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Taking logistics time, logistics cost, and carbon emissions as optimization objectives, air transportation is included in the cross-border logistics paths optimization of multimodal transportation. Considering the scale effect of transportation, a multiobjective optimization model of cross-border logistics paths including road, water, railway, and air is constructed. The problem of cross-border logistics paths along the “Belt and Road” regions for cities in inland is studied via the NSGA-II method. The research results show that Chengdu and Xi'an should bear a large number of cross-border air transportation and be constructed as the national airport-type logistics hub. The foreign destinations of cross-border air transportation are distributed in different regions, mainly in Eastern Europe and Eastern Central Europe. The optimization result shows that if there is a 1-fold increase in logistics cost, the logistics time can reduce by 1.37 folds after the cross-border air transportation joins in the model. Such a result has effectively guided the transition from cross-border water transportation to cross-border air transportation., Author(s): Feng-Jie Xie (corresponding author) [1]; Ruo-Chen Feng [1]; Xue-Yan Zhou [1] 1. Introduction The “Belt and Road” is a major national initiative for China's opening up. It aims to [...]

Context The prevalence of age-related cognitive decline has been on the rise as the global population age, putting the independence and quality of life of elderly at risk. Anthocyanin, as a subclass of dietary flavonoids, may have a beneficial impact on cognitive outcomes. Objectives To examine the effects of dietary anthocyanin supplementation on cognition of the cognitively healthy middle-aged and older adults. Data Sources PubMed, ScienceDirect, CINAHL, EMBASE, ProQuest and Cochrane databases were searched. Data Extraction and Analysis Thirteen studies were included in this meta-analysis. Anthocyanin-rich supplementation was found to significantly improve the processing speed of the older adults (95%CI 0.08, 0.44; P = 0.004). No significant differences were observed between intervention and control groups on memory, attention, executive function and psychomotor performance. Current neuroimaging studies have found promising effects of anthocyanin supplementation on brain activation and cerebral perfusion. Conclusion Anthocyanin-rich supplementation may preserve cognitive processing speed and neuro-activities in older adults, which improves their daily functioning and quality of life. This review provides useful insights to guide direction and methodological designs for future studies to explore the underlying mechanisms of anthocyanins. Systematic Review and Meta-analysis Registration PROSPERO registration No. CRD42021228007. [ABSTRACT FROM AUTHOR]