1. Small lymphocytic lymphoma of the prostate mimicking a PIRADS 5 lesion that resolved after systemic treatment
- Author
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Fouzia Shakil, John Phillips, David Ambinder, Tiffany H. Wong, Milana Flusberg, and Nathan C. Wong
- Subjects
Prostatic lymphoma ,Pathology ,medicine.medical_specialty ,Prostate biopsy ,Urology ,Chronic lymphocytic leukemia ,Small lymphocytic leukemia ,Lesion ,Prostate cancer ,chemistry.chemical_compound ,Magnetic resonance imaging ,SLL, small lymphocytic lymphoma ,Prostate ,medicine ,CLL, chronic lymphocytic leukemia ,medicine.diagnostic_test ,mpMRI, multiparametric magnetic resonance imaging ,business.industry ,GGG, Gleason grade group ,medicine.disease ,Diseases of the genitourinary system. Urology ,Lymphoma ,PSA, prostate specific antigen ,medicine.anatomical_structure ,Oncology ,PIRADS, prostate imaging reporting and data system ,chemistry ,Ibrutinib ,Adenocarcinoma ,RC870-923 ,medicine.symptom ,business - Abstract
Prostatic PIRADS 4 and 5 lesions on multiparametric MRI typically represent adenocarcinoma with small lymphocytic lymphoma being a rare pathological finding. We report a case of small lymphocytic lymphoma masquerading as PIRADS 4 and 5 lesions with associated lymphadenopathy in a 69-year-old male on active surveillance for low-risk prostate cancer that was subsequently confirmed on targeted and systematic prostate biopsy. Following treatment of lymphoma with ibrutinib, there was complete resolution of the PIRADS lesions on follow-up mpMRI.
- Published
- 2021
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