134 results on '"Gürlek, Alper"'
Search Results
2. Oxysterol species generated by auto-oxidation in subclinical hypothyroidism
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Ünlütürk, Uğur, Savaş, Merve, Oğuz, Seda Hanife, Samadi, Afshin, Fırlatan, Büşra, Yüce, Deniz, Lay, İncilay, and Gürlek, Alper
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- 2021
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3. Lymph Node ACTH Washout: New Assistant Method for Localizing the Source of Ectopic ACTH Secretion in a Case of Metastatic Medullary Thyroid Carcinoma.
- Author
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İşler, Alperen Onur, Şendur, Süleyman Nahit, İremli, Burçin Gönül, Cennet, Ömer, Doğrul, Ahmet Bülent, Uysal, Serkan, Portakal, Oytun, Kiki, Zehranur, Oruç, Aleyna, Ünlütürk, Uğur, and Gürlek, Alper
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CUSHING'S syndrome diagnosis ,LYMPH nodes ,MULTIPLE endocrine neoplasia ,HYPERADRENOCORTICISM ,CYTOLOGY ,THYROID gland tumors ,LYMPHADENECTOMY ,COMPUTED tomography ,PROTEIN-tyrosine kinase inhibitors ,ANTINEOPLASTIC agents ,MAGNETIC resonance imaging ,POSITRON emission tomography ,CALCITONIN ,METASTASIS ,CLINICAL pathology ,ADRENOCORTICOTROPIC hormone ,CANCER cells ,NEEDLE biopsy ,PYRIDINE ,THYROIDECTOMY ,NECK surgery - Abstract
In ACTH-dependent Cushing syndrome, identifying the source of ACTH can be challenging. A 23-year-old male presented with Cushingoid symptoms and signs to other clinics. Laboratory tests confirmed ACTH-dependent Cushing's syndrome. Imaging revealed a suspicious adenoma in the pituitary, a hypoechoic nodule in the thyroid, and pathological-appearing lymph nodes in the neck. Following a fine needle aspiration cytological examination, medullary thyroid carcinoma was diagnosed. A total thyroidectomy and lymph node dissection were subsequently performed. The pathology report confirmed medullary thyroid carcinoma. When the patient was admitted to our hospital, disease recurrence was considered, and lymph node ACTH washout was performed as an unusual method to identify the source of ACTH. The washout sample yielded a very high value of 958 pg/mL. We describe a patient who was hospitalized with severe symptoms of Cushing's syndrome resulting from medullary thyroid cancer. We employed a novel method involving lymph node ACTH washout to identify the source of ACTH production. Lymph node ACTH washout can be an effective diagnostic option to determine the origin of ACTH. [ABSTRACT FROM AUTHOR]
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- 2024
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- View/download PDF
4. The determination of heart failure with preserved systolic function by using Galectin-3 and other cardiac markers is affected by vitamin D status
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Erdevir, Mehmet, primary, Evranos, Banu, additional, Oğuz, Seda Hanife, additional, Zekeriyev, Samuray, additional, İremli, Burçin Gönül, additional, Karakaya, Jale, additional, Lay, İncilay, additional, and Gürlek, Alper, additional
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- 2023
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5. The role of PEDF, VEGF, and Ki-67 in tissue invasion and tumor angiogenesis of medullary thyroid carcinoma
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Kazimzade, Gulnar, primary, Kurtulan, Olcay, additional, Akyol, Aytekin, additional, Bakır, Sinem, additional, Karakaya, Jale, additional, Sökmensüer, Cenk, additional, and Gürlek, Alper, additional
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- 2023
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6. Emergence of Autoimmune Type 1 Diabetes and Acute Adrenal Crisis Following Coronavirus Disease 2019.
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Oğuz, Seda Hanife and Gürlek, Alper
- Subjects
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DIAGNOSIS of endocrine diseases , *AUTOIMMUNE disease diagnosis , *PHYSICAL diagnosis , *COVID-19 , *ENDOCRINE diseases , *AUTOIMMUNE diseases , *TYPE 1 diabetes , *RISK assessment , *INSULIN , *TREATMENT effectiveness , *DESCRIPTIVE statistics , *ROUTINE diagnostic tests , *COMPUTED tomography , *DISEASE risk factors - Abstract
A 60-year-old male presented with extreme fatigue and weight loss 3 weeks after testing positive for coronavirus disease 2019. The course of coronavirus disease 2019 was mild, without pulmonary involvement. The patient showed symptoms and laboratory signs of new-onset diabetes without ketoacidosis and acute primary adrenal insufficiency, the latter of which was confirmed with an adrenocorticotrophic hormone stimulation test. Glutamic acid decarboxylase-65 antibody and antibodies to the adrenal cortex were positive in high titers. Previous medical records of the patient revealed no hyperglycemia or electrolyte abnormalities prior to current admission, but an earlier test result was compatible with primary hypothyroidism which was associated with autoimmune thyroiditis. He was therefore diagnosed with autoimmune polyglandular syndrome type II. Clinical and laboratory findings improved after starting appropriate hormone replacement therapies along with insulin. Coronavirus disease 2019 may induce a variety of autoimmune disorders in susceptible subjects. In our case, coronavirus disease 2019 might have simply precipitated type 1 diabetes and adrenal insufficiency in whom autoimmune thyroiditis may have been the first manifestation of an undiagnosed autoimmune polyglandular syndrome type II. Coronavirus disease 2019 might have triggered autoimmunity in the patient who was possibly predisposed to autoimmune disorders. Anyhow, more research is required to evaluate the possible link between coronavirus disease 2019 and autoimmune disorders. [ABSTRACT FROM AUTHOR]
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- 2024
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7. Molecular Pathological Markers and TERT Promoter Mutations: Correlations with Clinicopathological Features and Distant Metastasis in Turkish Patients with Papillary Thyroid Carcinoma.
- Author
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Yılmaz, Ezgi, Güler, Gaye, Kurtulan, Olcay, Karakaya, Jale, Telli, Tuğçe, Tuncel, Murat, and Gürlek, Alper
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BIOMARKERS ,PROMOTERS (Genetics) ,REVERSE transcriptase polymerase chain reaction ,GENETIC mutation ,TELOMERASE ,THYROID gland tumors ,CANCER invasiveness ,METASTASIS ,CANCER relapse ,CANCER patients ,PEARSON correlation (Statistics) ,CHI-squared test ,DATA analysis software ,SYMPTOMS - Abstract
Objective: Studies concerning the frequency of BRAFV600E, TERT promoter, and NRAS mutations, RET/PTC and PAX8/PPARγ rearrangements, and their correlations with distant metastasis and several clinicopathological parameters are lacking in Turkish papillary thyroid carcinoma (PTC) patients. Methods: Mutations were detected by real-time polymerase chain reaction (PCR) from paraffinembedded tumor tissues obtained from 42 PTC patients (16 with and 26 without distant metastasis, median age 52 years, range 21-80). Results: The follow-up period was a median of 41.38 (range 1-168) months. A relationship was found between distant metastasis and aggressive histological variant (P = .008), capsular (P = .001), lymphovascular (P = .001) and extrathyroidal invasion (P = .002), advanced stage (P = .002), and recurrence (P = .008). Mortality was greater in the distant-metastatic group (P = .002). The frequency of BRAFV600E mutation was 67.5% (27/40). Of the BRAFV600E mutation-positive group, 22.2% (6/27) had distant metastasis and 77.8% (21/27) had no metastasis (P = .006). No significant difference existed between BRAFV600E mutation-positive and -negative groups concerning the clinicopathological features. The mortality rate was higher in the BRAF mutation-negative group compared with the positive group (P = .03). The frequency of TERT mutation (all at position C228T) was 9.5% (4/42), showing no correlation with any clinicopathological feature. NRAS mutation and PAX8/PPARγ rearrangement were not observed. RET/PTC gene rearrangement was detected in only 2 patients. Conclusion: Our findings suggest that molecular changes, contrary to previous observations in different populations, are not related with aggressive behavior and distant metastasis in Turkish PTC patients. Low number of patients and short follow-up, however, might have hindered the ability to draw accurate conclusions regarding molecular markers and poor prognosis in such a slow-growing carcinoma type. [ABSTRACT FROM AUTHOR]
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- 2023
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8. Association of Human Leukocyte Antigen Genotypes with Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine-Induced Subacute Thyroiditis
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Şendur, Süleyman Nahit, primary, Özmen, Füsun, additional, Oğuz, Seda Hanife, additional, İremli, Burçin Gönül, additional, Malkan, Ümit Yavuz, additional, Gürlek, Alper, additional, Erbas, Tomris, additional, and Ünlütürk, Uğur, additional
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- 2022
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9. SARS-CoV-2 Vaccine–induced Thyroiditis: Safety of Revaccinations and Clinical Follow-up
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Oğuz, Seda Hanife, primary, Şendur, Süleyman Nahit, additional, İremli, Burçin Gönül, additional, Gürlek, Alper, additional, Erbas, Tomris, additional, and Ünlütürk, Uğur, additional
- Published
- 2022
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10. Landscape of Familial Isolated and Young-Onset Pituitary Adenomas: Prospective Diagnosis in AIP Mutation Carriers
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Hernández-Ramírez, Laura C., Gabrovska, Plamena, Dénes, Judit, Stals, Karen, Trivellin, Giampaolo, Tilley, Daniel, Ferraù, Francesco, Evanson, Jane, Ellard, Sian, Grossman, Ashley B., Roncaroli, Federico, Gadelha, Mônica R., Korbonits, Márta, Agha, Amar, Akker, Scott A., Aflorei, Elena D., Alföldi, Sándor, Arlt, Wiebke, Atkinson, Brew, Aulinas-Masó, Anna, Aylwin, Simon J., Backeljauw, Philippe F., Badiu, Corin, Baldeweg, Stephanie, Bano, Gul, Barkan, Ariel, Barwell, Julian, Bernal-González, Carmen, Besser, G. Michael, Bevan, John S., Blair, Jo, Bouloux, Pierre, Bradley, Lisa, Buchfelder, Michael, Cakir, Mehtap, Canham, Natalie, Carroll, Paul, Chahal, Harvinder S., Cheetham, Tim, Chentli, Farida, Clayton, Richard N., Cohen, Mark, Cole, Trevor, Courtney, Hamish, Crowne, Elizabeth, Cuthbertson, Daniel, Dal, Jacob, Dalantaeva, Nadezhda, Daousi, Christina, Darzy, Ken, Dattani, Mehul, Davies, Justin H., Davis, Julian, De Castro, Margaret, De Marinis, Laura, Drake, William, Dutta, Pinaki, Dzeranova, Larisa, Edén-Engström, Britt, Eeles, Rosalind, Elfving, Maria, Elston, Marianne, Emmerson, Louise, Fersht, Naomi, Fica, Simona, Fischli, Stefan, Flanagan, Daniel, Fleseriu, Maria, Freda, Pamela U., Friedman, Theodore, Frohman, Lawrence A., Gallego, Patricia, Gevers, Evelien, Gláz, Edit, Goldman, James A., Goldstone, Anthony P., Goth, Miklos, Greenhalgh, Lynn, Grieve, Joan, Guitelman, Mirtha, Gürlek, Alper, Gurnell, Mark, Horvath, Katalin, Howlett, Trevor A., Höybye, Charlotte, Hunter, Steven, Iacovazzo, Donato, Igaz, Peter, Inder, Warrick J., Iwata, Takeo, Izatt, Louise, Jagadeesh, Sujatha, Kaltsas, Gregory, Kaplan, Felicity, Karavitaki, Niki, Kastelan, Darko, Katz, Michelle, Kearney, Tara, Khoo, Bernard, Kiraly-Borri, Cathy, Knispelis, Robertas, Kovács, Gábor László, Kumar, Ajith V., Laws, Edward R., Jr, Lechan, Ronald M., Levy, Miles J., Lewandowski, Krzysztof, Lo, Janet, Maartens, Niki, Matsuno, Akira, McGowan, Barbara, McQuaid, Siobhán E., Medic-Stojanoska, Milica, Mercado-Atri, Moisés, Mezősi, Emese, Miljic, Dragana, Miller, Karen K., Modenesi, Silvia, Molitch, Mark E., Monson, John, Morris, Damian G., Morrison, Patrick J., Munir, Alia, Murray, Robert D., Musat, Madalina, Musolino, Nina, Nachtigall, Lisa, Newell-Price, John, Ogilvie, Arla, Orme, Steve M., Paşcanu, Ionela, Patócs, Attila, Patterson, Catherine, Pearce, Simon H., Pecori Giraldi, Francesca, Pfeifer, Marija, Popovic, Vera, Poplawski, Nicola, Powell, Michael, Pullan, Peter, Quinton, Richard, Radian, Serban, Randeva, Harpal, Ribeiro-Oliveira, Antônio, Jr, Rodd, Celia, Ryan, Fiona, Salvatori, Roberto, Schöfl, Christof, Shears, Debbie, Shotliff, Kevin, Soares, Beatriz S., Somasundaram, Noel, Spada, Anna, Sperber, James, Spoudeas, Helen A., Stewart, Susan, Storr, Helen, Strasburger, Christian, Street, Maria Elisabeth, Swords, Francesca, Thakker, Rajesh V., Tham, Elaine, Thompson, Chris, Thorner, Dr Michael O., Tóth, Miklós, Trainer, Peter J., Tsagarakis, Stylianos, Tzanela, Marinella, Vadász, János, Vaks, Vladimir, Verkauskiene, Rasa, Wass, John A., Webb, Susan M., Weber, Astrid, Yamada, Shozo, Yarman, Sema, Yeoh, Philip, Yoshimoto, Katsuhiko, and Zammitt, Nicola N.
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- 2015
11. Early promising results for the endoscopic surgical treatment of Cushing’s disease
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Berker, Mustafa, Işikay, Ilkay, Berker, Dilek, Bayraktar, Miyase, and Gürlek, Alper
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- 2014
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12. Emergence of Autoimmune Type 1 Diabetes and Acute Adrenal Crisis Following COVID-19
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Oğuz, Seda Hanife, primary and Gürlek, Alper, additional
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- 2021
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13. Complications of endoscopic surgery of the pituitary adenomas: analysis of 570 patients and review of the literature
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Berker, Mustafa, Hazer, Derya Burcu, Yücel, Taşkın, Gürlek, Alper, Cila, Ayşenur, Aldur, Mustafa, and Önerci, Metin
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- 2012
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14. Change in amputation predictors in diabetic foot disease: effect of multidisciplinary approach
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Aydin, Kadriye, Isildak, Mehlika, Karakaya, Jale, and Gürlek, Alper
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- 2010
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15. Role of adipocytokines in predicting the development of diabetes and its late complications
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Gulcelik, Nese Ersoz, Usman, Aydan, and Gürlek, Alper
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- 2009
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16. Circulating adiponectin represents a biomarker of the association between adiposity and bone mineral density
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Ağbaht, Kemal, Gürlek, Alper, Karakaya, Jale, and Bayraktar, Miyase
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- 2009
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17. Evaluation of subclinical coronary atherosclerosis in mild asymptomatic primary hyperparathyroidism patients
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Kepez, Alper, Harmanci, Ayla, Hazirolan, Tuncay, Isıldak, Mehlika, Kocabas, Ugur, Ates, Ahmet, Ciftci, Orcun, Tokgozoglu, Lale, and Gürlek, Alper
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- 2009
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18. Simultaneous determination of rosiglitazone and metformin in plasma by gradient liquid chromatography with UV detection
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Yardımcı, Ceren, Özaltın, Nuran, and Gürlek, Alper
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- 2007
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19. Endogenous sex steroid, GH and IGF-I levels in normal elderly men: Relationships with bone mineral density and markers of bone turnover
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Gürlek, Alper and Gedik, O.
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- 2001
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20. Pigment epithelium-derived factor increases in type 2 diabetes after treatment with metformin
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Akn, Şafak, Aksoy, Duygu Yazgan, Çnar, Neşe, Aydn, Kadriye, Karaağaoğlu, Ergun, Aryürek, Macit, Gülçelik, Neşe Ersöz, Usman, Aydan, and Gürlek, Alper
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- 2012
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21. İNSİDENTAL ADRENAL LEZYONLARIN KLİNİK, HORMONAL VE HİSTOLOJİK DEĞERLENDİRİLMESİ: TEK MERKEZ SONUÇLARI
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AKIN, Şafak, primary, DAĞDELEN, Selçuk, additional, YILDIZ, Bülent Okan, additional, GÜRLEK, Alper, additional, ERBAŞ, Tomris, additional, and BAYRAKTAR, Miyase, additional
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- 2020
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22. Apoptosis Inhibitor of Macrophage, Monocyte Chemotactic Protein-1, and C-Reactive Protein Levels Are Increased in Patients with Metabolic Syndrome: A Pilot Study
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Savaş, Emine Merve, primary, Oğuz, Seda Hanife, additional, Samadi, Afshin, additional, Yılmaz Işıkhan, Selen, additional, Ünlütürk, Uğur, additional, Lay, İncilay, additional, and Gürlek, Alper, additional
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- 2020
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23. Clinical and demographic aspects of Paget disease of bone: a multicentric study from Turkey
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Deyneli, Oğuzhan (ORCID 0000-0001-6582-7031 & YÖK ID 171914), Yavuz, Dilek Gogas; Aytürk, Semra; Çetinkalp, Şevki; Bayraktar, Fırat; Kulaksızoğlu, Mustafa; Hekimsoy, Zeliha; Aydın, Hasan; Uygur, Melin; Deniz, Ferhat; İpekçi, Süleyman; Atmaca, Ayşegül; Saraç, Fulden; Özdemir, Nilüfer; Cantürk, Zeynep; Mert, Meral; Sancak, Seda; Ertörer, Eda; Duran, Cevdet; Akarsu, Ersin; Selek, Alev; Gürlek, Alper, School of Medicine, Deyneli, Oğuzhan (ORCID 0000-0001-6582-7031 & YÖK ID 171914), Yavuz, Dilek Gogas; Aytürk, Semra; Çetinkalp, Şevki; Bayraktar, Fırat; Kulaksızoğlu, Mustafa; Hekimsoy, Zeliha; Aydın, Hasan; Uygur, Melin; Deniz, Ferhat; İpekçi, Süleyman; Atmaca, Ayşegül; Saraç, Fulden; Özdemir, Nilüfer; Cantürk, Zeynep; Mert, Meral; Sancak, Seda; Ertörer, Eda; Duran, Cevdet; Akarsu, Ersin; Selek, Alev; Gürlek, Alper, and School of Medicine
- Abstract
Objective: Paget disease of bone (PDB) is a metabolic bone disease that has been rarely reported in the Eastern countries. This study aimed to evaluate the clinical and demographic characteristics of patients with PDB followed up at endocrinology clinics in Turkey. Methods: an invitation was sent to tertiary endocrinology clinics to complete a survey on the demographic, clinical, radiological, and laboratory parameters, as well as treatment modalities of patients with PDB. This study enrolled clinically and radiologically proven 185 patients with PDB from 18 endocrinology centers based in 10 cities of Turkey. Results: this cohort of PDB had female preponderance (women/men: 105/80) with a mean age, during diagnosis, of 57±10 years. Most of the patients (59.6%) were symptomatic at diagnosis. Bone pain and headache were the predominant clinical symptoms. Polyostotic disease was observed in 67.5% (n=125) of patients. Frequently affected bones were skull (41.6%), pelvis (53.5%), spine (41%), and femur (25.4%). Moreover, 17 patients with skull involvement had hearing loss. Mean serum alkaline phosphatase (ALP) level (552±652 IU/L; range: 280-5762 IU/L) was over the normal reference cutoff with normal serum calcium levels. Intravenous bisphosphonates (zoledronic acid, 5 mg; pamidronate, 60-90 mg) were the most used drugs (75%) for the treatment of PDB. Most of the patients (87.1%) treated with intravenous bisphosphonates responded well, with a decrease in serum ALP level (117±114 IU/L) in the 12th month of therapy. Furthermore, 16 patients relapsed after the second year of therapy; 3 patients did not respond to the initial intravenous bisphosphonate treatment. Conclusion: the patients with PDB followed up by endocrinology clinics of Turkey exhibited polyostotic disease with classical clinical, radiological, and biochemical features and women's predominance with good response to intravenous bisphosphonate therapy., NA
- Published
- 2020
24. Coincidence or Causality: Celiac and Crohn Diseases in a Case of Turner Syndrome
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Durusu, Mine, Gürlek, Alper, Şimşek, Halis, Balaban, Yasemin, and Tatar, Gonca
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- 2005
25. Increased Plasma PAI-1 in Relatives of Type 2 Diabetic Patients
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Gürlek, Alper, Bayraktar, Miyase, and Kirazli, Serafettin
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- 2000
26. Increased Plasminogen Activator Inhibitor-1 Activity in Offspring of Type 2 Diabetic Patients: Lack of association with plasma insulin levels
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Gürlek, Alper, Bayraktar, Miyase, and Kirazli, Serafettin
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- 2000
27. Thyroid volumes and serum VEGF levels in dyslipidemic patients: effects of statin treatment
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AYDIN, Kadriye, primary, ERSÖZ GÜLÇELİK, Neşe, additional, TUNCEL, Murat, additional, BALCI, Cafer, additional, AKIN, Şafak, additional, ÇINAR, Neşe, additional, FIRAT, Firuzan, additional, ÇAĞLAR, Meltem, additional, USMAN, Aydan, additional, and GÜRLEK, Alper, additional
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- 2019
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28. O-10 Lymph node ACTH washout determined the source of ACTH secretion in a patient with Cushing's Syndrome due to medullary thyroid cancer.
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Onur İşler, Alperen, Nahit Şendur, Süleyman, Gönül İremli, Burçin, Ünlütürk, Uğur, Cennet, Ömer, Bülent Doğrul, Ahmet, and Gürlek, Alper
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MEDULLARY thyroid carcinoma ,THYROID cancer ,CUSHING'S syndrome ,ADRENOCORTICOTROPIC hormone ,LYMPH nodes ,NEEDLE biopsy ,LYMPHADENECTOMY - Abstract
Introduction: Ectopic ACTH syndrome constitutes 18% of Cushing's syndrome cases, and in rare cases, ACTH secretion from medullary thyroid cancer cells is the source of ectopic ACTH production. Here we report a catastrophic Cushing's syndrome case owing to medullary thyroid cancer in which the source of ACTH production was demonstrated by lymph node ACTH washout. Clinical Case: A 23 year-old male was admitted to other clinics with complaints of inability to lose weight despite diet and exercise, and weight gain of approximately 40 kg, which had been going on for the last two years. At his application, his weight was 160 kg and his body mass index was 42.51 kg/m
2 . On physical examination, clinical stigmata suggesting Cushing's syndrome such as moon face, buffalo hump, supraclavicular fat deposition, acanthosis nigricans, centripedal obesity, purple striae on the abdomen were noted. The biochemical and hormonal evaluation confirmed ACTH-dependent Cushing's syndrome (Table 1). To establish the source of excess ACTH, first, a pituitary MRI was performed which revealed a 4×2 mm adenoma on the left side of the gland. In PET-CT, a 24×20 mm hypoechoic nodule in the inferior of the right thyroid lobe, and several pathological lymph nodes at the right side of the neck were detected. Serum calcitonin levels were high (6528 ng/L) and fine-needle aspiration biopsy from the thyroid nodule documented medullary thyroid cancer. The patient underwent bilateral total thyroidectomy and right cervical lymph node dissection. The pathology report was compatible with metastatic medullary thyroid cancer. After surgery, the remission of hypercortisolemia was not achieved and the patient was started on metyrapone treatment before the permanent treatment plan. Postoperative Gallium-68 DOTA PET-CT indicated residual disease and increased uptake in retropharyngeal, bilateral cervical level 2-4, right level 3, bilateral central, and bilateral lower cervical lymph nodes. The persistence of hypercortisolemia after surgery was most likely attributed to residual disease, however, it was considered that pituitary adenoma may also be the cause of ACTH secretion. Therefore, to confirm the source of ACTH secretion, ACTH washout samples were taken from the cervical lymph nodes and were found to be high as 958 ng/L. Reoperation was performed for recurrent mass and lymph node metastases. Conclusion: Medullary thyroid cancer should definitely be considered in cases of ectopic ACTH syndrome. ACTH washing from the suspected lymph node may be an option for diagnostic purposes. In addition to the patient's primary tumor, hypercortisolism should also be treated. Table 1. Cushing's assessment tests [ABSTRACT FROM AUTHOR]- Published
- 2024
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29. Subklinik ve Aşikar Hipotiroidinin Plazma Oksisiterol Türevleri Üzerine Etkisi
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Uğur Ünlütürk, Savaş, Merve, Oğuz, Seda Baykal, Samadi, Afshin, İncilay Lay, Gürlek, Alper, Hacettepe Tıp Fakültesi, Endokrinoloji Ve Metabolizma, Hastalıkları Bd, and Tıbbi Biyokimya
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- 2017
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30. Treatment of acromegaly by endoscopic transsphenoidal surgery: surgical experience in 214 cases and cure rates according to current consensus criteria
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Hazer, Derya Burcu, primary, Işık, Serhat, additional, Berker, Dilek, additional, Güler, Serdar, additional, Gürlek, Alper, additional, Yücel, Taşkın, additional, and Berker, Mustafa, additional
- Published
- 2013
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31. Early promising results for the endoscopic surgical treatment of Cushing’s disease
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Berker, Mustafa, primary, Işikay, Ilkay, additional, Berker, Dilek, additional, Bayraktar, Miyase, additional, and Gürlek, Alper, additional
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- 2013
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32. Chemerin is not associated with subclinical atherosclerosis markers in prediabetes and diabetes.
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Aydın, Kadriye, Canpolat, Uğur, Akına, Şafak, Dural, Muhammet, Karakaya, Jale, Aytemir, Kudret, Özer, Necla, and Gürlek, Alper
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CHEMERIN ,ATHEROSCLEROSIS ,ADIPOKINES ,GLUCOSE metabolism ,BRACHIAL artery ,METABOLIC syndrome - Abstract
Objective: Chemerin is a novel adipokine that is correlated with adipocyte differentiation, glucose metabolism, and inflammation. We aimed to investigate the relation between serum chemerin level and subclinical atherosclerosis markers as exemplified by brachial artery pulse wave velocity (baPWV), carotid intima-media thickness (CIMT), epicardial fat thickness (EFT), and carotid plaque presence in diabetes and prediabetes. Methods: Age-, body mass index (BMI)-, and gender-matched patients with type 2 DM (n=30), prediabetes (n=25), and normal glucose tolerance (n=25) were included in this cross-sectional study. Serum chemerin level, lipid parameters, glucose metabolism marker, baPWV, CIMT, EFT, and anthropometric were recorded. The independent risk factors for atherosclerosis markers were determined by linear and/or multiple logistic regression analysis. Results: baPWV and carotid plaque presence were higher in the diabetes group than in prediabetes and control groups (p=0.039 and p=0.035 respectively), whereas serum chemerin levels were similar among groups (p=0.338). Chemerin levels were not correlated with PWV, CIMT, and epicardial fat thickness overall or in the subgroups. Overall and in the diabetes group, chemerin levels were positively correlated with the key components of metabolic syndrome as BMI, total body fat percentage, waist circumference, triglyceride, and systolic and diastolic blood pressure (BP). After adjusting for age, gender, and BMI, only the association between chemerin and systolic BP remained significant. Chemerin was not found as an independent risk factor for predicting atherosclerosis in diabetes and prediabetes. Conclusion: Chemerin is not a predictive marker for atherosclerosis in diabetes and prediabetes, but correlates well with key aspects of the metabolic syndrome particularly in diabetes. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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33. Pigment epithelium-derived factor increases in type 2 diabetes after treatment with metformin
- Author
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Akın, Şafak, primary, Aksoy, Duygu Yazgan, additional, Çınar, Neşe, additional, Aydın, Kadriye, additional, Karaağaoğlu, Ergun, additional, Arıyürek, Macit, additional, Gülçelik, Neşe Ersöz, additional, Usman, Aydan, additional, and Gürlek, Alper, additional
- Published
- 2012
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34. Complications of endoscopic surgery of the pituitary adenomas: analysis of 570 patients and review of the literature
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Berker, Mustafa, primary, Hazer, Derya Burcu, additional, Yücel, Taşkın, additional, Gürlek, Alper, additional, Cila, Ayşenur, additional, Aldur, Mustafa, additional, and Önerci, Metin, additional
- Published
- 2011
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35. Serum vaspin levels in hypothyroid patients
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Çinar, Neşe, primary, Gülçelik, Neşe Ersöz, additional, Aydín, Kadriye, additional, Akín, Şafak, additional, Usman, Aydan, additional, and Gürlek, Alper, additional
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- 2011
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36. Bazal Hücreli Karsinomda Histolojik Özelliklerin Nüks ve İyileşmeye Etkileri
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Karaca, Can, Görgü, Metin, Erdoğan, Bülent, Gürlek, Alper, Aköz, Tayfun, Kulaçoğlu, Sezer, Maltepe Üniversitesi, Tıp Fakültesi, and Aköz, Tayfun
- Subjects
Bas al Celi ca ,Recurrence ,Nüks ,Bazal hücreli Ca - Abstract
Nisan 1987 ile Aralık 1990 tarihleri arasında kliniğimizde tedavi edilen baş boyun bölgesindeki 162 bazal hücreli karsinom olgusu etyolojik faktörler, lezyonun yeri, büyüklüğü, süresi ve görünüm özellikleri, açısından değerlendirildi Spesmeulerde histolojik tiplendirme yapıldı ve lezyonların mikroskapik özellikleri belirlendi. Olgular 1-3-6 aylık aralarla en az 3 yıl takip edildi. Cerrahi sınırda tümör varlığı, histolojik lip ve mikroskopik özelliklerin nüks ve iyileşmeye etkisi değerlendirildi., W e revievıed 162 e as es of he ad and ne ek bas al celi Ca ıvhich had, heen operated betıueen April 1987-December 1990, and evaluated location, size, etiologic factors, appearance and duration ofthe lesıons. Microscopic characteristics of lesions w ere defined after histopathologic evaiuatıon of the specimens. Cases luere folloıued-up minimally 3 years mith 1-3-6 months irderuals. VVk evaluated the effects of posildve-margin lumor, his topa t. hologıc type and. microsopic characteristics on recurrmce.
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- 1994
37. Evaluation of subclinical coronary atherosclerosis in mild asymptomatic primary hyperparathyroidism patients
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Kepez, Alper, primary, Harmanci, Ayla, additional, Hazirolan, Tuncay, additional, Isıldak, Mehlika, additional, Kocabas, Ugur, additional, Ates, Ahmet, additional, Ciftci, Orcun, additional, Tokgozoglu, Lale, additional, and Gürlek, Alper, additional
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- 2008
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38. Pregnancy-induced severe gestational hyperlipidemia mimicking familial hyperlipidemia
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Basaran, Ahmet, primary, Dağdelen, Selçuk, additional, Gürlek, Alper, additional, Bozdağ, Gürkan, additional, and Beksaç, Sinan, additional
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- 2008
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39. What are the markers of aggressiveness in prolactinomas? Changes in cell biology, extracellular matrix components, angiogenesis and genetics
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Gürlek, Alper, primary, Karavitaki, Niki, additional, Ansorge, Olaf, additional, and Wass, John A H, additional
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- 2007
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40. Global assessment of the coagulation status in type 2 diabetes mellitus using rotation thromboelastography
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Yürekli, Banu Pinar Sarer, primary, Özcebe, Osman Ilhami, additional, Kirazli, Serafettin, additional, and Gürlek, Alper, additional
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- 2006
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41. Increased asymmetric dimethylarginine (ADMA) levels and decreased homocysteine thiolactonase/paraoxonase (HTLase/PONase) activities are related to the risk of cardiovascular disease in prediabetic/diabetic patients.
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Bayrak, Tülin, Bayrak, Ahmet, Işıldak, Mehlika, Çakır, Erdinç, Gürlek, Alper, and Akbıyık, Filiz
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ASYMMETRIC dimethylarginine ,PEOPLE with diabetes ,DIABETES ,PARAOXONASE ,HOMOCYSTEINE - Abstract
Copyright of Turkish Journal of Biochemistry / Turk Biyokimya Dergisi is the property of De Gruyter and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2014
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42. Effect of Endogenous Subclinical Hyperthyroidism on Bone Metabolism and Bone Mineral Density in Premenopausal Women
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GÜRLEK, ALPER, primary and GEDIK, OLCAY, additional
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- 1999
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43. QT dispersion and autonomic nervous system function in patients with type 1 diabetes
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Aytemir, Kudret, primary, Aksöyek, Serdar, additional, Özer, Necla, additional, Gürlek, Alper, additional, and Oto, Ali, additional
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- 1998
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44. Altered Red Blood Cell Rheology as a Predisposing Factor for Diabetic Nephropathy
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Demiroglu, Halûk, primary and Gürlek, Alper, additional
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- 1998
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45. Liver Tests in Hyperthyroidism: Effect of Antithyroid Therapy
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Gürlek, Alper, primary, Çobankara, Veli, additional, and Bayraktar, Miyase, additional
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- 1997
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46. A Miracle of Salamization: Positive Divided by Two Equals Negative
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Gürlek, Alper, primary and Özdemir, Oktay, additional
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- 1997
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47. Relationship Between Increased Serum Lipoprotein (a) Levels and Urinary Albumin Excretion in NIDDM Patients
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BAYRAKTAR, Miyase, primary, SAYINALP, Sabri, additional, GÜRLEK, Alper, additional, and GEDİK, Olcay, additional
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- 1997
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48. Alterations in Liver Biochemical Tests at Diagnosis and After Propylthiouracil Therapy in Hyperthyroidism
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GÜRLEK, Alper, primary, ÇOBANKARA, Veli, additional, and BAYRAKTAR, Miyase, additional
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- 1996
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49. ISOLATED ADRENOCORTICOTROPIC HORMONE DEFICIENCY, THYROID AUTOIMMUNITY, AND TRANSIENT HYPERPROLACTINEMIA
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Gürlek, Alper, Nar, Asli, and Gedik, Olcay
- Abstract
Objective: To describe a case of isolated adrenocorticotropic hormone (ACTH) deficiency associated with thyroid autoimmunity, subclinical hypothyroidism, and transient hyperprolactinemia. Methods: We present a detailed case report, including results of laboratory studies and magnetic resonance imaging, and discuss potential contributing factors in this setting. Results: In a 23-year-old woman with isolated ACTH deficiency accompanied by thyroid autoimmunity (Hashimoto's thyroiditis), subclinical primary hypothyroidism, and hyperprolactinemia, magnetic resonance imaging of the pituitary showed normal findings but dynamic stimulation testing of the pituitary gland indicated an isolated ACTH deficiency with intact growth hormone and gonadotropin secretory reserves. The cortisol response to the short ACTH stimulation test was subnormal. Therapy with prednisolone (5 mg/day) and levothyroxine (100 mg/day) was initiated. Results of thyroid function tests were normalized after 1 month, the prolactin level decreased to normal after 1 year, and titers of thyroid autoantibodies decreased substantially after 1.5 years of treatment. Conclusion: The correction of the related glucocorticoid deficiency resulted in resolution of the hyperprolactinemia and a decrease in titers of thyroid autoantibodies.
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- 2001
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50. 35th Annual Meeting of the European Association for the Study of Diabetes
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Melander, A., Olsson, J., Lindberg, G., Salzman, A., Howard, T., Stang, P., Lydick, E., Emslie-Smith, A., Boyle, D. I. R., Evans, J. M. M., Macdonald, T. M., Bain, J., Sullivan, F., Juhl, C., Pørksen, N., Sturis, J., Hollingdal, M., Pincus, S., Veldhuis, J., Dejgaard, A., Schmitz, O., Kristensen, J. S., Frandsen, K. B., Bayer, Th., Müller, P., Dunning, B. E., Paladini, S., Gutierrez, C., Deacon, R., Valentin, M., Grunberger, G., Weston, W. M., Patwardhan, R., Rappaport, E. B., Sargeant, L. A., Wareham, N. J., Khaw, K. T., Zethelius, Björn, Lithell, Hans, Hales, C. Nicholas, Berne, Christian, Lakka, H.-M., Oksanen, L., Tuomainen, T.-P., Kontula, K., Salonen, J. T., Dekker, J. M., de Boks, P., de Vegt, F., Stehouwer, C. D. A., Nijpels, G., Bouter, L. M., Heine, R. J., Bruno, G., Cavallo-Perin, P., Bargero, G., D’Errico, N., Borra, M., Macchia, G., Pagano, G., Newton, R. W., Ruta, D. A., New, J. P., Wallace, C., Roxburgh, M. A., Young, R. J., Vaughan, N. J. A., Elliott, P., Brennan, G., Devers, M., MacAlpine, R., Steinke, D., Lawson, D. H., Decallonne, B., Casteels, K., Gysemans, C., Bouillon, R., Mathieu, C., Linn, Thomas, Strate, Christine, Schneider, Kerstin, Funda, D. P., Jirsa, M., Kozáková, H., Kaas, A., Kofronová, O., Tlaskalová-Hogenová, H., Buschard, K., Wanka, H., Hartmann, A., Kuttler, B., Rasmussen, S. B., Sørensen, T. S., Markholst, H., Petersen, J. S., Karounos, D., Dyrberg, T., Mabley, J. G., Haskó, G., Szabó, C., Seissler, J., Nguyen, T. B. T., Steinbrenner, H., Scherbaum, W. A., Cipriani, R., Gabriele, A., Sensi, M., Guidobaldi, L., Pantellini, F., Cerrito, M. G., Scarpa, S., Di Mario, U., Morano, S., Ceolotto, G., Iori, E., Baritono, E., Del Prato, S., Semplicini, A., Trevisan, R., Zerbini, G., Meregalli, G., Asnaghi, V., Tentori, F., Maestroni, A., Mangili, R., Marescotti, C., Vedovato, M., Tiengo, A., Tadjieva, J., Mankovsky, B. N., Van Aken, S., Raes, A., Vande Walle, J., Matthys, D., Craen, M., Hansen, H. P., Lund, S. S., Rossing, P., Jensen, T., Parving, H.-H., Andersen, S., Tarnow, L., Hansen, B. V., Trautner, C., Haastert, B., Ennenbach, N., Willich, S., Tabák, Á. Gy., Orchard, T. J., Spranger, J., Preissner, K. T., Schatz, H., Pfeiffer, A., Cantón, A., Burgos, R., Hernández, C., Lecube, A., Mesa, J., Segura, R. M., Mateo, C., Simó, R., Fathallah, L., Greene, D. A., Obrosova, I., Gilbert, R. E., Kelly, D. J., Cox, A. J., Berka-Wilkinson, J. L., Taylor, H. R., Panagiotopoulos, S., Lee, V., Jerums, G., Cooper, M. E., Hitman, G. A., Aganna, E., Ogunkolade, W. B., Rema, M., Deepa, R., Shanthi-Rani, C. S., Barakat, K., Kumarajeewa, T. R., Cassell, P. G., McDermott, M. F., Mohan, V., Ways, K., Bursell, S., Devries, T., Woodworth, J., Alatorre, C., King, G., Aiello, L. P., Karisen, A. E., Pavlovic, D., Nielsen, K., Jensen, J., Andersen, H. U., Pociot, F., Mandrup-Poulsen, T., Eizirik, D. L., Nerup, J., Lortz, S., Tiedge, M., Lenzen, S., Lally, F. J., Bone, A. J., Darville, M. I., Ho, Y.-S., Sternesjö, J., Sandler, S., Chen, M.-C., Schuit, F., Pipeleers, D. G., Merezak, S., Hardikar, A., Hoet, J. J., Remacle, C., Reusens, B., Bréant, B., Garofano, A., Czernichow, P., Kubota, N., Terauchi, Y., Miki, H., Tamemoto, H., Yamauchi, T., Nakano, R., Komeda, K., Eto, K., Tobe, K., Kimura, S., Kadowaki, T., Ide, T., Murakami, K., Tsunoda, M., Mochizuki, T., Ozanne, S. E., Nave, B. T., Wang, C. L., Dorling, M. W., Petry, C. J., Koopmans, S. J., van der Bent, C., Que, I., Radder, J. K., Sebokova, E., Sana, A. K., Klimes, I., Ruderman, N., Morviducci, L., Pastore, L., Morelli, S., Sagratella, E., Zorretta, D., Buongiomo, A., Tamburrano, G., Giaccari, A., Martinenghi, Sabina, De Angelis, Gabriella Cusella, Ravasi, Flavio, Bifari, Francesco, Bordignon, Claudio, Falqui, Luca, Kessler, A., Dransfeld, O., Sasson, S., Tomas, E., Zorzano, A., Eckel, J., Thorsby, P., Rosenfalck, A. M., Kjems, L., Hanssen, K. F., Madsbad, S., Birkeland, K. I., Hamilton-Wessler, M., Markussen, J., Bergman, R. N., Melki, V., Hanaire-Broutin, H., Bessières-Lacombe, S., Tauber, J.-P., Home, P. D., Lindholm, A., Riis, A., Rosenstock, J., Schwartz, S., Clark, C., Edwards, M., Donley, D., Swift, P., Mortensen, H. B., Lynggaard, H., Hougaard, P., Cull, C. A., Neil, H. A. W., Frighi, V., Manley, S. E., Holman, R. R., Turner, R. C., Steiner, G., Davis, W. A., Weeraratna, T., Bruce, D. G., Davis, T. M. E., Vergès, B., Duvillard, L., Pont, F., Florentin, E., Gambert, Ph., Benko, B., Ljubić, S., Turk, Z., Granić, M., März, W., Wollschläger, H., Klein, G., Neiss, A., Wehling, M., Huxtable, S. J., Saker, P. J., Walker, M., Frayling, T. M., Levy, J. C., O’Rahilly, S., Hattersley, A. T., McCarthy, M. I., Orecchio, A., Giacchini, A., Dominici, R., Canettieri, G., Trinti, B., Zani, M., Andreoli, M., Sciacchitano, S., de Silva, A. M., Whitecross, K., Pasco, J., Kotowicz, M., Nicholson, G., Zimmet, P., Boyko, E. J., Collier, G. R., Frittitta, L., Pizzuti, A., Argiolas, A., Graci, S., Goldfine, I. D., Bozzali, M., Ercolino, T., Costanzo, B., Iacoviello, L., Tassi, V., Trischitta, V., Wauters, M., Rankinen, T., Mertens, I., Chagnon, M., Bouchard, C., Van Gaal, L., Sivenius, K., Valve, R., Hakkarainen, V., Niskanen, L., Laakso, M., Uusitupa, M., Beridze, N., Japaridze, M., Kurashvili, R., Dundua, M., Kebuladze, G., Kazakhashvili, N., Offley-Shore, B., Thomas, B., Ghebremeskel, K., Crawford, M., Lowy, C., Eriksson, Ulf J., Martin Simán, C., Wisse, Bert, Gittenberger-de Groot, Adriana C., Wentzel, P., Eriksson, U. J., Wender-Ożegowska, E., Drews, K., Biczysko, R., Bronisz, A., Rość, D., Graczykowska-Koczorowska, A., Kotschy, M., Sokup, A., Kohnert, K. D., Besch, W., Strese, J., Frick, U., Zander, E., Kemer, W., Škrha, J., Kvasnička, J., Kalvodová, B., Hilgertová, J., Schatteman, K., Goossens, F., Scharpé, S., De Leeuw, I., Hendriks, D., Legakis, I. N., Panayiotou, D., Mountokalakis, Th. D., Enderle, M. D., Beckmann, P., Balletshofer, B., Rittig, K., Maerker, E., Volk, A., Meisner, C., Jacob, S., Matthaei, S., Häring, H. U., Rett, K., Ueda, K., Nakagawa, T., Shimajiri, Y., Kokawa, M., Matsumoto, E., Sasaki, H., Sanke, T., Nanjo, K., McKinnon, Caroline M., Macfarlane, Wendy M., Docherty, Kevin, Furukawa, N., Shirotani, T., Kishikawa, H., Kaneko, K., Araki, E., Shichiri, M., Prentki, M., Roduit, R., Susini, S., Buteau, J., Ejrnæs, A. M., Andersen, N. Aa., Osterhoff, M., Möhlig, M., Ortmann, J., Bikashaghi, F., Mayer, C., Bikashagi, F., Ackermans, M. T., Pereira Arias, A. M., Bisschop, P. H. L. T., Endert, E., Sauerwein, H. P., Romijn, J. A., Gastaldelli, A., Baldi, S., Pettiti, M., Natali, A., Frascerra, S., Camastra, S., Toschi, E., Ferrannini, E., Stingl, H., Krssak, M., Bischof, M. G., Krebs, M., Fürnsinn, C., Nowotny, P., Waldhäusl, W., Roden, M., Neeft, M., Meijer, A. J., Båvenholm, P., Pigon, J., Efendic, S., Kästenbauer, T., Sauseng, S., Sokol, G., Auinger, M., Irsigler, K., Abbott, C. A., Carrington, A. L., Faragher, B., Kulkarni, J., Van Ross, E. R. E., Boulton, A. J. M., Armstrong, D. G., Hadi, S., Nguyen, H. C., Harkless, L. B., Jirkovská, A., Kasalicky, P., Hosová, J., Skibova, J., Uccioli, L., Caselli, A., Giacomozzi, C., Macellari, V., Giurato, L., Lardieri, L., Menzinger, G., Pham, H. T., Rosenblum, B. I., Lyons, T. E., Giurini, J. M., Smakowski, P., Chrzan, J. S., Habershaw, G. M., Veves, A., Foster, A. M., Bates, M., Doxford, M., Edmonds, M. E., Kecha, O., Winkler, R., Martens, H., Collette, J., Lefèbvre, P. J., Greiner, D., Geenen, V., Atlan-Gepner, C., Naspetti, M., Valéro, R., Barad, M., Lepault, F., Vialettes, B., Naquet, P., de Galan, B., Netea, M. G., Hancu, N., Smits, P., Van der Meer, J. W. M., Osterbye, T., Jørgensen, K. H., Tranum-Jensen, J., Fredman, P., Høy, M., Bokvist, K., Olsen, H. L., Horn, T., Gromada, J., Laub, R., Lohmann, T., Hahn, H. J., Adler, T., Emmrich, F., Rabuazzo, A. M., Lupi, R., Dotta, F., Patanè, G., Marselli, L., Realacci, M., Piro, S., Del Guerra, S., Santangelo, C., Navalesi, R., Purrello, F., Marchetti, P., de Vos, P., Visser, L., de Haan, B. J., Klok, P., van Schilfgaarde, R., Poppema, S., Juang, J.-H., Kuo, C.-H., Hsu, B. R.-S., Nacher, V., Pérez, M., Biarnés, M., Raurell, M., Soler, J., Montanya, E., Ritzel, R., Maubach, J., Büsing, M., Becker, T., Klempnauer, J., Hücking, K., Schmiegel, W. H., Nauck, M. A., Bouček, P., Saudek, F., Adamec, M., Kožitarová, R., Jedináková, T., Vlasáková, Z., Skibová, J., Bartoš, V., Maffi, P., Bertuzzi, F., Aldrighetti, L., Taglietti, M. V., Castelnuovo, A., Pozza, G., Di Carlo, V., Secchi, A., Renier, G., Mamputu, J.-C., Gillespie, J. S., McMaster, D., Mercer, C., Trimble, E. R., Lecomte, M., Véricel, E., Paget, C., Ruggiero, D., Lagarde, M., Wiernsperger, N., Pricci, F., Leto, G., Amadio, L., Cordone, S., Iacobini, C., Catalano, S., Violi, F., Rotella, C. M., Pugliese, G., Zicari, A., Gradini, R., Sale, P., Pala, L., Cresci, B., Giannini, S., Manuelli, C., Dahlfors, G., Arnqvist, H. J., Gonelle-Gispert, C., Halnan, P. A., Sadoul, K., Wolter, S., Lang, J., Niwa, T., Yu, W., Hidaka, H., Senda, T., Niki, I., Fukasawa, T., Renstrom, E., Barg, S., Seward, E., Rorsman, P., Rutter, G. A., Molinete, M., Lilla, V., Ravazzola, M., Halban, P. A., Efanov, A. M., Bertorello, A. M., Zaitsev, S. V., Zwiller, J., Berggren, P.-O., MŞengül, A., Salman, F., Sargrn, M., Özer, E., Karşidaǧ, K., Salman, S., Gedik, S., Satman, İ., Dinççaǧ, N., Yılmaz, M. T., Lloyd, A., Hopkinson, P. K., Testa, M. A., Blonde, L., Turner, R. R., Hayes, J., Simonson, D. C., van der Ven, N. C. W., Lubach, C. H. C., Snoek, F. J., Mollema, E. D., van der Ploeg, H. M., Danne, T., Hoey, H., McGee, H., Fitzgerald, H., Lernmark, B., Thernlund, G., Fredin, K., Hägglöf, B., Lugari, R., Dell’Anna, C., Ugolotti, D., Dei Cas, A., Barilli, A. L., Sard, L., Marani, B., Iotti, M., Zandomeneghi, R., Gnudi, A., Kjems, L. L., Volund, Aa., Toft-Nielsen, M., Damholt, M. B., Hilsted, L., Hughes, T. E., Krarup, T., Holst, J. J., Young, A., Gottlieb, A., Fineman, M., Kolterman, O., Cancelas, J., García-Martínez, J. A., Villanueva-Peñacarrillo, M. L., Valverde, I., Malaisse, W. J., Filipsson, K., Ahrén, B., Balkan, B., Kwasnik, L., Battle, B., Li, X., Egan, J. M., Clocquet, A. R., Elahi, D., Petrella, E., Pricket, K., Petersen, K. F., Sullivan, J. T., Amatruda, J. M., Livingston, J. N., Shulman, G. I., Freyse, E.-J., Knospe, S., Glund, K., Demuth, H.-U., Walker, D., Malik, R. A., Reljanovic, M., Barada, A., Milicevic, Z., Tack, Cees J., Goldstein, David S., Van Huysen, C., Stevens, M. J., Cao, X., Sundkvist, G., Dahlin, L.-B., Eriksson, K.-F., Rosén, I., Lattimer, S. A., Sima, A. A. F., Sullivan, K., Shaw, J. E., de Courten, M. P., Zimmet, P. Z., Gourdy, P., Ruidavets, J. B., Arveiler, D., Amouyel, Ph., Bingham, A., Tauber, J. P., Lam, K. S. L., Wat, N. M. S., Lam, T. H., Janus, E. D., de Pablos, P., Rodriguez, F., Martínez, J., Sánchez, V., Santana, C., García, I., Macías, A., Levin, K., Hother-Nielsen, O., Henriksen, J. E., Beck-Nielsen, H., Brechtel, K., Machann, J., Koch, M., Nielsen, M., Löblein, K., Becker, R., Denignger, M., Renn, W., Machicao, F., Claussen, C. D., Schick, F., Diraison, F., Moulin, P., Beylot, M., Thams, P., Capito, K., Eliasson, Lena, Barg, Sebastian, Göpel, Sven, Kanno, Takahiro, Renström, Erik, Meda, P., Charollais, A., Gjnovci, A., Calabrese, A., Wonkam, A., Caton, D., Wisznievski, L., Serre, V., Cogne, F., Bauquis, J., Bosco, D., Huarte, J., Herrera, P., Gotfredsen, C. F., Vessby, B., Manuel y Keenoy, B., Engelen, W., Vertommen, J., Schrans, S., Louheranta, A., Lindström, J., Tuomilehto, J., Segal, K. R., Heymsfield, S., Hauptman, J., Boldrin, M., Lucas, C., Pandolfi, A., Cetrullo, D., Polishchuck, R., Alberta, M., Pellegrini, G., Calafiore, A., Vitacolonna, E., Capani, F., Consoli, A., Halleux, C. M., Gillot, E. F., Brichard, S. M., Van der Planken, M., Corthouts, B., Peiffer, F., Scholten, D., Walke, M., Assert, R., Pirags, V., Pedula, K. L., Hillier, T. A., Brown, J. B., Santini, S. A., Marra, G., Cotroneo, P., Manto, A., Di Leo, M. A. S., Di Gregorio, S., Tordi, A., Pitocco, D., Ruotolo, V., Ghirlanda, G., Temelkova-Kurktschiev, T., Schaper, F., Koehler, C., Henkel, E., Hanefeld, M., Mancini, L., Citterio, F., Cotroneo, A., Ceroone, S., Castagneto, M., Rajbhandari, S. M., Dent, M. T., Plater, M. E., Harris, N. D., Tesfaye, S., Ward, J. D., Dupuy, O., Mayaudon, H., Lecoules, S., Bauduceau, B., Palou, M., Farret, O., Molinié, C., Antonelli-Incalzi, R., Fuso, L., Giordano, A., Calcagni, M. L., Todaro, L., Basso, S., Tramaglino, L. M., Troncone, L., Pistelli, R., Guillot, R., Bringuier, A., Porokhov, B., Guillausseau, P. J., Feldmann, G., Zivanic, S., Cizmic, M., Dragojevic, R., Vanovic, M., Borghouts, L. B., van Kranenburg, G. P. J., Schaart, G., Keizer, H. A., Niess, A. M., Dickuth, H. H., Lutz, O., Barbe, P., Calazel-Fournier, C., Hernandez, G., Saint-Martin, F., Galitzky, J., Gonçalves, A. A., da Silva, E. C., Brito, I. J. L., da Silva, C. A., Lawrence, N. J., Kousta, E., Mulnier, H., Penny, A., Millauer, B., Johnston, D. G., Robinson, S., Perriello, G., Pimenta, W., Pampanelli, S., Lucidi, P., Lepore, M., Porcellati, F., Cordoni, M. C., De Feo, P., Bolli, G. B., Sjöstrand, M., Holmäng, A., Lönnroth, P., Hauer, B., Grauer, P., Artzner, S., Lang, R., Stumvoll, M., Monti, L. D., Piatti, P. 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- 1999
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