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4. Association between sleep quality and polymorphisms of the genes COMT, HTR2A and FKBP5 in individuals with and without dentofacial deformity.

Author

Barriga Flores, Elvira Katherine, Fanderuff, Marina, Miranda dos Santos, Katheleen, Nascimento Meger, Michelle, João da Costa, Delson, Mueler Storrer, Carmen Lucia, and Scariot, Rafaela

Subjects
SLEEP quality, SLEEP interruptions, CATECHOL-O-methyltransferase gene, ORAL mucosa, GENETIC polymorphisms
Abstract

Sleep is a fundamental biological function, and any disturbances can lead to alterations in an individual's physical, occupational, cognitive, and social functioning. Aim: This study aimed to evaluate the quality of sleep and its association with factors such as age, sex, facial profile, and genetic polymorphisms in individuals who underwent dental treatment. Methods: The study comprised a total of 227 individuals. The "Sleep Assessment Questionnaire" was utilized to evaluate sleep quality. For the genetic assessment, oral mucosa cells were collected and markers from the COMT (rs174675, rs165656), HTR2A (rs4941573, rs6313), and FKBP5 (rs1360780, rs3800373) genes were selected for real-time PCR analysis. The data were subjected to statistical analysis with a significance level of 0.05. Results: The results showed that women had a poorer perception of sleep quality (p<0.05). There was a significant association between sleep quality and facial profile (p<0.05). Individuals with facial profiles I and II had a poorer perception of sleep quality in general and in the domains of non-restorative sleep, sleep time disturbance, and restlessness. Individuals with facial profile II had a poorer perception of sleep apnea than those with profile III (p=0.034). There was a significant association between the COMT rs174675 polymorphism and restlessness (p=0.035). Conclusion: The poorest perception of sleep quality was associated with women and individuals with facial profiles I and II. The poorest perception of restlessness was associated with COMT rs174675 polymorphism. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Prevalence of clinical signs and diagnosis of temporomandibular disorders in adults with intellectual disability.

Author

Mendes PUPO, Yasmine, da Silva REIS, Giselle Emilãine, Preizner DEZANETTI, Jullyana Mayara, FANDERUFF, Marina, Louise SCHOSSLER, Thábata, Rasmussen PETTERLE, Ricardo, Alves CAVALHEIRO, Amanda Kerin, BONOTTO, Daniel, Carvalho TORRES-PEREIRA, Cassius, and Brenner HILGENBERG-SYDNEY, Priscila

Subjects
JOINT pain, MANDIBULAR joint, INTELLECTUAL disabilities, OROFACIAL pain, GENDER differences (Sociology)
Abstract

Copyright of Universidade Estadual Paulista. Revista de Odontologia is the property of Universidade Estadual Paulista. Revista de Odontologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2024
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6. Atypical Mandibular Angle Fracture

Author

Junior, Wanderley da Silva Félix, Fanderuff, Marina, Reis, Thiago Vinicius Rodrigues, Rebellato, Nelson Luis Barbosa, Scariot, Rafaela, and Klüppel, Leandro Eduardo

Published
2019
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8. RESECTION OF MULTICYSTIC AMELOBLASTOMA: CASE REPORT

Author

Fanderuff, Marina, primary, Cordeiro, Lidiana Dos Santos, additional, Sebastiani, Aline Monise, additional, Rebellato, Nelson Luis Barbosa, additional, Kluppel, Leandro Eduardo, additional, Scariot, Rafaela, additional, and Da Costa, Delson João, additional

Published
2022
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10. Total Mandibular Subapical Alveolar Osteotomy to Correct Class II Division I Dentofacial Deformity

Author

Cavalcante, Rafael Correia, Bergamaschi, Isabela Polesi, Sebastiani, Aline Monise, Galina, Fabiano, Fanderuff, Marina, da Costa, Delson João, Rebellato, Nelson Luis Barbosa, Scariot, Rafaela, and Klüppel, Leandro Eduardo

Subjects
Article Subject
Abstract

Introduction. Class II division I malocclusions are the most common dentofacial deformities seen in clinical practice. Severe cases or cases in which growth has ceased may require full correction combining orthodontic and surgical treatment. We report a case of a total mandibular subapical alveolar osteotomy, performed to correct a class II division I dentofacial deformity. Case Report. A 19-year-old female patient was referred to the oral and maxillofacial surgery department at the Federal University of Paraná with chin aesthetic complaints as well as class II malocclusion. The proposed treatment was total mandibular subapical alveolar osteotomy, retaining the chin position and eliminating the need for genioplasty, since, although the patient presented with a class II dentofacial deformity, the chin was well positioned. Under general anesthesia, a “V-shaped” incision was conducted from the right retromolar region to the left retromolar region. A ring of cortical bone was removed around the mental foramen, with the aim to create a space around the mental nerve. Fixation was conducted with plates and screws of the 2.0 system. The patient on six-year follow-up showed osteotomy stability, a better overall occlusion, and outcome satisfaction.

Published
2018
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12. Total Mandibular Subapical Alveolar Osteotomy to Correct Class II Division I Dentofacial Deformity

Author

Correia Cavalcante, Rafael, Polesi Bergamaschi, Isabela, Monise Sebastiani, Aline, Galina, Fabiano, Fanderuff, Marina, João da Costa, Delson, Luis Barbosa Rebellato, Nelson, Scariot, Rafaela, and Eduardo Klüppel, Leandro

Abstract

Introduction. Class II division I malocclusions are the most common dentofacial deformities seen in clinical practice. Severe cases or cases in which growth has ceased may require full correction combining orthodontic and surgical treatment. We report a case of a total mandibular subapical alveolar osteotomy, performed to correct a class II division I dentofacial deformity. Case Report. A 19-year-old female patient was referred to the oral and maxillofacial surgery department at the Federal University of Paraná with chin aesthetic complaints as well as class II malocclusion. The proposed treatment was total mandibular subapical alveolar osteotomy, retaining the chin position and eliminating the need for genioplasty, since, although the patient presented with a class II dentofacial deformity, the chin was well positioned. Under general anesthesia, a “V-shaped” incision was conducted from the right retromolar region to the left retromolar region. A ring of cortical bone was removed around the mental foramen, with the aim to create a space around the mental nerve. Fixation was conducted with plates and screws of the 2.0 system. The patient on six-year follow-up showed osteotomy stability, a better overall occlusion, and outcome satisfaction.

Published
2018
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