Search

Your search keyword '"Fergus Keating"' showing total 4 results
Start Over Author "Fergus Keating"
4 results on '"Fergus Keating"'

1. Hybrid immunity in older adults is associated with reduced SARS-CoV-2 infections following BNT162b2 COVID-19 immunisation

Author

Scott J. C. Pallett, Joseph Heskin, Fergus Keating, Andrea Mazzella, Hannah Taylor, Aatish Patel, Georgia Lamb, Deborah Sturdy, Natalie Eisler, Sarah Denny, Esmita Charani, Paul Randell, Nabeela Mughal, Eleanor Parker, Carolina Rosadas de Oliveira, Michael Rayment, Rachael Jones, Richard Tedder, Myra McClure, Elisabetta Groppelli, Gary W. Davies, Matthew K. O’Shea, and Luke S. P. Moore

Subjects
Medicine
Abstract

Abstract Background Older adults, particularly in long-term care facilities (LTCF), remain at considerable risk from SARS-CoV-2. Data on the protective effect and mechanisms of hybrid immunity are skewed towards young adults precluding targeted vaccination strategies. Methods A single-centre longitudinal seroprevalence vaccine response study was conducted with 280 LCTF participants (median 82 yrs, IQR 76-88 yrs; 95.4% male). Screening by SARS-CoV-2 polymerase chain reaction with weekly asymptomatic/symptomatic testing (March 2020-October 2021) and serology pre-/post-two-dose Pfizer-BioNTech BNT162b2 vaccination for (i) anti-nucleocapsid, (ii) quantified anti-receptor binding domain (RBD) antibodies at three time-intervals, (iii) pseudovirus neutralisation, and (iv) inhibition by anti-RBD competitive ELISA were conducted. Neutralisation activity: antibody titre relationship was assessed via beta linear-log regression and RBD antibody-binding inhibition: post-vaccine infection relationship by Wilcoxon rank sum test. Results Here we show neutralising antibody titres are 9.2-fold (95% CI 5.8–14.5) higher associated with hybrid immunity (p 100BAU/ml), show inhibition

Published
2023
Full Text
View/download PDF

4. The Use of Rhyme and Orthography in a Cued Recall Task: A Comparison of Different Age and Ability Groups

Author

Stanton Newman, Heather Fields, Fergus Keating, and Sarah Wright

Subjects
Cued recall, Communication, Recall, business.industry, Rhyme, media_common.quotation_subject, Judgement, Code (semiotics), Task (project management), Reading (process), Psychology, business, General Psychology, Orthography, Cognitive psychology, media_common
Abstract

A cued recall task was used to determine whether three groups of age-matched children at different reading levels and two groups of skilled, adult readers would show differences in their use of the phonological and orthographic code in memory. Poor readers were significantly slower in a rhyme judgement task, made more errors in detecting rhyme and recalled fewer target cue pairs. These findings support the view that poor readers have less easy access to a phonological code in memory and poorer overall memory, However, no differences were found between any of the groups in their pattern of recall across particular target-cue pairs. Poor readers were not found to make increased use of the orthographic code.

Published
1989

Catalog

Books, media, physical & digital resources
See catalog results