Search

Your search keyword '"Florin Ştefan Olaru"' showing total 4 results
Start Over Author "Florin Ştefan Olaru"
4 results on '"Florin Ştefan Olaru"'

1. THE ROLE OF PSYCHOSOCIAL INTERVENTIONS IN THE REHABILITATION OF PATIENTS WITH SURGICAL INTERVENTIONS FOR ORAL CANCER

Author

Iulia Olaru, Florin-Ştefan Olaru, Alexandra Boloș, and Adriana Olaru

Subjects
psychosocial intervention, treatment, oral cancer, Dentistry, RK1-715
Abstract

The surgical interventions performed to treat oral cancer can cause important psychological manifestations, but also eating disorders, deglutition disorders, intense pain, sometimes severe depression or anxiety. That is why it is very important to understand as completely as possible the psychological and social deficiencies that patients diagnosed with oral cancer may encounter, in order to help them throughout the treatment, and throughout their survival. The implementation of measures to ensure the psychosocial adaptation to everything that involves a surgical intervention for the treatment of oral cancer needs to be done as early as possible. The goals of these interventions can be represented by the reduction of isolation, the feeling of alienation, anxiety, lack of hope and optimism regarding the future and the clarification or reinterpretation of erroneous information and thoughts about the disease and treatment. Accordingly, this work aims to highlight those measures that can be used to reduce the psychosocial consequences determined by the complex treatment and especially by the surgical intervention specific to oral cancer.

Published
2023

2. PSYCHOSOCIAL ASPECTS AND THE ROLE OF THE MULTIDISCIPLINARY TEAM IN THE DIAGNOSIS AND TREATMENT OF ORAL CANCER

Author

Iulia Olaru, Florin-Ştefan Olaru, Georgiana Macovei, and Alexandra Boloș

Subjects
oral cancer, treatment, mental manifestations., Dentistry, RK1-715
Abstract

Oral cancer is one of the most common malignancies in the world, Squamous Cell Carcinoma being the most common form at lips’ level. The treatment of oral cancer still remains a challenge for both doctors and patients. The quality of a person’s life is also influenced by oral health through the role that the oral cavity has in speech, nutrition, facial aesthetics and social acceptance. This paper aims to highlight the need for the involvement of a multidisciplinary team in the diagnosis and treatment of oral cancer, with the achievement of a complex assessment, including in terms of anxiety, social stressors, personality traits, coping resources or the diagnosis of even some possible mental disorders. Thus, the psychiatric evaluation of patients with oral cancer aims to coordinate and involve a psychiatric therapy in the complex oncological and surgical treatment of these patients.

Published
2023

3. The significance of erythropoietin and insulin administration on survival of fat tissue after autologous fat transplantation in Wistar rats. An experimental study

Author

Aurelian Sorin Paşca, Teodor Stamate, Camelia Tamas, Iulia Dabija Olaru, Gabriela Florenţa Dumitrescu, Anca Sava, Claudia Florida Costea, and Florin Ştefan Olaru

Subjects
Male, Embryology, medicine.medical_specialty, fat transplantation, insulin, Angiogenesis, medicine.medical_treatment, Urology, Adipose tissue, Transplantation, Autologous, Pathology and Forensic Medicine, chemistry.chemical_compound, Adipocyte, medicine, Animals, Rats, Wistar, Original Paper, business.industry, Insulin, Graft Survival, Cell Biology, General Medicine, lipofilling, Resorption, Rats, Transplantation, Autologous fat, chemistry, Adipose Tissue, Erythropoietin, free fat grafts, erythropoietin, business, Developmental Biology, medicine.drug
Abstract

Autologous fat transfer is widely used by plastic surgeons for aesthetic and reconstructive purpose, but it has a great disadvantage because of its high variability rate of resorption. Numerous studies have examined the use of different agents to increase the viability of fat grafts. The results were discouraging because the use of a single angiogenic factor to stimulate fat graft angiogenesis may be inappropriate. We proposed to use two pharmacological factors, erythropoietin (EPO) and insulin (INS), in order to decrease the resorption rate, to improve graft vascularization, and to reduce the number of complications. Twenty-four Wistar male rats were randomly divided in four groups (I-IV) of six animals each. The rats belonging to control group were given autologous transfer of simple fat. In group II, the graft was improved with EPO, in group III with INS, and in group IV both pharmacological agents were administered. Histological evaluation of the grafts at two months after injection demonstrated adipocyte survival in all four groups. The volume of the graft has progressively decreased in all groups and the difference in graft volume at one and two months after transplantation was not significant. The highest maintenance of fat graft volume (95%) at two months was observed in group IV, followed by group II and group III. Necrotic cystic changes and increased fibrosis were most extensive in the control group. The combination of INS with EPO may have a synergistic and additive effect. Efficient administration and dose optimization of these growth factors are important things to consider in the future.

Published
2021

4. Surgical reconstruction of post-tumoral facial defects

Author

Camelia, Tamaş, Cătălina Teodora, Pintilie, Ionuţ Vivi, Atănăsoae, Andreea Mioara, Corduneanu, Iulia, Dabija, Florin Ştefan, Olaru, Irina Mihaela, Hreniuc, Angela, Tecuceanu, Ioana, Munteanu, Costel, Dobre, Dan Cristian, Moraru, Victor, Ianole, Ioana, Tamaş, and Victor Vlad, Costan

Subjects
Male, Carcinoma, Squamous Cell, Humans, Female, Facial Neoplasms, Plastic Surgery Procedures, Retrospective Studies
Abstract

The face is an unfortunate location for any type of tumor - malignant or not - with significant esthetic and functional outcomes. To reconstruct a facial defect may seem simple, but can be rather complicated. The aim of this study is to analyze and discuss our results in order to conclude with specific surgical strategies correlated with the morphopathological results. The most important objective for us is to offer the highest level of expertise to our patients and to prove that the symbiosis between the surgical treatment and the work of the Department of Morphopathology is essential in order to maximize the quality of medical care provided for our patients.A retrospective study was conducted on 116 patients diagnosed with facial malignant tumors, 70 of which were confirmed as basal cell carcinomas (BCCs), 35 confirmed as squamous cell carcinomas (SCCs) and 11 malignant melanomas (MMs). Most BCC cases (57) showed ulceration, with a long clinical evolution (more than 10 years) in 48 cases. Only in 12 SCC cases, patients showed inflammation and ulceration, with a shorter evolution period (2-5 years). For complete microscopic diagnosis, immunohistochemical (IHC) examination was necessary in 46 cases. The BCC "deceiving" clinical behavior and the generally aggressive character of the MM were found in our patients as well.The most frequent sites were the orbital region (27 cases) and the nasolabial sulcus (26 cases). In order to reconstruct the postexcisional defects, we had to perform local flaps in 62 cases (14 frontal flaps for orbital defects, 32 glabellar flaps for medial epicanthus, lower lid and nasal region, 15 nasolabial flaps for lower lid or nasal alae and one "Z"-plasty for the submental region). Oncological follow-up was performed in all patients and in 15 cases re-excision was necessary (11 BCCs, two SCCs and two MMs). Cervical lymph node metastasis occurred in six cases (three BCCs, one SCC and two MMs).The cooperation between surgeons and pathologists allowed for good outcomes and the pathology examination can guide the surgical approach towards better results both functionally and esthetically.

Published
2018

Catalog

Books, media, physical & digital resources
See catalog results