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6. Factors associated with disease-specific life impact in patients with hidradenitis suppurativa: results from the Global VOICE project

Author

Garg, Amit, primary, Rawal, Sahil, additional, Akilov, Oleg, additional, Alavi, Afsaneh, additional, Ardon, Christine, additional, Bechara, Falk G, additional, Cohen, Arnon D, additional, Cohen, Steven R, additional, Daveluy, Steven, additional, del Marmol, Véronique, additional, Delage, Maïa, additional, Esmann, Solveig, additional, Fisher, Shani, additional, Giamarellos-Bourboulis, Evangelos J, additional, Glowaczewska, Amelia, additional, Goldfarb, Noah, additional, Gonzalez Brant, Elena, additional, Grimstad, Øystein, additional, Guilbault, Sandra, additional, Hamzavi, Iltefat, additional, Hughes, Rosalind, additional, Ingram, John R, additional, Jemec, Gregor B E, additional, Ju, Qiang, additional, Kappe, Naomi, additional, Kirby, Brian, additional, Kirby, Joslyn S, additional, Lowes, Michelle A, additional, Matusiak, Lukasz, additional, Micha, Stella, additional, Micheletti, Robert G, additional, Miller, Angela P, additional, Moseng, Dagfinn, additional, Naik, Haley B, additional, Nassif, Aude, additional, Nikolakis, Georgios, additional, Paek, So Yeon, additional, Pascual, Jose Carlos, additional, Prens, Errol, additional, Resnik, Barry, additional, Riad, Hassan, additional, Sayed, Christopher, additional, Smith, Saxon D, additional, Soliman, Yssra, additional, Szepietowski, Jacek C, additional, Tan, Jerry, additional, Thorlacius, Linnea, additional, Tzellos, Thrasyvoulos, additional, van der Zee, Hessel H, additional, Villumsen, Bente, additional, Wang, Lanqi, additional, Zouboulis, Christos C, additional, and Strunk, Andrew, additional

Published
2023
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8. Factors associated with treatment satisfaction in patients with hidradenitis suppurativa: results from the Global VOICE project

Author

Midgette, Bria, primary, Strunk, Andrew, additional, Akilov, Oleg, additional, Alavi, Afsaneh, additional, Ardon, Christine, additional, Bechara, Falk G., additional, Cohen, Arnon D., additional, Cohen, Steven, additional, Daveluy, Steven, additional, del Marmol, Véronique, additional, Delage, Maïa, additional, Esmann, Solveig, additional, Fisher, Shani, additional, Giamarellos-Bourboulis, Evangelos J., additional, Glowaczewska, Amelia, additional, Goldfarb, Noah, additional, Brant, Elena Gonzalez, additional, Grimstad, Øystein, additional, Guilbault, Sandra, additional, Hamzavi, Iltefat, additional, Hughes, Rosalind, additional, Ingram, John R., additional, Jemec, Gregor B.E., additional, Ju, Qiang, additional, Kappe, Naomi, additional, Kirby, Brian, additional, Kirby, Joslyn S., additional, Lowes, Michelle A., additional, Matusiak, Lukasz, additional, Micha, Stella, additional, Micheletti, Robert, additional, Miller, Angela P., additional, Moseng, Dagfinn, additional, Naik, Haley, additional, Nassif, Aude, additional, Nikolakis, Georgios, additional, Paek, So Yeon, additional, Pascual, Jose Carlos, additional, Prens, Errol, additional, Resnik, Barry, additional, Riad, Hassan, additional, Sayed, Christopher, additional, Smith, Saxon D., additional, Soliman, Yssra, additional, Szepietowski, Jacek C., additional, Tan, Jerry, additional, Thorlacius, Linnea, additional, Tzellos, Thrasyvoulos, additional, van der Zee, Hessel H., additional, Villumsen, Bente, additional, Wang, Lanqi, additional, Zouboulis, Christos, additional, and Garg, Amit, additional

Published
2022
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10. Psoriasis and hidradenitis suppurativa: A large-scale population-based study.

Author

Kridin, Khalaf, Shani, Michal, Schonmann, Yochai, Fisher, Shani, Shalom, Guy, Comaneshter, Doron, Batat, Erez, and Cohen, Arnon D.

Abstract

The coexistence of psoriasis and hidradenitis suppurativa (HS) has been described, but the association between these conditions is yet to be firmly established. To study the association between psoriasis and HS by using a large-scale real-life computerized database. A cross-sectional study was conducted to compare the prevalence of HS among patients with psoriasis with that among age-, sex- and ethnicity-matched control subjects. A total of 68,836 patients with psoriasis and 68,836 controls were included in the study. The prevalence of HS was increased in patients with psoriasis versus in those in the control group (0.3% vs 0.2%, respectively; odds ratio, 1.8; 95% confidence interval, 1.5-2.3; P <.001). In a multivariate analysis adjusting for smoking, obesity, and other comorbidities, psoriasis was still associated with HS (odds ratio, 1.8; 95% confidence interval, 1.4-2.2; P <.001). Patients with coexistent psoriasis and HS were significantly younger (39.0 ± 15.7 vs 42.6 ± 21.2 years [ P =.015]) and had a higher prevalence of obesity (35.1% vs 25.3% [ P =.001]) and smoking (58.5% vs 37.3% [ P <.001]) compared with patients with psoriasis alone. Retrospective data collection. A positive association was observed between HS and psoriasis. Further longitudinal observational studies are necessary to establish these findings in other study populations. [ABSTRACT FROM AUTHOR]

Published
2023
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11. Chronic dermatoses exacerbation after COVID‐19 vaccination—A systematic review.

Author

Fisher, Shani, Dodiuk‐Gad, Roni P., and Ziv, Michael

Subjects
*COVID-19 vaccines, *SKIN diseases, *HIDRADENITIS suppurativa, *BOOSTER vaccines, *BULLOUS pemphigoid, *ERYTHEMA multiforme, *VITILIGO
Abstract

The coronavirus (COVID-19) pandemic led to a widespread use of vaccines that were approved based on their effectiveness against the virus. We performed a systematic review of the published literature to collect data regarding chronic dermatoses exacerbation after COVID-19 vaccination. Chronic dermatoses exacerbation after COVID-19 vaccination - A systematic review. [Extracted from the article]

Published
2023
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16. Evaluating patients' unmet needs in hidradenitis suppurativa: Results from the Global Survey Of Impact and Healthcare Needs (VOICE) Project

Author

Garg, Amit, primary, Neuren, Erica, additional, Cha, Denny, additional, Kirby, Joslyn S., additional, Ingram, John R., additional, Jemec, Gregor B.E., additional, Esmann, Solveig, additional, Thorlacius, Linnea, additional, Villumsen, Bente, additional, Marmol, Véronique del, additional, Nassif, Aude, additional, Delage, Maia, additional, Tzellos, Thrasyvoulos, additional, Moseng, Dagfinn, additional, Grimstad, Øystein, additional, Naik, Haley, additional, Micheletti, Robert, additional, Guilbault, Sandra, additional, Miller, Angie Parks, additional, Hamzavi, Iltefat, additional, van der Zee, Hessel, additional, Prens, Errol, additional, Kappe, Naomi, additional, Ardon, Christine, additional, Kirby, Brian, additional, Hughes, Rosalind, additional, Zouboulis, Christos C., additional, Nikolakis, Georgios, additional, Bechara, Falk G., additional, Matusiak, Lukasz, additional, Szepietowski, Jacek, additional, Glowaczewska, Amelia, additional, Smith, Saxon D., additional, Goldfarb, Noah, additional, Daveluy, Steven, additional, Avgoustou, Christina, additional, Giamarellos-Bourboulis, Evangelos, additional, Cohen, Steven, additional, Soliman, Yssra, additional, Brant, Elena Gonzalez, additional, Akilov, Oleg, additional, Sayed, Christopher, additional, Tan, Jerry, additional, Alavi, Afsaneh, additional, Lowes, Michelle A., additional, Pascual, José Carlos, additional, Riad, Hassan, additional, Fisher, Shani, additional, Cohen, Arnon, additional, Paek, So Yeon, additional, Resnik, Barry, additional, Ju, Qiang, additional, Wang, Lanqi, additional, and Strunk, Andrew, additional

Published
2020
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21. Healthcare Service Utilization by 116,816 Patients with Atopic Dermatitis in Israel.

Author

SHALOM, Guy, BABAEV, Meir, KRIDIN, Khalaf, SCHONMANN, Yochai, HOREV, Amir, DREIHER, Jacob, SHANI, Michal, TIOSANO, Shmuel, FISHER, Shani, COMANESHTER, Doron, and COHEN, Arnon D.

Subjects
ATOPIC dermatitis, MEDICAL databases, MEDICAL care, HOSPITAL emergency services, CONFIDENCE intervals
Abstract

Understanding of the epidemiology and healthcare service utilization related to atopic dermatitis is necessary to inform the use of new treatments. This cross-sectional study was based on a group of patients with atopic dermatitis and a matched control group comprised of age- and sex-matched enrolees without atopic dermatitis from a large medical database. Healthcare service utilization usage data were extracted and compared between groups. The study included 116,816 patients with atopic dermatitis and 116,812 controls. Atopic dermatitis was associated with an increased burden of healthcare utilization across the entire spectrum of healthcare services compared with controls. For patients severely affected by atopic dermatitis, the increased burden correlated with disease severity: a higher frequency of emergency room visits (odd ratio (OR) 1.7; 95% confidence interval (CI) 1.6-1.9), dermatology wards hospitalizations (OR 315; 95% CI 0-7,342), and overall hospitalizations (OR 3.6; 95% CI 3.3-3.9). In conclusion, this study demonstrates an increased burden of healthcare utilization in atopic dermatitis. [ABSTRACT FROM AUTHOR]

Published
2019
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23. [TRANSLATIONAL MEDICINE IN DERMATOLOGY- FURTHER PROMOTING PSORIASIS RESEARCH].

Author

Fisher S and Ziv M

Subjects
Humans, Translational Science, Biomedical, Skin, Cytokines, Dermatology, Psoriasis genetics, Psoriasis therapy
Abstract

Introduction: Psoriasis is a chronic inflammatory skin disorder that affects approximately 2-3% of the population worldwide. Translational medicine, which focuses on treating and analyzing diseases caused by translational factors, is becoming increasingly relevant in the field of psoriasis research. This review aims to display the current literature on the role of translational medicine in the treatment and understanding of psoriasis. We found that translational factors such as protein kinases and cytokines play a key role in the development and progression of psoriasis. Additionally, current treatments for psoriasis, such as biologics, target these translational factors to reduce inflammation and improve skin condition. Furthermore, studies have shown that genetic variations in translational-related genes can also contribute to the development of psoriasis. This highlights the importance of translational medicine in understanding the underlying mechanisms of psoriasis and developing increasingly effective treatments for this debilitating disease.

Published
2024

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