2,220 results on '"Fujioka, T."'
Search Results
2. Ultrasonographic evaluation of the caudal vena cava in dogs with right-sided heart disease
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Fujioka, T., Nakamura, K., Minamoto, T., Tsuzuki, N., Yamaguchi, J., and Hidaka, Y.
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- 2021
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3. SIRIUS Performance: 10Be, 26Al and 36Cl measurements at ANSTO
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Wilcken, K.M., Fujioka, T., Fink, D., Fülöp, R.H., Codilean, A.T., Simon, K., Mifsud, C., and Kotevski, S.
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- 2019
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4. A phase I/II study of cancer peptide vaccine S-288310 in patients with advanced urothelial carcinoma of the bladder
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Obara, W., Eto, M., Mimata, H., Kohri, K., Mitsuhata, N., Miura, I., Shuin, T., Miki, T., Koie, T., Fujimoto, H., Minami, K., Enomoto, Y., Nasu, T., Yoshida, T., Fuse, H., Hara, I., Kawaguchi, K., Arimura, A., and Fujioka, T.
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- 2017
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5. Attenuated relationship between salivary oxytocin levels and attention to social information in adolescents and adults with autism spectrum disorder: a comparative study
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Fujioka, T., Fujisawa, T. X., Inohara, K., Okamoto, Y., Matsumura, Y., Tsuchiya, K. J., Katayama, T., Munesue, T., Tomoda, A., Wada, Y., and Kosaka, H.
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- 2020
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6. Editorial: Oscillatory brain activity as a marker of brain function and dysfunction in aging and in neurodegenerative disorders
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Kielar, A., Shah-Basak, P., Meyer, L., and Fujioka, T.
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Aging ,Cognitive Neuroscience - Published
- 2023
7. Geomorphic imprints of lithospheric flexure in central Australia
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Jansen, J.D., primary, Sandiford, M., additional, Fujioka, T., additional, Cohen, T.J., additional, Struck, M., additional, Anderson, S.P., additional, Anderson, R.S., additional, Wilcken, K., additional, and Egholm, D.L., additional
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- 2022
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8. 橋梁断面の出来形検測の全自動化─システム開発と現場実装への取組み─
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Takaoka, R., primary and Fujioka, T., additional
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- 2022
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9. 鉄筋やPC鋼材を使用しない道路橋の実用化─徳島自動車道 別埜谷橋の建設─
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Fujioka, T., primary, Tashiro, N., additional, Matsuo, Y., additional, and Wada, Y., additional
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- 2022
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10. Avoidance Method Study for SAGBO Cracking During Heat Treatment of a ITER CS Model Coil Conductor Using Incoloy 908 Jacket
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Kato, T., Hamada, K., Yamamoto, K., Watanabe, I., Ishio, K., Ando, T., Tsuji, H., Abe, T., Kikuchi, K., Minakawa, N., Tsuchiya, M., Tsubota, M., Katayama, Y., Ikeda, S., Ogata, H., Fujioka, T., Osaki, A., Balachandran, U. Balu, editor, Gubser, Donald G., editor, Hartwig, K. Ted, editor, Reed, Richard P., editor, Warnes, William H., editor, and Bardos, Victoria A., editor
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- 1998
- Full Text
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11. Original research: Second IVIg course in Guillain-Barré syndrome with poor prognosis: the non-randomised ISID study
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Verboon, C, van den Berg, B, Cornblath, Dr, Venema, E, Gorson, Kc, Lunn, Mp, Lingsma, H, Van den Bergh, P, Harbo, T, Bateman, K, Pereon, Y, Sindrup, Sh, Kusunoki, S, Miller, J, Islam, Z, Hartung, Hp, Chavada, G, Jacobs, Bc, Hughes, Rac, van Doorn PA, Ajroud-Driss S, IGOS Consortium., Antonini, G, Attarian, S, Barroso, Fa, Benedetti, L, Bertorini, Te, Brannagan, Th, Briani, C, Bhavaraju-Sanka, R, Butterworth, S, Casasnovas, C, Cavaletti, G, Chen, S, Claeys, Kg, Cosgrove, Js, Davidson, A, Dardiotis, E, Dornonville de la Cour, C, Faber, Cg, Feasby, Te, Fujioka, T, Galassi, G, Gilchrist, Jm, Goyal, Na, Granit, V, Gutiérrez-Gutiérrez, G, Hadden, Rdm, Holt, Jkl, Htut, M, Jericó Pascual, I, Karafiath, S, Katzberg, Hd, Kiers, L, Kieseier, Bc, Kimpinski, K, Kuwabara, S, Kwan, Jy, Ladha, Ss, Lawson, V, Lehmann, H, Manji, H, Marfia, Ga, Márquez Infante, C, Mattiazzi, Mg, Mcdermott, Cj, Monges, Ms, Morís de la Tassa, G, Nascimbene, C, Nobile Orazio, E, Nowak, Rj, Osei-Bonsu, M, Pardo Fernandez, J, Querol Gutierrez, L, Reisin, R, Rinaldi, S, Rojas-Marcos, I, Rudnicki, Sa, Schenone, A, Sedano Tous MJ, Shahrizaila, N, Sheikh, K, Silvestri, Nj, Sommer, Cl, Varrato, Jd, Verschuuren, J, Vytopil, Mv, Zhou, L, Bella, Ir, Bunschoten, C, Bürmann, J, Busby, M, Chao, Cc, Conti, Me, Dalakas, Mc, Van Damme, P, Doets, A, van Dijk GW, Dimachkie, Mm, Doppler, K, Echaniz-Laguna, A, Eftimov, F, Fazio, R, Fokke, C, Fulgenzi, Ea, Garssen, Mpj, Gijsbers, Cj, Gilhuis, J, Grapperon, A, Hsieh, St, Illa, I, Islam, B, Jellema, K, Kaida, K, Kokubun, N, Kolb, N, van Koningsveld, R, van der Kooi AJ, Kuitwaard, K, Landschoff Lassen, L, Leonhard, Se, Mandarakas, M, Martinez Hernandez, E, Mohammad, Qd, Pulley, M, Rajabally, Ya, Reddel, Sw, van der Ree, T, Roodbol, J, Sachs, Gm, Samijn, Jpa, Santoro, L, Stein, B, Vermeij, Fh, Visser, Lh, Willison, Hj, Wirtz, P, Zivkovich, Sa., Neurology, Public Health, Immunology, and ANS - Neuroinfection & -inflammation
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Adult ,Male ,second IVIg course ,Pediatrics ,medicine.medical_specialty ,Poor prognosis ,Time Factors ,Guillain-Barre Syndrome ,Original research ,Drug Administration Schedule ,Disease course ,Disability Evaluation ,03 medical and health sciences ,0302 clinical medicine ,hemic and lymphatic diseases ,Clinical endpoint ,Humans ,Immunologic Factors ,Medicine ,In patient ,Aged ,treatment ,Guillain-Barre syndrome ,business.industry ,Immunoglobulins, Intravenous ,Middle Aged ,poor prognosis ,Prognosis ,Guillain-Barré syndrome ,medicine.disease ,Psychiatry and Mental health ,Treatment Outcome ,Immunoglobulin G ,030220 oncology & carcinogenesis ,Female ,Surgery ,Observational study ,Neurology (clinical) ,business ,030217 neurology & neurosurgery - Abstract
ObjectiveTo compare disease course in patients with Guillain-Barré syndrome (GBS) with a poor prognosis who were treated with one or with two intravenous immunoglobulin (IVIg) courses.MethodsFrom the International GBS Outcome Study, we selected patients whose modified Erasmus GBS Outcome Score at week 1 predicted a poor prognosis. We compared those treated with one IVIg course to those treated with two IVIg courses. The primary endpoint, the GBS disability scale at 4 weeks, was assessed with multivariable ordinal regression.ResultsOf 237 eligible patients, 199 patients received a single IVIg course. Twenty patients received an ‘early’ second IVIg course (1–2 weeks after start of the first IVIg course) and 18 patients a ‘late’ second IVIg course (2–4 weeks after start of IVIg). At baseline and 1 week, those receiving two IVIg courses were more disabled than those receiving one course. Compared with the one course group, the adjusted OR for a better GBS disability score at 4 weeks was 0.70 (95%CI 0.16 to 3.04) for the early group and 0.66 (95%CI 0.18 to 2.50) for the late group. The secondary endpoints were not in favour of a second IVIg course.ConclusionsThis observational study did not show better outcomes after a second IVIg course in GBS with poor prognosis. The study was limited by small numbers and baseline imbalances. Lack of improvement was likely an incentive to start a second IVIg course. A prospective randomised trial is needed to evaluate whether a second IVIg course improves outcome in GBS.
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- 2019
12. Using fallout plutonium as a probe for erosion assessment
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Hoo, W.T., Fifield, L.K., Tims, S.G., Fujioka, T., and Mueller, N.
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- 2011
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13. 7.5kA High-Tc Superconducting Current Lead
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Masegi, T., Kimura, S., Yamada, Y., Fujioka, T., Yamafuji, Kaoru, editor, and Morishita, Tadataka, editor
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- 1995
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14. Effect of The Void-Fraction on the Property of the Nb3Sn Cable-in-Conduit Conductor
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Nishi, M., Yamamoto, K., Sasaki, T., Wadayama, Y., Miyake, A., Hanawa, H., Takaya, Y., Tsuji, H., Ono, M., Wachi, Y., Hanawa, S., Shimada, M., Hamajima, T., Takano, T., Fujioka, T., Reed, Richard P., editor, Fickett, Fred R., editor, Summers, Leonard T., editor, and Stieg, M., editor
- Published
- 1994
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15. Nutrient recovery and microalgae biomass production from urine by membrane photobioreactor at low biomass retention times
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Nguyen, TT, Bui, XT, Ngo, HH, Nguyen, TTD, Nguyen, KQ, Nguyen, HH, Huynh, KPH, Némery, J, Fujioka, T, Duong, CH, Dang, BT, and Varjani, S
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Environmental Sciences - Abstract
Urine has been considered as an ideal nutrient source for microalgae cultivation thanks to its composition containing the high concentrations of nitrogen and phosphorus. Herein, the microalgae growth in urine was evaluated in a lab-scale membrane photobioreactor (MPBR) system. This work aimed to validate the influence of low biomass retention times (BRT) (10, 7, 5, 3, 2 d) on nutrient remediation and biomass productivity. It revealed that BRT of 7 d resulted in synergistically high biomass production (biomass productivity of 313 mg/L.d) and removal rates (TN of 90.5 mg/L.d and TP of 4.7 mg/L.d). Notably, the short BRT of 2–5 d was not sufficient to trigger actively growing microalgae and thus reduced biomass production rate. In addition, as operated at a low flux of 2 L/m2.h, MPBR system required no physical cleaning for 100 days of operation. The BRT-dependent biomass concentration played a pivotal role in changing the fouling rate of MPBR; however, the fouling is reversible in the MPBR system under the low flux condition.
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- 2021
16. Fouling behavior and performance of a submerged flat-sheet nanofiltration membrane system for direct treatment of secondary wastewater effluent
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Ngo, MTT, Ueyama, T, Makabe, R, Bui, XT, Nghiem, LD, Nga, TTV, and Fujioka, T
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0905 Civil Engineering, 0907 Environmental Engineering - Abstract
Direct nanofiltration (NF) of secondary treated effluent can significantly simplify water recycling, especially for small scale operations. This study evaluated the performance of a novel flat-sheet submerged NF membrane module at low water flux to minimize membrane fouling. The separation performance of the NF system was assessed by periodically measuring the color, turbidity, pH, UV light absorbance at the wavelength of 254 nm, and total organic carbon concentrations of the NF feed water and permeate. During the 48-d test, negligible membrane fouling was found when direct NF treatment of secondary wastewater effluent was conducted at a water flux of 3 L/m2h. The trans-membrane pressure increased by less than 0.072 kPa/d. The foulant layer on the membrane surface was readily removed by simple physical cleaning, which suggests that the reversible fouling was the major fouling mechanism. Direct NF treatment achieved high and stable removal of organics (total organic carbon removal of >80 %) during the operation period. This study demonstrated the efficacy of the direct NF treatment using a submerged NF module for achieving stable operations and producing high-quality recycled water.
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- 2021
17. Primary Design of 40 Tesla Class Hybrid Magnet System
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Inoue, K., Takeuchi, T., Kiyoshi, T., Itoh, K., Wada, H., Maeda, H., Nii, K., Fujioka, T., Sumiyoshi, Y., Hanai, S., Hamajima, T., Sekiguchi, T., editor, and Shimamoto, S., editor
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- 1990
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18. Development of kA-Class Superconducting Cables for AC Use (II) Electromagnetic Properties
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Funaki, K., Tasaki, K., Iwakuma, M., Takeo, M., Yamafuji, K., Hamajima, T., Shimada, M., Ono, M., Yamaguchi, M., Itoh, D., Fujioka, T., Kumano, T., Suzuki, H., Sekiguchi, T., editor, and Shimamoto, S., editor
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- 1990
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19. Development of Ka-Class Superconducting Cables for AC Use (I)-Design and Fabrication
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Hamajima, T., Shimada, M., Ono, M., Yamaguchi, M., Itoh, D., Fujioka, T., Funaki, K., Tasaki, K., Iwakuma, M., Takeo, M., Yamafuji, K., Kumano, T., Suzuki, E., Sekiguchi, T., editor, and Shimamoto, S., editor
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- 1990
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20. Intravenous immunoglobulin treatment for mild Guillain-Barré syndrome. An international observational study
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Verboon, C., Harbo, T., Cornblath, D. R., Hughes, R. A. C., Van Doorn, P. A., Lunn, M. P., Gorson, K. C., Barroso, F., Kuwabara, S., Galassi, G., Lehmann, H. C., Kusunoki, S., Reisin, R. C., Binda, D., Cavaletti, G., Andersen, Jacobs B. C. H., PhD (Aarhus University Hospital, Aarhus, Denmark), Attarian, S., PhD (CHU Timone, Marseille, France), Badrising, U. A., PhD (Leiden University Medical Centre, Leiden, The, Netherlands), Bateman, K., PhD (Groote Schuur Hospital, Cape, Town, South-Africa), Benedetti, L., PhD (Ospedale Sant’ Andrea La Spezia, Spezia, La, Italy), van den Berg, B., MD (Franciscus Gasthuis, Rotterdam, Van den Bergh, P., Luc, PhD (University Clinic St., Leuven, Belgium), Bertorini, T. E., MD (The University of Tennessee Health Science Center (UTHSC), Memphis, USA), Bhavaraju-Sanka, R., MD (University Hospital/ University of Texas Health Science Center, San Antonio Texas, USA), Bianco (Milan University, M., Humanitas Clinicala and Research Institute Milan, Briani, C., MD (University of Padova, Padova, Italy), Bürmann, J., MD (Universitätsklinikum des Saarlandes, Homburg, Germany), Casasnovas, C., Ciberer, PhD (Bellvitge University Hospital - IDIBELL Neurometabolic Diseases Group., Barcelona, Spain), Chao, C. C., PhD (National Taiwan University Hospital, Taipei, Taiwan), Chavada, G., PhD (Glasgow University, Glasgow, UK), Claeys, K. G., University Hospitals Leuven, PhD (1., Leuven, Belgium, KU Leuven, 2., Cosgrove, J. S., MD (Leeds General Infirmary, Leeds, UK), Dalakas, M. C., Thomas Jefferson University, MD (1., Philadelphia, Usa, National and Kapodistrian University of Athens, 2., Athens, Greece), Davidson, A., MD (University of Glasgow, van Dijk, G. W., MD (Canisius Wilhelmina Hospital, Nijmegen, Dardiotis, E., MD (University of Thessaly, Hospital of Larissa, Larissa, Greece), Derejko, M., MD (Odense University Hospital, Odense, Denmark), Dimachkie, M. M., MD (University of Kansas Medical Center, Kansas, City, Dornonville de la Cour, C., MD (National Hospital Copenhagen, Copenhagen, Denmark), Echaniz-Laguna, A., MD (Bicêtre University Hospital, Paris, France), Eftimov, F., PhD (Amsterdam University Medical Centre, Amsterdam, Faber, C. G., PhD (Maastricht University Medical Centre, Maastricht, Fazio, R., MD (Scientific Institute San Raffaele, Milan, Italy), Fulgenzi, J. Fehmi (University of Oxford E. A., MD (Hospital Cesar Milstein Buenos Aires, Buenos, Aires, Argentina), García-Sobrino, T., MD (Hospital Clínico de Santiago, Santiago de Compostela (A Coruña), Spain), Gijsbers, C. J., MD (Vlietland Hospital, Schiedam, Granit, V., MD (Montefiore Medical, Center, New, York, Grisanti, S., MD (Ospedale Sant’ Andrea La Spezia, Gutiérrez-Gutiérrez, G., MD (Hospital Universitario Infanta Sofia, San, Sebastian, Holbech, J. V., PhD (Odense University Hospital, Holt, J. K. L., Phd, FRCP (The Walton Centre, Liverpool, UK), Homedes, C., Ciberer, MD (Bellvitge University Hospital - IDIBELL Neurometabolic Diseases Group., Islam, B., PhD (International Centre for Diarrhoeal Disease Research, Bangladesh, (icddr, Dhaka, b), Bangladesh), Islam, Z., Jahan, I., PhD candidate (International Centre for Diarrhoeal Disease Research, Jericó Pascual, I., PhD (Complejo Hospitalario de Navarra, Pamplona, Spain), Karafiath, S., MD (University of Utah School of Medicine, Salt Lake City, Kerkhoff, H., PhD (Albert Schweitzer Hospital, Dordrecht, Kimpinski, K., MD (University Hospital, Lhsc, London-Ontario, Canada), Kohler, A., MD (Instituto de Investigaciones Neurológicas Raúl Carrea, Fleni, Kolb, N., MD (University of Vermont, Burlington, Vt, Kuitwaard, K., Albert Schweitzer Hospital, PhD (1., Erasmus MC, 2., Kuwahara, M., PhD (Kindai University, Osaka, Japan), Ladha, S. S., MD (Barrow Neurology Clinics, Phoenix, Arizona, Lee Pan, E., MBChB (Groote Schuur Hospital, Marfia, G. A., MD (Neurological Clinic, Policlinico Tor Vergata, Rome, Italy), Magot, A., MD (Reference Centre for NMD, Nantes University Hospital, France), Márquez Infante, C., MD (Hospital Universitario Virgen del Rocio, Seville, Spain), Martín-Aguilar, L., MD (Hospital de la Santa Creu, i Sant Pau, Universitat Autònoma de Barcelona, Martinez Hernandez, E., MD (Institut d’Investigacions Biomèdiques August Pi, i Sunyer (IDIBAPS), Hospital, Clinic, Mataluni, G., PhD (Neurological Clinic, Meekins, G., MD (University of Minnesota, Miller, J. A. L., PhD (Royal Victoria Infirmary, Newcastle, UK), Monges, M. S., Garrahan, MD (Hospital de Pediatría J. P., Nobile Orazio, E., PhD (Milan University, Pardal, A., MD (Hospital Britanico, Pardo Fernandez (Hospital Clínico de Santiago, J., Péréon, Y., PhD (Reference Centre for NMD, Pulley, M., MD (University of Florida, Jacksonville, USA), Querol Gutierrez, L., PhD (Hospital de la Santa Creu, i Sant Pau, Reddel, S. W., PhD (Concord Repatriation General Hospital, Sydney, Australia), van der Ree, T., (Westfriesgasthuis, Md, Hoorn, Rinaldi, S., Mbchb, Samijn, PhD (University of Oxford J. P. A., MD (Maasstad Hospital, Samukawa, M., Santoro, L., PhD (University Federico II, Napels, Italy), Savransky, A., Garrahan, PhD (Hospital de Pediatría J. P., Schwindling, L., Sedano Tous, M. J., MD (Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Sekiguchi, Y., PhD (Chiba University, Chiba, Japan), Shahrizaila, N., MD (Neurology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Malaya), Silvestri, N. J., Sindrup, MD (Buffalo Jacobs School of Medicine S., Sommer, C. L., MD (Universitätsklinikum Würzburg, Würzburg, Germany), Spyropoulos (Royal Victoria Infirmary, A., Stein, B., Joseph’s Regional Medical Center, MD (St., Paterson, USA), Tan, C. Y., MRCP (Neurology Unit, Tankisi, H., Vermeij, F., Vytopil, M. V., Wirtz, PhD (Tufts University School of Medicine Lahey Hospital P. W., Phd, (HagaZiekenhuis, The, Hague, Waheed, W., MD (University of Vermont Medical Center, Burlington, Addington, USA). Other collaborators were:J. M., MD (University of Virginia, Charlottesville, USA), Ajroud-Driss, S., MD (Northwestern University Feinberg, Chicago, USA), Antonini, G., MD (Mental Health and Sensory Organs (NESMOS), Sapienza, University, Sant’Andrea, Hospital, Bella, I. R., MD (University of Mass Medical School, Worcester, USA), Brannagan, T. H., MD (Columbia University, New York City, Bunschoten, C., PhD candidate (Erasmus University Medical Centre, Busby, M., Bradford, UK), Butterworth, S., MD (Pinderfields Hospital, Wakefield, UK), Conti, M. E., MD (University Hospital Clinicas, Chen, S., Phd, (Rutgers, Robert Wood Johnson University Hospital, New, Brunswick, Doets, A., Feasby, T. E., MD (University of Calgary, Calgary, Canada), Fokke, C., MD (Gelre Hospital, Zutphen and Apeldoorn, Fujioka, T., MD (Toho University Medical Center, Tokyo, Japan), Garssen, M. P. J., PhD (Jeroen Bosch Hospital, Hertogenbosch, ’S, Gilchrist, J. M., MD (Soulthern Illinois University School of Medicine, Springfield, USA), Gilhuis, J., PhD (Reinier de Graaf Gasthuis, Delft, Goldstein, J. M., MD (Yale University School of Medicine, New, Haven, Goyal, N. A., MD (University of California, Irvine, USA), Hadden, R. D. M., PhD (King’s College Hospital, London, UK), Hsieh, S. T., Htut, M., George’s Hospital, MD (St., Illa, I., Jellema, K., PhD (Haaglanden Medisch Centrum, Kaida, K., PhD (National Defense Medical College, Saitama, Japan), Katzberg, H. D., MD (University of Toronto, Toronto, Canada), Kiers, L., MD (University of Melbourne, Royal Melbourne Hospital, Parkville, Australia), Kokubun, N., MD (Dokkyo Medical University, Tochigi, Japan), van Koningsveld, R., PhD (Elkerliek Hospital, Helmond and Deurne, van der Kooi, A. J., Kwan, J. Y., MD (University of Maryland School of Medicine, Baltimore, USA), Landschoff Lassen, L., MD (Glostrup Hospital, Glostrup, Denmark), Lawson, V., MD (Wexner Medical Center at The Ohio State University, Columbus, USA), Leonhard, S. E., Mandarakas, M., PhD (Erasmus University Medical Centre, Manji, H., FRCP (Ipswich Hospital, Ipswich, UK), Mattiazzi, M. G., MD (Hospital Militar Central, Mcdermott, C. J., MD (Royal Hallamshire Hospital, Nihr, Clinical, Sheffield, UK), Mohammad, Q. D., PhD (National Institute of Neurosciences and Hospital, Dhaka, Bangladesh), Morís de la Tassa, G., MD (Hospital UniversitarioCentral de Asturias, Asturias, Spain), Nascimbene, C., PhD (Luigi Sacco Hospital, Niks, E. H., Nowak, R. J., Osei-Bonsu, M., PhD (James Cook University Hospital, Middlesbrough, UK), Pascuzzi, R. M., MD (University of Indiana School of Medicine, Indianapolis, USA), Roberts, R. C., MD (Addenbrooke’s Hospital Cambridge, Cambridge, UK), Rojas-Marcos, I., MD (Hospital Univesitario Reina Sofia, Cordoba, Spain), Roodbol, J., Rudnicki, S. A., MD (University of Arkansas, Fayetteville, USA), Sachs, G. M., MD (University of Rhode Island, Providence, USA), Schenone, A., Department of Neurosciences, PhD (1., Rehabilitation, Ophthalmology, Genetics and Maternal and Infantile Sciences (DINOGMI), University of Genova, Genova, IRCCS Policlinico San Martino, Italy 2., Genova, Italy), Sheikh, K., PhD (The University of Texas Health Science Center at Houston, Houston, USA), Twydell, P., DO (Spectrum Health System, Grand, Rapids, Van Damme, P., PhD (University Hospital Leuven, Varrato, J. D., DO (Lehigh Valley Health Network, Allentown, USA), Visser, L. H., PhD (Elisabeth-TweeSteden Hospital, Tilburg and Waalwijk, Willison, H. J., PhD (University of Glasgow, van Woerkom (Erasmus MC, M., Zhou, L., PhD (Icahn School, Verboon, C, Harbo, T, Cornblath, D, Hughes, R, Van Doorn, P, Lunn, M, Gorson, K, Barroso, F, Kuwabara, S, Galassi, G, Lehmann, H, Kusunoki, S, Reisin, R, Binda, D, Cavaletti, G, Jacobs, B, consortium, IGOS, consortium, GOS, Neurosurgery, Neurology, and Immunology
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Adult ,Male ,medicine.medical_specialty ,intravenous immunoglobulins ,DIAGNOSIS ,Guillain-Barre Syndrome ,Settore MED/26 ,DISEASE ,Disease course ,Disability Evaluation ,03 medical and health sciences ,0302 clinical medicine ,SDG 3 - Good Health and Well-being ,hemic and lymphatic diseases ,Internal medicine ,Clinical endpoint ,medicine ,Humans ,In patient ,guillain-barré syndrome ,030212 general & internal medicine ,NEUROPATHIES ,biology ,Guillain-Barre syndrome ,business.industry ,Guillain-Barré syndrome (GBS), treatment, course ,Confounding ,Immunoglobulins, Intravenous ,Middle Aged ,medicine.disease ,Confidence interval ,Psychiatry and Mental health ,Treatment Outcome ,biology.protein ,Female ,Surgery ,Observational study ,Neurology (clinical) ,Antibody ,business ,030217 neurology & neurosurgery - Abstract
ObjectiveTo compare the disease course in patients with mild Guillain-Barré syndrome (GBS) who were treated with intravenous immunoglobulin (IVIg) or supportive care only.MethodsWe selected patients from the prospective observational International GBS Outcome Study (IGOS) who were able to walk independently at study entry (mild GBS), treated with one IVIg course or supportive care. The primary endpoint was the GBS disability score four weeks after study entry, assessed by multivariable ordinal regression analysis.ResultsOf 188 eligible patients, 148 (79%) were treated with IVIg and 40 (21%) with supportive care. The IVIg group was more disabled at baseline. IVIg treatment was not associated with lower GBS disability scores at 4 weeks (adjusted OR (aOR) 1.62, 95% CI 0.63 to 4.13). Nearly all secondary endpoints showed no benefit from IVIg, although the time to regain full muscle strength was shorter (28 vs 56 days, p=0.03) and reported pain at 26 weeks was lower (n=26/121, 22% vs n=12/30, 40%, p=0.04) in the IVIg treated patients. In the subanalysis with persistent mild GBS in the first 2 weeks, the aOR for a lower GBS disability score at 4 weeks was 2.32 (95% CI 0.76 to 7.13). At 1 year, 40% of all patients had residual symptoms.ConclusionIn patients with mild GBS, one course of IVIg did not improve the overall disease course. The certainty of this conclusion is limited by confounding factors, selection bias and wide confidence limits. Residual symptoms were often present after one year, indicating the need for better treatments in mild GBS.
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- 2021
21. Frequency of CD4+FOXP3+ regulatory T-cells at early stages after HLA-mismatched allogeneic hematopoietic SCT predicts the incidence of acute GVHD
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Fujioka, T, Tamaki, H, Ikegame, K, Yoshihara, S, Taniguchi, K, Kaida, K, Kato, R, Inoue, T, Nakata, J, Ishii, S, Soma, T, Okada, M, and Ogawa, H
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- 2013
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22. Donor-derived HLA antibody production in patients undergoing SCT from HLA antibody-positive donors
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Taniguchi, K, Yoshihara, S, Maruya, E, Ikegame, K, Kaida, K, Hayashi, K, Kato, R, Inoue, T, Fujioka, T, Tamaki, H, Okada, M, Onuma, T, Fujii, N, Kusunoki, Y, Soma, T, Saji, H, and Ogawa, H
- Published
- 2012
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23. Incidence of extramedullary relapse after haploidentical SCT for advanced AML/myelodysplastic syndrome
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Yoshihara, S, Ikegame, K, Kaida, K, Taniguchi, K, Kato, R, Inoue, T, Fujioka, T, Tamaki, H, Okada, M, Soma, T, and Ogawa, H
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- 2012
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24. Risk and prevention of graft failure in patients with preexisting donor-specific HLA antibodies undergoing unmanipulated haploidentical SCT
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Yoshihara, S, Maruya, E, Taniguchi, K, Kaida, K, Kato, R, Inoue, T, Fujioka, T, Tamaki, H, Ikegame, K, Okada, M, Soma, T, Hayashi, K, Fujii, N, Onuma, T, Kusunoki, Y, Saji, H, and Ogawa, H
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- 2012
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25. Salvage haploidentical transplantation for graft failure using reduced-intensity conditioning
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Yoshihara, S, Ikegame, K, Taniguchi, K, Kaida, K, Kim, E H, Nakata, J, Kato, R, Inoue, T, Fujioka, T, Tamaki, H, Okada, M, Soma, T, and Ogawa, H
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- 2012
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26. Intralymph Nodal Injection of The Mixture of OK-432 and Mitomycin C (MMC) Adsorbed onto Fine Activated Carbon Particles (CH40) for the Treatment of Lymph Node Metastasis
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Okano, S., Sawai, K., Minato, H., Fujioka, T., Yamaguchi, M., Kanemitsu, K., Hagiwara, A., Takahashi, T., and Takahashi, Toshio, editor
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- 1993
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27. Clinical relevance of cagPAI intactness in Helicobacter pylori isolates from Vietnam
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Nguyen, L. T., Uchida, T., Tsukamoto, Y., Trinh, T. D., Ta, L., Mai, H. B., Le, H. S., Ho, D. Q. D., Hoang, H. H., Matsuhisa, T., Okimoto, T., Kodama, M., Murakami, K., Fujioka, T., Yamaoka, Y., and Moriyama, M.
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- 2010
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28. International Guillain-Barré Syndrome Outcome Study
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Jacobs, B, van den Berg, B, Verboon, C, Chavada, G, Cornblath, D, Gorson, K, Harbo, T, Hartung, H, Hughes, R, Kusunoki, S, van Doorn, P, Willison, H, Consortium, I, van Woerkom, M, Roodbol, J, Reisin, R, Reddel, S, Islam, Z, Islam, B, Mohammad, Q, van den Bergh, P, Feasby, T, Wang, Y, Péréon, Y, Lehmann, H, Dardiotis, E, Nobile Orazio, E, Shahrizaila, N, Bateman, K, Illa, I, Querol, L, Hsieh, S, Davidson, A, Addington, J, Ajroud Driss, S, Andersen, H, Antonini, G, Attarian, S, Badrising, U, Barroso, F, Benedetti, L, Beronio, A, Bianco, M, Binda, D, Briani, C, Bürmann, J, Bella, I, Bertorini, T, Bhavaraju Sanka, R, Brannagan, T, Busby, M, Butterworth, S, Campagnolo, M, Casasnovas, C, Cavaletti, G, Chao, C, Chen, S, Chetty, S, Claeys, K, Cohen, J, Conti, M, Cosgrove, J, Dalakas, M, Dimachkie, M, Dillmann, U, Domínguez González, C, Doppler, K, Dornonville de la Cour, C, Echaniz Laguna, A, Eftimov, F, Faber, C, Fazio, R, Fokke, C, Fujioka, T, Fulgenzi, E, Galassi, G, Garcia, T, Garnero, M, Garssen, M, Gijsbers, C, Gilchrist, J, Gilhuis, H, Goldstein, J, Goyal, N, Granit, V, Grapperon, A, Gutiérrez Gutiérrez, G, Gutmann, L, Hadden, R, Holbech, J, Holt, J, Homedes Pedret, C, Htut, M, Jellema, K, Jericó Pascual, I, Kaida, K, Karafiath, S, Katzberg, H, Kiers, L, Kieseier, B, Kimpinski, K, Kleyweg, R, Kokubun, N, Kolb, N, Kuitwaard, K, Kuwabara, S, Kwan, J, Ladha, S, Landschoff Lassen, L, Lawson, V, Ledingham, D, Léon Cejas, L, Luciano, C, Lucy, S, Lunn, M, Magot, A, Manji, H, Marchesoni, C, Marfia, Ga, Márquez Infante, C, Martinez Hernandez, E, Mataluni, G, Mattiazi, M, Mcdermott, C, Meekins, G, Miller, J, Monges, M, Montero, M, Morís de la Tassa, G, Nascimbene, C, Neumann, C, Nowak, R, Orizaola Balaguer, P, Osei Bonsu, M, Pan, E, Pardo Fernandez, J, Pasnoor, M, Pulley, M, Rajabally, Y, Rinaldi, S, Ritter, C, Roberts, R, Rojas Marcos, I, Rudnicki, S, Sachs, G, Samijn, J, Santoro, L, Saperstein, D, Savransky, A, Schneider, H, Schenone, A, Sedano Tous, M, Sekiguchi, Y, Sheikh, K, Silvestri, N, Sindrup, S, Sommer, C, Stein, B, Stino, A, Spyropoulos, A, Srinivasan, J, Suzuki, H, Taylor, S, Tankisi, H, Tigner, D, Twydell, P, Valzania, F, van Damme, P, van der Kooi, A, van Dijk, G, van der Ree, T, van Koningsveld, R, Varrato, J, Vermeij, F, Verschuuren, J, Visser, L, Vytopil, M, Waheed, W, Wilken, M, Wilkerson, C, Wirtz, P, Yamagishi, Y, Yiu, E, Zhou, L, Zivkovic, S, Immunology, Neurology, Jacobs, B, van den Berg, B, Verboon, C, Chavada, G, Cornblath, D, Gorson, K, Harbo, T, Hartung, H, Hughes, R, Kusunoki, S, van Doorn, P, Willison, H, van Woerkom, M, Roodbol, J, Reisin, R, Reddel, S, Islam, Z, Islam, B, Mohammad, Q, van den Bergh, P, Feasby, T, Wang, Y, Pã©rã©on, Y, Lehmann, H, Dardiotis, E, Nobile Orazio, E, Shahrizaila, N, Bateman, K, Illa, I, Querol, L, Hsieh, S, Davidson, A, Addington, J, Ajroud Driss, S, Andersen, H, Antonini, G, Attarian, S, Badrising, U, Barroso, F, Benedetti, L, Beronio, A, Bianco, M, Binda, D, Briani, C, Bã¼rmann, J, Bella, I, Bertorini, T, Bhavaraju Sanka, R, Brannagan, T, Busby, M, Butterworth, S, Campagnolo, M, Casasnovas, C, Cavaletti, G, Chao, C, Chen, S, Chetty, S, Claeys, K, Cohen, J, Conti, M, Cosgrove, J, Dalakas, M, Dimachkie, M, Dillmann, U, DomÃnguez González, C, Doppler, K, Dornonville de la Cour, C, Echaniz Laguna, A, Eftimov, F, Faber, C, Fazio, R, Fokke, C, Fujioka, T, Fulgenzi, E, Galassi, G, Garcia, T, Garnero, M, Garssen, M, Gijsbers, C, Gilchrist, J, Gilhuis, H, Goldstein, J, Goyal, N, Granit, V, Grapperon, A, Gutiérrez Gutiérrez, G, Gutmann, L, Hadden, R, Holbech, J, Holt, J, Homedes Pedret, C, Htut, M, Jellema, K, Jericó Pascual, I, Kaida, K, Karafiath, S, Katzberg, H, Kiers, L, Kieseier, B, Kimpinski, K, Kleyweg, R, Kokubun, N, Kolb, N, Kuitwaard, K, Kuwabara, S, Kwan, J, Ladha, S, Landschoff Lassen, L, Lawson, V, Ledingham, D, Léon Cejas, L, Luciano, C, Lucy, S, Lunn, M, Magot, A, Manji, H, Marchesoni, C, Marfia, G, Márquez Infante, C, Martinez Hernandez, E, Mataluni, G, Mattiazi, M, Mcdermott, C, Meekins, G, Miller, J, Monges, M, Montero, M, MorÃs de la Tassa, G, Nascimbene, C, Neumann, C, Nowak, R, Orizaola Balaguer, P, Osei Bonsu, M, Pan, E, Pardo Fernandez, J, Pasnoor, M, Pulley, M, Rajabally, Y, Rinaldi, S, Ritter, C, Roberts, R, Rojas Marcos, I, Rudnicki, S, Sachs, G, Samijn, J, Santoro, L, Saperstein, D, Savransky, A, Schneider, H, Schenone, A, Sedano Tous, M, Sekiguchi, Y, Sheikh, K, Silvestri, N, Sindrup, S, Sommer, C, Stein, B, Stino, A, Spyropoulos, A, Srinivasan, J, Suzuki, H, Taylor, S, Tankisi, H, Tigner, D, Twydell, P, Valzania, F, van Damme, P, van der Kooi, A, van Dijk, G, van der Ree, T, van Koningsveld, R, Varrato, J, Vermeij, F, Verschuuren, J, Visser, L, Vytopil, M, Waheed, W, Wilken, M, Wilkerson, C, Wirtz, P, Yamagishi, Y, Yiu, E, Zhou, L, Zivkovic, S, Rehabilitation medicine, Internal medicine, and ANS - Neuroinfection & -inflammation
- Subjects
Male ,Pediatrics ,PROGNOSIS ,diagnosis ,International Cooperation ,Guillain-Barré syndrome ,biomarkers ,outcome ,prognosis ,treatment ,Guillain-Barre syndrome ,Guillain-Barré syndrome ,Neuroscience (all) ,Neurology (clinical) ,Cohort Studies ,0302 clinical medicine ,Epidemiology ,Outcome Assessment, Health Care ,INFECTION ,CRITERIA ,030212 general & internal medicine ,General Neuroscience ,Biobank ,Observational Studies as Topic ,diagnosi ,Disease Progression ,biomarker ,Female ,Settore MED/26 - Neurologia ,medicine.symptom ,prognosi ,Cohort study ,medicine.medical_specialty ,Weakness ,Guillain-Barre Syndrome ,CLASSIFICATION ,VALIDATION ,03 medical and health sciences ,medicine ,Humans ,INTRAVENOUS IMMUNOGLOBULIN ,Protocol (science) ,business.industry ,Polyradiculoneuropathy ,medicine.disease ,ANTIBODIES ,Observational study ,business ,COLLECTION ,030217 neurology & neurosurgery - Abstract
Guillain-Barré syndrome (GBS) is an acute polyradiculoneuropathy with a highly variable clinical presentation, course, and outcome. The factors that determine the clinical variation of GBS are poorly understood which complicates the care and treatment of individual patients. The protocol of the ongoing International GBS Outcome Study (IGOS), a prospective, observational, multicenter cohort study that aims to identify the clinical and biological determinants and predictors of disease onset, subtype, course and outcome of GBS is presented here. Patients fulfilling the diagnostic criteria for GBS, regardless of age, disease severity, variant forms, or treatment, can participate if included within 2 weeks after onset of weakness. Information about demography, preceding infections, clinical features, diagnostic findings, treatment, course, and outcome is collected. In addition, cerebrospinal fluid and serial blood samples for serum and DNA is collected at standard time points. The original aim was to include at least 1,000 patients with a follow-up of 1-3 years. Data are collected via a web-based data entry system and stored anonymously. IGOS started in May 2012 and by January 2017 included more than 1,400 participants from 143 active centers in 19 countries across 5 continents. The IGOS data/biobank is available for research projects conducted by expertise groups focusing on specific topics including epidemiology, diagnostic criteria, clinimetrics, electrophysiology, antecedent events, antibodies, genetics, prognostic modeling, treatment effects, and long-term outcome of GBS. The IGOS will help to standardize the international collection of data and biosamples for future research of GBS.
- Published
- 2017
29. CD133 is a positive marker for a distinct class of primitive human cord blood-derived CD34-negative hematopoietic stem cells
- Author
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Takahashi, M, Matsuoka, Y, Sumide, K, Nakatsuka, R, Fujioka, T, Kohno, H, Sasaki, Y, Matsui, K, Asano, H, Kaneko, K, and Sonoda, Y
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- 2014
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- View/download PDF
30. Flexible laser diode trace gas sensor based on cavity ringdown spectroscopy with an optical fiber-coupled high-finesse external-cavity diode laser
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Sato, J., Kikukawa, M., Yamaguchi, S., Endo, M., Tei, K., Nanri, K., and Fujioka, T.
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- 2009
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31. Overexpressing PKIB in prostate cancer promotes its aggressiveness by linking between PKA and Akt pathways
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Chung, S, Furihata, M, Tamura, K, Uemura, M, Daigo, Y, Nasu, Y, Miki, T, Shuin, T, Fujioka, T, Nakamura, Y, and Nakagawa, H
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- 2009
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32. Current treatment practice of Guillain-Barré syndrome
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Verboon C., Doets A. Y., Galassi G., Davidson A., Waheed W., Pereon Y., Shahrizaila N., Kusunoki S., Lehmann H. C., Harbo T., Monges S., Van Den Bergh P., Willison H. J., Cornblath D. R., Jacobs B. C., Hughes R. A. C., Gorson K. C., Hartung H. P., Van Doorn P. A., Van den Berg B., Roodbol J., Van Woerkom M., Reisin R. C., Reddel S. W., Islam Z., Islam B., Mohammad Q. D., Feasby T. E., Dardiotis E., Nobile-Orazio E., Bateman K., Illa I., Querol L., Hsieh S. T., Chavada G., Addington J. M., Ajroud-Driss S., Andersen H., Antonini G., Ariatti A., Attarian S., Badrising U. A., Barroso F. A., Benedetti L., Beronio A., Bianco M., Binda D., Briani C., Bunschoten C., Burmann J., Bella I. R., Bertorini T. E., Bhavaraju-Sanka R., Brannagan T. H., Busby M., Butterworth S., Casasnovas C., Cavaletti G., Chao C. C., Chen S., Chetty S., Claeys K. G., Conti M. E., Cosgrove J. S., Dalakas MC., Demichelis C., Derejko M. A., Dillmann U., Dimachkie M. M., Doppler K., Dornonville de la Cour C., Echaniz-Laguna A., Eftimov F., Faber C. G., Fazio R., Fokke C., Fujioka T., Fulgenzi E. A., Garcia-Sobrino T., Garssen M. P. J., Georgios H. M., Gijsbers C. J., Gilchrist J. M., Gilhuis J., Giorli E., Goldstein J. M., Goyal N. A., Granit V., Grapperon A., Gutierrez G., Hadden R. D. M., Holbech J. V., Holt J. K. L., Pedret C. H., Htut M., Jellema K., Pascual I. J., Jimeno-Montero M. C., Kaida K., Karafiath S., Katzberg H. D., Kiers L., Kieseier B. C., Kimpinski K., Kleyweg R. P., Kokubun N., Kolb N. A., Kuitwaard K., Kuwabara S., Kwan J. Y., Ladha S. S., Lassen L. L., Lawson V., Ledingham D., Lucy S. T., Lunn M. P. T., Magot A., Manji H., Marchesoni C., Marfia G. A., Infante C. M., Hernandez E. M., Mataluni G., Mattiazi M., McDermott C. J., Meekins G. D., Miller J. A. L., Moris de la Tassa G., Physiotherapist J. M., Nascimbene C., Nowak R. J., Balaguer P. O., Osei-Bonsu M., Pan E. B. L., Pardal A. M., Pardo J., Pasnoor M., Pulley M., Rajabally Y. A., Rinaldi S., Ritter C., Roberts R. C., Rojas-Marcos I., Rudnicki S. A., Ruiz M., Sachs G. M., Samijn J. P. A., Santoro L., Savransky A., Schenone A., Schwindling L., Tous M. J. S., Sekiguchi Y., Sheikh K. A., Silvestri N. J., Sindrup S. H., Sommer C. L., Stein B., Stino A. M., Spyropoulos A., Srinivasan J., Styliani R., Suzuki H., Tankisi H., Tigner D., Twydell P., Van Damme P., Van der Kooi A. J., Van Dijk G. W., Van der Ree T., Van Koningsveld R., Valzania F., Varrato J. D., Vermeij F. H., Verschuuren J., Visser L. H., Vytopil M. V., Wilken M., Wilkerson C., Wirtz P. W., Yamagishi Y., Zhou L., Zivkovic S. A., Neurology, AII - Infectious diseases, AII - Inflammatory diseases, ANS - Neuroinfection & -inflammation, Immunology, Erasmus MC other, UCL - SSS/IONS/NEUR - Clinical Neuroscience, UCL - (SLuc) Service de neurologie, Verboon, C, Doets, A, Galassi, G, Davidson, A, Waheed, W, Pereon, Y, Shahrizaila, N, Kusunoki, S, Lehmann, H, Harbo, T, Monges, S, Van Den Bergh, P, Willison, H, Cornblath, D, Jacobs, B, Hughes, R, Gorson, K, Hartung, H, Van Doorn, P, Van den Berg, B, Roodbol, J, Van Woerkom, M, Reisin, R, Reddel, S, Islam, Z, Islam, B, Mohammad, Q, Feasby, T, Dardiotis, E, Nobile-Orazio, E, Bateman, K, Illa, I, Querol, L, Hsieh, S, Chavada, G, Addington, J, Ajroud-Driss, S, Andersen, H, Antonini, G, Ariatti, A, Attarian, S, Badrising, U, Barroso, F, Benedetti, L, Beronio, A, Bianco, M, Binda, D, Briani, C, Bunschoten, C, Burmann, J, Bella, I, Bertorini, T, Bhavaraju-Sanka, R, Brannagan, T, Busby, M, Butterworth, S, Casasnovas, C, Cavaletti, G, Chao, C, Chen, S, Chetty, S, Claeys, K, Conti, M, Cosgrove, J, Dalakas, M, Demichelis, C, Derejko, M, Dillmann, U, Dimachkie, M, Doppler, K, Dornonville de la Cour, C, Echaniz-Laguna, A, Eftimov, F, Faber, C, Fazio, R, Fokke, C, Fujioka, T, Fulgenzi, E, Garcia-Sobrino, T, Garssen, M, Georgios, H, Gijsbers, C, Gilchrist, J, Gilhuis, J, Giorli, E, Goldstein, J, Goyal, N, Granit, V, Grapperon, A, Gutierrez, G, Hadden, R, Holbech, J, Holt, J, Pedret, C, Htut, M, Jellema, K, Pascual, I, Jimeno-Montero, M, Kaida, K, Karafiath, S, Katzberg, H, Kiers, L, Kieseier, B, Kimpinski, K, Kleyweg, R, Kokubun, N, Kolb, N, Kuitwaard, K, Kuwabara, S, Kwan, J, Ladha, S, Lassen, L, Lawson, V, Ledingham, D, Lucy, S, Lunn, M, Magot, A, Manji, H, Marchesoni, C, Marfia, G, Infante, C, Hernandez, E, Mataluni, G, Mattiazi, M, Mcdermott, C, Meekins, G, Miller, J, Moris de la Tassa, G, Physiotherapist, J, Nascimbene, C, Nowak, R, Balaguer, P, Osei-Bonsu, M, Pan, E, Pardal, A, Pardo, J, Pasnoor, M, Pulley, M, Rajabally, Y, Rinaldi, S, Ritter, C, Roberts, R, Rojas-Marcos, I, Rudnicki, S, Ruiz, M, Sachs, G, Samijn, J, Santoro, L, Savransky, A, Schenone, A, Schwindling, L, Tous, M, Sekiguchi, Y, Sheikh, K, Silvestri, N, Sindrup, S, Sommer, C, Stein, B, Stino, A, Spyropoulos, A, Srinivasan, J, Styliani, R, Suzuki, H, Tankisi, H, Tigner, D, Twydell, P, Van Damme, P, Van der Kooi, A, Van Dijk, G, Van der Ree, T, Van Koningsveld, R, Valzania, F, Varrato, J, Vermeij, F, Verschuuren, J, Visser, L, Vytopil, M, Wilken, M, Wilkerson, C, Wirtz, P, Yamagishi, Y, Zhou, L, and Zivkovic, S
- Subjects
Adult ,medicine.medical_specialty ,Adolescent ,Patient characteristics ,PLASMA-EXCHANGE ,030204 cardiovascular system & hematology ,Guillain-Barre Syndrome ,Settore MED/26 ,Severity of Illness Index ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Severity of illness ,Medicine ,Effective treatment ,INTRAVENOUS IMMUNOGLOBULIN ,Humans ,Prospective Studies ,Child ,Child, Preschool ,Treatment Outcome ,Prospective cohort study ,Preschool ,Guillain-Barre syndrome ,business.industry ,medicine.disease ,RANDOMIZED-TRIAL ,Prospective Studie ,Hospital treatment ,Treatment practice ,Observational study ,Neurology (clinical) ,business ,030217 neurology & neurosurgery ,Human - Abstract
ObjectiveTo define the current treatment practice of Guillain-Barré syndrome (GBS).MethodsThe study was based on prospective observational data from the first 1,300 patients included in the International GBS Outcome Study. We described the treatment practice of GBS in general, and for (1) severe forms (unable to walk independently), (2) no recovery after initial treatment, (3) treatment-related fluctuations, (4) mild forms (able to walk independently), and (5) variant forms including Miller Fisher syndrome, taking patient characteristics and hospital type into account.ResultsWe excluded 88 (7%) patients because of missing data, protocol violation, or alternative diagnosis. Patients from Bangladesh (n = 189, 15%) were described separately because 83% were not treated. IV immunoglobulin (IVIg), plasma exchange (PE), or other immunotherapy was provided in 941 (92%) of the remaining 1,023 patients, including patients with severe GBS (724/743, 97%), mild GBS (126/168, 75%), Miller Fisher syndrome (53/70, 76%), and other variants (33/40, 83%). Of 235 (32%) patients who did not improve after their initial treatment, 82 (35%) received a second immune modulatory treatment. A treatment-related fluctuation was observed in 53 (5%) of 1,023 patients, of whom 36 (68%) were re-treated with IVIg or PE.ConclusionsIn current practice, patients with mild and variant forms of GBS, or with treatment-related fluctuations and treatment failures, are frequently treated, even in absence of trial data to support this choice. The variability in treatment practice can be explained in part by the lack of evidence and guidelines for effective treatment in these situations.
- Published
- 2019
33. Involvement of upregulation of DEPDC1 (DEP domain containing 1) in bladder carcinogenesis
- Author
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Kanehira, M, Harada, Y, Takata, R, Shuin, T, Miki, T, Fujioka, T, Nakamura, Y, and Katagiri, T
- Published
- 2007
- Full Text
- View/download PDF
34. Second IVIg course in Guillain-Barré syndrome with poor prognosis. The non-randomised ISID study
- Author
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Verboon, C., Van Den Berg, B., Cornblath, D. R., Venema, E., Gorson, K. C., Lunn, M. P., Lingsma, H., Van Den Bergh, P., Harbo, T., Bateman, K., Pereon, Y., Sindrup, So. H., Kusunoki, S., Miller, J., Islam, Z., Hartung, H. -P., Chavada, G., Jacobs, B. C., Hughes, R. A. C., Addington, Van Doorn P. A. J. M., MD (University of Virginia, Charlottesville, USA), on October 7, S. Consortia. Protected by copyright., Downloaded from 8 Verboon C, 2019 at Uppsala Universitet BIBSAM http://jnnp. bmj. com/ J Neurol Neurosurg Psychiatry: first published as 10. 1136/jnnp-2019-321496 on 5 October 2019., J Neurol Neurosurg Psychiatry 2019, et al., 1136/jnnp-2019-321496 Neuromuscular Ajroud-Driss, 0:1–9. doi:10., MD (Northwestern University Feinberg, Chicago, USA), Antonini, G., MD (Mental Health and Sensory Organs (NESMOS), Sapienza, University, Sant’Andrea, Hospital, Rome, Italy), Attarian, S., PhD (CHU Timone, Marseille, France), Barroso, F. A., MD (Instituto de Investigaciones Neurológicas Raúl Carrea, Fleni, Buenos, Aires, Argentina), Benedetti, L., PhD (Ospedale Sant’ Andrea La Spezia, Spezia, La, Italy), Bertorini, T. E., MD (The University of Tennessee Health Science Center (UTHSC), Memphis, USA), Brannagan, T. H., MD (Columbia University, New York City, USA), Briani, C., MD (University of Padova, Padova, Italy), Bhavaraju-Sanka, R., MD (University Hospital/University of Texas Health Science Center, San Antonio Texas, Butterworth, S., MD (Pinderfields Hospital, Wakefield, UK), Casasnovas, C., Ciberer, PhD (Bellvitge University Hospital – IDIBELL Neurometabolic Diseases Group., Barcelona, Spain), Cavaletti, G., MD (University Milano-Bicocca, Monza, Italy), Chen, S., Phd, (Rutgers, Robert Wood Johnson University Hospital, New, Brunswick, Claeys, K. G., University Hospitals Leuven, PhD (1., Leuven, Belgium, KU Leuven, 2., Leuven, Belgium), Cosgrove, J. S., MD (Leeds General Infirmary, Leeds, UK), Davidson, A., MD (University of Glasgow, Glasgow, UK), Dardiotis, E., MD (University of Thessaly, Hospital of Larissa, Larissa, Greece), Dornonville de la Cour, C., MD (National Hospital Copenhagen, Copenhagen, Denmark), Faber, C. G., PhD (Maastricht University Medical Centre, Maastricht, The, Netherlands), Feasby, T. E., MD (University of Calgary, Calgary, Canada), Fujioka, T., MD (Toho University Medical Center, Tokyo, Japan), Galassi, G., MD (University Hospital of Modena, Modena, Italy), Gilchrist, J. M., MD (Soulthern Illinois University School of Medicine, Springfield, USA), Goyal, N. A., MD (University of California, Irvine, USA), Granit, V., MD (Montefiore Medical, Center, New, York, Gutiérrez-Gutiérrez, G., MD (Hospital Universitario Infanta Sofia, San, Sebastian, Spain), Hadden, R. D. M., PhD (King’s College Hospital, London, UK), Holt, J. K. L., Phd, FRCP (The Walton Centre, Liverpool, UK), Htut, M., George’s Hospital, MD (St., Jericó Pascual, I., PhD (Complejo Hospitalario de Navarra, Pamplona, Spain), Karafiath, S., MD (University of Utah School of Medicine, Salt Lake City, Katzberg, H. D., MD (University of Toronto, Toronto, Canada), Kiers, L., MD (University of Melbourne, Royal Melbourne Hospital, Parkville, Australia), Kieseier, B. C., MD (Heinrich Heine University, Düsseldorf, Germany), Kimpinski, K., MD (University Hospital, Lhsc, London-Ontario, Canada), Kuwabara, S., PhD (Chiba University, Chiba, Japan), Kwan, J. Y., MD (University of Maryland School of Medicine, Baltimore, USA), Ladha, S. S., MD (Barrow Neurology Clinics, Phoenix, Arizona, Lawson, V., MD (Wexner Medical Center at The Ohio State University, Columbus, USA), Lehmann, H., PhD (University Hospital of Cologne, Universitätsklinikum, Köln, Cologne, Germany), Manji, H., FRCP (Ipswich Hospital, Ipswich, UK), Marfia, G. A., MD (Neurological Clinic, Policlinico Tor Vergata, Márquez Infante, C., MD (Hospital Universitario Virgen del Rocio, Seville, Spain), Mattiazzi, M. G., MD (Hospital Militar Central, Mcdermott, C. J., MD (Royal Hallamshire Hospital, Nihr, Clinical, Sheffield, UK), Monges, M. S., Garrahan, MD (Hospital de Pediatría J. P., Morís de la Tassa, G., MD (Hospital Universitario Central de Asturias, Asturias, Spain), Nascimbene, C., PhD (Luigi Sacco Hospital, Milan, Italy), Nobile Orazio, E., PhD (Milan University, Humanitas Clinicala and Research Institute Milan, Nowak, R. J., MD (Yale University School of Medicine, New, Haven, Osei-Bonsu (James Cook University Hospital, M., Middlesbrough, UK), Pardo Fernandez (Hospital Clínico de Santiago, J., Santiago de Compostela (A Coruña), Querol Gutierrez, L., PhD (Hospital de la Santa Creu, i Sant Pau, Universitat Autònoma de Barcelona, Reisin (Hospital Britanico, R., Rinaldi, S., Mbchb, Roberts, PhD (University of Oxford R. C., MD (Addenbrooke’s Hospital Cambridge, Cambridge, UK), Rojas-Marcos, I., MD (Hospital Univesitario Reina Sofia, Cordoba, Spain), Rudnicki, S. A., MD (University of Arkansas, Fayetteville, USA), Schenone, A., Department of Neurosciences, PhD (1., Rehabilitation, Ophthalmology, Genetics and Maternal and Infantile Sciences (DINOGMI), University of Genova, Genova, IRCCS Policlinico San Martino, Italy 2., Genova, Italy), Sedano Tous, M. J., MD (Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Shahrizaila, N., MD (Neurology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Malaya), Sheikh, K., PhD (The University of Texas Health Science Center at Houston, Houston, USA), Silvestri, N. J., MD (Buffalo General Medical Center, Buffalo, Ny, Sommer, C. L., MD (Universitätsklinikum Würzburg, Würzburg, Germany), Varrato, J. D., DO (Lehigh Valley Health Network, Allentown, USA), Verschuuren, J., PhD (Leiden University Medical Centre, Leiden, Vytopil, M. V., Waheed, PhD (Tufts University School of Medicine Lahey Hospital W., MD (University of Vermont Medical Center, Burlington, USA), Zhou, L., PhD (Icahn School of Medicine at Mount Sinai, Badrising, USA). Other collaborators were:U. A., Bella, I. R., MD (University of Mass Medical School, Worcester, USA), Bunschoten, C., PhD candidate (Erasmus University Medical Centre, Rotterdam, Bürmann, J., Universitätsklinikum des Saarlandes, Homburg, Germany), Busby, M., Bradford, UK), Chao, C. C., PhD (National Taiwan University Hospital, Taipei, Taiwan), Conti, M. E., MD (University Hospital Clinicas, Dalakas, M. C., Thomas Jefferson University, MD (1., Philadelphia, Usa, National and Kapodistrian University of Athens, 2., Athens, Greece), Van Damme, P., PhD (University Hospital Leuven, Doets, A., van Dijk, G. W., MD (Canisius Wilhelmina Hospital, Nijmegen, Dimachkie, M. M., MD (University of Kansas Medical Center, Kansas, City, Doppler, K., Echaniz-Laguna, A., MD (Hopital de Hautepierre, Strasbourgh, France), Eftimov, F., PhD (Amsterdam University Medical Centre, Amsterdam, Fazio, R., MD (Scientific Institute San Raffaele, Fokke, C., MD (Gelre Hospital, Zutphen and Apeldoorn, Fulgenzi, E. A., MD (Hospital Cesar Milstein Buenos Aires, Garssen, M. P. J., PhD (Jeroen Bosch Hospital, Hertogenbosch, ’S, Zaltbommel and Drunen, Gijsbers, C. J., MD (Vlietland Hospital, Schiedam, Gilhuis, J., PhD (Reinier de Graaf Gasthuis, Delft, Grapperon, A., MD (CHU Timone, Hsieh, S. T., Illa, I., Islam, B., PhD (International Centre for Diarrhoeal Disease Research, Bangladesh, (icddr, Dhaka, b), Bangladesh), Jellema, K., PhD (Haaglanden Medisch Centrum, The, Hague, Kaida, K., PhD (National Defense Medical College, Saitama, Japan), Kokubun, N., MD (Dokkyo Medical University, Tochigi, Japan), Kolb, N., MD (University of Vermont, Burlington, Vt, van Koningsveld, R., PhD (Elkerliek Hospital, Helmond and Deurne, van der Kooi, A. J., Kuitwaard, K., PhD (Albert Schweitzer Hospital, Dordrecht, Landschoff Lassen, L., MD (Glostrup Hospital, Glostrup, Denmark), Leonhard, S. E., Mandarakas, M., PhD (Erasmus University Medical Centre, Martinez Hernandez, E., MD (Institut d’Investigacions Biomèdiques August Pi, i Sunyer (IDIBAPS), Hospital, Clinic, Mohammad, Q. D., PhD (National Institute of Neurosciences and Hospital, Dhaka, Bangladesh), Pulley, M., MD (University of Florida, Jacksonville, USA), Rajabally, Y. A., PhD (Queen Elizabeth Hospital, Birmingham, UK), Reddel, S. W., PhD (Concord Repatriation General Hospital, Sydney, Australia), van der Ree, T., (Westfriesgasthuis, Md, Hoorn, Roodbol, J., Sachs, G. M., MD (University of Rhode Island, Providence, USA), Samijn, J. P. A., PhD (Maasstad Hospital, Santoro, L., PhD (University Federico II, Napels, Italy), Stein, B., Joseph’s Regional Medical Center, MD (St., Paterson, USA), Vermeij, F. H., MD (Franciscus Gasthuis, Visser, L. H., PhD (Elisabeth-TweeSteden Hospital, Tilburg and Waalwijk, Willison, H. J., PhD (University of Glasgow, Wirtz, P., Phd, (HagaZiekenhuis, Zivkovich, S. A., PhD (University of Pittsburgh Medical Center, and Pittsburgh, USA).
- Subjects
treatment ,disability evaluation ,drug administration schedule ,adult ,guillain-barré syndrome ,poor prognosis ,second ivig course ,aged ,female ,guillain-barre syndrome ,humans ,immunoglobulin g ,immunoglobulins ,intravenous ,immunologic factors ,male ,middle aged ,prognosis ,time factors ,treatment outcome - Published
- 2020
35. Preliminary results of CoQtz-N: a quartz reference material for terrestrial in-situ cosmogenic ¹⁰Be and ²⁶Al measurements
- Author
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Binnie, S.A., Dewald, A., Heinze, S., Voronina, E., Hein, A., Wittmann, H., von Blanckenburg, F., Hetzel, R., Christl, M., Schaller, M., Léanni, L., ASTER Team, Hippe, K., Vockenhuber, C., Ivy-Ochs, S., Maden, C., Fülöp, R-H., Fink, D., Wilcken, K.M., Fujioka, T., Fabel, D., Freeman, S.P.H.T., Xu, S., Fifield, L.K., Akçar, N., Spiegel, C., and Dunai, T.J.
- Abstract
There is growing interest in geochronological applications of terrestrial in situ-produced cosmogenic nuclides, with the most commonly measured being ¹⁰Be and ²⁶Al in quartz. To extract and then separate these radionuclides from quartz and prepare them in the oxide form suitable for accelerator mass spectrometry (AMS) requires extensive and careful laboratory processing. Here we discuss the suitability of a crushed, sieved and etched, sub-aerially exposed vein quartz specimen (CoQtz-N) to act as a reference material for chemical laboratory preparation and AMS measurements. Splits of CoQtz-N were distributed to eleven target preparation laboratories. The CoQtz-N ¹⁰Be targets were then measured at seven different AMS facilities and five of the preparation laboratories had their ²⁶Al targets measured at four different AMS facilities. We show that CoQtz-N splits are sufficiently homogeneous with regard to nuclide concentrations, that it has been cleaned of any atmospheric derived (i.e. meteoric) ¹⁰Be and that it has low concentrations of the major elements that can interfere with Be and Al extraction chemistry and AMS measurements. We derive preliminary concentrations for ¹⁰Be and ²⁶Al in CoQtz-N as 2.53 ± 0.09 × 106 at/g and 15.6 ± 1.6 × 106 at/g, respectively, at the 95% confidence limit.
- Published
- 2019
36. Single nucleotide polymorphisms in the gene encoding Krüppel-like factor 7 are associated with type 2 diabetes
- Author
-
Kanazawa, A., Kawamura, Y., Sekine, A., Iida, A., Tsunoda, T., Kashiwagi, A., Tanaka, Y., Babazono, T., Matsuda, M., Kawai, K., Iiizumi, T., Fujioka, T., Imanishi, M., Kaku, K., Iwamoto, Y., Kawamori, R., Kikkawa, R., Nakamura, Y., and Maeda, S.
- Published
- 2005
- Full Text
- View/download PDF
37. Trace gas monitor based on difference frequency generation at 4 μm using mass-production laser diodes as pump and signal light sources
- Author
-
Takahashi, M., Ohara, S., Tezuka, T., Ashizawa, H., Endo, M., Yamaguchi, S., Nanri, K., and Fujioka, T.
- Published
- 2004
- Full Text
- View/download PDF
38. Successful treatment of bcr/abl-positive acute mixed lineage leukemia by unmanipulated bone marrow transplantation from an HLA-haploidentical (3-antigen-mismatched) cousin
- Author
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Ikegame, K, Mukouchi, C, Kunitomi, A, Konaka, Y, Kawakami, M, Nishida, S, Taniguchi, Y, Fujioka, T, Masuda, T, Murakami, M, Hosen, N, Kim, E H, Tsuboi, A, Oji, Y, Oka, Y, Sugiyama, H, Kawase, I, and Ogawa, H
- Published
- 2003
- Full Text
- View/download PDF
39. Successful treatment of refractory T-cell acute lymphoblastic leukemia by unmanipulated stem cell transplantation from an HLA 3-loci mismatched (haploidentical) sibling
- Author
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Ikegame, K, Tanji, Y, Kitai, N, Tamaki, H, Kawakami, M, Fujioka, T, Oka, Y, Maruya, E, Saji, H, Sugiyama, H, and Ogawa, H
- Published
- 2003
- Full Text
- View/download PDF
40. DIFFERENT IL-8 EXPRESSION IN HELICOBACTER PYLORI INFECTED GASTRIC MUCOSA BETWEEN BHUTAN AND THE DOMINICAN REPUBLIC: Abstract no.: P05.05
- Author
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Nagashima, H., Iwatani, S., Cruz, M., Jimenez Abreu, J. A., Mahachai, V., Vilaichone, R., Uchida, T., Shiota, S., Tshering, L., Fujioka, T., Graham, D. Y., and Yamaoka, Y.
- Published
- 2013
41. Frequency of CD4+ FOXP3+ regulatory T-cells at early stages after HLA-mismatched allogeneic hematopoietic SCT predicts the incidence of acute GVHD
- Author
-
Fujioka, T, Tamaki, H, Ikegame, K, Yoshihara, S, Taniguchi, K, Kaida, K, Kato, R, Inoue, T, Nakata, J, Ishii, S, Soma, T, Okada, M, and Ogawa, H
- Published
- 2013
- Full Text
- View/download PDF
42. Single-nucleotide polymorphisms in the class II region of the major histocompatibility complex in Japanese patients with immunoglobulin A nephropathy
- Author
-
Akiyama, F., Tanaka, T., Yamada, R., Ohnishi, Y., Tsunoda, T., Maeda, S., Takei, T., Obara, W., Ito, K., Honda, K., Uchida, K., Tsuchiya, K., Nitta, K., Yumura, W., Nihei, H., Ujiie, T., Nagane, Y., Miyano, S., Suzuki, Y., Fujioka, T., Narita, I., Gejyo, F., and Nakamura, Y.
- Published
- 2002
- Full Text
- View/download PDF
43. Activation of phosphatidylinositol 3-kinase via epidermal growth factor receptor in isolated rat hepatocytes
- Author
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Fujioka, T., Ui, M., and Shimonishi, Yasutsugu, editor
- Published
- 2002
- Full Text
- View/download PDF
44. The Study of Water Structure in Aqueous Solutions of Butoxyethanol by Enthalpy of Mixing Measurements
- Author
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Nakayama, H., Kanenaga, H., and Fujioka, T.
- Published
- 2001
- Full Text
- View/download PDF
45. The OPERA film: New nuclear emulsion for large-scale, high-precision experiments
- Author
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Nakamura, Taku, Ariga, A., Ban, T., Fukuda, Takako, Fukuda, Tutomu, Fujioka, T., Furukawa, T., Hamada, K., Hayashi, H., Hiramatsu, S., Hoshino, K., Kawada, J., Koike, N., Komatsu, M., Matsuoka, H., Miyamoto, S., Miyanishi, K., Miyanishi, M., Morishima, K., Nada, H., Naganawa, N., Nakano, T., Narita, K., Natsume, M., Niwa, K., Nonaka, N., Park, B.D., Sato, O., Takahashi, S., Toshito, T., Uetake, T., Nakamura, M., Kuwabara, K., Nishiyama, S., Nonoyama, Y., and Kodama, K.
- Published
- 2006
- Full Text
- View/download PDF
46. High-pressure subsonic mode operation of chemical oxygen-iodine laser
- Author
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Wani, F., Endo, M., and Fujioka, T.
- Published
- 2000
- Full Text
- View/download PDF
47. Introduction to The Neurosciences and Music IV: Learning and Memory
- Author
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Altenmüller, E., Demorest, S. M., Fujioka, T., Halpern, A. R., Hannon, E. E., Loui, P., Majno, M., Oechslin, M. S., Osborne, N., Overy, K., Palmer, C., Peretz, I., Pfordresher, P. Q., Särkämö, T., Wan, C. Y., and Zatorre, R. J.
- Published
- 2012
- Full Text
- View/download PDF
48. HISTOLOGICAL CHARACTERISTIC OF H. PYLORI INFECTED GASTRITIS IN NEPAL: Abstract no.: P08.12
- Author
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Kobayakawa, M., Akiyama, J., Shrestha, P. K., Uchida, T., Fujioka, T., and Uemura, N.
- Published
- 2011
49. HIGH PREVALENCE OF METRONIDAZOLE RESISTANT H. pylori IN BHUTAN: Abstract no.: P07.02
- Author
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Vilaichone, R., Tshering, L., Ratanachu-Ek, T., Uchida, T., Yamaoka, Y., Fujioka, T., and Mahachai, V.
- Published
- 2011
50. EVALUATION OF DIAGNOSTIC TESTS FOR H. pylori INFECTION IN THE BHUTANESE POPULATION: Abstract no.: P06.12
- Author
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Uchida, T., Vilaichone, R., Ratanachu-ek, T., Mahachai, V., Tshering, L., Fujioka, T., and Yamaoka, Y.
- Published
- 2011
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