Search

Your search keyword '"Fontana, Carolina"' showing total 264 results
Start Over Author "Fontana, Carolina"
264 results on '"Fontana, Carolina"'

2. Spontaneous ependymoma in a free-ranging juvenile black-horned capuchin (Sapajus nigritus).

Author

Fontana, Carolina, Ferronato, Amália, Dahm, Vinicius, Berón, Marina M., Wu, Stacy, Piccoli, Ronaldo J., de Carvalho, Anderson L., and de Marco Viott, Aline

Subjects
GLIAL fibrillary acidic protein, WILDLIFE conservation, SYMPTOMS, NERVOUS system, EPENDYMOMA
Abstract

A young free-ranging black-horned capuchin (Sapajus nigritus) with a history of ataxia, anisocoria, diminished threat and pupil reflexes and increased cranial circumference was referred for evaluation to the Medicine and Wildlife Conservation Section, Federal University of Paraná, Paraná, Brazil. Due to the clinical presentation and radiographic findings of hydrocephalus, euthanasia was performed. Necropsy revealed a dark red mass (1.5 × 1.8 cm) in the region of the third ventricle and marked dilation of the lateral ventricles. Histopathological findings were characterized by proliferation of ciliated round cells with eosinophilic cytoplasm, as well as the formation of ependymal rosettes and pseudorosettes. In some areas the cells contained brown cytoplasmic pigment, which stained with Fontana-Masson. The neoplastic cells were immunoreactive for glial fibrillary acidic protein and negative for pancytokeratin. Considering the anatomopathological and immunohistochemical findings, the diagnosis was ependymoma grade II with melanocytic features, which is the first report of this neoplasm in any member of the genus Sapajus. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

4. Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

Author

Aznar Muñoz, Esther, Gil Divasson, Pedro, González Muñiz, Patricia, Muñoz Aguirre, Clara, Díaz Menéndez, Marta, de la Calle Prieto, Fernando, Arsuaga Vicente, Marta, Trigo Esteban, Elena, Pérez Valero, Ignacio, de Miguel Buckley, Rosa, Cadiñaños Loidi, Julen, Diaz Pollan, Beatriz, Martín Carbonero, Luz, Ramos Ramos, Juan Carlos, Loeches Yagüe, Belén, Montejano Sánchez, Rocío, González García, Juan, García Rodríguez, Julio, Berenguer, Juan, Ramírez, Margarita, Gutiérrez, Isabel, Tejerina, Francisco, Aldámiz-Echevarría, Teresa, Díez, Cristina, Fanciulli, Chiara, Pérez-Latorre, Leire, Pinilla, Blanca, López, Juan Carlos, Such Diaz, Ana, Álvaro Alonso, Elena, Torres Macho, Juan, Cuevas Tascon, Guillermo, Jiménez González de Buitrago, Eva, Brañas Baztán, Fátima, Valencia de la Rosa, Jorge, Pérez Butragueño, Mario, Fernández Jiménez, Inés, Muñiz Nicolás, Gemma, Sepúlveda Berrocal, Antonia, Gato Díez, Alberto, Toledano Sierra, María Pilar, García Butenegro, María Paz, Peláez Ballesta, Ana Isabel, Morcillo Rodríguez, Elena, Fernández Romero, Isidoro, Peláez Ballesta, Cristina, Guirado Torrecillas, María Isabel, Goikoetxea Agirre, Josune, Bereciartua Bastarrica, Elena, Guio Carrión, Laura, Rodríguez Álvarez, Regino, Ibarrola Hierro, Marta, Pérez Hernández, Isabel A., Pérez Zapata, Inés, Román Soto, Sergio, Kallouchi, Mohamed, Domínguez Vicent, Juan Ramón, Silvariño Fernández, Rafae, Ugalde Espiñeira, Jon, Sanjuan López, Ainhoa, García Martínez, Silvia, Temprano Gogenola, Mikel, Asensi, Víctor, Suárez, Silvia, Suárez, Lucia, Yllera, Carmen, Rivas-Carmenado, María, Romero-Palacios, Alberto, Ruiz Aragón, Jesús, Jiménez Aguilar, Patricia, Fernández Ávila, Ma Luisa, Castilla Ortiz, Rosario, Alende Castro, Vanesa, Pérez García, Cristina, Fernández Morales, Marta, Valle Feijoo Begoña Rodríguez Ferreira, María Lorena María, Gómez-Junyent, Joan, Villar-García, Judit, López-Montesinos, Inmaculada, Arrieta-Aldea, Itziar, Rial-Villavecchia, Abora, García Vázquez, Elisa, Roura Piloto, Aychel Elena, Moral Escudero, Encarnación, Hernández Torres, Alicia, Albendín Iglesias, Helena, Vinuesa García, David, Martínez Montes, Clara, De la Hera Fernández, Francisco Javier, Anguita Santos, Francisco, Ruiz Sancho, Andrés, Díaz de Brito Fernández, Vicens, Sanmarti Vilamala, Montserrat, España Cueto, Sergio, Molina Morant, Daniel, González-Cuevas, Araceli, Chara Cervantes, Joel Elías, Policarpo Torres, Guillem, Ortega Montoliu, Meritxell, Angerri Nadal, Mònica, De Genover Gil, Ariadna, Patera, Eleni, Godoy Lorenzo, Rita, Zioga, Evangelia Anna María, Isern Fernández, Virginia, Sabbagh Fajardo, Carlos Enrique, Ferrer Ribera, Ana, Bea Serrano, Carlos, Oltra Sempere, Rosa, Vela Bernal, Sara, Albiol Viñals, Paloma, Pedromingo Kus, Miguel, Garcinuño, María Ángeles, Fiorante, Silvana, Pérez Pinto, Sergio, de la Vega, Alexandra, Fariñas Álvarez, María Carmen, González Rico, Claudia, Arnaiz de las Revillas, Francisco, Giménez, Teresa, Calvo, Jorge, Meije Castillo, Yolanda, Duarte Borges, Alejandra, Pareja Coca, Júlia, Clemente Presas, Mercedes, Sanz Salvador, Xavier, Pérez Rodríguez, Ma Teresa, Sousa, Adrián, Pérez González, Alexandre, Longueira, Rebeca, Araujo, Alejandro, Alonso Martínez, Blanca, García Escudero, Laura, Lidia Kamel Rey, Sara, Roa Alonso, David, Avilés Parra, Juan Pablo, Pelegrín Senent, Iván, Rouco Esteves Marques, Rosana, Raich Montiu, Laia, Souto Higueras, Jessica, Gálvez Bobadilla, Manuel Alejandro, Parra Ruiz, Jorge, Ramos Sesma, Violeta, Velasco Fuentes, Sara, García Pereña, Laura, Lluna Carrascosa, Alfonso, Gilaberte Reyzábal, Sergio, Liébana Gómez, Mónica, Salillas Hernando, Juan, Serrano Martínez, Alberto, Torralba González de Suso, Miguel, Martínez Martín, Patricia, Rábago Lorite, Isabel, González-Ruano Pérez, Patricia, Pérez-Monte Mínguez, Beatriz, García Flores, Ángeles, Comas Casanova, Pere, Martín Plata, Andrea, Santana Báez, Sergio Manuel, Sanz Peláez, Oscar, Mohamed Ramírez, Karim, Robaina Bordón, José María, Vílchez Rueda, Helem Haydeé, Riera Jaume, Melchor, Mut Ramon, Gemma, Gavalda Manso, Meritxell, Planas Bibiloni, Lluis, Castelo Corral, Laura, Ramos Merino, Lucía, Sánchez Vidal, Efrén, Rodríguez Mayo, María, Míguez Rey, Enrique, García de Lomas Guerrero, José M., De la Torre Lima, Javier, Correa Ruiz, Ana, Fernández Sánchez, Fernando, Jiménez-García, Nicolás, Sierra-Monzón, José Luis, Gracia-Tello, Borja, Hernández-Bonaga, María, Pellejero, Galadriel, Asín-Corrochano, Marta, Boix Palop, Lucia, Calbo, Esther, Badía, Cristina, Dietl, Beatriz, Lucía, Gómez, Domínguez-Castellano, Ángel, Ríos-Villegas, María José, del Toro, María D., Palacios Baena, Zaira R., Salamanca-Rivera, Elena, Marín, Elena, Almadana, Virginia, Pérez-Galera, Salvador, González-Iglesias, Luisa, Abelenda-Alonso, Gabriela, Álvarez-Pouso, Claudia, Escrihuela, Francesc, Gudiol, Carlota, Lorenzo-Esteller, Laia, Niubó, Jordi, Podzamczer, Daniel, Pujol, Miquel, Rombauts, Alexander, Salvert Lletí, Miguel, Gil Sánchez, Ricardo, Jiménez Escrig, Marta, Parra Gómez, Laura, Tasias Pitarch, Mariona, Navarro Vilasaró, Marta, Machado Sicilia, María Luisa, Gomila Grange, Aina, Calzado Isbert, Sonia, Carrasco Antón, Nerea, Petkova-Saiz, Elizabet, Cabello Úbeda, Alfonso, Górgolas Hernández-Mora, Miguel, Sánchez-Pernaute, Olga, Dueñas Gutiérrez, Carlos, Martin Guerra, Javier, Castrodeza Sanz, José Javier, Fernández Espinilla, Virginia, Rodríguez Fernández, Laura, González-Moreno, Juan, Villoslada Gelabert, Aroa, Ribot Sanso, María Antonia, Fernández-Baca, María Victoria, Hernández Milian, Almudena, Morán Rodríguez, Miguel Ángel, Ortiz de Zárate Ibarra, Zuriñe, Portu Zapirain, José Joaquin, Saez de Adana Arroniz, Ester, Gainzarain Arana, Juan Carlos, Meca Birlanga, Olga, del Amor Espín, Ma Jesús, Viqueira González, Montserrat, García García, Josefina, Martínez Madrid, Onofre, Bernal Morell, Enrique, Alcaraz, Antonia, Muñoz, Ángeles, Pina, Ignacio, de la Rosa, Vicente, Caínzos Romero, Tamara, Sánchez Trigo, Sabela, Mariño Callejo, Ana Isabel, Álvarez Díaz, Hortensia, Valcarce Pardeiro, Nieves, Sánchez Serrano, Adriana, Piñar Cabezos, Diana, García Villalba, Eva Pilar, Aguayo Jiménez, Carmen, Ruíz Campuzano, María, Naranjo Velasco, Virginia, Santos Peña, Marta, Mora Delgado, Juan, Sevilla Moreno, Israel, Lojo Cruz, Cristina, Kortajarena Urkola, Xabier, Iribarren Loyarte, José Antonio, Bustinduy Odriozola, María Jesús, Ibarguren Pinilla, Maialen, Álvarez Rodríguez, Ignacio, Martínez Marcos, Francisco Javier, Rodríguez Gómez, Francisco Javier, Asschert Agüero, Isabel, Muñoz Beamud, Francisco, Ruiz Reina, Antonio José, Llenas-García, Jara, González-Cuello, Inmaculada, Hellín-Valiente, Elena, Martínez Birlanga, Esther, Tafalla Torres, José Manuel, Calderón Parra, Jorge, Escudero López, Gabriela, Gutiérrez Martín, Isabel, Andrés Eisenhofer, Ane, García Prieto, Sonia, Álvarez Franco, Raquel, Roger Zapata, Daniel, Martínez Cifre, Blanca, Aranda Rife, Elena, Martín Rubio, Irene, Barbosa Ventura, André, Garrido, Javier, Gonzalo, Concepción, Piñero, Iván, de la Cruz Felipe, Nieves, Talavera García, Eva, Lamata Subero, Marta, Mendoza Roy, Paula, García de Carlos, María Soledad, Lajusticia Aisa, Justo, Arteche Eguizabal, Lorea, Urrutia Losada, Ainhoa, Domingo Echaburu, Saioa, Cuadros Tito, Pedro Ángel, Orbe Narváez, Gurutz, Liébana Martos, Ma del Carmen, Roldán Fontana, Carolina, Herrero Rodríguez, Carmen, Duro Ruiz, Gaspar, Pérez Parra, Santiago, Mera Fidalgo, Arantzazu, Hortos Alsina, Miquel, Alberich Conesa, Ana, Bladé Vidal, Lourdes, Merchante Gutiérrez, Nicolás, León Jiménez, Eva, Espíndola Gómez, Reinaldo, Erostarbe Gallardo, María, Martínez Pérez-Crespo, Pedro, Cisneros, José Miguel, Aguilar-Guisado, Manuela, Aldabó, Teresa, Bueno, Claudio, Cordero-Matía, Elisa, Escoresca, Ana, Infante, Carmen, Guillermo, Martín, Salto, Sonsoles, Gioia, Francesca, Vizcarra, Pilar, Fortún Abete, Jesús, Martín Dávila, Pilar, Moreno Guillén, Santiago, Oteo Revuelta, José A., García-García, Concepción, Santibañez Sáenz, Paula, Cervera Acedo, Cristina, Azcona Gutiérrez, José M., Reguera Iglesias, José María, Plata Ciezar, Antonio, Valiente de Santis, Lucia, Sobrino Diaz, Beatriz, Ruiz Mesa, Juan Diego, Rodríguez-Baño, Jesús, Pachón, Jerónimo, Carratalà, Jordi, Ryan, Pablo, Jarrín, Inmaculada, Yllescas, María, and Arribas, José Ramón

Published
2021
Full Text
View/download PDF

5. Characteristics and predictors of death among 4035 consecutively hospitalized patients with COVID-19 in Spain

Author

Aznar Muñoz, Esther, Gil Divasson, Pedro, González Muñiz, Patricia, Muñoz Aguirre, Clara, López, Juan Carlos, Ramírez-Schacke, Margarita, Gutiérrez, Isabel, Tejerina, Francisco, Aldámiz-Echevarría, Teresa, Díez, Cristina, Fanciulli, Chiara, Pérez-Latorre, Leire, Parras, Francisco, Catalán, Pilar, García-Leoni, María E., Pérez-Tamayo, Isabel, Puente, Luis, Cedeño, Jamil, Berenguer, Juan, Díaz Menéndez, Marta, de la Calle Prieto, Fernando, Arsuaga Vicente, Marta, Trigo Esteban, Elena, Lago Núñez, Mª del Mar, de Miguel Buckley, Rosa, Cadiñaños Loidi, Julen, Busca Arenzana, Carmen, Mican, Alfredo, Mora Rillo, Marta, Ramos Ramos, Juan Carlos, Loeches Yagüe, Belén, Bernardino de la Serna, José Ignacio, García Rodríguez, Julio, Arribas López, José Ramón, Such Diaz, Ana, Álvaro Alonso, Elena, Izquierdo García, Elsa, Torres Macho, Juan, Cuevas Tascon, Guillermo, Troya García, Jesús, Mestre Gómez, Beatriz, Jiménez González de Buitrago, Eva, Fernández Jiménez, Inés, Tebar Martínez, Ana Josefa, Brañas Baztán, Fátima, Valencia de la Rosa, Jorge, Pérez Butragueño, Mario, Alvarado Blasco, Marta, Ryan, Pablo, Sepúlveda Berrocal, Mª Antonia, Yera Bergua, Carmen, Toledano Sierra, Pilar, Cano Llorente, Verónica, Zafar Iqubal-Mirza, Sadaf, Muñiz, Gema, Martín Pérez, Inmaculada, Mozas Moriñigo, Helena, Alguacil, Ana, García Butenegro, María Paz, Peláez Ballesta, Ana Isabel, Morcillo Rodríguez, Elena, Goikoetxea Agirre, Josune, Blanco Vidal, María José, Nieto Arana, Javier, del Álamo Martínez de Lagos, Mikel, Pérez Hernández, Isabel A., Pérez Zapata, Inés, Silvariño Fernández, Rafael, Ugalde Espiñeira, Jon, Asensi Álvarez, Víctor, Suárez Pérez, Lucia, Suárez Diaz, Silvia, Yllera Gutiérrez, Carmen, Boix, Vicente, Díez Martínez, Marcos, Carreres Candela, Melissa, Gómez-Ayerbe, Cristina, Sánchez-Lora, Javier, Velasco Garrido, José Luis, López-Jódar, María, Santos González, Jesús, Ruiz Aragón, Jesús, Virto Peña, Ianire, Alende Castro, Vanessa, Brea Aparicio, Ruth, Vega Molpeceres, Sonia, Pons Viñas, Estel, del Río Pérez, Oscar, Valero Rovira, Silvia, Villar-García, Judit, Gómez-Junyent, Joan, Knobel, Hernando, Cánepa, María Cecilia, Castañeda Espinosa, Silvia, Sorli Redò, Luisa, Güerri-Fernández, Roberto, Milagro Montero, María, Horcajada, Juan Pablo, García Vázquez, Elisa, Moral Escudero, Encarnación, Hernández Torres, Alicia, García Almodóvar, Esther, Sáez Barberá, Carmen, Karroud, Zineb, Hernández Quero, José, Vinuesa García, David, García Fogeda, José Luis, Peregrina, José Antonio, Novella Mena, María, Hernández Gutiérrez, Cristina, Sanz Moreno, José, Pérez Tanoira, Ramón, Sierra Rodríguez, Rodrigo, Alonso Menchén, David, Gutiérrez García, Aida, Arranz Caso, Alberto, Cuadros González, Juan, Álvarez de Mon Soto, Melchor, Díaz de Brito Fernández, Vicente Ferrer, Sanmarti Vilamala, Montserrat, Gabarrell Pascuet, Aina, Molina Morant, Daniel, España Cueto, Sergio, Cámara Fernández, Jonathan, Sabater Gil, Albert, Muñoz López, Laura, Sáez Escolano, Paula, Bejarano Tello, Esperanza, Sempere Alcocer, Marco Antonio, Álvarez Martin, Salvador, De los Santos Gil, Ignacio, García-Fraile, Lucio, Sampedro Núñez, Miguel, Barrios Blandino, Ana, Rodríguez Franco, Carlos, Useros Brañas, Daniel, Villa Martí, Almudena, Oliver Ortega, Javier, Costanza Espiño Álvarez, Alexia, Sanz Sanz, Jesús, Rexach Fumaña, María, Abascal Cambras, Ivette, Pérez Jaén, Ana del Cielo, Sala Jofre, Clara, Casas Rodríguez, Susana, Tortajada Alamilla, Cecilia, Oltra, Carmina, Masiá Canuto, Mar, Gutiérrez Rodero, Félix, Ferrer Ribera, Ana, Bea Serrano, Carlos, Pedromingo Kus, Miguel, Garcinuño, María Ángeles, Fiorante, Silvana, Pérez Pinto, Sergio, Hernández Machín, Pilar, Alastrué Violeta, Alba, Fariñas Álvarez, María Carmen, González Rico, Claudia, Arnaiz de las Revillas, Francisco, Calvo, Jorge, Gozalo, Mónica, Mora Gómez, Francisco, Milagro Beamonte, Ana, Latorre-Millán, Miriam, Rezusta López, Antonio, Martínez Sapiña, Ana, Meije, Yolanda, Duarte Borges, Alejandra, Pareja Coca, Julia, Clemente Presas, Mercedes, Losa García, Juan Emilio, Vegas Serrano, Ana, Pérez-Rodríguez, M. Teresa, Pérez González, Alexandre, Belhassen-García, Moncef, Rodríguez-Alonso, Beatriz, López-Bernus, Amparo, Carbonell, Cristina, Torres Perea, Rafael, Cantón de Seoane, Juan, Alonso, Blanca, Kamal, Sara Lidia, Cajuela, Lucia, Roa, David, Cervero, Miguel, Oreja, Alberto, Avilés, Juan Pablo, Martín, Lidia, Pelegrín Senent, Iván, Rouco Esteves Marques, Rosana, Parra Ruiz, Jorge, Ramos Sesma, Violeta, Abadia Otero, Jessica, Salillas Hernando, Juan, Torres Sánchez del Arco, Robert, Torralba González de Suso, Miguel, Serrano Martínez, Alberto, Gilaberte Reyzábal, Sergio, Pacheco Martínez-Atienza, Marina, Liébana Gómez, Mónica, Fernández Rodríguez, Sara, Varela Plaza, Álvaro, Calvo Sánchez, Henar, Martínez Martín, Patricia, González- Ruano, Patricia, Malmierca Corral, Eduardo, Rábago Lorite, Isabel, Pérez-Monte Mínguez, Beatriz, García Flores, Ángeles, Comas Casanova, Pere, Sirisi, Merce, Rojas, Richard, Díaz de Tuesta del Arco, José Luis, Figueroa Cerón, Ruth, González Sarria, Ander, Alemán Valls, Remedios, Alonso Socas, María del Mar, Sanz Peláez, Oscar, Mohamed Ramírez, Karim, Riera Jaume, Melchor, Vilchez, Helem Haydee, Albertí, Francesc, Cañabate, Ana Isabel, Moreno Cuerda, Víctor J., Álvarez Kaelis, Silvia, Álvarez Zapatero, Beatriz, García García, Alejandro, Isaba Ares, Elena, Morcate Fernández, Covadonga, Pérez Rodríguez, Andrea, Ramos Merino, Lucía, Castelo Corral, Laura, Rodríguez Mahía, María, González Bardanca, Mónica, Sánchez Vidal, Efrén, Míguez Rey, Enrique, De la Torre Lima, Javier, García de Lomas Guerrero, José Mª, Morte, Elena, Loscos, Silvia, Camón, Ana, Gómez García, Lucía, Boix Palop, Lucia, Dietl Gómez-Luengo, Beatriz, Pedrola Gorrea, Iris, Blasco Claramunt, Amparo, López Mestanza, Cristina, Fraile Villarejo, Esther, Tosco Núñez, Tomás, Aroca Ferri, María, Algado Rabasa, José Tomas, Garijo Saiz, Ana María, Amador Prous, Concepción, Baño, Jesús Rodriguez, Retamar, Pilar, Valiente, Adoración, López-Cortés, Luis E., Sojo, Jesús, Gutiérrez-Gutiérrez, Belén, Bravo-Ferrer, José, Salamanca, Elena, Palacios, Zaira R., Pérez-Palacios, Patricia, Peral, Enrique, Pérez de León, José Antonio, Sánchez-Gómez, Jesús, Marín-Barrera, Lucía, García-Jiménez, Domingo, Carratalà, Jordi, Abelenda-Alonso, Gabriela, Ardanuy, Carmen, Bergas, Alba, Cuervo, Guillermo, Domínguez, María Ángeles, Fernández-Huerta, Miguel, Gudiol, Carlota, Lorenzo-Esteller, Laia, Niubó, Jordi, Pérez-Recio, Sandra, Podzamczer, Daniel, Pujol, Miquel, Rombauts, Alexander, Trullen, Núria, Salavert Lletí, Miguel, Castro Hernández, Iván, Hernández Belmonte, Adriana, Martínez Goñi, Raquel, Navarro Vilasaró, Marta, Calzado Isbert, Sonia, Cervantes García, Manuel, Gomila Grange, Aina, Gasch Blasi, Oriol, Machado Sicilia, María Luisa, Van den Eynde Otero, Eva, Falgueras López, Luis, Navarro Sáez, María del Carmen, Martínez, Esteban, Marcos, Mª Ángeles, Mosquera, Mar, Blanco, José Luis, Laguno, Montserrat, Rojas, Jhon, González-Cordón, Ana, Inciarte, Alexy, Torres, Berta, De la Mora, Lorena, Soriano, Alex, Martínez Macias, Olalla, Pérez Doñate, Virginia, Cabello Úbeda, Alfonso, Carrasco Antón, Nerea, Álvarez Álvarez, Beatriz, Petkova Saiz, Elizabet, Górgolas Hernández-Mora, Miguel, Prieto Pérez, Laura, Carrillo Acosta, Irene, Heili Frades, Sara, Villar Álvarez, Felipe, Fernández Roblas, Ricardo, Milicua Muñoz, José María, Fernández Espinilla, Virginia, Dueñas Gutiérrez, Carlos Jesús, Hernán García, Cristina, González-Romo, Fernando, Merino Amador, Paloma, Rueda López, Alba, Martínez Jordán, Jorge, Medrano Pardo, Sara, Díaz de la Torre, Irene, Posada Franco, Yolanda, Delgado-Iribarren, Alberto, López-Contreras González, Joaquín, Pascual Alonso, Pablo, Pomar Solchaga, Virginia, Rabella García, Nuria, Benito Hernández, Natividad, Domingo Pedrol, Pere, Bonfill Cosp, Xavier, Padrós Selma, Rafael, Puig Campmany, Mireia, Mancebo Cortés, Jordi, Gurguí Ferrer, Mercè, Íñigo Pestaña, Melania, Pérez García, Alejandra, Sorní Moreno, Patricia, Izko Gartzia, Nora, Membrillo de Novales, Francisco Javier, Simón Sacristán, María, Zamora Cintas, Maribel, Martínez Martínez, Yolanda, Fernández-González, Pablo, Alcántara Nicolás, Francisco, Aguirre Vila-Cora, Alejandro, López Tizón, Elena, Ramírez-Olivencia, Germán, Estébanez Muñoz, Miriam, Sáez de Adana Arróniz, Ester, Portu Zapirain, Joseba, Gainzarain Arana, Juan Carlos, Ortiz de Zárate Ibarra, Zuriñe, Moran Rodríguez, Miguel Ángel, Canut Blasco, Andrés, Hernáez Crespo, Silvia, Balerdi Sarasola, Leire, Morales García, Cristina, Corral Saracho, Miguel, Valcarce González, Zeltia, Arenal Andrés, Noelia, Rodríguez Tarazona, Raquel Elisa, Iglesias Llorente, Laura, Loureiro Rodríguez, Beatriz, Sánchez Montalvá, Adrián, Espinosa Pereiro, Juan, Almirante, Benito, Miarons, Marta, Sellarés, Júlia, Larrosa, María, García, Sonia, Marzo, Blanca, Villamarín, Miguel, Fernández, Nuria, Pérez-Jorge Peremarch, Conchita, Resino Foz, Elena, Espigares Correa, Andrea, Álvarez de Espejo Montiel, Teresa, Navas Clemente, Iván, Quijano Contreras, María Isabel, Nieto Fernández del Campo, Luis Alberto, Jiménez Álvarez, Guillermo, Guillamón Sánchez, Mercedes, García García, Josefina, Muñoz Hornero, Constanza, Mariño Callejo, Ana, Valcarce Pardeiro, Nieves, Smithson Amat, Alex, Chico Chumillas, Cristina, Sánchez Serrano, Adriana, García Villalba, Eva Pilar, Jiménez Martínez, Isabel, Estrada Fernández, Guillermo, Lorén Vargas, María, Parra Arribas, Nuria, Martínez Cilleros, Carmen, Villasante de la Puente, Aránzazu, García Delange, Teresa, Ruiz Rodríguez, María José, Robledo del Prado, Marta, Abad Almendro, Juan Carlos, Muñoz del Rey, José Román, Jiménez Álvaro, Montaña, Coy Coy, Javier, Poquet Catala, Inmaculada, Santos Peña, Marta, Naranjo Velasco, Virginia, Manso Gómez, Tamara, Quilez Ágreda, Delia, Barbeito Castiñeiras, Gema, Domínguez Santalla, María Jesús, Mao Martín, Laura, Alonso Navarro, Rodrigo, Ampuero Martinich, Jose David, Barrós González, Raquel, Galindo Martín, María Aránzazu, Herrera Pacheco, Lourdes, Martínez Avilés, Rocío, Rodrigo González, Sara, Rodríguez Leal, Cristóbal Manuel, Romay Lema, Eva María, Suárez Gil, Roi, Ibarguren Pinilla, Maialen, Marimón Ortiz de Zárate, José María, Vidaur Tello, Loreto, Kortajarena Urkola, Xabier, García Gómez, Miriam, Aranguren Arostegui, Asier, Álvarez de Castro, Maria, Martínez Mateu, Cintia María, Rodríguez Gómez, Francisco, Muñoz Beamud, Francisco, Chamarro Martí, Elena, Cardona Rivera, Merce, Zakariya-Yousef Breval, Ismail, Rico Rodríguez, Marta, Llenas García, Jara, Sánchez Arenas, Mª Carmen, Fernández Cruz, Ana, Calderón Parra, Jorge, López Dosil, Marcos, Ramos Martínez, Antonio, Múñez Rubio, Elena, Callejas Díaz, Alejandro, Vázquez Comendador, José Manuel, Diego Yagüe, Itziar, Expósito Palomo, Esther, Anel Pedroche, Jorge, Álvarez Franco, Raquel, Fernández de Orueta, Lucía, Vates Gómez, Roberto, Cardona Arias, Andrés Felipe, Marguenda Contreras, Pablo, Gaspar Alonso-Vega, Gabriel, Aranda Rife, Elena María, Martínez Cifre, Blanca, Roger Zapata, Daniel, Martín Rubio, Irene, Barbosa Ventura, André, Piñero, Iván, Bahamonde Carrasco, Alberto, Runza Buznego, Paula, Talavera García, Eva, Lamata Subero, Marta, Urrutia Losada, Ainhoa, Arteche Eguizabal, Lorea, Delgado Sánchez, Elisabet, Molina Peinado, Virginia, Caro Bragado, Sarah, Domínguez de Pablos, Gema, Roldán Fontana, Carolina, Herrero Rodríguez, Carmen, Force Sanmartín, Luis, Aranega, Raquel, Mera Fidalgo, Arantzazu, Toda Savall, María Roca, Merchante Gutiérrez, Nicolas, León Jiménez, Eva María, Del Pozo, José Luís, Serralta Buades, Josefa, Cabrera Tejada, Ginger Giorgiana, Fernández-Ruiz, Mario, Aguado, José María, Maestro de la Calle, Guillermo, Cisneros, José Miguel, Pachón, Jerónimo, Aguilar-Guisado, Manuela, Aldabó, Teresa, Avilés, María Dolores, Bueno, Claudio, Cordero-Matía, Elisa, Escoresca, Ana, Gálvez-Benítez, Lydia, Infante, Carmen, Martín, Guillermo, Praena, Julia, Roca, Cristina, Salamanca, Celia, Suárez-Benjumea, Alejandro, Vizcarra, Pilar, Quereda, Carmen, Rodriguez Dominguez, Mario José, Gioia, Francesca, Norman, Francesca, Del Campo, Santos, Cantón Moreno, Rafael, Oteo Revuelta José, Antonio, Santibáñez Sáenz, Paula, Cervera Acedo, Cristina, Ruiz Martínez, Carlos, Blanco Ramos, José R., Azcona Gutiérrez, José M., García García, Concepción, Alba Fernández, Jorge, Ibarra Cucalón, Valvanera, San Franco, Mercedes, Metola Sacristán, Luis, Meijide Míguez, Héctor, Paulos Viñas, Silvia, Menéndez, Justo, Villares Fernández, Paula, Montes Andújar, Lara, Navarro Batet, Álvaro, Ferrer Santolaria, Anna, Padilla Salazar, María de la Luz, Abella Vázquez, Lucy, Hayek Peraza, Marcelino, García Pardo, Antonio, Hernández Carballo, Carolina, Ruiz Fernández, Andrés Javier, Barrio López, Isabel, Martakoush, Alí, Rojas-Vieyra, Agustín, García Calvo, Sonia, Villarreal García-Lomas, Mercedes, Vizcaíno Callejón, Marta, García García, María Pilar, Lérida Urteaga, Ana, Carrasco Fons, Natalia, María Sanjuan, Beatriz, Martín González, Lydia, Sanz Zamudio, Camilo, Jarrín, Inmaculada, Alejos, Belén, Moreno, Cristina, Rava, Marta, Iniesta, Carlos, Izquierdo, Rebeca, Suárez-García, Inés, Díaz, Asunción, Ruiz-Alguero, Marta, Hernando, Victoria, Rodríguez-Baño, Jesús, Yllescas, María, and Arriba, José Ramón

Published
2020
Full Text
View/download PDF

6. Evolución de la resistencia antimicrobiana en aislados clínicos de Pseudomonas aeruginosa productores de infecciones invasivas en el sur de España

Author

Garduño, Eugenio, Hernández Pérez, Purificación, Muñoz Sanz, José Román, González Velasco, Carmen, Rodríguez, Saray, Navarro Marí, José M., Dolores Rojo Martín, María, Álvarez Estévez, Marta, Peña Monje, Alejandro, Sánchez Yebra, Waldo, Roldán Fontana, Carolina, Martín Hita, Lina, Clavijo Frutos, Encarnación, Gracia Ortega, María, Palop Borrás, Begoña, Bermúdez Ruiz, Pilar, Antonio Lepe, José, Aznar, Javier, Carmen Domínguez, M., Gracia Ahufinger, Irene, Rodríguez, Fernando, Domínguez Castaño, Ana, Rodríguez Iglesias, Manuel, Galán Sánchez, Fátima, Dolores López Prieto, M., Sánchez Calvo, Juan Manuel, López Barba, José Luis, Martínez Rubio, Carmen, Fernández-Cuenca, Felipe, Martínez-Martínez, Luis, and Pascual, Álvaro

Published
2020
Full Text
View/download PDF

15. Eficiência do protocolo de fermentação em cama de aviário para controle de salmonela

Author

Lima, Rafaela and Fontana, Carolina

Abstract

Em 2021 o Brasil alcançou a terceira posição mundial na produção de carne de frango com 14.500 milhões de toneladas de carne e foi o país que mais exportou seus produtos. Devido a presença de fezes de aves infectadas em cama de aviário, a salmonela pode ser encontrada. A prevenção envolve a prática de higiene e biossegurança nas instalações de criação, como limpeza e desinfecção dos galpões e equipamentos utilizados durante a produção de um lote. A fermentação em cama é uma técnica incentivada e permitida pelo Ministério da Agricultura, Pecuária e Abastecimento (MAPA) descrita na Instrução Normativa n° 56 de 04 de dezembro de 2007, é um processo biológico que tem como objetivo reduzir a carga parasitária na cama afim de reutilizá-la. Esse descreve a identificação da presença de salmonelas e a eficiência do procedimento de fermentação biológica de camas de aviário de 156 granjas da região oeste do Paraná. Entre os meses de Junho de 2021 à dezembro de 2022 foram identificados 156 aviários positivos para salmonela aos 21 dias de vida do pintainho. Após a saída do lote os mesmos seguiram o protocolo fermentação e rebaixamento de cama fornecido pela integradora, posterior ao processo realizado no intervalo, foi realizada uma nova coleta de swab de arrasto para análise de salmonela onde 154 granjas evidenciaram laudos negativos e o procedimento eficiente na redução da bactéria.

Published
2023
Full Text
View/download PDF

16. Primary Structure of Glycans by NMR Spectroscopy

Author

Fontana, Carolina, Widmalm, Göran, Fontana, Carolina, and Widmalm, Göran

Abstract

Glycans, carbohydrate molecules in the realm of biology, are present as biomedically important glycoconjugates and a characteristic aspect is that their structures in many instances are branched. In determining the primary structure of a glycan, the sugar components including the absolute configuration and ring form, anomeric configuration, linkage(s), sequence, and substituents should be elucidated. Solution state NMR spectroscopy offers a unique opportunity to resolve all these aspects at atomic resolution. During the last two decades, advancement of both NMR experiments and spectrometer hardware have made it possible to unravel carbohydrate structure more efficiently. These developments applicable to glycans include, inter alia, NMR experiments that reduce spectral overlap, use selective excitations, record tilted projections of multidimensional spectra, acquire spectra by multiple receivers, utilize polarization by fast-pulsing techniques, concatenate pulse-sequence modules to acquire several spectra in a single measurement, acquire pure shift correlated spectra devoid of scalar couplings, employ stable isotope labeling to efficiently obtain homo- and/or heteronuclear correlations, as well as those that rely on dipolar cross-correlated interactions for sequential information. Refined computer programs for NMR spin simulation and chemical shift prediction aid the structural elucidation of glycans, which are notorious for their limited spectral dispersion. Hardware developments include cryogenically cold probes and dynamic nuclear polarization techniques, both resulting in enhanced sensitivity as well as ultrahigh field NMR spectrometers with a 1H NMR resonance frequency higher than 1 GHz, thus improving resolution of resonances. Taken together, the developments have made and will in the future make it possible to elucidate carbohydrate structure in great detail, thereby forming the basis for understanding of how glycans interact with other molecules.

Published
2023
Full Text
View/download PDF

23. Uso da hibridização fluorescente in situ (FISH) para detecção de Chlamydia sp. em aves silvestres

Author

Fontana, Carolina, 1994, Universidade Federal do Paraná. Setor Palotina. Programa de Pós-Graduação em Ciência Animal, and Viott, Aline de Marco, 1981

Subjects
Zoonoses, Clamidioses, Ornitopatologia
Abstract

Orientadora: Profa. Dra. Aline de Marco Viott Dissertação (mestrado) - Universidade Federal do Paraná, Setor Palotina, Programa de Pós-Graduação em Ciência Animal. Defesa : Curitiba, 29/03/2022 Inclui referências Resumo: A clamidiose aviária é uma doença bacteriana de grande importância tanto para espécies aviárias quanto para o ser humano, levantando a necessidade de estabelecimento de diagnóstico rápido e efetivo para detecção das bactérias do gênero Chlamydia, causadoras da doença. O presente trabalho objetiva descrever a detecção de Chlamydia sp. por meio da técnica de hibridização fluorescente in situ (FISH) em cortes histológicos de pulmão, baço e segmentos de intestino de pombos-comuns (Columba livia), fixados em formol 10%. Amostras de 74 pombos-comuns foram avaliados pela técnica FISH e por histopatologia convencional; A sonda utilizada seguiu uma sequência de 20 bases para anelamento, correspondente ao gene codificados das MOMP (Major Outer Membrane Protein) das bactérias do gênero Chlamydia, e acrescida do fluorocromo Alexa Fluor 555®. A histopatologia evidenciou predominantemente enterite linfohistiocitária e/ou granulocítica, e serosite/miosite linfohistiocitária em 28,1% dos intestinos. Esplenite granulomatosa e linfohistiocitária, perivasculite, e áreas multifocais de necrose, distribuídas em 78,4% das amostras de baço avaliadas; Em pulmão foram observados quadros de pneumonia linfohistiocitária e/ou granulocítica, perivasculite linfohistiocitária em 62,2%, além de hiperplasia do tecido linfóide associado aos brônquios (BALT) em 36,5%. As 74 amostras histológicas submetidas a técnica de FISH foram classificadas quanto a distribuição de sinalizações em focal (+), multifocal em até 25% do tecido (++), sinalizações entre 25 e 50% do tecido (+++), e sinalizações superiores em 50% do tecido avaliado (++++). Destas, foram observadas sinalizações positivas em 76% dos intestinos, sendo 39,3% com sinalizações +; 33,9% com sinalizações ++; 16% apresentaram sinalizações +++, e 10,7% das amostras apresentaram sinalizações ++++. Já as amostras esplênicas, das 74 amostras, 80% foram positivas pela técnica, destas 30,5% classificadas em +; 37,3% apresentaram sinalizações em ++; 23,7% com sinalizações distribuídas em +++, e 8,5% apresentaram sinalização com distribuição superior a 50% do tecido ++++. A sinalização positiva foi observada em 88% das amostras pulmonares avaliadas, sua classificação em + foi observada em 18,5% das amostras, seguida de 50,8% com classificação em ++. A classificação em +++ foi observada em 18,5% das amostras e ++++ em 12,3%. De acordo com os resultados, a FISH mostrou-se uma técnica possível de ser utilizada para detecção de Chlamydia sp. em cortes histológicos de intestino, baço e pulmão de pombos-comuns (Columba livia). Abstract: The avian chlamydiosis is a bacterial disease of high relevance for avian species as well as for humans, increasing the necessity of establishing fast and effective diagnosis for the detection of the bacteria of the genus Chlamydia, responsible for the diseases. The present study aims to describe the detection of Chlamydia sp. by fluorescence in situ hybridization (FISH) in histological sections of lung, spleen, and intestine from common pigeons (Columba livia), fixed in 10% formalin. Samples from 74 common pigeons were evaluated by FISH and conventional histopathology; the probe used followed a 20-base sequence for annealing, corresponding to the gene encoding the MOMP (Major Outer Membrane Protein) of bacteria of the gender Chlamydia, and added the Alexa Fluor 555® fluorochrome. Histopathology showed predominantly lymphohistiocytic and/or granulocytic enteritis, and lymphohistiocytic serositis/myositis in 28.1% of the intestines. Granulomatous and lymphohistiocytic splenitis, perivasculitis, and multifocal areas of necrosis distributed in 78.4% of the spleen samples evaluated; In lung, lymphohistiocytic and/or granulocytic pneumonia, lymphohistiocytic perivasculitis 62.2%, and bronchus-associated lymphoid tissue hyperplasia (BALT) in 36.5% were observed. The 74 histological samples submitted to the FISH technique were classified according to the distribution of signalizations into focal (+), multifocal in less than 25% tissue (++), signalizations between 25 and 50% of the tissues (+++), and signalizations higher than 50% of the tissues analyzed (++++). Of these, positive signalizations were observed in 76% of the intestines, of which 39.3% showed + signals; 33.9% showed ++ signals; 16% showed +++ signals, and 10.7% of the samples showed ++++ signals. As for the splenic samples, of the 74 samples, 80% were positive by the technique, of these, 30.5% classified as +; 37.3% showed ++ signaling; 23.7% showed signaling distributed in +++, and 8.5% showed signaling with distribution greater than 50% of the tissue ++++. Positive signaling was observed in 88% of lung samples evaluated, its classification in + was observed in 18.5% of samples, followed by 50.8% with classification in ++. The classification in +++ was observed in 18.5% of the samples and ++++ in 12.3%. According to the results, FISH proved to be a possible technique to be used for detection of Chlamydia sp. in histological sections of intestine, spleen, and lung of common pigeons (Columba livia).

Published
2022

28. INFECÇÃO POR MORBILLIVIRUS CANINO EM ONÇA PARDA (Puma concolor) NO ESTADO DE MATO GROSSO, BRASIL – RELATO DE CASO

Author

Lima, Janine Cruvinel de, Morgado, Thais Oliveira, Ribeiro, Karen Ramos, Fontana, Carolina, Cândido, Stéfhano, Dutra, Valeria, Nakazato, Luciano, Catroxo, Márcia, Aguiar, Daniel Moura de, and Borges, Jaqueline Camargo

Abstract

Infecções de felídeos não-domésticos com vírus de carnívoros domésticos são relatadas em todo o mundo. O Morbillivirus canino (CDV) pode determinar diversas alterações clínicas e patológicas em cães domésticos e animais silvestres. Os felídeos selvagens são susceptíveis ao CDV e quando infectados podem desenvolver sinais clínicos neurológicos, respiratórios e gastrointestinais. A pressão da agricultura, indústria e urbanização fragmentou o habitat das onças pardas (Puma concolor) no Brasil tornando-a uma espécie ameaçada de extinção. Mesmo em ambientes adequados, estes felinos enfrentam uma variedade de ameaças, como a caça furtiva da própria espécie e de suas presas. Declínios nas populações de felinos selvagens causadas por doenças infecciosas foram relatados e as taxas de morbidade e mortalidade do CDV verificadas nos felídeos podem ser diversas. Baseando-se na ausência de dados sobre a ocorrência desta virose em onças pardas em Mato Grosso, este trabalho relata infecção natural pelo CDV em duas onças pardas no munícipio de Cuiabá diagnosticado por meio de RT-PCR e microscopia eletrônica. Os animais foram internados e apresentaram sinais clínicos de broncopneumonia aspirativa, que após tratamento estabelecido apresentaram melhora e cura clínica.

Published
2020

29. Structural insights in galectin-1-glycan recognition: Relevance of the glycosidic linkage and the N-acetylation pattern of sugar moieties.

Author

Porciúncula-González, Cecilia, Cagnoni, Alejandro J, Fontana, Carolina, Mariño, Karina V, Saenz Mendez, Patricia, Giacomini, Cecilia, Irazoqui, Gabriela, Porciúncula-González, Cecilia, Cagnoni, Alejandro J, Fontana, Carolina, Mariño, Karina V, Saenz Mendez, Patricia, Giacomini, Cecilia, and Irazoqui, Gabriela

Abstract

Galectins, soluble lectins widely expressed intra- and extracellularly in different cell types, play major roles in deciphering the cellular glycocode. Galectin-1 (Gal-1), a prototype member of this family, presents a carbohydrate recognition domain (CRD) with specific affinity for β-galactosides such as N-acetyllactosamine (β-d-Galp-(1 → 4)-d-GlcpNAc), and mediate numerous physiological and pathological processes. In this work, Gal-1 binding affinity for β-(1 → 6) galactosides, including β-d-Galp-(1 → 6)-β-d-GlcpNAc-(1 → 4)-d-GlcpNAc was evaluated, and their performance was compared to that of β-(1 → 4) and β-(1 → 3) galactosides. To this end, the trisaccharide β-d-Galp-(1 → 6)-β-d-GlcpNAc-(1 → 4)-d-GlcpNAc was enzymatically synthesized, purified and structurally characterized. To evaluate the affinity of Gal-1 for the galactosides, competitive solid phase assays (SPA) and isothermal titration calorimetry (ITC) studies were carried out. The experimental dissociation constants and binding energies obtained were compared to those calculated by molecular docking. These analyses evidenced the critical role of the glycosidic linkage between the terminal galactopyranoside residue and the adjacent monosaccharide, as galactosides bearing β-(1 → 6) glycosidic linkages showed dissociation constants six- and seven-fold higher than those involving β-(1 → 4) and β-(1 → 3) linkages, respectively. Moreover, docking experiments revealed the presence of hydrogen bond interactions between the N-acetyl group of the glucosaminopyranose moiety of the evaluated galactosides and specific amino acid residues of Gal-1, relevant for galectin-glycan affinity. Noticeably, the binding free energies (ΔGbindcalc) derived from the molecular docking were in good agreement with experimental values determined by ITC measurements (ΔGbindexp), evidencing a good correlation between theoretical and experimental approaches, which validates the in silico simulations and constitutes an important tool for t

Published
2021
Full Text
View/download PDF

30. Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

Author

Rodríguez-Baño, Jesús, primary, Pachón, Jerónimo, additional, Carratalà, Jordi, additional, Ryan, Pablo, additional, Jarrín, Inmaculada, additional, Yllescas, María, additional, Arribas, José Ramón, additional, Berenguer, Juan, additional, Aznar Muñoz, Esther, additional, Gil Divasson, Pedro, additional, González Muñiz, Patricia, additional, Muñoz Aguirre, Clara, additional, Díaz Menéndez, Marta, additional, de la Calle Prieto, Fernando, additional, Arsuaga Vicente, Marta, additional, Trigo Esteban, Elena, additional, Pérez Valero, Ignacio, additional, de Miguel Buckley, Rosa, additional, Cadiñaños Loidi, Julen, additional, Diaz Pollan, Beatriz, additional, Martín Carbonero, Luz, additional, Ramos Ramos, Juan Carlos, additional, Loeches Yagüe, Belén, additional, Montejano Sánchez, Rocío, additional, González García, Juan, additional, García Rodríguez, Julio, additional, Ramírez, Margarita, additional, Gutiérrez, Isabel, additional, Tejerina, Francisco, additional, Aldámiz-Echevarría, Teresa, additional, Díez, Cristina, additional, Fanciulli, Chiara, additional, Pérez-Latorre, Leire, additional, Pinilla, Blanca, additional, López, Juan Carlos, additional, Such Diaz, Ana, additional, Álvaro Alonso, Elena, additional, Torres Macho, Juan, additional, Cuevas Tascon, Guillermo, additional, Jiménez González de Buitrago, Eva, additional, Brañas Baztán, Fátima, additional, Valencia de la Rosa, Jorge, additional, Pérez Butragueño, Mario, additional, Fernández Jiménez, Inés, additional, Muñiz Nicolás, Gemma, additional, Sepúlveda Berrocal, Antonia, additional, Gato Díez, Alberto, additional, Toledano Sierra, María Pilar, additional, García Butenegro, María Paz, additional, Peláez Ballesta, Ana Isabel, additional, Morcillo Rodríguez, Elena, additional, Fernández Romero, Isidoro, additional, Peláez Ballesta, Cristina, additional, Guirado Torrecillas, María Isabel, additional, Goikoetxea Agirre, Josune, additional, Bereciartua Bastarrica, Elena, additional, Guio Carrión, Laura, additional, Rodríguez Álvarez, Regino, additional, Ibarrola Hierro, Marta, additional, Pérez Hernández, Isabel A., additional, Pérez Zapata, Inés, additional, Román Soto, Sergio, additional, Kallouchi, Mohamed, additional, Domínguez Vicent, Juan Ramón, additional, Silvariño Fernández, Rafae, additional, Ugalde Espiñeira, Jon, additional, Sanjuan López, Ainhoa, additional, García Martínez, Silvia, additional, Temprano Gogenola, Mikel, additional, Asensi, Víctor, additional, Suárez, Silvia, additional, Suárez, Lucia, additional, Yllera, Carmen, additional, Rivas-Carmenado, María, additional, Romero-Palacios, Alberto, additional, Ruiz Aragón, Jesús, additional, Jiménez Aguilar, Patricia, additional, Fernández Ávila, Ma Luisa, additional, Castilla Ortiz, Rosario, additional, Alende Castro, Vanesa, additional, Pérez García, Cristina, additional, Fernández Morales, Marta, additional, Valle Feijoo Begoña Rodríguez Ferreira, María Lorena María, additional, Gómez-Junyent, Joan, additional, Villar-García, Judit, additional, López-Montesinos, Inmaculada, additional, Arrieta-Aldea, Itziar, additional, Rial-Villavecchia, Abora, additional, García Vázquez, Elisa, additional, Roura Piloto, Aychel Elena, additional, Moral Escudero, Encarnación, additional, Hernández Torres, Alicia, additional, Albendín Iglesias, Helena, additional, Vinuesa García, David, additional, Martínez Montes, Clara, additional, De la Hera Fernández, Francisco Javier, additional, Anguita Santos, Francisco, additional, Ruiz Sancho, Andrés, additional, Díaz de Brito Fernández, Vicens, additional, Sanmarti Vilamala, Montserrat, additional, España Cueto, Sergio, additional, Molina Morant, Daniel, additional, González-Cuevas, Araceli, additional, Chara Cervantes, Joel Elías, additional, Policarpo Torres, Guillem, additional, Ortega Montoliu, Meritxell, additional, Angerri Nadal, Mònica, additional, De Genover Gil, Ariadna, additional, Patera, Eleni, additional, Godoy Lorenzo, Rita, additional, Zioga, Evangelia Anna María, additional, Isern Fernández, Virginia, additional, Sabbagh Fajardo, Carlos Enrique, additional, Ferrer Ribera, Ana, additional, Bea Serrano, Carlos, additional, Oltra Sempere, Rosa, additional, Vela Bernal, Sara, additional, Albiol Viñals, Paloma, additional, Pedromingo Kus, Miguel, additional, Garcinuño, María Ángeles, additional, Fiorante, Silvana, additional, Pérez Pinto, Sergio, additional, de la Vega, Alexandra, additional, Fariñas Álvarez, María Carmen, additional, González Rico, Claudia, additional, Arnaiz de las Revillas, Francisco, additional, Giménez, Teresa, additional, Calvo, Jorge, additional, Meije Castillo, Yolanda, additional, Duarte Borges, Alejandra, additional, Pareja Coca, Júlia, additional, Clemente Presas, Mercedes, additional, Sanz Salvador, Xavier, additional, Pérez Rodríguez, Ma Teresa, additional, Sousa, Adrián, additional, Pérez González, Alexandre, additional, Longueira, Rebeca, additional, Araujo, Alejandro, additional, Alonso Martínez, Blanca, additional, García Escudero, Laura, additional, Lidia Kamel Rey, Sara, additional, Roa Alonso, David, additional, Avilés Parra, Juan Pablo, additional, Pelegrín Senent, Iván, additional, Rouco Esteves Marques, Rosana, additional, Raich Montiu, Laia, additional, Souto Higueras, Jessica, additional, Gálvez Bobadilla, Manuel Alejandro, additional, Parra Ruiz, Jorge, additional, Ramos Sesma, Violeta, additional, Velasco Fuentes, Sara, additional, García Pereña, Laura, additional, Lluna Carrascosa, Alfonso, additional, Gilaberte Reyzábal, Sergio, additional, Liébana Gómez, Mónica, additional, Salillas Hernando, Juan, additional, Serrano Martínez, Alberto, additional, Torralba González de Suso, Miguel, additional, Martínez Martín, Patricia, additional, Rábago Lorite, Isabel, additional, González-Ruano Pérez, Patricia, additional, Pérez-Monte Mínguez, Beatriz, additional, García Flores, Ángeles, additional, Comas Casanova, Pere, additional, Martín Plata, Andrea, additional, Santana Báez, Sergio Manuel, additional, Sanz Peláez, Oscar, additional, Mohamed Ramírez, Karim, additional, Robaina Bordón, José María, additional, Vílchez Rueda, Helem Haydeé, additional, Riera Jaume, Melchor, additional, Mut Ramon, Gemma, additional, Gavalda Manso, Meritxell, additional, Planas Bibiloni, Lluis, additional, Castelo Corral, Laura, additional, Ramos Merino, Lucía, additional, Sánchez Vidal, Efrén, additional, Rodríguez Mayo, María, additional, Míguez Rey, Enrique, additional, García de Lomas Guerrero, José M., additional, De la Torre Lima, Javier, additional, Correa Ruiz, Ana, additional, Fernández Sánchez, Fernando, additional, Jiménez-García, Nicolás, additional, Sierra-Monzón, José Luis, additional, Gracia-Tello, Borja, additional, Hernández-Bonaga, María, additional, Pellejero, Galadriel, additional, Asín-Corrochano, Marta, additional, Boix Palop, Lucia, additional, Calbo, Esther, additional, Badía, Cristina, additional, Dietl, Beatriz, additional, Lucía, Gómez, additional, Domínguez-Castellano, Ángel, additional, Ríos-Villegas, María José, additional, del Toro, María D., additional, Palacios Baena, Zaira R., additional, Salamanca-Rivera, Elena, additional, Marín, Elena, additional, Almadana, Virginia, additional, Pérez-Galera, Salvador, additional, González-Iglesias, Luisa, additional, Abelenda-Alonso, Gabriela, additional, Álvarez-Pouso, Claudia, additional, Escrihuela, Francesc, additional, Gudiol, Carlota, additional, Lorenzo-Esteller, Laia, additional, Niubó, Jordi, additional, Podzamczer, Daniel, additional, Pujol, Miquel, additional, Rombauts, Alexander, additional, Salvert Lletí, Miguel, additional, Gil Sánchez, Ricardo, additional, Jiménez Escrig, Marta, additional, Parra Gómez, Laura, additional, Tasias Pitarch, Mariona, additional, Navarro Vilasaró, Marta, additional, Machado Sicilia, María Luisa, additional, Gomila Grange, Aina, additional, Calzado Isbert, Sonia, additional, Carrasco Antón, Nerea, additional, Petkova-Saiz, Elizabet, additional, Cabello Úbeda, Alfonso, additional, Górgolas Hernández-Mora, Miguel, additional, Sánchez-Pernaute, Olga, additional, Dueñas Gutiérrez, Carlos, additional, Martin Guerra, Javier, additional, Castrodeza Sanz, José Javier, additional, Fernández Espinilla, Virginia, additional, Rodríguez Fernández, Laura, additional, González-Moreno, Juan, additional, Villoslada Gelabert, Aroa, additional, Ribot Sanso, María Antonia, additional, Fernández-Baca, María Victoria, additional, Hernández Milian, Almudena, additional, Morán Rodríguez, Miguel Ángel, additional, Ortiz de Zárate Ibarra, Zuriñe, additional, Portu Zapirain, José Joaquin, additional, Saez de Adana Arroniz, Ester, additional, Gainzarain Arana, Juan Carlos, additional, Meca Birlanga, Olga, additional, del Amor Espín, Ma Jesús, additional, Viqueira González, Montserrat, additional, García García, Josefina, additional, Martínez Madrid, Onofre, additional, Bernal Morell, Enrique, additional, Alcaraz, Antonia, additional, Muñoz, Ángeles, additional, Pina, Ignacio, additional, de la Rosa, Vicente, additional, Caínzos Romero, Tamara, additional, Sánchez Trigo, Sabela, additional, Mariño Callejo, Ana Isabel, additional, Álvarez Díaz, Hortensia, additional, Valcarce Pardeiro, Nieves, additional, Sánchez Serrano, Adriana, additional, Piñar Cabezos, Diana, additional, García Villalba, Eva Pilar, additional, Aguayo Jiménez, Carmen, additional, Ruíz Campuzano, María, additional, Naranjo Velasco, Virginia, additional, Santos Peña, Marta, additional, Mora Delgado, Juan, additional, Sevilla Moreno, Israel, additional, Lojo Cruz, Cristina, additional, Kortajarena Urkola, Xabier, additional, Iribarren Loyarte, José Antonio, additional, Bustinduy Odriozola, María Jesús, additional, Ibarguren Pinilla, Maialen, additional, Álvarez Rodríguez, Ignacio, additional, Martínez Marcos, Francisco Javier, additional, Rodríguez Gómez, Francisco Javier, additional, Asschert Agüero, Isabel, additional, Muñoz Beamud, Francisco, additional, Ruiz Reina, Antonio José, additional, Llenas-García, Jara, additional, González-Cuello, Inmaculada, additional, Hellín-Valiente, Elena, additional, Martínez Birlanga, Esther, additional, Tafalla Torres, José Manuel, additional, Calderón Parra, Jorge, additional, Escudero López, Gabriela, additional, Gutiérrez Martín, Isabel, additional, Andrés Eisenhofer, Ane, additional, García Prieto, Sonia, additional, Álvarez Franco, Raquel, additional, Roger Zapata, Daniel, additional, Martínez Cifre, Blanca, additional, Aranda Rife, Elena, additional, Martín Rubio, Irene, additional, Barbosa Ventura, André, additional, Garrido, Javier, additional, Gonzalo, Concepción, additional, Piñero, Iván, additional, de la Cruz Felipe, Nieves, additional, Talavera García, Eva, additional, Lamata Subero, Marta, additional, Mendoza Roy, Paula, additional, García de Carlos, María Soledad, additional, Lajusticia Aisa, Justo, additional, Arteche Eguizabal, Lorea, additional, Urrutia Losada, Ainhoa, additional, Domingo Echaburu, Saioa, additional, Cuadros Tito, Pedro Ángel, additional, Orbe Narváez, Gurutz, additional, Liébana Martos, Ma del Carmen, additional, Roldán Fontana, Carolina, additional, Herrero Rodríguez, Carmen, additional, Duro Ruiz, Gaspar, additional, Pérez Parra, Santiago, additional, Mera Fidalgo, Arantzazu, additional, Hortos Alsina, Miquel, additional, Alberich Conesa, Ana, additional, Bladé Vidal, Lourdes, additional, Merchante Gutiérrez, Nicolás, additional, León Jiménez, Eva, additional, Espíndola Gómez, Reinaldo, additional, Erostarbe Gallardo, María, additional, Martínez Pérez-Crespo, Pedro, additional, Cisneros, José Miguel, additional, Aguilar-Guisado, Manuela, additional, Aldabó, Teresa, additional, Bueno, Claudio, additional, Cordero-Matía, Elisa, additional, Escoresca, Ana, additional, Infante, Carmen, additional, Guillermo, Martín, additional, Salto, Sonsoles, additional, Gioia, Francesca, additional, Vizcarra, Pilar, additional, Fortún Abete, Jesús, additional, Martín Dávila, Pilar, additional, Moreno Guillén, Santiago, additional, Oteo Revuelta, José A., additional, García-García, Concepción, additional, Santibañez Sáenz, Paula, additional, Cervera Acedo, Cristina, additional, Azcona Gutiérrez, José M., additional, Reguera Iglesias, José María, additional, Plata Ciezar, Antonio, additional, Valiente de Santis, Lucia, additional, Sobrino Diaz, Beatriz, additional, and Ruiz Mesa, Juan Diego, additional

Published
2021
Full Text
View/download PDF

39. ADENITE SEBÁCEA EM UM CANINO: RELATO DE CASO

Author

Pase Montagnini, Karim Cristhine, primary, Das Chagas Goulart, Juliana, additional, Colombari Cheng, Arthur, additional, Smaha De Jesus Lima, Joana Cristina, additional, Fontana, Carolina, additional, Donat Almagro, Larissa, additional, Dutra da Silveira, Solimar, additional, and De Marco Viott, Aline, additional

Published
2020
Full Text
View/download PDF

40. LINFOMA ESPONTÂNEO EM CAMUNDONGO Mus musculus – RELATO DE CASO

Author

Fontana, Carolina, primary, Colombari Cheng, Arthur, additional, Das Chagas Goulart, Juliana, additional, Pase Montagnin, Karim Cristhine, additional, Smaha de Jesus Lima, Joana Cristina, additional, Fucks de Souza, Carolina, additional, Piccoli, Ronaldo José, additional, and De Marco Viott, Aline, additional

Published
2020
Full Text
View/download PDF

41. MIXOMA CUTÂNEO: RELATO DE CASO

Author

Pase Montagnini, Karim Cristhine, primary, Das Chagas Goulart, Juliana, additional, Colombari Cheng, Arthur, additional, Smaha de Jesus Lima, Joana Cristina, additional, Fontana, Carolina, additional, Gruchouskei, Leonardo, additional, Dahm, Vinicius, additional, and De Marco Viott, Aline, additional

Published
2020
Full Text
View/download PDF

43. Characteristics and predictors of death among 4035 consecutively hospitalized patients with COVID-19 in Spain

Author

Berenguer, Juan, primary, Ryan, Pablo, additional, Rodríguez-Baño, Jesús, additional, Jarrín, Inmaculada, additional, Carratalà, Jordi, additional, Pachón, Jerónimo, additional, Yllescas, María, additional, Arriba, José Ramón, additional, Aznar Muñoz, Esther, additional, Gil Divasson, Pedro, additional, González Muñiz, Patricia, additional, Muñoz Aguirre, Clara, additional, López, Juan Carlos, additional, Ramírez-Schacke, Margarita, additional, Gutiérrez, Isabel, additional, Tejerina, Francisco, additional, Aldámiz-Echevarría, Teresa, additional, Díez, Cristina, additional, Fanciulli, Chiara, additional, Pérez-Latorre, Leire, additional, Parras, Francisco, additional, Catalán, Pilar, additional, García-Leoni, María E., additional, Pérez-Tamayo, Isabel, additional, Puente, Luis, additional, Cedeño, Jamil, additional, Berenguer, Juan, additional, Díaz Menéndez, Marta, additional, de la Calle Prieto, Fernando, additional, Arsuaga Vicente, Marta, additional, Trigo Esteban, Elena, additional, Lago Núñez, Mª del Mar, additional, de Miguel Buckley, Rosa, additional, Cadiñaños Loidi, Julen, additional, Busca Arenzana, Carmen, additional, Mican, Alfredo, additional, Mora Rillo, Marta, additional, Ramos Ramos, Juan Carlos, additional, Loeches Yagüe, Belén, additional, Bernardino de la Serna, José Ignacio, additional, García Rodríguez, Julio, additional, Arribas López, José Ramón, additional, Such Diaz, Ana, additional, Álvaro Alonso, Elena, additional, Izquierdo García, Elsa, additional, Torres Macho, Juan, additional, Cuevas Tascon, Guillermo, additional, Troya García, Jesús, additional, Mestre Gómez, Beatriz, additional, Jiménez González de Buitrago, Eva, additional, Fernández Jiménez, Inés, additional, Tebar Martínez, Ana Josefa, additional, Brañas Baztán, Fátima, additional, Valencia de la Rosa, Jorge, additional, Pérez Butragueño, Mario, additional, Alvarado Blasco, Marta, additional, Sepúlveda Berrocal, Mª Antonia, additional, Yera Bergua, Carmen, additional, Toledano Sierra, Pilar, additional, Cano Llorente, Verónica, additional, Zafar Iqubal-Mirza, Sadaf, additional, Muñiz, Gema, additional, Martín Pérez, Inmaculada, additional, Mozas Moriñigo, Helena, additional, Alguacil, Ana, additional, García Butenegro, María Paz, additional, Peláez Ballesta, Ana Isabel, additional, Morcillo Rodríguez, Elena, additional, Goikoetxea Agirre, Josune, additional, Blanco Vidal, María José, additional, Nieto Arana, Javier, additional, del Álamo Martínez de Lagos, Mikel, additional, Pérez Hernández, Isabel A., additional, Pérez Zapata, Inés, additional, Silvariño Fernández, Rafael, additional, Ugalde Espiñeira, Jon, additional, Asensi Álvarez, Víctor, additional, Suárez Pérez, Lucia, additional, Suárez Diaz, Silvia, additional, Yllera Gutiérrez, Carmen, additional, Boix, Vicente, additional, Díez Martínez, Marcos, additional, Carreres Candela, Melissa, additional, Gómez-Ayerbe, Cristina, additional, Sánchez-Lora, Javier, additional, Velasco Garrido, José Luis, additional, López-Jódar, María, additional, Santos González, Jesús, additional, Ruiz Aragón, Jesús, additional, Virto Peña, Ianire, additional, Alende Castro, Vanessa, additional, Brea Aparicio, Ruth, additional, Vega Molpeceres, Sonia, additional, Pons Viñas, Estel, additional, del Río Pérez, Oscar, additional, Valero Rovira, Silvia, additional, Villar-García, Judit, additional, Gómez-Junyent, Joan, additional, Knobel, Hernando, additional, Cánepa, María Cecilia, additional, Castañeda Espinosa, Silvia, additional, Sorli Redò, Luisa, additional, Güerri-Fernández, Roberto, additional, Milagro Montero, María, additional, Horcajada, Juan Pablo, additional, García Vázquez, Elisa, additional, Moral Escudero, Encarnación, additional, Hernández Torres, Alicia, additional, García Almodóvar, Esther, additional, Sáez Barberá, Carmen, additional, Karroud, Zineb, additional, Hernández Quero, José, additional, Vinuesa García, David, additional, García Fogeda, José Luis, additional, Peregrina, José Antonio, additional, Novella Mena, María, additional, Hernández Gutiérrez, Cristina, additional, Sanz Moreno, José, additional, Pérez Tanoira, Ramón, additional, Sierra Rodríguez, Rodrigo, additional, Alonso Menchén, David, additional, Gutiérrez García, Aida, additional, Arranz Caso, Alberto, additional, Cuadros González, Juan, additional, Álvarez de Mon Soto, Melchor, additional, Díaz de Brito Fernández, Vicente Ferrer, additional, Sanmarti Vilamala, Montserrat, additional, Gabarrell Pascuet, Aina, additional, Molina Morant, Daniel, additional, España Cueto, Sergio, additional, Cámara Fernández, Jonathan, additional, Sabater Gil, Albert, additional, Muñoz López, Laura, additional, Sáez Escolano, Paula, additional, Bejarano Tello, Esperanza, additional, Sempere Alcocer, Marco Antonio, additional, Álvarez Martin, Salvador, additional, De los Santos Gil, Ignacio, additional, García-Fraile, Lucio, additional, Sampedro Núñez, Miguel, additional, Barrios Blandino, Ana, additional, Rodríguez Franco, Carlos, additional, Useros Brañas, Daniel, additional, Villa Martí, Almudena, additional, Oliver Ortega, Javier, additional, Costanza Espiño Álvarez, Alexia, additional, Sanz Sanz, Jesús, additional, Rexach Fumaña, María, additional, Abascal Cambras, Ivette, additional, Pérez Jaén, Ana del Cielo, additional, Sala Jofre, Clara, additional, Casas Rodríguez, Susana, additional, Tortajada Alamilla, Cecilia, additional, Oltra, Carmina, additional, Masiá Canuto, Mar, additional, Gutiérrez Rodero, Félix, additional, Ferrer Ribera, Ana, additional, Bea Serrano, Carlos, additional, Pedromingo Kus, Miguel, additional, Garcinuño, María Ángeles, additional, Fiorante, Silvana, additional, Pérez Pinto, Sergio, additional, Hernández Machín, Pilar, additional, Alastrué Violeta, Alba, additional, Fariñas Álvarez, María Carmen, additional, González Rico, Claudia, additional, Arnaiz de las Revillas, Francisco, additional, Calvo, Jorge, additional, Gozalo, Mónica, additional, Mora Gómez, Francisco, additional, Milagro Beamonte, Ana, additional, Latorre-Millán, Miriam, additional, Rezusta López, Antonio, additional, Martínez Sapiña, Ana, additional, Meije, Yolanda, additional, Duarte Borges, Alejandra, additional, Pareja Coca, Julia, additional, Clemente Presas, Mercedes, additional, Losa García, Juan Emilio, additional, Vegas Serrano, Ana, additional, Pérez-Rodríguez, M. Teresa, additional, Pérez González, Alexandre, additional, Belhassen-García, Moncef, additional, Rodríguez-Alonso, Beatriz, additional, López-Bernus, Amparo, additional, Carbonell, Cristina, additional, Torres Perea, Rafael, additional, Cantón de Seoane, Juan, additional, Alonso, Blanca, additional, Kamal, Sara Lidia, additional, Cajuela, Lucia, additional, Roa, David, additional, Cervero, Miguel, additional, Oreja, Alberto, additional, Avilés, Juan Pablo, additional, Martín, Lidia, additional, Pelegrín Senent, Iván, additional, Rouco Esteves Marques, Rosana, additional, Parra Ruiz, Jorge, additional, Ramos Sesma, Violeta, additional, Abadia Otero, Jessica, additional, Salillas Hernando, Juan, additional, Torres Sánchez del Arco, Robert, additional, Torralba González de Suso, Miguel, additional, Serrano Martínez, Alberto, additional, Gilaberte Reyzábal, Sergio, additional, Pacheco Martínez-Atienza, Marina, additional, Liébana Gómez, Mónica, additional, Fernández Rodríguez, Sara, additional, Varela Plaza, Álvaro, additional, Calvo Sánchez, Henar, additional, Martínez Martín, Patricia, additional, González- Ruano, Patricia, additional, Malmierca Corral, Eduardo, additional, Rábago Lorite, Isabel, additional, Pérez-Monte Mínguez, Beatriz, additional, García Flores, Ángeles, additional, Comas Casanova, Pere, additional, Sirisi, Merce, additional, Rojas, Richard, additional, Díaz de Tuesta del Arco, José Luis, additional, Figueroa Cerón, Ruth, additional, González Sarria, Ander, additional, Alemán Valls, Remedios, additional, Alonso Socas, María del Mar, additional, Sanz Peláez, Oscar, additional, Mohamed Ramírez, Karim, additional, Riera Jaume, Melchor, additional, Vilchez, Helem Haydee, additional, Albertí, Francesc, additional, Cañabate, Ana Isabel, additional, Moreno Cuerda, Víctor J., additional, Álvarez Kaelis, Silvia, additional, Álvarez Zapatero, Beatriz, additional, García García, Alejandro, additional, Isaba Ares, Elena, additional, Morcate Fernández, Covadonga, additional, Pérez Rodríguez, Andrea, additional, Ramos Merino, Lucía, additional, Castelo Corral, Laura, additional, Rodríguez Mahía, María, additional, González Bardanca, Mónica, additional, Sánchez Vidal, Efrén, additional, Míguez Rey, Enrique, additional, De la Torre Lima, Javier, additional, García de Lomas Guerrero, José Mª, additional, Morte, Elena, additional, Loscos, Silvia, additional, Camón, Ana, additional, Gómez García, Lucía, additional, Boix Palop, Lucia, additional, Dietl Gómez-Luengo, Beatriz, additional, Pedrola Gorrea, Iris, additional, Blasco Claramunt, Amparo, additional, López Mestanza, Cristina, additional, Fraile Villarejo, Esther, additional, Tosco Núñez, Tomás, additional, Aroca Ferri, María, additional, Algado Rabasa, José Tomas, additional, Garijo Saiz, Ana María, additional, Amador Prous, Concepción, additional, Baño, Jesús Rodriguez, additional, Retamar, Pilar, additional, Valiente, Adoración, additional, López-Cortés, Luis E., additional, Sojo, Jesús, additional, Gutiérrez-Gutiérrez, Belén, additional, Bravo-Ferrer, José, additional, Salamanca, Elena, additional, Palacios, Zaira R., additional, Pérez-Palacios, Patricia, additional, Peral, Enrique, additional, Pérez de León, José Antonio, additional, Sánchez-Gómez, Jesús, additional, Marín-Barrera, Lucía, additional, García-Jiménez, Domingo, additional, Abelenda-Alonso, Gabriela, additional, Ardanuy, Carmen, additional, Bergas, Alba, additional, Cuervo, Guillermo, additional, Domínguez, María Ángeles, additional, Fernández-Huerta, Miguel, additional, Gudiol, Carlota, additional, Lorenzo-Esteller, Laia, additional, Niubó, Jordi, additional, Pérez-Recio, Sandra, additional, Podzamczer, Daniel, additional, Pujol, Miquel, additional, Rombauts, Alexander, additional, Trullen, Núria, additional, Salavert Lletí, Miguel, additional, Castro Hernández, Iván, additional, Hernández Belmonte, Adriana, additional, Martínez Goñi, Raquel, additional, Navarro Vilasaró, Marta, additional, Calzado Isbert, Sonia, additional, Cervantes García, Manuel, additional, Gomila Grange, Aina, additional, Gasch Blasi, Oriol, additional, Machado Sicilia, María Luisa, additional, Van den Eynde Otero, Eva, additional, Falgueras López, Luis, additional, Navarro Sáez, María del Carmen, additional, Martínez, Esteban, additional, Marcos, Mª Ángeles, additional, Mosquera, Mar, additional, Blanco, José Luis, additional, Laguno, Montserrat, additional, Rojas, Jhon, additional, González-Cordón, Ana, additional, Inciarte, Alexy, additional, Torres, Berta, additional, De la Mora, Lorena, additional, Soriano, Alex, additional, Martínez Macias, Olalla, additional, Pérez Doñate, Virginia, additional, Cabello Úbeda, Alfonso, additional, Carrasco Antón, Nerea, additional, Álvarez Álvarez, Beatriz, additional, Petkova Saiz, Elizabet, additional, Górgolas Hernández-Mora, Miguel, additional, Prieto Pérez, Laura, additional, Carrillo Acosta, Irene, additional, Heili Frades, Sara, additional, Villar Álvarez, Felipe, additional, Fernández Roblas, Ricardo, additional, Milicua Muñoz, José María, additional, Fernández Espinilla, Virginia, additional, Dueñas Gutiérrez, Carlos Jesús, additional, Hernán García, Cristina, additional, González-Romo, Fernando, additional, Merino Amador, Paloma, additional, Rueda López, Alba, additional, Martínez Jordán, Jorge, additional, Medrano Pardo, Sara, additional, Díaz de la Torre, Irene, additional, Posada Franco, Yolanda, additional, Delgado-Iribarren, Alberto, additional, López-Contreras González, Joaquín, additional, Pascual Alonso, Pablo, additional, Pomar Solchaga, Virginia, additional, Rabella García, Nuria, additional, Benito Hernández, Natividad, additional, Domingo Pedrol, Pere, additional, Bonfill Cosp, Xavier, additional, Padrós Selma, Rafael, additional, Puig Campmany, Mireia, additional, Mancebo Cortés, Jordi, additional, Gurguí Ferrer, Mercè, additional, Íñigo Pestaña, Melania, additional, Pérez García, Alejandra, additional, Sorní Moreno, Patricia, additional, Izko Gartzia, Nora, additional, Membrillo de Novales, Francisco Javier, additional, Simón Sacristán, María, additional, Zamora Cintas, Maribel, additional, Martínez Martínez, Yolanda, additional, Fernández-González, Pablo, additional, Alcántara Nicolás, Francisco, additional, Aguirre Vila-Cora, Alejandro, additional, López Tizón, Elena, additional, Ramírez-Olivencia, Germán, additional, Estébanez Muñoz, Miriam, additional, Sáez de Adana Arróniz, Ester, additional, Portu Zapirain, Joseba, additional, Gainzarain Arana, Juan Carlos, additional, Ortiz de Zárate Ibarra, Zuriñe, additional, Moran Rodríguez, Miguel Ángel, additional, Canut Blasco, Andrés, additional, Hernáez Crespo, Silvia, additional, Balerdi Sarasola, Leire, additional, Morales García, Cristina, additional, Corral Saracho, Miguel, additional, Valcarce González, Zeltia, additional, Arenal Andrés, Noelia, additional, Rodríguez Tarazona, Raquel Elisa, additional, Iglesias Llorente, Laura, additional, Loureiro Rodríguez, Beatriz, additional, Sánchez Montalvá, Adrián, additional, Espinosa Pereiro, Juan, additional, Almirante, Benito, additional, Miarons, Marta, additional, Sellarés, Júlia, additional, Larrosa, María, additional, García, Sonia, additional, Marzo, Blanca, additional, Villamarín, Miguel, additional, Fernández, Nuria, additional, Pérez-Jorge Peremarch, Conchita, additional, Resino Foz, Elena, additional, Espigares Correa, Andrea, additional, Álvarez de Espejo Montiel, Teresa, additional, Navas Clemente, Iván, additional, Quijano Contreras, María Isabel, additional, Nieto Fernández del Campo, Luis Alberto, additional, Jiménez Álvarez, Guillermo, additional, Guillamón Sánchez, Mercedes, additional, García García, Josefina, additional, Muñoz Hornero, Constanza, additional, Mariño Callejo, Ana, additional, Valcarce Pardeiro, Nieves, additional, Smithson Amat, Alex, additional, Chico Chumillas, Cristina, additional, Sánchez Serrano, Adriana, additional, García Villalba, Eva Pilar, additional, Jiménez Martínez, Isabel, additional, Estrada Fernández, Guillermo, additional, Lorén Vargas, María, additional, Parra Arribas, Nuria, additional, Martínez Cilleros, Carmen, additional, Villasante de la Puente, Aránzazu, additional, García Delange, Teresa, additional, Ruiz Rodríguez, María José, additional, Robledo del Prado, Marta, additional, Abad Almendro, Juan Carlos, additional, Muñoz del Rey, José Román, additional, Jiménez Álvaro, Montaña, additional, Coy Coy, Javier, additional, Poquet Catala, Inmaculada, additional, Santos Peña, Marta, additional, Naranjo Velasco, Virginia, additional, Manso Gómez, Tamara, additional, Quilez Ágreda, Delia, additional, Barbeito Castiñeiras, Gema, additional, Domínguez Santalla, María Jesús, additional, Mao Martín, Laura, additional, Alonso Navarro, Rodrigo, additional, Ampuero Martinich, Jose David, additional, Barrós González, Raquel, additional, Galindo Martín, María Aránzazu, additional, Herrera Pacheco, Lourdes, additional, Martínez Avilés, Rocío, additional, Rodrigo González, Sara, additional, Rodríguez Leal, Cristóbal Manuel, additional, Romay Lema, Eva María, additional, Suárez Gil, Roi, additional, Ibarguren Pinilla, Maialen, additional, Marimón Ortiz de Zárate, José María, additional, Vidaur Tello, Loreto, additional, Kortajarena Urkola, Xabier, additional, García Gómez, Miriam, additional, Aranguren Arostegui, Asier, additional, Álvarez de Castro, Maria, additional, Martínez Mateu, Cintia María, additional, Rodríguez Gómez, Francisco, additional, Muñoz Beamud, Francisco, additional, Chamarro Martí, Elena, additional, Cardona Rivera, Merce, additional, Zakariya-Yousef Breval, Ismail, additional, Rico Rodríguez, Marta, additional, Llenas García, Jara, additional, Sánchez Arenas, Mª Carmen, additional, Fernández Cruz, Ana, additional, Calderón Parra, Jorge, additional, López Dosil, Marcos, additional, Ramos Martínez, Antonio, additional, Múñez Rubio, Elena, additional, Callejas Díaz, Alejandro, additional, Vázquez Comendador, José Manuel, additional, Diego Yagüe, Itziar, additional, Expósito Palomo, Esther, additional, Anel Pedroche, Jorge, additional, Álvarez Franco, Raquel, additional, Fernández de Orueta, Lucía, additional, Vates Gómez, Roberto, additional, Cardona Arias, Andrés Felipe, additional, Marguenda Contreras, Pablo, additional, Gaspar Alonso-Vega, Gabriel, additional, Aranda Rife, Elena María, additional, Martínez Cifre, Blanca, additional, Roger Zapata, Daniel, additional, Martín Rubio, Irene, additional, Barbosa Ventura, André, additional, Piñero, Iván, additional, Bahamonde Carrasco, Alberto, additional, Runza Buznego, Paula, additional, Talavera García, Eva, additional, Lamata Subero, Marta, additional, Urrutia Losada, Ainhoa, additional, Arteche Eguizabal, Lorea, additional, Delgado Sánchez, Elisabet, additional, Molina Peinado, Virginia, additional, Caro Bragado, Sarah, additional, Domínguez de Pablos, Gema, additional, Roldán Fontana, Carolina, additional, Herrero Rodríguez, Carmen, additional, Force Sanmartín, Luis, additional, Aranega, Raquel, additional, Mera Fidalgo, Arantzazu, additional, Toda Savall, María Roca, additional, Merchante Gutiérrez, Nicolas, additional, León Jiménez, Eva María, additional, Del Pozo, José Luís, additional, Serralta Buades, Josefa, additional, Cabrera Tejada, Ginger Giorgiana, additional, Fernández-Ruiz, Mario, additional, Aguado, José María, additional, Maestro de la Calle, Guillermo, additional, Cisneros, José Miguel, additional, Aguilar-Guisado, Manuela, additional, Aldabó, Teresa, additional, Avilés, María Dolores, additional, Bueno, Claudio, additional, Cordero-Matía, Elisa, additional, Escoresca, Ana, additional, Gálvez-Benítez, Lydia, additional, Infante, Carmen, additional, Martín, Guillermo, additional, Praena, Julia, additional, Roca, Cristina, additional, Salamanca, Celia, additional, Suárez-Benjumea, Alejandro, additional, Vizcarra, Pilar, additional, Quereda, Carmen, additional, Rodriguez Dominguez, Mario José, additional, Gioia, Francesca, additional, Norman, Francesca, additional, Del Campo, Santos, additional, Cantón Moreno, Rafael, additional, Oteo Revuelta José, Antonio, additional, Santibáñez Sáenz, Paula, additional, Cervera Acedo, Cristina, additional, Ruiz Martínez, Carlos, additional, Blanco Ramos, José R., additional, Azcona Gutiérrez, José M., additional, García García, Concepción, additional, Alba Fernández, Jorge, additional, Ibarra Cucalón, Valvanera, additional, San Franco, Mercedes, additional, Metola Sacristán, Luis, additional, Meijide Míguez, Héctor, additional, Paulos Viñas, Silvia, additional, Menéndez, Justo, additional, Villares Fernández, Paula, additional, Montes Andújar, Lara, additional, Navarro Batet, Álvaro, additional, Ferrer Santolaria, Anna, additional, Padilla Salazar, María de la Luz, additional, Abella Vázquez, Lucy, additional, Hayek Peraza, Marcelino, additional, García Pardo, Antonio, additional, Hernández Carballo, Carolina, additional, Ruiz Fernández, Andrés Javier, additional, Barrio López, Isabel, additional, Martakoush, Alí, additional, Rojas-Vieyra, Agustín, additional, García Calvo, Sonia, additional, Villarreal García-Lomas, Mercedes, additional, Vizcaíno Callejón, Marta, additional, García García, María Pilar, additional, Lérida Urteaga, Ana, additional, Carrasco Fons, Natalia, additional, María Sanjuan, Beatriz, additional, Martín González, Lydia, additional, Sanz Zamudio, Camilo, additional, Alejos, Belén, additional, Moreno, Cristina, additional, Rava, Marta, additional, Iniesta, Carlos, additional, Izquierdo, Rebeca, additional, Suárez-García, Inés, additional, Díaz, Asunción, additional, Ruiz-Alguero, Marta, additional, and Hernando, Victoria, additional

Published
2020
Full Text
View/download PDF

44. Evolución de la resistencia antimicrobiana en aislados clínicos de Pseudomonas aeruginosa productores de infecciones invasivas en el sur de España

Author

Fernández-Cuenca, Felipe, primary, Martínez-Martínez, Luis, additional, Pascual, Álvaro, additional, Garduño, Eugenio, additional, Hernández Pérez, Purificación, additional, Muñoz Sanz, José Román, additional, González Velasco, Carmen, additional, Rodríguez, Saray, additional, Navarro Marí, José M., additional, Dolores Rojo Martín, María, additional, Álvarez Estévez, Marta, additional, Peña Monje, Alejandro, additional, Sánchez Yebra, Waldo, additional, Roldán Fontana, Carolina, additional, Martín Hita, Lina, additional, Clavijo Frutos, Encarnación, additional, Gracia Ortega, María, additional, Palop Borrás, Begoña, additional, Bermúdez Ruiz, Pilar, additional, Antonio Lepe, José, additional, Aznar, Javier, additional, Carmen Domínguez, M., additional, Gracia Ahufinger, Irene, additional, Rodríguez, Fernando, additional, Domínguez Castaño, Ana, additional, Rodríguez Iglesias, Manuel, additional, Galán Sánchez, Fátima, additional, Dolores López Prieto, M., additional, Sánchez Calvo, Juan Manuel, additional, López Barba, José Luis, additional, and Martínez Rubio, Carmen, additional

Published
2020
Full Text
View/download PDF

46. First report of a canine morbillivirus infection in a giant anteater ( Myrmecophaga tridactyla ) in Brazil

Author

Debesa Belizário Granjeiro, Melissa, primary, Lima Kavasaki, Mayara, additional, Morgado, Thais O., additional, Avelino Dandolini Pavelegini, Lucas, additional, Alves de Barros, Marisol, additional, Fontana, Carolina, additional, Assis Bianchini, Mateus, additional, Oliveira Souza, Aneliza, additional, Gonçalves Lima Oliveira Santos, Amanda R., additional, Lunardi, Michele, additional, Colodel, Edson M., additional, Aguiar, Daniel M., additional, and Jorge Mendonça, Adriane, additional

Published
2020
Full Text
View/download PDF

47. Structure Elucidation of Triterpenoid Saponins Found in an Immunoadjuvant Preparation of Quillaja brasiliensis Using Mass Spectrometry and 1 H and 13 C NMR Spectroscopy.

Author

Wallace, Federico, Fontana, Carolina, Ferreira, Fernando, and Olivaro, Cristina

Subjects
*NUCLEAR magnetic resonance spectroscopy, *TRITERPENOID saponins, *SAPONINS, *ACYL group, *ISOMERS, *MOIETIES (Chemistry)
Abstract

An immunoadjuvant preparation (named Fraction B) was obtained from the aqueous extract of Quillaja brasiliensis leaves, and further fractionated by consecutive separations with silica flash MPLC and reverse phase HPLC. Two compounds were isolated, and their structures elucidated using a combination of NMR spectroscopy and mass spectrometry. One of these compounds is a previously undescribed triterpene saponin (Qb1), which is an isomer of QS-21, the unique adjuvant saponin employed in human vaccines. The other compound is a triterpene saponin previously isolated from Quillaja saponaria bark, known as S13. The structure of Qb1 consists of a quillaic acid residue substituted with a β-d-Galp-(1→2)-[β-d-Xylp-(1→3)]-β-d-GlcpA trisaccharide at C3, and a β-d-Xylp-(1→4)-α-l-Rhap-(1→2)-[α-l-Arap-(1→3)]-β-d-Fucp moiety at C28. The oligosaccharide at C28 was further substituted at O4 of the fucosyl residue with an acyl group capped with a β-d-Xylp residue. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

48. Preparation and mechanistic studies of 2-substituted Bisthiazolidines by imine exchange

Author

Martínez, Verónica, Villamil, Valentina, Duarte, Diego, Saiz, Cecilia, Davyt, Danilo, Fontana, Carolina, Veiga, Nicolás, and Mahler, Graciela

Subjects
Article
Abstract

Bisthiazolidines (BTZ) are bicyclic compounds considered penicillin analogs that inhibit the full range of Metallo-β-Lactamases (MBLs) and potentiate β-lactam activity against resistant bacteria. Herein we present a new methodology to prepare 2-substituted bisthiazolidines by aldehyde exchange. Thirteen new bisthiazolidines were prepared using this methodology, with yields ranged from 31 to 75%. The reaction is based on in situ imines formation, which are able to exchange side chains. The reaction intermediates were studied based on NMR experiments and a key imine 1b-II could be detected in the reaction mixture. Furthermore, a DFT computational analysis was performed to gain insights into the reaction mechanism, allowing us to unveil the different pathways and their activation barriers within the synthetic route. The results suggest that the most favorable route involve the formation of the thiazolidine 1b-III by i) a N-assisted N-C bond cleavage, and ii) a thiol-mediated 5 endo-trig cyclization followed by a C-N bond cleavage. In contrast with previously reported evidence, the imine metathesis was discarded as a plausible pathway. Finally, the reaction of 1b-III with aldehyde 2a leads to bicycle 4a via the iminium ion 1b-V.

Published
2020

50. Elucidation of the O-antigen structure of Escherichia coli O63

Author

Ståhle, Jonas, Fontana, Carolina, Weintraub, Andrej, Widmalm, Göran, Ståhle, Jonas, Fontana, Carolina, Weintraub, Andrej, and Widmalm, Göran

Abstract

The structure of the O-antigen polysaccharide (PS) from the Shiga-toxin producing Escherichia coli O63 has been elucidated using a combination of bioinformatics, component analyses and NMR spectroscopy. The O-antigen is comprised of tetrasaccharide repeating units with the following structure: 2)--d-Quip3N(d-allo-ThrAc)-(12)--d-Ribf-(14)--d-Galp-(13)--d-GlcpNAc-(1 in which the N-acetylated d-allo-threonine is amide-linked to position 3 of the 3-amino-3-deoxy-d-Quip sugar residue. The presence of a predicted flippase and polymerase encoded in the O63 gene cluster is consistent with the Wzx/Wzy biosynthetic pathway and consequently the biological repeating unit has likely an N-acetyl-d-glucosamine residue at its reducing end. A bioinformatics approach based on predictive glycosyltransferase function present in ECODAB (E. coli O-antigen database) suggested the structural element -d-Galp-(13)-d-GlcpNAc in the O-antigen. Notably, multiple gene sequence alignment of fdtA and qdtA from E. coli to that in E. coli O63 resulted in discrimination between the two, confirmation of the latter in E. coli O63, and consequently, together with qdtB, biosynthesis of dTDP-d-Quip3N. The E. coli O63 O-antigen polysaccharide differs in two aspects from that of E. coli O114 where the latter carries instead an l-serine residue, and the glycosidic linkage positions to and from the Quip3N residue are both changed. The structural characterization of the O63 antigen repeat supports the predicted functional assignment of the O-antigen cluster genes.

Published
2019
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results