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181 results on '"Fan, Youhong"'

1. Lung Cancer Models Reveal Severe Acute Respiratory Syndrome Coronavirus 2–Induced Epithelial-to-Mesenchymal Transition Contributes to Coronavirus Disease 2019 Pathophysiology

Author

Stewart, C. Allison, Gay, Carl M., Ramkumar, Kavya, Cargill, Kasey R., Cardnell, Robert J., Nilsson, Monique B., Heeke, Simon, Park, Elizabeth M., Kundu, Samrat T., Diao, Lixia, Wang, Qi, Shen, Li, Xi, Yuanxin, Zhang, Bingnan, Della Corte, Carminia Maria, Fan, Youhong, Kundu, Kiran, Gao, Boning, Avila, Kimberley, Pickering, Curtis R., Johnson, Faye M., Zhang, Jianjun, Kadara, Humam, Minna, John D., Gibbons, Don L., Wang, Jing, Heymach, John V., and Byers, Lauren Averett

Published
2021
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2. STING Pathway Expression Identifies NSCLC With an Immune-Responsive Phenotype

Author

Della Corte, Carminia M., Sen, Triparna, Gay, Carl M., Ramkumar, Kavya, Diao, Lixia, Cardnell, Robert J., Rodriguez, Bertha Leticia, Stewart, C. Allison, Papadimitrakopoulou, Vassiliki A., Gibson, Laura, Fradette, Jared J., Wang, Qi, Fan, Youhong, Peng, David H., Negrao, Marcelo V., Wistuba, Ignacio I., Fujimoto, Junya, Solis Soto, Luisa M., Behrens, Carmen, Skoulidis, Ferdinandos, Heymach, John V., Wang, Jing, Gibbons, Don L., and Byers, Lauren A.

Published
2020
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3. Combination Treatment of the Oral CHK1 Inhibitor, SRA737, and Low-Dose Gemcitabine Enhances the Effect of Programmed Death Ligand 1 Blockade by Modulating the Immune Microenvironment in SCLC

Author

Sen, Triparna, Della Corte, Carminia M., Milutinovic, Snezana, Cardnell, Robert J., Diao, Lixia, Ramkumar, Kavya, Gay, Carl M., Stewart, C. Allison, Fan, Youhong, Shen, Li, Hansen, Ryan J., Strouse, Bryan, Hedrick, Michael P., Hassig, Christian A., Heymach, John V., Wang, Jing, and Byers, Lauren A.

Published
2019
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7. Supplementary Table S1 from CD38-Mediated Immunosuppression as a Mechanism of Tumor Cell Escape from PD-1/PD-L1 Blockade

Author

Chen, Limo, primary, Diao, Lixia, primary, Yang, Yongbin, primary, Yi, Xiaohui, primary, Rodriguez, B. Leticia, primary, Li, Yanli, primary, Villalobos, Pamela A., primary, Cascone, Tina, primary, Liu, Xi, primary, Tan, Lin, primary, Lorenzi, Philip L., primary, Huang, Anfei, primary, Zhao, Qiang, primary, Peng, Di, primary, Fradette, Jared J., primary, Peng, David H., primary, Ungewiss, Christin, primary, Roybal, Jonathon, primary, Tong, Pan, primary, Oba, Junna, primary, Skoulidis, Ferdinandos, primary, Peng, Weiyi, primary, Carter, Brett W., primary, Gay, Carl M., primary, Fan, Youhong, primary, Class, Caleb A., primary, Zhu, Jingfen, primary, Rodriguez-Canales, Jaime, primary, Kawakami, Masanori, primary, Byers, Lauren Averett, primary, Woodman, Scott E., primary, Papadimitrakopoulou, Vassiliki A., primary, Dmitrovsky, Ethan, primary, Wang, Jing, primary, Ullrich, Stephen E., primary, Wistuba, Ignacio I., primary, Heymach, John V., primary, Qin, F. Xiao-Feng, primary, and Gibbons, Don L., primary

Published
2023
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8. Data from Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer

Author

Sen, Triparna, primary, Rodriguez, B. Leticia, primary, Chen, Limo, primary, Corte, Carminia M. Della, primary, Morikawa, Naoto, primary, Fujimoto, Junya, primary, Cristea, Sandra, primary, Nguyen, Thuyen, primary, Diao, Lixia, primary, Li, Lerong, primary, Fan, Youhong, primary, Yang, Yongbin, primary, Wang, Jing, primary, Glisson, Bonnie S., primary, Wistuba, Ignacio I., primary, Sage, Julien, primary, Heymach, John V., primary, Gibbons, Don L., primary, and Byers, Lauren A., primary

Published
2023
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9. Data from AXL Inhibition Suppresses the DNA Damage Response and Sensitizes Cells to PARP Inhibition in Multiple Cancers

Author

Balaji, Kavitha, primary, Vijayaraghavan, Smruthi, primary, Diao, Lixia, primary, Tong, Pan, primary, Fan, Youhong, primary, Carey, Jason P.W., primary, Bui, Tuyen N., primary, Warner, Steve, primary, Heymach, John V., primary, Hunt, Kelly K., primary, Wang, Jing, primary, Byers, Lauren Averett, primary, and Keyomarsi, Khandan, primary

Published
2023
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10. Data from Co-occurring Genomic Alterations Define Major Subsets of KRAS-Mutant Lung Adenocarcinoma with Distinct Biology, Immune Profiles, and Therapeutic Vulnerabilities

Author

Skoulidis, Ferdinandos, primary, Byers, Lauren A., primary, Diao, Lixia, primary, Papadimitrakopoulou, Vassiliki A., primary, Tong, Pan, primary, Izzo, Julie, primary, Behrens, Carmen, primary, Kadara, Humam, primary, Parra, Edwin R., primary, Canales, Jaime Rodriguez, primary, Zhang, Jianjun, primary, Giri, Uma, primary, Gudikote, Jayanthi, primary, Cortez, Maria A., primary, Yang, Chao, primary, Fan, Youhong, primary, Peyton, Michael, primary, Girard, Luc, primary, Coombes, Kevin R., primary, Toniatti, Carlo, primary, Heffernan, Timothy P., primary, Choi, Murim, primary, Frampton, Garrett M., primary, Miller, Vincent, primary, Weinstein, John N., primary, Herbst, Roy S., primary, Wong, Kwok-Kin, primary, Zhang, Jianhua, primary, Sharma, Padmanee, primary, Mills, Gordon B., primary, Hong, Waun K., primary, Minna, John D., primary, Allison, James P., primary, Futreal, Andrew, primary, Wang, Jing, primary, Wistuba, Ignacio I., primary, and Heymach, John V., primary

Published
2023
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11. Data from CD38-Mediated Immunosuppression as a Mechanism of Tumor Cell Escape from PD-1/PD-L1 Blockade

Author

Chen, Limo, primary, Diao, Lixia, primary, Yang, Yongbin, primary, Yi, Xiaohui, primary, Rodriguez, B. Leticia, primary, Li, Yanli, primary, Villalobos, Pamela A., primary, Cascone, Tina, primary, Liu, Xi, primary, Tan, Lin, primary, Lorenzi, Philip L., primary, Huang, Anfei, primary, Zhao, Qiang, primary, Peng, Di, primary, Fradette, Jared J., primary, Peng, David H., primary, Ungewiss, Christin, primary, Roybal, Jonathon, primary, Tong, Pan, primary, Oba, Junna, primary, Skoulidis, Ferdinandos, primary, Peng, Weiyi, primary, Carter, Brett W., primary, Gay, Carl M., primary, Fan, Youhong, primary, Class, Caleb A., primary, Zhu, Jingfen, primary, Rodriguez-Canales, Jaime, primary, Kawakami, Masanori, primary, Byers, Lauren Averett, primary, Woodman, Scott E., primary, Papadimitrakopoulou, Vassiliki A., primary, Dmitrovsky, Ethan, primary, Wang, Jing, primary, Ullrich, Stephen E., primary, Wistuba, Ignacio I., primary, Heymach, John V., primary, Qin, F. Xiao-Feng, primary, and Gibbons, Don L., primary

Published
2023
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12. Data from Enhanced Vulnerability of LKB1-Deficient NSCLC to Disruption of ATP Pools and Redox Homeostasis by 8-Cl-Ado

Author

Galan-Cobo, Ana, primary, Stellrecht, Christine M., primary, Yilmaz, Emrullah, primary, Yang, Chao, primary, Qian, Yu, primary, Qu, Xiao, primary, Akhter, Ishita, primary, Ayres, Mary L., primary, Fan, Youhong, primary, Tong, Pan, primary, Diao, Lixia, primary, Ding, Jie, primary, Giri, Uma, primary, Gudikote, Jayanthi, primary, Nilsson, Monique, primary, Wierda, William G., primary, Wang, Jing, primary, Skoulidis, Ferdinandos, primary, Minna, John D., primary, Gandhi, Varsha, primary, and Heymach, John V., primary

Published
2023
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13. Supplementary Figures S1 - S11 from Co-occurring Genomic Alterations Define Major Subsets of KRAS-Mutant Lung Adenocarcinoma with Distinct Biology, Immune Profiles, and Therapeutic Vulnerabilities

Author

Skoulidis, Ferdinandos, primary, Byers, Lauren A., primary, Diao, Lixia, primary, Papadimitrakopoulou, Vassiliki A., primary, Tong, Pan, primary, Izzo, Julie, primary, Behrens, Carmen, primary, Kadara, Humam, primary, Parra, Edwin R., primary, Canales, Jaime Rodriguez, primary, Zhang, Jianjun, primary, Giri, Uma, primary, Gudikote, Jayanthi, primary, Cortez, Maria A., primary, Yang, Chao, primary, Fan, Youhong, primary, Peyton, Michael, primary, Girard, Luc, primary, Coombes, Kevin R., primary, Toniatti, Carlo, primary, Heffernan, Timothy P., primary, Choi, Murim, primary, Frampton, Garrett M., primary, Miller, Vincent, primary, Weinstein, John N., primary, Herbst, Roy S., primary, Wong, Kwok-Kin, primary, Zhang, Jianhua, primary, Sharma, Padmanee, primary, Mills, Gordon B., primary, Hong, Waun K., primary, Minna, John D., primary, Allison, James P., primary, Futreal, Andrew, primary, Wang, Jing, primary, Wistuba, Ignacio I., primary, and Heymach, John V., primary

Published
2023
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14. Supplementary Methods from AXL Inhibition Suppresses the DNA Damage Response and Sensitizes Cells to PARP Inhibition in Multiple Cancers

Author

Balaji, Kavitha, primary, Vijayaraghavan, Smruthi, primary, Diao, Lixia, primary, Tong, Pan, primary, Fan, Youhong, primary, Carey, Jason P.W., primary, Bui, Tuyen N., primary, Warner, Steve, primary, Heymach, John V., primary, Hunt, Kelly K., primary, Wang, Jing, primary, Byers, Lauren Averett, primary, and Keyomarsi, Khandan, primary

Published
2023
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15. Supplementary Data from Enhanced Vulnerability of LKB1-Deficient NSCLC to Disruption of ATP Pools and Redox Homeostasis by 8-Cl-Ado

Author

Galan-Cobo, Ana, primary, Stellrecht, Christine M., primary, Yilmaz, Emrullah, primary, Yang, Chao, primary, Qian, Yu, primary, Qu, Xiao, primary, Akhter, Ishita, primary, Ayres, Mary L., primary, Fan, Youhong, primary, Tong, Pan, primary, Diao, Lixia, primary, Ding, Jie, primary, Giri, Uma, primary, Gudikote, Jayanthi, primary, Nilsson, Monique, primary, Wierda, William G., primary, Wang, Jing, primary, Skoulidis, Ferdinandos, primary, Minna, John D., primary, Gandhi, Varsha, primary, and Heymach, John V., primary

Published
2023
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16. Supplementary Table S1 from Co-occurring Genomic Alterations Define Major Subsets of KRAS-Mutant Lung Adenocarcinoma with Distinct Biology, Immune Profiles, and Therapeutic Vulnerabilities

Author

Skoulidis, Ferdinandos, primary, Byers, Lauren A., primary, Diao, Lixia, primary, Papadimitrakopoulou, Vassiliki A., primary, Tong, Pan, primary, Izzo, Julie, primary, Behrens, Carmen, primary, Kadara, Humam, primary, Parra, Edwin R., primary, Canales, Jaime Rodriguez, primary, Zhang, Jianjun, primary, Giri, Uma, primary, Gudikote, Jayanthi, primary, Cortez, Maria A., primary, Yang, Chao, primary, Fan, Youhong, primary, Peyton, Michael, primary, Girard, Luc, primary, Coombes, Kevin R., primary, Toniatti, Carlo, primary, Heffernan, Timothy P., primary, Choi, Murim, primary, Frampton, Garrett M., primary, Miller, Vincent, primary, Weinstein, John N., primary, Herbst, Roy S., primary, Wong, Kwok-Kin, primary, Zhang, Jianhua, primary, Sharma, Padmanee, primary, Mills, Gordon B., primary, Hong, Waun K., primary, Minna, John D., primary, Allison, James P., primary, Futreal, Andrew, primary, Wang, Jing, primary, Wistuba, Ignacio I., primary, and Heymach, John V., primary

Published
2023
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17. Supplementary Methods; Figures S1 - S22; Tables S2, S6, S9 - S12 from CD38-Mediated Immunosuppression as a Mechanism of Tumor Cell Escape from PD-1/PD-L1 Blockade

Author

Chen, Limo, primary, Diao, Lixia, primary, Yang, Yongbin, primary, Yi, Xiaohui, primary, Rodriguez, B. Leticia, primary, Li, Yanli, primary, Villalobos, Pamela A., primary, Cascone, Tina, primary, Liu, Xi, primary, Tan, Lin, primary, Lorenzi, Philip L., primary, Huang, Anfei, primary, Zhao, Qiang, primary, Peng, Di, primary, Fradette, Jared J., primary, Peng, David H., primary, Ungewiss, Christin, primary, Roybal, Jonathon, primary, Tong, Pan, primary, Oba, Junna, primary, Skoulidis, Ferdinandos, primary, Peng, Weiyi, primary, Carter, Brett W., primary, Gay, Carl M., primary, Fan, Youhong, primary, Class, Caleb A., primary, Zhu, Jingfen, primary, Rodriguez-Canales, Jaime, primary, Kawakami, Masanori, primary, Byers, Lauren Averett, primary, Woodman, Scott E., primary, Papadimitrakopoulou, Vassiliki A., primary, Dmitrovsky, Ethan, primary, Wang, Jing, primary, Ullrich, Stephen E., primary, Wistuba, Ignacio I., primary, Heymach, John V., primary, Qin, F. Xiao-Feng, primary, and Gibbons, Don L., primary

Published
2023
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18. Supplementary Methods, Table S2 from Co-occurring Genomic Alterations Define Major Subsets of KRAS-Mutant Lung Adenocarcinoma with Distinct Biology, Immune Profiles, and Therapeutic Vulnerabilities

Author

Skoulidis, Ferdinandos, primary, Byers, Lauren A., primary, Diao, Lixia, primary, Papadimitrakopoulou, Vassiliki A., primary, Tong, Pan, primary, Izzo, Julie, primary, Behrens, Carmen, primary, Kadara, Humam, primary, Parra, Edwin R., primary, Canales, Jaime Rodriguez, primary, Zhang, Jianjun, primary, Giri, Uma, primary, Gudikote, Jayanthi, primary, Cortez, Maria A., primary, Yang, Chao, primary, Fan, Youhong, primary, Peyton, Michael, primary, Girard, Luc, primary, Coombes, Kevin R., primary, Toniatti, Carlo, primary, Heffernan, Timothy P., primary, Choi, Murim, primary, Frampton, Garrett M., primary, Miller, Vincent, primary, Weinstein, John N., primary, Herbst, Roy S., primary, Wong, Kwok-Kin, primary, Zhang, Jianhua, primary, Sharma, Padmanee, primary, Mills, Gordon B., primary, Hong, Waun K., primary, Minna, John D., primary, Allison, James P., primary, Futreal, Andrew, primary, Wang, Jing, primary, Wistuba, Ignacio I., primary, and Heymach, John V., primary

Published
2023
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19. Supplementary Figure S1 Details from Co-occurring Genomic Alterations Define Major Subsets of KRAS-Mutant Lung Adenocarcinoma with Distinct Biology, Immune Profiles, and Therapeutic Vulnerabilities

Author

Skoulidis, Ferdinandos, primary, Byers, Lauren A., primary, Diao, Lixia, primary, Papadimitrakopoulou, Vassiliki A., primary, Tong, Pan, primary, Izzo, Julie, primary, Behrens, Carmen, primary, Kadara, Humam, primary, Parra, Edwin R., primary, Canales, Jaime Rodriguez, primary, Zhang, Jianjun, primary, Giri, Uma, primary, Gudikote, Jayanthi, primary, Cortez, Maria A., primary, Yang, Chao, primary, Fan, Youhong, primary, Peyton, Michael, primary, Girard, Luc, primary, Coombes, Kevin R., primary, Toniatti, Carlo, primary, Heffernan, Timothy P., primary, Choi, Murim, primary, Frampton, Garrett M., primary, Miller, Vincent, primary, Weinstein, John N., primary, Herbst, Roy S., primary, Wong, Kwok-Kin, primary, Zhang, Jianhua, primary, Sharma, Padmanee, primary, Mills, Gordon B., primary, Hong, Waun K., primary, Minna, John D., primary, Allison, James P., primary, Futreal, Andrew, primary, Wang, Jing, primary, Wistuba, Ignacio I., primary, and Heymach, John V., primary

Published
2023
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20. Supplementary Figures 1-7 and Tables 1 and 2 from AXL Inhibition Suppresses the DNA Damage Response and Sensitizes Cells to PARP Inhibition in Multiple Cancers

Author

Balaji, Kavitha, primary, Vijayaraghavan, Smruthi, primary, Diao, Lixia, primary, Tong, Pan, primary, Fan, Youhong, primary, Carey, Jason P.W., primary, Bui, Tuyen N., primary, Warner, Steve, primary, Heymach, John V., primary, Hunt, Kelly K., primary, Wang, Jing, primary, Byers, Lauren Averett, primary, and Keyomarsi, Khandan, primary

Published
2023
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21. Supplementary Materials from Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer

Author

Sen, Triparna, primary, Rodriguez, B. Leticia, primary, Chen, Limo, primary, Corte, Carminia M. Della, primary, Morikawa, Naoto, primary, Fujimoto, Junya, primary, Cristea, Sandra, primary, Nguyen, Thuyen, primary, Diao, Lixia, primary, Li, Lerong, primary, Fan, Youhong, primary, Yang, Yongbin, primary, Wang, Jing, primary, Glisson, Bonnie S., primary, Wistuba, Ignacio I., primary, Sage, Julien, primary, Heymach, John V., primary, Gibbons, Don L., primary, and Byers, Lauren A., primary

Published
2023
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22. Supplementary figure legend from KDR Amplification Is Associated with VEGF-Induced Activation of the mTOR and Invasion Pathways but does not Predict Clinical Benefit to the VEGFR TKI Vandetanib

Author

Nilsson, Monique B., primary, Giri, Uma, primary, Gudikote, Jayanthi, primary, Tang, Ximing, primary, Lu, Wei, primary, Tran, Hai, primary, Fan, Youhong, primary, Koo, Andrew, primary, Diao, Lixia, primary, Tong, Pan, primary, Wang, Jing, primary, Herbst, Roy, primary, Johnson, Bruce E., primary, Ryan, Andy, primary, Webster, Alan, primary, Rowe, Philip, primary, Wistuba, Ignacio I., primary, and Heymach, John V., primary

Published
2023
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23. Supplemental Figure 3 from An Integrated Molecular Analysis of Lung Adenocarcinomas Identifies Potential Therapeutic Targets among TTF1-Negative Tumors, Including DNA Repair Proteins and Nrf2

Author

Cardnell, Robert J.G., primary, Behrens, Carmen, primary, Diao, Lixia, primary, Fan, YouHong, primary, Tang, Ximing, primary, Tong, Pan, primary, Minna, John D., primary, Mills, Gordon B., primary, Heymach, John V., primary, Wistuba, Ignacio I., primary, Wang, Jing, primary, and Byers, Lauren A., primary

Published
2023
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24. Supplemental Table 1 from KDR Amplification Is Associated with VEGF-Induced Activation of the mTOR and Invasion Pathways but does not Predict Clinical Benefit to the VEGFR TKI Vandetanib

Author

Nilsson, Monique B., primary, Giri, Uma, primary, Gudikote, Jayanthi, primary, Tang, Ximing, primary, Lu, Wei, primary, Tran, Hai, primary, Fan, Youhong, primary, Koo, Andrew, primary, Diao, Lixia, primary, Tong, Pan, primary, Wang, Jing, primary, Herbst, Roy, primary, Johnson, Bruce E., primary, Ryan, Andy, primary, Webster, Alan, primary, Rowe, Philip, primary, Wistuba, Ignacio I., primary, and Heymach, John V., primary

Published
2023
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26. Supplementary Table 1 from An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

Author

Byers, Lauren Averett, primary, Diao, Lixia, primary, Wang, Jing, primary, Saintigny, Pierre, primary, Girard, Luc, primary, Peyton, Michael, primary, Shen, Li, primary, Fan, Youhong, primary, Giri, Uma, primary, Tumula, Praveen K., primary, Nilsson, Monique B., primary, Gudikote, Jayanthi, primary, Tran, Hai, primary, Cardnell, Robert J.G., primary, Bearss, David J., primary, Warner, Steven L., primary, Foulks, Jason M., primary, Kanner, Steven B., primary, Gandhi, Varsha, primary, Krett, Nancy, primary, Rosen, Steven T., primary, Kim, Edward S., primary, Herbst, Roy S., primary, Blumenschein, George R., primary, Lee, J. Jack, primary, Lippman, Scott M., primary, Ang, K. Kian, primary, Mills, Gordon B., primary, Hong, Waun K., primary, Weinstein, John N., primary, Wistuba, Ignacio I., primary, Coombes, Kevin R., primary, Minna, John D., primary, and Heymach, John V., primary

Published
2023
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27. Supplementary Methods from An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

Author

Byers, Lauren Averett, primary, Diao, Lixia, primary, Wang, Jing, primary, Saintigny, Pierre, primary, Girard, Luc, primary, Peyton, Michael, primary, Shen, Li, primary, Fan, Youhong, primary, Giri, Uma, primary, Tumula, Praveen K., primary, Nilsson, Monique B., primary, Gudikote, Jayanthi, primary, Tran, Hai, primary, Cardnell, Robert J.G., primary, Bearss, David J., primary, Warner, Steven L., primary, Foulks, Jason M., primary, Kanner, Steven B., primary, Gandhi, Varsha, primary, Krett, Nancy, primary, Rosen, Steven T., primary, Kim, Edward S., primary, Herbst, Roy S., primary, Blumenschein, George R., primary, Lee, J. Jack, primary, Lippman, Scott M., primary, Ang, K. Kian, primary, Mills, Gordon B., primary, Hong, Waun K., primary, Weinstein, John N., primary, Wistuba, Ignacio I., primary, Coombes, Kevin R., primary, Minna, John D., primary, and Heymach, John V., primary

Published
2023
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28. Supplementary Figure 3 from An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

Author

Byers, Lauren Averett, primary, Diao, Lixia, primary, Wang, Jing, primary, Saintigny, Pierre, primary, Girard, Luc, primary, Peyton, Michael, primary, Shen, Li, primary, Fan, Youhong, primary, Giri, Uma, primary, Tumula, Praveen K., primary, Nilsson, Monique B., primary, Gudikote, Jayanthi, primary, Tran, Hai, primary, Cardnell, Robert J.G., primary, Bearss, David J., primary, Warner, Steven L., primary, Foulks, Jason M., primary, Kanner, Steven B., primary, Gandhi, Varsha, primary, Krett, Nancy, primary, Rosen, Steven T., primary, Kim, Edward S., primary, Herbst, Roy S., primary, Blumenschein, George R., primary, Lee, J. Jack, primary, Lippman, Scott M., primary, Ang, K. Kian, primary, Mills, Gordon B., primary, Hong, Waun K., primary, Weinstein, John N., primary, Wistuba, Ignacio I., primary, Coombes, Kevin R., primary, Minna, John D., primary, and Heymach, John V., primary

Published
2023
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29. Supplemental Table 4 from An Integrated Molecular Analysis of Lung Adenocarcinomas Identifies Potential Therapeutic Targets among TTF1-Negative Tumors, Including DNA Repair Proteins and Nrf2

Author

Cardnell, Robert J.G., primary, Behrens, Carmen, primary, Diao, Lixia, primary, Fan, YouHong, primary, Tang, Ximing, primary, Tong, Pan, primary, Minna, John D., primary, Mills, Gordon B., primary, Heymach, John V., primary, Wistuba, Ignacio I., primary, Wang, Jing, primary, and Byers, Lauren A., primary

Published
2023
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30. Supplementary Figure 7 from An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

Author

Byers, Lauren Averett, primary, Diao, Lixia, primary, Wang, Jing, primary, Saintigny, Pierre, primary, Girard, Luc, primary, Peyton, Michael, primary, Shen, Li, primary, Fan, Youhong, primary, Giri, Uma, primary, Tumula, Praveen K., primary, Nilsson, Monique B., primary, Gudikote, Jayanthi, primary, Tran, Hai, primary, Cardnell, Robert J.G., primary, Bearss, David J., primary, Warner, Steven L., primary, Foulks, Jason M., primary, Kanner, Steven B., primary, Gandhi, Varsha, primary, Krett, Nancy, primary, Rosen, Steven T., primary, Kim, Edward S., primary, Herbst, Roy S., primary, Blumenschein, George R., primary, Lee, J. Jack, primary, Lippman, Scott M., primary, Ang, K. Kian, primary, Mills, Gordon B., primary, Hong, Waun K., primary, Weinstein, John N., primary, Wistuba, Ignacio I., primary, Coombes, Kevin R., primary, Minna, John D., primary, and Heymach, John V., primary

Published
2023
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31. Supplemental Figure 2 from KDR Amplification Is Associated with VEGF-Induced Activation of the mTOR and Invasion Pathways but does not Predict Clinical Benefit to the VEGFR TKI Vandetanib

Author

Nilsson, Monique B., primary, Giri, Uma, primary, Gudikote, Jayanthi, primary, Tang, Ximing, primary, Lu, Wei, primary, Tran, Hai, primary, Fan, Youhong, primary, Koo, Andrew, primary, Diao, Lixia, primary, Tong, Pan, primary, Wang, Jing, primary, Herbst, Roy, primary, Johnson, Bruce E., primary, Ryan, Andy, primary, Webster, Alan, primary, Rowe, Philip, primary, Wistuba, Ignacio I., primary, and Heymach, John V., primary

Published
2023
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32. Supplementary Figure 5 from An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

Author

Byers, Lauren Averett, primary, Diao, Lixia, primary, Wang, Jing, primary, Saintigny, Pierre, primary, Girard, Luc, primary, Peyton, Michael, primary, Shen, Li, primary, Fan, Youhong, primary, Giri, Uma, primary, Tumula, Praveen K., primary, Nilsson, Monique B., primary, Gudikote, Jayanthi, primary, Tran, Hai, primary, Cardnell, Robert J.G., primary, Bearss, David J., primary, Warner, Steven L., primary, Foulks, Jason M., primary, Kanner, Steven B., primary, Gandhi, Varsha, primary, Krett, Nancy, primary, Rosen, Steven T., primary, Kim, Edward S., primary, Herbst, Roy S., primary, Blumenschein, George R., primary, Lee, J. Jack, primary, Lippman, Scott M., primary, Ang, K. Kian, primary, Mills, Gordon B., primary, Hong, Waun K., primary, Weinstein, John N., primary, Wistuba, Ignacio I., primary, Coombes, Kevin R., primary, Minna, John D., primary, and Heymach, John V., primary

Published
2023
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33. Supplementary Table 2 from An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

Author

Byers, Lauren Averett, primary, Diao, Lixia, primary, Wang, Jing, primary, Saintigny, Pierre, primary, Girard, Luc, primary, Peyton, Michael, primary, Shen, Li, primary, Fan, Youhong, primary, Giri, Uma, primary, Tumula, Praveen K., primary, Nilsson, Monique B., primary, Gudikote, Jayanthi, primary, Tran, Hai, primary, Cardnell, Robert J.G., primary, Bearss, David J., primary, Warner, Steven L., primary, Foulks, Jason M., primary, Kanner, Steven B., primary, Gandhi, Varsha, primary, Krett, Nancy, primary, Rosen, Steven T., primary, Kim, Edward S., primary, Herbst, Roy S., primary, Blumenschein, George R., primary, Lee, J. Jack, primary, Lippman, Scott M., primary, Ang, K. Kian, primary, Mills, Gordon B., primary, Hong, Waun K., primary, Weinstein, John N., primary, Wistuba, Ignacio I., primary, Coombes, Kevin R., primary, Minna, John D., primary, and Heymach, John V., primary

Published
2023
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34. Supplementary Figure 4 from An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

Author

Byers, Lauren Averett, primary, Diao, Lixia, primary, Wang, Jing, primary, Saintigny, Pierre, primary, Girard, Luc, primary, Peyton, Michael, primary, Shen, Li, primary, Fan, Youhong, primary, Giri, Uma, primary, Tumula, Praveen K., primary, Nilsson, Monique B., primary, Gudikote, Jayanthi, primary, Tran, Hai, primary, Cardnell, Robert J.G., primary, Bearss, David J., primary, Warner, Steven L., primary, Foulks, Jason M., primary, Kanner, Steven B., primary, Gandhi, Varsha, primary, Krett, Nancy, primary, Rosen, Steven T., primary, Kim, Edward S., primary, Herbst, Roy S., primary, Blumenschein, George R., primary, Lee, J. Jack, primary, Lippman, Scott M., primary, Ang, K. Kian, primary, Mills, Gordon B., primary, Hong, Waun K., primary, Weinstein, John N., primary, Wistuba, Ignacio I., primary, Coombes, Kevin R., primary, Minna, John D., primary, and Heymach, John V., primary

Published
2023
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35. Supplemental Figure 4 from An Integrated Molecular Analysis of Lung Adenocarcinomas Identifies Potential Therapeutic Targets among TTF1-Negative Tumors, Including DNA Repair Proteins and Nrf2

Author

Cardnell, Robert J.G., primary, Behrens, Carmen, primary, Diao, Lixia, primary, Fan, YouHong, primary, Tang, Ximing, primary, Tong, Pan, primary, Minna, John D., primary, Mills, Gordon B., primary, Heymach, John V., primary, Wistuba, Ignacio I., primary, Wang, Jing, primary, and Byers, Lauren A., primary

Published
2023
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36. Supplementary Figure 1 from An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

Author

Byers, Lauren Averett, primary, Diao, Lixia, primary, Wang, Jing, primary, Saintigny, Pierre, primary, Girard, Luc, primary, Peyton, Michael, primary, Shen, Li, primary, Fan, Youhong, primary, Giri, Uma, primary, Tumula, Praveen K., primary, Nilsson, Monique B., primary, Gudikote, Jayanthi, primary, Tran, Hai, primary, Cardnell, Robert J.G., primary, Bearss, David J., primary, Warner, Steven L., primary, Foulks, Jason M., primary, Kanner, Steven B., primary, Gandhi, Varsha, primary, Krett, Nancy, primary, Rosen, Steven T., primary, Kim, Edward S., primary, Herbst, Roy S., primary, Blumenschein, George R., primary, Lee, J. Jack, primary, Lippman, Scott M., primary, Ang, K. Kian, primary, Mills, Gordon B., primary, Hong, Waun K., primary, Weinstein, John N., primary, Wistuba, Ignacio I., primary, Coombes, Kevin R., primary, Minna, John D., primary, and Heymach, John V., primary

Published
2023
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37. Supplemental Figure 2 from An Integrated Molecular Analysis of Lung Adenocarcinomas Identifies Potential Therapeutic Targets among TTF1-Negative Tumors, Including DNA Repair Proteins and Nrf2

Author

Cardnell, Robert J.G., primary, Behrens, Carmen, primary, Diao, Lixia, primary, Fan, YouHong, primary, Tang, Ximing, primary, Tong, Pan, primary, Minna, John D., primary, Mills, Gordon B., primary, Heymach, John V., primary, Wistuba, Ignacio I., primary, Wang, Jing, primary, and Byers, Lauren A., primary

Published
2023
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38. Supplemental Tables 1 & 2 from An Integrated Molecular Analysis of Lung Adenocarcinomas Identifies Potential Therapeutic Targets among TTF1-Negative Tumors, Including DNA Repair Proteins and Nrf2

Author

Cardnell, Robert J.G., primary, Behrens, Carmen, primary, Diao, Lixia, primary, Fan, YouHong, primary, Tang, Ximing, primary, Tong, Pan, primary, Minna, John D., primary, Mills, Gordon B., primary, Heymach, John V., primary, Wistuba, Ignacio I., primary, Wang, Jing, primary, and Byers, Lauren A., primary

Published
2023
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39. Supplementary Figure 2 from An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

Author

Byers, Lauren Averett, primary, Diao, Lixia, primary, Wang, Jing, primary, Saintigny, Pierre, primary, Girard, Luc, primary, Peyton, Michael, primary, Shen, Li, primary, Fan, Youhong, primary, Giri, Uma, primary, Tumula, Praveen K., primary, Nilsson, Monique B., primary, Gudikote, Jayanthi, primary, Tran, Hai, primary, Cardnell, Robert J.G., primary, Bearss, David J., primary, Warner, Steven L., primary, Foulks, Jason M., primary, Kanner, Steven B., primary, Gandhi, Varsha, primary, Krett, Nancy, primary, Rosen, Steven T., primary, Kim, Edward S., primary, Herbst, Roy S., primary, Blumenschein, George R., primary, Lee, J. Jack, primary, Lippman, Scott M., primary, Ang, K. Kian, primary, Mills, Gordon B., primary, Hong, Waun K., primary, Weinstein, John N., primary, Wistuba, Ignacio I., primary, Coombes, Kevin R., primary, Minna, John D., primary, and Heymach, John V., primary

Published
2023
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40. Supplementary Figure 6 from An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

Author

Byers, Lauren Averett, primary, Diao, Lixia, primary, Wang, Jing, primary, Saintigny, Pierre, primary, Girard, Luc, primary, Peyton, Michael, primary, Shen, Li, primary, Fan, Youhong, primary, Giri, Uma, primary, Tumula, Praveen K., primary, Nilsson, Monique B., primary, Gudikote, Jayanthi, primary, Tran, Hai, primary, Cardnell, Robert J.G., primary, Bearss, David J., primary, Warner, Steven L., primary, Foulks, Jason M., primary, Kanner, Steven B., primary, Gandhi, Varsha, primary, Krett, Nancy, primary, Rosen, Steven T., primary, Kim, Edward S., primary, Herbst, Roy S., primary, Blumenschein, George R., primary, Lee, J. Jack, primary, Lippman, Scott M., primary, Ang, K. Kian, primary, Mills, Gordon B., primary, Hong, Waun K., primary, Weinstein, John N., primary, Wistuba, Ignacio I., primary, Coombes, Kevin R., primary, Minna, John D., primary, and Heymach, John V., primary

Published
2023
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41. Supplemental Table 3 from An Integrated Molecular Analysis of Lung Adenocarcinomas Identifies Potential Therapeutic Targets among TTF1-Negative Tumors, Including DNA Repair Proteins and Nrf2

Author

Cardnell, Robert J.G., primary, Behrens, Carmen, primary, Diao, Lixia, primary, Fan, YouHong, primary, Tang, Ximing, primary, Tong, Pan, primary, Minna, John D., primary, Mills, Gordon B., primary, Heymach, John V., primary, Wistuba, Ignacio I., primary, Wang, Jing, primary, and Byers, Lauren A., primary

Published
2023
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42. Supplemental Figure 1 from An Integrated Molecular Analysis of Lung Adenocarcinomas Identifies Potential Therapeutic Targets among TTF1-Negative Tumors, Including DNA Repair Proteins and Nrf2

Author

Cardnell, Robert J.G., primary, Behrens, Carmen, primary, Diao, Lixia, primary, Fan, YouHong, primary, Tang, Ximing, primary, Tong, Pan, primary, Minna, John D., primary, Mills, Gordon B., primary, Heymach, John V., primary, Wistuba, Ignacio I., primary, Wang, Jing, primary, and Byers, Lauren A., primary

Published
2023
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43. Supplementary Table 3 from An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

Author

Byers, Lauren Averett, primary, Diao, Lixia, primary, Wang, Jing, primary, Saintigny, Pierre, primary, Girard, Luc, primary, Peyton, Michael, primary, Shen, Li, primary, Fan, Youhong, primary, Giri, Uma, primary, Tumula, Praveen K., primary, Nilsson, Monique B., primary, Gudikote, Jayanthi, primary, Tran, Hai, primary, Cardnell, Robert J.G., primary, Bearss, David J., primary, Warner, Steven L., primary, Foulks, Jason M., primary, Kanner, Steven B., primary, Gandhi, Varsha, primary, Krett, Nancy, primary, Rosen, Steven T., primary, Kim, Edward S., primary, Herbst, Roy S., primary, Blumenschein, George R., primary, Lee, J. Jack, primary, Lippman, Scott M., primary, Ang, K. Kian, primary, Mills, Gordon B., primary, Hong, Waun K., primary, Weinstein, John N., primary, Wistuba, Ignacio I., primary, Coombes, Kevin R., primary, Minna, John D., primary, and Heymach, John V., primary

Published
2023
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44. CRL4SlDDI3 regulates cell proliferation and organ size via targeting H3K9 methyltransferase SlDDI4 for degradation in tomato

Author

Miao, Min, primary, Tang, Xiaofeng, additional, Gao, Lanyang, additional, Gao, Jieyu, additional, Wang, Hongtao, additional, Wang, Songhu, additional, Zhu, Yunye, additional, Niu, Xiangli, additional, Fan, Youhong, additional, Chen, Yao, additional, Li, Yuxiang, additional, Wang, Anquan, additional, Cao, Shuqing, additional, Fei, Zhangjun, additional, Giovannoni, James, additional, Xiao, Fangming, additional, and Liu, Yongsheng, additional

Published
2023
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45. The Design and Repair of the Modern "Chinese Style Roof": Architectural Heritage: A Case Study on the Office Building of Zhongshan Botanical Garden in Nanjing.

Author

YANG Ling, CHUN Qing, LIN Yijie, and FAN Youhong

Subjects
BOTANICAL gardens, WESTERN civilization, HIGH technology, REPAIRING, COGNITIVE computing
Abstract

In the practice of modern local architectural construction, how to build traditional "Chinese style roof" through Western advanced technology became a hot issue. Due to the collision between Chinese and Western culture and technology, some common damage problems emerged in the form-oriented "Chinese style roof" architectural heritage. This paper looks at the office building of Zhongshan Botanical Garden in Nanjing built in the 1950s, points out the collision between the translation of typical forms and the integration of Chinese and Western construction technologies from the perspective of current damage analysis, and puts forward the way of repair and reinforcement through "minimum intervention", which will provide a more profound cognitive basis and reference direction for the conservation of "Chinese style roof" architectural heritage. [ABSTRACT FROM AUTHOR]

Published
2023
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46. Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with β-blockers

Author

Nilsson, Monique B., Sun, Huiying, Diao, Lixia, Tong, Pan, Liu, Diane, Li, Lerong, Fan, Youhong, Poteete, Alissa, Lim, Seung-Oe, Howells, Kathryn, Haddad, Vincent, Gomez, Daniel, Tran, Hai, Pena, Guillermo Armaiz, Sequist, Lecia V., Yang, James C., Wang, Jing, Kim, Edward S., Herbst, Roy, Lee, J. Jack, Hong, Waun Ki, Wistuba, Ignacio, Hung, Mien-Chie, Sood, Anil K., and Heymach, John V.

Published
2017
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48. Enhanced Vulnerability of LKB1-Deficient NSCLC to Disruption of ATP Pools and Redox Homeostasis by 8-Cl-Ado

Author

Galan-Cobo, Ana, primary, Stellrecht, Christine M., additional, Yilmaz, Emrullah, additional, Yang, Chao, additional, Qian, Yu, additional, Qu, Xiao, additional, Akhter, Ishita, additional, Ayres, Mary L., additional, Fan, Youhong, additional, Tong, Pan, additional, Diao, Lixia, additional, Ding, Jie, additional, Giri, Uma, additional, Gudikote, Jayanthi, additional, Nilsson, Monique, additional, Wierda, William G., additional, Wang, Jing, additional, Skoulidis, Ferdinandos, additional, Minna, John D., additional, Gandhi, Varsha, additional, and Heymach, John V., additional

Published
2021
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49. SARS-CoV-2 infection induces EMT-like molecular changes, including ZEB1-mediated repression of the viral receptor ACE2, in lung cancer models

Author

Stewart, C. Allison, Gay, Carl M., Ramkumar, Kavya, Cargill, Kasey R., Cardnell, Robert J., Nilsson, Monique B., Heeke, Simon, Park, Elizabeth M., Kundu, Samrat T., Diao, Lixia, Wang, Qi, Shen, Li, Xi, Yuanxin, Maria Della Corte, Carminia, Fan, Youhong, Kundu, Kiran, Pickering, Curtis R., Johnson, Faye M., Zhang, Jianjun, Kadara, Humam, Minna, John D., Gibbons, Don L., Wang, Jing, Heymach, John V., and Byers, Lauren Averett

Subjects
hormones, hormone substitutes, and hormone antagonists, Article
Abstract

COVID-19 is an infectious disease caused by SARS-CoV-2, which enters host cells via the cell surface proteins ACE2 and TMPRSS2. Using normal and malignant models and tissues from the aerodigestive and respiratory tracts, we investigated the expression and regulation of ACE2 and TMPRSS2. We find that ACE2 expression is restricted to a select population of highly epithelial cells and is repressed by ZEB1, in concert with ZEB1’s established role in promoting epithelial to mesenchymal transition (EMT). Notably, infection of lung cancer cells with SARS-CoV-2 induces metabolic and transcriptional changes consistent with EMT, including upregulation of ZEB1 and AXL, thereby downregulating ACE2 post-infection. This suggests a novel model of SARS-CoV-2 pathogenesis in which infected cells shift toward an increasingly mesenchymal state and lose ACE2 expression, along with its acute respiratory distress syndrome-protective effect, in a ZEB1-dependent manner. AXL-inhibition and ZEB1-reduction, as with bemcentinib, offers a potential strategy to reverse this effect.

Published
2020

50. A YAP/FOXM1 axis mediates EMT-associated EGFR inhibitor resistance and increased expression of spindle assembly checkpoint components

Author

Nilsson, Monique B., primary, Sun, Huiying, additional, Robichaux, Jacqulyne, additional, Pfeifer, Matthias, additional, McDermott, Ultan, additional, Travers, Jon, additional, Diao, Lixia, additional, Xi, Yuanxin, additional, Tong, Pan, additional, Shen, Li, additional, Hofstad, Mia, additional, Kawakami, Masanori, additional, Le, Xiuning, additional, Liu, Xi, additional, Fan, Youhong, additional, Poteete, Alissa, additional, Hu, Limei, additional, Negrao, Marcelo V., additional, Tran, Hai, additional, Dmitrovsky, Ethan, additional, Peng, David, additional, Gibbons, Don L., additional, Wang, Jing, additional, and Heymach, John V., additional

Published
2020
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