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48 results on '"Fournier, Laure S."'

1. METhodological RadiomICs Score (METRICS): a quality scoring tool for radiomics research endorsed by EuSoMII

Author

Kocak, Burak, Akinci D’Antonoli, Tugba, Mercaldo, Nathaniel, Alberich-Bayarri, Angel, Baessler, Bettina, Ambrosini, Ilaria, Andreychenko, Anna E., Bakas, Spyridon, Beets-Tan, Regina G. H., Bressem, Keno, Buvat, Irene, Cannella, Roberto, Cappellini, Luca Alessandro, Cavallo, Armando Ugo, Chepelev, Leonid L., Chu, Linda Chi Hang, Demircioglu, Aydin, deSouza, Nandita M., Dietzel, Matthias, Fanni, Salvatore Claudio, Fedorov, Andrey, Fournier, Laure S., Giannini, Valentina, Girometti, Rossano, Groot Lipman, Kevin B. W., Kalarakis, Georgios, Kelly, Brendan S., Klontzas, Michail E., Koh, Dow-Mu, Kotter, Elmar, Lee, Ho Yun, Maas, Mario, Marti-Bonmati, Luis, Müller, Henning, Obuchowski, Nancy, Orlhac, Fanny, Papanikolaou, Nikolaos, Petrash, Ekaterina, Pfaehler, Elisabeth, Pinto dos Santos, Daniel, Ponsiglione, Andrea, Sabater, Sebastià, Sardanelli, Francesco, Seeböck, Philipp, Sijtsema, Nanna M., Stanzione, Arnaldo, Traverso, Alberto, Ugga, Lorenzo, Vallières, Martin, van Dijk, Lisanne V., van Griethuysen, Joost J. M., van Hamersvelt, Robbert W., van Ooijen, Peter, Vernuccio, Federica, Wang, Alan, Williams, Stuart, Witowski, Jan, Zhang, Zhongyi, Zwanenburg, Alex, and Cuocolo, Renato

Published
2024
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12. Bone Metastases Are Measurable: The Role of Whole-Body MRI and Positron Emission Tomography

Author

Oprea-Lager, Daniela E., primary, Cysouw, Matthijs C.F., additional, Boellaard, Ronald, additional, Deroose, Christophe M., additional, de Geus-Oei, Lioe-Fee, additional, Lopci, Egesta, additional, Bidaut, Luc, additional, Herrmann, Ken, additional, Fournier, Laure S., additional, Bäuerle, Tobias, additional, deSouza, Nandita M., additional, and Lecouvet, Frederic E., additional

Published
2021
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13. Bone Metastases Are Measurable: The Role of Whole-Body MRI and Positron Emission Tomography.

Author

UCL - SSS/IREC/IMAG - Pôle d'imagerie médicale, UCL - (SLuc) Service de radiologie, Oprea-Lager, Daniela E, Cysouw, Matthijs C F, Boellaard, Ronald, Deroose, Christophe M, de Geus-Oei, Lioe-Fee, Lopci, Egesta, Bidaut, Luc, Herrmann, Ken, Fournier, Laure S, Bäuerle, Tobias, deSouza, Nandita M, Lecouvet, Frederic E, UCL - SSS/IREC/IMAG - Pôle d'imagerie médicale, UCL - (SLuc) Service de radiologie, Oprea-Lager, Daniela E, Cysouw, Matthijs C F, Boellaard, Ronald, Deroose, Christophe M, de Geus-Oei, Lioe-Fee, Lopci, Egesta, Bidaut, Luc, Herrmann, Ken, Fournier, Laure S, Bäuerle, Tobias, deSouza, Nandita M, and Lecouvet, Frederic E

Abstract

Metastatic tumor deposits in bone marrow elicit differential bone responses that vary with the type of malignancy. This results in either sclerotic, lytic, or mixed bone lesions, which can change in morphology due to treatment effects and/or secondary bone remodeling. Hence, morphological imaging is regarded unsuitable for response assessment of bone metastases and in the current Response Evaluation Criteria In Solid Tumors 1.1 (RECIST1.1) guideline bone metastases are deemed unmeasurable. Nevertheless, the advent of functional and molecular imaging modalities such as whole-body magnetic resonance imaging (WB-MRI) and positron emission tomography (PET) has improved the ability for follow-up of bone metastases, regardless of their morphology. Both these modalities not only have improved sensitivity for visual detection of bone lesions, but also allow for objective measurements of bone lesion characteristics. WB-MRI provides a global assessment of skeletal metastases and for a one-step "all-organ" approach of metastatic disease. Novel MRI techniques include diffusion-weighted imaging (DWI) targeting highly cellular lesions, dynamic contrast-enhanced MRI (DCE-MRI) for quantitative assessment of bone lesion vascularization, and multiparametric MRI (mpMRI) combining anatomical and functional sequences. Recommendations for a homogenization of MRI image acquisitions and generalizable response criteria have been developed. For PET, many metabolic and molecular radiotracers are available, some targeting tumor characteristics not confined to cancer type (e.g. F-FDG) while other targeted radiotracers target specific molecular characteristics, such as prostate specific membrane antigen (PSMA) ligands for prostate cancer. Supporting data on quantitative PET analysis regarding repeatability, reproducibility, and harmonization of PET/CT system performance is available. Bone metastases detected on PET and MRI can be quantitatively assessed using validated methodologies, both on a w

Published
2021

19. Diagnostic Algorithm to Differentiate Benign Atypical Leiomyomas from Malignant Uterine Sarcomas with Diffusion-weighted MRI

Author

Abdel Wahab, Cendos, primary, Jannot, Anne-Sophie, additional, Bonaffini, Pietro A., additional, Bourillon, Camille, additional, Cornou, Caroline, additional, Lefrère-Belda, Marie-Aude, additional, Bats, Anne-Sophie, additional, Thomassin-Naggara, Isabelle, additional, Bellucci, Alexandre, additional, Reinhold, Caroline, additional, and Fournier, Laure S., additional

Published
2020
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20. Involvement of radiologists in oncologic multidisciplinary team meetings: an international survey by the European Society of Oncologic Imaging

Author

Neri, Emanuele, primary, Gabelloni, Michela, additional, Bäuerle, Tobias, additional, Beets-Tan, Regina, additional, Caruso, Damiano, additional, D’Anastasi, Melvin, additional, Dinkel, Julien, additional, Fournier, Laure S, additional, Gourtsoyianni, Sofia, additional, Hoffmann, Ralf-Thorsten, additional, Mayerhöfer, Marius Erik, additional, Regge, Daniele, additional, Schlemmer, Heinz Peter, additional, and Laghi, Andrea, additional

Published
2020
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21. Ovarian-Adnexal Reporting Data System Magnetic Resonance Imaging (O-RADS MRI) Score for Risk Stratification of Sonographically Indeterminate Adnexal Masses

Author

Thomassin-Naggara, Isabelle, primary, Poncelet, Edouard, additional, Jalaguier-Coudray, Aurelie, additional, Guerra, Adalgisa, additional, Fournier, Laure S., additional, Stojanovic, Sanja, additional, Millet, Ingrid, additional, Bharwani, Nishat, additional, Juhan, Valerie, additional, Cunha, Teresa M., additional, Masselli, Gabriele, additional, Balleyguier, Corinne, additional, Malhaire, Caroline, additional, Perrot, Nicolas F., additional, Sadowski, Elizabeth A., additional, Bazot, Marc, additional, Taourel, Patrice, additional, Porcher, Raphaël, additional, Darai, Emile, additional, Reinhold, Caroline, additional, and Rockall, Andrea G., additional

Published
2020
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22. Pitfalls in Imaging For Advanced Ovarian Cancer

Author

Fournier, Laure S., primary, Bennani, Souhail, additional, Bats, Anne Sophie, additional, Rousseau, Caroline, additional, Bensaid, Cherazade, additional, Lecuru, Fabrice, additional, and Chamming׳s, Foucauld, additional

Published
2015
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24. Aggressive Adenoid Cystic Carcinoma With Asymptomatic Spinal Cord Compression Revealed By A 'Curtain Sign'

Author

Thariat, Juliette, Fournier, Laure S., Badoual, Cécile, Marcy, Pierre-Yves, Housset, Martin, Thariat, Juliette, Fournier, Laure S., Badoual, Cécile, Marcy, Pierre-Yves, and Housset, Martin

Abstract

The author presents a case with an unusually aggressive evolution of an adenoid cystic carcinoma of the head and neck. The patient presented with sciatica one year after initial diagnosis. She was otherwise asymptomatic. Complete work-up for bone involvement, included bone scan and MRI. The patient had asymptomatic thoracic (T5) vertebral metastasis revealed by a typical curtain sign on MRI. She benefited from radiotherapy and did not develop respiratory distress, paraplegia or pain but died of other metastases.

Published
2008

25. Multiparametric optical and MR imaging demonstrate inhibition of tumor angiogenesis natural history by mural cell therapy

Author

Faye, Nathalie, primary, Clément, Olivier, additional, Balvay, Daniel, additional, Fitoussi, Victor, additional, Pidial, Laetitia, additional, Sandoval, Federico, additional, Autret, Gwennhael, additional, Silvestre, Jean Sébastien, additional, Dean, Carole Leré, additional, Alison, Marianne, additional, and Fournier, Laure S., additional

Published
2013
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44. Bone metastases are measurable: the role of whole-body MRI and positron emission tomography

Author

Oprea-Lager, Daniela, Cysouw, Matthijs C., Boellard, Ronald, Deroose, Christophe M., De Geus-Oei, Lioe-Fee, Lopci, Egesta, Bidaut, Luc, Herrman, Ken, Fournier, Laure S., Bauerle, Tobias, DeSouza, Nandita M., Lecouvet, Frederic, Oprea-Lager, Daniela, Cysouw, Matthijs C., Boellard, Ronald, Deroose, Christophe M., De Geus-Oei, Lioe-Fee, Lopci, Egesta, Bidaut, Luc, Herrman, Ken, Fournier, Laure S., Bauerle, Tobias, DeSouza, Nandita M., and Lecouvet, Frederic

Abstract

Metastatic tumor deposits in bone marrow elicit differential bone responses that vary with the type of malignancy. This results in either sclerotic, lytic, or mixed bone lesions, which can change in morphology due to treatment effects and/or secondary bone remodeling. Hence, morphological imaging is regarded unsuitable for response assessment of bone metastases and in the current Response Evaluation Criteria In Solid Tumors 1.1 (RECIST1.1) guideline bone metastases are deemed unmeasurable. Nevertheless, the advent of functional and molecular imaging modalities such as whole-body magnetic resonance imaging (WB-MRI) and positron-emission tomography (PET) has improved the ability for follow-up of bone metastases, regardless of their morphology. Both these modalities not only have improved sensitivity for visual detection of bone lesions, but also allow for objective measurements of bone lesion characteristics. WB-MRI provides a global assessment of skeletal metastases and for a one-step “all-organ” approach of metastatic disease. Novel MRI techniques include diffusion-weighted imaging (DWI) targeting highly cellular lesions, dynamic contrast-enhanced MRI (DCE-MRI) for quantitative assessment of bone lesion vascularization, and multiparametric MRI (mpMRI) combining anatomical and functional sequences. Recommendations for a homogenization of MRI image acquisitions and generalizable response criteria have been developed. For PET, many metabolic and molecular radiotracers are available, some targeting tumor characteristics not confined to cancer type (e.g. 18F-FDG) while other targeted radiotracers target specific molecular characteristics, such as prostate specific membrane antigen (PSMA) ligands for prostate cancer. Supporting data on quantitative PET analysis regarding repeatability, reproducibility, and harmonization of PET/CT system performance is available. Bone metastases detected on PET and MRI can be quantitatively assessed using validated methodologies, both on a

46. New insights into the management of renal cell cancer.

Author

Pécuchet N, Fournier LS, and Oudard S

Subjects
Carcinoma, Renal Cell metabolism, Humans, Kidney Neoplasms metabolism, Neoplasm Proteins metabolism, Antineoplastic Agents therapeutic use, Carcinoma, Renal Cell drug therapy, Kidney Neoplasms drug therapy, Molecular Targeted Therapy, Neoplasm Proteins antagonists & inhibitors
Abstract

Kidney cancer is composed of several bio-histological entities. The most frequent type, clear-cell carcinoma, is not homogenous regarding gene mutations or transcriptomic profiles, but the biologic classifications are not yet mature. Therefore, biologically driven strategies of treatment have not yet been developed in the clinical setting. The choice of first-line agent currently depends on the prognostic criteria published by Motzer et al. [J Clin Oncol 1999;17:2530-2540] and recently by Heng et al. [J Clin Oncol 2009;27:5794-5799], with anti-vascular endothelial growth factor (VEGF) therapies for good- or intermediate-prognosis groups and anti-mammalian target of rapamycin (mTOR) for poor-risk patients. In the past years, biological changes leading to resistance to targeted agents have been widely investigated. Discoveries resulted in the development of second-generation VEGF receptor tyrosine kinase inhibitors, characterized by an improved potency and selectivity. Besides, co-inhibition of signalling pathways mediating resistance to anti-VEGF are being developed targeting fibroblast growth factor and c-Met. Dual mTOR/phosphatidylinositol 3-kinase inhibitors have greater efficacy than rapalogs in preclinical models and are being investigated in early clinical trials. In conclusion, the changing landscape in the biology and treatment of kidney cancer offers new opportunities for clinicians to treat patients, but, due to relatively high costs, the use of targeted therapies will likely be strongly controlled by health authorities., (Copyright © 2012 S. Karger AG, Basel.)

Published
2013
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47. Case report. Pyothorax-associated lymphoma: Diagnosis at percutaneous core biopsy with CT guidance.

Author

Brun V, Revel MP, Danel C, Fournier LS, Souilamas R, and Frija G

Subjects
Aged, Aged, 80 and over, Antigens, CD20 analysis, Collapse Therapy, Empyema, Pleural diagnostic imaging, Humans, Lung diagnostic imaging, Lung pathology, Lung Neoplasms diagnostic imaging, Lymphoma, B-Cell diagnostic imaging, Lymphoma, Non-Hodgkin diagnostic imaging, Male, Opportunistic Infections diagnostic imaging, Tuberculosis complications, Tuberculosis therapy, Biopsy, Needle, Empyema, Pleural pathology, Lung Neoplasms pathology, Lymphoma, B-Cell pathology, Lymphoma, Non-Hodgkin pathology, Opportunistic Infections pathology, Tomography, X-Ray Computed
Published
2003
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48. Can CT replace bronchoscopy in the detection of the site and cause of bleeding in patients with large or massive hemoptysis?

Author

Revel MP, Fournier LS, Hennebicque AS, Cuenod CA, Meyer G, Reynaud P, and Frija G

Subjects
Adult, Aged, Aged, 80 and over, Bronchoscopy, Chi-Square Distribution, Female, Fiber Optic Technology, Hemoptysis etiology, Hemoptysis therapy, Humans, Male, Middle Aged, Radiography, Thoracic, Retrospective Studies, Hemoptysis diagnostic imaging, Tomography, X-Ray Computed
Abstract

Objective: We assessed the capacity of chest radiography and CT to determine the cause and site of bleeding in patients with either large or massive hemoptysis compared with bronchoscopy., Materials and Methods: We reviewed the chest radiographs, CT scans, and bronchoscopic findings in 80 patients with either large or massive hemoptysis who were admitted to our intensive care unit between January 1995 and June 1999., Results: Findings on chest radiography were normal in only 13% of patients, of whom 70% had bronchiectasis. The chest radiographs revealed the site of bleeding in 46% of the patients and the cause in 35%, most of whom had tuberculosis or tumors. CT was more efficient than bronchoscopy for identifying the cause of bleeding (77% vs 8%, respectively; p < 0.001), whereas the two methods were comparable for identifying the site of bleeding (70% vs 73%, respectively; p = not significant)., Conclusion: These data suggest that CT could replace bronchoscopy as the first-line procedure for screening patients with large and those with massive hemoptysis. However, these results must be confirmed in a prospective multicenter study.

Published
2002
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