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4 results on '"G. Shopayeva"'

1. The burden and epidemiology of community-acquired central nervous system infections: a multinational study

Author

Recep Tekin, Lenka Baštáková, Alexandru Crisan, Nenad Pandak, Egidia Miftode, C. Jekkel, Ejaz Ahmed Khan, Eva Pernicová, Serhat Uysal, A. Jouhar, Xavier Argemi, Rodrigo Hasbun, A. Pinto, Ugur Musabak, M. Amsilli, Emre Güven, Nefise Oztoprak, L. Čalkić, Arjan Harxhi, M. Momen-Heravi, R. V. Moroti, Hasip Kahraman, Svjetlana Grgić, Ghaydaa A. Shehata, G. Shopayeva, Oğuz Reşat Sipahi, Lykke Larsen, Sally Hargreaves, B. Jegorović, R. Stebel, Z. Fehér, Hakan Erdem, Yasemin Cag, Lurdes Santos, F. Moradi, A. Bruzsa, K. C. Lung, Phillip Chan, Gülden Ersöz, Ljiljana Betica Radić, Soner Yilmaz, F. Rigo, Sadie Namani, Figen Kaptan, Maiya Konkayeva, A. Duissenova, Antonio Cascio, Sholpan Kulzhanova, Hava Yilmaz, B. Utaganov, M. Baldeyrou, T. Tang, Humera Porobic-Jahic, Fatma Yilmaz-Karadag, Sead Ahmetagic, M. Nassar, J. Aron, Asuman Inan, B. Lakatos, Hanefi Cem Gul, Anne Lisbeth Bohr, G. Bellaud, Cumhur Artuk, Ahmad Khalifa, A. Canestri, İlhami Çelik, Zauresh Smagulova, A. Moravveji, A. K. L. Wu, L. Praticò, T. Roganović, Lucrecia Salazar, M. Lanzafame, P. Bossi, Selçuk Kaya, Virulence Bactérienne Précoce : fonctions cellulaires et contrôle de l'infection aigüe et subaigüe, Université de Strasbourg (UNISTRA), Erdem, H., Inan, A., Guven, E., Hargreaves, S., Larsen, L., Shehata, G., Pernicova, E., Khan, E., Bastakova, L., Namani, S., Harxhi, A., Roganovic, T., Lakatos, B., Uysal, S., Sipahi, O.R., Crisan, A., Miftode, E., Stebel, R., Jegorovic, B., Fehér, Z., Jekkel, C., Pandak, N., Moravveji, A., Yilmaz, H., Khalifa, A., Musabak, U., Yilmaz, S., Jouhar, A., Oztoprak, N., Argemi, X., Baldeyrou, M., Bellaud, G., Moroti, R.V., Hasbun, R., Salazar, L., Tekin, R., Canestri, A., Čalkić, L., Praticò, L., Yilmaz-Karadag, F., Santos, L., Pinto, A., Kaptan, F., Bossi, P., Aron, J., Duissenova, A., Shopayeva, G., Utaganov, B., Grgic, S., Ersoz, G., Wu, A.K.L., Lung, K.C., Bruzsa, A., Radic, L.B., Kahraman, H., Momen-Heravi, M., Kulzhanova, S., Rigo, F., Konkayeva, M., Smagulova, Z., Tang, T., Chan, P., Ahmetagic, S., Porobic-Jahic, H., Moradi, F., Kaya, S., Cag, Y., Bohr, A., Artuk, C., Celik, I., Amsilli, M., Gul, H.C., Cascio, A., Lanzafame, M., Nassar, M., and Ondokuz Mayıs Üniversitesi

Subjects
0301 basic medicine, Male, Outcome Assessment, Adverse Clinical Outcome, medicine.disease_cause, Central nervous system infections, burden, epidemiology, Medical microbiology, Central Nervous System Infections, Outcome Assessment, Health Care, Epidemiology, 80 and over, Aged, 80 and over, biology, Age Factors, General Medicine, Middle Aged, Community-Acquired Infections, Infectious Diseases, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, Population Surveillance, Female, Neuroborreliosis, Human Immunodeficiency Virus, Microbiology (medical), Adult, medicine.medical_specialty, Tuberculosis, Settore MED/17 - Malattie Infettive, 030106 microbiology, Brain Abscess, Central Nervous System Infection, Neurosyphilis, Mycobacterium tuberculosis, 03 medical and health sciences, Young Adult, Internal medicine, Streptococcus pneumoniae, Journal Article, medicine, Humans, Aged, Retrospective Studies, business.industry, Varicella zoster virus, medicine.disease, biology.organism_classification, Health Care, Cross-Sectional Studies, Central Nervous System Disease, Brain Absce, Human Immunodeficiency Viru, Immunology, business
Abstract

Ghaydaa, Shehata/0000-0002-3631-893X; Radic, Ljiljana Betica/0000-0002-8778-106X; Silva-Pinto, Andre/0000-0002-2077-3356; Cascio, Antonio/0000-0002-1992-1796; Bossi, Paolo/0000-0003-0135-0224; Stebel, Roman/0000-0001-6922-4465; Namani, Sadie/0000-0002-2411-8623; Chan, Phillip/0000-0002-4071-4409; Hargreaves, Sally/0000-0003-2974-4348; Artuk, Cumhur/0000-0003-0827-990X; Harxhi, Arjan/0000-0001-8518-7377; Larsen, Lykke/0000-0002-4113-4182; Uysal, Serhat/0000-0002-4294-5999 WOS: 000407582200010 PubMed: 28397100 Risk assessment of central nervous system (CNS) infection patients is of key importance in predicting likely pathogens. However, data are lacking on the epidemiology globally. We performed a multicenter study to understand the burden of community-acquired CNS (CA-CNS) infections between 2012 and 2014. A total of 2583 patients with CA-CNS infections were included from 37 referral centers in 20 countries. Of these, 477 (18.5%) patients survived with sequelae and 227 (8.8%) died, and 1879 (72.7%) patients were discharged with complete cure. The most frequent infecting pathogens in this study were Streptococcus pneumoniae (n = 206, 8%) and Mycobacterium tuberculosis (n = 152, 5.9%). Varicella zoster virus and Listeria were other common pathogens in the elderly. Although staphylococci and Listeria resulted in frequent infections in immunocompromised patients, cryptococci were leading pathogens in human immunodeficiency virus (HIV)-positive individuals. Among the patients with any proven etiology, 96 (8.9%) patients presented with clinical features of a chronic CNS disease. Neurosyphilis, neurobrucellosis, neuroborreliosis, and CNS tuberculosis had a predilection to present chronic courses. Listeria monocytogenes, Staphylococcus aureus, M. tuberculosis, and S. pneumoniae were the most fatal forms, while sequelae were significantly higher for herpes simplex virus type 1 (p < 0.05 for all). Tackling the high burden of CNS infections globally can only be achieved with effective pneumococcal immunization and strategies to eliminate tuberculosis, and more must be done to improve diagnostic capacity.

Published
2017
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2. Evaluation of a PCR test for the diagnosis of Brucella ovis infection in semen samples from rams

Author

Ignacio López-Goñi, Lorea Manterola, José M. Blasco, G Shopayeva, A Tejero-Garcés, Clara Marin, and A Ficapal

Subjects
DNA, Bacterial, Male, Brucella ovis, Immunodiffusion, Sheep Diseases, Semen, Brucellaceae, Brucella, Biology, Microbiology, Polymerase Chain Reaction, Sensitivity and Specificity, Brucellosis, law.invention, Serology, fluids and secretions, law, medicine, Animals, Polymerase chain reaction, Sheep, General Veterinary, Complement Fixation Tests, General Medicine, biology.organism_classification, medicine.disease, Antibodies, Bacterial, DNA Transposable Elements
Abstract

The sensitivity and specificity of a PCR assay with primers derived from the insertion sequence IS6501 was compared with that of bacteriological culture and serological tests for the diagnosis of Brucella ovis infection in rams. No amplifications were detected with DNAs from the strains phylogenetically related to Brucella and from the seven bacterial species considered as the main etiologic agents of epididymitis in rams. In addition, the specificity of the PCR was 100% when testing semen samples from Brucella-free rams. The comparison of the semen culture and PCR results from 192 semen samples tested, showed a proportion of agreement of 0.91 between both tests. The PCR-based test described has sensitivity similar to that of semen culture and could be used as a complementary test for the direct diagnosis of Brucella ovis in semen samples of rams.

Published
2002

3. The burden and epidemiology of community-acquired central nervous system infections: a multinational study.

Author

Erdem H, Inan A, Guven E, Hargreaves S, Larsen L, Shehata G, Pernicova E, Khan E, Bastakova L, Namani S, Harxhi A, Roganovic T, Lakatos B, Uysal S, Sipahi OR, Crisan A, Miftode E, Stebel R, Jegorovic B, Fehér Z, Jekkel C, Pandak N, Moravveji A, Yilmaz H, Khalifa A, Musabak U, Yilmaz S, Jouhar A, Oztoprak N, Argemi X, Baldeyrou M, Bellaud G, Moroti RV, Hasbun R, Salazar L, Tekin R, Canestri A, Čalkić L, Praticò L, Yilmaz-Karadag F, Santos L, Pinto A, Kaptan F, Bossi P, Aron J, Duissenova A, Shopayeva G, Utaganov B, Grgic S, Ersoz G, Wu AKL, Lung KC, Bruzsa A, Radic LB, Kahraman H, Momen-Heravi M, Kulzhanova S, Rigo F, Konkayeva M, Smagulova Z, Tang T, Chan P, Ahmetagic S, Porobic-Jahic H, Moradi F, Kaya S, Cag Y, Bohr A, Artuk C, Celik I, Amsilli M, Gul HC, Cascio A, Lanzafame M, and Nassar M

Subjects
Adult, Age Factors, Aged, Aged, 80 and over, Central Nervous System Infections etiology, Central Nervous System Infections mortality, Community-Acquired Infections etiology, Community-Acquired Infections mortality, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Outcome Assessment, Health Care, Retrospective Studies, Young Adult, Central Nervous System Infections epidemiology, Community-Acquired Infections epidemiology, Population Surveillance
Abstract

Risk assessment of central nervous system (CNS) infection patients is of key importance in predicting likely pathogens. However, data are lacking on the epidemiology globally. We performed a multicenter study to understand the burden of community-acquired CNS (CA-CNS) infections between 2012 and 2014. A total of 2583 patients with CA-CNS infections were included from 37 referral centers in 20 countries. Of these, 477 (18.5%) patients survived with sequelae and 227 (8.8%) died, and 1879 (72.7%) patients were discharged with complete cure. The most frequent infecting pathogens in this study were Streptococcus pneumoniae (n = 206, 8%) and Mycobacterium tuberculosis (n = 152, 5.9%). Varicella zoster virus and Listeria were other common pathogens in the elderly. Although staphylococci and Listeria resulted in frequent infections in immunocompromised patients, cryptococci were leading pathogens in human immunodeficiency virus (HIV)-positive individuals. Among the patients with any proven etiology, 96 (8.9%) patients presented with clinical features of a chronic CNS disease. Neurosyphilis, neurobrucellosis, neuroborreliosis, and CNS tuberculosis had a predilection to present chronic courses. Listeria monocytogenes, Staphylococcus aureus, M. tuberculosis, and S. pneumoniae were the most fatal forms, while sequelae were significantly higher for herpes simplex virus type 1 (p < 0.05 for all). Tackling the high burden of CNS infections globally can only be achieved with effective pneumococcal immunization and strategies to eliminate tuberculosis, and more must be done to improve diagnostic capacity.

Published
2017
Full Text
View/download PDF

4. Evaluation of a PCR test for the diagnosis of Brucella ovis infection in semen samples from rams.

Author

Manterola L, Tejero-Garcés A, Ficapal A, Shopayeva G, Blasco JM, Marin CM, and López-Goñi I

Subjects
Animals, Antibodies, Bacterial blood, Brucella genetics, Brucellosis diagnosis, Brucellosis microbiology, Complement Fixation Tests, DNA Transposable Elements genetics, DNA, Bacterial chemistry, DNA, Bacterial genetics, Immunodiffusion, Male, Polymerase Chain Reaction methods, Sensitivity and Specificity, Sheep, Sheep Diseases diagnosis, Brucella isolation & purification, Brucellosis veterinary, Polymerase Chain Reaction veterinary, Semen microbiology, Sheep Diseases microbiology
Abstract

The sensitivity and specificity of a PCR assay with primers derived from the insertion sequence IS6501 was compared with that of bacteriological culture and serological tests for the diagnosis of Brucella ovis infection in rams. No amplifications were detected with DNAs from the strains phylogenetically related to Brucella and from the seven bacterial species considered as the main etiologic agents of epididymitis in rams. In addition, the specificity of the PCR was 100% when testing semen samples from Brucella-free rams. The comparison of the semen culture and PCR results from 192 semen samples tested, showed a proportion of agreement of 0.91 between both tests. The PCR-based test described has sensitivity similar to that of semen culture and could be used as a complementary test for the direct diagnosis of Brucella ovis in semen samples of rams.

Published
2003
Full Text
View/download PDF

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