216 results on '"Ferla, Salvatore"'
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2. Insights into E. coli cyclopropane fatty acid synthase (CFAS) towards enantioselective carbene free biocatalytic cyclopropanation.
3. Anti-schistosomal activities of quinoxaline-containing compounds: From hit identification to lead optimisation
4. Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents
5. A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents
6. Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors
7. Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors
8. A new series of bicalutamide, enzalutamide and enobosarm derivatives carrying pentafluorosulfanyl (SF5) and pentafluoroethyl (C2F5) substituents: Improved antiproliferative agents against prostate cancer
9. Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni
10. Small molecule inhibitors of CYP24A1 for the treatment of various cancers
11. Synthesis and biological evaluation of 6-substituted-5-fluorouridine ProTides
12. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition
13. Discovery of novel multi-target indole-based derivatives as potent and selective inhibitors of chikungunya virus replication
14. A new antiviral scaffold for human norovirus identified with computer-aided approaches on the viral polymerase
15. Handheld Raman Spectroscopy in the First UK Home Office Licensed Pharmacist-Led Community Drug Checking Service
16. Biocatalytic and Chemo-Enzymatic Synthesis of Quinolines and 2-Quinolones by Monoamine Oxidase (MAO-N) and Horseradish Peroxidase (HRP) Biocatalysts
17. Design and synthesis of novel bicalutamide and enzalutamide derivatives as antiproliferative agents for the treatment of prostate cancer
18. Quercetin derivatives as novel antihypertensive agents: Synthesis and physiological characterization
19. Structural Investigations on Novel Non-Nucleoside Inhibitors of Human Norovirus Polymerase
20. Ligand-based discovery of a novel GATA2 inhibitor targeting acute myeloid leukemia cells
21. Novel styryl-indoles as small molecule inhibitors of 25-hydroxyvitamin D-24-hydroxylase (CYP24A1): Synthesis and biological evaluation
22. Design, Synthesis and Biological Investigation of 2-Anilino Triazolopyrimidines as Tubulin Polymerization Inhibitors with Anticancer Activities
23. A Composite System Based upon Hydroxypropyl Cyclodextrins and Soft Hydrogel Contact Lenses for the Delivery of Therapeutic Doses of Econazole to the Cornea, In Vitro
24. Broad-spectrum non-nucleoside inhibitors for caliciviruses
25. Synthesis and Biological Evaluation of Highly Active 7-Anilino Triazolopyrimidines as Potent Antimicrotubule Agents
26. Structural Investigations on Novel Non-Nucleoside Inhibitors of Human Norovirus Polymerase.
27. Structure–Activity Relationship Studies on Novel Antiviral Agents for Norovirus Infections
28. Polyfluorinated groups in medicinal chemistry
29. Rational design of highly potent broad-spectrum enterovirus inhibitors targeting the nonstructural protein 2C
30. Targeting the Complement Serine Protease MASP-2 as a Therapeutic Strategy for Coronavirus Infections
31. Synthesis and biological evaluation of new antitubulin agents containing 2-(30,40,50-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold
32. Computational Studies towards the Identification of Novel Rhodopsin-Binding Compounds as Chemical Chaperones for Misfolded Opsins
33. Successful subthalamic stimulation in genetic Parkinson’s disease caused by duplication of the α-synuclein gene
34. Synthesis and antiviral effect of novel fluoxetine analogues as enterovirus 2C inhibitors
35. Monoamine Oxidase (MAO-N) Biocatalyzed Synthesis of Indoles from Indolines Prepared via Photocatalytic Cyclization/Arylative Dearomatization
36. Synthesis and Biological Evaluation of 2-Substituted Benzyl-/Phenylethylamino-4-amino-5-aroylthiazoles as Apoptosis-Inducing Anticancer Agents
37. Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3′,4′,5′-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold
38. Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization
39. Rational modifications, synthesis and biological evaluation of new potential antivirals for RSV designed to target the M2-1 protein
40. Suramin Inhibits Chikungunya Virus Replication by Interacting with Virions and Blocking the Early Steps of Infection
41. The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets
42. Growth factor (M-CSF) and antigenic properties of macrophages in meningioma
43. Structure-activity relationship study of itraconazole, a broad-range inhibitor of picornavirus replication that targets oxysterol-binding protein (OSBP)
44. Erratum to ‘Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni’ [IJP Drugs Drug Resist. 8 (2018) 559–570]
45. A novel interaction between dengue virus nonstructural protein 1 and the NS4A-2K-4B precursor is required for viral RNA replication but not for formation of the membranous replication organelle
46. Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2-d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors
47. 3-Aryl/Heteroaryl-5-amino-1-(3′,4′,5′-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization
48. Rational design and synthesis of novel phenylsulfonyl-benzamides as anti-prostate cancer agents
49. Rational design and synthesis of novel anti-prostate cancer agents bearing a 3,5-bis-trifluoromethylphenyl moiety
50. Development of a new calcilytic for the treatment of inflammatory lung disease
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