213 results on '"Freeman, Samuel S."'
Search Results
2. Genomic and transcriptomic analysis of checkpoint blockade response in advanced non-small cell lung cancer
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Ravi, Arvind, Hellmann, Matthew D., Arniella, Monica B., Holton, Mark, Freeman, Samuel S., Naranbhai, Vivek, Stewart, Chip, Leshchiner, Ignaty, Kim, Jaegil, Akiyama, Yo, Griffin, Aaron T., Vokes, Natalie I., Sakhi, Mustafa, Kamesan, Vashine, Rizvi, Hira, Ricciuti, Biagio, Forde, Patrick M., Anagnostou, Valsamo, Riess, Jonathan W., Gibbons, Don L., Pennell, Nathan A., Velcheti, Vamsidhar, Digumarthy, Subba R., Mino-Kenudson, Mari, Califano, Andrea, Heymach, John V., Herbst, Roy S., Brahmer, Julie R., Schalper, Kurt A., Velculescu, Victor E., Henick, Brian S., Rizvi, Naiyer, Jänne, Pasi A., Awad, Mark M., Chow, Andrew, Greenbaum, Benjamin D., Luksza, Marta, Shaw, Alice T., Wolchok, Jedd, Hacohen, Nir, Getz, Gad, and Gainor, Justin F.
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- 2023
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3. Identification of transcriptional programs using dense vector representations defined by mutual information with GeneVector
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Ceglia, Nicholas, Sethna, Zachary, Freeman, Samuel S., Uhlitz, Florian, Bojilova, Viktoria, Rusk, Nicole, Burman, Bharat, Chow, Andrew, Salehi, Sohrab, Kabeer, Farhia, Aparicio, Samuel, Greenbaum, Benjamin D., Shah, Sohrab P., and McPherson, Andrew
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- 2023
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4. Personalised progression prediction in patients with monoclonal gammopathy of undetermined significance or smouldering multiple myeloma (PANGEA): a retrospective, multicohort study
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Cowan, Annie, Ferrari, Federico, Freeman, Samuel S, Redd, Robert, El-Khoury, Habib, Perry, Jacqueline, Patel, Vidhi, Kaur, Priya, Barr, Hadley, Lee, David J, Lightbody, Elizabeth, Downey, Katelyn, Argyelan, David, Theodorakakou, Foteini, Fotiou, Despina, Liacos, Christine Ivy, Kanellias, Nikolaos, Chavda, Selina J, Ainley, Louise, Sandecká, Viera, Pospíšilová, Lenka, Minarik, Jiri, Jungova, Alexandra, Radocha, Jakub, Spicka, Ivan, Nadeem, Omar, Yong, Kwee, Hájek, Roman, Kastritis, Efstathios, Marinac, Catherine R, Dimopoulos, Meletios A, Getz, Gad, Trippa, Lorenzo, and Ghobrial, Irene M
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- 2023
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5. In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer
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Dubrot, Juan, Du, Peter P., Lane-Reticker, Sarah Kate, Kessler, Emily A., Muscato, Audrey J., Mehta, Arnav, Freeman, Samuel S., Allen, Peter M., Olander, Kira E., Ockerman, Kyle M., Wolfe, Clara H., Wiesmann, Fabius, Knudsen, Nelson H., Tsao, Hsiao-Wei, Iracheta-Vellve, Arvin, Schneider, Emily M., Rivera-Rosario, Andrea N., Kohnle, Ian C., Pope, Hans W., Ayer, Austin, Mishra, Gargi, Zimmer, Margaret D., Kim, Sarah Y., Mahapatra, Animesh, Ebrahimi-Nik, Hakimeh, Frederick, Dennie T., Boland, Genevieve M., Haining, W. Nicholas, Root, David E., Doench, John G., Hacohen, Nir, Yates, Kathleen B., and Manguso, Robert T.
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- 2022
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6. Landscape of helper and regulatory antitumour CD4+ T cells in melanoma
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Oliveira, Giacomo, Stromhaug, Kari, Cieri, Nicoletta, Iorgulescu, J. Bryan, Klaeger, Susan, Wolff, Jacquelyn O., Rachimi, Suzanna, Chea, Vipheaviny, Krause, Kate, Freeman, Samuel S., Zhang, Wandi, Li, Shuqiang, Braun, David A., Neuberg, Donna, Carr, Steven A., Livak, Kenneth J., Frederick, Dennie T., Fritsch, Edward F., Wind-Rotolo, Megan, Hacohen, Nir, Sade-Feldman, Moshe, Yoon, Charles H., Keskin, Derin B., Ott, Patrick A., Rodig, Scott J., Boland, Genevieve M., and Wu, Catherine J.
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- 2022
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7. Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma
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Pectasides, Eirini, Stachler, Matthew D, Derks, Sarah, Liu, Yang, Maron, Steven, Islam, Mirazul, Alpert, Lindsay, Kwak, Heewon, Kindler, Hedy, Polite, Blase, Sharma, Manish R, Allen, Kenisha, O'Day, Emily, Lomnicki, Samantha, Maranto, Melissa, Kanteti, Rajani, Fitzpatrick, Carrie, Weber, Christopher, Setia, Namrata, Xiao, Shu-Yuan, Hart, John, Nagy, Rebecca J, Kim, Kyoung-Mee, Choi, Min-Gew, Min, Byung-Hoon, Nason, Katie S, O'Keefe, Lea, Watanabe, Masayuki, Baba, Hideo, Lanman, Rick, Agoston, Agoston T, Oh, David J, Dunford, Andrew, Thorner, Aaron R, Ducar, Matthew D, Wollison, Bruce M, Coleman, Haley A, Ji, Yuan, Posner, Mitchell C, Roggin, Kevin, Turaga, Kiran, Chang, Paul, Hogarth, Kyle, Siddiqui, Uzma, Gelrud, Andres, Ha, Gavin, Freeman, Samuel S, Rhoades, Justin, Reed, Sarah, Gydush, Greg, Rotem, Denisse, Davison, Jon, Imamura, Yu, Adalsteinsson, Viktor, Lee, Jeeyun, Bass, Adam J, and Catenacci, Daniel V
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Biological Sciences ,Biomedical and Clinical Sciences ,Genetics ,Clinical Sciences ,Oncology and Carcinogenesis ,Digestive Diseases ,Cancer ,Human Genome ,Genetic Testing ,Good Health and Well Being ,Adenocarcinoma ,Cohort Studies ,Esophageal Neoplasms ,Genomics ,Humans ,Precision Medicine ,Stomach Neoplasms ,Exome Sequencing ,Biochemistry and cell biology ,Oncology and carcinogenesis - Abstract
Gastroesophageal adenocarcinoma (GEA) is a lethal disease where targeted therapies, even when guided by genomic biomarkers, have had limited efficacy. A potential reason for the failure of such therapies is that genomic profiling results could commonly differ between the primary and metastatic tumors. To evaluate genomic heterogeneity, we sequenced paired primary GEA and synchronous metastatic lesions across multiple cohorts, finding extensive differences in genomic alterations, including discrepancies in potentially clinically relevant alterations. Multiregion sequencing showed significant discrepancy within the primary tumor (PT) and between the PT and disseminated disease, with oncogene amplification profiles commonly discordant. In addition, a pilot analysis of cell-free DNA (cfDNA) sequencing demonstrated the feasibility of detecting genomic amplifications not detected in PT sampling. Lastly, we profiled paired primary tumors, metastatic tumors, and cfDNA from patients enrolled in the personalized antibodies for GEA (PANGEA) trial of targeted therapies in GEA and found that genomic biomarkers were recurrently discrepant between the PT and untreated metastases. Divergent primary and metastatic tissue profiling led to treatment reassignment in 32% (9/28) of patients. In discordant primary and metastatic lesions, we found 87.5% concordance for targetable alterations in metastatic tissue and cfDNA, suggesting the potential for cfDNA profiling to enhance selection of therapy.Significance: We demonstrate frequent baseline heterogeneity in targetable genomic alterations in GEA, indicating that current tissue sampling practices for biomarker testing do not effectively guide precision medicine in this disease and that routine profiling of metastatic lesions and/or cfDNA should be systematically evaluated. Cancer Discov; 8(1); 37-48. ©2017 AACR.See related commentary by Sundar and Tan, p. 14See related article by Janjigian et al., p. 49This article is highlighted in the In This Issue feature, p. 1.
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- 2018
8. Genome-scale screens identify factors regulating tumor cell responses to natural killer cells
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Sheffer, Michal, Lowry, Emily, Beelen, Nicky, Borah, Minasri, Amara, Suha Naffar-Abu, Mader, Chris C., Roth, Jennifer A., Tsherniak, Aviad, Freeman, Samuel S., Dashevsky, Olga, Gandolfi, Sara, Bender, Samantha, Bryan, Jordan G., Zhu, Cong, Wang, Li, Tariq, Ifrah, Kamath, Govinda M., Simoes, Ricardo De Matos, Dhimolea, Eugen, Yu, Channing, Hu, Yiguo, Dufva, Olli, Giannakis, Marios, Syrgkanis, Vasilis, Fraenkel, Ernest, Golub, Todd, Romee, Rizwan, Mustjoki, Satu, Culhane, Aedin C., Wieten, Lotte, and Mitsiades, Constantine S.
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- 2021
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9. Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia
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Wang, Lili, Brooks, Angela N, Fan, Jean, Wan, Youzhong, Gambe, Rutendo, Li, Shuqiang, Hergert, Sarah, Yin, Shanye, Freeman, Samuel S, Levin, Joshua Z, Fan, Lin, Seiler, Michael, Buonamici, Silvia, Smith, Peter G, Chau, Kevin F, Cibulskis, Carrie L, Zhang, Wandi, Rassenti, Laura Z, Ghia, Emanuela M, Kipps, Thomas J, Fernandes, Stacey, Bloch, Donald B, Kotliar, Dylan, Landau, Dan A, Shukla, Sachet A, Aster, Jon C, Reed, Robin, DeLuca, David S, Brown, Jennifer R, Neuberg, Donna, Getz, Gad, Livak, Kenneth J, Meyerson, Matthew M, Kharchenko, Peter V, and Wu, Catherine J
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Biological Sciences ,Biomedical and Clinical Sciences ,Oncology and Carcinogenesis ,Clinical Research ,Hematology ,Lymphatic Research ,Human Genome ,Genetics ,Rare Diseases ,Cancer ,Lymphoma ,2.1 Biological and endogenous factors ,Alternative Splicing ,Cell Line ,Tumor ,Dishevelled Proteins ,Gene Expression Profiling ,Gene Expression Regulation ,Neoplastic ,Humans ,Leukemia ,Lymphocytic ,Chronic ,B-Cell ,Mutation ,Phosphoproteins ,RNA Splicing Factors ,Receptors ,Notch ,Signal Transduction ,CLL ,Notch signaling ,RNA sequencing ,SF3B1 ,alternative splicing ,Neurosciences ,Oncology & Carcinogenesis ,Biochemistry and cell biology ,Oncology and carcinogenesis - Abstract
Mutations in SF3B1, which encodes a spliceosome component, are associated with poor outcome in chronic lymphocytic leukemia (CLL), but how these contribute to CLL progression remains poorly understood. We undertook a transcriptomic characterization of primary human CLL cells to identify transcripts and pathways affected by SF3B1 mutation. Splicing alterations, identified in the analysis of bulk cells, were confirmed in single SF3B1-mutated CLL cells and also found in cell lines ectopically expressing mutant SF3B1. SF3B1 mutation was found to dysregulate multiple cellular functions including DNA damage response, telomere maintenance, and Notch signaling (mediated through KLF8 upregulation, increased TERC and TERT expression, or altered splicing of DVL2 transcript, respectively). SF3B1 mutation leads to diverse changes in CLL-related pathways.
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- 2016
10. Characterization of HPV and host genome interactions in primary head and neck cancers
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Parfenov, Michael, Pedamallu, Chandra Sekhar, Gehlenborg, Nils, Freeman, Samuel S, Danilova, Ludmila, Bristow, Christopher A, Lee, Semin, Hadjipanayis, Angela G, Ivanova, Elena V, Wilkerson, Matthew D, Protopopov, Alexei, Yang, Lixing, Seth, Sahil, Song, Xingzhi, Tang, Jiabin, Ren, Xiaojia, Zhang, Jianhua, Pantazi, Angeliki, Santoso, Netty, Xu, Andrew W, Mahadeshwar, Harshad, Wheeler, David A, Haddad, Robert I, Jung, Joonil, Ojesina, Akinyemi I, Issaeva, Natalia, Yarbrough, Wendell G, Hayes, D Neil, Grandis, Jennifer R, El-Naggar, Adel K, Meyerson, Matthew, Park, Peter J, Chin, Lynda, Seidman, JG, Hammerman, Peter S, Kucherlapati, Raju, Ally, Adrian, Balasundaram, Miruna, Birol, Inanc, Bowlby, Reanne, Butterfield, Yaron SN, Carlsen, Rebecca, Cheng, Dean, Chu, Andy, Dhalla, Noreen, Guin, Ranabir, Holt, Robert A, Jones, Steven JM, Lee, Darlene, Li, Haiyan I, Marra, Marco A, Mayo, Michael, Moore, Richard A, Mungall, Andrew J, Robertson, A Gordon, Schein, Jacqueline E, Sipahimalani, Payal, Tam, Angela, Thiessen, Nina, Wong, Tina, Mahadeshwar, Harshad S, Haseley, Psalm, Zeng, Dong, Bristow, Christopher, Hadjipanayis, Angela, Seidman, Jonathan, Akbani, Rehan, Casasent, Tod, Liu, Wenbin, Lu, Yiling, Mills, Gordon, Motter, Thomas, Weinstein, John, Diao, Lixia, Wang, Jing, Fan, You Hong, Liu, Jinze, Wang, Kai, Auman, J Todd, Balu, Saianand, Bodenheimer, Tom, Buda, Elizabeth, Hoadley, Katherine A, and Hoyle, Alan P
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Biological Sciences ,Biomedical and Clinical Sciences ,Bioinformatics and Computational Biology ,Genetics ,Oncology and Carcinogenesis ,Cancer Genomics ,Infectious Diseases ,Cancer ,Dental/Oral and Craniofacial Disease ,Human Genome ,Cervical Cancer ,Women's Health ,Rare Diseases ,Sexually Transmitted Infections ,2.2 Factors relating to the physical environment ,2.1 Biological and endogenous factors ,Base Sequence ,DNA Methylation ,Gene Expression Regulation ,Neoplastic ,Genes ,Neoplasm ,Genome ,Human ,Head and Neck Neoplasms ,Host-Pathogen Interactions ,Humans ,Molecular Sequence Data ,Papillomaviridae ,Virus Integration ,cancer ,head and neck ,papilloma virus ,genome rearrangement ,integration sites ,Cancer Genome Atlas Network - Abstract
Previous studies have established that a subset of head and neck tumors contains human papillomavirus (HPV) sequences and that HPV-driven head and neck cancers display distinct biological and clinical features. HPV is known to drive cancer by the actions of the E6 and E7 oncoproteins, but the molecular architecture of HPV infection and its interaction with the host genome in head and neck cancers have not been comprehensively described. We profiled a cohort of 279 head and neck cancers with next generation RNA and DNA sequencing and show that 35 (12.5%) tumors displayed evidence of high-risk HPV types 16, 33, or 35. Twenty-five cases had integration of the viral genome into one or more locations in the human genome with statistical enrichment for genic regions. Integrations had a marked impact on the human genome and were associated with alterations in DNA copy number, mRNA transcript abundance and splicing, and both inter- and intrachromosomal rearrangements. Many of these events involved genes with documented roles in cancer. Cancers with integrated vs. nonintegrated HPV displayed different patterns of DNA methylation and both human and viral gene expressions. Together, these data provide insight into the mechanisms by which HPV interacts with the human genome beyond expression of viral oncoproteins and suggest that specific integration events are an integral component of viral oncogenesis.
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- 2014
11. Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
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Sade-Feldman, Moshe, Yizhak, Keren, Bjorgaard, Stacey L., Ray, John P., de Boer, Carl G., Jenkins, Russell W., Lieb, David J., Chen, Jonathan H., Frederick, Dennie T., Barzily-Rokni, Michal, Freeman, Samuel S., Reuben, Alexandre, Hoover, Paul J., Villani, Alexandra-Chloé, Ivanova, Elena, Portell, Andrew, Lizotte, Patrick H., Aref, Amir R., Eliane, Jean-Pierre, Hammond, Marc R., Vitzthum, Hans, Blackmon, Shauna M., Li, Bo, Gopalakrishnan, Vancheswaran, Reddy, Sangeetha M., Cooper, Zachary A., Paweletz, Cloud P., Barbie, David A., Stemmer-Rachamimov, Anat, Flaherty, Keith T., Wargo, Jennifer A., Boland, Genevieve M., Sullivan, Ryan J., Getz, Gad, and Hacohen, Nir
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- 2018
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12. Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing
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Viswanathan, Srinivas R., Ha, Gavin, Hoff, Andreas M., Wala, Jeremiah A., Carrot-Zhang, Jian, Whelan, Christopher W., Haradhvala, Nicholas J., Freeman, Samuel S., Reed, Sarah C., Rhoades, Justin, Polak, Paz, Cipicchio, Michelle, Wankowicz, Stephanie A., Wong, Alicia, Kamath, Tushar, Zhang, Zhenwei, Gydush, Gregory J., Rotem, Denisse, Love, J. Christopher, Getz, Gad, Gabriel, Stacey, Zhang, Cheng-Zhong, Dehm, Scott M., Nelson, Peter S., Van Allen, Eliezer M., Choudhury, Atish D., Adalsteinsson, Viktor A., Beroukhim, Rameen, Taplin, Mary-Ellen, and Meyerson, Matthew
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- 2018
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13. The Cancer Genome Atlas Pan-Cancer analysis project
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Chang, Kyle, Creighton, Chad J, Davis, Caleb, Donehower, Lawrence, Drummond, Jennifer, Wheeler, David, Ally, Adrian, Balasundaram, Miruna, Birol, Inanc, Butterfield, Yaron SN, Chu, Andy, Chuah, Eric, Chun, Hye-Jung E, Dhalla, Noreen, Guin, Ranabir, Hirst, Martin, Hirst, Carrie, Holt, Robert A, Jones, Steven JM, Lee, Darlene, Li, Haiyan I, Marra, Marco A, Mayo, Michael, Moore, Richard A, Mungall, Andrew J, Robertson, A Gordon, Schein, Jacqueline E, Sipahimalani, Payal, Tam, Angela, Thiessen, Nina, Varhol, Richard J, Beroukhim, Rameen, Bhatt, Ami S, Brooks, Angela N, Cherniack, Andrew D, Freeman, Samuel S, Gabriel, Stacey B, Helman, Elena, Jung, Joonil, Meyerson, Matthew, Ojesina, Akinyemi I, Pedamallu, Chandra Sekhar, Saksena, Gordon, Schumacher, Steven E, Tabak, Barbara, Zack, Travis, Lander, Eric S, Bristow, Christopher A, Hadjipanayis, Angela, Haseley, Psalm, Kucherlapati, Raju, Lee, Semin, Lee, Eunjung, Luquette, Lovelace J, Mahadeshwar, Harshad S, Pantazi, Angeliki, Parfenov, Michael, Park, Peter J, Protopopov, Alexei, Ren, Xiaojia, Santoso, Netty, Seidman, Jonathan, Seth, Sahil, Song, Xingzhi, Tang, Jiabin, Xi, Ruibin, Xu, Andrew W, Yang, Lixing, Zeng, Dong, Auman, J Todd, Balu, Saianand, Buda, Elizabeth, Fan, Cheng, Hoadley, Katherine A, Jones, Corbin D, Meng, Shaowu, Mieczkowski, Piotr A, Parker, Joel S, Perou, Charles M, Roach, Jeffrey, Shi, Yan, Silva, Grace O, Tan, Donghui, Veluvolu, Umadevi, Waring, Scot, Wilkerson, Matthew D, Wu, Junyuan, Zhao, Wei, Bodenheimer, Tom, Hayes, D Neil, Hoyle, Alan P, Jeffreys, Stuart R, Mose, Lisle E, Simons, Janae V, Soloway, Mathew G, Baylin, Stephen B, Berman, Benjamin P, Bootwalla, Moiz S, Danilova, Ludmila, and Herman, James G
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Biological Sciences ,Genetics ,Precision Medicine ,Human Genome ,Cancer Genomics ,Cancer ,Good Health and Well Being ,Gene Expression Profiling ,Genome ,Humans ,Neoplasms ,Cancer Genome Atlas Research Network ,Medical and Health Sciences ,Developmental Biology ,Agricultural biotechnology ,Bioinformatics and computational biology - Abstract
The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA, protein and epigenetic levels. The resulting rich data provide a major opportunity to develop an integrated picture of commonalities, differences and emergent themes across tumor lineages. The Pan-Cancer initiative compares the first 12 tumor types profiled by TCGA. Analysis of the molecular aberrations and their functional roles across tumor types will teach us how to extend therapies effective in one cancer type to others with a similar genomic profile.
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- 2013
14. Identification and characterization of an alternative cancer-derived PD-L1 splice variant
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Hassounah, Nadia B., Malladi, Venkat S., Huang, Yi, Freeman, Samuel S., Beauchamp, Ellen M., Koyama, Shohei, Souders, Nicholas, Martin, Sunil, Dranoff, Glenn, Wong, Kwok-Kin, Pedamallu, Chandra S., Hammerman, Peter S., and Akbay, Esra A.
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- 2019
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15. Genomic and immune profiling of pre-invasive lung adenocarcinoma
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Chen, Haiquan, Carrot-Zhang, Jian, Zhao, Yue, Hu, Haichuan, Freeman, Samuel S., Yu, Su, Ha, Gavin, Taylor, Alison M., Berger, Ashton C., Westlake, Lindsay, Zheng, Yuanting, Zhang, Jiyang, Ramachandran, Aruna, Zheng, Qiang, Pan, Yunjian, Zheng, Difan, Zheng, Shanbo, Cheng, Chao, Kuang, Muyu, Zhou, Xiaoyan, Zhang, Yang, Li, Hang, Ye, Ting, Ma, Yuan, Gao, Zhendong, Tao, Xiaoting, Han, Han, Shang, Jun, Yu, Ying, Bao, Ding, Huang, Yechao, Li, Xiangnan, Zhang, Yawei, Xiang, Jiaqing, Sun, Yihua, Li, Yuan, Cherniack, Andrew D., Campbell, Joshua D., Shi, Leming, and Meyerson, Matthew
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- 2019
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16. Spatial analysis of human lung cancer reveals organized immune hubs enriched for stem-like CD8 T cells and associated with immunotherapy response
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Chen, Jonathan H., primary, Nieman, Linda T., additional, Spurrell, Maxwell, additional, Jorgji, Vjola, additional, Richieri, Peter, additional, Xu, Katherine H., additional, Madhu, Roopa, additional, Parikh, Milan, additional, Zamora, Izabella, additional, Mehta, Arnav, additional, Nabel, Christopher S., additional, Freeman, Samuel S., additional, Pirl, Joshua D., additional, Lu, Chenyue, additional, Meador, Catherine B., additional, Barth, Jaimie L., additional, Sakhi, Mustafa, additional, Tang, Alexander L., additional, Sarkizova, Siranush, additional, Price, Colles, additional, Fernandez, Nicolas F., additional, Emanuel, George, additional, He, Jiang, additional, Raay, Katrina Van, additional, Reeves, Jason W., additional, Yizhak, Keren, additional, Hofree, Matan, additional, Shih, Angela, additional, Sade-Feldman, Moshe, additional, Boland, Genevieve M., additional, Pelka, Karin, additional, Aryee, Martin, additional, Korsunsky, Ilya, additional, Mino-Kenudson, Mari, additional, Gainor, Justin F., additional, and Hacohen, Nir, additional
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- 2023
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17. Data from KIR3DL3 Is an Inhibitory Receptor for HHLA2 that Mediates an Alternative Immunoinhibitory Pathway to PD1
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Bhatt, Rupal S., primary, Berjis, Abdulla, primary, Konge, Julie C., primary, Mahoney, Kathleen M., primary, Klee, Alyssa N., primary, Freeman, Samuel S., primary, Chen, Chun-Hau, primary, Jegede, Opeyemi A., primary, Catalano, Paul J., primary, Pignon, Jean-Christophe, primary, Sticco-Ivins, Maura, primary, Zhu, Baogong, primary, Hua, Ping, primary, Soden, Jo, primary, Zhu, Jie, primary, McDermott, David F., primary, Arulanandam, Antonio R., primary, Signoretti, Sabina, primary, and Freeman, Gordon J., primary
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- 2023
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18. Supplementary Figures and Tables from KIR3DL3 Is an Inhibitory Receptor for HHLA2 that Mediates an Alternative Immunoinhibitory Pathway to PD1
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Bhatt, Rupal S., primary, Berjis, Abdulla, primary, Konge, Julie C., primary, Mahoney, Kathleen M., primary, Klee, Alyssa N., primary, Freeman, Samuel S., primary, Chen, Chun-Hau, primary, Jegede, Opeyemi A., primary, Catalano, Paul J., primary, Pignon, Jean-Christophe, primary, Sticco-Ivins, Maura, primary, Zhu, Baogong, primary, Hua, Ping, primary, Soden, Jo, primary, Zhu, Jie, primary, McDermott, David F., primary, Arulanandam, Antonio R., primary, Signoretti, Sabina, primary, and Freeman, Gordon J., primary
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- 2023
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19. Table S2 from The Lipogenic Regulator SREBP2 Induces Transferrin in Circulating Melanoma Cells and Suppresses Ferroptosis
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Hong, Xin, primary, Roh, Whijae, primary, Sullivan, Ryan J., primary, Wong, Keith H.K., primary, Wittner, Ben S., primary, Guo, Hongshan, primary, Dubash, Taronish D., primary, Sade-Feldman, Moshe, primary, Wesley, Benjamin, primary, Horwitz, Elad, primary, Boland, Genevieve M., primary, Marvin, Dieuwke L., primary, Bonesteel, Todd, primary, Lu, Chenyue, primary, Aguet, François, primary, Burr, Risa, primary, Freeman, Samuel S., primary, Parida, Laxmi, primary, Calhoun, Katherine, primary, Jewett, Michelle K., primary, Nieman, Linda T., primary, Hacohen, Nir, primary, Näär, Anders M., primary, Ting, David T., primary, Toner, Mehmet, primary, Stott, Shannon L., primary, Getz, Gad, primary, Maheswaran, Shyamala, primary, and Haber, Daniel A., primary
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- 2023
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20. Supplementary Methods from Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma
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Pectasides, Eirini, primary, Stachler, Matthew D., primary, Derks, Sarah, primary, Liu, Yang, primary, Maron, Steven, primary, Islam, Mirazul, primary, Alpert, Lindsay, primary, Kwak, Heewon, primary, Kindler, Hedy, primary, Polite, Blase, primary, Sharma, Manish R., primary, Allen, Kenisha, primary, O'Day, Emily, primary, Lomnicki, Samantha, primary, Maranto, Melissa, primary, Kanteti, Rajani, primary, Fitzpatrick, Carrie, primary, Weber, Christopher, primary, Setia, Namrata, primary, Xiao, Shu-Yuan, primary, Hart, John, primary, Nagy, Rebecca J., primary, Kim, Kyoung-Mee, primary, Choi, Min-Gew, primary, Min, Byung-Hoon, primary, Nason, Katie S., primary, O'Keefe, Lea, primary, Watanabe, Masayuki, primary, Baba, Hideo, primary, Lanman, Rick, primary, Agoston, Agoston T., primary, Oh, David J., primary, Dunford, Andrew, primary, Thorner, Aaron R., primary, Ducar, Matthew D., primary, Wollison, Bruce M., primary, Coleman, Haley A., primary, Ji, Yuan, primary, Posner, Mitchell C., primary, Roggin, Kevin, primary, Turaga, Kiran, primary, Chang, Paul, primary, Hogarth, Kyle, primary, Siddiqui, Uzma, primary, Gelrud, Andres, primary, Ha, Gavin, primary, Freeman, Samuel S., primary, Rhoades, Justin, primary, Reed, Sarah, primary, Gydush, Greg, primary, Rotem, Denisse, primary, Davison, Jon, primary, Imamura, Yu, primary, Adalsteinsson, Viktor, primary, Lee, Jeeyun, primary, Bass, Adam J., primary, and Catenacci, Daniel V., primary
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- 2023
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21. Supplementary Figure Legends from Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma
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Pectasides, Eirini, primary, Stachler, Matthew D., primary, Derks, Sarah, primary, Liu, Yang, primary, Maron, Steven, primary, Islam, Mirazul, primary, Alpert, Lindsay, primary, Kwak, Heewon, primary, Kindler, Hedy, primary, Polite, Blase, primary, Sharma, Manish R., primary, Allen, Kenisha, primary, O'Day, Emily, primary, Lomnicki, Samantha, primary, Maranto, Melissa, primary, Kanteti, Rajani, primary, Fitzpatrick, Carrie, primary, Weber, Christopher, primary, Setia, Namrata, primary, Xiao, Shu-Yuan, primary, Hart, John, primary, Nagy, Rebecca J., primary, Kim, Kyoung-Mee, primary, Choi, Min-Gew, primary, Min, Byung-Hoon, primary, Nason, Katie S., primary, O'Keefe, Lea, primary, Watanabe, Masayuki, primary, Baba, Hideo, primary, Lanman, Rick, primary, Agoston, Agoston T., primary, Oh, David J., primary, Dunford, Andrew, primary, Thorner, Aaron R., primary, Ducar, Matthew D., primary, Wollison, Bruce M., primary, Coleman, Haley A., primary, Ji, Yuan, primary, Posner, Mitchell C., primary, Roggin, Kevin, primary, Turaga, Kiran, primary, Chang, Paul, primary, Hogarth, Kyle, primary, Siddiqui, Uzma, primary, Gelrud, Andres, primary, Ha, Gavin, primary, Freeman, Samuel S., primary, Rhoades, Justin, primary, Reed, Sarah, primary, Gydush, Greg, primary, Rotem, Denisse, primary, Davison, Jon, primary, Imamura, Yu, primary, Adalsteinsson, Viktor, primary, Lee, Jeeyun, primary, Bass, Adam J., primary, and Catenacci, Daniel V., primary
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- 2023
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22. Data from Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma
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Pectasides, Eirini, primary, Stachler, Matthew D., primary, Derks, Sarah, primary, Liu, Yang, primary, Maron, Steven, primary, Islam, Mirazul, primary, Alpert, Lindsay, primary, Kwak, Heewon, primary, Kindler, Hedy, primary, Polite, Blase, primary, Sharma, Manish R., primary, Allen, Kenisha, primary, O'Day, Emily, primary, Lomnicki, Samantha, primary, Maranto, Melissa, primary, Kanteti, Rajani, primary, Fitzpatrick, Carrie, primary, Weber, Christopher, primary, Setia, Namrata, primary, Xiao, Shu-Yuan, primary, Hart, John, primary, Nagy, Rebecca J., primary, Kim, Kyoung-Mee, primary, Choi, Min-Gew, primary, Min, Byung-Hoon, primary, Nason, Katie S., primary, O'Keefe, Lea, primary, Watanabe, Masayuki, primary, Baba, Hideo, primary, Lanman, Rick, primary, Agoston, Agoston T., primary, Oh, David J., primary, Dunford, Andrew, primary, Thorner, Aaron R., primary, Ducar, Matthew D., primary, Wollison, Bruce M., primary, Coleman, Haley A., primary, Ji, Yuan, primary, Posner, Mitchell C., primary, Roggin, Kevin, primary, Turaga, Kiran, primary, Chang, Paul, primary, Hogarth, Kyle, primary, Siddiqui, Uzma, primary, Gelrud, Andres, primary, Ha, Gavin, primary, Freeman, Samuel S., primary, Rhoades, Justin, primary, Reed, Sarah, primary, Gydush, Greg, primary, Rotem, Denisse, primary, Davison, Jon, primary, Imamura, Yu, primary, Adalsteinsson, Viktor, primary, Lee, Jeeyun, primary, Bass, Adam J., primary, and Catenacci, Daniel V., primary
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- 2023
- Full Text
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23. Data from The Lipogenic Regulator SREBP2 Induces Transferrin in Circulating Melanoma Cells and Suppresses Ferroptosis
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Hong, Xin, primary, Roh, Whijae, primary, Sullivan, Ryan J., primary, Wong, Keith H.K., primary, Wittner, Ben S., primary, Guo, Hongshan, primary, Dubash, Taronish D., primary, Sade-Feldman, Moshe, primary, Wesley, Benjamin, primary, Horwitz, Elad, primary, Boland, Genevieve M., primary, Marvin, Dieuwke L., primary, Bonesteel, Todd, primary, Lu, Chenyue, primary, Aguet, François, primary, Burr, Risa, primary, Freeman, Samuel S., primary, Parida, Laxmi, primary, Calhoun, Katherine, primary, Jewett, Michelle K., primary, Nieman, Linda T., primary, Hacohen, Nir, primary, Näär, Anders M., primary, Ting, David T., primary, Toner, Mehmet, primary, Stott, Shannon L., primary, Getz, Gad, primary, Maheswaran, Shyamala, primary, and Haber, Daniel A., primary
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- 2023
- Full Text
- View/download PDF
24. Supplementary Figures 1-4 from Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma
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Pectasides, Eirini, primary, Stachler, Matthew D., primary, Derks, Sarah, primary, Liu, Yang, primary, Maron, Steven, primary, Islam, Mirazul, primary, Alpert, Lindsay, primary, Kwak, Heewon, primary, Kindler, Hedy, primary, Polite, Blase, primary, Sharma, Manish R., primary, Allen, Kenisha, primary, O'Day, Emily, primary, Lomnicki, Samantha, primary, Maranto, Melissa, primary, Kanteti, Rajani, primary, Fitzpatrick, Carrie, primary, Weber, Christopher, primary, Setia, Namrata, primary, Xiao, Shu-Yuan, primary, Hart, John, primary, Nagy, Rebecca J., primary, Kim, Kyoung-Mee, primary, Choi, Min-Gew, primary, Min, Byung-Hoon, primary, Nason, Katie S., primary, O'Keefe, Lea, primary, Watanabe, Masayuki, primary, Baba, Hideo, primary, Lanman, Rick, primary, Agoston, Agoston T., primary, Oh, David J., primary, Dunford, Andrew, primary, Thorner, Aaron R., primary, Ducar, Matthew D., primary, Wollison, Bruce M., primary, Coleman, Haley A., primary, Ji, Yuan, primary, Posner, Mitchell C., primary, Roggin, Kevin, primary, Turaga, Kiran, primary, Chang, Paul, primary, Hogarth, Kyle, primary, Siddiqui, Uzma, primary, Gelrud, Andres, primary, Ha, Gavin, primary, Freeman, Samuel S., primary, Rhoades, Justin, primary, Reed, Sarah, primary, Gydush, Greg, primary, Rotem, Denisse, primary, Davison, Jon, primary, Imamura, Yu, primary, Adalsteinsson, Viktor, primary, Lee, Jeeyun, primary, Bass, Adam J., primary, and Catenacci, Daniel V., primary
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- 2023
- Full Text
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25. Supplementary Data from The Lipogenic Regulator SREBP2 Induces Transferrin in Circulating Melanoma Cells and Suppresses Ferroptosis
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Hong, Xin, primary, Roh, Whijae, primary, Sullivan, Ryan J., primary, Wong, Keith H.K., primary, Wittner, Ben S., primary, Guo, Hongshan, primary, Dubash, Taronish D., primary, Sade-Feldman, Moshe, primary, Wesley, Benjamin, primary, Horwitz, Elad, primary, Boland, Genevieve M., primary, Marvin, Dieuwke L., primary, Bonesteel, Todd, primary, Lu, Chenyue, primary, Aguet, François, primary, Burr, Risa, primary, Freeman, Samuel S., primary, Parida, Laxmi, primary, Calhoun, Katherine, primary, Jewett, Michelle K., primary, Nieman, Linda T., primary, Hacohen, Nir, primary, Näär, Anders M., primary, Ting, David T., primary, Toner, Mehmet, primary, Stott, Shannon L., primary, Getz, Gad, primary, Maheswaran, Shyamala, primary, and Haber, Daniel A., primary
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- 2023
- Full Text
- View/download PDF
26. Supplementary Tables 1-8 from Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma
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Pectasides, Eirini, primary, Stachler, Matthew D., primary, Derks, Sarah, primary, Liu, Yang, primary, Maron, Steven, primary, Islam, Mirazul, primary, Alpert, Lindsay, primary, Kwak, Heewon, primary, Kindler, Hedy, primary, Polite, Blase, primary, Sharma, Manish R., primary, Allen, Kenisha, primary, O'Day, Emily, primary, Lomnicki, Samantha, primary, Maranto, Melissa, primary, Kanteti, Rajani, primary, Fitzpatrick, Carrie, primary, Weber, Christopher, primary, Setia, Namrata, primary, Xiao, Shu-Yuan, primary, Hart, John, primary, Nagy, Rebecca J., primary, Kim, Kyoung-Mee, primary, Choi, Min-Gew, primary, Min, Byung-Hoon, primary, Nason, Katie S., primary, O'Keefe, Lea, primary, Watanabe, Masayuki, primary, Baba, Hideo, primary, Lanman, Rick, primary, Agoston, Agoston T., primary, Oh, David J., primary, Dunford, Andrew, primary, Thorner, Aaron R., primary, Ducar, Matthew D., primary, Wollison, Bruce M., primary, Coleman, Haley A., primary, Ji, Yuan, primary, Posner, Mitchell C., primary, Roggin, Kevin, primary, Turaga, Kiran, primary, Chang, Paul, primary, Hogarth, Kyle, primary, Siddiqui, Uzma, primary, Gelrud, Andres, primary, Ha, Gavin, primary, Freeman, Samuel S., primary, Rhoades, Justin, primary, Reed, Sarah, primary, Gydush, Greg, primary, Rotem, Denisse, primary, Davison, Jon, primary, Imamura, Yu, primary, Adalsteinsson, Viktor, primary, Lee, Jeeyun, primary, Bass, Adam J., primary, and Catenacci, Daniel V., primary
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- 2023
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27. Supplementary Figure 4 from Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer
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Parsons, Heather A., primary, Rhoades, Justin, primary, Reed, Sarah C., primary, Gydush, Gregory, primary, Ram, Priyanka, primary, Exman, Pedro, primary, Xiong, Kan, primary, Lo, Christopher C., primary, Li, Tianyu, primary, Fleharty, Mark, primary, Kirkner, Gregory J., primary, Rotem, Denisse, primary, Cohen, Ofir, primary, Yu, Fangyan, primary, Fitarelli-Kiehl, Mariana, primary, Leong, Ka Wai, primary, Hughes, Melissa E., primary, Rosenberg, Shoshana M., primary, Collins, Laura C., primary, Miller, Kathy D., primary, Blumenstiel, Brendan, primary, Trippa, Lorenzo, primary, Cibulskis, Carrie, primary, Neuberg, Donna S., primary, DeFelice, Matthew, primary, Freeman, Samuel S., primary, Lennon, Niall J., primary, Wagle, Nikhil, primary, Ha, Gavin, primary, Stover, Daniel G., primary, Choudhury, Atish D., primary, Getz, Gad, primary, Winer, Eric P., primary, Meyerson, Matthew, primary, Lin, Nancy U., primary, Krop, Ian, primary, Love, J. Christopher, primary, Makrigiorgos, G. Mike, primary, Partridge, Ann H., primary, Mayer, Erica L., primary, Golub, Todd R., primary, and Adalsteinsson, Viktor A., primary
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- 2023
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28. Supplementary Data from Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer
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Parsons, Heather A., primary, Rhoades, Justin, primary, Reed, Sarah C., primary, Gydush, Gregory, primary, Ram, Priyanka, primary, Exman, Pedro, primary, Xiong, Kan, primary, Lo, Christopher C., primary, Li, Tianyu, primary, Fleharty, Mark, primary, Kirkner, Gregory J., primary, Rotem, Denisse, primary, Cohen, Ofir, primary, Yu, Fangyan, primary, Fitarelli-Kiehl, Mariana, primary, Leong, Ka Wai, primary, Hughes, Melissa E., primary, Rosenberg, Shoshana M., primary, Collins, Laura C., primary, Miller, Kathy D., primary, Blumenstiel, Brendan, primary, Trippa, Lorenzo, primary, Cibulskis, Carrie, primary, Neuberg, Donna S., primary, DeFelice, Matthew, primary, Freeman, Samuel S., primary, Lennon, Niall J., primary, Wagle, Nikhil, primary, Ha, Gavin, primary, Stover, Daniel G., primary, Choudhury, Atish D., primary, Getz, Gad, primary, Winer, Eric P., primary, Meyerson, Matthew, primary, Lin, Nancy U., primary, Krop, Ian, primary, Love, J. Christopher, primary, Makrigiorgos, G. Mike, primary, Partridge, Ann H., primary, Mayer, Erica L., primary, Golub, Todd R., primary, and Adalsteinsson, Viktor A., primary
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- 2023
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29. Supplementary Figure 1 from Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer
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Parsons, Heather A., primary, Rhoades, Justin, primary, Reed, Sarah C., primary, Gydush, Gregory, primary, Ram, Priyanka, primary, Exman, Pedro, primary, Xiong, Kan, primary, Lo, Christopher C., primary, Li, Tianyu, primary, Fleharty, Mark, primary, Kirkner, Gregory J., primary, Rotem, Denisse, primary, Cohen, Ofir, primary, Yu, Fangyan, primary, Fitarelli-Kiehl, Mariana, primary, Leong, Ka Wai, primary, Hughes, Melissa E., primary, Rosenberg, Shoshana M., primary, Collins, Laura C., primary, Miller, Kathy D., primary, Blumenstiel, Brendan, primary, Trippa, Lorenzo, primary, Cibulskis, Carrie, primary, Neuberg, Donna S., primary, DeFelice, Matthew, primary, Freeman, Samuel S., primary, Lennon, Niall J., primary, Wagle, Nikhil, primary, Ha, Gavin, primary, Stover, Daniel G., primary, Choudhury, Atish D., primary, Getz, Gad, primary, Winer, Eric P., primary, Meyerson, Matthew, primary, Lin, Nancy U., primary, Krop, Ian, primary, Love, J. Christopher, primary, Makrigiorgos, G. Mike, primary, Partridge, Ann H., primary, Mayer, Erica L., primary, Golub, Todd R., primary, and Adalsteinsson, Viktor A., primary
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- 2023
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30. Supplementary Figure 5 from Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer
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Parsons, Heather A., primary, Rhoades, Justin, primary, Reed, Sarah C., primary, Gydush, Gregory, primary, Ram, Priyanka, primary, Exman, Pedro, primary, Xiong, Kan, primary, Lo, Christopher C., primary, Li, Tianyu, primary, Fleharty, Mark, primary, Kirkner, Gregory J., primary, Rotem, Denisse, primary, Cohen, Ofir, primary, Yu, Fangyan, primary, Fitarelli-Kiehl, Mariana, primary, Leong, Ka Wai, primary, Hughes, Melissa E., primary, Rosenberg, Shoshana M., primary, Collins, Laura C., primary, Miller, Kathy D., primary, Blumenstiel, Brendan, primary, Trippa, Lorenzo, primary, Cibulskis, Carrie, primary, Neuberg, Donna S., primary, DeFelice, Matthew, primary, Freeman, Samuel S., primary, Lennon, Niall J., primary, Wagle, Nikhil, primary, Ha, Gavin, primary, Stover, Daniel G., primary, Choudhury, Atish D., primary, Getz, Gad, primary, Winer, Eric P., primary, Meyerson, Matthew, primary, Lin, Nancy U., primary, Krop, Ian, primary, Love, J. Christopher, primary, Makrigiorgos, G. Mike, primary, Partridge, Ann H., primary, Mayer, Erica L., primary, Golub, Todd R., primary, and Adalsteinsson, Viktor A., primary
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- 2023
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31. Supplementary Figure 8 from Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer
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Parsons, Heather A., primary, Rhoades, Justin, primary, Reed, Sarah C., primary, Gydush, Gregory, primary, Ram, Priyanka, primary, Exman, Pedro, primary, Xiong, Kan, primary, Lo, Christopher C., primary, Li, Tianyu, primary, Fleharty, Mark, primary, Kirkner, Gregory J., primary, Rotem, Denisse, primary, Cohen, Ofir, primary, Yu, Fangyan, primary, Fitarelli-Kiehl, Mariana, primary, Leong, Ka Wai, primary, Hughes, Melissa E., primary, Rosenberg, Shoshana M., primary, Collins, Laura C., primary, Miller, Kathy D., primary, Blumenstiel, Brendan, primary, Trippa, Lorenzo, primary, Cibulskis, Carrie, primary, Neuberg, Donna S., primary, DeFelice, Matthew, primary, Freeman, Samuel S., primary, Lennon, Niall J., primary, Wagle, Nikhil, primary, Ha, Gavin, primary, Stover, Daniel G., primary, Choudhury, Atish D., primary, Getz, Gad, primary, Winer, Eric P., primary, Meyerson, Matthew, primary, Lin, Nancy U., primary, Krop, Ian, primary, Love, J. Christopher, primary, Makrigiorgos, G. Mike, primary, Partridge, Ann H., primary, Mayer, Erica L., primary, Golub, Todd R., primary, and Adalsteinsson, Viktor A., primary
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- 2023
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32. Supplementary Figure 3 from Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer
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Parsons, Heather A., primary, Rhoades, Justin, primary, Reed, Sarah C., primary, Gydush, Gregory, primary, Ram, Priyanka, primary, Exman, Pedro, primary, Xiong, Kan, primary, Lo, Christopher C., primary, Li, Tianyu, primary, Fleharty, Mark, primary, Kirkner, Gregory J., primary, Rotem, Denisse, primary, Cohen, Ofir, primary, Yu, Fangyan, primary, Fitarelli-Kiehl, Mariana, primary, Leong, Ka Wai, primary, Hughes, Melissa E., primary, Rosenberg, Shoshana M., primary, Collins, Laura C., primary, Miller, Kathy D., primary, Blumenstiel, Brendan, primary, Trippa, Lorenzo, primary, Cibulskis, Carrie, primary, Neuberg, Donna S., primary, DeFelice, Matthew, primary, Freeman, Samuel S., primary, Lennon, Niall J., primary, Wagle, Nikhil, primary, Ha, Gavin, primary, Stover, Daniel G., primary, Choudhury, Atish D., primary, Getz, Gad, primary, Winer, Eric P., primary, Meyerson, Matthew, primary, Lin, Nancy U., primary, Krop, Ian, primary, Love, J. Christopher, primary, Makrigiorgos, G. Mike, primary, Partridge, Ann H., primary, Mayer, Erica L., primary, Golub, Todd R., primary, and Adalsteinsson, Viktor A., primary
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- 2023
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33. Supplementary Figure 9 from Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer
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Parsons, Heather A., primary, Rhoades, Justin, primary, Reed, Sarah C., primary, Gydush, Gregory, primary, Ram, Priyanka, primary, Exman, Pedro, primary, Xiong, Kan, primary, Lo, Christopher C., primary, Li, Tianyu, primary, Fleharty, Mark, primary, Kirkner, Gregory J., primary, Rotem, Denisse, primary, Cohen, Ofir, primary, Yu, Fangyan, primary, Fitarelli-Kiehl, Mariana, primary, Leong, Ka Wai, primary, Hughes, Melissa E., primary, Rosenberg, Shoshana M., primary, Collins, Laura C., primary, Miller, Kathy D., primary, Blumenstiel, Brendan, primary, Trippa, Lorenzo, primary, Cibulskis, Carrie, primary, Neuberg, Donna S., primary, DeFelice, Matthew, primary, Freeman, Samuel S., primary, Lennon, Niall J., primary, Wagle, Nikhil, primary, Ha, Gavin, primary, Stover, Daniel G., primary, Choudhury, Atish D., primary, Getz, Gad, primary, Winer, Eric P., primary, Meyerson, Matthew, primary, Lin, Nancy U., primary, Krop, Ian, primary, Love, J. Christopher, primary, Makrigiorgos, G. Mike, primary, Partridge, Ann H., primary, Mayer, Erica L., primary, Golub, Todd R., primary, and Adalsteinsson, Viktor A., primary
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- 2023
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34. Supplementary Figure 7 from Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer
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Parsons, Heather A., primary, Rhoades, Justin, primary, Reed, Sarah C., primary, Gydush, Gregory, primary, Ram, Priyanka, primary, Exman, Pedro, primary, Xiong, Kan, primary, Lo, Christopher C., primary, Li, Tianyu, primary, Fleharty, Mark, primary, Kirkner, Gregory J., primary, Rotem, Denisse, primary, Cohen, Ofir, primary, Yu, Fangyan, primary, Fitarelli-Kiehl, Mariana, primary, Leong, Ka Wai, primary, Hughes, Melissa E., primary, Rosenberg, Shoshana M., primary, Collins, Laura C., primary, Miller, Kathy D., primary, Blumenstiel, Brendan, primary, Trippa, Lorenzo, primary, Cibulskis, Carrie, primary, Neuberg, Donna S., primary, DeFelice, Matthew, primary, Freeman, Samuel S., primary, Lennon, Niall J., primary, Wagle, Nikhil, primary, Ha, Gavin, primary, Stover, Daniel G., primary, Choudhury, Atish D., primary, Getz, Gad, primary, Winer, Eric P., primary, Meyerson, Matthew, primary, Lin, Nancy U., primary, Krop, Ian, primary, Love, J. Christopher, primary, Makrigiorgos, G. Mike, primary, Partridge, Ann H., primary, Mayer, Erica L., primary, Golub, Todd R., primary, and Adalsteinsson, Viktor A., primary
- Published
- 2023
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35. Supplementary Figure 6 from Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer
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Parsons, Heather A., primary, Rhoades, Justin, primary, Reed, Sarah C., primary, Gydush, Gregory, primary, Ram, Priyanka, primary, Exman, Pedro, primary, Xiong, Kan, primary, Lo, Christopher C., primary, Li, Tianyu, primary, Fleharty, Mark, primary, Kirkner, Gregory J., primary, Rotem, Denisse, primary, Cohen, Ofir, primary, Yu, Fangyan, primary, Fitarelli-Kiehl, Mariana, primary, Leong, Ka Wai, primary, Hughes, Melissa E., primary, Rosenberg, Shoshana M., primary, Collins, Laura C., primary, Miller, Kathy D., primary, Blumenstiel, Brendan, primary, Trippa, Lorenzo, primary, Cibulskis, Carrie, primary, Neuberg, Donna S., primary, DeFelice, Matthew, primary, Freeman, Samuel S., primary, Lennon, Niall J., primary, Wagle, Nikhil, primary, Ha, Gavin, primary, Stover, Daniel G., primary, Choudhury, Atish D., primary, Getz, Gad, primary, Winer, Eric P., primary, Meyerson, Matthew, primary, Lin, Nancy U., primary, Krop, Ian, primary, Love, J. Christopher, primary, Makrigiorgos, G. Mike, primary, Partridge, Ann H., primary, Mayer, Erica L., primary, Golub, Todd R., primary, and Adalsteinsson, Viktor A., primary
- Published
- 2023
- Full Text
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36. Supplementary Tables from Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer
- Author
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Parsons, Heather A., primary, Rhoades, Justin, primary, Reed, Sarah C., primary, Gydush, Gregory, primary, Ram, Priyanka, primary, Exman, Pedro, primary, Xiong, Kan, primary, Lo, Christopher C., primary, Li, Tianyu, primary, Fleharty, Mark, primary, Kirkner, Gregory J., primary, Rotem, Denisse, primary, Cohen, Ofir, primary, Yu, Fangyan, primary, Fitarelli-Kiehl, Mariana, primary, Leong, Ka Wai, primary, Hughes, Melissa E., primary, Rosenberg, Shoshana M., primary, Collins, Laura C., primary, Miller, Kathy D., primary, Blumenstiel, Brendan, primary, Trippa, Lorenzo, primary, Cibulskis, Carrie, primary, Neuberg, Donna S., primary, DeFelice, Matthew, primary, Freeman, Samuel S., primary, Lennon, Niall J., primary, Wagle, Nikhil, primary, Ha, Gavin, primary, Stover, Daniel G., primary, Choudhury, Atish D., primary, Getz, Gad, primary, Winer, Eric P., primary, Meyerson, Matthew, primary, Lin, Nancy U., primary, Krop, Ian, primary, Love, J. Christopher, primary, Makrigiorgos, G. Mike, primary, Partridge, Ann H., primary, Mayer, Erica L., primary, Golub, Todd R., primary, and Adalsteinsson, Viktor A., primary
- Published
- 2023
- Full Text
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37. Supplementary Figure 2 from Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer
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Parsons, Heather A., primary, Rhoades, Justin, primary, Reed, Sarah C., primary, Gydush, Gregory, primary, Ram, Priyanka, primary, Exman, Pedro, primary, Xiong, Kan, primary, Lo, Christopher C., primary, Li, Tianyu, primary, Fleharty, Mark, primary, Kirkner, Gregory J., primary, Rotem, Denisse, primary, Cohen, Ofir, primary, Yu, Fangyan, primary, Fitarelli-Kiehl, Mariana, primary, Leong, Ka Wai, primary, Hughes, Melissa E., primary, Rosenberg, Shoshana M., primary, Collins, Laura C., primary, Miller, Kathy D., primary, Blumenstiel, Brendan, primary, Trippa, Lorenzo, primary, Cibulskis, Carrie, primary, Neuberg, Donna S., primary, DeFelice, Matthew, primary, Freeman, Samuel S., primary, Lennon, Niall J., primary, Wagle, Nikhil, primary, Ha, Gavin, primary, Stover, Daniel G., primary, Choudhury, Atish D., primary, Getz, Gad, primary, Winer, Eric P., primary, Meyerson, Matthew, primary, Lin, Nancy U., primary, Krop, Ian, primary, Love, J. Christopher, primary, Makrigiorgos, G. Mike, primary, Partridge, Ann H., primary, Mayer, Erica L., primary, Golub, Todd R., primary, and Adalsteinsson, Viktor A., primary
- Published
- 2023
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38. Protocol for bulk RNA sequencing of enriched human neutrophils from whole blood and estimation of sample purity
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Gonye, Anna L.K., primary, LaSalle, Thomas J., additional, Freeman, Samuel S., additional, Reyes, Miguel, additional, Hacohen, Nir, additional, Villani, Alexandra-Chloé, additional, and Sade-Feldman, Moshe, additional
- Published
- 2023
- Full Text
- View/download PDF
39. Characterization of HPV and host genome interactions in primary head and neck cancers
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Cancer Genome Atlas Network, Parfenov, Michael, Pedamallu, Chandra Sekhar, Gehlenborg, Nils, Freeman, Samuel S., Danilova, Ludmila, Bristow, Christopher A., Lee, Semin, Hadjipanayis, Angela G., Ivanova, Elena V., Wilkerson, Matthew D., Protopopov, Alexei, Yang, Lixing, Seth, Sahil, Song, Xingzhi, Tang, Jiabin, Ren, Xiaojia, Zhang, Jianhua, Pantazi, Angeliki, Santoso, Netty, Xu, Andrew W., Mahadeshwar, Harshad, Wheeler, David A., Haddad, Robert I., Jung, Joonil, Ojesina, Akinyemi I., Issaeva, Natalia, Yarbrough, Wendell G., Hayes, D. Neil, Grandis, Jennifer R., K. El-Naggar, Adel, Meyerson, Matthew, Park, Peter J., Chin, Lynda, Seidman, J. G., Hammerman, Peter S., and Kucherlapati, Raju
- Published
- 2014
40. Longitudinal characterization of circulating neutrophils uncovers phenotypes associated with severity in hospitalized COVID-19 patients
- Author
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LaSalle, Thomas J., primary, Gonye, Anna L.K., additional, Freeman, Samuel S., additional, Kaplonek, Paulina, additional, Gushterova, Irena, additional, Kays, Kyle R., additional, Manakongtreecheep, Kasidet, additional, Tantivit, Jessica, additional, Rojas-Lopez, Maricarmen, additional, Russo, Brian C., additional, Sharma, Nihaarika, additional, Thomas, Molly F., additional, Lavin-Parsons, Kendall M., additional, Lilly, Brendan M., additional, Mckaig, Brenna N., additional, Charland, Nicole C., additional, Khanna, Hargun K., additional, Lodenstein, Carl L., additional, Margolin, Justin D., additional, Blaum, Emily M., additional, Lirofonis, Paola B., additional, Revach, Or-Yam, additional, Mehta, Arnav, additional, Sonny, Abraham, additional, Bhattacharyya, Roby P., additional, Parry, Blair Alden, additional, Goldberg, Marcia B., additional, Alter, Galit, additional, Filbin, Michael R., additional, Villani, Alexandra-Chloé, additional, Hacohen, Nir, additional, and Sade-Feldman, Moshe, additional
- Published
- 2022
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41. Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing
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Koch Institute for Integrative Cancer Research at MIT, Viswanathan, Srinivas R., Ha, Gavin, Hoff, Andreas M., Wala, Jeremiah A., Carrot-Zhang, Jian, Whelan, Christopher W., Haradhvala, Nicholas J., Freeman, Samuel S., Reed, Sarah C., Rhoades, Justin, Polak, Paz, Cipicchio, Michelle, Wankowicz, Stephanie A., Wong, Alicia, Kamath, Tushar, Zhang, Zhenwei, Gydush, Gregory J., Rotem, Denisse, Love, J. Christopher, Getz, Gad, Gabriel, Stacey, Zhang, Cheng-Zhong, Dehm, Scott M., Nelson, Peter S., Van Allen, Eliezer M., Choudhury, Atish D., Adalsteinsson, Viktor A., Beroukhim, Rameen, Taplin, Mary-Ellen, Meyerson, Matthew, Koch Institute for Integrative Cancer Research at MIT, Viswanathan, Srinivas R., Ha, Gavin, Hoff, Andreas M., Wala, Jeremiah A., Carrot-Zhang, Jian, Whelan, Christopher W., Haradhvala, Nicholas J., Freeman, Samuel S., Reed, Sarah C., Rhoades, Justin, Polak, Paz, Cipicchio, Michelle, Wankowicz, Stephanie A., Wong, Alicia, Kamath, Tushar, Zhang, Zhenwei, Gydush, Gregory J., Rotem, Denisse, Love, J. Christopher, Getz, Gad, Gabriel, Stacey, Zhang, Cheng-Zhong, Dehm, Scott M., Nelson, Peter S., Van Allen, Eliezer M., Choudhury, Atish D., Adalsteinsson, Viktor A., Beroukhim, Rameen, Taplin, Mary-Ellen, and Meyerson, Matthew
- Abstract
© 2018 Elsevier Inc. Nearly all prostate cancer deaths are from metastatic castration-resistant prostate cancer (mCRPC), but there have been few whole-genome sequencing (WGS) studies of this disease state. We performed linked-read WGS on 23 mCRPC biopsy specimens and analyzed cell-free DNA sequencing data from 86 patients with mCRPC. In addition to frequent rearrangements affecting known prostate cancer genes, we observed complex rearrangements of the AR locus in most cases. Unexpectedly, these rearrangements include highly recurrent tandem duplications involving an upstream enhancer of AR in 70%–87% of cases compared with <2% of primary prostate cancers. A subset of cases displayed AR or MYC enhancer duplication in the context of a genome-wide tandem duplicator phenotype associated with CDK12 inactivation. Our findings highlight the complex genomic structure of mCRPC, nominate alterations that may inform prostate cancer treatment, and suggest that additional recurrent events in the non-coding mCRPC genome remain to be discovered. Linked-read genome sequencing data from patients highlight that amplification of an enhancer upstream of the androgen receptor locus is a key feature of metastatic castration-resistant prostate cancer.
- Published
- 2022
42. Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer
- Author
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Parsons, Heather A., Rhoades, Justin, Reed, Sarah C., Gydush, Gregory, Ram, Priyanka, Exman, Pedro, Xiong, Kan, Lo, Christopher C., Li, Tianyu, Fleharty, Mark, Kirkner, Gregory J., Rotem, Denisse, Cohen, Ofir, Yu, Fangyan, Fitarelli-Kiehl, Mariana, Leong, Ka Wai, Hughes, Melissa E., Rosenberg, Shoshana M., Collins, Laura C., Miller, Kathy D., Blumenstiel, Brendan, Trippa, Lorenzo, Cibulskis, Carrie, Neuberg, Donna S., DeFelice, Matthew, Freeman, Samuel S., Lennon, Niall J., Wagle, Nikhil, Ha, Gavin, Stover, Daniel G., Choudhury, Atish D., Getz, Gad, Winer, Eric P., Meyerson, Matthew, Lin, Nancy U., Krop, Ian, Love, J. Christopher, Makrigiorgos, G. Mike, Partridge, Ann H., Mayer, Erica L., Golub, Todd R., Adalsteinsson, Viktor A., Parsons, Heather A., Rhoades, Justin, Reed, Sarah C., Gydush, Gregory, Ram, Priyanka, Exman, Pedro, Xiong, Kan, Lo, Christopher C., Li, Tianyu, Fleharty, Mark, Kirkner, Gregory J., Rotem, Denisse, Cohen, Ofir, Yu, Fangyan, Fitarelli-Kiehl, Mariana, Leong, Ka Wai, Hughes, Melissa E., Rosenberg, Shoshana M., Collins, Laura C., Miller, Kathy D., Blumenstiel, Brendan, Trippa, Lorenzo, Cibulskis, Carrie, Neuberg, Donna S., DeFelice, Matthew, Freeman, Samuel S., Lennon, Niall J., Wagle, Nikhil, Ha, Gavin, Stover, Daniel G., Choudhury, Atish D., Getz, Gad, Winer, Eric P., Meyerson, Matthew, Lin, Nancy U., Krop, Ian, Love, J. Christopher, Makrigiorgos, G. Mike, Partridge, Ann H., Mayer, Erica L., Golub, Todd R., and Adalsteinsson, Viktor A.
- Abstract
© 2020 American Association for Cancer Research. Purpose: Existing cell-free DNA (cfDNA) methods lack the sensitivity needed for detecting minimal residual disease (MRD) following therapy. We developed a test for tracking hundreds of patient-specific mutations to detect MRD with a 1,000-fold lower error rate than conventional sequencing. Experimental Design: We compared the sensitivity of our approach to digital droplet PCR (ddPCR) in a dilution series, then retrospectively identified two cohorts of patients who had undergone prospective plasma sampling and clinical data collection: 16 patients with ER+/HER2- metastatic breast cancer (MBC) sampled within 6 months following metastatic diagnosis and 142 patients with stage 0 to III breast cancer who received curative-intent treatment with most sampled at surgery and 1 year postoperative. We performed whole-exome sequencing of tumors and designed individualized MRD tests, which we applied to serial cfDNA samples. Results: Our approach was 100-fold more sensitive than ddPCR when tracking 488 mutations, but most patients had fewer identifiable tumor mutations to track in cfDNA (median = 57; range = 2–346). Clinical sensitivity was 81% (n = 13/16) in newly diagnosed MBC, 23% (n = 7/30) at postoperative and 19% (n = 6/32) at 1 year in early-stage disease, and highest in patients with the most tumor mutations available to track. MRD detection at 1 year was strongly associated with distant recurrence [HR = 20.8; 95% confidence interval, 7.3–58.9]. Median lead time from first positive sample to recurrence was 18.9 months (range = 3.4–39.2 months). Conclusions: Tracking large numbers of individualized tumor mutations in cfDNA can improve MRD detection, but its sensitivity is driven by the number of tumor mutations available to track.
- Published
- 2022
43. Abstract 3610: In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancer
- Author
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Dubrot, Juan, primary, Du, Peter P., additional, Lane-Reticker, Sarah Kate, additional, Kessler, Emily A., additional, Muscato, Audrey J., additional, Mehta, Arnav, additional, Freeman, Samuel S., additional, Allen, Peter M., additional, Olander, Kira E., additional, Ockerman, Kyle M., additional, Wolfe, Clara H., additional, Wiesmann, Fabius, additional, Knudsen, Nelson H., additional, Tsao, Hsiao-Wei, additional, Iracheta-Vellve, Arvin, additional, Schneider, Emily M., additional, Rivera-Rosario, Andrea N., additional, Kohnle, Ian C., additional, Pope, Hans W., additional, Ayer, Austin, additional, Mishra, Gargi, additional, Zimmer, Margaret D., additional, Kim, Sarah Y., additional, Mahapatra, Animesh, additional, Ebrahimi-Nik, Hakimeh, additional, Frederick, Dennie T., additional, Boland, Genevieve M., additional, Haining, W. Nicholas, additional, Root, David E., additional, Doench, John G., additional, Hacohen, Nir, additional, Yates, Kathleen B., additional, and Manguso, Robert T., additional
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- 2022
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44. Abstract 2259: Predictive modeling of smoldering multiple myeloma progression to multiple myeloma by continuous variable analysis
- Author
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Cowan, Annie, primary, El-Khoury, Habib, additional, Ferrari, Federico, additional, Freeman, Samuel S., additional, Redd, Robert, additional, Perry, Jacqueline, additional, Patel, Vidhi, additional, Kaur, Priya, additional, Barr, Hadley, additional, Downey, Katelyn, additional, Argyelan, David, additional, Justis, Anna V., additional, Lee, David J., additional, Lightbody, Elizabeth D., additional, Theodorakakou, Foteini, additional, Fotiou, Despina, additional, Kanellias, Nikolaos, additional, Liacos, Christine, additional, Getz, Gad, additional, Trippa, Lorenzo, additional, Marinac, Catherine, additional, Kastritis, Efstathios, additional, Meletios, Dimopoulos, additional, and Ghobrial, Irene, additional
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- 2022
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45. GeneVector: Identification of transcriptional programs using dense vector representations defined by mutual information
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Ceglia, Nicholas, primary, Sethna, Zachary, additional, Freeman, Samuel S., additional, Uhlitz, Florian, additional, Bojilova, Viktoria, additional, Rusk, Nicole, additional, Burman, Bharat, additional, Chow, Andrew, additional, Salehi, Sohrab, additional, Kabeer, Farhia, additional, Aparicio, Samuel, additional, Greenbaum, Benjamin, additional, Shah, Sohrab P., additional, and McPherson, Andrew, additional
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- 2022
- Full Text
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46. Integrative Analysis of Checkpoint Blockade Response in Advanced Non-Small Cell Lung Cancer
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Ravi, Arvind, primary, Gainor, Justin F, additional, Arniella, Monica B, additional, Holton, Mark, additional, Freeman, Samuel S, additional, Stewart, Chip, additional, Leshchiner, Ignaty, additional, Kim, Jaegil, additional, Akiyama, Yo, additional, Griffin, Aaron T, additional, Vokes, Natalie I, additional, Sakhi, Mustafa, additional, Kamesan, Vashine, additional, Rizvi, Hira, additional, Ricciuti, Biagio, additional, Forde, Patrick M, additional, Anagnostou, Valsamo, additional, Reiss, Jonathan W, additional, Gibbons, Don L, additional, Pennell, Nathan A, additional, Velcheti, Vamsidhar, additional, Digumarthy, Subbha R, additional, Mino-Kenudson, Mari, additional, Califano, Andrea, additional, Heymach, John V, additional, Herbst, Roy S, additional, Brahmer, Julie R, additional, Schalper, Kurt A, additional, Velculescu, Victor E, additional, Henick, Brian S, additional, Rizvi, Naiyer, additional, Janne, Pasi A, additional, Awad, Mark M, additional, Chow, Andrew, additional, Greenbaum, Benjamin D, additional, Luksza, Marta, additional, Shaw, Alice T, additional, Wolchok, Jedd, additional, Hacohen, Nir, additional, Getz, Gad, additional, and Hellmann, Matthew D, additional
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- 2022
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47. Combined tumor and immune signals from genomes or transcriptomes predict outcomes of checkpoint inhibition in melanoma
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Freeman, Samuel S., primary, Sade-Feldman, Moshe, additional, Kim, Jaegil, additional, Stewart, Chip, additional, Gonye, Anna L.K., additional, Ravi, Arvind, additional, Arniella, Monica B., additional, Gushterova, Irena, additional, LaSalle, Thomas J., additional, Blaum, Emily M., additional, Yizhak, Keren, additional, Frederick, Dennie T., additional, Sharova, Tatyana, additional, Leshchiner, Ignaty, additional, Elagina, Liudmila, additional, Spiro, Oliver G., additional, Livitz, Dimitri, additional, Rosebrock, Daniel, additional, Aguet, François, additional, Carrot-Zhang, Jian, additional, Ha, Gavin, additional, Lin, Ziao, additional, Chen, Jonathan H., additional, Barzily-Rokni, Michal, additional, Hammond, Marc R., additional, Vitzthum von Eckstaedt, Hans C., additional, Blackmon, Shauna M., additional, Jiao, Yunxin J., additional, Gabriel, Stacey, additional, Lawrence, Donald P., additional, Duncan, Lyn M., additional, Stemmer-Rachamimov, Anat O., additional, Wargo, Jennifer A., additional, Flaherty, Keith T., additional, Sullivan, Ryan J., additional, Boland, Genevieve M., additional, Meyerson, Matthew, additional, Getz, Gad, additional, and Hacohen, Nir, additional
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- 2022
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48. Implementation of a prostate cancer‐specific targeted sequencing panel for credentialing of patient‐derived cell lines and genomic characterization of patient samples
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Stover, Elizabeth H., primary, Oh, Coyin, additional, Keskula, Paula, additional, Choudhury, Atish D., additional, Tseng, Yuen‐Yi, additional, Adalsteinsson, Viktor A., additional, Lohr, Jens G., additional, Thorner, Aaron R., additional, Ducar, Matthew, additional, Kryukov, Gregory V., additional, Ha, Gavin, additional, Rosenberg, Mara, additional, Freeman, Samuel S., additional, Zhang, Zhenwei, additional, Wu, Xiaoyun, additional, Van Allen, Eliezer M., additional, Takeda, David Y., additional, Loda, Massimo, additional, Wu, Chin‐Lee, additional, Taplin, Mary‐Ellen, additional, Garraway, Levi A., additional, Boehm, Jesse S., additional, and Huang, Franklin W., additional
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- 2022
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49. Genomic aberrations in cervical adenocarcinomas in Hong Kong Chinese women
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Chung, Tony K.H., Van Hummelen, Paul, Chan, Paul K.S., Cheung, Tak Hong, Yim, So Fan, Yu, Mei Y., Ducar, Matthew D., Thorner, Aaron R., MacConaill, Laura E., Doran, Graeme, Pedamallu, Chandra Sekhar, Ojesina, Akinyemi I., Wong, Raymond R.Y., Wang, Vivian W., Freeman, Samuel S., Lau, Tat San, Kwong, Joseph, Chan, Loucia K.Y., Fromer, Menachem, May, Taymaa, Worley, Michael J., Jr., Esselen, Katharine M., Elias, Kevin M., Lawrence, Michael, Getz, Gad, Smith, David I., Crum, Christopher P., Meyerson, Matthew, Berkowitz, Ross S., and Wong, Yick Fu
- Published
- 2015
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50. Longitudinal characterization of circulating neutrophils uncovers distinct phenotypes associated with disease severity in hospitalized COVID-19 patients
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LaSalle, Thomas J., primary, Gonye, Anna L. K., additional, Freeman, Samuel S., additional, Kaplonek, Paulina, additional, Gushterova, Irena, additional, Kays, Kyle R., additional, Manakongtreecheep, Kasidet, additional, Tantivit, Jessica, additional, Rojas-Lopez, Maricarmen, additional, Russo, Brian C., additional, Sharma, Nihaarika, additional, Thomas, Molly F., additional, Lavin-Parsons, Kendall M., additional, Lilly, Brendan M., additional, Mckaig, Brenna N., additional, Charland, Nicole C., additional, Khanna, Hargun K., additional, Lodenstein, Carl L., additional, Margolin, Justin D., additional, Blaum, Emily M., additional, Lirofonis, Paola B., additional, Sonny, Abraham, additional, Bhattacharyya, Roby P., additional, Parry, Blair Alden, additional, Goldberg, Marcia B., additional, Alter, Galit, additional, Filbin, Michael R., additional, Villani, Alexandra Chloe, additional, Hacohen, Nir, additional, and Sade-Feldman, Moshe, additional
- Published
- 2021
- Full Text
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