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Objective: This study tested the hypothesis that expression of insulin-like growth factor 1 (IGF-1) protein and mRNA splice variants is lower in skeletal muscle of humans with obesity who have a lower mixed-muscle protein fractional synthesis rate (MMP-FSR) when compared with individuals without obesity., Methods: The study included nine participants with obesity (OB, mean [SD],  BMI = 35 [3] kg/m 2 , MMP-FSR = 0.06%/h [0.02%/h]) and nine participants without obesity (W-OB, BMI = 24 [3] kg/m 2 , MMP-FSR = 0.08%/h [0.02%/h]; for both BMI and MMP-FSR p < 0.05). MMP-FSR and mitochondrial protein FSR were measured following an overnight fast., Results: Along with lower MMP-FSR, OB participants displayed lower mitochondrial protein FSR (p = 0.03) compared with W-OB participants. Expression of IGF-1 (p = 0.04) and IGF-1 receptor (p < 0.01) proteins was lower in muscle of OB participants. In addition, OB participants had lower (p < 0.05) mRNA expression of IGF1 variants Eb and Ec. This study demonstrates that lower protein synthesis in muscle of humans with obesity occurs concurrently with lower expression of muscle IGF-1 and IGF-1 receptor proteins, as well as lower mRNA expression of the IGF1 splice variants., Conclusions: These findings indicate that lower protein synthesis observed in muscle of humans with obesity may result from diminished muscle IGF1 gene expression., (© 2023 The Obesity Society.)

We compared the effects of aerobic exercise with and without blood flow restriction (BFR) to high-intensity aerobic exercise on energy expenditure (EE), excess Postexercise oxygen consumption (EPOC), and respiratory exchange ratio (RER) during and after exercise. Twenty-two recreationally active males randomly completed the following experimental conditions: AE-aerobic exercise without BFR, AE + BFR-aerobic exercise with BFR, HIAE-high-intensity aerobic exercise, CON-non-exercise control condition. EE was significantly (p < 0.05) greater during exercise for HIAE compared to all conditions, and for AE + BFR compared to AE and CON during and postexercise exercise. There were no significant (p > 0.05) differences in EPOC between HIAE and AE + BFR at any time point, however, both conditions were significantly (p < 0.05) greater than the AE (d = 1.50 and d = 1.03, respectively) and CON at the first 10 min postexercise. RER during exercise for HIAE was significantly (p < 0.05) greater than AE + BFR at the first 6 min of exercise (p = 0.003, d = 0.88), however, no significant differences were observed from 9 min up to the end of the exercise. HIAE was also significantly (p < 0.05) greater than AE and CON at all time points during exercise, whereas, AE + BFR was significantly (p < 0.05) greater than CON at all time points but not significantly (p < 0.05) different than AE (p < 0.05); although the overall session RER was significantly (p < 0.05) greater during AE + BFR than AE. Altogether, continuous AE + BFR results in greater EE compared to volume matched AE, as well as a similar EPOC compared to HIAE., (© 2022 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.)

Studies investigating the proteome of skeletal muscle present clear evidence that protein metabolism is altered in muscle of humans with obesity. Moreover, muscle quality (i.e., strength per unit of muscle mass) appears lower in humans with obesity. However, relevant evidence to date describing the protein turnover, a process that determines content and quality of protein, in muscle of humans with obesity is quite inconsistent. This is due, at least in part, to heterogeneity in protein turnover in skeletal muscle of humans with obesity. Although not always evident at the mixed-muscle protein level, the rate of synthesis is generally lower in myofibrillar and mitochondrial proteins in muscle of humans with obesity. Moreover, alterations in the synthesis of protein in muscle of humans with obesity are manifested more readily under conditions that stimulate protein synthesis in muscle, including the fed state, increased plasma amino acid availability to muscle, and exercise. Current evidence supports various biological mechanisms explaining impairments in protein synthesis in muscle of humans with obesity, but this evidence is rather limited and needs to be reproduced under more defined experimental conditions. Expanding our current knowledge with direct measurements of protein breakdown in muscle, and more importantly of protein turnover on a protein by protein basis, will enhance our understanding of how obesity modifies the proteome (content and quality) in muscle of humans with obesity., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 Freitas and Katsanos.)

This cross-sectional study examined the associations between serum interleukin-6 (IL-6) and muscle, bone, and fat parameters in recreationally active women. One-hundred forty-five women (48.7 ± 17.8 years; 164.4 ± 7.1 cm; 66.8 ± 10.7 kg; and 24.7 ± 3.9 kg/m 2 ) underwent dual energy x-ray absorptiometry (DXA) and peripheral quantitative computed tomography (pQCT) assessments to determine total and regional muscle, bone, and fat parameters. Muscle performance of the knee extensors was examined via isometric, isotonic, and isokinetic dynamometry assessments, and serum IL-6 was measured via enzyme linked immunosorbent assay. Serum IL-6 was inversely associated with thigh muscle cross-sectional area (mCSA, r = -0.28, p < 0.01); isometric strength (r = -0.19, p < 0.05); hip areal bone mineral density [aBMD] (r = -0.18, p < 0.05); trochanter aBMD (r = -0.23, p < 0.01); total body aBMD (r = -0.20, p < 0.05); cortical volumetric bone density at 38 and 66% tibia (r = -0.18 and r = -0.19, respectively, both p < 0.05), and 66% cortical thickness (r = -0.17, p < 0.05). These associations were present after adjusting for age, BMI, and physical activity. Thigh mCSA was significantly lower in the tertile possessing the greatest IL-6 compared to the lowest tertile (p < 0.01); after adjusting for age, body mass index, and physical activity. Collectively, these observations indicate that IL-6 is inversely associated with skeletal muscle and bone parameters independent of relevant confounders. These observations bolster the prognostic value of serum IL-6., (Copyright © 2021. Published by Elsevier Ltd.)

The use of blood flow restricted (BFR) exercise has become an accepted alternative approach to improve skeletal muscle mass and function and improve cardiovascular function in individuals that are not able to or do not wish to use traditional exercise protocols that rely on heavy loads and high training volumes. BFR exercise involves the reduction of blood flow to working skeletal muscle by applying a flexible cuff to the most proximal portions of a person's arms or legs that results in decreased arterial flow to the exercising muscle and occluded venous return back to the central circulation. Safety concerns, especially related to the cardiovascular system, have not been consistently reported with a few exceptions; however, most researchers agree that BFR exercise can be a relatively safe technique for most people that are free from serious cardiovascular disease, as well as those with coronary artery disease, and also for people suffering from chronic conditions, such as multiple sclerosis, Parkinson's, and osteoarthritis. Potential mechanisms to explain the benefits of BFR exercise are still mostly speculative and may require more invasive studies or the use of animal models to fully explore mechanisms of adaptation. The setting of absolute resistive pressures has evolved, from being based on an individual's systolic blood pressure to a relative measure that is based on various percentages of the pressures needed to totally occlude blood flow in the exercising limb. However, since several other issues remain unresolved, such as the actual external loads used in combination with BFR, the type of cuff used to induce the blood flow restriction, and whether the restriction is continuous or intermittent, this paper will attempt to address these additional concerns., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2021 Freitas, Karabulut and Bemben.)

Abstract: Ferreira-Júnior, JB, Benine, RPC, Chaves, SFN, Borba, DA, Martins-Costa, HC, Freitas, EDS, Bemben, MG, Vieira, CA, and Bottaro, M. Effects of static and dynamic stretching performed before resistance training on muscle adaptations in untrained men. J Strength Cond Res 35(11): 3050-3055, 2021-This study evaluated the effects of dynamic and static stretching (SS) performed before resistance training on biceps femoris hypertrophy and knee flexor strength gains in untrained young men. Forty-five untrained young men (age, 21.2 ± 0.5 years; mass, 72.2 ± 5.6 kg; height, 178 ± 1 cm) were randomly assigned to 1 of the 3 groups: (a) 80 seconds of SS (n = 14); (b) 80 seconds of dynamic stretching (DS, n = 13); or (c) control group (CON, n = 18) in which subjects performed no stretching before exercise. Both SS and DS were performed before resistance exercise. Resistance training consisted of 4 sets of 8-12 repetition maximum of seated leg curl exercise 2 days per week for 8 weeks, with a period of at least 48 hours between sessions. Unilateral biceps femoris muscle thickness (MT) and maximal isometric strength (MIS) of the knee flexors were measured 1 week before training and 1 week after the last training session. There were significant increases in MIS (SS = 13.9 ± 10.3 kgf; DS = 10.2 ± 13.1 kgf; CON = 12.7 ± 7.6 kgf; p < 0.05) and MT (SS = 6.0 ± 3.5 mm; DS = 6.7 ± 4.1 mm; CON = 5.7 ± 3.0 mm; p < 0.05) with no significant differences across groups (p > 0.05). Additionally, all groups demonstrated moderate effect sizes for MIS (1.27-1.4), and DS was the only group that had a large effect size for MT increases (DS = 2.18; SS = 1.35; CON = 0.92). In conclusion, 80 seconds of SS and DS did not induce any additional muscular adaptations to resistance training in untrained young men., (Copyright © 2019 National Strength and Conditioning Association.)

Abstract: Silva, JCG, Domingos-Gomes, JR, Freitas, EDS, Neto, GR, Aniceto, RR, Bemben, MG, Lima-dos-Santos, A, and Cirilo-Sousa, MS. Physiological and perceptual responses to aerobic exercise with and without blood flow restriction. J Strength Cond Res 35(9): 2479-2485, 2021-Although previous studies have demonstrated the potential benefits of aerobic exercise (AE) with blood flow restriction (BFR), these findings have been limited by the approaches used to determine the occlusive pressure. In addition, the physiological and perceptual responses of AE with BFR compared to high-intensity interval exercise (HIIE) remain unclear. Thus, we investigated the physiological and perceptual responses to AE with and without BFR, and HIIE. Twenty-two men were randomly assigned to 4 experimental conditions: AE (40% of maximal oxygen consumption [V˙o2peak]), AE with 50% of BFR (AE-BFR: 40% VV˙o2peak), HIIE (80% V˙o2peak), and a no exercise control condition (CON: 50% of BFR). Each exercise bout lasted 18 minutes, during which oxygen consumption (V˙o2), heart rate (HR), and ratings of perceived exertion (RPE) were measured at rest and at every 3 minutes during exercise. Ratings of discomfort before and after each trial. The HIIE condition induced the greatest increases in V˙o2 and HR (p < 0.05), whereas AE-BFR was significantly (p < 0.05) greater than AE and CON. HIIE and AE-BFR also elicited the greatest (p < 0.05), but similar (p > 0.05), increases in RPE during exercise, although AE-BFR was significantly greater than HIIE immediately after exercise (p < 0.05). AE-BFR and HIIE also induced similar levels of discomfort after exercise (p > 0.05). In conclusion, HIIE induced the greatest increases in V˙o2 and HR, although the perceptual responses were essentially the same compared with AE-BFR. However, albeit inferior to HIIE, V˙o2 was greater during AE-BFR compared with AE, indicating that this training method may be used to replace HIIE and still significantly elevate V˙o2., (Copyright © 2019 National Strength and Conditioning Association.)

The purpose of this study was to examine age-related differences in muscle performance in women divided into young (YW, 20-39 years, n = 29) middle-aged (MAW, 40-59 years, n = 33), and older (OW, ≥60 years, n = 40) age groups., Methods: Hand grip strength, vertical jump performance, and knee extensor (KE) strength (0 deg/s, 60 deg/s, and 240 deg/s), speed of movement (SoM; at 1 Nm, 20%, 40%, and 60% isometric strength), and endurance (30-repetition test at 60 degs/s and 240 deg/s) were assessed. Computed tomography-acquired muscle cross-sectional area (mCSA) was measured and included to determine specific strength (KE strength/mCSA)., Results: Hand grip strength was similar across groups, while jump performance declined with age (YW and MAW > OW, p < 0.001). KE strength declined significantly with age (all conditions p < 0.01), while specific strength was similar across groups. SoM was significantly higher for YW and MAW compared to OW (both p < 0.01). An age × velocity interaction revealed YW KE endurance was similar between conditions, whereas MAW and OW displayed significantly better endurance during the 60 deg/s condition. OW displayed impaired KE endurance at 240 deg/s (vs. YW and MAW, p < 0.01) but improved at 60 deg/s (vs. YW, p < 0.01). Dynamic torque decline increased with age (YW < OW, p = 0.03) and was associated with intramuscular adipose tissue (r = 0.21, p = 0.04)., Conclusions: Performance declines were most evident among OW, but few performance deficits had emerged in MAW. Interestingly, strength declines disappeared after normalizing to mCSA and endurance appears to be velocity-dependent.

Objective . The measurement of skin temperature using infrared thermography has gained a lot of attention in sport and science since it might be related to the recovery process following high intensity, potentially damaging exercise. This study investigated the time course of the skin temperature response and the muscle recovery status following a resistance training session involving leg press exercise. Approach . Fourteen young male college students (19.9 ± 1.7 years, 176 ± 6 cm, 66.1 ± 7.6 kg, 21.1 ± 1.8 kg.m -2 ) performed one session involving 10 sets, of 10 repetition maximum each (RM), of unilateral leg press 45° exercise, performed to momentary muscle failure, with 2 min rest between sets. Perceived recovery, mean and maximum thigh skin temperatures, thigh muscle thickness, maximal isometric strength, muscle soreness, and horizontal jump performance were measured pre, 24, 48, and 72 h following exercise. Main results . The exercise protocol resulted in significant reduction in isometric strength, horizontal jump performance, and perceived recovery ( p  < 0.05). There was also a significant ( p  < 0.05) increase in muscle thickness and muscle soreness. With exception of jump performance, that recovered at 48 ( p  > 0.05), recovery parameters did not recover up to 72 h post-exercise ( p  > 0.05). Surprisingly, skin temperatures were not altered throughout the entire 72 h post-exercise period ( p  > 0.05). No significant positive correlation was found between skin temperatures and muscle thickness. Additionally, only one out of 16 correlation coefficients showed significant ( r  = -0.56, p  = 0.036) inverse association between skin temperature and isometric strength. Significance . In conclusion, thigh skin temperature remains unaffected up to 72 h following a leg press exercise, and the time course response of thigh skin temperature was not associated with recovery status., (© 2021 Institute of Physics and Engineering in Medicine.)

Abstract: Heishman, AD, Daub, BD, Miller, RM, Freitas, EDS, and Bemben, MG. Longitudinal hydration assessment in collegiate basketball players over various training phases. J Strength Cond Res 35(4): 1089-1094, 2021-To the best of our knowledge, previous literature has not longitudinally examined hydration status in collegiate basketball players. Therefore, the purpose of this investigation was to examine the prepractice hydration status of collegiate basketball players across various training phases for 2 consecutive years. Retrospective analyses examined prepractice urine-specific gravity (USG) assessments obtained from National Collegiate Athletic Association (NCAA) Division I male basketball players during the preseason and competitive season, for 2 consecutive years. The first year (year 1 = Y1) of analysis consisted of 15 athletes and the second year (year 2 = Y2) consisted of 16 athletes, with 8 athletes in both seasons. Hydration status was classified based on the National Athletic Trainers' criteria: (a) euhydrated, USG < 1.020; (b) hypohydrated, USG = 1.020-1.030; and (c) significantly hypohydrated, USG > 1.030. Additional comparisons examined the association of minutes played with hydration status and changes in hydration status for athletes returning from Y1 to Y2. The results indicated 55-65.7% of cases showed levels of significant hypohydration during the preseason and competitive seasons for both years. Preseason hydration status was significantly better than the competitive season (Y1, p = 0.008; Y2, p = 0.005). Despite significant differences in minutes played (p < 0.001), no differences in hydration status were observed. Returning athletes displayed no differences in hydration status between Y1 and Y2. Collegiate basketball players show levels of hypohydration when longitudinally examined across various training phases. Although hydration may be improved in the preseason, alternative factors such as average game minutes played and length in program may not influence hydration status., (Copyright © 2018 National Strength and Conditioning Association.)

Background: Low-load resistance exercise with blood flow restriction ( LL BFR-RE) has been shown capable of improving neuromuscular parameters in several clinical populations, however, its tolerability and effects on individuals with multiple sclerosis (MS) remains unknown., Objective: To investigate the perceptual responses of individuals with MS to LL BFR-RE versus traditional high-load resistance exercise (HL-RE)., Methods: Four men and eleven women diagnosed with relapsing-remitting MS randomly completed the following experimental trials: 1) LL BFR-RE four sets of 30-15-15-15 repetitions, at 20% of one-repetition maximum (1-RM) of leg-press (LP) and knee-extension (KE), with 50% of BFR, and a 1-min rest interval between sets; 2) HL-RE- four sets of 8-10 repetitions, at 70% 1-RM of LP and KE, with the same rest intervals. Ratings of perceived exertion (RPE) were measured after each set, pain was measured before and after sets, and delayed-onset muscle soreness (DOMS) was measured at 5, 30, 60 min, and 24-h post-exercise., Results: HL-RE elicited significantly (p<0.05) greater RPE compared to LL BFR-RE during all sets. Additionally, there were no significant (p>0.05) differences between LL BFR-RE and HL-RE for pain immediately after all sets, although pain measured before sets were significantly (p<0.05) greater for LL BFR-RE. Finally, both protocols resulted in similar DOMS, however, it was significantly (p<0.05) elevated 24-h post-exercise compared to 1-h after for HL-RE but not for LL BFR-RE., Conclusion: Altogether, these data demonstrate that LL BFR-RE is well tolerated by individuals with MS, requires less muscular exertion than HL-RE, and does not cause exaggerated pain during exercise or elevated DOMS up to 24 h post-exercise., (Copyright © 2020 Elsevier Inc. All rights reserved.)

The purpose of the current investigation was to compare the acute perceptual responses during low-load resistance exercise (RE) with clinical blood flow restriction (cBFR-RE) and practical blood flow restriction (pBFR-RE), and during conventional low- (LL-RE) and high-load resistance exercise (HL-RE), to determine if these responses differed between young males and females. Twenty-nine participants (14 males: 23.6±2.7years, 25.3±3.1kg/m 2 and 15 females: 20.3±1.6years, 23.4±1.9kg/m 2 ) completed the following exercise conditions in a randomized design: 1) cBFR-RE, 2) pBFR-RE, 3) HL-RE, and 4) LL-RE. Low-load conditions consisted of 30-15-15-15 repetitions of two-leg press (LP) and knee extension (KE) exercises with 30% one-repetition maximum (1-RM), and HL-RE consisted of 3 sets of 10 repetitions at 80% 1-RM, all with 60s rest intervals. Ratings of perceived exertion (RPE) and discomfort were assessed before exercise and immediately following each set. RPE was significantly higher in HL-RE compared to all low-load conditions for both exercises after each set (all p<0.05). cBFR-RE resulted in significantly greater RPE than pBFR-RE and LL-RE for both exercises for sets 1-4 for LP and sets 2-3 for KE (all p<0.05). Levels of discomfort were similar between cBFR-RE and HL-RE, which tended to be significantly higher than pBFR-RE and LL-RE (p<0.05). Men reported significantly greater RPE than women following sets 2-4 during KE with cBFR-RE and sets 2 and 3 during KE for HL-RE (all p<0.05). Males also reported significantly greater discomfort than women following sets 2-4 for KE LL-RE (p<0.05). Altogether, these data suggest that pBFR-RE may provide a more favorable BFR condition based on perceptual responses and that perceptual responses may differ between sexes across varying resistance exercise conditions., (Copyright © 2020 Elsevier Inc. All rights reserved.)

This study compared the acute physiological responses of traditional and practical blood flow restriction resistance exercise (tBFR and pBFR, respectively) and high- and low-load resistance exercise without BFR (HL and LL, respectively), as well as the potential sex differences within the aforementioned exercise methods. Fourteen men and fifteen women randomly completed the following experimental conditions: (1) tBFR, consisting of four sets of 30-15-15-15 repetitions of the bilateral horizontal leg press and knee extension exercises, at 30% of one-repetition maximum (1-RM), with a 13.5 cm wide pneumatic cuff placed at the most proximal portion of each thigh and inflated to a pressure equivalent to 50% of the participant's total occlusion pressure; (2) pBFR, which was the same as the tBFR condition, except that an elastic band wrapped around the proximal portion of each thigh at a tightness of 7 on a 0 to 10 perceived pressure scale was used to reduce blood flow; (3) LL, same as the tBFR and pBFR protocols, except that no BFR was applied; and (4) HL, consisting of 3 sets of 10 repetitions at 80% of 1-RM, with the same 1-min rest interval between sets and a 3-min rest period between exercises. At baseline, immediately post-, 5 min post-, and 15 min post-exercise, whole-blood lactate (WBL), indices of muscle swelling (muscle thickness and thigh circumference), hematocrit and plasma volume changes, were measured as well as superficial electromyography (sEMG) amplitude during exercise. There were no significant ( p > 0.05) differences between the tBFR and pBFR exercise protocols for any of the physiological parameters assessed. However, significantly greater ( p < 0.05) WBL and sEMG values were observed for HL compared to the remaining exercise conditions. Finally, males displayed greater WBL levels than females at 15 min post-exercise. Interestingly, males also displayed significantly ( p < 0.05) greater sEMG amplitude than females within the low-load trials during leg press, but no significant ( p < 0.05) sex differences were observed during knee extension. In conclusion, tBFR and pBFR seemed to be capable of inducing the same acute physiological responses. Furthermore, males displayed greater responses than females for some of the physiological parameters measured., (Copyright © 2020 Freitas, Galletti, Koziol, Miller, Heishman, Black, Bemben and Bemben.)

The aim of the current study was to investigate the effects of horizontal and incline bench press as well as the combination of both exercises on neuromuscular adaptation in untrained young men. Forty-seven untrained men were randomly assigned to one of the three groups: 1) a horizontal bench press group (n= 15), 2) an incline bench press group (n= 15), and 3) a combination (horizontal + incline) group (n= 17). Training was conducted once a week for eight weeks, with equalized number of sets among groups. Muscle thickness, isometric strength and electromyography (EMG) amplitude of the pectoralis major were measured one week before and after the training period. There was no difference between groups for the change in horizontal bench press isometric strength (~ 10 kg increase, p=0.776) or incline bench press isometric strength (~ 11 kg increase, p=0.333). Changes in muscle thickness differed only in one of the three sites. The changes in the second intercostal space of the pectoralis major was greatest in the incline pressure group compared with the horizontal [mean difference (95% CI) of 0.62 (0.23, 1.0) cm, p=0.003] and combination groups [mean difference (95% CI) of 0.50 (0.14, 0.86) cm, p=0.008]. The change in EMG amplitude following training differed between groups in only one out of the four sites. The present results indicate that strength and conditioning professionals might consider that horizontal and incline bench press exercises, or a combination of both exercises can render similar change in general strength.

The coronavirus disease 2019 (COVID-19) has spread to at least 115 countries and caused an alarming number of deaths. The current outbreak has lead authorities from many countries to adopt several protective measures, including lockdown and social distancing. Although being a reasonable measure to counteract the COVID-19 contamination, the restrictive measures have limited individual's ability to perform exercise outdoors or in gyms and similar facilities, thus raising the risks for chronic health conditions related to a sedentary lifestyle. The recent exercise recommendations to counteract the potential deleterious effects of COVID-19-related lockdown have not fully addressed resistance exercise interventions as potential home-based exercise strategies. Additionally, the following questions have been constantly raised: (1) Is training status capable of protecting an individual from COVID-19 infection?; and (2) Can a single endurance or resistance exercise session acutely increase the risks for COVID-19 infection? Therefore, the current mini review aimed to focus on these two concerns, as well as to discuss the potential use of practical blood flow restriction and no load resistance training as possible resistance exercise strategies that could be performed during the current COVID-19 pandemic., (Copyright © 2020 Ferreira-Júnior, Freitas and Chaves.)

Miller, RM, Heishman, AD, Freitas, EDS, and Bemben, MG. Evaluating the effects of underloaded and overloaded warm-ups on subsequent swing velocity. J Strength Cond Res 34(4): 1071-1077, 2020-Several attempts to identify the optimal on-deck procedure to enhance swing velocity in baseball have been made. However, inconsistent findings continue to constitute much of the body of literature. In addition, the emergence of athlete monitoring in sport has led to the exploration of more sport-specific tasks to potentially identify athlete fatigue and readiness to perform. Therefore, the purpose of this investigation was to examine 3 different bat weight warm-up protocols on subsequent swing velocity and to examine the reliability of swing velocity measurements to allude to its potential a sport-specific athlete monitoring metric. Thirty-two recreational male baseball players 20.3 ± 2.0 years, 179.6 ± 7.1 cm and 89.6 ± 11.1 kg completed the study. Subjects completed 3 testing visits that included warming up with a control bat ([CB] 32 in., 29 oz), plastic bat ([PB] 31 in., 6.4 oz), or heavy bat ([HB] 32 in., 57 oz). Testing visits began with 3 CB swing trials followed by 3 intervention bat trials, then concluded with 3 additional CB swings. Swing velocity was assessed using visual 3D technology. Analyses of variance indicate that after the PB (26.6 ± 2.0 m·s) and CB interventions (26.2 ± 1.7 m·s) significantly faster (p < 0.001) swing velocities were generated when compared with the traditional HB intervention (24.1 ± 2.2 m·s). When assessed for reliability, the average ICC was 0.681 and Cronbach's alpha was 0.95, indicating exceptional reliability. Congruent to previous research, these data bolster the notion that warming up with a HB can hinder swing velocity. However, in contrast to previous research these data suggest that using a PB can increase swing velocity significantly. Furthermore, visual 3D can be designated as an exceptionally reliable device to measure swing velocity.

The primary goal of this investigation was to examine the physiological responses of blood flow restriction (BFR) resistance exercise (RE) performed with continuous or intermittent BFR and to compare these results to those from conventional high- and low-load RE without BFR. Fourteen men randomly completed the following experimental trials: (1) low-load RE with continuous BFR (cBFR), (2) low-load RE with intermittent BFR (iBFR), (3) low-load RE without BFR (LI), and (4) conventional high-load RE without BFR (HI). For the cBFR, iBFR, and LI exercise trials, participants performed four sets of 30-15-15-15 repetitions of the bilateral leg press (LP) and knee extension (KE) exercises, at an intensity of 20% of their one-repetition maximum (1-RM), at a 1.5-s contraction speed, and with a 1-min rest period between sets. The only difference between the cBFR and iBFR protocols was that the pressure of the cuffs was released during the rest intervals between sets for the iBFR trial. For the HI trial, participants completed four sets of 10 repetitions of the same exercises, at 70% of 1-RM, with a 1-min rest period between sets, and at the same contraction speed. Muscle activity was assessed during each set using superficial electromyography, as well as changes in blood lactate concentration [La - ] from baseline at 5 min post exercise and in muscle swelling and plasma volume (%ΔPV) at 5 and 15 min post exercise. There were no significant differences in muscle activity ( p < 0.05) across the cBFR, iBFR, and LI protocols at any time point, whereas they were all significantly lower than HI. There were also no significant ( p < 0.05) differences across the three low-load RE conditions for [La - ],%ΔPV, or muscle swelling. HI elicited significantly ( p < 0.05) greater responses than cBFR, iBFR, and LI for all the physiological markers measured. In conclusion, RE combined with cBFR or iBFR induce the same acute physiological responses. However, the largest physiological responses are observed with HI, probably because of the significantly greater exercise volumes. Therefore, releasing the pressure of the restrictive cuffs during the rest periods between sets will not hinder the acute physiological responses from BFR RE., (Copyright © 2020 Freitas, Miller, Heishman, Ferreira-Júnior, Araújo and Bemben.)

Limited research has paralleled concomitant changes in external training load (eTL) and countermovement jump (CMJ) performance. Therefore, this investigation characterized eTL and CMJ performance changes across preseason training in Division 1 male collegiate basketball athletes, while examining the influence of position (Guard vs. Forward/Center) and scholarship status (Scholarship = S vs. Walk-on = WO). During 22 practices, eTL was monitored in 14 male athletes, with weekly CMJs performed to quantify neuromuscular performance (Jump Height [JH], Flight Time:Contraction Time [FT:CT], Reactive Strength Index Modified [RSI Mod ]). PlayerLoad per minute was significantly higher during W1 and W2 (5.4 ± 1.3au and 5.3 ± 1.2au, respectively; p < 0.05) compared to subsequent weeks, but no additional differences in eTL parameters across time were observed. Scholarship athletes displayed greater PlayerLoad (S = 777.1 ± 35.6, WO = 530.1 ± 56.20; Inertial Movement Analysis (IMA) IMA&#95;High (S = 70.9 ± 15.2, WO = 41.3 ± 15.2); IMA&#95;Medium (S = 159.9 ± 30.7, WO = 92.7 ± 30.6); and IMA&#95;Low (S = 700.6 ± 105.1, WO = 405 ± 105.0;) (p < 0.05), with no observed differences in eTL by position. Moderate decreases in FT:CT and RSI Mod paralleled increased eTL. Significant increases in practice intensity (W1 and W2) did not impact CMJ performance, suggesting athletes could cope with the prescribed training loads. However, moderate perturbations in FT:CT and RSI Mod paralleled the weeks with intensified training. Cumulatively, scholarship status appears to influence eTL while player position does not., (© Journal of Sports Science and Medicine.)

Miller, RM, Freitas, EDS, Heishman, AD, Koziol, KJ, Galletti, BAR, Kaur, J, and Bemben, MG. Test-retest reliability between free weight and machine-based movement velocities. J Strength Cond Res 34(2): 440-444, 2020-Several devices are available to measure muscular power through velocity measurement, including the Tendo FitroDyne. The ability for such devices to produce consistent results is still questioned, and the reproducibility of measurement between free weight and machine exercise has yet to be examined. Therefore, the aim of this investigation was to determine the test-retest reliability for barbell velocity during the bench press (BP) and weight velocity during the 2 leg press (2LP) for loads corresponding to 20-80% of 1 repetition maximum (1RM). Forty recreationally active individuals (22.6 ± 2.5 years; 175.9 ± 10.8 cm; and 76.2 ± 13.2 kg) with a 1RM BP and 2LP of 66.8 ± 32.4 kg and 189.5 ± 49 kg, respectively, volunteered for this study. Subjects completed 1 familiarization visit preceding 3 testing visits, which encompassed 1RM determination and 2 days of velocity testing. Forty-eight hours after 1RM testing, the subjects performed 1 repetition at 20, 30, 40, 50, 60, 70, and 80% of their 1RM for each exercise in randomized order. Subjects returned to the laboratory 1 week later to perform the velocity assessment again in randomized order. Intraclass correlation coefficient (ICC2,1) and relative SEM for the BP and 2LP ranged from 0.56 to 0.98 (3-18.1%) and 0.78 to 0.98 (2.8-7.2%), respectively, and no mean differences were observed between trials. The results suggest high reliability for BP velocity between 30 and 60% 1RM and moderate reliability at 20, 70, and 80% 1RM, while the 2LP displayed high to excellent reliability from 20 to 80% 1RM. Cumulatively, machine-based exercise displayed greater reproducibility; however, additional machine exercises need to be examined to bolster this conclusion.

Heishman, AD, Daub, BD, Miller, RM, Freitas, EDS, Frantz, BA, and Bemben, MG. Countermovement jump reliability performed with and without an arm swing in NCAA Division 1 intercollegiate basketball players. J Strength Cond Res 34(2): 546-558, 2020-The countermovement jump (CMJ) is routinely used in athlete performance to quantify adaptions to training, as well as monitor neuromuscular readiness and fatigue. However, controversy remains in whether to incorporate an arm swing during the CMJ (CMJ AS) or keep the hands placed on the hips (CMJ NAS). Incorporating the arms provides a higher degree of sport-specificity that may yield improved reliability, especially in skilled jumpers. By contrast, the hands-on-hips approach isolates lower extremity force production and eliminates potential arm-swing variation. Therefore, the purpose of this study was to establish the reliability of CMJ typical (CMJ-TYP), CMJ concentric alternative (CMJ-Conc-ALT), and CMJ eccentric alternative (CMJ-Ecc-ALT) variables obtained during the CMJ AS and CMJ NAS. Twenty-two (men = 14, women = 8) NCAA Division 1 collegiate basketball players performed 3 CMJ AS and 3 CMJ NAS on a force plate, in a randomized order. To assess the test-retest reliability, participants returned 1 week later to perform 3 additional CMJ AS and 3 CMJ NAS. Intraclass correlation coefficient (ICC) and coefficient of variation (CV) were used to assess intersession and intrasession reliability for the various CMJ variables. A majority of CMJ-TYP and several CMJ-Conc-ALT and CMJ-Ecc-ALT variables exhibited adequate intersession and intrasession reliability (ICC > 0.700 and CV <10%) during both the CMJ AS and the CMJ NAS. Countermovement jump AS may provide more pertinent information about long-term changes in sport-specific performance, whereas the CMJ NAS may be more beneficial for detecting acute changes in neuromuscular fatigue and athlete readiness.

We investigated the perceptual responses to resistance exercise (RE) with continuous and intermittent blood flow restriction (BFR). Fourteen males randomly completed the following exercise conditions: low-load RE with continuous BFR (cBFR), low-load RE with intermittent BFR (iBFR), low-load RE without BFR (LI), and traditional high-load RE (HI). Participants completed 4 sets of 30-15-15-15 repetitions of bilateral leg press and knee extension exercises during the low-load conditions, at 20% of one-repetition maximum (1-RM), a 1.5‑sec metronome-controlled pace, with a 1-min rest interval between sets; HI consisted of 4 sets of 10 repetitions of the same exercises, at 70% 1-RM, with the same pace and rest interval. Ratings of perceived exertion (RPE) and discomfort were assessed using psychometric scales before exercise and after each set. RPE displayed no significant differences (p > 0.05) between the BFR conditions for either exercise. Additionally, both BFR conditions elicited significantly (p < 0.05) greater RPE than LI and significantly (p <0.05) lower RPE than HI during both exercises. Rating of discomfort displayed no significant differences between BFR conditions during the first two sets of leg press; however, cBFR evoked greater discomfort compared to iBFR during the last two sets. There were no significant (p > 0.05) differences observed between conditions during the knee extension exercise. Rating of discomfort was similar between the BFR and HI conditions and each were significantly greater than LI during both exercises. Therefore, cBFR and iBFR seem to produce similar perceptual responses, which are greater than LI and lower than HI, but similar in regards to discomfort., (Copyright © 2019 Elsevier Inc. All rights reserved.)

Background and Purpose: Previous literature suggests that reductions in appendicular skeletal mass (ASM) may have a greater detrimental effect than total lean body mass regarding the onset and progression of sarcopenia. Unfortunately, limited access to equipment that accurately determines ASM often leads to many individuals remaining undiagnosed and experiencing functional decline. Therefore, the purpose of this investigation was to determine the ability of functional and neuromuscular measures to identify ASM in older women., Methods: Forty-one (sarcopenic n = 15) older women underwent body composition analysis via dual-energy X-ray absorptiometry (DXA) and performed the following measures: bench press (BP) 1-repetition maximum strength (1RM), vertical jump height and power, handgrip strength, Timed Up and Go test, Berg Balance Scale testing, and bench press power testing at 20%, 40%, and 60% 1RM., Results and Discussion: Regression analyses revealed 3 significant models accounting for 93.8%, 91.1%, and 86.4% of the variance in DXA-derived ASM. Paired-samples t tests revealed no significant differences between model-derived and DXA-derived ASM for each model, and each model was significantly correlated to DXA-derived ASM (P < .001). In addition, each model revealed a strong ability to appropriately classify sarcopenia status, with the area under the curve values ranging from 0.86 to 0.93. The present data indicate that ASM can be determined with high precision by measuring outcome variables such as jump power, body weight, and grip strength in older women., Conclusions: Therefore, the present models could be used to identify, screen, or classify older women as sarcopenic, ultimately allowing the implementation of interventions aimed at decreasing the difficulty of activities of daily living and increasing quality of life.

The acute and chronic effects of whole-body vibration (WBV) on balance, postural stability, and mobility were evaluated in 21 women with relapsing-remitting multiple sclerosis (MS) randomly assigned to control (n = 9) or experimental (n = 12) groups. To assess acute responses, outcome variables were assessed before and immediately after a session of WBV (five 30-second bouts of vibration; frequency 30 Hz; amplitude 3 mm; 1-minute rest intervals) during their first visit (week 1) using field (Timed-Up and Go; 500-m walk; Berg Balance Scale) and laboratory tests (NeuroCom Balance Master and EquiTest System-Sensory Organization Test, Adaptation Test, Limits of Stability, Modified Clinical Test for Sensory Integration of Balance, Unilateral Stance, Tandem Walk, Step/Quick Turn). Acute responses were also measured after their fifth visit for only the Adaptation and Sensory Organization tests. For the chronic responses, participants were exposed to the WBV protocol once a week, for a total of 5 weeks, and then at week 5, were reassessed with the Adaptation and the Sensory Organization tests. Neither acute nor chronic exposure to the WBV protocols used in this study resulted in significant improvements ( P > .05) in balance, postural stability, or mobility as assessed by either field or laboratory tests. However, based on promising results from other studies that have used WBV with other clinical populations, either alone or in conjunction with exercise, additional studies that increase the dose of vibration exposure, both acutely and chronically, should be conducted in patients with MS., Competing Interests: Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

This investigation examined the acute effects of continuous whole-body vibration (CWBV) and intermittent whole-body vibration (IWBV) on neuromuscular and functional measures in women with sarcopenia and nonsarcopenic women. Continuous whole-body vibration was one 6-minute exposure, while IWBV consisted of six 60-second exposures to rest intervals (30 Hz, 2-4 mm amplitude). Factorial analyses revealed group × exposure × time interactions for jump height (JH; F = 10.8, P = .002), grip strength (GS; F = 15.5, P < .001), timed up and go test (F = 11.7, P = .002), and sit and reach test (S&R; F = 9.7, P = .004). Both JH and GS significantly improved post-WBV in women with sarcopenia ( P < .001), with post-IWBV significantly greater ( P < .001) than post-CWBV. Timed up and go test and S&R significantly improved post-IWBV in both the groups ( P < .001) with post-IWBV significantly better than post-CWBV ( P < .001). Bench press power at 20% one repetition maximum (1RM) revealed an exposure × time interaction (F = 4.6, P = .04) illuminating that IWBV significantly improved muscular power ( P < .001). Bench press power at 40% 1RM revealed group × exposure (F = 6.4, P = .016) and exposure × time interactions (F = 5.8, P = .022). Individuals with sarcopenia significantly increased power output ( P < .001) post-IWBV which was significantly greater than post-CWBV ( P = .037). Bench press power at 60% 1RM revealed an exposure × time interaction (F = 8.6, P = .006), indicating that power was significantly improved post-IWBV ( P = .027) and decreased post-CWBV. Berg Balance scale revealed a time main effect (F = 6.64, P = .015), and pain discomfort was significantly lower post-IWBV. These data indicate IWBV may provide a more efficacious exposure pattern in older women when compared to CWBV., Competing Interests: Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Miller, RM, Keeter, VM, Freitas, EDS, Heishman, AD, Knehans, AW, Bemben, DA, and Bemben, MG. Effects of blood-flow restriction combined with postactivation potentiation stimuli on jump performance in recreationally active men. J Strength Cond Res 32(7): 1869-1874, 2018-Whole-body vibration (WBV) and maximum voluntary contractions (MVCs) combined with blood-flow restriction (BFR) to augment postactivation potentiation have yet to be examined. Therefore, the purpose of this investigation was to examine the augmented effects of postactivation potentiation when WBV and MVC are combined with BFR. Twenty men (21.8 ± 2.6 years, 180.5 ± 6.2 cm and 84.5 ± 12.1 kg) completed the study. Participants completed 3 testing sessions in a randomized design that included one of the following: (a) control (CON), (b) WBV and WBV combined with BFR (WBV + BFR), or (c) MVC and MVC combined with BFR (MVC + BFR). Jump height and power were recorded for 3 trials, PRE and POST jump height (cm) mean ± SD for each were as follows: CON 58.9 ± 8.6 and 57.9 ± 8.6, WBV 58.2 ± 8.1 and 59.9 ± 8.1, WBV + BFR 58.7 ± 7.6 and 60.2 ± 8.1, MVC 59.7 ± 7.4 and 60.2 ± 8.6, and MVC + BFR 57.7 ± 7.9 and 59.4 ± 8.1. PRE and POST jump power (W) mean ± SD for each were as follows: CON 1,224.3 ± 221.5 and 1,234.3 ± 189.2, WBV 1,251.1 ± 230.4 and 1,266.1 ± 215.7, WBV + BFR 1,265.8 ± 207.9 and 1,259 ± 223.3, MVC 1,264.7 ± 211.9 and 1,263.5 ± 236.5, and MVC + BFR 1,252.3 ± 222.0 and 1,294.6 ± 256.6. Significant differences were revealed in jump height between the 5 interventions (p < 0.01), WBV (p < 0.01), WBV + BFR (p < 0.01), and MVC + BFR (p < 0.01) revealed significant differences in time but no differences in jump power. In conclusion, the results of this study indicate that WBV, WBV + BFR, and MVC + BFR significantly improve jump height and time in air but not jump power.

This study compared the effects of different conditioning activities on the 100-m dash performance of 11 male, high school track and field athletes (mean age = 16.3; SD = 1.2 years). Participants performed a 100-m dash seven minutes after each of four randomized conditioning protocols, with each condition and 100-m dash separated by 3-10 days. The conditioning protocols were (a) control, no conditioning activity; (b) weighted plyometric, three sets of 10 repetitions of alternate leg bounding with additional load of 10% of the body mass; (c) free sprint, two 20-m sprints; and (d) resisted sprint (RS), two 20-m resisted sprints using an elastic tubing tool. We obtained session ratings of perceived exertion (SRPE) immediately after each conditioning protocol. There were no significant differences between any of the three experimental conditioning activities on 100-m sprint time, but the RS protocol improved 100-m sprint time compared with the control (no conditioning) protocol ( p < .001). The RS also led to greater sprint velocity and higher SRPE compared with the control condition ( p < .01). There was no significant association between SRPE and 100-m performance ( p = .77, r = .05). These results suggest a benefit for young male track and field athletes to the elastic tubing warm-up activities prior to the 100-m dash.

The original version of this article was published online containing two items that require correction, namely the abstract (Results section) and Table 3.

Background: Elderly people have a high prevalence to systemic arterial hypertension (SAH) and obstructive sleep apnea (OSA). Both comorbidities are closely associated and inflict damage on cardiorespiratory capacity., Methods: In order to assess cardiorespiratory responses to the cardiopulmonary exercise test (CPET) among hypertensive elderly with OSA, we enrolled 28 subjects into two different groups: without OSA (No-OSA: apnea/hypopnea index (AHI) < 5 events/h; n = 15) and with OSA (OSA: AHI ≥ 15 events/h; n = 13). All subjects underwent CPET and polysomnographic assessments. After normality and homogeneity evaluations, independent t test and Pearson's correlation were performed. The significance level employed was p ≤ 0.05., Results: Hypertensive elderly with OSA presented lower heart rate recovery (HRR) in the second minute (HRR 2 ) in relation to the No-OSA group. A negative correlation between AHI and ventilation (VE) (r = -0.63, p = 0.02) was found in polysomnography and CPET data comparisons, and oxygen saturation (O 2 S) levels significantly correlated with VE/VCO 2slope (r = 0.66, p = 0.01); in addition, OSA group presented a positive correlation between oxygen consumption and O 2 S (r = 0.60, p = 0.02), unlike the no-OSA group., Conclusions: OSA does not affect the CPET variables in hypertensive elderly, but it attenuates the HRR 2 . The association between O 2 S during sleep with ventilatory responses probably occurs due to the adaptations in the oxygen transport system unleashed via mechanical respiratory feedback; thus, it has been identified that OSA compromises the oxygen supply in hypertensive elderly.

This study determined the time course for changes in muscle swelling and plasma volume following high (HI) and low-intensity resistance exercise with blood-flow restriction (LI-BFR). Ten male participants (22.1±3.0 yrs) completed three experimental conditions: high-intensity exercise (HI - 80% of 1RM), low-intensity exercise with BFR (LI-BFR -20% of 1RM, and 160 mmHg of BFR), and control (CON - no exercise or BFR). Muscle cross-sectional area (mCSA), muscle thickness, thigh circumference, and percentage change in plasma volume (PV%∆) were measured. mCSA was significantly greater than rest values at 15 min post-exercise (p<0.01) for HI and LI-BFR, and at 75 min post-exercise (p<0.01) for HI. Muscle thickness was significantly greater than rest immediately post-exercise (p<0.01) and 30 min post-exercise (p<0.01) for HI and LI-BFR, and at 60 min post-exercise for HI (p=0.01). Muscle thickness was greater for BFR immediately post-exercise compared to HI (p=0.01) post-exercise. Thigh circumference was significantly greater from rest at 15 min post-exercise (p=0.01) and at 75 min post-exercise for both LI-BFR (p=0.03) and HI (p<0.01). PV%∆ significantly decreased from rest immediately post-exercise for both HI (p<0.01) and LI-BFR (p<0.01). In conclusion, BFR exercise induces changes in muscle swelling and plasma volume similar to those observed at high-intensities., Competing Interests: Conflicts of interest: The authors have no conflict of interest to declare., (© Georg Thieme Verlag KG Stuttgart · New York.)