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Your search keyword '"Fang, Zhizheng"' showing total 21 results
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21 results on '"Fang, Zhizheng"'

8. PF-D-Trimer, a broadly protective SARS-CoV-2 subunit vaccine: immunogenicity and application

Author

Zhang, Zhihao, primary, Zhou, Jinhu, additional, Ni, Peng, additional, Hu, Bing, additional, Deng, Shuang, additional, Xiao, Qian, additional, He, Qian, additional, Li, Gai, additional, Xia, Yan, additional, Liu, Mei, additional, Wang, Cong, additional, Fang, Zhizheng, additional, Xia, Nan, additional, Zhang, Zhe-Rui, additional, Zhang, Bo, additional, Cai, Kun, additional, Jolicoeur, Normand, additional, Xu, Yan, additional, and Liu, Binlei, additional

Published
2022
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9. Development and application of an uncapped mRNA platform

Author

Liu, Biao, primary, Ni, Peng, additional, Cai, Linkang, additional, Shi, Xiaotai, additional, Ji, Shuaijie, additional, Ke, Zonghuang, additional, Zhang, Siqi, additional, Hu, Bing, additional, Yang, Binfeng, additional, Xu, Yiyan, additional, Long, Wei, additional, Fang, Zhizheng, additional, Hu, Han, additional, Wang, Yang, additional, Zhang, Wen, additional, Geng, Hui, additional, Xu, Yan., additional, Zheng, Xiaodi, additional, Wang, Zhong, additional, Zhang, Baoqian, additional, Pan, Kai, additional, Zhou, Kangping, additional, Cui, Yanfang, additional, Wang, Hanming, additional, and Liu, Binlei, additional

Published
2022
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11. Additional file 1 of A novel cocktail therapy based on quintuplet combination of oncolytic herpes simplex virus-2 vectors armed with interleukin-12, interleukin-15, GM-CSF, PD1v, and IL-7 × CCL19 results in enhanced antitumor efficacy

Author

Hu, Han, Zhang, Siqi, Cai, Linkang, Duan, Haixiao, Li, Yuying, Yang, Junhan, Wang, Yang, Liu, Biao, Dong, Shuang, Fang, Zhizheng, and Liu, Binlei

Abstract

Additional file 1: Fig. S1. Histopathological analysis of murine organ tissues by hematoxylin and eosin (H&E) staining.

Published
2022
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17. Preclinical Safety Evaluation of Oncolytic Herpes Simplex Virus Type 2

Author

Wang, Yang, primary, Zhou, Xiaobing, additional, Wu, Zhen, additional, Hu, Han, additional, Jin, Jing, additional, Hu, Yanping, additional, Dong, Yuting, additional, Zou, Jianwen, additional, Mao, Zeyong, additional, Shi, Xiaotai, additional, Huo, Yan, additional, Lyu, Jianjun, additional, Fang, Zhizheng, additional, Zhang, Wen, additional, Zhu, Yujie, additional, Li, Bo, additional, and Liu, Binlei, additional

Published
2019
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18. Stability and anti-tumor effect of oncolytic herpes simplex virus type 2

Author

Wang, Yang, primary, Jin, Jing, additional, Wu, Zhen, additional, Hu, Sheng, additional, Hu, Han, additional, Ning, Zhifeng, additional, Li, Yanfei, additional, Dong, Yuting, additional, Zou, Jianwen, additional, Mao, Zeyong, additional, Shi, Xiaotai, additional, Zheng, Huajun, additional, Dong, Shuang, additional, Liu, Fuxing, additional, Fang, Zhizheng, additional, Wu, Jiliang, additional, and Liu, Binlei, additional

Published
2018
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21. PiggyBac-modified CD19-expressing 4T1 cell line for the evaluation of CAR construct.

Author

Hu H, Wang R, Zhang Z, Duan H, Wang Y, Jin J, Chen Y, Wu Z, Fang Z, and Liu B

Abstract

Reliable and stable target cell lines are required for evaluating the efficiency and studying the mechanism of chimeric antigen receptor T (CAR-T) immunotherapy both in vitro and in vivo . Jurkat cells can be used as an alternative for human primary lymphocytes to evaluate the constructs and function of the "CAR". This study established a murine 4T1-CD19 cell line that stably expressed a cd19 gene. The 4T1-CD19 cells had similar growth kinetics to its parent cell 4T1. The protein CD19 expression of the 4T1-CD19 was detected by reverse transcription-polymerase chain reaction (RT-PCR) and western blot. The second-generation CAR was constructed and transfected into Jurkat cells. The expression of CAR protein was analyzed by flow cytometry and western blot. Finally, the interaction between the CAR and CD19 was confirmed by the upregulation of the IL-2 mRNA level of Jurkat-CAR stimulated by 4T1-CD19. Therefore, the 4T1-CD19 cell line and Jurkat-CAR have been successfully established, and may be used to access the function of various CAR constructs both in vitro and in vivo ., Competing Interests: None., (IJCEP Copyright © 2019.)

Published
2019

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