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15 results on '"Forte, Vittorio"'

2. Predictors of Early Thrombotic Events in Adult Patients with Acute Myeloid Leukemia: A Real-World Experience

Author

Paterno, Giovangiacinto, primary, Palmieri, Raffaele, additional, Forte, Vittorio, additional, Del Prete, Valentina, additional, Gurnari, Carmelo, additional, Guarnera, Luca, additional, Mallegni, Flavia, additional, Pascale, Maria Rosaria, additional, Buzzatti, Elisa, additional, Mezzanotte, Valeria, additional, Cerroni, Ilaria, additional, Savi, Arianna, additional, Buccisano, Francesco, additional, Maurillo, Luca, additional, Venditti, Adriano, additional, and Del Principe, Maria Ilaria, additional

Published
2022
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4. In BCR-ABL1 Positive B-Cell Acute Lymphoblastic Leukemia, Steroid Therapy Induces Hypofibrinogenemia

Author

Buzzatti, Elisa, primary, Forghieri, Fabio, additional, Paterno, Giovangiacinto, additional, Marchesi, Francesco, additional, Sarlo, Chiara, additional, Giglio, Fabio, additional, Fracchiolla, Nicola, additional, Sciumè, Mariarita, additional, Palmieri, Raffaele, additional, Esposito, Fabiana, additional, Guarnera, Luca, additional, Mercante, Lisa, additional, Pascale, Maria Rosaria, additional, Mallegni, Flavia, additional, Savi, Arianna, additional, Forte, Vittorio, additional, Maurillo, Luca, additional, Buccisano, Francesco, additional, Venditti, Adriano, additional, and Del Principe, Maria Ilaria, additional

Published
2022
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7. Pattern of Central Nervous System (CNS) Involvement in Adult Acute Myeloid Leukemia (AML) and Its Impact on Outcome

Author

Del Principe, Maria Ilaria, primary, Buccisano, Francesco, additional, Soddu, Stefano, additional, Maurillo, Luca, additional, Cefalo, Mariagiovanna, additional, Piciocchi, Alfonso, additional, Paterno, Giovangiacinto, additional, Sarlo, Chiara, additional, De Angelis, Gottardo, additional, Forte, Vittorio, additional, Irno Consalvo, Maria, additional, Fraboni, Daniela, additional, De Bellis, Eleonora, additional, Zizzari, Annagiulia, additional, Divona, Mariadomenica, additional, Sconocchia, Giuseppe, additional, Voso, Maria Teresa, additional, Del Poeta, Giovanni, additional, Lo Coco, Francesco, additional, Amadori, Sergio, additional, Arcese, William, additional, and Venditti, Adriano, additional

Published
2016
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12. Multidimensional Flow Cytometry for Detection of Minimal Residual Disease in Acute Myeloid Leukemia

Author

Venditti, Adriano, primary, Maurillo, Luca, additional, Buccisano, Francesco, additional, Tamburini, Anna, additional, Del Poeta, Giovanni, additional, Ilaria Del Principe, Maria, additional, Panetta, Paola, additional, Irno Consalvo, Maria, additional, Mazzone, Carla, additional, Tendas, Andrea, additional, Trawinska, Margherita, additional, Forte, Vittorio, additional, and Amadori, Sergio, additional

Published
2003
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14. Characterization of a novel CYP2C9gene mutation and structural bioinformatic protein analysis in a warfarin hypersensitive patient

Author

Ciccacci, Cinzia, Falconi, Mattia, Paolillo, Nicoletta, Oteri, Francesco, Forte, Vittorio, Novelli, Giuseppe, Desideri, Alessandro, and Borgiani, Paola

Abstract

Warfarin (coumadin) is a worldwide-prescribed anticoagulant for the long-term treatment and prevention of thromboembolic events, presenting a great interindividual variability in the required dose. It is known that both environmental and genetic factors influence the dose necessary for the therapeutic effect. Herein we describe a pharmacogenetic study conducted on an Italian patient with warfarin hypersensitivity, who required a very low dosage to achieve therapeutic anticoagulation effect. We genotyped common polymorphisms in VKORC1, CYP2C9, and CYP4F2genes, known to be involved in warfarin dosing. As the patient resulted in a mixture of low-dosing and high-dosing polymorphic variants, we searched for rare mutations by direct sequencing of the same genes. We identified in the CYP2C9gene, a novel mutation in heterozygote status, c.374G>T, which produces the Arg125Leu substitution. We have observed, through an electrostatic analysis, that the new mutation produces an electrostatic alteration on the cytochrome surface.

Published
2011

15. Groundwater flow process in the active volcanic system of Ischia Island (Italy)

Author

Fabbrocino S., Giardino A., Marino L., de Vita S., Di Vito M. A., Marotta E., Avino R., Carandente A., Belviso P., Todisco F., AA.VV., Alfonso Corniello, Emilio Cuoco, Paolo Fabbri, Giovanni Forte, Vittorio Paolucci, Vincenzo Piscopo, Dario Tedesco, Stefano Viaroli, Fabbrocino, S., Giardino, A., Marino, L., de Vita, S., Di Vito, M. A., Marotta, E., Avino, R., Carandente, A., Belviso, P., and Todisco, F.

Subjects
Ischia Island, Geothermal resource, Volcanic aquifer, Thermal water
Abstract

The volcanic system of Ischia is characterized by an intense hydrothermal activity, documented since the early 16th century by the study of Iasolino (1588), which represents the first systematic analysis of the thermal springs of the island for therapeutic purposes. Later studies partially contributed to the enhancement of knowledge on the volcanic, hydrogeological and hydrothermal features of the island, highlighting the strong interaction between hydrothermal flowpaths and volcano- tectonic processes. The reconstruction of the interplay between hydrothermal and magmatic system becomes, therefore, a fundamental element for territorial planning, not only in terms of management of the huge water and geothermal resource, but also in a perspective of prevention and mitigation of volcanic risk. Thermal springs, fumaroles and mud deposits give beginning clues about deep hydrothermal conditions. Till now at Ischia, the local geochemical characterization of fluids and groundwater has been used for the definition of the origin and structure of the hydrothermal system as a whole, as the hydrogeological information is incomplete. However, volcanic hydrothermal systems, such as that characterizes the island of Ischia, are particularly difficult to analyze and outline, as the groundwater resources are the result of a complex and dynamic mixing among meteoric water, sea water and deep fluids. In such cases, the need for an interdisciplinary approach is evident, involving knowledge and research methods ranging from geology to volcanology, geophysics, geochemistry and hydrogeology. With particular reference to the functional and structural representation of the geothermal system of the Ischia island and the resulting correlations with the volcano-tectonic processes, the examination of previous information highlights the need to update and improve the knowledge on groundwater hydrodynamics and mineralization processes. Therefore, the present study aims at a strongly interdisciplinary action that, starting from the design and implementation of a database on the existing geological/volcanological and hydrogeological information, will contribute to highlight the critical issues, define an operating scheme of the hydro-geo-thermal system of the island of Ischia, and upgrade its hydrogeological, geochemical and volcanic monitoring system. The preliminary results improved the definition of the hydrogeological complexes and advanced knowledge of the groundwater flow conditions.

Published
2020

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