1. Prevalence and risk factors of myasthenia gravis recurrence post-thymectomy
- Author
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Abdulrahman Ali, Ziyad Aljohani, Alanood AlSaleem, Daifallah Almalki, Sultan Al Dalbhi, Noura Alotaibi, Shahla Odeh, and Fatmah Alqarni
- Subjects
Pediatrics ,medicine.medical_specialty ,Time Factors ,Databases, Factual ,business.industry ,medicine.medical_treatment ,MEDLINE ,Thymectomy ,medicine.disease ,Myasthenia gravis ,03 medical and health sciences ,Psychiatry and Mental health ,Treatment Outcome ,0302 clinical medicine ,Recurrence ,Risk Factors ,Myasthenia Gravis ,Prevalence ,Humans ,Medicine ,Systematic Review ,Neurology (clinical) ,business ,030217 neurology & neurosurgery - Abstract
Objectives: To evaluate the prevalence and the factors associated with recurrence of myasthenia gravis following thymectomy. Methods: Six electronic databases which reported on recurrence of myasthenia gravis following thymectomy and/or its risk factors from 1985 to 2018 were searched. Summary prevalence and risk values obtained based on the random effect models were reported. Results: Seventy (70) papers containing 7,287 individuals with myasthenia gravis who received thymectomy as part of their management were retrieved. The patients had a mean follow-up of 4.65 years post-thymectomy. The prevalence of myasthenia gravis recurrence post-thymectomy was 18.0% (95% CI 14.7–22.0%; 1865/7287). Evident heterogeneity was observed (I2=93.6%; p
- Published
- 2021
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