1. ReactIRTM Flow Cell - A New Analytical Tool for Continuous FlowvChemical Processing
- Author
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CARTER Catherine, F, Lange, H, LEY Steven, V, BAXENDALE Ian, R, Wittkamp, B, GOODE Jon, G, GAUNT Nigel, L, CARTER Catherine F., LANGE Heiko, LEY Steven V., BAXENDALE Ian R., WITTKAMP Brian, GOODE Jon G., GAUNT Nigel L., CARTER Catherine, F, Lange, H, LEY Steven, V, BAXENDALE Ian, R, Wittkamp, B, GOODE Jon, G, GAUNT Nigel, L, CARTER Catherine F., LANGE Heiko, LEY Steven V., BAXENDALE Ian R., WITTKAMP Brian, GOODE Jon G., and GAUNT Nigel L.
- Abstract
A newly developed ReactIR flow cell is reported as a convenient and versatile inline analytical tool for continuous flow chemical processing. The flow cell, operated with ATR technology, is attached directly into a reaction flow stream using standard OmniFit (HPLC) connections and can be used in combination with both meso- and microscale flow chemistry equipment. The iC IR analysis software (version 4.0) enables the monitoring of reagent consumption and product formation, aiding the rapid optimisation of procedures. Short-lived reactive intermediates can also be observed in situ, giving further mechanistic insight into complex transformations.
- Published
- 2010