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5. Personalized cardiovascular risk assessment in Rheumatoid Arthritis patients using circulating molecular profiles and their modulation by TNFi, IL6Ri, and JAKinibs

Author

Muñoz-Barrera, Laura, Perez-Sanchez, Carlos, Ortega-Castro, Rafaela, Corrales, Sagrario, Luque-Tevar, Maria, Cerdó, Tomás, Sanchez-Pareja, Ismael, Font, Pilar, Lopez-Mejías, Raquel, Calvo, Jerusalem, Abalos-Aguilera, M.Carmen, Ruiz-Vilchez, Desiree, Segui, Pedro, Merlo, Christian, Perez-Venegas, José, Ruiz Montesino, Ma Dolores, Rodriguez- Escalera, Carlos, Barco, Carmen Romero, Fernandez-Nebro, Antonio, Vazque, Natalia Mena, Marenco, Jose Luis, Montañes, Julia Uceda, Godoy-Navarrete, Javier, Cabezas-Lucena, Alba Ma, Estevez, Eduardo Collantes, Aguirre, Ma Angeles, González-Gay, Miguel A., Barbarroja, Nuria, Escudero-Contreras, Alejandro, and Lopez-Pedrera, Chary

Published
2024
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6. Use of risk chart algorithms for the identification of psoriatic arthritis patients at high risk for cardiovascular disease: findings derived from the project CARMA cohort after a 7.5-year follow-up period

Author

Jesús Tornero, Alba Erra, Santos Castañeda, Carolina Pérez-García, Raimon Sanmartí, Sara Marsal, Ingrid Moller, Esperanza Naredo, Miguel A González-Gay, Celia Erausquin, Ivan Castellví, Javier Llorca, Alejandro Muñoz, María Galindo, Enrique Raya, Lydia Abasolo, Gema Bonilla, Alfonso Corrales, Inmaculada Ureña, Carlos Rodríguez-Lozano, Carlos González-Juanatey, Cristina Fernandez Carballido, Francisco J López-Longo, Miguel Ángel González-Gay, Eduardo Collantes, José A Miranda-Filloy, Sagrario Bustabad, Indalecio Monteagudo, Jose A Piqueras, Tatiana Cobo, Joan Maymó, Carmen Barbadillo, Soledad Ojeda, Jaime Calvo Alen, Antonio Fernandez Nebro, Isabel Rodríguez, Pilar Font, Martina Steiner, Eugenio Chamizo Carmona, Beatriz González Álvarez, Santiago Munoz, Joan M Nolla, Fernando Sánchez-Alonso, Julio Sanchez, Raul Menor Almagro, Ana Pérez Gómez, Monica Ibañez, Elena Heras-Recuero, Trinidad Pérez Sandoval, Miren Uriarte-Ecenarro, Angela Pecondón, Hye Sang Park, Jessica Polo y La Borda, Zulema Plaza, Carmen García Gómez, Ivan Ferraz-Amaro, Jesús Tomás Sanchez-Costa, Olga Carmen Sánchez-González, Ana Isabel Turrión-Nieves, Ana Perez-Alcalá, José L FernándezSueiro, José A Pinto-Tasende, Eugenia Gonzálezde Rábago, María J González-Fernández, Ramón Huguet Codina, Beatriz Yoldi, Mercedes Ramentol, Gabriela Ávila, Cayetano Alegre, Fernando Gamero, José García Torón, María P Moreno-Gil, Antonio Juan-Mas, Pilar Espiño, Inmaculada Ros, Horacio Berman, Oscar Fontseré Patón, Benjamín Fernández Gutiérrez, José M Pina-Salvador, María D Fábregas, Montserrat Romera, Jesús A García-Vadillo, Rosario García de Vicuña, María A Belmonte, María V Irigoyen, Olga Martínez González, Rebeca Belmonte Gómez, Pastora Granados Bautista, Azucena Hernández Sanz, José Santos Rey, Carmen O Sánchez-González, Javier Bachiller, Antonio Zea, Francisco J Manero, Chesús Beltrán Audera, Marta Medrano, Jesús Babío Herráez, Javier del Pino, Ruth López González, María Enriqueta Peiró, José M Senabre, José C Rosas, Isabel Rotés, Estefanía Moreno, Javier Calvo, Amalia Rueda, Pilar Morales, Ana Nieto, Ana Ruibal Escribano, Sergio Ros Expósito, Ginés Sánchez Nievas, Enrique Júdez Navarro, Manuela Sianes Fernández, Silvia Martínez Pardo, Manel Pujol, Alberto Cantabrana, Esmeralda Delgado, Sergio Rodríguez Montero, Javier Rivera Redondo, Teresa González Hernández, Francisco J González-Polo, José M Moreno, Emilio Giner Serret, Laura Cebrián Méndez, María Teresa Navío, Teresa Pedraz Penalva, Encarnación Pagán, Pablo Mesadel Castillo, Ana Cruz, Ana Turrión, Desireé Ruíz, Antonio López Meseguer, Manuel J Moreno, Luis F Linares, Mercedes Morcillo, María L González-Gómez, José M Aramburu, Natalia A Rivera, Olaia Fernández Berrizbeitia, Manel Riera, Yolanda María León, Miriam Amirall, Jordi Fiter, Julia Fernández Melón, Luis Espadaler, Joaquín Belzunegui, Inmaculada Bañegil, César Díaz, Ramón Valls, María Bonet, Eva Revuelta Evrard, Javier R Godo, and José A González-Fernández

Subjects
Medicine
Abstract

Objective To assess the predictive value of four cardiovascular (CV) risk algorithms for identifying high-risk psoriatic arthritis (PsA) patients.Methods Evaluation of patients with PsA enrolled in the Spanish prospective project CARdiovascular in RheuMAtology. Baseline data of 669 PsA patients with no history of CV events at the baseline visit, who were followed in rheumatology outpatient clinics at tertiary centres for 7.5 years, were retrospectively analysed to test the performance of the Systematic Coronary Risk Assessment (SCORE), the modified version (mSCORE) European Alliance of Rheumatology Associations (EULAR) 2015/2016, the SCORE2 algorithm (the updated and improved version of SCORE) and the QRESEARCH risk estimator version 3 (QRISK3).Results Over 4790 years of follow-up, there were 34 CV events, resulting in a linearised rate of 7.10 per 1000 person-years (95% CI 4.92 to 9.92). The four CV risk scales showed strong correlations and all showed significant associations with CV events (p

Published
2024
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8. Analysis of comorbidity in rheumatoid arthritis–associated interstitial lung disease: a nested case-cohort study

Author

Mena-Vázquez, Natalia, Rojas-Gimenez, Marta, Romero-Barco, Carmen María, Gandía-Martínez, Myriam, Perez-Gómez, Nair, Godoy-Navarrete, Francisco Javier, Manrique-Arija, Sara, Garcia-Studer, Aimara, Calvo-Gutiérrez, Jerusalem, Varela, Clara Fuego, Morales-Garrido, Pilar, Pérez, Patricia Castro, Mouriño-Rodriguez, Coral, Añón-Oñate, Isabel, Espildora, Francisco, Aguilar-Hurtado, María Carmen, Redondo, Rocío, Conde, Ana Hidalgo, de los Ríos, Rocío Arnedo Díez, César, Eva Cabrera, Velloso-Feijoo, Maria Luisa, and Fernández-Nebro, Antonio

Published
2023
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9. Effectiveness and safety of tocilizumab in monotherapy in biologic-naïve and non-naïve patients with rheumatoid arthritis in a real-world setting

Author

Marsal Barril, Sara, Martin-Martinez, Mª Auxiliadora, Blanco-Garcia, Francisco Javier, Fernández-Nebro, Antonio, García de Vicuña, Rosario, Tornero-Molina, Jesús, Sánchez-Alonso, Fernando, Novella-Navarro, Marta, Escudero-Contreras, Alejandro, Alegre-Sancho, Juan José, Urruticoechea-Arana, Ana, Bustabad-Reyes, Maria Sagrario, Trenor-Larraz, Pilar, Pérez-Sandoval, Trinidad, Tevar-Sánchez, Maria Isabel, Sánchez-Costa, Jesús T., and Raya-Álvarez, Enrique

Published
2022
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14. Hospitalizaciones y mortalidad por COVID-19 en pacientes con enfermedades inflamatorias reumáticas en Andalucía

Author

Mena-Vázquez, Natalia, Manrique Arija, Sara, Rojas-Giménez, Marta, Raya-Álvarez, Enrique, Velloso-Feijoó, María Luisa, López-Medina, C., Ramos-Giraldez, Consuelo, Godoy-Navarrete, Francisco Javier, Redondo-Rodríguez, Rocío, Cabezas-Lucena, Alba María, Morales-Águila, M., Romero-Barco, C.M., and Fernández-Nebro, Antonio

Published
2022
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15. Longitudinal analysis of blood DNA methylation identifies mechanisms of response to tumor necrosis factor inhibitor therapy in rheumatoid arthritis

Author

Julià, Antonio, Gómez, Antonio, López-Lasanta, María, Blanco, Francisco, Erra, Alba, Fernández-Nebro, Antonio, Mas, Antonio Juan, Pérez-García, Carolina, Vivar, Ma Luz García, Sánchez-Fernández, Simón, Alperi-López, Mercedes, Sanmartí, Raimon, Ortiz, Ana María, Fernandez-Cid, Carlos Marras, Díaz-Torné, César, Moreno, Estefania, Li, Tianlu, Martínez-Mateu, Sergio H., Absher, Devin M., Myers, Richard M., Molina, Jesús Tornero, and Marsal, Sara

Published
2022
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16. Antimalarials exert a cardioprotective effect in lupus patients: Insights from the Spanish Society of Rheumatology Lupus Register (RELESSER) analysis of factors associated with heart failure

Author

Rúa-Figueroa, Iñigo, Rúa-Figueroa, David, Pérez-Veiga, Natalia, Anzola, Ana M., Galindo-Izquierdo, María, Calvo-Alén, Jaime, Fernández-Nebro, Antonio, Sangüesa, Clara, Menor-Almagro, Raúl, Tomero, Eva, del Val, Natividad, Uriarte-Isazelaya, Esther, Blanco, Ricardo, Andreu, José L., Boteanu, Alina, Narváez, Javier, Cobo, Tatiana, Bohórquez, Cristina, Montilla, Carlos, Salas, Esteban, Toyos, Francisco J., Bernal, José A., Salgado, Eva, Freire, Mercedes, Mas, Antonio J., Expósito, Lorena, Hernández-Beriain, José A., Ibarguengoitia, Oihane, Velloso-Feijoo, María L., Lozano-Rivas, Nuria, Bonilla, Gemma, Moreno, Mireia, Jiménez, Inmaculada, Quevedo-Vila, Víctor, Pecondón, Angela, Aurrecoechea, Elena, Valls, Elia, Mouriño, Coral, Vázquez-Rodríguez, Tomás, and Pego-Reigosa, José M.

Published
2022
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19. Contributions of the lupus register of the Spanish Society of Rheumatology (RELESSER) to the knowledge of systemic lupus erythematosus in Spain

Author

López-Longo, J., Galindo-Izquierdo, M., Calvo-Alén, J., del Campo, V., Olivé-Marqués, A., Pérez-Vicente, S., Fernández-Nebro, A., Andrés, M., Erausquin, C., Tomero, E., Horcada, L., Uriarte, E., Freire, M., Montilla, C., Sánchez-Atrio, A., Santos, G., Boteanu, A., Díez-Álvarez, E., Narváez, J., Blanco-Alonso, R., Martínez-Taboada, V., Silva-Fernández, L., Ruiz-Lucea, E., Andreu, J.L., Hernández-Beriain, J.Á., Gantes, M., Hernández-Cruz, B., Pérez-Venegas, J., Rodríguez-Gómez, M., Zea, A., Fernández-Castro, M., Pecondón-Español, Á., Marras, C., Ibáñez-Barceló, M., Bonilla, G., Torrente-Segarra, V., Castellví, I., Alegre, J.J., Calvet, J., Marenco, J.L., Raya, E., Vázquez, T., Quevedo, V., Muñoz-Fernández, S., Ibáñez, J., Fernández-Berrizbeitia, O., Expósito, L., Carreira, P., Moreno, M., de la Peña, P.G., Aguirre, M.Á., Salman-Monte, T.C., Riveros Frutos, A., Tejera, B., Cobo-Ibañez, T., Sánchez-Alonso, F., Melero-González, R., Otón-Sánchez, T., García-Yebenes, M.J., Menor-Almagro, R., Mouriño, C., Fito-Manteca, C., Galisteo, C., Manero, J., Lois-Iglesias, A., Valls-Pascual, E., Manrique-Arija, S., Ucar, E., Borrell, H., Salgado, E., Rúa-Figueroa Fernández de Larrinoa, Iñigo, and Pego-Reigosa, José María

Published
2021
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20. Aportaciones del registro de lupus de la Sociedad Española de Reumatología (RELESSER) al conocimiento del lupus eritematoso sistémico en España

Author

López-Longo, J., Galindo-Izquierdo, M., Calvo-Alén, J., del Campo, V., Olivé-Marqués, A., Pérez-Vicente, S., Fernández-Nebro, A., Andrés, M., Erausquin, C., Tomero, E., Horcada, L., Uriarte, E., Freire, M., Montilla, C., Sánchez-Atrio, A., Santos, G., Boteanu, A., Díez-Álvarez, E., Narváez, J., Blanco-Alonso, R., Martínez-Taboada, V., Silva-Fernández, L., Ruiz-Lucea, E., Andreu, J.L., Hernández-Beriain, J.Á., Gantes, M., Hernández-Cruz, B., Pérez-Venegas, J., Rodríguez-Gómez, M., Zea, A., Fernández-Castro, M., Pecondón-Español, Á., Marras, C., Ibáñez-Barceló, M., Bonilla, G., Torrente-Segarra, V., Castellví, I., Alegre, J.J., Calvet, J., Marenco, J.L., Raya, E., Vázquez, T., Quevedo, V., Muñoz-Fernández, S., Ibáñez, J., Fernández-Berrizbeitia, O., Expósito, L., Carreira, P., Moreno, M., de la Peña, P.G., Aguirre, M.Á., Salman-Monte, T.C., Riveros Frutos, A., Tejera, B., Cobo-Ibañez, T., Sánchez-Alonso, F., Melero-González, R., Otón-Sánchez, T., García-Yebenes, M.J., Menor-Almagro, R., Mouriño, C., Fito-Manteca, C., Galisteo, C., Manero, J., Lois-Iglesias, A., Valls-Pascual, E., Manrique-Arija, S., Ucar, E., Borrell, H., Salgado, E., Rúa-Figueroa Fernández de Larrinoa, Iñigo, and Pego-Reigosa, José María

Published
2021
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29. Prevalence of Comorbidities in Rheumatoid Arthritis and Evaluation of Their Monitoring in Clinical Practice: The Spanish Cohort of the COMORA Study

Author

Balsa, Alejandro, Lojo-Oliveira, Leticia, Alperi-López, Mercedes, García-Manrique, María, Ordóñez-Cañizares, Carmen, Pérez, Lorena, Ruiz-Esquide, Virginia, Corrales, Alfonso, Narváez, Javier, Rey-Rey, José, Rodríguez-Lozano, Carlos, Ojeda, Soledad, Muñoz-Fernández, Santiago, Nolla, Joan M., García-Torrón, José, Gamero, Fernando, García-Vicuña, Rosario, Hernández-Cruz, Blanca, Campos, José, Rosas, José, García-Llorente, José Francisco, Gómez-Centeno, Antonio, Cáliz, Rafael, Sanmartí, Raimon, Bermúdez, Alberto, Abasolo-Alcázar, Lydia, Fernández-Nebro, Antonio, Rodríguez-Rodríguez, Luis, Marras, Carlos, González-Gay, Miguel Ángel, Hmamouchi, Ihsane, and Martín-Mola, Emilio

Published
2019
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30. Damage in a large systemic lupus erythematosus cohort from the Spanish Society of Rheumatology Lupus Registry (RELESSER) with emphasis on the cardiovascular system: a longitudinal analysis.

Author

Altabás-González, Irene, Rua-Figueroa, Iñigo, Mouriño, Coral, Roberts, Karen, Jimenez, Norman, Martinez-Barrio, Julia, Galindo, María, Calvo Alén, Jaime, del Campo Pérez, Victor, Itzazelaia, Esther Uriarte, Tomero, Eva, Freire-González, Mercedes, Martínez Taboada, Víctor, Salgado, Eva, Vela, Paloma, Fernandez-Nebro, Antonio, Olivé, Alejandro, Narváez, Javier, Menor-Almagro, Raúl, and Santos Soler, Gregorio

Published
2024
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33. Integrative Clinical, Molecular, and Computational Analysis Identify Novel Biomarkers and Differential Profiles of Anti-TNF Response in Rheumatoid Arthritis

Author

Maria Luque-Tévar, Carlos Perez-Sanchez, Alejandra Mª Patiño-Trives, Nuria Barbarroja, Ivan Arias de la Rosa, Mª Carmen Abalos-Aguilera, Juan Antonio Marin-Sanz, Desiree Ruiz-Vilchez, Rafaela Ortega-Castro, Pilar Font, Clementina Lopez-Medina, Montserrat Romero-Gomez, Carlos Rodriguez-Escalera, Jose Perez-Venegas, Mª Dolores Ruiz-Montesinos, Carmen Dominguez, Carmen Romero-Barco, Antonio Fernandez-Nebro, Natalia Mena-Vazquez, Jose Luis Marenco, Julia Uceda-Montañez, Mª Dolores Toledo-Coello, M. Angeles Aguirre, Alejandro Escudero-Contreras, Eduardo Collantes-Estevez, and Chary Lopez-Pedrera

Subjects
rheumatoid arthritis, anti-TNF agents, inflammation, NEtosis, microRNAs, machine learning, Immunologic diseases. Allergy, RC581-607
Abstract

Background: This prospective multicenter study developed an integrative clinical and molecular longitudinal study in Rheumatoid Arthritis (RA) patients to explore changes in serologic parameters following anti-TNF therapy (TNF inhibitors, TNFi) and built on machine-learning algorithms aimed at the prediction of TNFi response, based on clinical and molecular profiles of RA patients.Methods: A total of 104 RA patients from two independent cohorts undergoing TNFi and 29 healthy donors (HD) were enrolled for the discovery and validation of prediction biomarkers. Serum samples were obtained at baseline and 6 months after treatment, and therapeutic efficacy was evaluated. Serum inflammatory profile, oxidative stress markers and NETosis-derived bioproducts were quantified and miRNomes were recognized by next-generation sequencing. Then, clinical and molecular changes induced by TNFi were delineated. Clinical and molecular signatures predictors of clinical response were assessed with supervised machine learning methods, using regularized logistic regressions.Results: Altered inflammatory, oxidative and NETosis-derived biomolecules were found in RA patients vs. HD, closely interconnected and associated with specific miRNA profiles. This altered molecular profile allowed the unsupervised division of three clusters of RA patients, showing distinctive clinical phenotypes, further linked to the TNFi effectiveness. Moreover, TNFi treatment reversed the molecular alterations in parallel to the clinical outcome. Machine-learning algorithms in the discovery cohort identified both, clinical and molecular signatures as potential predictors of response to TNFi treatment with high accuracy, which was further increased when both features were integrated in a mixed model (AUC: 0.91). These results were confirmed in the validation cohort.Conclusions: Our overall data suggest that: 1. RA patients undergoing anti-TNF-therapy conform distinctive clusters based on altered molecular profiles, which are directly linked to their clinical status at baseline. 2. Clinical effectiveness of anti-TNF therapy was divergent among these molecular clusters and associated with a specific modulation of the inflammatory response, the reestablishment of the altered oxidative status, the reduction of NETosis, and the reversion of related altered miRNAs. 3. The integrative analysis of the clinical and molecular profiles using machine learning allows the identification of novel signatures as potential predictors of therapeutic response to TNFi therapy.

Published
2021
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34. Déchiffrer la pneumopathie interstitielle diffuse associée à la polyarthrite rhumatoïde en utilisant une analyse en cluster hiérarchique non supervisée : résultats d’une collaboration internationale

Author

Juge, P.A., primary, Granger, B., additional, El Houari, L., additional, Mcdermott, G., additional, Doyle, T., additional, Kelly, C., additional, Gouri, K., additional, Vassallo, R., additional, Alarcon Calderon, A., additional, Kalyoncu, U., additional, Gonzales, A., additional, Mena-Vazquez, N., additional, Rojas-Gimenez, M., additional, Dos Santos-Sobrin, R., additional, Retuerto-Guerrero, M., additional, Vadillo-Font, C., additional, Vela, P., additional, Fernandez-Nebro, A., additional, Escudero-Contreras, A., additional, Pérez-Pampin, E., additional, Pablos-Alvarez, J.L., additional, Abasolo, L., additional, Hyldgaard, C., additional, Froidure, A., additional, Durez, P., additional, Rojas-Serrano, J., additional, Van Moorsel, C., additional, Grutters, J., additional, Kawano, L., additional, Lucas, C., additional, Jouneau, S., additional, Sanmartí, R., additional, Castellanos Moreira, R., additional, Antoniou, K., additional, Molina Molina, M., additional, Solomon, J., additional, Raia, S., additional, González-Gay, M.A., additional, Atienza-Mateo, B., additional, Flouda, S., additional, Effrosyni, M., additional, Boumpas, D., additional, Papiris, S., additional, Karageorgas, T., additional, Sebastiani, M., additional, Manfredi, A., additional, Duarte, A.C., additional, Crestani, B., additional, Sparks, J., additional, and Dieudé, P., additional

Published
2023
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35. Interpretable Inflammation Landscape of Circulating Immune cells

Author

Jiménez-Gracia, Laura, primary, Maspero, Davide, additional, Aguilar-Fernández, Sergio, additional, Craighero, Francesco, additional, Ruiz, Sara, additional, Marchese, Domenica, additional, Caratu, Ginevra, additional, Elosua-Bayes, Marc, additional, Abdalfatah, Mohamed, additional, Sanzo-Machuca, Angela, additional, M. Corraliza, Ana, additional, Massoni-Badosa, Ramon, additional, A. Tran, Hoang, additional, Normand, Rachelly, additional, Nestor, Jacquelyn, additional, Hong, Yourae, additional, Kole, Tessa, additional, van der Velde, Petra, additional, Alleblas, Frederique, additional, Pedretti, Flaminia, additional, Aterido, Adria, additional, Banchero, Martin, additional, Soriano, German, additional, Roman, Eva, additional, van den Berge, Maarten, additional, Salas, Azucena, additional, Carrascosa, Jose Manuel, additional, Fernandez Nebro, Antonio, additional, Domenech, Eugeni, additional, Cañete, Juan, additional, Tornero, Jesus, additional, Perez-Gisbert, Javier, additional, Choy, Ernest, additional, Girolomoni, Giampiero, additional, Siegmund, Britta, additional, Julia, Antonio, additional, Serra, Violeta, additional, Elosua, Roberto, additional, Tejpar, Sabine, additional, Vidal, Silvia, additional, Nawijn, Martijn C., additional, Marsal, Sara, additional, Vandergheynst, Pierre, additional, Villani, Alexandra-Chloe, additional, Nieto, Juan C., additional, and Heyn, Holger, additional

Published
2023
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36. Incidence, associated factors and clinical impact of severe infections in a large, multicentric cohort of patients with systemic lupus erythematosus

Author

Rúa-Figueroa, Íñigo, López-Longo, Javier, Galindo-Izquierdo, María, Calvo-Alén, Jaime, Del Campo, Víctor, Olivé-Marqués, Alejandro, Pérez-Vicente, Sabina, Fernández-Nebro, Antonio, Andrés, Mariano, Erausquin, Celia, Tomero, Eva, Horcada, Loreto, Uriarte, Esther, Freire, Mercedes, Montilla, Carlos, Sánchez-Atrio, Ana, Santos, Gregorio, Boteanu, Alina, Díez-Álvarez, Elvira, Narváez, Javier, Martínez-Taboada, Víctor, Silva-Fernández, Lucía, Ruiz-Lucea, Esther, Andreu, José Luis, Hernández-Beriain, José Ángel, Gantes, Marian, Hernández-Cruz, Blanca, Pérez-Venegas, José, Pecondón-Español, Ángela, Marras, Carlos, Ibáñez-Barceló, Mónica, Bonilla, Gema, Torrente, Vicente, Castellví, Iván, Alegre, Juan José, Calvet, Joan, Marenco, Jose Luis, Raya, Enrique, Vázquez, Tomás, Quevedo, Victor, Muñoz-Fernández, Santiago, Rodríguez-Gómez, Manuel, Ibáñez, Jesús, and Pego-Reigosa, José M.

Published
2017
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37. Ixekizumab for the treatment of patients with active psoriatic arthritis and an inadequate response to tumour necrosis factor inhibitors: results from the 24-week randomised, double-blind, placebo-controlled period of the SPIRIT-P2 phase 3 trial

Author

Ahmed, Khalid, Alper, Jeffrey, Barkham, Nichol, Bennett, Ralph E., García, Francisco Javier Blanco, Alonso, Ricardo Blanco, Blumstein, Howard B., Brooks, Michael S., Burmester, Gerd-Rüdiger, Cagnoli, Patricia, Caldron, Paul H., Cantagrel, Alain, Chen, Der-Yuan, Churchill, Melvin A., Jr, Codding, Christine E., Combe, Benard, Deane, Peter M.G., Del Giudice, Jose, Deodhar, Atul A., Dhar, Rajat K., Dokoupilova, Eva, Egan, Rita M., Everding, Andrea, Galíndez, Eva, Genovese, Mark, Goddard, David H., Gottlieb, Alice, Goupille, Philippe, Griffin, Robert M., Gupta, Ramesh C., Hall, Stephen, Hatti, Kalpita, Howell, Mary P., Huang, Yu-Huei, Jajoo, Ramina, Janssen, Namieta M., Kiltz, Uta, Kivitz, Alan J., Klein, Steven J., Korkosz, Mariusz P., Kotha, Roshan, Kremer, Joel M., Lue, Cummins, de la Fuente, José Luis Marenco, Marzo-Ortega, Helena, Masmitja, Jordi Gratacós, Mease, Philip J., Meroni, Pier Luigi, Mueller, Eric C., Nandagudi, Anupama C., Nash, Peter, Fernández-Nebro, Antonio, Neuwelt, Clark M., Orbai, Ana Maria, Oza, Meera R., Parks, Deborah L., Pattanaik, Debendra, Rell-Bakalarska, Maria E., Rosmarin, David, Roussou, Euthalia, Rychlewska-Hanczewksa, Anna I., Sikes, David H., Stack, Michael T., Sunkureddi, Prashanth, Tahir, Hasan, Thaçi, Diamant, Tsai, Tsen-Fang, Turkiewicz, Anthony M., Unger, Leonore, Cabello, Raúl Veiga, Wagner, Ulf, Wei, Cheng-Chung, Wells, Alvin F., Youssef, Peter, Zielinska, Agnieszka, Kirkham, Bruce, Okada, Masato, Rahman, Proton, Burmester, Gerd-Ruediger, Adams, David H, Kerr, Lisa, Lee, Chin, and Shuler, Catherine L

Published
2017
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40. LP-171 Fibromyalgia and glucocorticoids use drives self-perceived depression in systemic lupus erythematosus: insights from a large prospective and multicenter study using Relesserpros register’s database.

Author

Rúa-Figueroa, Iñigo, primary, Martínez-Barrio, Julia, additional, Jiménez, Norman, additional, Galindo-Izquierdo, María, additional, Uriarte-Isacelaya, Esther, additional, Fernandez-Nebro, Antonio, additional, Calvo, Jaime, additional, Manrique-Arija, Sara, additional, Rosas, Jose, additional, Caño-Alameda, Rocio, additional, Narváez, J., additional, Ros, Inmaculada, additional, Aurrecoechea, Elena, additional, Torrente-Segarra, Vicenç, additional, Sanguesa, Clara, additional, Freire-González, Mercedes, additional, Tomero-Muriel, Eva, additional, Horcada, Loreto, additional, Moriano, Clara, additional, Moreno, Mireia, additional, Laura-Iñíguez, Carlota, additional, Blanco, Ricardo, additional, Pérez-Gómez, Ana, additional, Andréu-Sánchez, José Luis, additional, Garrote-Corral, Sandra, additional, Muñoz-Fernández, Santiago, additional, Bonilla, Gema, additional, Lozano-Rivas, Nuria, additional, Montilla-Morales, Carlos A, additional, Ibarguengoitia, O, additional, Expósito, Lorena, additional, Vals-Pascual, Elia, additional, Pecondon-Español, Angela, additional, Machín, Sergio, additional, Salgado-Perez, Eva, additional, Celia-Erausquin, Maria, additional, Salman-Monte, Tarek Carlos, additional, Menor-Almagro, Raúl, additional, Muñoz-Jimenez, Alejandro, additional, Altabás-González, Irene, additional, Fragío-Gil, Jorge Juan, additional, and Pego-Reigosa, Jose María, additional

Published
2023
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41. Quality Standards for Rheumatology Outpatient Clinic. The EXTRELLA Project

Author

Nolla, Joan M., Martínez, Carmen, García-Vicuña, Rosario, Seoane-Mato, Daniel, Rosario Lozano, M. Piedad, Alonso, Alberto, Alperi, Mercedes, Barbazán, Ceferino, Calvo, Jaime, Delgado, Concepción, Fernández-Nebro, Antonio, Mateo, Lourdes, Pérez Sandoval, Trinidad, Pérez Venegas, José, Rodríguez Lozano, Carlos, and Rosas, José

Published
2016
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47. OP0229 CHANGES IN THE CAUSES AND PREDICTORS OF LUPUS MORTALITY IN SPAIN THROUGH THE LAST DECADES: DATA FROM THE RELESSER REGISTRY

Author

Moriano, C., primary, Calvo-Alén, J., additional, Rua-Figueroa, I., additional, Diez Álvarez, E., additional, Bermúdez, C., additional, Martínez-Barrio, J., additional, Galindo-Izquierdo, M., additional, Olive, A., additional, Tomero Muriel, E., additional, Fernandez-Nebro, A., additional, Freire González, M., additional, Fernandez Berrizbeitia, O. B., additional, Pérez Gómez, A., additional, Uriarte Isacelaya, E., additional, Marras Fernandez Cid, C., additional, Montilla-Morales, C. A., additional, Santos Soler, G., additional, Blanco, R., additional, Rodíguez-Gómez, M., additional, Vela Casasempere, P., additional, Boteanu, A., additional, Narváez, J., additional, Martinez Taboada, V., additional, Hernández-Cruz, B., additional, Andréu Sánchez, J. L., additional, Hernandez Beriain, J. A., additional, Expósito, L., additional, Menor-Almagro, R., additional, Ibañez Barceló, M., additional, Castellví, I., additional, Galisteo, C., additional, Raya, E., additional, Quevedo Vila, V., additional, Vazquez Rodriguez, T., additional, Ibañez, J., additional, and Pego-Reigosa, J. M., additional

Published
2023
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48. OP0023 UNBIASED HIERARCHICAL CLUSTERING OF CIRCULATING MOLECULAR PROFILES IN RHEUMATOID ARTHRITIS PATIENTS DEFINES PRECISE CV RISK. EFFECTS OF TNFI, IL6RI, AND JAKINIBS

Author

Muñoz-Barrera, L., primary, Perez-Sanchez, C., additional, Cerdó, T., additional, Ortega Castro, R., additional, Calvo Gutierrez, J., additional, Pilar, F. U., additional, Seguí Azpilcueta, P., additional, Ábalos-Aguilera, M. C., additional, Ruiz, D., additional, Remuzgo Martinez, S., additional, López-Mejías, R., additional, Pérez Venegas, J. J., additional, Ruiz Montesinos, M. D., additional, Dominguez, C., additional, Rodríguez-Escalera, C., additional, Romero-Barco, C. M., additional, Fernandez-Nebro, A., additional, Mena-Vázquez, N., additional, Uceda, J., additional, Santos, C., additional, Barbarroja Puerto, N., additional, Arias de la Rosa, I., additional, Aguirre, M. A., additional, Collantes Estevez, E., additional, Escudero Contreras, A., additional, González-Gay, M. A., additional, and Lopez-Pedrera, C., additional

Published
2023
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49. AB1677 VALIDATION ANALYSIS OF THE PHYSICIAN GLOBAL ASSESSMENT (PGA) SCALE IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS INCLUDED IN RELESSER-PROS REGISTRY

Author

Cáceres Martín, L., primary, Rua-Figueroa, I., additional, Jiménez, N., additional, Galindo-Izquierdo, M., additional, Calvo-Alen, J., additional, Menor-Almagro, R., additional, Fernandez-Nebro, A., additional, Martínez-Barrio, J., additional, Rodríguez Almaraz, E., additional, Uriarte Isacelaya, E., additional, Aurrecoechea, E., additional, Mena-Vázquez, N., additional, Senabre-Gallego, J. M., additional, Bernal, J. A., additional, Pérez Gómez, A., additional, Torrente, V., additional, Narváez, J., additional, Sanguesa, C., additional, Arévalo, M., additional, Freire González, M., additional, Moriano, C., additional, Iñíguez, C. L., additional, Tomero Muriel, E., additional, Andreu, J. L., additional, Garcia Villanueva, M. J., additional, Cobo-Ibáñez, T., additional, Bonilla, G., additional, Lozano Rivas, N., additional, Horcada, L., additional, Montilla-Morales, C. A., additional, Expósito, L., additional, Ruiz Lucea, E., additional, Eloy Oller, J., additional, Pecondon-Español, A., additional, Loricera, J., additional, Nóvoa Medina, F. J., additional, Salgado Perez, E., additional, Salman Monte, T. C., additional, Muñoz Jimenez, A., additional, Fragío Gil, J. J., additional, and Pego-Reigosa, J. M., additional

Published
2023
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50. POS1041 LIPID METABOLISM IS DEEPLY ALTERED IN ACTIVE RHEUMATOID ARTHRITIS PATIENTS AND REVERSED BY ANTI-TNF, ANTI-IL6R, AND JAK-INHIBITORS

Author

Perez-Sanchez, C., primary, Muñoz-Barrera, L., additional, Cerdó, T., additional, Ortega Castro, R., additional, Calvo, J., additional, Aguirre, M. A., additional, Seguí Azpilcueta, P., additional, Arias de la Rosa, I., additional, Ábalos-Aguilera, M. C., additional, Ruiz, D., additional, Merlo, C., additional, Ortiz Buitrago, P., additional, Pérez Venegas, J. J., additional, Ruiz-Montesinos, D., additional, Dominguez, C., additional, Rodríguez-Escalera, C., additional, Romero-Barco, C. M., additional, Fernandez-Nebro, A., additional, Mena-Vázquez, N., additional, Uceda, J., additional, Santos, C., additional, Barbarroja Puerto, N., additional, Collantes Estevez, E., additional, Escudero Contreras, A., additional, and Lopez-Pedrera, C., additional

Published
2023
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