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C14H26N2O14Mg, triclinic, P1‾$\overline{1}$ (no. 2), a = 7.0646(2) Å, b = 8.5008(2) Å, c = 17.2402(2) Å, α = 86.230(2)°, β = 81.415(2)°, γ = 82.768(2)°, V = 1014.45(4) Å3, Z = 2, Rgt(F) = 0.0340, wRref(F2) = 0.0904, T = 216(40) K.

A new trinuclear Zn (II) complex, [Zn3(L1)4(L2)2(CH3COO)2] (1) (HL1 = 6-phenylpyridine-2-carboxylic acid, L2 = bis(4-pyridyl)amine) has been synthesized by 6-phenylpyridine-2-carboxylic acid, NaOH, bis(4-pyridyl)amine and Zn(CH3COO)2•2H2O. The complex 1 has also been structural characterized by elemental analysis and single crystal X-ray diffraction. The results reveals that complex 1 is made up of three Zn(II) ions, four L1 ligands, two L2 ligands and two CH3COO- anions. In 1, both Zn1 ion and Zn1a ion are five-coordinated with two O atoms from two different L1 ligands, two N atoms from two different L1 ligands, and one N atoms from bis(4-pyridyl)amine ligand, respectively, and forms a distorted trigonal biyramid geometry. And Zn2 ion is four-coordinated with two O atoms from two different CH3COO− anions and two N atoms from two different L2 ligands, forming a distorted tetrahedral geometry. Complex 1 displays a 3D network structure by the intermolecular N−H···O hydrogen bonds. The catalytic performance for oxidation of benzyl alcohol with O2 was studied under mild reaction conditions using complex 1 as catalyst. The results demonstrated that the catalysts were very active, and the yield of benzaldehyde was 50.8% at 90 °C with THF as solvent under 0.5 MPa O2 within 3 h. Copyright © 2022 by Authors, Published by BCREC Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).

In ethanol-water (v:v = 1:1), a new Ni(II) complex, [Ni(L)2(H2O)2] (1) (HL = 6-phenylpyridine-2-carboxylic acid) was synthesized using 6-phenylpyridine-2-carboxylic acid, NaOH and Ni(CH3COO)2.4H2O. The structure of complex 1 has been determined by elemental analysis and single crystal X-ray diffraction. The single crystal analysis shows that complex 1 contains one Ni(II) ion, two L ligands and two coordinated water molecules. In 1, the Ni(II) ion is six-coordinated to two O atoms and two N atoms from L ligands and two O atoms from coordinated water molecules, respectively, which form a distorted octahedral coordination geometry. The whole unit of complex 1 is interconnected to each other through intermolecular N−H•••O hydrogen bonds involving oxygen atom of coordinated water molecule and the oxygen atoms of L ligand to form 1D molecular architecture. The catalytic activity of complex 1 for oxidation of benzyl alcohol with O2 was investigated. The complex 1 shows good catalytic performance for the oxidation of benzyl alcohol, the benzyl alcohol conversion, benzaldehyde selectivity, and benzaldehyde yield were 49.1%, 92.0%, and 45.2%, respectively, at 90 °C under 0.7 Mpa O2 for 2 h. Moreover, complex 1 could be recovered easily by centrifugation and used repetitively for at least four times. Copyright © 2022 by Authors, Published by BCREC Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).

A new six-coordinated Mn(II) coordination polymer, [Mn(L1)(L2)2]n (L1 = 2-aminopyrimidine, HL2 = 3-bromo-2-hydroxybenzaldehyde) was synthesized by 3-bromo-2-hydroxybenzaldehyde, NaOH, 2-aminopyrimidine and manganese(II) acetate dihydrate. The Mn(II) coordination polymer was structural characterized by elemental analysis and single crystal X-ray diffraction. The results show that each Mn(II) ion is six-coordinated with two phenolic hydroxyl O atoms from two 3-bromo-2-hydroxybenzaldehyde ligands (O1 and O4), two formyl group O atoms from two 3-bromo-2-hydroxybenzaldehyde ligands (O2 and O3), and two N atoms from two 2-aminopyrimidine molecules (N1A and N2), and forms a distorted octahedral coordination geometry. The Mn(II) coordination polymer displays a 1D chained structure by the bridge effect of 2-aminopyrimidine N atoms. The catalytic activities of Mn(II) coordination polymer and Pd@Mn(II) coordination polymer for hydrogenation of 1,3-butadiene have been investigated. The Pd@Mn(II) coordination polymer catalyst shows the good catalytic activity and selectivity in the hydrogenation of 1,3-butadiene. The 1,3-butadiene conversion is 61.3% at 70 °C, and the selectivity to total butene is close to 100%. Copyright © 2021 by Authors, Published by BCREC Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).

Background Tuberculous meningitis (TBM) is a common central nervous system (CNS) infectious disease,and is a serious threat to people's health. Due to its diverse clinical manifestations, especially atypical in infants and young children, it is easy to be misdiagnosed and can lead to high disablility rate and mortality rate. At present, cerebrospinal fluid (CSF) cytology still plays an important role in the etiological diagnosis of CNS infectious diseases. Based on the observation of CSF cytological changes of children with TBM, this study is to further understand the performance and evolution characteristics of this disease, so as to improve the ability of early diagnosis and judgment on the treatment effect. Methods Fresh CSF was collected to make smears by using cytological slide centrifugation, and apply May-Grunwald-Giemsa (MGG) staining for morphological classification. Results CSF cytology of all patients were abnormal. The average leukocyte count of children with TBM was (310.19 ± 156.26) × 106/L, and was significantly different from that of children with purulent meningitis (P = 0.000). Lymphocyte proportion of TBM group was (66.56 ± 14.08)% , and there were significant differences among different groups (P = 0.037, 0.000). Compared to children with purulent meningitis, higher proportion of monocytes (P = 0.000, 0.020) and plasma cells (P = 0.001, 0.004) were found in children with TBM and viral meningitis. The positive detection rate of plasma cells in children with TBM was higher than that in children with purulent meningitis (P = 0.001). Conclusion The CSF cytology changing characteristics of children with TBM are revealed. In the beginning the lymphocyte proportion is dominant in CSF cytology, and then different extents of mixed cellular response appear as disease develops. For children with effective treatment, the proportion of neutrophils decreases rapidly and turns to lymphocyte reaction gradually, with monocytes and plasma cells, lasting for a long time. Long-term mixed cellular response will happen in children with ineffective treatment. All in all, the CSF cytology changing characteristics are significant in clinical diagnosis and differential diagnosis of TBM in children.

Objective To analyze the clinical and cerebrospinal fluid (CSF) cytological features of patients with tuberculous meningitis (TBM), to improve early diagnostic accuracy and treatment of TBM. Methods Clinical presentations, etiology and biochemical and cytological features of CSF were analyzed retrospectively among 60 adult cases with TBM hospitalized at Neurology Department of General Hospital of Ningxia Medical University from January 2005 to May 2011. Results Most patients (58/60, 96.67%) had fever and headache at onset. In some patients, disturbance of consciousness (9/60, 15.00%), seizure (5/60, 8.33%) occurred in 1 week and focal neurological signs developed during the course. Forty⁃four patients (73.33%) had pulmonary tuberculosis history. In CSF examination, acid⁃fast bacillus positive was found in 8 patients. Positive acid ⁃ fast myobacterium tuberculous culture was detected in 5 patients and positive myobacterium tuberculosis DNA were seen in 5 patients. The main changes of CSF were intracranial hypertension, increase of protein, and decrease of glucose. CSF presented mixed cellular response with predominace in the increasing of leucocytes. During early stage the mean percentage of neutrophil in CSF was less than 40%. After short term (as long as 2 months) of regular antituberculotic therapy no significant changes in total cell count and the proportion of neutrophils were seen. In 60 patients, 44 patients were ameliorated, 11 were not healed or were discharged or transferred to other hospital and 5 were dead. Prognosis of patients treated within 3 weeks after onsets was superiorly to those treated at more than 3 weeks after onset. Conclusion There are no specific clinical features in TBM and it is hard to perform early diagnosis for TBM, particularly, existing of low efficiency in pathogenic detection, but pulmonary tuberculosis is of accessary value to diagnose TBM. Whereas mixed cellular response may complementarily provide the diagnosis of TBM in early stage. Cytologic changes of CSF can be very slow even after therapy. Therefore persistent mixed cellular response in CSF cannot exclude TBM. The time of treatment will determine the therapeutic effectiveness in a great degree. DOI：10.3969/j.issn.1672⁃6731.2012.02.021

In the title compound, C13H14N4O2S, the dihedral angle between the aromatic rings is 55.42 (14)°. In the crystal structure, an N—H...O hydrogen bond leads to chains of molecules along [001].

In the title compound, C17H21N3O3S, the dihedral angle between the aromatic ring planes is 84.2 (2)°. The pendant ethyl groups of the –N(C2H5)2 group are disordered over two sets of positions in a 0.84 (2):0.16 (2) ratio. The molecular conformation is stabilized by an intramolecular O—H...N hydrogen bond, and intermolecular N—H...O bonds lead to [010] chains in the crystal structure.

In the cation of the title compound, [Co(H2O)6](C13H10NO4S)2, the Co atom lies on a centre of symmetry and its coordination geometry is octahedral. The crystal structure is stabilized by water–anion O—H...O hydrogen bonds. An intramolecular O—H...N hydrogen bond occurs in the anion.

There are two molecules in the asymmetric unit of the title compound, C15H16N2O4S, both of which are stabilized by an intramolecular O—H...N hydrogen bond. Intermolecular N—H...O hydrogen bonds lead to [101] chains of molecules in the crystal structure.

In the title fused-ring compound, C12H13NO3, the two five-membered C3NO rings both approximate to envelope conformations with C atoms in the flap positions. The OH group of the pendant CH2OH unit is disordered over two positions in a 0.528 (5):0.472 (5) ratio. One of the OH groups participates in an O—H...N hydrogen bond, generating centrosymmetric dimers in the crystal structure.

C14H26N2O14Mg, triclinic, P 1 ‾ (no. 2), a = 7.0646(2) Å, b = 8.5008(2) Å, c = 17.2402(2) Å, α = 86.230(2)°, β = 81.415(2)°, γ = 82.768(2)°, V = 1014.45(4) Å3, Z = 2, Rgt(F) = 0.0340, wRref(F2) = 0.0904, T = 216(40) K. [ABSTRACT FROM AUTHOR]