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Your search keyword '"Feng, Yechen"' showing total 21 results
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21 results on '"Feng, Yechen"'

1. Laparoscopic versus open surgery for perihilar cholangiocarcinoma: a multicenter propensity score analysis of short- term outcomes

Author

Wang, Min, Qin, Tingting, Zhang, Hang, Li, Jingdong, Deng, Xiaxing, Zhang, Yuhua, Zhao, Wenxing, Fan, Ying, Li, Dewei, Chen, Xuemin, Feng, Yechen, Zhu, Siwei, Xing, Zhongqiang, Yu, Guangsheng, Xu, Jian, Xie, Junjie, Dou, Changwei, Ma, Hongqin, Liu, Gangshan, Shao, Yue, Chen, Weibo, Liu, Jun, Liu, Jianhua, Yin, Xinmin, and Qin, Renyi

Published
2023
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2. The Long-Term Outcome of Laparoscopic Resection for Perihilar Cholangiocarcinoma Compared with the Open Approach: A Real-World Multicentric Analysis

Author

Qin, Tingting, Wang, Min, Zhang, Hang, Li, Jingdong, Deng, Xiaxing, Zhang, Yuhua, Zhao, Wenxing, Fan, Ying, Li, Dewei, Chen, Xuemin, Feng, Yechen, Zhu, Siwei, Xing, Zhongqiang, Yu, Guangsheng, Xu, Jian, Xie, Junjie, Dou, Changwei, Ma, Hongqin, Liu, Gangshan, Shao, Yue, Chen, Weibo, Xu, Simiao, Liu, Jun, Liu, Jianhua, Yin, Xinmin, and Qin, Renyi

Published
2023
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6. ASO Visual Abstract: The Long-Term Outcome of Laparoscopic Resection for Perihilar Cholangiocarcinoma Compared with the Open Approach: A Real-world, Multicentric Analysis

Author

Qin, Tingting, Wang, Min, Zhang, Hang, Li, Jingdong, Deng, Xiaxing, Zhang, Yuhua, Zhao, Wenxing, Fan, Ying, Li, Dewei, Chen, Xuemin, Feng, Yechen, Zhu, Siwei, Xing, Zhongqiang, Yu, Guangsheng, Xu, Jian, Xie, Junjie, Dou, Changwei, Ma, Hongqin, Liu, Gangshan, Shao, Yue, Chen, Weibo, Xu, Simiao, Liu, Jun, Liu, Jianhua, Yin, Xinmin, and Qin, Renyi

Published
2023
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8. supplemental material-Figure S3 from Blocking NF-κB Is Essential for the Immunotherapeutic Effect of Recombinant IL18 in Pancreatic Cancer

Author

Guo, Xingjun, primary, Zheng, Lei, primary, Jiang, Jianxin, primary, Zhao, Yan, primary, Wang, Xin, primary, Shen, Ming, primary, Zhu, Feng, primary, Tian, Rui, primary, Shi, Chengjian, primary, Xu, Meng, primary, Li, Xu, primary, Peng, Feng, primary, Zhang, Hang, primary, Feng, Yechen, primary, Xie, Yu, primary, Xu, Xiaodong, primary, Jia, Wei, primary, He, Ruizhi, primary, Xie, Chencheng, primary, Hu, Jun, primary, Ye, Dawei, primary, Wang, Min, primary, and Qin, Renyi, primary

Published
2023
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9. Supplemental Material and Methods from Blocking NF-κB Is Essential for the Immunotherapeutic Effect of Recombinant IL18 in Pancreatic Cancer

Author

Guo, Xingjun, primary, Zheng, Lei, primary, Jiang, Jianxin, primary, Zhao, Yan, primary, Wang, Xin, primary, Shen, Ming, primary, Zhu, Feng, primary, Tian, Rui, primary, Shi, Chengjian, primary, Xu, Meng, primary, Li, Xu, primary, Peng, Feng, primary, Zhang, Hang, primary, Feng, Yechen, primary, Xie, Yu, primary, Xu, Xiaodong, primary, Jia, Wei, primary, He, Ruizhi, primary, Xie, Chencheng, primary, Hu, Jun, primary, Ye, Dawei, primary, Wang, Min, primary, and Qin, Renyi, primary

Published
2023
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11. Additional file 1 of Laparoscopic versus open surgery for perihilar cholangiocarcinoma: a multicenter propensity score analysis of short- term outcomes

Author

Wang, Min, Qin, Tingting, Zhang, Hang, Li, Jingdong, Deng, Xiaxing, Zhang, Yuhua, Zhao, Wenxing, Fan, Ying, Li, Dewei, Chen, Xuemin, Feng, Yechen, Zhu, Siwei, Xing, Zhongqiang, Yu, Guangsheng, Xu, Jian, Xie, Junjie, Dou, Changwei, Ma, Hongqin, Liu, Gangshan, Shao, Yue, Chen, Weibo, Liu, Jun, Liu, Jianhua, Yin, Xinmin, and Qin, Renyi

Abstract

Additional file 1.

Published
2023
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15. Total laparoscopic pancreaticoduodenectomy versus open pancreaticoduodenectomy (TJDBPS01): study protocol for a multicentre, randomised controlled clinical trial

Author

Zhang, Hang, primary, Feng, Yechen, additional, Zhao, Junfang, additional, Chen, Rufu, additional, Chen, Xuemin, additional, Yin, Xinmin, additional, Cheng, Wei, additional, Li, Dewei, additional, Li, Jingdong, additional, Huang, Xiaobing, additional, Li, Jing, additional, Liu, Jianhua, additional, Liu, Jun, additional, Liu, Yahui, additional, Tan, Zhijian, additional, Zhao, Wenxing, additional, Huang, Heguang, additional, Li, Deyu, additional, Yu, Yahong, additional, Wang, Min, additional, and Qin, Renyi, additional

Published
2020
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18. New thoughts and techniques in pancreatic anastomosis

Author

FENG Yechen, WANG Min, and QIN Renyi

Subjects
lcsh:Diseases of the digestive system. Gastroenterology, lcsh:RC799-869
Abstract

The surgical procedures of pancreaticoduodenectomy are always controversial, and digestive tract reconstruction, especially the method of pancreatic anastomosis, has been one of the difficulties. This article introduces the methods of digestive tract reconstruction in pancreaticoduodenectomy at home and abroad and points out that the pancreas should be classified according to the size of pancreatic duct and the texture of the pancreas. The article puts forward the new “individualized” method of digestive tract reconstruction and instructs surgeons to select the appropriate surgical procedure to reduce the incidence of postoperative complications such as pancreatic fistula.

Published
2016

19. Blocking NF-κB Is Essential for the Immunotherapeutic Effect of Recombinant IL18 in Pancreatic Cancer

Author

Guo, Xingjun, primary, Zheng, Lei, additional, Jiang, Jianxin, additional, Zhao, Yan, additional, Wang, Xin, additional, Shen, Ming, additional, Zhu, Feng, additional, Tian, Rui, additional, Shi, Chengjian, additional, Xu, Meng, additional, Li, Xu, additional, Peng, Feng, additional, Zhang, Hang, additional, Feng, Yechen, additional, Xie, Yu, additional, Xu, Xiaodong, additional, Jia, Wei, additional, He, Ruizhi, additional, Xie, Chencheng, additional, Hu, Jun, additional, Ye, Dawei, additional, Wang, Min, additional, and Qin, Renyi, additional

Published
2016
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20. Par3 regulates invasion of pancreatic cancer cells via interaction with Tiam1

Author

Guo, Xingjun, primary, Wang, Min, additional, Zhao, Yan, additional, Wang, Xin, additional, Shen, Ming, additional, Zhu, Feng, additional, Shi, Chengjian, additional, Xu, Meng, additional, Li, Xu, additional, Peng, Feng, additional, Zhang, Hang, additional, Feng, Yechen, additional, Xie, Yu, additional, Xu, Xiaodong, additional, Jia, Wei, additional, He, Ruizhi, additional, Jiang, Jianxin, additional, Hu, Jun, additional, Tian, Rui, additional, and Qin, Renyi, additional

Published
2015
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21. Upregulation of METTL14 mediates the elevation of PERP mRNA N6 adenosine methylation promoting the growth and metastasis of pancreatic cancer.

Author

Wang, Min, Liu, Jun, Zhao, Yan, He, Ruizhi, Xu, Xiaodong, Guo, Xingjun, Li, Xu, Xu, Simiao, Miao, Ji, Guo, Jianpin, Zhang, Hang, Gong, Jun, Zhu, Feng, Tian, Rui, Shi, Chengjian, Peng, Feng, Feng, Yechen, Yu, Shuo, Xie, Yu, and Jiang, Jianxin

Subjects
ADENOSINES, PANCREATIC cancer, METASTASIS, CANCER cell proliferation, CANCER cell migration, MESSENGER RNA
Abstract

Background: Pancreatic cancer is one of the most lethal human cancers. N6-methyladenosine (m6A), a common eukaryotic mRNA modification, plays critical roles in both physiological and pathological processes. However, its role in pancreatic cancer remains elusive. Methods: LC/MS was used to profile m6A levels in pancreatic cancer and normal tissues. Bioinformatics analysis, real-time PCR, immunohistochemistry, and western blotting were used to identify the role of m6A regulators in pancreatic cancer. The biological effects of methyltransferase-like 14 (METTL14), an mRNA methylase, were investigated using in vitro and in vivo models. MeRIP-Seq and RNA-Seq were used to assess the downstream targets of METTL14. Results: We found that the m6A levels were elevated in approximately 70% of the pancreatic cancer samples. Furthermore, we demonstrated that METTL14 is the major enzyme that modulates m6A methylation (frequency and site of methylation). METTL14 overexpression markedly promoted pancreatic cancer cell proliferation and migration both in vitro and in vivo, via direct targeting of the downstream PERP mRNA (p53 effector related to PMP-22) in an m6A-dependent manner. Methylation of the target adenosine lead to increased PERP mRNA turnover, thus decreasing PERP (mRNA and protein) levels in pancreatic cancer cells. Conclusions: Our data suggest that the upregulation of METTL14 leads to the decrease of PERP levels via m6A modification, promoting the growth and metastasis of pancreatic cancer; therefore METTL14 is a potential therapeutic target for its treatment. [ABSTRACT FROM AUTHOR]

Published
2020
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