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31 results on '"Fan, Jia-Hao"'

4. An $O^*(1.84^k)$ Parameterized Algorithm for the Multiterminal Cut Problem

Author

Cao, Yixin, Chen, Jianer, and Fan, Jia-Hao

Subjects
Computer Science - Data Structures and Algorithms
Abstract

We study the \emph{multiterminal cut} problem, which, given an $n$-vertex graph whose edges are integer-weighted and a set of terminals, asks for a partition of the vertex set such that each terminal is in a distinct part, and the total weight of crossing edges is at most $k$. Our weapons shall be two classical results known for decades: \emph{maximum volume minimum ($s,t$)-cuts} by [Ford and Fulkerson, \emph{Flows in Networks}, 1962] and \emph{isolating cuts} by [Dahlhaus et al., \emph{SIAM J. Comp.} 23(4):864-894, 1994]. We sharpen these old weapons with the help of submodular functions, and apply them to this problem, which enable us to design a more elaborated branching scheme on deciding whether a non-terminal vertex is with a terminal or not. This bounded search tree algorithm can be shown to run in $1.84^k\cdot n^{O(1)}$ time, thereby breaking the $2^k\cdot n^{O(1)}$ barrier. As a by-product, it gives a $1.36^k\cdot n^{O(1)}$ time algorithm for $3$-terminal cut. The preprocessing applied on non-terminal vertices might be of use for study of this problem from other aspects., Comment: To fulfill the request of the European Research Council (ERC)

Published
2017
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9. Complexity Analysis of Balloon Drawing for Rooted Trees

Author

Lin, Chun-Cheng, Yen, Hsu-Chun, Poon, Sheung-Hung, and Fan, Jia-Hao

Subjects
Computer Science - Computational Geometry, Computer Science - Computational Complexity, Computer Science - Data Structures and Algorithms
Abstract

In a balloon drawing of a tree, all the children under the same parent are placed on the circumference of the circle centered at their parent, and the radius of the circle centered at each node along any path from the root reflects the number of descendants associated with the node. Among various styles of tree drawings reported in the literature, the balloon drawing enjoys a desirable feature of displaying tree structures in a rather balanced fashion. For each internal node in a balloon drawing, the ray from the node to each of its children divides the wedge accommodating the subtree rooted at the child into two sub-wedges. Depending on whether the two sub-wedge angles are required to be identical or not, a balloon drawing can further be divided into two types: even sub-wedge and uneven sub-wedge types. In the most general case, for any internal node in the tree there are two dimensions of freedom that affect the quality of a balloon drawing: (1) altering the order in which the children of the node appear in the drawing, and (2) for the subtree rooted at each child of the node, flipping the two sub-wedges of the subtree. In this paper, we give a comprehensive complexity analysis for optimizing balloon drawings of rooted trees with respect to angular resolution, aspect ratio and standard deviation of angles under various drawing cases depending on whether the tree is of even or uneven sub-wedge type and whether (1) and (2) above are allowed. It turns out that some are NP-complete while others can be solved in polynomial time. We also derive approximation algorithms for those that are intractable in general.

Published
2010

15. Parameterized and Approximation Algorithms for the MAF Problem in Multifurcating Trees

Author

Chen, Jianer, Fan, Jia-Hao, Sze, Sing-Hoi, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Brandstädt, Andreas, editor, Jansen, Klaus, editor, and Reischuk, Rüdiger, editor

Published
2013
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16. An O *(1.84 k ) Parameterized Algorithm for the Multiterminal Cut Problem

Author

Cao, Yixin, Chen, Jianer, Fan, Jia-Hao, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Gąsieniec, Leszek, editor, and Wolter, Frank, editor

Published
2013
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17. Multicut in Trees Viewed through the Eyes of Vertex Cover

Author

Chen, Jianer, Fan, Jia-Hao, Kanj, Iyad A., Liu, Yang, Zhang, Fenghui, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Nierstrasz, Oscar, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Sudan, Madhu, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Vardi, Moshe Y., Series editor, Weikum, Gerhard, Series editor, Dehne, Frank, editor, Iacono, John, editor, and Sack, Jörg-Rüdiger, editor

Published
2011
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18. Width-Optimal Visibility Representations of Plane Graphs

Author

Fan, Jia-Hao, Lin, Chun-Cheng, Lu, Hsueh-I, Yen, Hsu-Chun, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, and Tokuyama, Takeshi, editor

Published
2007
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30. [High-intensity laser therapy combined with targeted hand function training for the treatment of grade 1-2 thumb carpometacarpal osteoarthritis].

Author

Guo Q, Zhang ZM, Fan JH, Zhu JY, and Wei XL

Subjects
Humans, Female, Middle Aged, Aged, Aged, 80 and over, Thumb, Braces, Pain, Laser Therapy, Osteoarthritis therapy
Abstract

Objective: To explore clinical effect of high-intensity laser therapy(HILT) combined with targeted hand function training on pain and lateral pinch force in grade 1-2 thumb carpometacarpal(CMC) osteoarthritis(OA)., Methods: From April 2020 and April 2022, 42 female patients with thumb CMC OA grade 1 to 2, aged from 58 to 80 years old with an everage of (68.90±7.58) years old were divided into observation group of 21 patients who received HILT and targeted hand function training for 4 weeks, and 21 patients in control group who received ultrashort wave therapy combined with using of an orthosis for 4 weeks. Visual analogue scale(VAS) was applied to evaluate degree of pain, function of finger was evaluated by dynamometer to measure lateral pinch force at baseline, immediately following intervention at 4 and 12 weeks following intervention., Results: VAS and lateral pinch force at immediately and 12 weeks after intervention betwwen two groups were better than that of before intervention( P <0.05). Compared with control group, the degree of pain in observation group improved more(immediately after intervention t =3.37, P <0.05, 12 weeks after intervention t =9.05, P <0.05), lateral pinch force higher than that of control group (immediately after intervention t =-2.55, P <0.05, 12 weeks after intervention t =9.51, P <0.05)., Conclusion: High-intensity laser therapy combined with targeted hand function training is more effective than traditional methods in improving pain and lateral pinch force in grade 1-2 thumb carpometacarpal osteoarthritis.

Published
2023
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31. Association of genetic polymorphisms in CD8+ T cell inhibitory genes and susceptibility to and progression of chronic HBV infection.

Author

Peng H, Li QL, Hou SH, Hu J, Fan JH, and Guo JJ

Subjects
Adult, Aged, Alleles, Antigens, CD genetics, Apoptosis Regulatory Proteins genetics, Bcl-2-Like Protein 11, CD8-Positive T-Lymphocytes immunology, Case-Control Studies, Disease Progression, Female, Gene Frequency, Genetic Association Studies, Genotype, Haplotypes, Hepatitis B virus, Hepatitis B, Chronic immunology, Hepatitis B, Chronic pathology, Humans, Liver Function Tests, Male, Membrane Proteins genetics, Middle Aged, Odds Ratio, Polymorphism, Single Nucleotide, Programmed Cell Death 1 Receptor genetics, Proto-Oncogene Proteins genetics, Receptors, Immunologic genetics, Signaling Lymphocytic Activation Molecule Family, Viral Load, CD8-Positive T-Lymphocytes metabolism, Genetic Predisposition to Disease, Hepatitis B, Chronic genetics, Hepatitis B, Chronic virology, Immunomodulation genetics, Polymorphism, Genetic
Abstract

Background: Previous studies have shown that multiple inhibitory genes play an important role in HBV-specific CD8+ T cell exhaustion and dysfunction in the setting of chronic HBV infection. Polymorphic variants of these genes are thought to be predisposing factors for HBV susceptibility, clearance, and disease progression. The aim of this retrospective study was to identify variants affecting chronic HBV infection in a Chinese Han population., Methods: We chose 28 tgSNPs from HapMap data on 5 key genes. They were genotyped on a total of 858 chronic HBV patients, 429 patients who underwent spontaneous recovery, and 239 healthy controls. We evaluated the correlation between the polymorphisms and HBV susceptibility, spontaneous clearance, and disease progression., Results: The association of rs3827537 of BIM genotype TA and allele A was significantly different (P=0.016, OR=2.049; P=0.031, OR=1.925) between HBV patients and healthy controls. The rs36084323 of PD-1, as well as rs3766377, rs485618, rs4656942 of CD244 showed significant associations with the risk for HBV-related cirrhosis and hepatocellular carcinoma (HCC) (P=0.009, OR=0.482; P=0.009, OR=4.573; P=0.015, OR=0.580; P=0.028, OR=2.855). MDR analysis revealed that the four SNPs (rs36084323, rs3766377, rs485618, rs4656942) modulated the predisposition to cirrhosis and HCC in patients with chronic HBV infection (P=0.006). Using a luciferase reporter assay, we demonstrated that various alleles of rs3766377 had differential effects, and rs3766377 and rs485618 might have interactive effects., Conclusions: The present study reveals genetic associations among PD-1 and CD244 variants that may be involved in the development of cirrhosis and HCC in patients with chronic HBV infection. The BIM variant was associated with HBV susceptibility., (Copyright © 2015 Elsevier B.V. All rights reserved.)

Published
2015
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