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20 results on '"Frau, Ileana"'

6. Presence and activities of clinical research coordinators at Italian Health Care Institutions: A national cross-sectional survey.

Author

Caminiti, Caterina, Maglietta, Giuseppe, Frau, Ileana, Peruzzotti, Giulia, Felisi, Mariagrazia, and van Dijk, Antoinette

Subjects
HEALTH facilities, CLINICAL trials, MEDICAL research, RESEARCH teams, SERVER farms (Computer network management), MULTIVARIABLE testing
Abstract

Background: Clinical Research Coordinators (CRCs) are key members of research teams who ensure rigorous conduction of clinical studies and quality standard compliance. Yet, their roles and responsibilities are still not well defined, and formal recognition of their professional profile is lacking in Italy. This survey of Italian healthcare institutions collected data on centers' research activities number of CRCs and tasks they performed and explored factors associated with CRC employment. Methods: Cross-sectional study using a brief questionnaire. Data were analyzed by means of graphical representations, histogram, scatter, and polar plots. Multivariable linear regression was specified to test the association between the number of CRCs and a subset of factors. Results: Data collection took place from February to December 2020. 62/143 institutions (43.4%) responded. Median number of ongoing studies reported by centers was 65 (IQR 29–205); of these, median of sponsored and interventional studies was 32 and 35, respectively. Median number of CRCs employed at each center was 6 (IQR 2–9). The frequency with which activities were reported to be performed by CRCs overlapped with those of Data Managers. Linear multivariable regression analysis revealed a statistically significant association between the number of employed CRCs and the number of sponsored studies (P = 0.01), but not with the total number of studies, geographical location, or institution type. Conclusions: The association between industry funding and the number of CRCs observed in this study should be further explored to understand the direction of this relationship and to verify whether this may influence compliance with quality standards. [ABSTRACT FROM AUTHOR]

Published
2022
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10. Synthesis and biological evaluation of non-glucose glycoconjugated N-hydroyxindole class LDH inhibitors as anticancer agents

Author

Di Bussolo, Valeria, primary, Calvaresi, Emilia C., additional, Granchi, Carlotta, additional, Del Bino, Linda, additional, Frau, Ileana, additional, Dasso Lang, Maria Chiara, additional, Tuccinardi, Tiziano, additional, Macchia, Marco, additional, Martinelli, Adriano, additional, Hergenrother, Paul J., additional, and Minutolo, Filippo, additional

Published
2015
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