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Background and Objective: To evaluate the impact of lockdown on weight gain, physical activity level, adherence to treatment, and flu and pneumococcal immunization in patients with type 2 diabetes (DM2). Method: Patients with DM2 were followed by telephone after at least 100 days of the start of the lockdown. Two regions were compared, grouped in relation to the number of cases: region 1, more than 150 cases/100,000 population, and region 2, less than 150 cases/100,000 population. Results: 454 patients with DM2 were contacted. Forty-two percent of the patients reported weight gain and 7% reported having gained more than 5 kg. In relation to physical activity, a lower average was observed in region 1 (367.5 [0-5698] MET/week) than in region 2 (720 [0-7066] MET/week) (p = 0.0009). Adherence to drug treatment decreased overall but increased in the areas of greatest viral circulation. On the other hand, there was an increase in influenza and pneumococcal vaccination, reaching coverage levels of 80 % and 70 %, respectively. Conclusions: In a population at high cardiovascular risk and with a high prevalence of overweight/obesity, the lockdown was associated weight gain and lower physical activity, which could be detrimental to the cardiovascular health of patients with DM2. On the other hand, some positive aspects were observed, such as increased immunizations and increased adherence in the most affected areas. [ABSTRACT FROM AUTHOR]

Copyright of Revista de Nefrología Diálisis y Trasplante is the property of Asociacion Regional de Dialisis y Transplantes Regionale and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Archivos de Cardiología de México is the property of Publicidad Permanyer SLU and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Abstract Background The determination of coronary flow reserve (CFR) is an essential concept at the moment of decision-making in ischemic heart disease. There are several direct and indirect tests to evaluate this parameter. In this sense, dobutamine stress echocardiography is one of the pharmacological method most commonly used worldwide. It has been previously demonstrated that CFR can be determined by this technique. Despite our wide experience with dobutamine stress echocardiography, we ignored the necessary heart rate to consider sufficient the test for the analysis of CFR. For this reason, our main goal was to determine the velocity of coronary flow in each stage of dobutamine stress echocardiography and the heart rate value necessary to double the baseline values of coronary flow velocity in the territory of the left anterior descending (LAD) coronary artery. Methods A total of 33 consecutive patients were analyzed. The patients included had low risk for coronary artery disease. All the participants underwent dobutamine stress echocardiography and coronary artery flow velocity was evaluated in the distal segment of LAD coronary artery using transthoracic color-Doppler echocardiography. Results The feasibility of determining CFR in the territory of the LAD during dobutamine stress echocardiography was high: 31/33 patients (94%). Mean CFR was 2.67 at de end of dobutamine test. There was an excellent concordance between delta HR (difference between baseline HR and maximum HR) and the increase in the CFR (correlation coefficient 0.84). In this sense, we found that when HR increased by 50 beats, CFR was ≥ 2 (CI 93-99.2%). In addition, 96.4% of patients reached a CFR ≥ 2 (IC 91.1 - 99%) at 75% of their predicted maximum heart rate. Conclusions We found that the feasibility of dobutamine stress echocardiography to determine CFR in the territory of the LAD coronary artery was high. In this study, it was necessary to achieve a difference of 50 bpm from baseline HR or at least 75% of the maximum predicted heart rate to consider sufficient the test for the analysis of CFR.

Copyright of Revista Argentina de Cardiología is the property of Sociedad Argentina de Cardiologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)