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Background: The number of children born into a family has a significant impact on a mother's reproductive system's physiological health and overall well-being. Objectives: This study aimed to explore the effective factors in the number of living children (NLC) among married women in Semnan, Iran, with a particular focus on social, cultural, and economic influences. Methods: This cross-sectional study examined the reproductive histories of 600 married women aged 15 to 49 years from Semnan, Iran. Sample size calculations were based on the principal variable, the expected number of children, using PASS software. The women were selected through a multistage random sampling method from health center lists in 2018 (April-October). The data were collected through interview questionnaires and analyzed using the Quasi-Poisson model. Results: The mean (standard deviation [SD]) age at first marriage for mothers (MAM) and fathers was estimated to be 21.02 (4.80) and 25.10 (4.70) years, respectively. Additionally, the mean (SD) values for the number of expected children (NCEX), living children, and the number of pregnancies were 2.19 (0.96), 1.85 (0.81), and 2.15 (1.03), respectively. Among the variables of interest, only NCEX, the number of pregnancies (with a positive effect), MAM, father's education, multiple births, and the desire to have children (with a negative effect) significantly influenced NLC. Conclusions: This study recommends implementing an educational program to promote an optimal and ideal family size to prevent adverse pregnancy outcomes. The age of women at marriage is a significant factor, as an increase in women's age leads to shorter pregnancy intervals, exposing women to complications, such as premature birth, perinatal death, and intrauterine growth restriction. Policymakers should, therefore, encourage early marriages by fostering a culture and providing supportive facilities. [ABSTRACT FROM AUTHOR]

Background: Varenicline tartrate is a new and selective agonist of the nicotinic acetylcholine receptor (nAChR). This systematic review and meta-analysis aimed to determine varenicline efficacy in smoking cessation among hospitalized patients. Methods: We looked through worldwide databases such as Web of Science, Embase, PubMed, Cochrane, and Scopus. Relevant pieces of research published on varenicline efficacy on smoking cessation among hospitalized patients were discovered using proper keywords. The data were analyzed using Stata software version 14 and a random-effects model meta-analysis. Findings: Nine studies were eligible to be included in this study, with a total sample size of 2131. Generally, the point abstinence rate was significantly greater in the varenicline group than in the placebo group at weeks 12 (odds ratio [OR] = 0.59; 95% CI: 053-0.65; P < 0.001), 24 (OR = 0.78; 95% CI: 0.72-0.84; P < 0.001), and 52 (OR = 0.86; 95% CI: 0.80-0.92; P < 0.001). Furthermore, the continuous abstinence rate for weeks 4 (OR = 0.70; 95% CI: 019-0.54; P = 0.000), 12 (OR = 0.26; 95% CI: 019-0.54; P < 0.001), 24 (OR = 0.32; 95% CI: 019-0.53; P < 0.001), and 52 (OR = 0.32; 95% CI: 019-0.54; P < 0.001) was significantly greater in the varenicline group than in the placebo group. Conclusion: According to the high efficacy of varenicline in both short- and long-term smoking settings and considering the importance of smoking cessation in high-risk hospitalized patients, varenicline consumption could be considered as a main smoking cessation strategy in these patients. [ABSTRACT FROM AUTHOR]

Carbon Monoxide (CO) poisoning is one of the most common causes of death in Iran. The present study investigated the indoor and outdoor CO concentrations at hospitals under the supervision of Mazandaran University of Medical Sciences in Sari, Iran. Indoor and outdoor measured CO were conducted over a period of one month during the 2012 winter season in 4 hospital kitchens using a direct measurement device specialized for CO. The average concentrations of CO gas through gas measuring stations were considered at three stations both in and out of the kitchens. The highest and the lowest average concentrations of outdoor CO in Fatemeh Zahra Hospital (about 2 ppm) and Zare Hospital (about 0.33 ppm) were measured respectively. Besides, the highest and the lowest average concentrations of indoor CO were detected in Imam Hospital (as 9.66 ppm) and BuAli Hospital (as7.66 ppm). The highest ratios of I/O (approximately 10 ppm) have been conducted between 8:00 and 9:00a.m. The lowest median concentrations of CO (approximately 8 ppm) between 11:00 and 12:00 a.m. have been measured. Concentrations of CO in all hospitals in this study were significant. This fact shows poorly ventilation of kitchen due to lack of ventilation design engineering. [ABSTRACT FROM AUTHOR]