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4 results on '"G, Azaceta Reinares"'

1. [Persistence of hypercoagulability state after hip and knee arthroplasty: what is the optimal duration of antithrombotic guidelines in this surgery?]

Author

T, Iturbe Hernández, R, Cornudella Lacasa, R, de Miguel Olmeda, G, Azaceta Reinares, M A, Fuertes Palacio, F, Seral Iñigo, and M, Gutiérrez Martín

Subjects
Male, Time Factors, Arthroplasty, Replacement, Hip, Antithrombin III, Enzyme-Linked Immunosorbent Assay, Middle Aged, Blood Coagulation Factors, Fibrinolytic Agents, Humans, Thrombophilia, Female, Arthroplasty, Replacement, Knee, Biomarkers, Aged, Peptide Hydrolases
Abstract

Among 79 patients candidates to hip (53) and knee (26) replacement an evaluation was made of the influence of a two-week program with LMWH on the evolution of hypercoagulability markers: D-D, TAT, and F1 + 2. Measurements were performed by ELISA preoperatively and on days 1, 7 and about 45 postoperatively; in the latter, two extraction intervals were considered:or = 45 days and45 days. With both surgical modalities, D-D and F1 + 2 peaked at 7th day postoperatively, whereas TAT peaked on day 1. Among D-D and F1 + 2 values quantitated on day 7th and the extraction intervalor = 45 days, no significant differences were obtained (Z2.64). The hypercoagulative chronicity exhibited by D-D and F1 + 2 during the first month and a half after this surgery, might require in some cases a more prolonged thromboprophylaxis.

Published
1999

2. [Discordant lymphoma: a report of 2 new cases and a review of the literature]

Author

G, Azaceta Reinares, J M, Domingo Morera, P, Rabasa Baraibar, and L, Palomera Bernal

Subjects
Neoplasms, Multiple Primary, Fatal Outcome, Recurrence, Lymphoma, Non-Hodgkin, Terminology as Topic, Humans, Female, Combined Modality Therapy, Hodgkin Disease, Leukemia, Lymphocytic, Chronic, B-Cell, Aged
Abstract

The simultaneous occurrence of two different histologic types of lymphoma in one location ("composite" lymphoma) or in different anatomical locations ("discordant" lymphoma) is uncommon, particularly the association of Hodgkin's disease (HD) and non-Hodgkin's disease (NHD). Therefore, both conditions have long been considered well differentiated entities, and its association qualified as a chance event. Two cases of "discordant" lymphoma are reported. In both cases the histologic type was HD with mixed cellularity, associated with immunoblastic B lymphoma in case 1 and CLL-B in case 2. Some recent series seem to indicate that this phenomenon occurs more commonly than what could be reasonably attributed to chance alone, suggesting the analysis of cases associating HD and NHD with CLL-B a possible clonal relationship between these conditions. The Reed-Sternberg cell might thus originate from an altered B-lymphocyte.

Published
1999

3. [Persistence of hypercoagulability state after hip and knee arthroplasty: what is the optimal duration of antithrombotic guidelines in this surgery?].

Author

Iturbe Hernández T, Cornudella Lacasa R, de Miguel Olmeda R, Azaceta Reinares G, Fuertes Palacio MA, Seral Iñigo F, and Gutiérrez Martín M

Subjects
Aged, Antithrombin III analysis, Biomarkers, Blood Coagulation Factors analysis, Enzyme-Linked Immunosorbent Assay, Female, Humans, Male, Middle Aged, Peptide Hydrolases analysis, Thrombophilia drug therapy, Thrombophilia etiology, Time Factors, Arthroplasty, Replacement, Hip adverse effects, Arthroplasty, Replacement, Knee adverse effects, Fibrinolytic Agents administration & dosage, Thrombophilia diagnosis
Abstract

Among 79 patients candidates to hip (53) and knee (26) replacement an evaluation was made of the influence of a two-week program with LMWH on the evolution of hypercoagulability markers: D-D, TAT, and F1 + 2. Measurements were performed by ELISA preoperatively and on days 1, 7 and about 45 postoperatively; in the latter, two extraction intervals were considered: < or = 45 days and > 45 days. With both surgical modalities, D-D and F1 + 2 peaked at 7th day postoperatively, whereas TAT peaked on day 1. Among D-D and F1 + 2 values quantitated on day 7th and the extraction interval < or = 45 days, no significant differences were obtained (Z < 2.64). The hypercoagulative chronicity exhibited by D-D and F1 + 2 during the first month and a half after this surgery, might require in some cases a more prolonged thromboprophylaxis.

Published
1999

4. [Discordant lymphoma: a report of 2 new cases and a review of the literature].

Author

Azaceta Reinares G, Domingo Morera JM, Rabasa Baraibar P, and Palomera Bernal L

Subjects
Aged, Combined Modality Therapy, Fatal Outcome, Female, Hodgkin Disease therapy, Humans, Leukemia, Lymphocytic, Chronic, B-Cell therapy, Lymphoma, Non-Hodgkin therapy, Neoplasms, Multiple Primary therapy, Recurrence, Terminology as Topic, Hodgkin Disease pathology, Leukemia, Lymphocytic, Chronic, B-Cell pathology, Lymphoma, Non-Hodgkin pathology, Neoplasms, Multiple Primary pathology
Abstract

The simultaneous occurrence of two different histologic types of lymphoma in one location ("composite" lymphoma) or in different anatomical locations ("discordant" lymphoma) is uncommon, particularly the association of Hodgkin's disease (HD) and non-Hodgkin's disease (NHD). Therefore, both conditions have long been considered well differentiated entities, and its association qualified as a chance event. Two cases of "discordant" lymphoma are reported. In both cases the histologic type was HD with mixed cellularity, associated with immunoblastic B lymphoma in case 1 and CLL-B in case 2. Some recent series seem to indicate that this phenomenon occurs more commonly than what could be reasonably attributed to chance alone, suggesting the analysis of cases associating HD and NHD with CLL-B a possible clonal relationship between these conditions. The Reed-Sternberg cell might thus originate from an altered B-lymphocyte.

Published
1998

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