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Objectives This study aimed to evaluate the effect of labiopalatal inclination of maxillary right central incisor on palatal bone width using cone-beam computed tomography (CBCT). Methods The angle formed between the longitudinal axis of the right central incisor and the palatal plane was measured on 75 CBCT images, and classified into three groups of labially-inclined, lingually-inclined, and normal groups. The total palatal bone thickness in the apical region of the upper right central incisor was linearly measured perpendicular to the tooth axis on sagittal slices. The intraclass correlation coefficient, Kolmogorov-Smirnov test, one-way ANOVA, and Pearson’s and Spearman’s correlation coefficients were used for data analysis (alpha=0.05). Results A significant difference was noted among the groups in the total apical palatal bone thickness (P<0.05). The labially inclined group had significantly lower bone thickness than the other two groups (P=0.002, 95% CI: 5.5-7.38); however, this correlation was inverse (Pearson’s R=-0.58), which means that as the angle between the upper central incisor axis and the palatal plane increased, the bone thickness significantly decreased. No correlation was found between the palatal bone thickness (cancellous or cortical) and tooth inclination (P>0.05). Arch length was not correlated with any group either (P>0.05). Conclusion Labial inclination of upper central incisor causes the root apex to be closer to the palatal alveolar bone, resulting in less apical bone support in the palatal area. [ABSTRACT FROM AUTHOR]

The design, fabrication, and construction of the first steel bridge in the United States utilizing 100 ksi (690 MPa) high performance steel (HPS) are described. HPS box girders in conjunction with a structural system in which the girders would function as simple spans for dead loads and as continuous spans for live loads and superimposed dead loads was found economical even for spans shorter than 250 ft (76 m).

Background: Non-Syndromic Cleft Lip with or without cleft Palate (NSCL/P) is a common developmental disorder of the head and neck with a multifactorial etiology. The current study aimed to evaluate the potential association of PTCH1 (rs10512248) and RAD54B (rs12681366) polymorphisms with NSCL/P in the Northeast Iranian population., Methods: In the present study, blood samples were taken from 122 subjects with NSCL/P and 161 healthy controls. Polymerase Chain Reaction (PCR) followed by Restriction Fragment Length Polymorphism (RFLP) were used to conduct genotyping of single-nucleotide polymorphisms., Results: Although differences were observed between cases and controls in rs10512248 and rs12681366, our data did not support a significant association of these polymorphisms with NSCL/P in our population., Conclusion: Our findings suggest that polymorphisms of rs10512248 and rs12681366 may not be potential risk factors for NSCL/P in the Northeast Iranian population due to the multifactorial and multiethnicity characteristics of some genes., (Copyright© 2022 Avicenna Research Institute.)