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Your search keyword '"Fang, Dazhao"' showing total 18 results
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18 results on '"Fang, Dazhao"'

6. Dexmedetomidine Inhibits Gasdermin D-Induced Pyroptosis via the PI3K/AKT/GSK3β Pathway to Attenuate Neuroinflammation in Early Brain Injury After Subarachnoid Hemorrhage in Rats

Author

Wei, Boyang, primary, Liu, Wenchao, additional, Jin, Lei, additional, Guo, Shenquan, additional, Fan, Haiyan, additional, Jin, Fa, additional, Wei, Chengcong, additional, Fang, Dazhao, additional, Zhang, Xin, additional, Su, Shixing, additional, Duan, Chuanzhi, additional, and Li, Xifeng, additional

Published
2022
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8. Metformin Inhibits NLR Family Pyrin Domain Containing 3 (NLRP)-Relevant Neuroinflammation via an Adenosine-5′-Monophosphate-Activated Protein Kinase (AMPK)-Dependent Pathway to Alleviate Early Brain Injury After Subarachnoid Hemorrhage in Mice

Author

Jin, Lei, primary, Jin, Fa, additional, Guo, Shenquan, additional, Liu, Wenchao, additional, Wei, Boyang, additional, Fan, Haiyan, additional, Li, Guangxu, additional, Zhang, Xin, additional, Su, Shixing, additional, Li, Ran, additional, Fang, Dazhao, additional, Duan, Chuanzhi, additional, and Li, Xifeng, additional

Published
2022
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10. Resolvin D1 ameliorates Inflammation-Mediated Blood-Brain Barrier Disruption After Subarachnoid Hemorrhage in rats by Modulating A20 and NLRP3 Inflammasome

Author

Wei, Chengcong, primary, Guo, Shenquan, additional, Liu, Wenchao, additional, Jin, Fa, additional, Wei, Boyang, additional, Fan, Haiyan, additional, Su, Hengxian, additional, Liu, Jiahui, additional, Zhang, Nan, additional, Fang, Dazhao, additional, Li, Guangxu, additional, Shu, Shixing, additional, Li, Xifeng, additional, He, Xuying, additional, Zhang, Xin, additional, and Duan, Chuanzhi, additional

Published
2021
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15. Hyperbaric oxygen treatment and enteral nutrition support with glutamine relieves traumatic brain injury in the rats

Author

Fu, Xianhua, Zhu, Min, Sun, Xiaoyang, Fang, Dazhao, Wang, Weijie, Dong, Nan, Pang, Cong, Liu, Xiaoning, Chen, Fengli, and Ding, Lianshu

Subjects
nervous system, Original Article, nervous system diseases
Abstract

The abnormal metabolic processes following traumatic brain injury (TBI) have been proposed to contribute to secondary injuries after TBI. Therefore, enteral nutrition (EN) support for TBI patients has received more attention. This study aimed to evaluate the complimentary effects of enteral nutrition with glutamine and hyperbaric oxygen (HBO) on the recovery of TBI. TBI model was established in SD rats, which were randomly divided into four groups: TBI, TBI + HBO, TBI + GLN, and TBI + HBO + GLN. Neuronal apoptosis in penumbra area was detected by TUNEL. Serum prealbumin level was detected by ELISA. Motor function was evaluated by beam-balance test. We found that the body weight of the rats had no significant differences in different groups before and after injury. Among the four groups, beam-balance test score was the lowest, serum prealbumin level was the highest, and neuronal apoptosis rate was the lowest in TBI + HBO + GLN group on day 3 and 7 after TBI. In conclusion, our data suggest that hyperbaric oxygen combined with enteral nutrition support with glutamine is effective in reducing neuronal apoptosis, increasing serum prealbumin concentration and improving neurological function after TBI injury.

Published
2014

18. Hyperbaric oxygen treatment and enteral nutrition support with glutamine relieves traumatic brain injury in the rats.

Author

Fu X, Zhu M, Sun X, Fang D, Wang W, Dong N, Pang C, Liu X, Chen F, and Ding L

Abstract

The abnormal metabolic processes following traumatic brain injury (TBI) have been proposed to contribute to secondary injuries after TBI. Therefore, enteral nutrition (EN) support for TBI patients has received more attention. This study aimed to evaluate the complimentary effects of enteral nutrition with glutamine and hyperbaric oxygen (HBO) on the recovery of TBI. TBI model was established in SD rats, which were randomly divided into four groups: TBI, TBI + HBO, TBI + GLN, and TBI + HBO + GLN. Neuronal apoptosis in penumbra area was detected by TUNEL. Serum prealbumin level was detected by ELISA. Motor function was evaluated by beam-balance test. We found that the body weight of the rats had no significant differences in different groups before and after injury. Among the four groups, beam-balance test score was the lowest, serum prealbumin level was the highest, and neuronal apoptosis rate was the lowest in TBI + HBO + GLN group on day 3 and 7 after TBI. In conclusion, our data suggest that hyperbaric oxygen combined with enteral nutrition support with glutamine is effective in reducing neuronal apoptosis, increasing serum prealbumin concentration and improving neurological function after TBI injury.

Published
2014

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