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1. Improved Cosmological Constraints from New, Old and Combined Supernova Datasets

Author

Kowalski, M., Rubin, D., Aldering, G., Agostinho, R. J., Amadon, A., Amanullah, R., Balland, C., Barbary, K., Blanc, G., Challis, P. J., Conley, A., Connolly, N. V., Covarrubias, R., Dawson, K. S., Deustua, S. E., Ellis, R., Fabbro, S., Fadeyev, V., Fan, X., Farris, B., Folatelli, G., Frye, B. L., Garavini, G., Gates, E. L., Germany, L., Goldhaber, G., Goldman, B., Goobar, A., Groom, D. E., Haissinski, J., Hardin, D., Hook, I., Kent, S., Kim, A. G., Knop, R. A., Lidman, C., Linder, E. V., Mendez, J., Meyers, J., Miller, G. J., Moniez, M., Mourao, A. M., Newberg, H., Nobili, S., Nugent, P. E., Pain, R., Perdereau, O., Perlmutter, S., Phillips, M. M., Prasad, V., Quimby, R., Regnault, N., Rich, J., Rubenstein, E. P., Ruiz-Lapuente, P., Santos, F. D., Schaefer, B. E., Schommer, R. A., Smith, R. C., Soderberg, A. M., Spadafora, A. L., Strolger, L. -G., Strovink, M., Suntzeff, N. B., Suzuki, N., Thomas, R. C., Walton, N. A., Wang, L., Wood-Vasey, W. M., and Yun, J. L.

Subjects
Astrophysics
Abstract

We present a new compilation of Type Ia supernovae (SNe Ia), a new dataset of low-redshift nearby-Hubble-flow SNe and new analysis procedures to work with these heterogeneous compilations. This ``Union'' compilation of 414 SN Ia, which reduces to 307 SNe after selection cuts, includes the recent large samples of SNe Ia from the Supernova Legacy Survey and ESSENCE Survey, the older datasets, as well as the recently extended dataset of distant supernovae observed with HST. A single, consistent and blind analysis procedure is used for all the various SN Ia subsamples, and a new procedure is implemented that consistently weights the heterogeneous data sets and rejects outliers. We present the latest results from this Union compilation and discuss the cosmological constraints from this new compilation and its combination with other cosmological measurements (CMB and BAO). The constraint we obtain from supernovae on the dark energy density is $\Omega_\Lambda= 0.713^{+0.027}_{-0.029} (stat)}^{+0.036}_{-0.039} (sys)}$, for a flat, LCDM Universe. Assuming a constant equation of state parameter, $w$, the combined constraints from SNe, BAO and CMB give $w=-0.969^{+0.059}_{-0.063}(stat)^{+0.063}_{-0.066} (sys)$. While our results are consistent with a cosmological constant, we obtain only relatively weak constraints on a $w$ that varies with redshift. In particular, the current SN data do not yet significantly constrain $w$ at $z>1$. With the addition of our new nearby Hubble-flow SNe Ia, these resulting cosmological constraints are currently the tightest available., Comment: 49 pages, 17 figures; accepted for publication in Astrophysical Journal. For data tables, code for cosmological analysis and full-resolution figures, see http://supernova.lbl.gov/Union

Published
2008
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4. Improved Cosmological Constraints from New, Old, and Combined Supernova Data Sets

Author

Kowalski, M, Rubin, D, Aldering, G, Agostinho, RJ, Amadon, A, Amanullah, R, Balland, C, Barbary, K, Blanc, G, Challis, PJ, Conley, A, Connolly, NV, Covarrubias, R, Dawson, KS, Deustua, SE, Ellis, R, Fabbro, S, Fadeyev, V, Fan, X, Farris, B, Folatelli, G, Frye, BL, Garavini, G, Gates, EL, Germany, L, Goldhaber, G, Goldman, B, Goobar, A, Groom, DE, Haissinski, J, Hardin, D, Hook, I, Kent, S, Kim, AG, Knop, RA, Lidman, C, Linder, EV, Mendez, J, Meyers, J, Miller, GJ, Moniez, M, Mourão, AM, Newberg, H, Nobili, S, Nugent, PE, Pain, R, Perdereau, O, Perlmutter, S, Phillips, MM, Prasad, V, Quimby, R, Regnault, N, Rich, J, Rubenstein, EP, Ruiz-Lapuente, P, Santos, FD, Schaefer, BE, Schommer, RA, Smith, RC, Soderberg, AM, Spadafora, AL, Strolger, L-G, Strovink, M, Suntzeff, NB, Suzuki, N, Thomas, RC, Walton, NA, Wang, L, Wood-Vasey, WM, and Yun, JL

Subjects
Particle and High Energy Physics, Physical Sciences, cosmological parameters, cosmology: observations, supernovae: general, astro-ph, Astronomical and Space Sciences, Atomic, Molecular, Nuclear, Particle and Plasma Physics, Physical Chemistry (incl. Structural), Astronomy & Astrophysics, Astronomical sciences, Particle and high energy physics, Space sciences
Abstract

We present a new compilation of Type Ia supernovae (SNe Ia), a new data set of low-redshift nearby-Hubble-flow SNe, and new analysis procedures to work with these heterogeneous compilations. This "Union" compilation of 414 SNe Ia, which reduces to 307 SNe after selection cuts, includes the recent large samples of SNe Ia from the Supernova Legacy Survey and ESSENCE Survey, the older data sets, as well as the recently extended data set of distant supernovae observed with the Hubble Space Telescope (HST). A single, consistent, and blind analysis procedure is used for all the various SN Ia subsamples, and a new procedure is implemented that consistently weights the heterogeneous data sets and rejects outliers. We present the latest results from this Union compilation and discuss the cosmological constraints from this new compilation and its combination with other cosmological measurements (CMB and BAO). The constraint we obtain from supernovae on the dark energy density isΩΛ = 0.713-0.029+0.027(stat) -0.039+0.036(sys), for a flat, ACDM universe. Assuming a constant equation of state parameter, w, the combined constraints from SNe, BAO, and CMB give w = -0.969-0.063+0.059(stat) -0.066+0.063(sys). While our results are consistent with a cosmological constant, we obtain only relatively weak constraints on a w that varies with redshift. In particular, the current SN data do not yet significantly constrain w at z > 1. With the addition of our new nearby Hubble-flow SNe Ia, these resulting cosmological constraints are currently the tightest available. © 2008. The American Astronomical Society. All rights reserved.

Published
2008

6. Energy-Efficient Wireless Sensor Network with an Unequal Clustering Protocol Based on a Balanced Energy Method (EEUCB)

Author

Ahmed A. Jasim, Mohd Yamani Idna Idris, Saaidal Razalli Bin Azzuhri, Noor Riyadh Issa, Muhammad Towfiqur Rahman, and Muhammad Farris b Khyasudeen

Subjects
wireless sensor networks, unequal clustering, energy consumption, network lifetime, Chemical technology, TP1-1185
Abstract

A hot spot problem is a problem where cluster nodes near to the base station (BS) tend to drain their energy much faster than other nodes due to the need to perform more communication. Unequal clustering methods such as unequal clustering routing (UDCH) and energy-efficient fuzzy logic for unequal clustering (EEFUC) have been proposed to address this problem. However, these methods only concentrate on utilizing residual energy and the distance of sensor nodes to the base station, while limited attention is given to enhancing the data transmission process. Therefore, this paper proposes an energy-efficient unequal clustering scheme based on a balanced energy method (EEUCB) that utilizes minimum and maximum distance to reduce energy wastage. Apart from that, the proposed EEUCB also utilizes the maximum capacity of node energy and double cluster head technique with a sleep-awake mechanism. Furthermore, EEUCB has devised a clustering rotation strategy based on two sub-phases, namely intra- and inter-clustering techniques, that considers the average energy threshold, average distance threshold, and BS layering node. The performance of the proposed EEUCB protocol is then compared with various prior techniques. From the result, it can be observed that the proposed EEUCB protocol shows lifetime improvements of 57.75%, 19.63%, 14.7%, and 13.06% against low-energy adaptive clustering hierarchy (LEACH), factor-based LEACH FLEACH, EEFUC, and UDCH, respectively.

Published
2021
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8. Massive Black Hole Science with eLISA

Author

Barausse, E, Bellovary, J, Berti, E, Holley-Bockelmann, K, Farris, B, Sathyaprakash, B, Sesana, A, Barausse E., Bellovary J., Berti E., Holley-Bockelmann K., Farris B., Sathyaprakash B., Sesana A., Barausse, E, Bellovary, J, Berti, E, Holley-Bockelmann, K, Farris, B, Sathyaprakash, B, Sesana, A, Barausse E., Bellovary J., Berti E., Holley-Bockelmann K., Farris B., Sathyaprakash B., and Sesana A.

Abstract

The evolving Laser Interferometer Space Antenna (eLISA) will revolutionize our understanding of the formation and evolution of massive black holes (MBHs) along cosmic history, by probing massive black hole binaries (MBHBs) in the 103 - 107 Mo range out to redshift z ≳ 10. High signal-to-noise ratio detections of ∼ 10 - 100 MBHB coalescences per year will allow accurate measurements of the parameters of individual MBHBs (such as their masses, spins and luminosity distance), and a deep understanding of the underlying cosmic MBH parent population. This wealth of unprecedented information can lead to breakthroughs in many areas of physics, including astrophysics, cosmology and fundamental physics. We review the current status of the field, recent progress and future challenges.

Published
2015

9. Monitoring the quality of laboratories and the prevalence of resistance to antituberculosis drugs: Italy, 1998–2000

Author

Migliori, G. B., Fattorini, L., Vaccarino, R., Besozzi, G., Saltini, C., Orefici, G., Iona, E., Matteelli, A., Fiorentini, F., Codecasa, L. R., Casali, Lucio, Cassone, A., De Santis, A., Giorgio, V., Vinciguerra, P., Angarano, G., Petrozzi, L., Costa, D., Gozzellino, F., Perboni, A., Marchetti, D., Pascali, A., Falcone, F., Mariano, V., Rizza, F., Pretto, P., Turano, A., Carosi, G. P., Farris, A. G., Ligia, G. P., Orani, G., Farris, B., Foschi, C., Trucco, G., Aiolfi, S., Ceruti, T., Parpanesi, M., Calabro, S., Felisatti, G., Tortoli, E., Nutini, S., Montini, G., D'Ambrosio, V., Ceraminiello, A., Bernorio, S., Buono, L., Montesano, P., Vinci, E., Sabato, E., Gamba, S., Crepaldi, P., Magliano, E., Penati, V., Vaccarino, P., Astolfi, A., Bertoli, G., Rupianesi, F., Losi, M., Richeldi, L., Ferrara, Giovanni, Minuccio, E., Napolitano, G., Molinari, G. L., Saini, L., Garzone, A., Vertuccio, C., Marcias, S., Menozzi, M., Marone, P., Peona, V., Nascimbene, C., Pasi, A., Cascina, A., Monaco, A., Penza, O., Pasticci, Maria Bruna, Bistoni, F., Sposini, T., Colorizio, V., Confalonieri, M., Bottrighi, P., Macor, G., Moretti, G., Fatigante, R., Barbaro, A., Agati, G., Zaccara, F., Viola, S., Le Donne, R., Farinelli, G., Mancini, D., Ermeti, M., Longi, R., Tronci, M., Bisetti, A., Altieri, A., and Fadda, G.

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, Tuberculosis, Prevalence of resistance, Drug Resistance, Antitubercular Agents, Drug resistance, Proficiency testing, Drug, Immigrant, Susceptibility testing, Emigration and Immigration, Humans, Italy, Laboratories, Prevalence, Drug Resistance, Multiple, Bacterial, Tuberculosis, Multidrug-Resistant, Internal medicine, medicine, Ethambutol, business.industry, Public health, Isoniazid, Bacterial, Multidrug-Resistant, medicine.disease, Surgery, Streptomycin, business, Multiple, Rifampicin, medicine.drug
Abstract

In 1998 a network of 20 regional tuberculosis (TB) laboratories (the Italian Multicentre Study on Resistance to Antituberculosis drugs (SMIRA) network) was established in Italy to implement proficiency testing and to monitor the prevalence of drug resistance nationwide. The network managed 30% of all TB cases reported in Italy each year. The aim of the present report is to describe: 1) the accuracy of drug-susceptibility testing in the network; 2) the prevalence of drug resistance for the period 1998-2000. Data were collected from the network laboratories. Sensitivity to streptomycin and ethambutol increased from the first survey (1998-1999) to the second survey (2000) from 87.7 to 91.9%. Specificity, predictive values for resistance and susceptibility, efficiency and reproducibility were consistent in both surveys. In previously untreated cases, the prevalence of multidrug-resistance was the same in both surveys (1.2%), while a slight decrease from the first to the second survey was observed for monoresistance to rifampicin (from 0.8 to 0.4%) and isoniazid (from 2.9 to 2%). The significant association found between isoniazid resistance and immigration is a useful indicator for both clinicians managing individual tuberculosis cases and public health services planning control strategies.

Published
2003

10. Cost-comparison of different management policies for tuberculosis patients in Italy

Author

Migliori, G.B., Ambrosetti, M., Besozzi, G., Farris, B., Nutini, S., Saini, L., Casali, L., Nardini, S., Bugiani, M., Neri, M., and Raviglioni, M.C.

Abstract

Although in developing countries the treatment of tuberculosis (TB) cases is among the most cost-effective health interventions, few studies have evaluated the cost-effectiveness of TB control in low-prevalence countries. The aim of the present study was to carry out an economic analysis in Italy that takes into account both the perspective of the resource-allocating authority (i.e. the Ministry of Health) and the broader social perspective, including a cost description based on current outcomes applied to a representative sample of TB patients nationwide (admission and directly observed treatment (DOT) during the initial intensive phase of treatment); a cost-comparison analysis of two alternative programmes: current policy based on available data (scenario 1) and an hypothetical policy oriented more towards outpatient care (scenario 2) (both scenarios included the option of including or not including DOT outside hospital admission, and incentives) were compared in terms of cost per case treated successfully. Indirect costs (such as loss of productivity) were included in considerations of the broader social perspective. The study was designed as a prospective monitoring activity based on the supervised collection of forms from a representative sample of Italian TB units. Individual data were collected and analysed to obtain a complete economic profile of the patients enrolled and to evaluate the effectiveness of the intervention. A separate analysis was done for each scenario to determine the end-point at different levels of cure rate (50-90%). The mean length of treatment was 6.6 months (i.e. patients hospitalized during the intensive phase; length of stay was significantly higher in smear-positive patients and in human immunodeficiency virus (HIV) seropositive patients). Roughly six direct smear and culture examinations were performed during hospital admission and three during ambulatory treatment. The cost of a single bed day was US$ 186.90, whereas that of a single outpatient visit ranged, according to the different options, from US$ 2.50 to US$ 11. Scenario 2 was consistently less costly than scenario 1. The cost per case cured for smear-positive cases was US$ 16 703 in scenario 1 and US$ 5946 in scenario 2. The difference in cost between the cheapest option (no DOT) and the more expensive option (DOT, additional staff, incentives) ranged from US$ 1407 (scenario 1, smear-negative and extrapulmonary cases) to US$ 1814 (scenario 2, smear-positive cases). The additional cost to society including indirect costs ranged from US$ 1800 to US$ 4200. The possible savings at the national level were in the order of US$ 50 million per year. In conclusion, cost-comparison analysis showed that a relatively minor change in policy can result in significant savings and that the adoption of DOT will represent a relatively modest economic burden, although the real gain in effectiveness resulting from DOT in Italy requires further evaluation., Introduction The competition of health programmes for limited economic resources within national health systems has spawned an abundance of studies on economic evaluation in health care. Economic evaluation is the [...]

Published
1999

11. Surveillance of anti-tuberculosis drug resistance: Results of the 1998/1999 proficiency testing in Italy

Author

Migliori GB, Ambrosetti M, Fattorini L, Penati V, Vaccarino P, Besozzi G, Ortona L, Saltini C, Orefici G, Moro ML, Iona E, Cassone A, De Santis A, Giorgio V, Vinciguerra P, Angarano G, Petrozzi L, Costa D, Gozzellino F, Perboni A, Marchetti D, Pascali A, Falcone F, Mariano V, Rizza F, Pretto P, Turano A, Matteelli A, Carosi GP, Tedoldi S, Pinsi G, Farris AG, Ligia GP, Orani G, Farris B, Foschi C, Trucco G, Aiolfi S, Ceruti T, Parpanesi M, Calabro S, Felisatti G, Tortoli E, Nutini S, Montini G, Fiorentini F, D'Ambrosio V, Ceraminiello A, Bernorio S, Buono L, Montesano P, Vinci E, Sabato E, Gamba S, Crepaldi P, Bertoli G, Rupianesi F, Losi M, Richeldi L, Ferrara G, Muccio E, Napolitano G, Molinari GL, Saini L, Garzone A, Vertuccio C, Marcias, Menozzi, Marone P, Peona, Nascimbene, Pasi, Cascina, Casali, Monaco, Penza, Pasticci, M.B., Bistoni, Sposini, Colorizio, Confalonieri M, Bottrighi P, Orsi, Schiavi, Macor, Moretti, Fatigante, Barbaro, Agati, Zacarra, Viola, Le Donne, Farinelli, Mancini, Ermeti, Migliori, Gb, Ambrosetti, M, Fattorini, L, Penati, V, Vaccarino, P, Besozzi, G, Ortona, L, Saltini, C, Orefici, G, Moro, Ml, Iona, E, Cassone, A, De Santis, A, Giorgio, V, Vinciguerra, P, Angarano, G, Petrozzi, L, Costa, D, Gozzellino, F, Perboni, A, Marchetti, D, Pascali, A, Falcone, F, Mariano, V, Rizza, F, Pretto, P, Turano, A, Matteelli, A, Carosi, Gp, Tedoldi, S, Pinsi, G, Farris, Ag, Ligia, Gp, Orani, G, Farris, B, Foschi, C, Trucco, G, Aiolfi, S, Ceruti, T, Parpanesi, M, Calabro, S, Felisatti, G, Tortoli, E, Nutini, S, Montini, G, Fiorentini, F, D'Ambrosio, V, Ceraminiello, A, Bernorio, S, Buono, L, Montesano, P, Vinci, E, Sabato, E, Gamba, S, Crepaldi, P, Bertoli, G, Rupianesi, F, Losi, M, Richeldi, L, Ferrara, G, Muccio, E, Napolitano, G, Molinari, Gl, Saini, L, Garzone, A, Vertuccio, C, Marcias, Menozzi, Marone, P, Peona, Nascimbene, Pasi, Cascina, Casali, Monaco, Penza, Pasticci, M., B., Bistoni, Sposini, Colorizio, Confalonieri, M, Bottrighi, P, Orsi, Schiavi, Macor, Moretti, Fatigante, Barbaro, Agati, Zacarra, Viola, Le, Donne, Farinelli, Mancini, and Ermeti

Subjects
Tuberculosi, Drug susceptibility testing, Proficiency testing
Published
2000

13. Improved Cosmological Constraints from New, Old and Combined Supernova Datasets

Author

Kowalski, M, Rubin, D, Aldering, G, Agostinho, RJ, Amadon, A, Amanullah, R, Balland, C, Barbary, K, Blanc, G, Challis, PJ, Conley, A, Connolly, NV, Covarrubias, R, Dawson, KS, Deustua, SE, Ellis, R, Fabbro, S, Fadeyev, V, Fan, X, Farris, B, Folatelli, G, Frye, BL, Garavini, G, Gates, EL, Germany, L, Goldhaber, G, Goldman, B, Goobar, A, Groom, DE, Haissinski, J, Hardin, D, Hook, I, Kent, S, Kim, AG, Knop, RA, Lidman, C, Linder, EV, Mendez, J, Meyers, J, Miller, GJ, Moniez, M, Mourao, AM, Newberg, H, Nobili, S, Nugent, PE, Pain, R, Perdereau, O, Perlmutter, S, Phillips, MM, Prasad, V, Quimby, R, Regnault, N, Rich, J, Rubenstein, EP, Ruiz-Lapuente, P, Santos, FD, Schaefer, BE, Schommer, RA, Smith, RC, Soderberg, AM, Spadafora, AL, Strolger, L-G, Strovink, M, Suntzeff, NB, Suzuki, N, Thomas, RC, Walton, NA, Wang, L, Wood-Vasey, WM, Yun, JL, Project, SC, Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC), APC - Cosmologie, AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), California Institute of Technology (CALTECH), Department of Physics, Stockholm University, Laboratoire de l'Accélérateur Linéaire (LAL), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Supernova Cosmology Project, Fundação para a Ciência e a Tecnologia (Portugal), German Research Foundation, Department of Energy (US), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Physique Corpusculaire et Cosmologie - Collège de France (PCC), and Collège de France (CdF)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Collège de France (CdF)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[SDU.ASTR.CO]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO], media_common.quotation_subject, Astrophysics::High Energy Astrophysical Phenomena, Cosmological parameters, Supernovae: general, FOS: Physical sciences, Astrophysics, Cosmological constant, Astrophysics::Cosmology and Extragalactic Astrophysics, Astronomy & Astrophysics, Type (model theory), Atomic, 01 natural sciences, 7. Clean energy, [PHYS.ASTR.CO]Physics [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO], Particle and Plasma Physics, astro-ph, 0103 physical sciences, Nuclear, cosmological parameters, 010303 astronomy & astrophysics, Astrophysics::Galaxy Astrophysics, media_common, Physics, [SDU.ASTR]Sciences of the Universe [physics]/Astrophysics [astro-ph], 010308 nuclear & particles physics, Equation of state (cosmology), Cosmology: observations, Astrophysics (astro-ph), Molecular, Astronomy and Astrophysics, observations [cosmology], Redshift, Universe, Supernova, Space and Planetary Science, Dark energy, High Energy Physics::Experiment, Supernova Legacy Survey, general [supernovae], Astronomical and Space Sciences, Physical Chemistry (incl. Structural)
Abstract

30 pags., 17 figs., 12 tabs. 4 apps., We present a new compilation of Type Ia supernovae (SNe Ia), a new data set of low-redshift nearby-Hubble-flow SNe, and new analysis procedures to work with these heterogeneous compilations. This >Union> compilation of 414 SNe Ia, which reduces to 307 SNe after selection cuts, includes the recent large samples of SNe Ia from the Supernova Legacy Survey and ESSENCE Survey, the older data sets, as well as the recently extended data set of distant supernovae observed with the Hubble Space Telescope (HST). A single, consistent, and blind analysis procedure is used for all the various SN Ia subsamples, and a new procedure is implemented that consistently weights the heterogeneous data sets and rejects outliers. We present the latest results from this Union compilation and discuss the cosmological constraints from this new compilation and its combination with other cosmological measurements (CMB and BAO). The constraint we obtain from supernovae on the dark energy density is ¿¿ = 0.713+ 0.027¿0.029(stat)+ 0.036¿0.039(sys) , for a flat, ¿CDM universe. Assuming a constant equation of state parameter, w, the combined constraints from SNe, BAO, and CMB give w = ¿ 0.969+ 0.059¿0.063(stat)+ 0.063¿0.066(sys) . While our results are consistent with a cosmological constant, we obtain only relatively weak constraints on a w that varies with redshift. In particular, the current SN data do not yet significantly constrain w at z > 1. With the addition of our new nearby Hubble-flow SNe Ia, these resulting cosmological constraints are currently the tightest available., This work was supported in part by the Director, Office of Science, Office of High Energy and Nuclear Physics, US Department of Energy, through contract DE-AC02-05CH11231. This research used resources of the National Energy Research Scientific Computing Center, which is supported by the Office of Science of the US Department of Energy under contract DEAC02- 05CH11231. The use of Portuguese time for the YALO telescope was supported by Fundacao para a Ciencia e Tecnologia, Portugal, and by Project PESO/ESO/P/PRO/1257/98. M. K. acknowledges support from the Deutsche Forschungsgemeinschaft (DFG). P. E. N. acknowledges support from the USDepartment of Energy Scientific Discovery throughAdvanced Computing program under contract DE-FG02-06ER06-04. A.M. M. acknowledges financial support from Fundacao para a Ciencia e Tecnologia (FCT), Portugal, through project PESO/P/PRO/ 15139/99.

Published
2008

14. EDU-CARE®, a randomised, multicentre, parallel group study on education and quality of life in COPD

Author

Carone, M., Bertolott, G., Cerveri, I., De Benedetto, F., Fogliani, V., Nardini, S., Portalone, L., Rossi, A., Sanguinetti, C. M., Schiavina, M., Manenti, C. F. Donner on behalf of Edu-Care working group(G., Zanello, A., Balestra, F., Di Gregorio, A., Benamati, G., Quaglia, A., Bonavia, M., Pela, R., Mignini, D., Occhionero, L., Terreno, M., D’Avanzo, Areopagita, A., De Tullio, R., Gatta, E., Moretti, A. M., Brindicci, C., Arnone, P., Cavalli, A., Prati, M., Fabiani, A., Pederzoli, M., Donazzan, G., Begher, G., Tassi, G., Nava, A. M., Sabatti, C., Dal Negro, R., Trevisan, F., Pomari, C., Ligia, G. P., Sortino, E., Rosetti, L., Murgia, A., Piccolini, E., Casazza, M. P., Cioffi, R., Di Salvatore, F., Mirabella, S., Porto, G., De Francesca, F., Polverino, M., Santoriello, C., Fiorenzano, G., D’Intino, A., Idotta, G., Marcolongo, A., Balduin, R., Macaluso, S., Sugamiele, M., Peralta, G., Potena, A., Piattella, M., Corrado, A., Villella, G., Vincenzi, U., Cisternino, L., Fiorentini, F., Colinelli, C., Franco, C., Di Tommasi, M., Perrella, A., Dottorini, M. L., Branca, M. G., Peccini, F., Greco, P., Farris, B., Colorizio, V., Meccia, A., Munafò, G., Zanini, R., Sarni, A., Scoditti, S., Toma, P., Pancosta, G., Marchesani, F., Cipolla, G., Roggi, G., Monacci, A., Ruggeri, S., D’Anneo, R., Centanni, S., Legnani, P. Carlucci – Milano: D., Raiteri, D., Vitale, T., Cirocco, A., Carifi, S., Cocco, G., Iodice, F., De Michele, F., Cecarini, L., Ferrara, G., Di Gregorio, S., Fulgoni, P., Dottorini, M., Baglioni, S., Eslami, A., Ugolini, M., Dennetta, D., Bottrighi, P., Innocenti, F., Fabbri, A., Sanna, A., Celano, M., Tobia, N., Battiloro, R., Lamorgese, V., Castellana, G., Agati, G., Costarella, L., Altieri, A. M., D’Antonio, S., Dominici, M., De Angelis, G., Propati, A., Sini, A., Albergati, M., Viola, B., Rizzo, S., Dalmasso, F., Cordola, G., Santelli, G., Faccini, E., Confalonieri, M, Nabergoj, M., Ciani, F., Basile, G., Cipriani, A., Broseghini, C., Festi, G., Donner, C. F., D’Anna, S., Barbano, G., and G. Bazzerla).

Subjects
quality of life, copd, educational program
Published
2002

15. The Italian AIPO study on tuberculosis treatment results, report 1997. National AIPO 'Tuberculosis' Study Group

Author

Ambrosetti M, Besozzi G, luigi codecasa, Farris B, Nutini S, Saini L, Casali L, Nardini S, and Gb, Migliori

Subjects
Adult, Aged, 80 and over, Male, Adolescent, Middle Aged, Treatment Outcome, Italy, Risk Factors, Child, Preschool, Humans, Female, Child, Tuberculosis, Pulmonary, Aged
Abstract

In Italy no national data have been available on tuberculosis (TB) treatment results. In 1995 the AIPO (Italian Association of Hospital Pneumologists) TB Study Group, in collaboration with the Istituto Superiore di Sanità (technical branch of the Ministry of Health) started a prospective monitoring activity based on the recommendations of the World Health Organization and the International Union Against Tuberculosis and Lung Disease. The aim of this study was to analyse the case findings and treatment results during 1997. Data were collected from a representative network of TB units nation-wide, managing a significant proportion of all TB cases notified in Italy each year. A total of 715 TB cases were reported (56% males; 24% immigrants), of which 635 (89%) were new cases. Of these cases 493 (69%) were pulmonary, 187 (26%) extra-pulmonary cases and 35 (5%) both pulmonary and extrapulmonary. The main risk factors for TB were history of recent contact and diabetes among native Italians, human immunodeficiency virus-seropositive status and a history of recent contact among immigrants. The majority of immigrants came from Africa and Central and South America, and stayed in Italy for more than 24 months before the diagnosis of TB was made. Thirty-six per cent of patients had a positive direct sputum smear examination for alcohol acid-fast bacilli and 27% were resistant to any drug (monoresistance to isoniazid: 2.4%; multi-drug resistance: 7.5%). In 97% of cases the duration of treatment was12 months. The overall success rate (cured plus treatment completed) was 78.1%. A significantly higher percentage of deaths, which was age related, was found in native Italians, while immigrants had a higher default rate. In conclusion, case finding and treatment results in Italy in 1997 are similar to those described in 1995 and 1996.

Published
2000

16. Surveillance of anti-tuberculosis drug resistance: Results of the 1998/1999 proficiency testing in Italy

Author

Migliori, Gb, Ambrosetti, M, Fattorini, L, Penati, V, Vaccarino, P, Besozzi, G, Ortona, L, Saltini, C, Orefici, G, Moro, Ml, Iona, E, Cassone, A, De Santis, A, Giorgio, V, Vinciguerra, P, Angarano, G, Petrozzi, L, Costa, D, Gozzellino, F, Perboni, A, Marchetti, D, Pascali, A, Falcone, F, Mariano, V, Rizza, F, Pretto, P, Turano, A, Matteelli, A, Carosi, Gp, Tedoldi, S, Pinsi, G, Farris, Ag, Ligia, Gp, Orani, G, Farris, B, Foschi, C, Trucco, G, Aiolfi, S, Ceruti, T, Parpanesi, M, Calabro, S, Felisatti, G, Tortoli, E, Nutini, S, Montini, G, Fiorentini, F, D'Ambrosio, V, Ceraminiello, A, Bernorio, S, Buono, L, Montesano, P, Vinci, E, Sabato, E, Gamba, S, Crepaldi, P, Bertoli, G, Rupianesi, F, Losi, M, Richeldi, L, Ferrara, G, Muccio, E, Napolitano, G, Molinari, Gl, Saini, L, Garzone, A, Vertuccio, C, Marcias, Menozzi, Marone, P, Peona, Nascimbene, Pasi, Cascina, Casali, Monaco, Penza, Pasticci, M. B., Bistoni, Sposini, Colorizio, Confalonieri, M, Bottrighi, P, Orsi, Schiavi, Macor, Moretti, Fatigante, Barbaro, Agati, Zacarra, Viola, Donne, Le, Farinelli, Mancini, and Ermeti

Subjects
Drug susceptibility testing, Tuberculosis, Proficiency testing
Published
2000

17. The Italian AIPO study on tuberculosis treatment results, report 1995. National AIPO 'Tuberculosis' Study Group

Author

Ambrosetti M, Besozzi G, luigi codecasa, Farris B, Nutini S, Saini L, Casali L, Nardini S, and Gb, Migliori

Subjects
Cohort Studies, Male, Treatment Outcome, Italy, Risk Factors, Incidence, Outcome Assessment, Health Care, Antitubercular Agents, Humans, Drug Resistance, Microbial, Female, Emigration and Immigration, Tuberculosis, Pulmonary
Abstract

In Italy, no national data on tuberculosis (TB) treatment results were available. In 1995, the AIPO (Italian Association of Hospital Pneumologists) TB Study Group, in collaboration with the Istituto Superiore di Sanità (technical branch of the Ministry of Health), started a prospective monitoring activity based on World Health Organization (WHO) and International Union against Tuberculosis and Lung Disease (IUATLD) recommendations. Data were collected from a nationwide network of 41 TB units, managing a significant proportion of all TB cases notified in Italy each year. The aim of this study was to analyse the case findings and treatment results for the year 1995. Seven hundred and seventy eight TB cases were reported (59% males; 21% immigrants), 640 (82%) being new cases. Of these cases, 517 (66%) were pulmonary, 239 (31%) extrapulmonary and 22 (3%) both pulmonary and extrapulmonary. The main risk factors for TB were a history of recent contact and alcohol abuse among native Italians and human immunodeficiency virus-seropositive status among immigrants. The majority of immigrants were from Africa and South America, and had been in Italy24 months before diagnosis of TB. Thirty-seven per cent of patients had a positive direct sputum smear examination for alcohol acid-fast bacilli; 20% were resistant to any drug (monoresistance to isoniazid 3.5%; multidrug resistance 5.2%). In 95% of cases, the duration of treatment was12 months. The overall success rate (cured plus treatment completed) was 81.1%. A significantly higher percentage of deaths was found in native Italians (being age-related), whereas immigrants had a higher default rate.

Published
1999

18. Cost-comparison of different management policies for tuberculosis patients in Italy. AIPO TB Study Group

Author

Migliori, G. B., Ambrosetti, M., Besozzi, G., Farris, B., Nutini, S., Saini, L., Casali, L., Nardini, S., Bugiani, M., Neri, M., and Raviglione, M. C.

Subjects
Treatment Outcome, Cost Control, Italy, Cost-Benefit Analysis, Health Policy, Humans, Tuberculosis, Prospective Studies, Research Article
Abstract

Although in developing countries the treatment of tuberculosis (TB) cases is among the most cost-effective health interventions, few studies have evaluated the cost-effectiveness of TB control in low-prevalence countries. The aim of the present study was to carry out an economic analysis in Italy that takes into account both the perspective of the resource-allocating authority (i.e. the Ministry of Health) and the broader social perspective, including a cost description based on current outcomes applied to a representative sample of TB patients nationwide (admission and directly observed treatment (DOT) during the initial intensive phase of treatment); a cost-comparison analysis of two alternative programmes: current policy based on available data (scenario 1) and an hypothetical policy oriented more towards outpatient care (scenario 2) (both scenarios included the option of including or not including DOT outside hospital admission, and incentives) were compared in terms of cost per case treated successfully. Indirect costs (such as loss of productivity) were included in considerations of the broader social perspective. The study was designed as a prospective monitoring activity based on the supervised collection of forms from a representative sample of Italian TB units. Individual data were collected and analysed to obtain a complete economic profile of the patients enrolled and to evaluate the effectiveness of the intervention. A separate analysis was done for each scenario to determine the end-point at different levels of cure rate (50-90%). The mean length of treatment was 6.6 months (i.e. patients hospitalized during the intensive phase; length of stay was significantly higher in smear-positive patients and in human immunodeficiency virus (HIV) seropositive patients). Roughly six direct smear and culture examinations were performed during hospital admission and three during ambulatory treatment. The cost of a single bed day was US$186.90, whereas that of a single outpatient visit ranged, according to the different options, from US$2.50 to US$11. Scenario 2 was consistently less costly than scenario 1. The cost per case cured for smear-positive cases was US$16,703 in scenario 1 and US$5946 in scenario 2. The difference in cost between the cheapest option (no DOT) and the more expensive option (DOT, additional staff, incentives) ranged from US$1407 (scenario 1, smear-negative and extrapulmonary cases) to US$1814 (scenario 2, smear-positive cases). The additional cost to society including indirect costs ranged from US$1800 to US$4200. The possible savings at the national level were in the order of US$50 million per year. In conclusion, cost-comparison analysis showed that a relatively minor change in policy can result in significant savings and that the adoption of DOT will represent a relatively modest economic burden, although the real gain in effectiveness resulting from DOT in Italy requires further evaluation.

Published
1999

19. Improved Cosmological Constraints from New, Old, and Combined Supernova Data Sets

Author

Fundação para a Ciência e a Tecnologia (Portugal), German Research Foundation, Department of Energy (US), Kowalski, M., Rubin, D., Aldering, G., Agostinho, R. J., Amadon, A., Amanullah, R., Balland, C., Barbary, K., Blanc, G., Challis, P. J., Conley, A., Connolly, N. V., Covarrubias, R., Dawson, K.S., Deustua, S. E., Ellis, R., Fabbro, S., Fadeyev, V., Fan, X., Farris, B., Folatelli, G., Frye, B.L., Garavini, G., Gates, E. L., Germany, L., Goldhaber, G., Goldman, B., Goobar, A., Groom, D. E., Haissinski, J., Hardin, D., Hook, I., Kent, S., Kim, A. G., Knop, R. A., Lidman, C., Linder, E.V., Méndez, J., Meyers, J., Miller, G. J., Moniez, M., Mourão, A. M., Newberg, H., Nobili, S., Nugent, P. E., Pain, R., Perdereau, O., Perlmutter, S., Phillips, M. M., Prasad, V., Quimby, R., Regnault, N., Rich, J., Rubenstein, E. P., Ruiz-Lapuente, Pilar, Santos, F. D., Schaefer, B. E., Schommer, R. A., Smith, R. C., Soderberg, A. M., Spadafora, A. L., Strolger, L. G., Strovink, M., Suntzeff, Nicholas B., Suzuki, N., Thomas, R. C., Walton, N. A., Wang, L., Wood-Vasey, W. M., Yun, J. L., Fundação para a Ciência e a Tecnologia (Portugal), German Research Foundation, Department of Energy (US), Kowalski, M., Rubin, D., Aldering, G., Agostinho, R. J., Amadon, A., Amanullah, R., Balland, C., Barbary, K., Blanc, G., Challis, P. J., Conley, A., Connolly, N. V., Covarrubias, R., Dawson, K.S., Deustua, S. E., Ellis, R., Fabbro, S., Fadeyev, V., Fan, X., Farris, B., Folatelli, G., Frye, B.L., Garavini, G., Gates, E. L., Germany, L., Goldhaber, G., Goldman, B., Goobar, A., Groom, D. E., Haissinski, J., Hardin, D., Hook, I., Kent, S., Kim, A. G., Knop, R. A., Lidman, C., Linder, E.V., Méndez, J., Meyers, J., Miller, G. J., Moniez, M., Mourão, A. M., Newberg, H., Nobili, S., Nugent, P. E., Pain, R., Perdereau, O., Perlmutter, S., Phillips, M. M., Prasad, V., Quimby, R., Regnault, N., Rich, J., Rubenstein, E. P., Ruiz-Lapuente, Pilar, Santos, F. D., Schaefer, B. E., Schommer, R. A., Smith, R. C., Soderberg, A. M., Spadafora, A. L., Strolger, L. G., Strovink, M., Suntzeff, Nicholas B., Suzuki, N., Thomas, R. C., Walton, N. A., Wang, L., Wood-Vasey, W. M., and Yun, J. L.

Abstract

We present a new compilation of Type Ia supernovae (SNe Ia), a new data set of low-redshift nearby-Hubble-flow SNe, and new analysis procedures to work with these heterogeneous compilations. This >Union> compilation of 414 SNe Ia, which reduces to 307 SNe after selection cuts, includes the recent large samples of SNe Ia from the Supernova Legacy Survey and ESSENCE Survey, the older data sets, as well as the recently extended data set of distant supernovae observed with the Hubble Space Telescope (HST). A single, consistent, and blind analysis procedure is used for all the various SN Ia subsamples, and a new procedure is implemented that consistently weights the heterogeneous data sets and rejects outliers. We present the latest results from this Union compilation and discuss the cosmological constraints from this new compilation and its combination with other cosmological measurements (CMB and BAO). The constraint we obtain from supernovae on the dark energy density is ¿¿ = 0.713+ 0.027¿0.029(stat)+ 0.036¿0.039(sys) , for a flat, ¿CDM universe. Assuming a constant equation of state parameter, w, the combined constraints from SNe, BAO, and CMB give w = ¿ 0.969+ 0.059¿0.063(stat)+ 0.063¿0.066(sys) . While our results are consistent with a cosmological constant, we obtain only relatively weak constraints on a w that varies with redshift. In particular, the current SN data do not yet significantly constrain w at z > 1. With the addition of our new nearby Hubble-flow SNe Ia, these resulting cosmological constraints are currently the tightest available.

Published
2008

20. 66-P

Author

Tumer, Gizem, primary, Roberts-Wilson, Tiffany K., additional, Alton, Farris B., additional, Lauren, Stuart N., additional, Gebel, Howard M., additional, and Bray, Robert A., additional

Published
2013
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21. 66-P

Author

Gizem Tumer, Robert A. Bray, Farris B. Alton, Tiffany K. Roberts-Wilson, Howard M. Gebel, and Stuart N. Lauren

Subjects
medicine.medical_specialty, Pathology, medicine.diagnostic_test, business.industry, Mean fluorescence intensity, Donor specific antibodies, Immunology, General Medicine, Human leukocyte antigen, Gastroenterology, Correlation, Internal medicine, Antibody mediated rejection, Biopsy, medicine, Immunology and Allergy, Immunohistochemistry, Renal biopsy, business
Abstract

Aim To analyze the relationship between AMR, renal biopsy C4d staining and circulating DSA (MFI) levels. Methods Twenty four patients with confirmed DSAs and allograft biopsies were evaluated. HLA class I and II DSAs in sera collected at the time of biopsy were identified by a Luminex-based, Single Antigen Bead assay. C4d scoring was performed by immunohistochemistry. Patients with biopsy proven AMR were further classified by summing Banff scoring of peritubular capillaritis (ptc; scale of 0 to 3) and glomerulitis (g; scale of 0 to 3). Totals (ptc+g) were subdivided as mild (0-2), moderate (3, 4), and severe (5, 6). Results Seventeen patients were diagnosed with AMR: 10 experienced mild AMR, 3 moderate AMR and 4 severe AMR. All severe AMR patients possessed both HLA class I and class II DSAs (MFI range: 2600-24000). Of the 3 patients with moderate AMR, one had only class I, one had only class II, and one had both (MFI range: 3000-24000). Among patients with mild AMR 5 had class I only, 2 had class II only and the remaining 3 had both class I and class II DSAs (MFI range:1800-24000). AMR was not diagnosed in 7 DSA+ patients. Six of these patients only displayed class II DSAs (MFI range: 2200-25000). One patient had only class I DSA (MFI = 5100). [figure1] Conclusions This study demonstrates that the MFI levels of donor specific antibodies do not predict whether biopsies will be C4d positive or negative. Furthermore, MFI levels of DSAs are not predictive of the presence of AMR.

Published
2013

27. Oppenheimer-Snyder collapse in moving-puncture coordinates.

Author

Staley, A. N., Baumgarte, T. W., Brown, J. D., Farris, B., and Shapiro, S. L.

Subjects
BLACK holes, CURVATURE cosmology, RELATIVITY (Physics), GRAVITATIONAL collapse, SPACETIME, SCHWARZSCHILD black holes
Abstract

Abstract Moving puncture coordinates are commonly used in numerical simulations of black holes. Their properties for vacuum Schwarzschild black holes have been analyzed in a number of studies. The behavior of moving-puncture coordinates in spacetimes containing matter, however, is less well understood. In this paper, we explore the behavior of these coordinates forOppenheimer-Snyder collapse, i.e. the collapse of a uniform density, pressureless sphere of dust initially at rest to a black hole. Oppenheimer-Snyder collapse provides a stringent test of the singularity-avoiding properties of moving-puncture coordinates, since the singularity can form more quickly than it would for matter with pressure. Our results include analytical expressions for the matter density, lapse function and mean curvature at early times, as well as interesting limits for later times. We also carry out numerical simulations to obtain the full solution and these show that even in the absence of pressure, moving-puncture coordinates are able to avoid the singularity. At late times, the geometry settles down to a trumpet slice of a vacuum black hole. [ABSTRACT FROM AUTHOR]

Published
2012
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29. Defining a combat decision-making process at the tactical level of war and operations other than war.

Author

Farris, B. Don, II, Farris, B. Don, II, Farris, B. Don, II, and Farris, B. Don, II

Abstract

This study challenges the deliberate decision making process (DDMP) as ineffective for use by commanders in time-constrained environments. FM 101-5 (final draft), Command and Control for Commanders and Staff, 1995, currently prescribes DDMP as the only accepted process at the tactical level for both war and operations other than war. The researcher suggests a second, quicker and more flexible doctrinal methodology to supplement DDMP when planning time is limited. DDMP relies on a traditional, analytical approach of generating and concurrently evaluating options allowing commanders to make an "optimal" decision. This study explores the existing theory and relevance of "satisficing." When planning time is limited, the initial course of action developed by the commander may prove more effective than one arrived at after the careful consideration of options. This theoretical approach provides the framework for a proposed combat decision making model. Using the doctrinal characteristics of an effective decision making process, both DDMP and the proposed model are compared. The study concludes that the proposed combat decision-making process should replace DDMP in fluid, time-constrained environments.

32. Surveillance of anti-tuberculosis drug resistance: Results of the 1998/1999 proficiency testing in Italy

Author

Migliori, G. B., Ambrosetti, M., Fattorini, L., Penati, V., Vaccarino, P., Besozzi, G., Ortona, L., Saltini, C., Orefici, G., Moro, M. L., Iona, E., Cassone, A., Santis, A., Giorgio, V., Vinciguerra, P., Angarano, G., Petrozzi, L., Costa, D., Gozzellino, F., Perboni, A., Marchetti, D., Pascali, A., Falcone, F., Mariano, V., Rizza, F., Pretto, P., Turano, A., Alberto Matteelli, Carosi, G. P., Tedoldi, S., Pinsi, G., Farris, A. G., Ligia, G. P., Orani, G., Farris, B., Foschi, C., Trucco, G., Aiolfi, S., Ceruti, T., Parpanesi, M., Calabro, S., Felisatti, G., Tortoli, E., Nutini, S., Montini, G., Fiorentini, F., D Ambrosio, V., Ceraminiello, A., Bernorio, S., Buono, L., Montesano, P., Vinci, E., Sabato, E., Gamba, S., Crepaldi, P., Bertoli, G., Rupianesi, F., Losi, M., Richeldi, L., Ferrara, G., Minuccio, E., Napolitano, G., Molinari, G. L., Saini, L., Garzone, A., Vertuccio, C., Marcias, S., Menozzi, M., Marone, P., Peona, V., Nascimbene, C., Pasi, A., Cascina, A., Casali, L., Monaco, A., Penza, O., Pasticci, M. B., Bistoni, F., Sposini, T., Colorizio, V., Confalonieri, M., Bottrighi, P., Orsi, A., Schiavi, L., Macor, G., Moretti, G., Fatigante, R., Barbaro, A., Agati, G., Zacarra, F., Viola, S., Le Donne, R., Farinelli, G., Mancini, D., and Ermeti, M.

34. Prevalence of resistance to anti-tuberculosis drugs: Results of the 1998/99 national survey in Italy

Author

Giovanni Battista Migliori, Fattorini, L., Vaccarino, R., Besozzi, G., Saltini, C., Orefici, G., Iona, E., Matteelli, A., Fiorentini, F., Codecasa, L. R., Casali, L., Cassone, A., Santis, A., Giorgio, V., Vinciguerra, P., Angarano, G., Petrozzi, L., Costa, D., Gozzellino, F., Perboni, A., Marchetti, D., Pascali, A., Falcone, F., Mariano, V., Rizza, F., Pretto, P., Turano, A., Carosi, G. P., Farris, A. G., Ligia, G. P., Orani, G., Farris, B., Foschi, C., Trucco, G., Aiolfi, S., Ceruti, T., Parpanesi, M., Calabro, S., Felisatti, G., Tortoli, E., Nutini, S., Montini, G., D Ambrosio, V., Ceraminiello, A., Bernorio, S., Buono, L., Montesano, P., Vinci, E., Sabato, E., Gamba, S., Crepaldi, P., Magliano, E., Penati, V., Vaccarino, P., Astolfi, A., Bertoli, G., Rupianesi, F., Losi, M., Richeldi, L., Ferrara, G., Minuccio, E., Napolitano, G., Molinari, G. L., Saini, L., Garzone, A., Vertuccio, C., Marcias, S., Menozzi, M., Marone, P., Peona, V., Nascimbene, C., Pasi, A., Cascina, A., Monaco, A., Penza, O., Pasticci, M. B., Bistoni, F., Sposini, T., Colorizio, V., Confalonieri, M., Bottrighi, P., Macor, G., Moretti, G., Fatigante, R., Barbaro, A., Agati, G., Zaccara, F., Viola, S., Le Donne, R., Farinelli, G., Mancini, D., Ermeti, M., Longi, R., Tronci, M., Bisetti, A., Altieri, A., and Fadda, G.

35. Evaluation of tuberculosis treatment results in Italy, report 1998

Author

Centis, R., Ianni, A., Migliori, G. B., Casali, L., Agati, G., Aiolfi, S., Altieri, A., Ambrosetti, M., Angarano, G., Arossa, W., Bagnasco, G., Bazzerla, G., Berra, A., Besozzi, G., Bottrighi, P., Bugiani, M., Calabro, S., Castiglioni, G., Cavallero, M., Cicchitto, G., luigi codecasa, Colorizio, V., Confalonieri, M., D Ambrosio, L., D Ambrosio, V., Dellatommasa, S., Di Pisa, G., Ermeti, M., Faccini, E., Falcone, F., Farinelli, G., Fatigante, R., Farris, B., Fatur Volante, T., Felisatti, G., Ferranti, P., Fiorentini, F., Foschi, C., Garzone, A., Giorgio, V., Gozzellino, F., Jacopino, L., Lauriello, G., Le Donne, R., Longi, R., Macor, G., Mancini, D., Marchesani, M. F., Marcias, S., Mariano, V., Mennea, G., Monaco, A., Montesano, G., Moretti, G., Napolitano, G., Nardini, S., Nutini, S., Orani, G., Orsi, A., Parpanesi, M., Pasi, A., Penza, O., Perboni, A., Petrozzi, L., Pretto, P., Rossi, S., Sabato, E., Saini, L., Schiavi, L., Tazza, R., Trucco, G., Vertuccio, C., Viviani, U., Volante, M., Vinciguerra, P., Viola, S., Zaccara, F., Barelle, L., Bertoli, G., Bisetti, A., Bistoni, F., Buono, L., Carbonara, S., Carosi, G. P., Cascina, A., Cassone, A., Costa, D., Crepaldi, P., Santis, A., Diamare, F., Fabbro, L., Fadda, G., Farris, A. G., Fattorini, L., Ferrara, G., Gamba, S., Iona, E., and Losi, M.

43. Intelligent downhole production control improves project economics, lowers risk.

Author

Chen, J. H. Chris, Azrul, N. M., Farris, B. M., Nurhazrina, K. Z., Aminuddin, M. K. M., Anuar, M. Y. Saiful, Goh, K. F. Gordon, Kaur, K. S. Premjit, Luke, T. K. Darren, and Eddep, A.

Subjects
PETROLEUM reserves, OFFSHORE oil well drilling, PETROLEUM production, PRODUCTION control, PETROLEUM industry
Abstract

The article discusses the solution to the challenges in an offshore field with multi-stacked reservoirs. These challenges include zonal gas-out, moderate aquifer strength and water invasion. It offers information on the IntelliZone Compact modular multi-zonal management system that met all the requirements of cost-effectiveness and a fit-for-purpose deployment.

Published
2012

45. 66-P: NO DIRECT CORRELATION BETWEEN DONOR SPECIFIC ANTIBODY (DSA) MEAN FLUORESCENCE INTENSITY (MFI) AND C4d POSITIVITY IN ANTIBODY MEDIATED REJECTION (AMR).

Author

Tumer, Gizem, Roberts-Wilson, Tiffany K., Alton, Farris B., Lauren, Stuart N., Gebel, Howard M., and Bray, Robert A.

Subjects
*RENAL biopsy, *HLA histocompatibility antigens, *ORGAN donors, *IMMUNOGLOBULINS, *ANTIGENS, *HOMOGRAFTS, *GRAFT rejection, *IMMUNOHISTOCHEMISTRY
Abstract

Aim: To analyze the relationship between AMR, renal biopsy C4d staining and circulating DSA (MFI) levels. Methods: Twenty four patients with confirmed DSAs and allograft biopsies were evaluated. HLA class I and II DSAs in sera collected at the time of biopsy were identified by a Luminex-based, Single Antigen Bead assay. C4d scoring was performed by immunohistochemistry. Patients with biopsy proven AMR were further classified by summing Banff scoring of peritubular capillaritis (ptc; scale of 0 to 3) and glomerulitis (g; scale of 0 to 3). Totals (ptc+g) were subdivided as mild (0-2), moderate (3, 4), and severe (5, 6). Results: Seventeen patients were diagnosed with AMR: 10 experienced mild AMR, 3 moderate AMR and 4 severe AMR. All severe AMR patients possessed both HLA class I and class II DSAs (MFI range: 2600-24000). Of the 3 patients with moderate AMR, one had only class I, one had only class II, and one had both (MFI range: 3000-24000). Among patients with mild AMR 5 had class I only, 2 had class II only and the remaining 3 had both class I and class II DSAs (MFI range:1800-24000). AMR was not diagnosed in 7 DSA+ patients. Six of these patients only displayed class II DSAs (MFI range: 2200-25000). One patient had only class I DSA (MFI = 5100). [figure1] Conclusions: This study demonstrates that the MFI levels of donor specific antibodies do not predict whether biopsies will be C4d positive or negative. Furthermore, MFI levels of DSAs are not predictive of the presence of AMR. [Copyright &y& Elsevier]

Published
2013
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47. Massive Black Hole Science with eLISA

Author

Kelly Holley-Bockelmann, Bangalore Suryanarayana Sathyaprakash, Emanuele Berti, Enrico Barausse, Alberto Sesana, Brian D. Farris, Jillian Bellovary, Institut d'Astrophysique de Paris (IAP), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Department of Physics and Astronomy [Nashville], Vanderbilt University [Nashville], Fisk University, Department of Physics and Astronomy [U Mississippi], The University of Mississippi [Oxford], New York University [New York] (NYU), NYU System (NYU), Columbia University [New York], School of Physics and Astronomy [Cardiff], Cardiff University, Max-Planck-Institut für Gravitationsphysik ( Albert-Einstein-Institut ) (AEI), Max-Planck-Gesellschaft, Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC), Barausse, E, Bellovary, J, Berti, E, Holley-Bockelmann, K, Farris, B, Sathyaprakash, B, and Sesana, A

Subjects
High Energy Physics - Theory, History, Astrophysics::High Energy Astrophysical Phenomena, Population, FOS: Physical sciences, Astrophysics::Cosmology and Extragalactic Astrophysics, General Relativity and Quantum Cosmology (gr-qc), 01 natural sciences, 7. Clean energy, Cosmology, General Relativity and Quantum Cosmology, Education, High Energy Physics - Phenomenology (hep-ph), 0103 physical sciences, education, 010303 astronomy & astrophysics, Luminosity distance, Physics, High Energy Astrophysical Phenomena (astro-ph.HE), education.field_of_study, 010308 nuclear & particles physics, Gravitational wave, Astronomy, Galaxy, Redshift, black holes, gravitational waves, Computer Science Applications, Black hole, Dark matter halo, High Energy Physics - Phenomenology, High Energy Physics - Theory (hep-th), 13. Climate action, Astrophysics - High Energy Astrophysical Phenomena, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
Abstract

The evolving Laser Interferometer Space Antenna (eLISA) will revolutionize our understanding of the formation and evolution of massive black holes along cosmic history by probing massive black hole binaries in the $10^3-10^7$ solar mass range out to redshift $z\gtrsim 10$. High signal-to-noise ratio detections of $\sim 10-100$ binary coalescences per year will allow accurate measurements of the parameters of individual binaries (such as their masses, spins and luminosity distance), and a deep understanding of the underlying cosmic massive black hole parent population. This wealth of unprecedented information can lead to breakthroughs in many areas of physics, including astrophysics, cosmology and fundamental physics. We review the current status of the field, recent progress and future challenges., Comment: 22 pages, 3 figures. Minor change (added two references) to match version accepted in the Proceedings of LISA Symposium X (Journal of Physics: Conference Series)

Published
2014
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48. The Role of the Medical Director and Psychiatric Medical Director in Child Welfare Serving Agencies.

Author

Farris B, Hudson M, and Coffey S

Subjects
Humans, Child, Adolescent, Child Psychiatry, Mental Health Services standards, Mental Health Services organization & administration, Physician Executives, Child Welfare
Abstract

Collaboration between the child welfare system and health care practitioners has become increasingly necessary in order to meet the often-significant health needs of system-involved youth. Child welfare medical directors and psychiatric medical directors have been implemented as a means to address this need in several state child welfare systems. Building on the core principles of the National Guidelines for Child and Youth Behavioral Health Crisis Care, medical and psychiatric medical directors can help ensure youth receive the least-restrictive, most appropriate level of behavioral health care; prioritizing care involvement with caregivers in community-based settings., Competing Interests: Disclosure The authors have nothing to disclose., (Copyright © 2024 Elsevier Inc. All rights reserved.)

Published
2024
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49. Ultrafast Dynamics of a "Super" Photobase.

Author

Sheng W, Nairat M, Pawlaczyk PD, Mroczka E, Farris B, Pines E, Geiger JH, Borhan B, and Dantus M

Abstract

Molecular reactivity can change dramatically with the absorption of a photon due to the difference of the electronic configurations between the excited and ground states. Here we report on the discovery of a modular system (Schiff base formed from an aldehyde and an amine) that upon photoexcitation yields a more basic imine capable of intermolecular proton transfer from protic solvents. Ultrafast dynamics of the excited state conjugated Schiff base reveals the pathway for proton transfer, culminating in a 14-unit increase in pK a to give the excited state pK a * >20 in ethanol., (© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Published
2018
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50. Patient nonadherence to filling discharge medication prescriptions from the emergency department: Barriers and clinical implications.

Author

Farris B, Shakowski C, Mueller SW, Phong S, Kiser TH, and Jacknin G

Subjects
Adult, Emergency Service, Hospital standards, Ethnicity, Female, Humans, Insurance Coverage standards, Male, Middle Aged, Patient Discharge standards, Retrospective Studies, Sex Factors, Young Adult, Drug Prescriptions standards, Emergency Service, Hospital trends, Medication Adherence, Patient Discharge trends
Abstract

Purpose: Barriers to and clinical implications of patient nonadherence to filling discharge medication prescriptions from the emergency department (ED) were evaluated., Methods: This was a retrospective, observational analysis of patients discharged from the ED from April 2013 through May 2015 with medication prescriptions. Patients age 18-89 years who were seen in the ED and did not retrieve discharge medication prescriptions from the onsite, 24-hour ED discharge pharmacy were included in this study. Patients who did not pick up prescriptions were called and asked about barriers to prescription filling. These charts were then retrospectively reviewed and categorized. The primary study outcome was the frequency of nonadherence to filling discharge medications prescribed during the ED visit at the ED outpatient pharmacy. Secondary outcomes included identifying barriers to medication adherence, the rate of return ED visits within 30 days of ED discharge, and the rate of 30-day hospital admissions. Associations between patient and medication variables and the rates of return ED visits within 30 days of discharge and 30-day hospital admissions were analyzed., Results: Of the 4,444 patients discharged from the ED with a prescription to be filled at the satellite pharmacy, 510 were nonadherent. Of these patients, 505 had complete chart information available for evaluation. A large proportion of nonadherent patients revisited the ED within 30 days of ED discharge. Multivariate logistic regression found payer class, ethnicity, and sex were independently associated with return ED visits., Conclusion: The majority of patients who received a prescription during an ED visit filled their discharge medications. Sex, ethnicity, and payer class were independently associated with nonadherence., (Copyright © 2018 by the American Society of Health-System Pharmacists, Inc. All rights reserved.)

Published
2018
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