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302 results on '"Fujimori, Juichi"'

5. White blood cell count profiles in anti-aquaporin-4 antibody seropositive neuromyelitis optica spectrum disorder and anti-myelin oligodendrocyte glycoprotein antibody-associated disease

Author

Akaishi, Tetsuya, Misu, Tatsuro, Fujihara, Kazuo, Nakaya, Kumi, Nakaya, Naoki, Nakamura, Tomohiro, Kogure, Mana, Hatanaka, Rieko, Itabashi, Fumi, Kanno, Ikumi, Kaneko, Kimihiko, Takahashi, Toshiyuki, Fujimori, Juichi, Takai, Yoshiki, Nishiyama, Shuhei, Ishii, Tadashi, Aoki, Masashi, Nakashima, Ichiro, and Hozawa, Atsushi

Published
2023
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9. Slowly expanding lesions are associated with disease activity and gray matter loss in relapse‐onset multiple sclerosis.

Author

Yokote, Hiroaki, Miyazaki, Yusei, Fujimori, Juichi, Nishida, Yoichiro, Toru, Shuta, Niino, Masaaki, Nakashima, Ichiro, Miura, Yoshiharu, and Yokota, Takanori

Subjects
JAPANESE people, CEREBRAL atrophy, GRAY matter (Nerve tissue), ASIANS, MULTIPLE comparisons (Statistics)
Abstract

Background and Purpose: Slowly expanding lesions (SELs) have been proposed as novel MRI markers of chronic active lesions in multiple sclerosis (MS). However, the mechanism through which SELs affect brain volume loss in patients with MS remains unknown. Additionally, the prevalence and significance of SELs in Asian patients with MS remain unclear. This study aimed to investigate the association between SELs and no evidence of disease activity (NEDA)‐3 status as well as brain volume loss in Japanese patients. Methods: A total of 99 patients with relapse‐onset MS were retrospectively evaluated. SELs were identified on brain MRI based on local deformation when consecutive scans were registered longitudinally. We developed a logistic regression model and generalized linear mixed models (GLMMs) to evaluate the association between the number of SELs and disease activity and changes in brain volume. Results: During the observation period (2.0 ± 0.22 years), 35 patients developed at least one SEL. Multivariable logistic regression analysis showed that ≥2 SELs were associated with 0.2 times the risk of achieving a NEDA‐3 status. GLMMs revealed that the number of SELs was negatively associated with volume changes in the cortex (p =.00169) and subcortical gray matter (p =.00964) after correction for multiple comparisons. Conclusion: SELs were identified in Japanese patients with MS during the 2‐year observation period. The number of SELs is associated with disease activity and brain volume loss, suggesting that the number of SELs could be a biomarker of disease activity in MS. [ABSTRACT FROM AUTHOR]

Published
2024
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22. White blood cell count profiles in multiple sclerosis during attacks before the initiation of acute and chronic treatments

Author

Akaishi, Tetsuya, Misu, Tatsuro, Fujihara, Kazuo, Nakaya, Naoki, Nakamura, Tomohiro, Kogure, Mana, Hatanaka, Rieko, Itabashi, Fumi, Kanno, Ikumi, Takahashi, Toshiyuki, Kuroda, Hiroshi, Fujimori, Juichi, Takai, Yoshiki, Nishiyama, Shuhei, Kaneko, Kimihiko, Ishii, Tadashi, Aoki, Masashi, Nakashima, Ichiro, and Hozawa, Atsushi

Published
2021
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23. Myelin oligodendrocyte glycoprotein antibody‐associated disorders: An overview

Author

Misu, Tatsuro, primary, Matsumoto, Yuki, additional, Kaneko, Kimihiko, additional, Takahashi, Toshiyuki, additional, Takai, Yoshiki, additional, Ono, Hirohiko, additional, Namatame, Chihiro, additional, Nishiyama, Shuhei, additional, Fujimori, Juichi, additional, Kuroda, Hiroshi, additional, Nakashima, Ichiro, additional, Fujihara, Kazuo, additional, and Aoki, Masashi, additional

Published
2023
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27. Myelin oligodendrocyte glycoprotein antibody‐associated disorders: An overview.

Author

Misu, Tatsuro, Matsumoto, Yuki, Kaneko, Kimihiko, Takahashi, Toshiyuki, Takai, Yoshiki, Ono, Hirohiko, Namatame, Chihiro, Nishiyama, Shuhei, Fujimori, Juichi, Kuroda, Hiroshi, Nakashima, Ichiro, Fujihara, Kazuo, and Aoki, Masashi

Subjects
MYELIN oligodendrocyte glycoprotein, POSTVACCINAL encephalitis, ENCEPHALOMYELITIS, OPTIC neuritis, DEMYELINATION, NEUROLOGICAL disorders
Abstract

In recent years, there is growing evidence of associations between antibodies against myelin oligodendrocyte glycoprotein (MOG) and several phenotypes of acute inflammatory demyelinating diseases such as acute disseminated encephalomyelitis (ADEM), optic neuritis, brainstem, and cerebral cortical encephalitis, called MOG antibody associated disorders (MOGAD). Monophasic course is known in about half of cases especially in pediatric onset ADEM and optic neuritis, mainly in cases with transient positivity of MOG antibody. Pathological features of MOGAD are considered as acute demyelinating lesions with CD4 dominant cell infiltrations, the deposition of humoral immunity, perivascular inflammation and perivenous demyelination, which is distinct from multiple sclerosis. Now the diagnosis of MOGAD is based on the international panel criteria of MOGAD launched in 2023, which the diagnostic frameworks are three parts, including MOGAD‐specific clinical features, MOG antibody positivity, and the exclusion of other diseases. The prognosis of MOGAD patients is considered relatively mild, but the problem is refractory relapsing cases. For its prevention, there are no approved drugs, but oral tapering corticosteroids, immunosuppressants such as azathioprine and mycophenolic mofetil, rituximab, and the maintenance intravenous immunoglobulin are recommended, and now there are a few clinical trials of promising biological drugs already approved in other neurological disorders. [ABSTRACT FROM AUTHOR]

Published
2024
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28. Myelin oligodendrocyte glycoprotein antibody-associated disease in a patient with symptoms of aseptic meningitis who achieved spontaneous remission: A case report and review of the literature

Author

Hino-Fukuyo, Naomi, primary, Kawai, Eiichiro, additional, Itoh, Sakiko, additional, Oba, Shuhei, additional, Sato, Yukie, additional, Abe, Sei, additional, Ichikawa, Yukari, additional, Kitazawa, Hiroshi, additional, Atobe, Yuri, additional, Fujimori, Juichi, additional, Nakashima, Ichiro, additional, Takahashi, Toshiyuki, additional, and Morimoto, Tetsuji, additional

Published
2023
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33. sj-pptx-5-msj-10.1177_13524585231156736 – Supplemental material for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey

Author

Nakamura, Masashi, Ogawa, Ryo, Fujimori, Juichi, Uzawa, Akiyuki, Sato, Yasunori, Nagashima, Kengo, Kuriyama, Nagato, Kuwabara, Satoshi, and Nakashima, Ichiro

Subjects
FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, sj-pptx-5-msj-10.1177_13524585231156736 for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey by Masashi Nakamura, Ryo Ogawa, Juichi Fujimori, Akiyuki Uzawa, Yasunori Sato, Kengo Nagashima, Nagato Kuriyama, Satoshi Kuwabara and Ichiro Nakashima in Multiple Sclerosis Journal

Published
2023
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34. sj-docx-12-msj-10.1177_13524585231156736 – Supplemental material for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey

Author

Nakamura, Masashi, Ogawa, Ryo, Fujimori, Juichi, Uzawa, Akiyuki, Sato, Yasunori, Nagashima, Kengo, Kuriyama, Nagato, Kuwabara, Satoshi, and Nakashima, Ichiro

Subjects
FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, sj-docx-12-msj-10.1177_13524585231156736 for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey by Masashi Nakamura, Ryo Ogawa, Juichi Fujimori, Akiyuki Uzawa, Yasunori Sato, Kengo Nagashima, Nagato Kuriyama, Satoshi Kuwabara and Ichiro Nakashima in Multiple Sclerosis Journal

Published
2023
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35. sj-pptx-2-msj-10.1177_13524585231156736 – Supplemental material for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey

Author

Nakamura, Masashi, Ogawa, Ryo, Fujimori, Juichi, Uzawa, Akiyuki, Sato, Yasunori, Nagashima, Kengo, Kuriyama, Nagato, Kuwabara, Satoshi, and Nakashima, Ichiro

Subjects
FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, sj-pptx-2-msj-10.1177_13524585231156736 for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey by Masashi Nakamura, Ryo Ogawa, Juichi Fujimori, Akiyuki Uzawa, Yasunori Sato, Kengo Nagashima, Nagato Kuriyama, Satoshi Kuwabara and Ichiro Nakashima in Multiple Sclerosis Journal

Published
2023
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36. sj-docx-9-msj-10.1177_13524585231156736 – Supplemental material for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey

Author

Nakamura, Masashi, Ogawa, Ryo, Fujimori, Juichi, Uzawa, Akiyuki, Sato, Yasunori, Nagashima, Kengo, Kuriyama, Nagato, Kuwabara, Satoshi, and Nakashima, Ichiro

Subjects
FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, sj-docx-9-msj-10.1177_13524585231156736 for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey by Masashi Nakamura, Ryo Ogawa, Juichi Fujimori, Akiyuki Uzawa, Yasunori Sato, Kengo Nagashima, Nagato Kuriyama, Satoshi Kuwabara and Ichiro Nakashima in Multiple Sclerosis Journal

Published
2023
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37. sj-docx-6-msj-10.1177_13524585231156736 – Supplemental material for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey

Author

Nakamura, Masashi, Ogawa, Ryo, Fujimori, Juichi, Uzawa, Akiyuki, Sato, Yasunori, Nagashima, Kengo, Kuriyama, Nagato, Kuwabara, Satoshi, and Nakashima, Ichiro

Subjects
FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, sj-docx-6-msj-10.1177_13524585231156736 for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey by Masashi Nakamura, Ryo Ogawa, Juichi Fujimori, Akiyuki Uzawa, Yasunori Sato, Kengo Nagashima, Nagato Kuriyama, Satoshi Kuwabara and Ichiro Nakashima in Multiple Sclerosis Journal

Published
2023
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38. sj-pptx-3-msj-10.1177_13524585231156736 – Supplemental material for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey

Author

Nakamura, Masashi, Ogawa, Ryo, Fujimori, Juichi, Uzawa, Akiyuki, Sato, Yasunori, Nagashima, Kengo, Kuriyama, Nagato, Kuwabara, Satoshi, and Nakashima, Ichiro

Subjects
FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, sj-pptx-3-msj-10.1177_13524585231156736 for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey by Masashi Nakamura, Ryo Ogawa, Juichi Fujimori, Akiyuki Uzawa, Yasunori Sato, Kengo Nagashima, Nagato Kuriyama, Satoshi Kuwabara and Ichiro Nakashima in Multiple Sclerosis Journal

Published
2023
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39. sj-docx-8-msj-10.1177_13524585231156736 – Supplemental material for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey

Author

Nakamura, Masashi, Ogawa, Ryo, Fujimori, Juichi, Uzawa, Akiyuki, Sato, Yasunori, Nagashima, Kengo, Kuriyama, Nagato, Kuwabara, Satoshi, and Nakashima, Ichiro

Subjects
FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, sj-docx-8-msj-10.1177_13524585231156736 for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey by Masashi Nakamura, Ryo Ogawa, Juichi Fujimori, Akiyuki Uzawa, Yasunori Sato, Kengo Nagashima, Nagato Kuriyama, Satoshi Kuwabara and Ichiro Nakashima in Multiple Sclerosis Journal

Published
2023
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40. sj-pptx-1-msj-10.1177_13524585231156736 – Supplemental material for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey

Author

Nakamura, Masashi, Ogawa, Ryo, Fujimori, Juichi, Uzawa, Akiyuki, Sato, Yasunori, Nagashima, Kengo, Kuriyama, Nagato, Kuwabara, Satoshi, and Nakashima, Ichiro

Subjects
FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, sj-pptx-1-msj-10.1177_13524585231156736 for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey by Masashi Nakamura, Ryo Ogawa, Juichi Fujimori, Akiyuki Uzawa, Yasunori Sato, Kengo Nagashima, Nagato Kuriyama, Satoshi Kuwabara and Ichiro Nakashima in Multiple Sclerosis Journal

Published
2023
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41. sj-docx-7-msj-10.1177_13524585231156736 – Supplemental material for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey

Author

Nakamura, Masashi, Ogawa, Ryo, Fujimori, Juichi, Uzawa, Akiyuki, Sato, Yasunori, Nagashima, Kengo, Kuriyama, Nagato, Kuwabara, Satoshi, and Nakashima, Ichiro

Subjects
FOS: Clinical medicine, 111702 Aged Health Care, FOS: Health sciences, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, sj-docx-7-msj-10.1177_13524585231156736 for Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey by Masashi Nakamura, Ryo Ogawa, Juichi Fujimori, Akiyuki Uzawa, Yasunori Sato, Kengo Nagashima, Nagato Kuriyama, Satoshi Kuwabara and Ichiro Nakashima in Multiple Sclerosis Journal

Published
2023
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42. Health-related quality of life in Japanese patients with multiple sclerosis

Author

Niino, Masaaki, primary, Fukumoto, Shoko, additional, Okuno, Tatsusada, additional, Sanjo, Nobuo, additional, Fukaura, Hikoaki, additional, Mori, Masahiro, additional, Ohashi, Takashi, additional, Takeuchi, Hideyuki, additional, Shimizu, Yuko, additional, Fujimori, Juichi, additional, Kawachi, Izumi, additional, Kira, Jun-ichi, additional, Takahashi, Eri, additional, Miyazaki, Yusei, additional, and Mifune, Nobuhiro, additional

Published
2022
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45. sj-docx-1-mso-10.1177_20552173211070749 - Supplemental material for Usefulness of two-dimensional measurements for the evaluation of brain volume and disability in multiple sclerosis

Author

Ajitomi, Satori, Fujimori, Juichi, and Nakashima, Ichiro

Subjects
FOS: Clinical medicine, 110904 Neurology and Neuromuscular Diseases, Neuroscience
Abstract

Supplemental material, sj-docx-1-mso-10.1177_20552173211070749 for Usefulness of two-dimensional measurements for the evaluation of brain volume and disability in multiple sclerosis by Satori Ajitomi, Juichi Fujimori and Ichiro Nakashima in Multiple Sclerosis Journal ��� Experimental, Translational and Clinical

Published
2022
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46. sj-doc-2-mso-10.1177_20552173211070749 - Supplemental material for Usefulness of two-dimensional measurements for the evaluation of brain volume and disability in multiple sclerosis

Author

Ajitomi, Satori, Fujimori, Juichi, and Nakashima, Ichiro

Subjects
FOS: Clinical medicine, 110904 Neurology and Neuromuscular Diseases, Neuroscience
Abstract

Supplemental material, sj-doc-2-mso-10.1177_20552173211070749 for Usefulness of two-dimensional measurements for the evaluation of brain volume and disability in multiple sclerosis by Satori Ajitomi, Juichi Fujimori and Ichiro Nakashima in Multiple Sclerosis Journal ��� Experimental, Translational and Clinical

Published
2022
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