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The indoor thermal and humid environment of the solar greenhouse, especially the air humidity, is studied by the field test and psychrometric chart. First, the air temperature and relative humidity, and solar radiation in the greenhouse were tested by field tests. According to the test results, Solar radiation has a great influence on the air temperature and relative humidity in the greenhouse. The air temperature and relative humidity in a greenhouse vary dramatically in the presence of solar radiation. At night, although the indoor air temperature meets the requirements of crop growth, indoor relative humidity is close to 90%, far higher than the suitable relative humidity area (60-65%). Then, the night air condition was analyzed based on the psychrometric chart. Indoor air does not need to be dehumidified, but could be heated to the greenhouse to reduce the relative humidity. Finally, the variation of indoor air humidity ratio was analyzed. Solar radiation and natural ventilation are important factors affecting the variation of the humidity ratio of indoor air in the solar greenhouse. During the test period, solar radiation increases the humidity ratio of indoor air, and natural ventilation reduces the humidity ratio of indoor air in the solar greenhouse.

With the rapid development of greenhouses, the indoor air quality, particularly airborne microorganisms, is closely related to the health of farmers and needs more attention. In this study, the concentrations of airborne fungi at seedling, fruiting and harvesting stages in typical tomatoes greenhouses were tested. Temperature, relative humidity and the microbial concentrations were analysed. It was found that the dominant fungal genera are Aspergillus and Cladosporium, no matter it was in which growth stage. Ventilation is an effective way to reduce the concentrations of airborne fungi through dilution and decrease the relative humidity.

We report a peptidic dual-targeting drug delivery platform (integrins targeting and self-assembly instructed by matrix metalloproteinases) towards inflamed endothelial cells, which improved the anti-inflammatory ability of the loaded drug (i.e., puerarin) in vitro and thus improved the antiatherogenic effect of the loaded drug (i.e., puerarin) in vivo. [ABSTRACT FROM AUTHOR]

Yes‐associated protein (YAP), a major effector of the Hippo signalling pathway, is widely implicated in vascular pathophysiology processes. Here, we identify a new role of YAP in the regulation of vascular senescence. The inhibition or deficiency and overexpression of YAP were performed in human umbilical vein endothelial cells (HUVECs) and isolated vascular tissues. Cellular and vascular senescence was assessed by analysis of the senescence‐associated β‐galactosidase (SA‐β‐gal) and expression of senescence markers P16, P21, P53, TERT and TRF1. We found that YAP was highly expressed in old vascular tissues, inhibition and knockdown of YAP decreased senescence, while overexpression of YAP increased the senescence in both HUVECs and vascular tissues. In addition, autophagic flux blockage and mTOR pathway activation were observed during YAP‐induced HUVECs and vascular senescence, which could be relieved by the inhibition and knockdown of YAP. Moreover, YAP‐promoted cellular and vascular senescence could be relieved by mTOR inhibition. Collectively, our findings indicate that YAP may serve as a potential therapeutic target for ageing‐associated cardiovascular disease. [ABSTRACT FROM AUTHOR]

Objective: To investigate whether intraindividual variability of fasting glucose (FG) in young adulthood is associated with coronary artery calcification (CAC) progression in middle age.Research Design and Methods: We included 2,256 CARDIA (Coronary Artery Risk Development Study in Young Adults) participants with CAC assessment by computed tomography scanner at baseline (2000-2001) and 10 years later (2010-2011). CAC progression was assessed for each individual as the difference of logarithmic CAC scores at follow-up and baseline (log[CAC (follow-up) + 1] - log[CAC (baseline) + 1]). FG variability was defined by the coefficient of variation about the mean FG (FG-CV), the SD of FG (FG-SD), and the average real variability of FG (FG-ARV) during the 10-year follow-up. We investigated the association between FG variability and CAC progression with adjustment for demographics, clinical risk factors, mean FG level, change in FG level, diabetes incidence, and medication use.Results: After multivariable adjustment, 1-SD increment in FG-CV was associated with worse progression of CAC as demonstrated as percent change in CAC, with incident CAC 5.9% (95% CI 1.0, 10.7) and any CAC progression 6.7% (95% CI 2.3, 11.1) during 10 years. Similar findings were also observed in FG-SD and FG-ARV.Conclusions: Higher FG variability during young adulthood was associated with greater CAC progression in middle age, suggesting its value in predicting risk for subclinical coronary artery diseases. [ABSTRACT FROM AUTHOR]