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2. Stress beliefs moderate the impact of COVID‐19 related work stress on depressive, anxiety and distress symptoms in health care workers.

Author

Laferton, Johannes A. C., Schiller, Saskia, Conrad, Daniela, Fischer, Dorothea, and Zimmermann‐Viehoff, Frank

Subjects
PSYCHOLOGY of physicians, CROSS-sectional method, SELF-evaluation, HEALTH attitudes, MENTAL health, ANXIETY, DESCRIPTIVE statistics, JOB stress, PSYCHOLOGICAL stress, COVID-19 pandemic, MENTAL depression
Abstract

Health care workers are at increased risk for mental health issues due to high psychological and physical job demands. According to a recent study, stress beliefs (i.e., believing stress to be detrimental to one's health) might influence physicians' mental health in response to a naturalistic stressor (COVID‐19 hospital working conditions). Due to a small sample size and high alpha error inflation, the suggested association needs to be interpreted with caution. The current study aims to replicate those findings in a larger sample. A cross‐sectional survey among N = 418 (64.1% female; Median age = 30–39 years) physicians and nurses of a large German medical centre was conducted during the COVID‐19 pandemic (May/June 2021). Perception of pandemic related increase of work stress was assessed via self‐report. Stress beliefs were assessed with the Beliefs About Stress Scale, and mental health symptoms were assessed with the 21‐item Depression Anxiety Stress Scale. Stress beliefs moderated the association between increased work stress and mental health symptoms. Increased work stress was associated with increased depressive, anxiety and distress symptoms only in health care workers with medium (simple slope = 2.22, p <.001; simple slope = 1.27, p <.001; simple slope = 3.19, p <.001) and high (simple slope = 3.13; p <.001; simple slope = 1.66, p <.05; simple slope = 4.33, p <.001) negative stress beliefs. Among health care workers with low negative stress beliefs increased work stress was not associated with increased depressive, anxiety and distress symptoms. This confirms negative stress beliefs as variable of interest in research on the impact of stress on mental health in health care workers. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Incidence and Resolution of Eribulin-Induced Peripheral Neuropathy (IRENE) in Locally Advanced or Metastatic Breast Cancer: Prospective Cohort Study

Author

Lück, Hans-Joachim, primary, Schmidt, Marcus, additional, Hesse, Tobias, additional, Hoffmann, Oliver, additional, Heinrich, Bernhard J, additional, Park-Simon, Tjoung-Won, additional, Grischke, Eva-Maria, additional, Weide, Rudolf, additional, Müller-Huesmann, Harald, additional, Lüdtke-Heckenkamp, Kerstin, additional, Fischer, Dorothea, additional, Zemlin, Cosima, additional, Kögel, Matthias, additional, Wu, Jane, additional, Schmitz, Helga, additional, Engelbrecht, Christian, additional, and Jackisch, Christian, additional

Published
2023
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6. Immune response of heterologous versus homologous prime-boost regimens with adenoviral vectored and mRNA COVID-19 vaccines in immunocompromised patients

Author

Chu, Chang, primary, Schönbrunn, Anne, additional, Fischer, Dorothea, additional, Liu, Yvonne, additional, Hocher, Johann-Georg, additional, Weinerth, Jutta, additional, Klemm, Kristin, additional, von Baehr, Volker, additional, Krämer, Bernhard K., additional, Elitok, Saban, additional, and Hocher, Berthold, additional

Published
2023
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9. Abstract OT2-01-09: ABEMACARE: Abemaciclib in Combination with Endocrine Therapy as First Line Therapy in Metastatic Breast Cancer Patients with Symptomatic Visceral Metastases or High Tumor Burden – A prospective multicenter observational study

Author

Ettl, Johannes, primary, Sophia, Ramsperger, additional, Kotzur, Franziska, additional, Müller, Lothar, additional, Seitz, Stephan, additional, Fasching, Peter A., additional, Jilg, Stefanie, additional, Fischer, Dorothea, additional, Egert-Schwender, Silvia, additional, Victora, Kehl, additional, Reuning, Ute, additional, Rösch, Romina, additional, Rief, Lukas, additional, Bronger, Holger, additional, Winter, Christof, additional, and Kiechle, Marion, additional

Published
2023
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10. 2022-RA-576-ESGO Expression VIII – first study of individual perception and level of information of patients with low grade ovarian cancer and borderline tumor of the ovary in 321 patients

Author

Beckmann, Laura Naomi, primary, Alavi, Sara, additional, Keller, Maren, additional, Liebrich, Clemens, additional, Kubiak, Karol, additional, Wimberger, Pauline, additional, Czolk, Vera, additional, Ligl-Löhner, Anette, additional, Enzinger, Hans-Martin, additional, Burdack, Aline, additional, Fischer, Dorothea, additional, Terhaag, Jürgen, additional, Müller, Cornelia, additional, Hanf, Volker, additional, Condic, Mateja, additional, Kunz, Georg, additional, Lantzsch, Tilmann, additional, Schilling, Ute, additional, Oskay-Özcelik, Gülten, additional, and Sehouli, Jalid, additional

Published
2022
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11. 2022-RA-837-ESGO Characterization of long-term survivor and maintenance therapy in relapsed ovarian cancer (CAROLIN)- Intergroup study NOGGO/A-AGO

Author

Grabowski, Jacek, primary, Braicu, Ioana Elena, additional, Petru, Edgar, additional, Woopen, Hannah, additional, Müller, Andreas, additional, Virk, Yasemin, additional, Bogner, Gerhard, additional, Hensel, Manfred, additional, Zocholl, Dario, additional, Eggemann, Holm, additional, Marth, Christian, additional, Condic, Mateja, additional, Dannecker, Christian, additional, Fischer, Dorothea, additional, and Sehouli, Jalid, additional

Published
2022
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12. Gynecologic oncologists’ attitudes and practices relating to integrative medicine: results of a nationwide AGO survey

Author

Klein, Evelyn, Beckmann, Matthias W., Bader, Werner, Brucker, Cosima, Dobos, Gustav, Fischer, Dorothea, Hanf, Volker, Hasenburg, Annette, Jud, Sebastian M., Kalder, Matthias, Kiechle, Marion, Kümmel, Sherko, Müller, Andreas, Müller, Myrjam-Alice T., Paepke, Daniela, Rotmann, Andre-Robert, Schütz, Florian, Scharl, Anton, Voiss, Petra, Wallwiener, Markus, Witt, Claudia, and Hack, Carolin C.

Published
2017
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15. Immune response of heterologous versus homologous prime-boost regimens with adenoviral vectored and mRNA COVID-19 vaccines in immunocompromised patients.

Author

Chang Chu, Schönbrunn, Anne, Fischer, Dorothea, Liu, Yvonne, Hocher, Johann-Georg, Weinerth, Jutta, Klemm, Kristin, von Baehr, Volker, Krämer, Bernhard K., Elitok, Saban, and Hocher, Berthold

Subjects
IMMUNOCOMPROMISED patients, COVID-19 vaccines, IMMUNE response, CHRONIC kidney failure, HEMODIALYSIS patients, ADENOVIRUS diseases, AGAMMAGLOBULINEMIA
Abstract

Due to rare but major adverse reactions to the AstraZeneca adenoviral ChAdOx1-S-nCoV-19 vaccine (ChAd), German health authorities recommended adults under 60 who received one dose of ChAd, to receive a second dose of the BioNTech mRNA BNT162b2 vaccine (BNT) as a booster. Studies in the general population suggest an enhanced efficacy of the heterologous (ChAd-BNT) compared to the homologous (BNT-BNT) vaccination regimen. However, an analysis of the efficacy in patient populations with a high risk of severe COVID-19 due to acquired immunodeficiency is still missing. We therefore compared both vaccination regimens in healthy controls, patients with gynecological tumors after chemotherapy, patients on dialysis and patients with rheumatic diseases concerning the humoral and cellular immune response. The humoral and cellular immune response differed substantially in healthy controls compared to patients with acquired immunodeficiency. Overall, the most significant differences between the two immunization regimens were found in neutralizing antibodies. These were always higher after a heterologous immunization. Healthy controls responded well to both vaccination regimens. However, the formation of neutralizing antibodies was more pronounced after a heterologous immunization. Dialysis patients, on the other hand, only developed an adequate humoral and particularly cellular immune response after a heterologous immunization. Tumor and rheumatic patients also - to a weaker extent compared to dialysis patients - benefited from a heterologous immunization. In conclusion, the heterologous COVID-19 vaccination regimens (ChAd-BNT) seem to have an advantage over the homologous vaccination regimens, especially in immunocompromised patients such as patients with end-stage kidney disease treated with hemodialysis. [ABSTRACT FROM AUTHOR]

Published
2023
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16. Novel approach of desensitization in allergic reaction to Olaparib.

Author

Beurer, Björn M, Sprenger, Luise M, Graneß, Kristina, Feldmann, Freia, Warnke, Ulrich, Biersack, Maria G, and Fischer, Dorothea

Subjects
ALLERGY desensitization, OVARIAN tumors, PROTEIN kinase inhibitors, ORAL drug administration, ANTINEOPLASTIC agents, CUTANEOUS manifestations of general diseases, DRUG allergy, ENZYME inhibitors, PATIENT safety, PHARMACODYNAMICS
Abstract

Introduction: PARP (Poly ADP Ribose Polymerase) inhibitors are an effective maintenance therapy for various entities, such as BRCA (breast cancer gene) mutated or HRD (homologous recombination deficiency) positive primary platin-sensitive advanced ovarian cancer after platin induction therapy and in relapse after responding to carboplatin reinduction. Other entities are metastatic BRCA mutated pancreas, prostate and Her2-negative breast cancer. Therefore, patients with allergic reactions to PARP inhibitors should undergo a desensitization procedure to be able to receive this efficient therapy. Case report: We conducted a two-day desensitization on a 45-year-s old patient with advanced ovarian cancer who displayed symptoms of an allergic reaction to Olaparib. Management and outcome: Using an Olaparib tablet suspension, we orally administered increasing Olaparib doses, starting with 12.5 mg and reaching a cumulative dose of 387.5 mg on the first day and starting with 100 mg and reaching a cumulative dose of 600 mg on the second day, without concomitant antiallergic medication. Except for mild erythema on day one receding within the hour, no further allergic reactions appeared during desensitization. The patient has since received 300 mg of Olaparib twice a day without further complications or interruptions. Conclusion: Desensitization in a two-day suspension protocol is a safe method that ensures effective maintenance therapy for patients with allergic reactions to PARP inhibitors. [ABSTRACT FROM AUTHOR]

Published
2023
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27. Abstract OT-26-01: ABEMACARE: Abemaciclib in combination with endocrine therapy as first line therapy in metastatic breast cancer patients with symptomatic visceral metastases or high tumor burden

Author

Kotzur, Franziska, primary, Bidner, Helen, additional, Bronger, Holger, additional, Egert, Silvia, additional, Fasching, Peter A, additional, Fischer, Dorothea, additional, Kehl, Victoria, additional, Lück, Hans-Joachim, additional, Müller, Lothar, additional, Reuning, Ute, additional, Rief, Lukas, additional, Rösch, Romina, additional, Seitz, Stephan, additional, Winter, Christof, additional, Kiechle, Marion, additional, and Ettl, Johannes, additional

Published
2021
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28. Maintaining an Adult Hematology/Oncology Service at a Tertiary Care Center during the SARS-CoV-2 Pandemic: An Eight-Week-Experience with a Newly Implemented Procedural Plan

Author

Hemmati, Philipp G., primary, Fischer, Dorothea, additional, Breywisch, Frank, additional, Wohlfarth, Sabine, additional, Kramer, Matthias, additional, Paland, Matthias, additional, Tometten, Lukas, additional, Badakhshi, Harun, additional, Ripberger, Gerald, additional, and Maschmeyer, Georg, additional

Published
2021
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30. NOGGO Ov-42/MAMOC: Rucaparib maintenance after bevacizumab maintenance following carboplatin-based first line-chemotherapy in ovarian cancer patients.

Author

Braicu, Elena Ioana, primary, Wimberger, Pauline, additional, Richter, Rolf, additional, Keller, Maren, additional, Krabisch, Petra, additional, Deryal, Mustafa, additional, Runnebaum, Ingo B., additional, Witteler, Ralf, additional, Bangemann, Nikola, additional, Marmé, Frederik, additional, Eichbaum, Michael, additional, Heitz, Florian, additional, Schmalfeldt, Barbara, additional, Egger, Eva, additional, Fischer, Dorothea, additional, Chekerov, Radoslav, additional, Grabowski, Jacek P., additional, and Sehouli, Jalid, additional

Published
2020
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33. Multiple sclerosis and pregnancy: what does the patient think? a questionnaire study

Author

Moser Andreas, Fischer Dorothea, and Albrecht Peter

Subjects
Medicine, Biology (General), QH301-705.5, Science (General), Q1-390
Abstract

Abstract Background Multiple Sclerosis (MS) is primarily a disease of women in their childbearing years. Pregnancy and puerperium have opposite effects on the course of the disease. Nevertheless, no studies have been carried out yet on the level of information among female MS-patients regarding the interaction between MS and pregnancy. Findings Demographic data, clinical features of MS, course of MS during pregnancy and puerperium as well as knowledge concerning MS and pregnancy were evaluated by means of a questionnaire in 154 female MS-patients. The level of information was significantly higher (p < 0.001) in women who had been pregnant in the past with the diagnosis MS known at this point of time. Furthermore patients reported about a lower frequency of relapses during pregnancy and a higher frequency of relapses in the first six months after giving birth. Conclusions The findings illustrate a lack of knowledge in female MS-patients concerning the interactions of MS and pregnancy. In order to make their own independent decision based on scientific facts known to date, female MS-patients need to be better informed on issues regarding MS and pregnancy.

Published
2010
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34. Psychosocial and family‐centered support among breast cancer patients with dependent children.

Author

Hammersen, Friederike, Pursche, Telja, Fischer, Dorothea, Katalinic, Alexander, and Waldmann, Annika

Subjects
SOCIAL support, CHILD patients, BREAST cancer, STATISTICAL hypothesis testing, CANCER patients, QUALITY of life
Abstract

Objective: To evaluate the psychosocial situation of breast cancer (BC) patients with dependent children, with regard to who used family‐centered psychosocial support (PS) services, reasons against using it, as well as existing, unmet needs, and current PS need. Methods: Data were collected via survey and patient files during an inpatient rehabilitation program for mothers with BC, who were accompanied by a child <12 years. Descriptive statistics and tests for statistical significance were used. Results: Out of the total of 561 patients, 23.0% had used family‐centered PS services before. Common reasons against it were enough support, no anticipated need and organizational issues. Patients stated a high number of unmet needs. The most urgent ones related to their children. About 59.3% of mothers stated a current PS need (PSN) and 33.3% a need for their children. Little social support and a worse maternal HRQOL, but not time since diagnosis, were related to a higher PSN in mothers and children (bivariate association). Conclusion: Among BC patients with dependent children, clinicians need to take the whole family and their support needs into account. They should know about the existing organizational barriers, which need to be overcome with the help of tailored offers. Patients with low HRQOL, little social support and single‐mothers (with regard to children's PSN) need special attention as these can be indicators of high PSN. [ABSTRACT FROM AUTHOR]

Published
2021
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35. Conditional Disease-Free and Overall Survival of 1,858 Young Women with Non-Metastatic Breast Cancer and with Participation in a Post-Therapeutic Rehab Programme according to Clinical Subtypes.

Author

Pruessmann, Jonathan, Pursche, Telja, Hammersen, Friederike, Katalinic, Alexander, Fischer, Dorothea, and Waldmann, Annika

Subjects
SOCIAL participation, METASTASIS, CANCER patients, SURVIVAL analysis (Biometry), DESCRIPTIVE statistics, WOMEN'S health, BREAST tumors, PROPORTIONAL hazards models
Abstract

Background: Breast cancer in young women is associated with unfavourable tumour biology and is the main cause of death in this group. Conditional survival analysis estimates survival rates under the pre-condition of already having survived a certain time. Objectives: To describe conditional disease-free and overall survival of female breast cancer patients according to clinical subtypes and age. Methods: This study analyses information from 1,858 breast cancer patients aged between 21 and 54 years, who were taking part in a post-therapeutic rehab programme (time between diagnosis and rehab start: maximum 24, median 11 months). Mean follow-up time was 3.6 years. We describe biological, clinical and pathological features in regard to different age groups (<40 and ≥40 years) and report conditional 5-year survival rates for overall and disease-free survival, and Cox proportional hazard models. Results: Very young and young patients differed in regard to hormone receptor negativity, tumour grade, lymphovascular invasion, and molecular subtypes. Young women bore triple-negative and HER2-like disease more frequently. Conditional 5-year overall survival did not differ substantially between women <40 and 40–54 years of age (95 vs. 96%). It was highest for women with cancer of the luminal A subtype (98%) and lowest for the triple-negative subtype (91%). Lymphangiosis was a significant predictor of death. Results for disease-free survival were comparable. Conclusions: Conditional 5-year overall survival after non-metastatic breast cancer was as high as 95.5%, and disease-free survival was 85.2%. When controlling for time between diagnosis and rehab start, molecular subtypes influenced overall and disease-free survival prospects. When additionally controlling for clinical characteristics, this effect only remained stable for disease-free survival. [ABSTRACT FROM AUTHOR]

Published
2021
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36. Deutsch in den Genfer Primarschulen: Eine qualitative Analyse von sechs Expertinneninterviews

Author

Fischer, Dorothea and Elmiger, Daniel

Subjects
Enseignement de l'allemand, Genève, ddc:430/830, Analyse discursive, Représentations, Enseignement/apprentissage, Allemand, Langue étrangère, Suisse
Abstract

Ce travail s'intéresse à l'enseignement de l'allemand à l'école primaire à Genève. Ce sujet, et en général l'enseignement des langues étrangères en Suisse, est fréquemment débattu dans les médias et a fait l'objet de réformes concernant aussi bien la coordination au niveau national que le plan d'étude romand et les manuels scolaires. Il fait une analyse qualitative sur la base d'entretiens semi-directifs afin de considérer la situation complexe de l'enseignement de l'allemand à travers la perspective de six enseignantes non germanophones.

Published
2017

37. Use of Complementary and Alternative Medicine among Young Patients with Breast Cancer.

Author

Hammersen, Friederike, Pursche, Telja, Fischer, Dorothea, Katalinic, Alexander, and Waldmann, Annika

Subjects
BREAST tumor treatment, ALTERNATIVE medicine, BREAST tumors, CANCER patients, DIETARY supplements, EMPLOYMENT, IMMUNITY, HEALTH insurance, MOTHERS, QUESTIONNAIRES, EDUCATIONAL attainment, PATIENTS' attitudes, DESCRIPTIVE statistics, PATIENT decision making, ADULTS
Abstract

Background: Complementary and alternative medicine (CAM) has received increasing attention in Western countries and is especially common among breast cancer (BC) patients. So far, its effectiveness has not been well studied, which is in part due to the contextuality of CAM along with a lack of information of why patients use it. Objectives: Young BC patients constitute a special patient group regarding clinical characteristics, QOL, and their role in society. Since little is known about their CAM use, this study aimed at exploring it as well as their reasons for CAM use. Methods: Data on CAM and sociodemographics were collected via questionnaire in the context of a rehabilitation program for young mothers with BC. Initial BC diagnoses were between 2009 and 2014 (recruitment period 2012–2015). Clinical characteristics were derived from the patient files. Descriptive statistics were used to describe frequencies and statistically significant differences were tested. Results: Among the 827 patients, with an average age of 39.6 years, 62.5% had used CAM with regard to their cancer. CAM use was significantly higher in women with higher educational level, higher employment status, and statutory health insurance, respectively. The average monthly expenses on CAM were EUR 50. Every 5th woman used CAM without her physician's knowledge. The types most often used were dietary supplements with vitamins or minerals. The most frequent reasons for CAM use were to strengthen the immune system, support conventional medicine, and combat side effects. Conclusions: CAM plays an important role for young BC patients with regard to prevalence and monthly expenses, and was used for a wide range of reasons. Certain subgroups with more frequent CAM use could be identified. Physicians should therefore proactively talk about CAM with their young BC patients, so that patients do not need to rely on information sources on CAM outside the medical system. [ABSTRACT FROM AUTHOR]

Published
2020
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39. Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial

Author

Martin, Miguel, primary, Holmes, Frankie A, additional, Ejlertsen, Bent, additional, Delaloge, Suzette, additional, Moy, Beverly, additional, Iwata, Hiroji, additional, von Minckwitz, Gunter, additional, Chia, Stephen K L, additional, Mansi, Janine, additional, Barrios, Carlos H, additional, Gnant, Michael, additional, Tomašević, Zorica, additional, Denduluri, Neelima, additional, Šeparović, Robert, additional, Gokmen, Erhan, additional, Bashford, Anna, additional, Ruiz Borrego, Manuel, additional, Kim, Sung-Bae, additional, Jakobsen, Erik Hugger, additional, Ciceniene, Audrone, additional, Inoue, Kenichi, additional, Overkamp, Friedrich, additional, Heijns, Joan B, additional, Armstrong, Anne C, additional, Link, John S, additional, Joy, Anil Abraham, additional, Bryce, Richard, additional, Wong, Alvin, additional, Moran, Susan, additional, Yao, Bin, additional, Xu, Feng, additional, Auerbach, Alan, additional, Buyse, Marc, additional, Chan, Arlene, additional, Harvey, Vernon, additional, Tomek, Rudolf, additional, Robert, Nicholas J., additional, Gore, Ira, additional, Smith, John W., additional, Masuda, Norikazu, additional, Di Sean Kendall, S., additional, Harker, William Graydon, additional, Petrakova, Katarina, additional, Guerrero Zotano, Angel, additional, Simon, Amparo Ruiz, additional, Konstantinovic, Zora Neskovic, additional, Iannotti, Nicholas O., additional, Tassone, Pierfrancesco, additional, Rodriguez, Gladys I., additional, Jáñez Martinez, Noelia, additional, Crespo Massieu, Carmen, additional, Smickoska, Snezana, additional, Somali, Isil, additional, Yilmaz, Ugur, additional, Alonso, Mirta Garcia, additional, Rosales, Adolfo Murias, additional, Cold, Soeren, additional, Knoop, Ann Soegaard, additional, Patt, Debra, additional, Hellerstedt, Beth A., additional, Morales Murillo, Serafin, additional, Mayer, Ingrid A., additional, Means-Powell, Julie Ann, additional, Hui, Rina, additional, Senecal, Francis M., additional, De Boer, Richard Hendry, additional, Shen, Zhenzhou, additional, Luczak, Adam Andrzej, additional, Chui, Joanna W.Y., additional, Tsang, Janice Wing-hang, additional, Lang, Istvan, additional, Rai, Yoshiaki, additional, Hozumi, Yasuo, additional, Ten Tije, Albert J., additional, Bhandari, Manish, additional, Osborne, Cynthia R.C., additional, Ohtani, Shoichiro, additional, Higaki, Kenji, additional, Watanabe, Kenichi, additional, Taguchi, Kazunori, additional, Takahashi, Masato, additional, Filipovic, Sladjana, additional, Hansen, Vincent L., additional, Rao, Vijayarama Phooshkooru, additional, Gupta, Manish, additional, Petrov, Petar, additional, Coudert, Bruno, additional, Vojnovic, Zeljko, additional, Polya, Zsofia, additional, Miyaki, Toshiko, additional, Yamamoto, Naohito, additional, Brincat, Stephen, additional, Lesniewski-Kmak, Krzysztof, additional, Chmielowska, Ewa, additional, Birhiray, Ruemu E., additional, Citron, Marc L., additional, Papish, Steven William, additional, Berry, William R., additional, Langkjer, Sven Tyge, additional, Garcia Sáenz, José Angel, additional, Arance, Ana Maria, additional, Efrat, Noa, additional, Sarosiek, Tomasz, additional, Grzeda, Lukasz, additional, Manalo, Yvonne, additional, Smith, Julie C., additional, Vaziri, Irfan, additional, Healey, Tabitha, additional, Rahim, Yasmin, additional, Luk, Cynthia, additional, Dingle, Brian, additional, Franco, Sandra, additional, Sorensen, Peter Grundtvig, additional, Anand, Anjana, additional, Khan, Sarah, additional, Fountzilas, George, additional, Aogi, Kenjiro, additional, Shimizu, Satoru, additional, Mikulova, Milada, additional, Spanik, Stanislav, additional, Somer, Robert A., additional, Flynn, Patrick J., additional, Coward, Jermaine, additional, Mainwaring, Paul, additional, Jerusalem, Guy, additional, Segura-Ojezzar, Carine, additional, Levy, Christelle, additional, Delozier, Thierry, additional, Khayat, David, additional, Coleman, Robert E., additional, Rolles, Martin J., additional, Maisano, Robert, additional, Nardi, Mario, additional, Ito, Yoshinori, additional, Yumuk, Perran Fulden, additional, Basaran, Gul, additional, Serdar Turhal, Nazim, additional, Wilkinson, Mary J., additional, Green, Nathan B., additional, Sidrys, Algis P., additional, Hallmeyer, Sigrun, additional, Testori, Douglas J., additional, Sridhar, Srikala, additional, Chang, Jose, additional, Sun, Qiang, additional, Jara-Sanchez, Carlos, additional, Rubio, Xabier, additional, Garrido, Maria Lomas, additional, De La Haba Rodriguez, Juan Rafael, additional, Perello Martorell, Antonia, additional, Avelia Mestre, Antoni, additional, Rifa Ferrer, Julio, additional, del Barco Berron, Sonia, additional, Nagy, Zsuzsanna, additional, Tanaka, Maki, additional, Im, Young-Hyuck, additional, Carroll, Robert R., additional, Dickerson, Laura C., additional, Mace, Joseph R., additional, Rivera, Ragene, additional, Klein, Leonard M., additional, Ruxer, Robert, additional, Wilks, Sharon T., additional, Kotasek, Dusan, additional, Popov, Vasil, additional, Taskova, Violina, additional, Marinova-Venkova, Violetka, additional, Timcheva, Constanta, additional, Desbiens, Christine, additional, Ayoub, Jean-Pierre, additional, Grenier, Debjani, additional, Marschner, Norbert, additional, Tesch, Hans, additional, Lueck, Hans-Joachim, additional, Janssen, Jan, additional, Schwaner, Ingo, additional, Wahlstrom, Stine, additional, Brix, Eva Harder, additional, Vallentin, Susanne, additional, Kristensen, Dan, additional, Andreeva, Anna, additional, Glavicic, Vesna, additional, Calvo Plaza, Isabel, additional, Anton Torres, Antonio, additional, Veyret, Corinne, additional, Bergerat, Jean-Pierre, additional, Bourbouloux, Emmanuelle, additional, Ella, Wendy Ann, additional, Algurafi, Hafiz, additional, Robinson, Anne, additional, Kim, Seung Jin, additional, Taguchi, Tetsuya, additional, Juozaityte, Elona, additional, Madretsma, Stanley, additional, Radema, Sandra, additional, Czerniawska-Meier, Malgorzata, additional, Rogowski, Wojciech, additional, Wagnerova, Maria, additional, Richards, Donald A., additional, Tan-Chiu, Elizabeth, additional, Vasileios, Asskikis, additional, Henderson, Charles Arthur, additional, Holden, Viran Roger, additional, Wang, Xiaojia, additional, Tong, Zhongsheng, additional, Yang, Junlan, additional, Gonzalez, Manuel Enrique, additional, Rezai, Mahdi, additional, Hackmann, John, additional, de Dueñas, Eduardo Martinez, additional, de las Heras, Begoña Bermejo, additional, Dourthe, Louis Marie, additional, Chocteau-Bouju, Dorothee, additional, Bougnoux, Philippe, additional, Kakolyris, Stylianos, additional, Kalofonos, Haralabos, additional, Pectasidis, Dimitrios, additional, Ng, Ting Ying, additional, Pajkos, Gabor, additional, Somogyine, Eva Ezer, additional, Tonini, Giuseppe, additional, Giuffrida, Dario, additional, Takao, Shintaro, additional, Ishitobi, Makoto, additional, Inaji, Hideo, additional, Tokuda, Yutaka, additional, Wozniak, Katarzyna, additional, Lungulescu, Dan, additional, Lu, Yen-Shen, additional, Chang, King-Jen, additional, Hill, Julian, additional, Croot, Christopher Charles, additional, Dekker, Albert, additional, Belman, Neil D., additional, Conde, Miguel, additional, Michaelson, Richard A., additional, Kemmer, Kathleen, additional, Chui, Stephen, additional, Luoh, Shiuh-Wen, additional, Nahum, Kenneth, additional, Greenspan, Andrew R., additional, Nichols, Joni C., additional, Encarnacion, Carlos A., additional, Niederman, Thomas M.J., additional, Lee, Theresa, additional, Alexander, Roland, additional, Gordon, Robert, additional, Tomova, Antoanet, additional, Rauch, Daniel, additional, Popescu, Razvan Andrei, additional, Rojas, Gustavo Adolfo, additional, Vanasek, Jaroslav, additional, Neunhoeffer, Tanja, additional, Barinoff, Jana, additional, Graffunder, Gerd, additional, Wolfgang, Abenhardt, additional, Bojko, Peter, additional, Heinrich, Bernhard, additional, von der Assen, Albert, additional, Antonovic, Bogovic Jurij, additional, Adrian, Lene, additional, Ramos Vazquez, Manuel, additional, Gonzalez Santiago, Santiago, additional, Dieras, Veronique, additional, Bishop, Jill Mercia, additional, Perren, Timothy John, additional, Varthalitis, Ioannis, additional, Mavroudis, Dimitris, additional, Georgoulias, Vassilis, additional, Chow, Louis W.C., additional, Yau, Chung Cheung Thomas, additional, Liang, Raymond Hin-Suen, additional, Pikó, Béla, additional, Wéber, Agnes, additional, Kaufman, Bella, additional, Drumea, Karen, additional, Nuzzo, Francesco, additional, De Matteis, Andrea, additional, Carteni, Giacomo, additional, Tokunaga, Eriko, additional, Ishida, Mayumi, additional, Ohno, Shinji, additional, Sato, Nobuaki, additional, Kuroi, Katsumasa, additional, Nishimura, Reiki, additional, Watanabe, Junichiro, additional, Choi, Yoon Ji, additional, Park, Kyong Hwa, additional, Wojtukiewicz, Marek, additional, Jassem, Jacek, additional, Loman, Niklas, additional, Askoy, Sercan, additional, Altundag, Mustafa Kadri, additional, Saip, Pinar, additional, Ali, Muhammad Amjad, additional, Wade, James Lloyd, additional, Chien, Amy Jo, additional, Brandt, Debra, additional, Novik, Yelena, additional, Jani, Chirag, additional, Rice, Robert L., additional, Gaffar, Yousuf A. R, additional, Keaton, Mark R., additional, Bajaj, Rajesh, additional, Kimmick, Gretchen, additional, Campbell, David, additional, Turnquest, Theodore, additional, Lucas, Sideras, additional, Dube, Pierre, additional, Xu, Binghe, additional, Schilling, Joerg, additional, Apel, Klaus, additional, Vestlev, Peter Michael, additional, Jensen, Brita Bjerregaard, additional, Haahr, Vera, additional, Lescure, Alvaro Rodriguez, additional, Grana Suarez, Begona, additional, Saura Manich, Cristina, additional, Jacquin, Jean-Philippe, additional, Samreen, Ahmed, additional, Boiangiu, Ion, additional, Dank, Magdolna, additional, Falci, Cristina, additional, Jirillo, Antonio, additional, Cinieri, Saverio, additional, Ueno, Takayuki, additional, Sato, Fumiaki, additional, Yamashiro, Hiroyasu, additional, Sugie, Tomoharu, additional, Lee, Keun Seok, additional, Ro, Jung Sil, additional, Park, In Hae, additional, Bustam, Anita Zarina, additional, Suszko-Kazarnowicz, Malgorzata, additional, Piktel, Artur, additional, Krzemieniecki, Krzysztof, additional, Iorga, Polizenia Georgeta, additional, Yap, Yoon Sim, additional, Kakalejcik, Marian, additional, Sevinc, Alper, additional, Ozguroglu, Mustafa, additional, Chen, Shin-Cheh, additional, Greenberg, Richard H., additional, Eisemann, Allan Daniel, additional, Droder, Robert, additional, Abbasi, M. Rashid, additional, Vaysburd, Marina, additional, Caldera, Humberto Jose, additional, Haley, Barbara Bacsik, additional, Robin, Erwin, additional, Inhorn, Roger C., additional, Hufnagel, David, additional, Kenyon, Peter D., additional, Spremulli, Ellen, additional, Silverman, Paula, additional, Jain, Sharad, additional, Weigand, Robert, additional, Mebis, Jeroen, additional, Koynova, Tatyana, additional, Lesperance, Bernard, additional, Prausova, Jana, additional, Kohne, Claus-Henning, additional, Schneeweiss, Andreas, additional, Jackisch, Christian, additional, Fuxius, Stefan, additional, Cubedo Cervera, Ricardo, additional, Urruticoechea Ribate, Ander, additional, Pernas Simon, Sonia, additional, Valero Gallego, Jose, additional, Arcusa Lanza, Angels, additional, del Pilar Alvarez, Maria, additional, Florian Gerico, Jesus, additional, Cany, Laurent, additional, Stebbing, Justin, additional, Labudovic, Dejan, additional, Gugic, Damir, additional, Vrbanec, Damir, additional, Roila, Fausto, additional, Barni, Sandro, additional, Bidoli, Paolo, additional, Mukai, Hirofumi, additional, Bermudez, Vanessa, additional, Eniu, Alexandru, additional, Mirtsching, Barry C., additional, Ibrahim, Emad, additional, Trey, Joan, additional, Hergenroeder, Paul Francis, additional, Mahmood, Aftab, additional, Gonzalez, Anneliese, additional, Kaplan, Edward H., additional, Ban, Stacy, additional, Patel, Dhimant, additional, Clowney, Billy, additional, Hoelzer, Karen, additional, Schwartz, Garry H., additional, Salkeni, Mohamed, additional, Abraham, Jame, additional, Narula, Sunil, additional, Jabboury, Khaled, additional, Mocharnuk, Robert Scott, additional, McDonough, Richard H., additional, Sikes, David H., additional, Kawanchi, Ronald H., additional, Schlabach, Larry, additional, McCachren, Samuel Spence, additional, Cosgriff, Thomas M., additional, Dreisbach, Luke, additional, DeMichele, Angela, additional, Pawl, Lawrence, additional, Lucas, Jennifer, additional, Shinn, Lowell C., additional, Alkhouri, Nabiel, additional, Monga, Manish, additional, Lindquist, Deborah L., additional, Anderson, Thomas C., additional, Khurshid, Humera, additional, Witherby, Sabrina, additional, Erickson, Nicholette, additional, Traynor, Ann, additional, Bose, Ron, additional, Pluard, Timothy J., additional, Jones, Michael C., additional, Prakash, Sucharu, additional, Volterra, Fabio, additional, Capo, Gerardo, additional, Flaherty, Lawrence E., additional, Gartner, Elaina, additional, Baidas, Said, additional, Okazaki, Ian, additional, Nguyen, Bichlien, additional, Rakowski, Thomas, additional, Oliff, Ira, additional, Leach, Joseph W., additional, Anderson, Daniel, additional, Kubiak, Kendra, additional, Tsai, Michaela, additional, Vroman, Philippe, additional, Deleu, Ines, additional, Lybaert, Willem, additional, Borms, Marleen, additional, Couture, Felix, additional, Wilson, Jonathan J., additional, Hunt, Gordon, additional, Holland, David R., additional, Mingrone, Walter, additional, Wang, Shusen, additional, Liu, Donggeng, additional, Jiang, Zefei, additional, Benesova, Vera, additional, Smakal, Martin, additional, Garnolova, Petra, additional, Vesper, Anne-Sophie, additional, Neumann, Monika, additional, Janni, Wolfgang, additional, Liedtke, Cornelia, additional, Fischer, Dorothea, additional, Grischke, Eva-Maria, additional, Seeger, Dietmar, additional, Moebus, Volker, additional, Prechtl, Anita, additional, Carlos Camara Toral, Juan, additional, Sanchez Munoz, Alfonso, additional, Gonzalez Jimenez, Sonia, additional, Cassinello Espinosa, Javier, additional, Cirauqui, Beatriz, additional, Margeli Vila, Mireia, additional, Batista Lopez, Norberto, additional, Chacon Lopez-Muniz, Jose Ignacio, additional, de la Cruz Mora, Miguel Angel, additional, Mailliez, Audrey, additional, Vanlemmens, Laurence, additional, Pouessel, Damien, additional, Espie, Marc, additional, Conibear, John, additional, Roylance, Rebecca, additional, Harnett, Adrian, additional, 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additional, Martinez del Prado, Purificacion, additional, Machover, David, additional, Mayeur, Didier, additional, Trufflandier, Nathalie, additional, Delecroix, Valerie, additional, Mousseau, Mireille, additional, Mouret-Reynier, Marie-Ange, additional, Nabholtz, Jean-Marc, additional, Chetiyawardana, Anula D., additional, Papandreou, Christos, additional, Hornyak, Lajos, additional, Faluhelyi, Zsolt, additional, Simo, Erzsebet, additional, Di Palma, Mario, additional, Cognetti, Francesco, additional, Gorzegno, Gabriella, additional, Dogliotti, Luigi, additional, Gridelli, Cesare, additional, Falcone, Alfredo, additional, Soto Parra, Hector, additional, Buscarino, Calogero, additional, Im, Seock-Ah, additional, Sanchez Llamas, Benito, additional, Dercksen, Wouter, additional, Erdkamp, Franciscus, additional, Ruit, Jan B., additional, Braun, Hans, additional, Portielje, Joanneke E.A., additional, Ciltas, Aydin, additional, Buyukberber, Suleyman, additional, Benekli, Mustafa, additional, Zahalsky, Andrew J., additional, Jaslow, Rebecca, additional, Thomas, Gary W., additional, Maini, Archana, additional, Wiznitzer, Israel, additional, Khojasteh, Ali, additional, Francisco Gonzalez, Manuel, additional, Kong, Lynn R., additional, Padmanabhan, Aruna, additional, Conkright, William A., additional, Swain, Sandra M., additional, Faig, Douglas E., additional, Jain, Kirti, additional, Yanagihara, Ronald H., additional, Ottaviano, Yvonne, additional, Delmas, Andrew, additional, Steele, Heather A., additional, Rainey, Gordon K., additional, Harris, Penelope J., additional, Burris, Jason K., additional, Rupard, Erik J., additional, Tan, Esther, additional, Whitworth, Pat W., additional, Bova, Abby R., additional, Anderson, Ian C., additional, Shirinian, Mihran, additional, Tin-u, Caesar, additional, O'Rourke, Timothy J., additional, Roberts, Michael S., additional, Francisco, Michael, additional, Pierson, A. Scott, additional, Byeff, Peter D., additional, Kovach, Peter A., additional, Caton, John R., additional, Rarick, Mark Urban, additional, Schimidt, William G., additional, Stopeck, Alison T., additional, Swart, Rachel, additional, Carrillo Flores, Maria Regina, additional, Alemany, Carlos A., additional, Lozada, Brennely, additional, Weinstein, Paul L., additional, Wang, Wei, additional, Porubcin, Michael, additional, Ellison, David M., additional, Geils, George F., additional, Rivera, Edgardo, additional, and Charif, Mahmoud, additional

Published
2017
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40. Early-Onset Breast Cancer: Effect of Diagnosis and Therapy on Fertility Concerns, Endocrine System, and Sexuality of Young Mothers in Germany.

Author

Pursche, Telja, Bauer, Julia, Hammersen, Friederike, Rody, achim, Waldmann, annika, and Fischer, Dorothea

Subjects
BREAST tumor diagnosis, BREAST tumor treatment, AGE factors in disease, BREAST tumors, CANCER patient psychology, CANCER patient rehabilitation, FERTILITY, HEALTH education, HEALTH outcome assessment, HUMAN sexuality, TEENAGE mothers, ENDOCRINE system, FAMILY planning, DESCRIPTIVE statistics, FERTILITY preservation, ADOLESCENCE, PSYCHOLOGY
Abstract

Background: The purpose of this study was to analyze the effect of breast cancer therapy on fertility concerns and sexuality of young mothers with breast cancer in Germany. Methods: During a mother-child rehabilitation program, 1,191 young mothers with locoregional primary breast cancer, treated between 2006 and 2014, were recruited. Data included sociodemographic data, TNM stage, tumor biology, therapies, and patient-reported outcomes such as sexuality and fertility concerns. Results: The mean age at diagnosis was 40 years. Approximately a quarter of the patients stated that family planning had not been completed at the time of diagnosis. Nearly half of all patients had been informed as to how treatment could affect fertility, but counseling at a specialized fertility center was offered to only 13%. Of all patients, 4% took a consultation and 2% underwent fertility preservation procedures. Conclusion: Our study indicates that only a minority of patients is referred to fertility centers although family planning is incomplete at the time of diagnosis in about 25% of young women with breast cancer. Thus, these patients should not only be informed about the effects of treatment on fertility and sexuality, but should be referred to a fertility center. [ABSTRACT FROM AUTHOR]

Published
2019
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48. Effect of Luteinizing Hormone–Releasing Hormone Agonist on Ovarian Function After Modern Adjuvant Breast Cancer Chemotherapy: The GBG 37 ZORO Study

Author

Gerber, Bernd, primary, von Minckwitz, Gunter, additional, Stehle, Heinrich, additional, Reimer, Toralf, additional, Felberbaum, Ricardo, additional, Maass, Nikolai, additional, Fischer, Dorothea, additional, Sommer, Harald L., additional, Conrad, Bettina, additional, Ortmann, Olaf, additional, Fehm, Tanja, additional, Rezai, Mahdi, additional, Mehta, Keyur, additional, and Loibl, Sibylle, additional

Published
2011
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49. Expression of vitamin D receptor (VDR), cyclooxygenase-2 (COX-2) and 15-hydroxyprostaglandin dehydrogenase (15-PGDH) in benign and malignant ovarian tissue and 25-hydroxycholecalciferol (25(OH2)D3) and prostaglandin E2 (PGE2) serum level in ovarian cancer patients

Author

Thill, Marc, primary, Fischer, Dorothea, additional, Kelling, Katharina, additional, Hoellen, Friederike, additional, Dittmer, Christine, additional, Hornemann, Amadeus, additional, Salehin, Darius, additional, Diedrich, Klaus, additional, Friedrich, Michael, additional, and Becker, Steffi, additional

Published
2010
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