589 results on '"Fitzpatrick, Paul F."'
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2. An empirical analysis of enzyme function reporting for experimental reproducibility: Missing/incomplete information in published papers
3. Overview and Introduction
4. Metal dependence and branched RNA cocrystal structures of the RNA lariat debranching enzyme Dbr1
5. Cloning of Nitroalkane Oxidase from Fusarium oxysporum Identifies a New Member of the Acyl-CoA Dehydrogenase Superfamily
6. The aromatic amino acid hydroxylases: Structures, catalysis, and regulation of phenylalanine hydroxylase, tyrosine hydroxylase, and tryptophan hydroxylase
7. Combining solvent isotope effects with substrate isotope effects in mechanistic studies of alcohol and amine oxidation by enzymes
8. Thermodynamics of iron, tetrahydrobiopterin, and phenylalanine binding to phenylalanine hydroxylase from Chromobacterium violaceum
9. Archives of Biochemistry and Biophysics: 80th Anniversary
10. Measurement of Kinetic Isotope Effects in an Enzyme-Catalyzed Reaction by Continuous-Flow Mass Spectrometry
11. Substrate Specificities of Phenylalanine and Tyrosine Hydroxylase: Role of Aspartate 425 of Tyrosine Hydroxylase
12. Mechanistic Studies of Tryptophan Hydroxylase
13. Structures and mechanism of the monoamine oxidase family
14. Differential Quantum Tunneling Contributions in Nitroalkane Oxidase Catalyzed and the Uncatalyzed Proton Transfer Reaction
15. Alleviation of Catecholamine Inhibition of Tyrosine Hydroxylase by Phosphorylation at Serine40
16. Mechanistic Studies of Tyrosine Hydroxylase
17. Mechanistic and structural studies of H373Q flavocytochrome [b.sub.2]: Effects of mutating the active site base
18. 6 Amine and amino acid oxidases and dehydrogenases
19. Mechanistic studies of the flavoenzyme tryptophan 2-monooxygenase: Deuterium and [15.super.N] kinetic isotopes effects on alanine oxidation by an L-amino acid oxidase
20. Insights into the catalytic mechanisms of phenylalanine and tryptophan hydroxylase from kinetic isotope effects on aromatic hydroxylation
21. Reduction and oxidation of the active site iron in tyrosine hydroxylase: Kinetics and specificity
22. Crystal structures of nitroalkane oxidase: Insights into the reaction mechanism from a covalent complex of the flavoenzyme trapped during turnover
23. Effects of substitution at serine 40 of tyrosine hydroxylase on catecholamine binding
24. Probing the relative timing of hydrogen abstraction steps in the flavocytochrome b(sub)2 reaction with primary and solvent deuterium isotope effects and mutant enzymes
25. Reversing the substrate specificities of phenylalanine and tyrosine hydroxylase aspartate 425 of tyrosine hydroxylase is essential for L-DOPA formation
26. Mutation of serine 395 of tyrosine hydroxylase decouples oxygen-oxygen bond cleavage and tyrosine hydroxylation
27. pH and kinetic isotope effects
28. Inhibition studies and activation by imidazole
29. Identification of an essential tyrosine residue in nitroalkane oxidase by modification with tetranitromethane
30. Effects of phosphorylation on binding of catecholamines to tyrosine hydroxylase: specificity and thermodynamics
31. pH and deuterium isotope effects on the reaction of trimethylamine dehydrogenase with dimethylamine
32. The Aromatic Amino Acid Hydroxylases
33. Influence of steric bulk and electrostatics on the hydroxylation regiospecificity of tryptophan hydroxylase: characterization of methyltryptophans and azatryptophans as substrates
34. Phenylalanine residues in the active site of tyrosine hydroxylase: mutagenesis of Phe300 and Phe309 to alanine and metal ion-catalyzed hydroxylation of Phe300
35. Characterization of 2-oxo-3-pentynoate as an active-site-directed inactivator of flavoprotein oxidases: identification of active-site peptides in tryptophan 2-monooxygenase
36. Site-directed mutants of charged residues in the active site of tyrosine hydroxylase
37. Tetrahydropterin-dependent amino acid hydroxylases
38. Crystal structure of tyrosine hydroxylase at 2.3 Å and its implications for inherited neurodegenerative diseases
39. Mutation to phenylalanine of tyrosine 371 in tyrosine hydroxylase increases the affinity for phenylalanine
40. Pteridines
41. Effects of phosphorylation of serine 40 of tyrosine hydroxylase on binding of catecholamines: evidence for a novel regulatory mechanism
42. Oxygen-18 kinetic isotope effect studies of the tyrosine hydroxylase reaction: evidence of rate limiting oxygen activation
43. Biochemical and physical characterization of the active FAD-containing form of nitroalkane oxidase from Fusarium oxysporum
44. Characterization of chimeric pterin-dependent hydroxylases: contributions of the regulatory domains of tyrosine and phenylalanine hydroxylase to substrate specificity
45. Identification of native flavin adducts from Fusarium oxysporum using accurate mass matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
46. A mechanism for hydroxylation by tyrosine hydroxylase based on partitioning of substituted phenylalanines
47. Identification of tyrosine hydroxylase as a physiological substrate for Cdk5
48. Effects of phosphorylation by protein kinase A on binding of catecholamines to the human tyrosine hydroxylase isoforms
49. pH and kinetic isotope effects
50. Kinetic mechanism
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