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458 results on '"Fu, Xiao-long"'

19. Postoperative Radiotherapy for Resected Stage IIIA-N2 Non-small-cell Lung Cancer: A Population-Based Time-Trend Study

Author

Zeng, Wan-Qin, Feng, Wen, Xie, Li, Zhang, Chen-Chen, Yu, Wen, Cai, Xu-Wei, and Fu, Xiao-Long

Subjects
Cancer patients -- Health aspects, Lung cancer, Non-small cell -- Care and treatment, Radiotherapy -- Usage, Health
Abstract

Introduction The value of postoperative radiotherapy (PORT) for resected stage IIIA-N2 non-small-cell lung cancer (NSCLC) is controversial with few studies focusing on whether PORT always plays a part in clinical practice and generates benefits to patients across different time periods. We investigated this issue using the Surveillance, Epidemiology, and End Results Database (SEER) and assessed the temporal trends spanning 27 years. Methods Within SEER, we selected stage IIIA-N2 NSCLC patients who underwent a lobectomy or pneumonectomy and coded as receiving PORT or never receiving radiotherapy over three time periods: 1988 to 1996, 1997 to 2005, 2006 to 2014. For each period, survival analyses were performed and propensity score matching (PSM) was used in the potentially beneficial subgroup. Results 45.4% of 5568 eligible patients received PORT. The yearly PORT use rates varied largely from 27.8% to 74.4%. Overall survival (OS) was distinctly improved over the period. The application of PORT had a significant impact on survival only in period 1 and 3. In subgroup analysis, the OS benefit of PORT was significant in each period in patients with 50% or more lymph node ratio (LNR) both before (hazard ratios, and P values of 0.647, P = .002; 0.804, P = .008; 0.721, P < .001 for period 1, 2, 3, respectively) and after PSM (0.642, P = .006; 0.785, P = .004; 0.748, P = .003 for period 1, 2, 3, respectively). Conclusions The benefits of PORT are lasting and stable throughout the years in patients with LNR of 50% or more. This might provide a clue on proper patient selection for PORT application., Author(s): Wan-Qin Zeng [sup.1] , Wen Feng [sup.1] , Li Xie [sup.2] , Chen-Chen Zhang [sup.1] , Wen Yu [sup.1] , Xu-Wei Cai [sup.1] , Xiao-Long Fu [sup.1] Author Affiliations: [...]

Published
2019
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28. Molecular dynamic simulations and experimental study on pBAMO-b-GAP copolymer/energetic plasticizer mixed systems

Author

Pei Jiang-feng, Wu Zong-kai, Fu Xiao-long, Wang Jiang-ning, Song Xiu-duo, Wang Ming-xing, Sun Zhi-gangand, and Hu Yi-wen

Subjects
Toughness, chemistry.chemical_compound, Hildebrand solubility parameter, Molecular dynamics, Materials science, Chemical engineering, chemistry, Binding energy, Ultimate tensile strength, Copolymer, Plasticizer, General Medicine, Oxetane
Abstract

In order to investigate the effects of plasticizers on the binding energy, solubility parameter and mechanical properties of pBAMO-b-GAP copolymer (the copolymer of 3,3’-bis(azidomethy) oxetane and glycidyl azide polymer), the related copolymer/plasticizer mixed systems were established by molecular dynamics simulations. Besides, the mechanical properties of the formulas based on pBAMO-b-GAP containing the three energetic plasticizers were also studied experimentally. The results showed that all involved energetic plasticizers could be miscible with the pBAMO-b-GAP. The order of binding energy was theoretically found to be pBAMO-b-GAP / BuNENA > pBAMO-b-GAP/ TMETN > pBAMO-b-GAP/ DIANP which was consistent with the trends of the experimental tensile strength values of three mixed materials. Excitedly, the DIANP showed strongest effects among the three plasticizers on improving the toughness of the copolymer according to the calculation of Cauchy pressure and experimental value of elongation. For the pBAMO-b-GAP copolymer, the DIANP could be a promising plasticizer and compolymer/plasticizer mixed system was suitable used as binder in azido polyether-based propellants.

Published
2022

35. Additional file 1 of PET-based radiomics visualizes tumor-infiltrating CD8 T cell exhaustion to optimize radiotherapy/immunotherapy combination in mouse models of lung cancer

Author

Zhang, Ying, Hu, Hui-Hui, Zhou, Shi-Hong, Xia, Wu-Yan, Zhang, Yan, Zhang, Jian-Ping, Fu, Xiao-Long, and Yu, Wen

Abstract

Additional file 1: Fig S1. Representative flow cytometry gating strategy for early-exhausted (PD-1int) and terminally-exhausted (PD-1hi) CD8+ T cells isolated from the tumor of a LLC mouse.

Published
2023
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45. CD45+CD33lowCD11bdim myeloid-derived suppressor cells suppress CD8+ T cell activity via the IL-6/IL-8-arginase I axis in human gastric cancer

Author

Mao, Fang-yuan, Zhao, Yong-liang, Lv, Yi-pin, Teng, Yong-sheng, Kong, Hui, Liu, Yu-gang, Wu, Xiao-long, Hao, Chuan-jie, Chen, Weisan, Duan, Mu-bing, Han, Bin, Ma, Qiang, Wang, Ting-ting, Peng, Liu-sheng, Zhang, Jin-yu, Cheng, Ping, Su, Chong-yu, Fu, Xiao-long, Zou, Quan-ming, Guo, Gang, Guo, Xiao-lan, and Zhuang, Yuan

Published
2018
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49. Recent Application Progress of Online Photo ionization Mass Spectrometry in Study of Pyrolysis of Energetic Materials.

Author

REN Hai-rong, CUl Cun-hao, OU-YANG Jian-feng, LIU Hao-ran, FU Xiao-long, GAO Hong-xu, ZHOU Zhong-yue, and Ql Fei

Subjects
PYROLYSIS, CHEMICAL ionization mass spectrometry, ATMOSPHERIC pressure, MASS spectrometry, DATABASES, MATERIALISM, ANALYTICAL chemistry
Abstract

Several commonly used detection methods in the pry-Olympics study of energetic materialism with their advantages and disadvantages were bile-fly introduced. The "soft" ionization characteristics of routinizations mass spec--Tome-qty (PI MS) and As advantages in the analysis of pry-colitis produces were described. "Soft" ionization can make the hp-duces ionize without genera-ion of ionization fragments, which is convenient of- the sapid analysis of complex systems. It is conducive to online detection of the rapidly evolving inter-mediates generated from the pry-Olympics hp-chess of energetic materialism. Recent application hp-ogress of PI MS in study of pyrolysis of energetic materialism, such as NOT, FOX-7, FOX-12 and JCL-20, we-e summarized emphatically. The PI MS methods used in these studies include Jingle photon ionization mass spec--Tome-qty and atmospheric pressure pontoon-anion high -resolution mass spec--Tome-qty based on vacuum UI-ravioli (VU) bight generated from disc ha-GE lamp O- synch-O---on -radiation sources. The new pry-colitis hp-duchies and inter-mediates detected by online PI MS were ISO summarized. Finally, he future-e opportunities of PI MS in study of gene-genic materialism we-e hp-inspected. Of- characterization of fast -reactions, by Hopi-mazing he mass spec--mete- and developing high-lightness routinizations sources, it is expected to achieve Jaime-resolved measurement at millisecond O- sub-millisecond. It will help to study the pry-colitis and combustion hp-chess of gene-genic materialism undue- high temperature and high hp-assure. Of- quantitative/e measurement, it is necessary to establish and imp-rove he pontoon-action ac-doss section database of energetic materialism and main hp-duchies. 61 Refed-fences were attached. [ABSTRACT FROM AUTHOR]

Published
2023
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