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4. Dietary Protein Restriction Improves Metabolic Dysfunction in Patients with Metabolic Syndrome in a Randomized, Controlled Trial

Author

Ferraz-Bannitz, Rafael, primary, Beraldo, Rebeca A., additional, Peluso, A. Augusto, additional, Dall, Morten, additional, Babaei, Parizad, additional, Foglietti, Rayana Cardoso, additional, Martins, Larissa Marfori, additional, Gomes, Patricia Moreira, additional, Marchini, Julio Sergio, additional, Suen, Vivian Marques Miguel, additional, de Freitas, Luiz C. Conti, additional, Navegantes, Luiz Carlos, additional, Pretti, Marco Antônio M., additional, Boroni, Mariana, additional, Treebak, Jonas T., additional, Mori, Marcelo A., additional, Foss, Milton Cesar, additional, and Foss-Freitas, Maria Cristina, additional

Published
2022
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6. Additional file 1 of Bariatric surgery can acutely modulate ER-stress and inflammation on subcutaneous adipose tissue in non-diabetic patients with obesity

Author

Ferraz-Bannitz, Rafael, Welendorf, Caroline Rossi, Coelho, Priscila Oliveira, Salgado, Wilson, Nonino, Carla Barbosa, Beraldo, Rebeca A., and Foss-Freitas, Maria Cristina

Subjects
nutritional and metabolic diseases
Abstract

Additional file 1: Table S1. Gene Expression of adipose tissue 3 and 6 months post RYGB compared with Baseline.

Published
2021
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7. Genetically determined variations of selenoprotein P are associated with antioxidant, muscular, and lipid biomarkers in response to Brazil nut consumption by patients using statins

Author

Moriguchi Watanabe, Lígia, primary, Bueno, Ana C., additional, de Lima, Livia F., additional, Ferraz-Bannitz, Rafael, additional, Dessordi, Renata, additional, Guimarães, Mariana P., additional, Foss-Freitas, Maria C., additional, Barbosa, Fernando, additional, and Navarro, Anderson M., additional

Published
2021
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10. Association between creatine kinase activity, oxidative stress and selenoproteins mRNA expression changes after Brazil nut consumption of patients using statins

Author

Watanabe, Lígia Moriguchi, primary, Fernandes de Lima, Lívia, additional, Ferraz-Bannitz, Rafael, additional, Takaara, Daniela, additional, Coimbra Romano, Beatriz, additional, Braga Costa, Telma Maria, additional, Foss de Freitas, Maria Cristina, additional, Bueno, Ana Carolina, additional, Barbosa Júnior, Fernando, additional, and Marliere Navarro, Anderson, additional

Published
2020
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11. Genetically determined variations of selenoprotein P are associated with antioxidant, muscular, and lipid biomarkers in response to Brazil nut consumption by patients using statins.

Author

Moriguchi Watanabe, Lígia, Bueno, Ana C., de Lima, Livia F., Ferraz-Bannitz, Rafael, Dessordi, Renata, Guimarães, Mariana P., Foss-Freitas, Maria C., Barbosa Jr., Fernando, and Navarro, Anderson M.

Subjects
PROTEIN metabolism, BIOMARKERS, STATINS (Cardiovascular agents), HOMEOSTASIS, BODY composition, TRIGLYCERIDES, SKELETAL muscle, MYALGIA, ACADEMIC medical centers, CLINICAL trials, SINGLE nucleotide polymorphisms, HYPERCHOLESTEREMIA, ANTIOXIDANTS, LOW density lipoproteins, CREATINE kinase, DIETARY supplements, MUSCLE weakness, GENE expression, MESSENGER RNA, DESCRIPTIVE statistics, HIGH density lipoproteins, ERYTHROCYTES, NUTS, LIPIDS, SELENIUM, PAIN management, GLUTATHIONE peroxidase, CHOLESTEROL
Abstract

Several single nucleotide polymorphisms (SNPs) could indirectly, as well directly, influence metabolic parameters related to health effects in response to selenium (Se) supplementation. This study aimed to investigate whether the selenoprotein SNPs were associated with the response of Se status biomarkers to the Brazil nut consumption in patients using statins and if the variation in Se homoeostasis could affect antioxidant protection, lipid profile, muscle homoeostasis and selenoproteins mRNA. The study was performed in the Ribeirão Preto Medical School University Hospital. Thirty-two patients using statins received one unit of Brazil nut daily for 3 months. Body composition, blood Se concentrations, erythrocyte glutathione peroxidase (GPX) activity, total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL), triacylglycerol (TAG), creatine kinase (CK) activity and gene expression of GPX1 and selenoprotein P (SELENOP) were evaluated before and after Brazil nut consumption. The volunteers were genotyped for SNP in GPX1 (rs1050450) and SELENOP (rs3877899 and rs7579). SNPs in selenoproteins were not associated with plasma and erythrocyte Se, but SNPs in SELENOP influenced the response of erythrocyte GPX activity and CK activity, TAG and LDL after Brazil nut consumption. Also, Brazil nut consumption increased GPX1 mRNA expression only in subjects with rs1050450 CC genotype. SELENOP mRNA expression was significantly lower in subjects with rs7579 GG genotype before and after the intervention. Thus, SNP in SELENOP could be associated with interindividual differences in Se homeostasis after Brazil nut consumption, emphasising the involvement of genetic variability in response to Se consumption towards health maintenance and disease prevention. [ABSTRACT FROM AUTHOR]

Published
2022
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14. Dietary Protein Restriction Reverses Metabolic Dysfunction in Patients with the Metabolic Syndrome, Randomised Controlled Trial

Author

Ferraz-Bannitz, Rafael, primary, Beraldo, Rebeca A., additional, Marfori Sampaio Martins, Larissa, additional, Moreira Gomes, Patricia, additional, Cardoso Foglietti, Rayana Eduarda, additional, Sergio Marchini, Julio, additional, Marques Miguel Suen, Vivian, additional, Carlos de Freitas, Luiz, additional, Carlos Navegantes, Luiz, additional, Mori, Marcelo A., additional, Foss, Milton Cesar, additional, and Cristina Foss-Freitas, Maria, additional

Published
2020
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