Mani, additional, Leechawengwongs, Manoon, additional, Twee-Hee Ong, Rick, additional, Teo, Yik Ying, additional, Tongsima, Sissades, additional, Clark, Taane G., additional, and Chaiprasert, Angkana, additional

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results