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170 results on '"Ferguson, N. M."'

17. Author Correction: SARS-CoV-2 antibody dynamics and transmission from community-wide serological testing in the Italian municipality of Vo’ (Nature Communications, (2021), 12, 1, (4383), 10.1038/s41467-021-24622-7)

Author

Dorigatti, I., Lavezzo, E., Manuto, L., Ciavarella, C., Pacenti, M., Boldrin, C., Cattai, M., Saluzzo, F., Franchin, E., Del Vecchio, C., Caldart, F., Castelli, G., Nicoletti, M., Nieddu, E., Salvadoretti, E., Labella, B., Fava, L., Guglielmo, S., Fascina, M., Grazioli, M., Alvisi, G., Vanuzzo, M. C., Zupo, T., Calandrin, R., Lisi, V., Rossi, L., Castagliuolo, I., Merigliano, S., Unwin, H. J. T., Plebani, M., Padoan, A., Brazzale, A. R., Toppo, S., Ferguson, N. M., Donnelly, C. A., and Crisanti, A.

Published
2021

18. Author Correction: Suppression of a SARS-CoV-2 outbreak in the Italian municipality of Vo’ (Nature, (2020), 584, 7821, (425-429), 10.1038/s41586-020-2488-1)

Author

Lavezzo, E., Franchin, E., Ciavarella, C., Cuomo-Dannenburg, G., Barzon, L., Del Vecchio, C., Rossi, L., Manganelli, R., Loregian, A., Navarin, N., Abate, D., Sciro, M., Merigliano, S., De Canale, E., Vanuzzo, M. C., Besutti, V., Saluzzo, F., Onelia, F., Pacenti, M., Parisi, S. G., Carretta, G., Donato, D., Flor, L., Cocchio, S., Masi, G., Sperduti, A., Cattarino, L., Salvador, R., Nicoletti, M., Caldart, F., Castelli, G., Nieddu, E., Labella, B., Fava, L., Drigo, M., Gaythorpe, K. A. M., Ainslie, K. E. C., Baguelin, M., Bhatt, S., Boonyasiri, A., Boyd, O., Coupland, H. L., Cucunuba, Z., Djafaara, B. A., van Elsland, S. L., Fitzjohn, R., Flaxman, S., Green, W. D., Hallett, T., Hamlet, A., Haw, D., Imai, N., Jeffrey, B., Knock, E., Laydon, D. J., Mellan, T., Mishra, S., Nedjati-Gilani, G., Nouvellet, P., Okell, L. C., Parag, K. V., Riley, S., Thompson, H. A., Unwin, H. J. T., Verity, R., Vollmer, M. A. C., Walker, P. G. T., Walters, C. E., Wang, H., Wang, Y., Watson, O. J., Whittaker, C., Whittles, L. K., Xi, X., Brazzale, A. R., Toppo, S., Trevisan, M., Baldo, V., Donnelly, C. A., Ferguson, N. M., Dorigatti, I., and Crisanti, A.

Published
2021

24. Transmission dynamics and epidemiology of BSE in British cattle

Author

Anderson, R. M., Donnelly, C. A., Ferguson, N. M., Woolhouse, M. E. J., Watt, C. J., Udy, H. J., MaWhinney, S., Dunstan, S. P., Southwood, T. R. E., Wilesmith, J. W., Ryan, J. B. M., Hoinville, L. J., Hillerton, J. E., Austin, A. R., and Wells, G. A. H.

Published
1996

26. Surrogate markers for disease progression in treated HIV infection

Author

Ghani, A. C., de Wolf, F., Ferguson, N. M., Donnelly, C. A., Coutinho, R., Miedema, F., Goudsmit, J., Anderson, R. M., and Other departments

Subjects
virus diseases
Abstract

To characterize the relationships among highly active antiretroviral therapy (HAART), HIV-1 RNA levels, immune system markers, and clinical outcome in a cohort of HIV-1-infected homosexual men. A total of 123 men enrolled in the Amsterdam cohort study of HIV-1 infection and AIDS with a documented seroconversion for HIV-1 antibodies and known date of seroconversion were included in this study. CD4 + /CD8 + T-cell counts and HIV-1 RNA levels in plasma were measured approximately every 6 months. Dates of starting and stopping antiretroviral therapy were also recorded. The relationship between HIV-1 RNA in plasma, CD4 + /CD8 + T-cell counts and HAART and their influence on clinical outcome were examined using a graphical chain modeling approach. Generalized estimating equations were used to examine correlations among the three disease markers. Hazards models with time-dependent covariates were used to examine the influence of HAART and the disease markers on progression to AIDS. HAART was significantly associated with reduced disease progression (relative hazard [RH] of AIDS, 0.20;, 95% confidence interval [CI], 0.05-0.85). The most recent HIV-1 RNA measurement and CD4 + T-cell count are independently associated with disease progression (adjusted RH for HIV-1 RNA 1.8 per log 10 increase; 95% CI, 1.2-2.6, p =.002; adjusted RH for CD4 + 0.48 per 100 x 10(6)/L increase; 95% CI, 0.40-0.58; p

Published
2001

38. Correction: Transmission dynamics and epidemiology of BSE in British cattle

Author

Anderson, R. M., primary, Donnelly, C. A., additional, Ferguson, N. M., additional, Woolhouse, M. E. J., additional, Watt, C. J., additional, Udy, H. J., additional, MaWhinney, S., additional, Dunstan, S. P., additional, Southwood, T. R. E., additional, Wilesmith, J. W., additional, Ryan, J. B. M., additional, Hoinville, L. J., additional, Hillerton, J. E., additional, Austin, A. R., additional, and Wells, G. A. H., additional

Published
1997
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43. Dynamics of a scrapie outbreak in a flock of Romanov sheep – estimation of transmission parameters

Author

HAGENAARS, T. J., DONNELLY, C. A., FERGUSON, N. M., and ANDERSON, R. M.

Abstract

Knowledge of epidemiological mechanisms and parameters underlying scrapie transmission in sheep flocks remains very limited at present. Here we introduce a method for fitting stochastic transmission models to outbreak data to estimate bounds on key transmission parameters. We apply this method to data describing an outbreak of scrapie in a closed flock of Romanov sheep. The main findings are that the relative infectiousness of infected animals in this outbreak becomes appreciable early into disease incubation and that the mean incubation period is less than 1·5 years. We also find that the data are consistent with a broad range of values for the basic reproduction number R0 and describe how the boundaries of this range depend on assumptions about the mean incubation period and the contribution to transmission of a long-lived environmental reservoir of infectivity.

Published
2003

44. Persistence patterns of scrapie in a sheep flock

Author

*, T. J. HAGENAARS, †, FERGUSON, N. M., DONNELLY, C. A., and ANDERSON, R. M.

Abstract

The epidemiology and transmission dynamics of sheep scrapie is as yet poorly understood. Here we present a theoretical analysis of the transmission dynamics within a sheep flock, concentrating on how persistence properties depend on transmission scenario and flock size. Patterns of disease persistence and extinction are studied analytically using branching-process approximations and numerically using stochastic model simulations. For a given basic reproduction number, disease extinction is most likely when late-stage infected animals are responsible for most of the transmission. This effect can be understood in terms of aggregation in the distribution of the number of secondary infections arising from a single primary infection. The presence of an environmental reservoir reduces the probability of extinction.

Published
2001

47. State of knowledge and data gaps of middle east respiratory syndrome coronavirus (MERS-CoV) in humans

Author

Abdallat, M. M., Abroug, F., Al Dhahry, S. H. S., Alhajri, M. M., Al-Hakeem, R., Al Hosani, F. I., Al Qasrawi, S. M. A., Al-Romaihi, H. E., Assiri, A., Baillie, J. K., Ben Embarek, P. K., Ben Salah, A., Blümel, B., Briese, T., Buchholz, U., Cognat, S. B. F., Defang, G. N., La Rocque, S., Donatelli, I., Drosten, C., Drury, P. A., Eremin, S. R., Ferguson, N. M., Fontanet, A., Formenty, P. B. H., Fouchier, R. A. M., Gao, C. Q., Garcia, E., Gerber, S. I., Guery, B., Haagmans, B. L., Haddadin, A. J., Hardiman, M. C., Lisa Hensley, Hugonnet, S. A. L., Hui, D. S. C., Isla, N., Karesh, W. B., Koopmans, M., Kuehne, A., Lipkin, W. I., Mafi, A. R., Malik, M., Manuguerra, J. -C, Memish, Z., Mounts, A. W., Mumford, E., Opoka, L., Osterhaus, A., John Oxenford, C., Pang, J., Pebody, R., Peiris, J. S. M., Jay Plotkin, B., Poumerol, G., Reusken, C., Rezza, G., Roth, C. E., Shindo, N., Shumate, A. M., Siwula, M., Slim, A., Smallwood, C., Werf, S., Kerkhove, M. D., and Zambon, M.

48. Influenza: Making Privileged Data Public Response

Author

Christophe Fraser, Donnelly, C. A., Cauchemez, S., Hanage, W. P., Kerkhove, M. D., Hollingsworth, T. D., Griffin, J., Baggaley, R. F., Jenkins, H. E., Lyons, E. J., Jombart, T., Hinsley, W. R., Grassly, N. C., Balloux, F., Ghani, A. C., Rambaut, A., and Ferguson, N. M.

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