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289 results on '"Fearon, K. C. H."'

1. Diet and Colorectal Cancer Risk: Evaluation of a Nutrition Education Leaflet

Author

Dyer, K. J., Fearon, K. C. H., Buckner, K., and Richardson, R. A.

Abstract

Objective: To evaluate the effect of a needs-based, nutrition education leaflet on nutritional knowledge. Design: Comparison of nutritional knowledge levels before and after exposure to a nutrition education leaflet. Setting: A regional colorectal out-patient clinic in Edinburgh. Method: A nutrition education leaflet, based on an earlier needs-assessment, was used in the study. Patients attending an out-patient clinic with colorectal symptoms were invited to participate. Nutritional knowledge was determined using a validated questionnaire in a semi-structured interview. In Group A, nutritional knowledge was determined at baseline and after exposure to the leaflet. In Group B, nutritional knowledge was determined after exposure to the leaflet and again one month later. Results: In Group A (n = 35), there was a significant increase in awareness of the "5 fruit and vegetables a day" (46 per cent v 91 per cent, p less than 0.001 ) and "what constitutes a portion of fruit and vegetable" messages (38 per cent v 71 per cent, p less than 0.05), compared with baseline. In Group B (n = 52), knowledge levels were maintained after one month, and during this time, 12 (23 per cent) subjects reported an increase in their fruit and vegetable intake. Conclusion: Targeted nutrition education significantly increased levels of nutritional knowledge, which was sustained one month later. Nearly a quarter of the cohort reported improvements in their dietary intake, which suggests that this method of nutrition education may be particularly cost-effective in facilitating dietary change. (Contains 5 tables.)

Published
2005
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3. Diet and Colorectal Cancer Risk: Baseline Dietary Knowledge of Colorectal Patients

Author

Dyer, K. J., Fearon, K. C. H., Buckner, K., and Richardson, R. A.

Abstract

Objective: To establish the dietary knowledge, attitudes and potential barriers to change of patients attending a colorectal outpatient clinic. Design: Use of a semistructured interview to generate qualitative and quantitative data. Setting: A regional colorectal outpatient clinic within Edinburgh. Method: Patients attending clinic with colorectal symptoms were invited to participate in a semistructured interview using a validated questionnaire. Results: Fifty patients (mean age 62 plus or minus SD 15.1 years; male:female = 22:28) were interviewed. Twenty-three (46 per cent) knew that five portions of fruit and vegetable were recommended daily, but 31 (62 per cent) were unclear what constituted a portion. Only three (6 per cent) and two (4 per cent) could name three foods high in fat and fibre, respectively. Twenty-three (46 per cent) were unable to identify why healthy eating is important, while only four (8 per cent) were aware of an association between diet and cancer. Women had significantly higher nutrition knowledge scores than men (16.3 plus or minus SD7.1 v 12.3 plus or minus SD5.1, p less than 0.05 ). There was a significant relationship between educational attainment and nutritional knowledge (r = 0.534, p less than 0.001). Potential barriers to change included the belief that their diet was already healthy (n = 35, 70 per cent) and lack of time (n = 25, 50 per cent). Conclusion: Patients attending a colorectal clinic lack practical dietary knowledge and the majority are unaware of the link between diet and cancer. Targeted health promotion strategies are needed to raise awareness in this group. (Contains 3 tables.)

Published
2004
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13. The value of residual liver volume as a predctor of hepatic dysfunction and infection after major liver resection

Author

Schnidl, M J, Redhead, D N, Fearon, K C H, Garden, O J, and Wigmore, S J

Subjects
Surgical wound infections -- Analysis, Surgical wound infections -- Observations, Liver tumors -- Care and treatment, Liver tumors -- Research, Excision (Surgery) -- Complications and side effects, Excision (Surgery) -- Research, Excision (Surgery) -- Measurement, Excision (Surgery) -- Statistics, Excision (Surgery) -- Analysis, Health
Published
2005

21. Irish Society of Gastroenterology: Proceedings of meeting held November 1990

Author

Coleman, J., Hayes, D. Bouchier, Daw, M. A., O’More, R., Keane, C. T., O’Morain, C., Johnson G. W., Spencer E. F. A., Wilkinson A. J., Kennedy T. L., Collins, J. S. A., Bamford, K. B., Collins, B. J., Sloan, J. M., Moorehead, R. J., Love, A. H. G., McCarthy, C., Collins, R., Beattie, S., McDevitt, J., Feighery, C., O’Farrelly, C., Weir, D. G., Kelleher, D., Whelan, A., Williams, Y., Kellegher, D., Weir, D., Prabhakar, M. C., Daw, M., Keane, F., McDermott E. W. M., Duduric B., Brennan M. F., Gaffney, R., O’Leary, J., Doyle, T., Gaffney, A., Gough, D. B., Fearon, K. C. H., Winstanley, P., Carter, D. C., McAnena, O. J., Moore, F. A., Moore, E. E., Pogetti, R., Peterson, V. M., Abemathy, C. M., Parsons, P., Williams, N. N., Daly, J. M., Herlyn, M., Bouchier-Hayes, D., Course, N. F., Horgan, P. G., Fahy, A., Delaney, C., Fitzpatrick, J. M., Gorey, T. F., Jazrawl S., Walsh T. N., Byrne P. J., Lawlor P., Hennessy T. P. J., O’Sullivan, K. R., Mathias, P. M., McNicholas, M., Logan, M., Masterson, J., Gillen, P., Hyland, J., Beausang, E., Joyce, W. P., Williams, N., Maxwell, W., Reid, I., Sharpe, I., Geraghty, J. G., Tanner, W. A., Patchett, S., Mulcahy, H., Afdhal, N., O’Donoghue, D., Lohan, A., Darzi, A., Keane, F. B. V., Keeling, P. W. N., Gibney, R. C., Keane, R., Drumm, J., Egan, T. J., Delaney, P. V., O’Sullivan, G., Harte, P., Grace, P. A., Qureshi, A., Osbome, H., Bouchier-Hayes, D. J., Bamford, S. L., Geraghty, J., Keane, F. B., Coleman, J. E., Gleeson, A., Mealy, K., Barry, M., Traynor, O., Keating, J. J., Chua, A., Ah-Kion, S., McNulty, J., Heaney, L. G., Murphy, P., Connolly, J. H., Callender, M. E., MacMathuna, P., Farrant, M., Hourihane, D. O. B., Donaldson, P., Lombard, M., Westaby, D., Weir, D. G., Williams, Roger, Couse, N. F., Burke, J., Lennon, G., Delaneyc, C. P., O’Brien, S., O’Brien, A., Fitzgerald, M. X., Hegarty, J. E., Noonan, N., Healy, M., O’Moore, R., Corrigan, O. I., Keating, P. W. N., Li, H. U. I., Byrne, P. J., Lawlor, P., Stuart, R. C., Jazrawi, S., Walsh, T. N., Hennessy, T. P. J., Course, N. F., Wai, D., Jaeger, H., Jackson, A. M., Mitchell, C. J., MacFie, J., Delaney, C. P., McGeeney, K., Caldwell, M. T. P., O’Donoghue, D. P., Connolly J., Stuart R. C., Kay E., Gorey T., Keane R., McKiernan, P., Glasgow, J. F. T., Johnson, B. T., Ferguson, R., Davidson, I., Hurley, J., Keeling, P., Crowley, T., Long, A. A., O’Brien, D. P., Waldron, R. P., Shearer, M. J., Given, H. F., McEntee, G., Monson, J., Donohue, J., Nagomey, D., Trimble, K. C., Molloy, A. M., Scott, J. M., Kay, E., McKeever, J., and Hennessey, T. P. J.

Published
1993
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47. Enhanced Recovery After Surgery (ERAS) for gastrointestinal surgery, part 2: consensus statement for anaesthesia practice

Author

Feldheiser, A., primary, Aziz, O., additional, Baldini, G., additional, Cox, B. P. B. W., additional, Fearon, K. C. H., additional, Feldman, L. S., additional, Gan, T. J., additional, Kennedy, R. H., additional, Ljungqvist, O., additional, Lobo, D. N., additional, Miller, T., additional, Radtke, F. F., additional, Ruiz Garces, T., additional, Schricker, T., additional, Scott, M. J., additional, Thacker, J. K., additional, Ytrebø, L. M., additional, and Carli, F., additional

Published
2015
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48. Plasma MIC-1 correlates with systemic inflammation but is not an independent determinant of nutritional status or survival in oesophago-gastric cancer

Author

Skipworth, R J E, Deans, D A C, Tan, B H L, Sangster, K, Paterson-Brown, S, Brown, D A, Hunter, M, Breit, S N, Ross, James, Fearon, K C H, and Fearon, Kenneth

Subjects
Adult, Male, oesophageal cancer, medicine.medical_specialty, Cancer Research, Growth Differentiation Factor 15, Esophageal Neoplasms, Nutritional Status, macrophage inhibitory cytokine 1, Adenocarcinoma, cachexia, survival, Gastroenterology, Cachexia, Weight loss, Stomach Neoplasms, Internal medicine, Clinical Studies, Blood plasma, medicine, Humans, Stomach cancer, Survival analysis, Aged, Neoplasm Staging, Aged, 80 and over, Inflammation, business.industry, gastric cancer, Stomach, Case-control study, Middle Aged, medicine.disease, Prognosis, Survival Analysis, nutrition, Endocrinology, medicine.anatomical_structure, Quartile, Oncology, Case-Control Studies, Female, medicine.symptom, Inflammation Mediators, business
Abstract

BACKGROUND: Macrophage inhibitory cytokine-1(MIC-1) is a potential modulator of systemic inflammation and nutritional depletion, both of which are adverse prognostic factors in oesophago-gastric cancer (OGC). METHODS: Plasma MIC-1, systemic inflammation (defined as plasma C-reactive protein (CRP) of >= 10 mg l(-1) or modified Glasgow prognostic score (mGPS) of >= 1),and nutritional status were assessed in newly diagnosed OGC patients (n = 293). Healthy volunteers (n = 35) served as controls. RESULTS: MIC-1 was elevated in patients (median 1371 pg ml(-1); range 141-39 053) when compared with controls (median 377 pg ml(-1); range 141-3786; P= 1 or plasma CRP of >= 10 mg l(-1) (median 9 mg l(-1); range 1-200). MIC-1 correlated positively with disease stage (r(2) = 0.217; P CONCLUSIONS: There is no independent link between plasma MIC-1 levels and depleted nutritional status or survival in OGC. British Journal of Cancer (2010) 102, 665-672. doi:10.1038/sj.bjc.6605532 www.bjcancer.com Published online 26 January 2010 (C) 2010 Cancer Research UK

Published
2010

49. Functional body composition and related aspects in research on obesity and cachexia:report on the 12th Stock Conference held on 6 and 7 September 2013 in Hamburg, Germany

Author

Müller, M J, Baracos, V, Bosy-Westphal, A, Dulloo, A G, Eckel, J, Fearon, K C H, Hall, K D, Pietrobelli, A, Sørensen, T I A, Speakman, J, Trayhurn, P, Visser, M, Heymsfield, S B, Müller, M J, Baracos, V, Bosy-Westphal, A, Dulloo, A G, Eckel, J, Fearon, K C H, Hall, K D, Pietrobelli, A, Sørensen, T I A, Speakman, J, Trayhurn, P, Visser, M, and Heymsfield, S B

Abstract

The 12th Stock Conference addressed body composition and related functions in two extreme situations, obesity and cancer cachexia. The concept of 'functional body composition' integrates body components into regulatory systems relating the mass of organs and tissues to corresponding in vivo functions and metabolic processes. This concept adds to an understanding of organ/tissue mass and function in the context of metabolic adaptations to weight change and disease. During weight gain and loss, there are associated changes in individual body components while the relationships between organ and tissue mass are fixed. Thus an understanding of body weight regulation involves an examination of the relationships between organs and tissues rather than individual organ and tissue masses only. The between organ/tissue mass relationships are associated with and explained by crosstalks between organs and tissues mediated by cytokines, hormones and metabolites that are coupled with changes in body weight, composition and function as observed in obesity and cancer cachexia. In addition to established roles in intermediary metabolism, cell function and inflammation, organ-tissue crosstalk mediators are determinants of body composition and its change with weight gain and loss. The 12th Stock Conference supported Michael Stocks' concept of gaining new insights by integrating research ideas from obesity and cancer cachexia. The conference presentations provide an in-depth understanding of body composition and metabolism.

Published
2014

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