190 results on '"GICA, Nicolae"'
Search Results
2. Review of: "[Commentary] Impact of Total Mastectomy on the Lymphatic Pathway and the Limitation of PET Imaging in Breast Cancer Surveillance"
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Gica, Nicolae, primary
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- 2024
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3. Review of: "Review: Human papillomavirus (HPV)"
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Gica, Nicolae, primary
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- 2024
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4. Management of Borderline Ovarian Tumors: Series of Case Report and Review of the Literature
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Gica, Nicolae, Mustata, Laura, Botezatu, Radu, Chirculescu, Raluca, Cigaran, Ruxandra, Gica, Corina, Panaitescu, Anca Maria, and Peltecu, Gheorghe
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- 2021
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5. Review of: "[Review Article] Cytomegalovirus Infection"
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Gica, Nicolae, primary
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- 2023
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6. Preconceptional Counseling in Women with Hyperthyroidism.
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Cima, Luminita Nicoleta, Tarna, Mihaela, Martin, Carmen Sorina, Sirbu, Anca Elena, Soare, Iulia, Panaitescu, Anca Maria, Gica, Nicolae, Barbu, Carmen Gabriela, and Fica, Simona
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MEDICAL personnel ,HYPERTHYROIDISM ,PREGNANCY complications ,CONSCIOUSNESS raising ,PREGNANCY outcomes ,THYROID diseases ,THYROID cancer - Abstract
Preconception evaluation of couples wishing to conceive is an important step toward a healthy pregnancy and it is especially important in people with a chronic condition or at genetic risk. The most common endocrine disorders in women at reproductive age are those involving the thyroid gland and it is well recognized that hyperthyroidism (HT), over-function of the thyroid gland, is associated with risks of maternal, fetal, and neonatal complications. The aim of this paper is to review the latest evidence regarding the components of preconception counseling in women with HT that contemplate a pregnancy. We also want to raise awareness among healthcare professionals about the importance of periconceptional counseling in improving pregnancy outcomes and avoid maternal and fetal complications related to thyroid dysfunction. In women with Graves' disease seeking pregnancy, it is essential to discuss all the treatment options along with the associated risks and benefits. Extensive prospective studies are still needed to understand the implications of current recommended strategies for the management of HT in preconception and during pregnancy. [ABSTRACT FROM AUTHOR]
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- 2024
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7. Undetectable hemoglobin in a patient with chronic uterine bleeding
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Gica Nicolae, Plopa Natalia Darii, Cigaran Ruxandra, Mat Corina, Panaitescu Anca Maria, Peltecu Gheorghe, and Balanescu Paul
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Medicine - Published
- 2019
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8. Review of: "Side effects of COVID-19 vaccination in Pakistani population: A cross sectional study"
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Gica, Nicolae, primary
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- 2023
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9. Review of: "Substance use disorder and associated factors at an opioid de-addiction clinic in Western Kenya"
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Gica, Nicolae, primary
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- 2023
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10. Review of: "[Empirical Paper] Product Development of Digital Platform for Mental Health During Pregnancy Period: ‘Get Well Mom’"
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Gica, Nicolae, primary
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- 2023
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11. Microduplication 3p26.3p24.3 and 4q34.3q35.2 Microdeletion Identified in a Patient with Developmental Delay Associated with Brain Malformation
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Cardos, Georgeta, primary, Gica, Nicolae, additional, Gica, Corina, additional, Panaitescu, Anca Maria, additional, Predescu, Mariana, additional, Peltecu, Gheorghe, additional, and Nedelea, Florina Mihaela, additional
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- 2022
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12. Umbilical Cord Prolapse—Interesting CTG Traces
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Botezatu, Radu, primary, Gica, Nicolae, additional, Peltecu, Gheorghe, additional, and Panaitescu, Anca Maria, additional
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- 2022
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13. Preparing for Pregnancy in Women with Systemic Lupus Erythematosus—A Multidisciplinary Approach
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Saulescu, Ioana, primary, Opris-Belinski, Daniela, additional, Balanescu, Andra, additional, Pavel, Bogdan, additional, Gica, Nicolae, additional, and Panaitescu, Anca, additional
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- 2022
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14. Pulmonary Alveolar Proteinosis and Pregnancy: A Review of the Literature and Case Presentation
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Cimpoca Raptis, Brindusa Ana, primary, Panaitescu, Anca Maria, additional, Peltecu, Gheorghe, additional, Gica, Nicolae, additional, Botezatu, Radu, additional, Popescu, Mihaela Roxana, additional, Macri, Anca, additional, Constantin, Ana, additional, and Pavel, Bogdan, additional
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- 2022
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15. Evolving Trends in the Management of Acute Appendicitis During COVID-19 Waves: The ACIE Appy II Study
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Pata, Francesco, Di Martino, Marcello, Podda, Mauro, Di Saverio, Salomone, Ielpo, Benedetto, Pellino, Gianluca, Julio, Abba, Alshamrani, Abdullah, Alturkistani, Abdullah, Alghamdi, Abdulrahman, Almalki, Abdulrahman, Orengia, Adam, Kuvvetli, Adnan, Pisanu, Adolfo, Smith, Adrian, Treviño Figueroa, Adriana Michelle, Nacion, Aeris Jane, Alhazmi, Ahmad, Bouhuwaish, Ahmad, Khalid, Ahmad, Alsufyani, Ahmed, Rubio, Ainhoa Valle, Bavikatte, Akshay, Kumar, Akshay, Jamiri, Al-Radjid, de San Ildefonso Pereira, Alberto, Porcu, Alberto, Sartori, Alberto, Rocca, Aldo, Sretenovic, Aleksandar, Anselmo, Alessandro, De Luca, Alessandro, Charalabopoulos, Alexandros, Tzivanakis, Alexios, Bandin, Alfonso, Nájar, Alfonso, Frontali, Alice, Faisal, Alsulaimani, Roldan, Amaia Martínez, Hamid, Amal, André, Ana, Minaya-Bravo, Ana, Das, Andre, Bondurri, Andrea, Costanzi, Andrea, Lucchi, Andrea, Mihailescu, Andrei, Police, Andrea, Zuchini, Andres Mendoza, Romano, Angela, Iossa, Angelo, Chessa, Antonella, Tromba, Antonella, Castaldi, Antonio, Brillantino, Antonio, Ferronetti, Antonio, Giuliani, Antonio, Ramos-De la Medina, Antonio, Tarasconi, Antonio, Picciariello, Arcangelo, Ioannidis, Argyrios, Leppäniemi, Ari, Rashid, Arshad, Mitul, Ashrarur Rahman, Mehraj, Asif, Laharwal, Asim, Iqbal, Atif, Liarakos, Athanasios, Marinis, Athanasios, de Andrés-Asenjo, Beatriz, Matías-García, Belén, De Simone, Belinda, Creavin, Ben, Stubbs, Ben, Goh, Brian, Jovanovic, Branislav, Sensi, Bruno, Gazia, Carlo, Cerdán, Carlos, Díaz, Carlos Javier Gómez, Chacón, Carlos Petrola, Yánez, Carlos, Faro, Carmelo Lo, Reinke, Caroline, Dominguez, Casandra, Paranjape, Charudutt, Thomas, Charlotte, Fung, Chia Chi, De Lucia, Chiara, Jennifer, Chiu Hiu Fung, Ovalle-Chao, Christian, Guerci, Claudio, Kenington, Cleo, Gica, Corina, Folliero, Cristina, Varela, Cristopher, Popowich, Daniel, Delogu, Daniele, Zigiotto, Daniele, Vinci, Danilo, D’Antonio, Dario, Merlini, David Alessio, Merlini, David, Moro-Valdezate, David, Keller, Deborah, Nicolaescu, Diana Cristiana, Sasia, Diego, Rodas, Edgar, Linardoutsos, Dimitrios, Russello, Domenico, Nájar-Castañeda, Pedro Alfonso, Stavrou, Habil Gregor, Rosso, Edoardo, Saladino, Edoardo, Ricciardi, Edoardo, Smith-Singares, Eduardo, Baili, Efstratia, Douka, Eleftheria, Guaitoli, Eleonora, Francone, Elisa, Vaterlini, Elisa Maria, Pierobon, Elisa Sefora, Morales, Emilio, Ros, Emilio Peña, Benzoni, Enrico, Erdas, Enrico, Pinotti, Enrico, Colás-Ruiz, Enrique, Laterza, Ernesto, Foianini, Esteban, Cardamone, Eugenia, Licardie, Eugenio, Marino, Fabio, Alsofyani, Fahad, Qahtani, Fahad, Khan, Farhan, Maraska, Fatlum, Saliu, Fatmir, Madrid, Fausto, Rosa, Fausto, Luvisetto, Federico, Alconchel, Felipe, Pareja-Ciuro, Felipe, Neves, Fernanda, Agresta, Ferdinando, Cordera, Fernando, Pardo, Fernando, Mendoza-Moreno, Fernando, Munoz-Flores, Fernando, Silvestri, Francesca Maria, Tropeano, Francesca Paola, Pecchini, Francesca, Serio, Francesca, Colombo, Francesco, Di Marzo, Francesco, Ferrara, Francesco, Lancellotti, Francesco, Litta, Francesco, Martini, Francesco, Roscio, Francesco, Blanco-Antona, Francisco, Barcenas, Francisco Javier Quezada, Schlottmann, Francisco, Herrera-Almario, Gabriel, van Ramshorst, Gabrielle, Gallo, Gaetano, Luglio, Gaetano, Kampouroglou, Georgios, Papadopoulos, Georgios, Arredondo, Gerardo, Calini, Giacomo, Formisano, Giampaolo, Galiffa, Giampaolo, Palini, Gian Marco, Colucci, Gianluca, Pagano, Gianluca, Vanni, Gianluca, Pattacini, Gianmaria Casoni, Gravante, Gianpiero, Lisi, Giorgio, Bellanova, Giovanni, De Nobili, Giovanni, Necchi, Giovanni Sammy, Sinibaldi, Giovanni, Bacchiocchi, Giulia, Bagaglini, Giulia, Maggi, Giulia, Izzo, Giuliano, Argenio, Giulio, Brisinda, Giuseppe, Esposito, Giuseppe, Frazzetta, Giuseppe, De Luca, Giuseppe Massimiliano, Nigri, Giuseppe, Sica, Giuseppe, Martin-Martin, Gonzalo, Ugon, Gustavo Armand, Martinez-Mier, Gustavo, Machain Vega, Gustavo Miguel, Nari, Gustavo, Nikaj, Herald, Neri, Ignacio, San Roman, Igor Alberdi, Fidoshev, Iliya, Martínez, Iñaki, Negoi, Ionut, Ortega, Irene, Vicente Rodríguez, Irune, Cornejo, Isabel, Mora-Guzmán, Ismael, al-Najami, Issam, Romic, Ivan, Balciscueta, Izaskun, Olivier, James, Lammel-Lindemann, Jan, Dziakova, Jana, Salinas, Javier, Jovanovic, Jelena Pejanovic, Reyes, Jeryl Anne Silvia, Salas, Joanne, Diaz-Elizondo, Jose Antonio, Parreira, Jose Gustavo, Bellido, Juan, Salamea, Juan, Martín del Olmo, Juan Carlos, Ordoñez, Juliana María, Junaid, Sofi, Davies, Justin, Sahnan, Kapil, Bekele, Kebebe, Voon, Kelvin, Siragusa, Leandro, Petagna, Lorenzo, Ferrario, Luca, Giordano, Luca, Nespoli, Luca, Pio, Luca, Moletta, Lucia, Curella, Luciano, Taglietti, Lucio, Bonavina, Luigi, Conti, Luigi, Pérez-Sánchez, Luis Eduardo, Cabrera Vargas, Luis Felipe, Sánchez-Guillén, Luis, Tallon-Aguilar, Luis, Khan, Mansoor, Spampinato, Marcello Giuseppe, Viola, Marcelo, Malet, Marcelo Viola, Angrisani, Marco, Calussi, Marco, Catarci, Marco, Giordano, Marco, Materazzo, Marco, Milone, Marco, Pellicciaro, Marco, Marino, Marco Vito, Moreno Villamizar, María Daniela, Lolli, Maria Giulia, Bellini, Maria Irene, Lemma, Maria, Chiarello, Maria Michela, Montes-Manrique, Mario, Rodriguez-Lopez, Mario, Serradilla-Martín, Mario, Peter, Mark, Paniagua-García-Señoráns, Marta, Rutegård, Martin, Salö, Martin, Silveri, Massimiliano, Veroux, Massimiliano, Nardi, Matteo, Rottoli, Matteo, Tolonen, Matti, Pedraza Ciro, Mauricio, Zuluaga, Mauricio, Iacobone, Maurizio, Montuori, Mauro, Ali, Mazin, García Domínguez, Melody, Paola, Menna Maria, Piccoli, Micaela, Campanelli, Michela, De Rosa, Michele, Manigrasso, Michele, Maruccia, Michele, Torre, Michele, Zuolo, Michele, Pera, Miguel, Weerasekera, Mihiri, Prieto, Mikel, Thway, Min Myat, Shaat, Mohamed, Azfar, Mohammad, Shalaby, Mostafa, Raza, Muhammad Asif, Younis, Muhammad Umar, Elhadi, Muhammed, Ali, Mujahid, Althomali, Musab, Al Amri, Nadiah, Dudi-Venkata, Nagendra, Alselaim, Nahar, Smart, Neil, Trelles, Nelson, Falco, Nicolò, Petrucciani, Niccolo, Antonacci, Nicola, Cillara, Nicola, Gica, Nicolae, Pecorelli, Nicolò, Tamini, Nicolò, Machairas, Nikolaos, Feituri, Nura, Ortega Torrecilla, Nuria, Avila Mercado, Octavio, Alaamer, Ohood, Irkorucu, Oktay, Alsherif, Omar, Buonomi, Oreste Claudio, Valles-Guerra, Orestes, Ioannidis, Orestis, Hernández Palmas, Oscar Isaac, Sanz Guadarrama, Oscar, Bozbiyik, Osman, Rodrigues, Pablo, Milito, Pamela, Panaccio, Paolo, Dorovinis, Panagiotis, Prieto, Paola, Baroffio, Paolo, Marsanic, Patrizia, Ajawin, Pawel, Koh, Peng Soon, Anoldo, Pietro, Major, Piotr, Alharthi, Qasem, Lui, Rashid, Caruso, Riccardo, Brady, Richard, Rattan, Rishi, Singhal, Rishi, Angelico, Roberta, Isernia, Roberta Maria, Tutino, Roberta, Peltrini, Roberto, Tejos, Rodrigo, Fajardo, Roosevelt, Elia, Rossella, Morales-Conde, Salvador, Benli, Sami, Fuentes, Sara, de las Casas, Sara Gortázar, de Guzmán Aragón, Sara Ortiz, Vertaldi, Sara, Awad, Selmy, Gentilli, Sergio, Weckmann Lujan, Sergio Alberto, Tayar, Serkan, Althobaiti, Shabab, Di Giovanni, Silvia, Ghedan, Soliman, Pérez-Bertólez, Sonia, Chiappetta, Sonja, Delis, Spiros, Scaringi, Stefano, Çetinkünar, Süleyman, Kykalos, Stylianos, Muhammad Ali, Syed, Krivan, Sylvia, Fung, Tak Lit Derek, Delko, Tarik, Nicolás López, Tatiana, De Campos, Tercio, Calderón Duque, Teresa, Perra, Teresa, Liakakos, Theodore, Daskalakis, Theodoros, Koëter, Tijmen, Zalla, Tiku, González, Tomás Elosua, Campagnaro, Tommaso, Oumar, Toure Alpha, Grossi, Ugo, Sosa, Valentina, Testa, Valentina, Tomajer, Valentina, Andriola, Valeria, Tonini, Valeria, Celentano, Valerio, Voglino, Valerio, Katta, Venkateswara Rao, García Orozco, Víctor Hugo, Turrado-Rodriguez, Victor, Visag-Castillo, Victor, Graham, Victoria, Rachkov, Viktor, Papagni, Vincenzo, Vigorita, Vincenzo, Jiménez Carneros, Virginia, Bellato, Vittoria, Bechstein, Wolf, Altinel, Yuksel, Balciscueta, Zutoia, Pata, Francesco, Di Martino, Marcello, Podda, Mauro, Di Saverio, Salomone, Ielpo, Benedetto, Pellino, Gianluca, Luglio, Gaetano, Pata, F, Di Martino, M, Podda, M, Di Saverio, S, Ielpo, B, Pellino, G, Julio, A, Alshamrani, A, Alturkistani, A, Alghamdi, A, Almalki, A, Orengia, A, Kuvvetli, A, Pisanu, A, Smith, A, Trevino Figueroa, A, Nacion, A, Alhazmi, A, Bouhuwaish, A, Khalid, A, Alsufyani, A, Rubio, A, Bavikatte, A, Kumar, A, Jamiri, A, de San Ildefonso Pereira, A, Porcu, A, Sartori, A, Rocca, A, Sretenovic, A, Anselmo, A, De Luca, A, Charalabopoulos, A, Tzivanakis, A, Bandin, A, Najar, A, Frontali, A, Faisal, A, Roldan, A, Hamid, A, Andre, A, Minaya-Bravo, A, Das, A, Bondurri, A, Costanzi, A, Lucchi, A, Mihailescu, A, Police, A, Zuchini, A, Romano, A, Iossa, A, Chessa, A, Tromba, A, Castaldi, A, Brillantino, A, Ferronetti, A, Giuliani, A, Ramos-De la Medina, A, Tarasconi, A, Picciariello, A, Ioannidis, A, Leppaniemi, A, Rashid, A, Mitul, A, Mehraj, A, Laharwal, A, Iqbal, A, Liarakos, A, Marinis, A, de Andres-Asenjo, B, Matias-Garcia, B, De Simone, B, Creavin, B, Stubbs, B, Goh, B, Jovanovic, B, Sensi, B, Gazia, C, Cerdan, C, Diaz, C, Chacon, C, Yanez, C, Faro, C, Reinke, C, Dominguez, C, Paranjape, C, Thomas, C, Fung, C, De Lucia, C, Jennifer, C, Ovalle-Chao, C, Guerci, C, Kenington, C, Gica, C, Folliero, C, Varela, C, Popowich, D, Delogu, D, Zigiotto, D, Vinci, D, D'Antonio, D, Merlini, D, Moro-Valdezate, D, Keller, D, Nicolaescu, D, Sasia, D, Rodas, E, Linardoutsos, D, Russello, D, Najar-Castaneda, P, Stavrou, H, Rosso, E, Saladino, E, Ricciardi, E, Smith-Singares, E, Baili, E, Douka, E, Guaitoli, E, Francone, E, Vaterlini, E, Pierobon, E, Morales, E, Ros, E, Benzoni, E, Erdas, E, Pinotti, E, Colas-Ruiz, E, Laterza, E, Foianini, E, Cardamone, E, Licardie, E, Marino, F, Alsofyani, F, Qahtani, F, Khan, F, Maraska, F, Saliu, F, Madrid, F, Rosa, F, Luvisetto, F, Alconchel, F, Pareja-Ciuro, F, Neves, F, Agresta, F, Cordera, F, Pardo, F, Mendoza-Moreno, F, Munoz-Flores, F, Silvestri, F, Tropeano, F, Pecchini, F, Serio, F, Colombo, F, Di Marzo, F, Ferrara, F, Lancellotti, F, Litta, F, Martini, F, Roscio, F, Blanco-Antona, F, Barcenas, F, Schlottmann, F, Herrera-Almario, G, van Ramshorst, G, Gallo, G, Luglio, G, Kampouroglou, G, Papadopoulos, G, Arredondo, G, Calini, G, Formisano, G, Galiffa, G, Palini, G, Colucci, G, Pagano, G, Vanni, G, Pattacini, G, Gravante, G, Lisi, G, Bellanova, G, De Nobili, G, Necchi, G, Sinibaldi, G, Bacchiocchi, G, Bagaglini, G, Maggi, G, Izzo, G, Argenio, G, Brisinda, G, Esposito, G, Frazzetta, G, De Luca, G, Nigri, G, Sica, G, Martin-Martin, G, Ugon, G, Martinez-Mier, G, Machain Vega, G, Nari, G, Nikaj, H, Neri, I, San Roman, I, Fidoshev, I, Martinez, I, Negoi, I, Ortega, I, Vicente Rodriguez, I, Cornejo, I, Mora-Guzman, I, al-Najami, I, Romic, I, Balciscueta, I, Olivier, J, Lammel-Lindemann, J, Dziakova, J, Salinas, J, Jovanovic, J, Reyes, J, Salas, J, Diaz-Elizondo, J, Parreira, J, Bellido, J, Salamea, J, Martin del Olmo, J, Ordonez, J, Junaid, S, Davies, J, Sahnan, K, Bekele, K, Voon, K, Siragusa, L, Petagna, L, Ferrario, L, Giordano, L, Nespoli, L, Pio, L, Moletta, L, Curella, L, Taglietti, L, Bonavina, L, Conti, L, Perez-Sanchez, L, Cabrera Vargas, L, Sanchez-Guillen, L, Tallon-Aguilar, L, Khan, M, Spampinato, M, Viola, M, Malet, M, Angrisani, M, Calussi, M, Catarci, M, Giordano, M, Materazzo, M, Milone, M, Pellicciaro, M, Marino, M, Moreno Villamizar, M, Lolli, M, Bellini, M, Lemma, M, Chiarello, M, Montes-Manrique, M, Rodriguez-Lopez, M, Serradilla-Martin, M, Peter, M, Paniagua-Garcia-Senorans, M, Rutegard, M, Salo, M, Silveri, M, Veroux, M, Nardi, M, Rottoli, M, Tolonen, M, Pedraza Ciro, M, Zuluaga, M, Iacobone, M, Montuori, M, Ali, M, Garcia Dominguez, M, Paola, M, Piccoli, M, Campanelli, M, De Rosa, M, Manigrasso, M, Maruccia, M, Torre, M, Zuolo, M, Pera, M, Weerasekera, M, Prieto, M, Thway, M, Shaat, M, Azfar, M, Shalaby, M, Raza, M, Younis, M, Elhadi, M, Althomali, M, Al Amri, N, Dudi-Venkata, N, Alselaim, N, Smart, N, Trelles, N, Falco, N, Petrucciani, N, Antonacci, N, Cillara, N, Gica, N, Pecorelli, N, Tamini, N, Machairas, N, Feituri, N, Ortega Torrecilla, N, Avila Mercado, O, Alaamer, O, Irkorucu, O, Alsherif, O, Buonomi, O, Valles-Guerra, O, Ioannidis, O, Hernandez Palmas, O, Sanz Guadarrama, O, Bozbiyik, O, Rodrigues, P, Milito, P, Panaccio, P, Dorovinis, P, Prieto, P, Baroffio, P, Marsanic, P, Ajawin, P, Koh, P, Anoldo, P, Major, P, Alharthi, Q, Lui, R, Caruso, R, Brady, R, Rattan, R, Singhal, R, Angelico, R, Isernia, R, Tutino, R, Peltrini, R, Tejos, R, Fajardo, R, Elia, R, Morales-Conde, S, Benli, S, Fuentes, S, de las Casas, S, de Guzman Aragon, S, Vertaldi, S, Awad, S, Gentilli, S, Weckmann Lujan, S, Tayar, S, Althobaiti, S, Di Giovanni, S, Ghedan, S, Perez-Bertolez, S, Chiappetta, S, Delis, S, Scaringi, S, Cetinkunar, S, Kykalos, S, Muhammad Ali, S, Krivan, S, Fung, T, Delko, T, Nicolas Lopez, T, De Campos, T, Calderon Duque, T, Perra, T, Liakakos, T, Daskalakis, T, Koeter, T, Zalla, T, Gonzalez, T, Campagnaro, T, Oumar, T, Grossi, U, Sosa, V, Testa, V, Tomajer, V, Andriola, V, Tonini, V, Celentano, V, Voglino, V, Katta, V, Garcia Orozco, V, Turrado-Rodriguez, V, Visag-Castillo, V, Graham, V, Rachkov, V, Papagni, V, Vigorita, V, Jimenez Carneros, V, Bellato, V, Bechstein, W, Altinel, Y, Balciscueta, Z, Institut Català de la Salut, [Pata F] General Surgery Unit, UOC di Chirurgia, Nicola Giannettasio Hospital, CS, Italy. La Sapienza University, Rome, Italy. [Di Martino M] Division of Hepatobiliary and Liver Transplantation Surgery, A.O.R.N. Cardarelli, Naples, Italy. [Podda M] Department of Surgical Science, University of Cagliari, Cagliari, Italy. [Di Saverio S] Department of Surgery, Madonna del Soccorso General Hospital, San Benedetto del Tronto, Italy. [Ielpo B] Hepatobiliary division, Hospital del Mar, Universitat Pompeu Fabra, Barcelona, Spain. [Pellino G] Department of Advanced Medical and Surgical Sciences, Universitá degli Studi della Campania ‘‘Luigi Vanvitelli’’, Policlinico CS, Naples, Italy. Unitat de Cirurgia de Còlon i Recte, Vall d’Hebron Hospital Universitari, Barcelona, Spain, and Vall d'Hebron Barcelona Hospital Campus
- Subjects
Investigative Techniques::Epidemiologic Methods::Data Collection::Surveys and Questionnaires [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT] ,covid-19, surgery ,coronavirus ,sars-cov-2 ,appendicectomy ,laparoscopy ,nom ,management ,Enquestes ,Apendicectomia ,COVID-19 (Malaltia) ,surgery ,Surgical Procedures, Operative::Digestive System Surgical Procedures::Appendectomy [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT] ,Apendicitis ,Pandèmia de COVID-19, 2020 ,Appendectomy ,Humans ,Appendiciti ,Pandemics ,Cirurgia ,Pandemic ,SARS-CoV-2 ,COVID-19 ,Digestive System Diseases::Gastrointestinal Diseases::Gastroenteritis::Digestive System Diseases::Gastrointestinal Diseases::Appendicitis [DISEASES] ,Otros calificadores::Otros calificadores::/cirugía [Otros calificadores] ,técnicas de investigación::métodos epidemiológicos::recopilación de datos::encuestas y cuestionarios [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS] ,Appendicitis ,Apendicitis - Cirurgia ,Other subheadings::Other subheadings::/surgery [Other subheadings] ,Settore MED/18 ,Settore MED/18 - Chirurgia Generale ,Acute Disease ,enfermedades del sistema digestivo::enfermedades gastrointestinales::gastroenteritis::enfermedades del sistema digestivo::enfermedades gastrointestinales::apendicitis [ENFERMEDADES] ,intervenciones quirúrgicas::procedimientos quirúrgicos del sistema digestivo::apendicectomía [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS] ,Human - Abstract
Background In 2020, ACIE Appy study showed that COVID-19 pandemic heavily affected the management of patients with acute appendicitis (AA) worldwide, with an increased rate of non-operative management (NOM) strategies and a trend toward open surgery due to concern of virus transmission by laparoscopy and controversial recommendations on this issue. The aim of this study was to survey again the same group of surgeons to assess if any difference in management attitudes of AA had occurred in the later stages of the outbreak. Methods From August 15 to September 30, 2021, an online questionnaire was sent to all 709 participants of the ACIE Appy study. The questionnaire included questions on personal protective equipment (PPE), local policies and screening for SARS-CoV-2 infection, NOM, surgical approach and disease presentations in 2021. The results were compared with the results from the previous study. Results A total of 476 answers were collected (response rate 67.1%). Screening policies were significatively improved with most patients screened regardless of symptoms (89.5% vs. 37.4%) with PCR and antigenic test as the preferred test (74.1% vs. 26.3%). More patients tested positive before surgery and commercial systems were the preferred ones to filter smoke plumes during laparoscopy. Laparoscopic appendicectomy was the first option in the treatment of AA, with a declined use of NOM. Conclusion Management of AA has improved in the last waves of pandemic. Increased evidence regarding SARS-COV-2 infection along with a timely healthcare systems response has been translated into tailored attitudes and a better care for patients with AA worldwide.
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- 2022
16. Prenatal features of mandibulofacial dysostosis Guion-Almeida Type
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Dragoi, Vlad, Nedelea, Florina, Gica, Nicolae, Botezatu, Radu, Peltecu, Gheorghe, and Panaitescu, Anca Maria
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Guion-Almeida ,prenatal ultrasound ,mandibulofacial dysostosis ,Case Report ,General Medicine ,whole exome sequencing - Abstract
Facial dysostoses are clinically and genetically heterogeneous conditions characterized by congenital craniofacial anomalies which result from abnormal development of the first two pharyngeal arches and their derivatives during embryogenesis. Mandibulofacial dysostosis Guion-Almeida type (MFDGA) is a rare and relatively new syndrome described in the literature, first identified by Guion-Almeida et al. in 2000 and 2006. Another 108 cases have been documented after that. Prenatal diagnosis of this syndrome has not been described yet. Here we present the prenatal ultrasound findings in a case where MFDGA was confirmed after delivery. We suggest that MFDGA should be included in the prenatal differential diagnosis of syndromes with micrognathia and craniofacial anomalies.
- Published
- 2021
17. Risk of Subsequent Hysterectomy after Expectant Management in the Treatment of Placenta Accreta Spectrum Disorders
- Author
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Panaitescu, Anca Maria, primary, Peltecu, Gheorghe, additional, Botezatu, Radu, additional, Iancu, George, additional, and Gica, Nicolae, additional
- Published
- 2022
- Full Text
- View/download PDF
18. Review of: "Comparative Study between Using Only Vaginal Misoprostol and Using Vaginal Misoprostol and Estradiol Cream for Induction of Labour: Randomized controlled trial"
- Author
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Gica, Nicolae, primary
- Published
- 2022
- Full Text
- View/download PDF
19. Risk of vertical transmission of chronic viral infections after invasive prenatal procedures
- Author
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Cimpoca, Brindusa, primary, Panaitescu, Anca Maria, additional, Gica, Nicolae, additional, Veduta, Alina, additional, and Ciobanu, Anca, additional
- Published
- 2022
- Full Text
- View/download PDF
20. Recurrent Congenital Heart Block Due to Maternal Anti-Ro Antibodies: Successful Prevention of Poor Pregnancy Outcome with Hydroxychloroquine and Added Dexamethasone
- Author
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Cimpoca-Raptis, Brindusa, primary, Ciobanu, Anca Marina, additional, Gica, Nicolae, additional, Scutelnicu, Ana Maria, additional, Bouariu, Alexandra, additional, Popescu, Mihaela, additional, and Panaitescu, Anca Maria, additional
- Published
- 2022
- Full Text
- View/download PDF
21. Prognosis and Management in Subsequent Rh Alloimmunized Pregnancies
- Author
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DUMITRU, Andreea, GICA, Nicolae, BOTEZATU, Radu, and PELTECU, Gheorghe
- Subjects
Review - Abstract
Background: RhD alloimmunization remains a severe problem worldwide, but its management has been revolutionized by two important discoveries: the possibility to establish fetal Rh genotype non-invasively by using a maternal blood sample, and using of Doppler velocimetry to monitor early signs of affected fetuses. Materials and methods: We performed a literature review by searching PubMed for relevant information about diagnosis, prognosis, and management of secondary affected Rh alloimmunized pregnancies. Results:The risk to develop fetal anemia and hydrops seems to increase with increasing concentrations of Rh antibodies, and studies show it is higher for subsequent pregnancies. Individuals presenting the DEL phenotype with the types 1, 2 or 3 can be considered RhD positive and anti-D immune globulin is not indicated. Discussions: Medical algorithm involves previous pregnancy history together with serum parameters. Follow-up in a department of maternal fetal medicine is desired and encouraged in these cases. Depending on the severity and woman’s previous pregnancy history, especially condition prior to 24 weeks of gestation, several therapies such as plasmaphereses, intravenous immune globulin or intrauterine transfusions can be conducted. Intrauterine transfusions have a better prognosis when performed earlier and on fetuses without hydrops. Conclusion:Although the incidence of hemolytic disease of the fetus and newborn has decreased and is no longer a major cause of perinatal mortality, vigilance is still required. There is a strong argument for reunite the management of these cases in dedicated maternal fetal medicine centers that perform invasive procedures in order to improve knowledge, gain skills and enhance clinical management.
- Published
- 2021
22. Platelet Changes in Pregnancies with Severe Early Fetal Intrauterine Growth Restriction
- Author
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Ciobanu, Anca Marina, primary, Panaitescu, Anca Maria, additional, Gica, Nicolae, additional, Scutelnicu, Ana Maria, additional, Bouariu, Alexandra, additional, and Popescu, Mihaela Roxana, additional
- Published
- 2021
- Full Text
- View/download PDF
23. Pregnancy Complications Can Foreshadow Future Disease—Long-Term Outcomes of a Complicated Pregnancy
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Panaitescu, Anca Maria, primary, Popescu, Mihaela Roxana, additional, Ciobanu, Anca Marina, additional, Gica, Nicolae, additional, and Cimpoca-Raptis, Brindusa Ana, additional
- Published
- 2021
- Full Text
- View/download PDF
24. Fetal Surveillance in Pregnancies with Myasthenia Gravis
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Cimpoca-Raptis, Brîndușa Ana, primary, Ciobanu, Anca Marina, additional, Gica, Nicolae, additional, Peltecu, Gheorghe, additional, Mitrea, Dan, additional, and Panaitescu, Anca Maria, additional
- Published
- 2021
- Full Text
- View/download PDF
25. Absence of Wharton’s Jelly at the Abdominal Site of the Umbilical Cord Insertion. Rare Case Report and Review of the Literature
- Author
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Botezatu, Radu, primary, Raduteanu, Sandra, additional, Ciobanu, Anca Marina, additional, Gica, Nicolae, additional, Peltecu, Gheorghe, additional, and Panaitescu, Anca Maria, additional
- Published
- 2021
- Full Text
- View/download PDF
26. Rosai–Dorfman Disease: Breast Involvement—Case Report and Literature Review
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Iancu, George, primary, Gica, Nicolae, additional, Mustata, Laura Mihaela, additional, Panaitescu, Anca Maria, additional, Vasile, Danut, additional, and Peltecu, Gheorghe, additional
- Published
- 2021
- Full Text
- View/download PDF
27. Ultrasound Patterns in the First Trimester Diagnosis of Congenital Heart Disease
- Author
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Herghelegiu, Catalin G., primary, Panaitescu, Anca Maria, additional, Duta, Simona, additional, Vayna, Ana Maria, additional, Ciobanu, Anca Marina, additional, Bulescu, Cristian, additional, Ioan, Raluca Gabriela, additional, Neacsu, Adrian, additional, Gica, Nicolae, additional, and Veduta, Alina, additional
- Published
- 2021
- Full Text
- View/download PDF
28. Myelomeningocele Surgery over the 10 Years Following the MOMS Trial: A Systematic Review of Outcomes in Prenatal versus Postnatal Surgical Repair
- Author
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Paslaru, Francesca Gabriela, primary, Panaitescu, Anca Maria, additional, Iancu, George, additional, Veduta, Alina, additional, Gica, Nicolae, additional, Paslaru, Alexandru Catalin, additional, Gheorghiu, Anamaria, additional, Peltecu, Gheorghe, additional, and Gorgan, Radu Mircea, additional
- Published
- 2021
- Full Text
- View/download PDF
29. Double Ovarian Stimulation in the Same Ovarian Cycle
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GICA, Corina, MAXIM, Bogdan-Gabriel, BOTEZATU, Radu, PELTECU, Gheorghe, PANAITESCU, Anca Maria, IORDACHESCU, Diana, and GICA, Nicolae
- Subjects
Review - Abstract
The theory of multicyclic development of follicles during the menstrual cycle prompted new approaches to ovarian stimulation such as double stimulation within the same menstrual cycle, in both follicular and luteal phases. New stimulation approaches, together with cryopreservation techniques, provide higher chances for patients with poor ovarian response who undergo in vitro fertilization (IVF) to get pregnant. The double ovarian stimulation protocol has been proposed to optimize the number of oocytes retrieved within the shortest possible timeframe. Moreover, the short overall duration of this strategy is also useful in cases of a fertility preservation that requires rapid intervention before administering a gonadotoxic therapy, such as in oncologic therapy. In general, the aim of DUOSTIM is to obtain the highest number of oocytes in the shortest time, thus avoiding waste of time, which is crucial for these patients. Several protocols have been proposed with similar results, regardless of the protocol used.
- Published
- 2021
30. Asthma in Pregnancy. Review of Current Literature and Recommendations
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POPA, Maria, PELTECU, Gheorghe, GICA, Nicolae, CIOBANU, Anca Marina, BOTEZATU, Radu, GICA, Corina, STERIADE, Alexandru, and PANAITESCU, Anca Maria
- Subjects
Review - Abstract
Background:Asthma is the most common respiratory disorder affecting women during pregnancy. Although it is a reversible disease, it may adversely affect maternal quality of life and perinatal outcomes, especially in severe and inappropriately managed cases. Conversely, pregnancy influences the course of asthma through the physiological respiratory, hormonal, and immune system changes. Exacerbations are a key feature of asthma, representing a significant problem if severe, requiring aggressive medical intervention, hospital and even ICU admission. Purpose: The purpose of this article is to summarize the current knowledge and to provide a comprehensive overview of asthma in pregnancy. We also want rising awareness among patients and clinicians on the importance of proper asthma management during pregnancy. Data sources: A comprehensive literature search in PubMed, Medline, and Taylor& Francis was performed. We have searched for review articles as well as prospective and retrospective studies published in English, investigating the bilateral relationship between asthma and pregnancy, using the key words mentioned bellow. Manual search through both national and international guidelines as well as relevant journals and publications on the topic has been also conducted. Conclusion:Optimal asthma control, preventing, detecting, and treating the exacerbations are of the utmost importance to minimize the adverse effects for both the mother and fetus/neonate. Guidelines recommend active asthma management during pregnancy. Strong support prior and throughout the pregnancy and individualized treatment, guided by a multidisciplinary team, is suggested. Education on the importance of anti-asthmatic therapy, avoiding triggers, frequent and accurate monitoring are essential for good asthma management. Considering the pandemic, we are facing and the potential impact of COVID-19 on asthma, Global Initiative for Asthma (GINA) guideline recommendations for physicians are mentioned in the present article.
- Published
- 2021
31. Corpus luteum in ectopic ovarian tissue miming tubal pregnancy
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Darii Plopa, Natalia, primary, Gica, Nicolae, additional, Gica, Corina, additional, and Anton, Emil, additional
- Published
- 2021
- Full Text
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32. The social and the psychological impact of endometriosis on the Romanian urban population
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Baciu, Iulia, primary, Irimie-Ana, Alecsandra, additional, Panaitescu, Anca, additional, Peltecu, Gheorghe, additional, Gica, Corina, additional, and Gica, Nicolae, additional
- Published
- 2021
- Full Text
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33. Screening for Gestational Diabetes during the COVID-19 Pandemic—Current Recommendations and Their Consequences
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Panaitescu, Anca Maria, primary, Ciobanu, Anca Marina, additional, Popa, Maria, additional, Duta, Irina, additional, Gica, Nicolae, additional, Peltecu, Gheorghe, additional, and Veduta, Alina, additional
- Published
- 2021
- Full Text
- View/download PDF
34. Antiviral medication to prevent fetal transmission of maternal CMV during pregnancy.
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Birsanu, Simona, Gica, Nicolae, Botezatu, Radu, Peltecu, Gheorghe, and Panaitescu, Anca Maria
- Subjects
- *
CYTOMEGALOVIRUS diseases , *CONGENITAL disorders , *VIRUS diseases , *DRUGS , *CENTRAL nervous system - Abstract
Background. Cytomegalovirus infection represents the most frequent congenital viral infection, with serious consequences on newborns. Neurosensorial hearing loss is the principal outcome, but also, the infection can cause other central nervous system’s anomalies. Although CMV infection can have a major impact on fetal development, there are not clear directions to follow yet, to prevent or treat this condition. Therefore, our purpose with this paper is to update the knowledge regarding the treatment options in order to prevent fetal transmission of maternal CMV infection, based on the latest data from the specialized literature in this field. Methods. Electronic research and analysis of the relevant articles published mainly in the last 5 years were performed, consulting the web platforms PubMed, ScienceDirect, Mendeley and ClinicalTrials.gov. Results and conclusions. To date, there is not enough evidence to reach a consensus on therapeutic methods to prevent or to treat fetal CMV infections and, as a consequence, antenatal screening is not justified. Many pharmaceutical companies work on vaccines to prevent CMV infection, but the results are only from studies’ second phase. Information on efficiency of hyperimmunoglobulin is mixt and it is necessary to clarify the dosage. Among antiviral agents, valaciclovir, which was studied in recent clinical trials, seems to have the best efficiency to prevent fetal transmission of maternal CMV infection and the best safety profile. Valganciclovir has possible embryotoxic effects, but higher potency and information on it are available only from case reports. The interest of scientific community on this topic is high, thus many studies are underway to bring new clarifications. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
35. Ultrasound Appearance of Fetal Posterior Fossa and a Case Report of Prenatal Diagnosis of Dandy-Walker Malformation.
- Author
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GICA, Nicolae, PANAITESCU, Anca Maria, GICA, Corina, DUMITRU, Andreea, BOTEZATU, Radu, PELTECU, Gheorghe, and VAYNA, Ana Maria
- Subjects
- *
FETAL ultrasonic imaging , *POSTERIOR cranial fossa , *PRENATAL diagnosis , *HUMAN abnormalities , *CENTRAL nervous system , *SPINA bifida - Abstract
Prenatal sonographic assessment of the posterior fossa in the mid-sagittal plane at 11-14 weeks' gestation has been highlighted as an essential diagnostic step by the current literature. This approach is used for the early detection of open spina bifida during the first trimester by analyzing the three spaces of the posterior fossa: brain stem, the fourth ventricle and cisterna magna. Abnormal size of fetal posterior fossa spaces is an important sign in the diagnosis of fetuses with central nervous system malformation and needs to be submitted for differential diagnosis when any alterations are observed. Among them, Dandy-Walker malformation is one of the major causes of congenital hydrocephalus, being a rare condition, with poor-prognosis, manifested by enlarged posterior fossa. On the basis of available evidence, the assessment of the fetal posterior cranial fossa is feasible from 11 to 14 weeks gestational age and it is believed that abnormal appearance of the posterior fossa at this stage of pregnancy could improve early detection of Dandy-Walker malformation by prompting an early second trimester ultrasound evaluation. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
36. Anesthesia during pregnancy.
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Negoita, Silvius, Gica, Nicolae, Ciobanu, Anca Marina, Peltecu, Gheorghe, and Panaitescu, Anca Maria
- Subjects
- *
CESAREAN section , *PREGNANCY , *PREGNANT women , *ANESTHESIA , *OPERATIVE surgery , *GESTATIONAL age - Abstract
Surgery during pregnancy post additional concerns an represent a major stress factor for both anesthesiologist and gynecologists. Approximately 0.5-2% of all pregnant women undergo a least one nonobstetric surgery during their pregnancy, and the number is growing in recent years. Until present days, no anesthetic drug has been shown to be clearly dangerous to human fetus. Thus, a pregnant woman should never be delayed from surgery regardless of teratogenic effects at any gestational age. The choice of anesthetic technique, drugs and surgical procedure should be guided by mother safety and continuation of adequate uteroplacental perfusion. Regarding Cesarean Section, it is now the most common surgery performed in the United States, with over 1 million women delivered by cesarean every year. Due to medical and legal implication, anesthesia must be safe in order to improve maternal and fetal outcome. Ultimately, success of each case is granted by multidisciplinary team approach and adherence to the latest clinical practice guidelines. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
37. Trauma in pregnancy.
- Author
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Atanasescu, Ioana Emanuela, Gica, Nicolae, Botezatu, Radu, Ciobanu, Anca, Peltecu, Gheorghe, and Panaitescu, Anca Maria
- Subjects
- *
CESAREAN section , *MISCARRIAGE , *ABRUPTIO placentae , *PREGNANCY , *BLOOD cell count , *RH factor - Abstract
Trauma is complicating 1 in 12 pregnancy and is considered to be the first cause of non-obstetrical maternal death. Frequently encountered complications are preterm delivery, placental abruption or spontaneous abortion. Presence of the gravid uterus is a major contributor that increases the risk of the occurrence of possible wounds, and as the pregnancy progresses, multiple changes that occur can make the management of the pregnant patient harder. Studies have shown that domestic abuse should not be overlooked. First evaluation needed for pregnant trauma woman comprise complete blood count, coagulation profile, Rh factor determination, urine analysis, electrolytes and glucose, toxicology screening and the Kleinhauer-Betke (KB) test. Also, diagnostic imaging is not discouraged, and may raise and also confirm the suspicion for placental abruption or uterine rupture. In case of cardiac arrest and unsuccessful resuscitation of the mother within 4 minutes, literature recommends a perimortem cesarean delivery, if gestational age is above 23 weeks and the fetus is potentially viable. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
38. Hemolytic disease of the newborn, beyond the Rhesus disease.
- Author
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Huszti, Ana Maria, Gica, Nicolae, Botezatu, Radu, Peltecu, Gheorghe, and Panaitescu, Anca Maria
- Subjects
- *
ERYTHROBLASTOSIS fetalis , *CORD blood , *DIAGNOSIS , *DISEASE management , *FETAL monitoring , *ERYTHROCYTES , *PRENATAL diagnosis - Abstract
Hemolytic disease of the fetus and newborn is a consequence of maternal immune response to fetal red blood cells antigens inherited from the father, that the mother does not possess, stimulated by antepartum or intrapartum fetomaternal hemorrhage. As a result, fetal erythrocytes are destroyed, leading to various degrees of anemia and hyperbilirubinemia, with high perinatal morbidity and mortality rates. This review's purpose is to reveal the importance of the alloantibodies beyond RhD and ABO system, the updated algorithms used in the diagnosis and management of the disease and the importance of RhD universal immune prophylaxis practice. For this purpose, the database from PubMed and UpToDate was searched for literature reviews, case studies, society guidelines and retrospective studies in English regarding hemolytic disease of the fetus and newborn from 2013 to March 2022. Anti D prophylaxis protocols, early diagnosis and proper intrauterine and postpartum treatment help significantly reduce the disease's burden. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
39. Behcet’s disease with oral manifestations during pregnancy.
- Author
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Ciocarlan, Maria, Gica, Nicolae, Botezatu, Radu, Peltecu, Gheorghe, and Panaitescu, Anca Maria
- Subjects
- *
ORAL manifestations of general diseases , *BEHCET'S disease , *ORAL diseases , *PREGNANCY , *MOUTH ulcers , *DISEASE exacerbation - Abstract
Behçet’s disease is a multisystemic inflammatory chronic vasculitis of unknown etiology characterized by recurrent oral ulcers, genital ulcers, eye lesions, and dermatological manifestations that is usually diagnosed during the reproductive years. There is limited information about the effects of Behçet’s disease on pregnancy and vice versa, but in most women, it appears to improve during this period. However, cases of activation or exacerbation of the disease in pregnancy are not uncommon and they are mainly manifested by oral ulcers, genital ulcers, and skin lesions. Corticosteroids and topical sucralfate are safe to use in pregnancy and while breastfeeding to treat oral ulcerations. The purpose of this study is to synthesize available information about Behçet’s disease oral manifestations in pregnancy, diagnosis, and treatment. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
40. Fetal cardiofibroelastosis - a consequence of anti-Ro maternal transfer during pregnancy. Case report and review of the literature.
- Author
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Turcu, Ana Duminica, Gica, Nicolae, Botezatu, Radu, Peltecu, Gheorghe, and Panaitescu, Anca Maria
- Subjects
- *
HEART block , *MEDICAL personnel , *SJOGREN'S syndrome , *OBSTETRICS , *PREGNANCY , *LITERATURE reviews - Abstract
With scarcely any reports published on the association of fetal endocardial fibroelastosis and Ro antibodies maternal transfer during pregnancy, this subject continues to raise concern among health care providers around the world, especially when neonatal lupus syndrome is taken into consideration as the main diagnosis. Fetuses with congenital atrioventricular block have a risk of intrauterine fetal demise and the concern comes from a variety of factors that show significant association between the presence of maternal antibodies to SS-A/Ro during pregnancy and their children serum level of these antibodies. Nevertheless, fetal endocardial fibroelastosis plays an important role in altering ventricular diastolic function and ventricular development in children and neonates. Methods. Medical literature was searched on PubMed and Medline using key words such as fetal endocardial fibroelastosis, anti-Ro antibodies in pregnancy and neonatal lupus syndrome and over 200 articles were taken into consideration, with 17 of them included in the final review. The clinical case included in this paper was referred to the Department of Maternal Fetal Medicine, Filantropia Clinical Hospital in Bucharest, during the second pregnancy after a first pregnancy that resulted in stillbirth with congenital heart block and fibroelastosis as a result of the maternal diagnosis of Sjogren’s syndrome with transplacental transfer of SS-A/Ro antibodies. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
41. Novel biomarkers in the differential diagnosis of preeclampsia and lupus flare in pregnancy.
- Author
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Ilie, Ilinca, Gica, Nicolae, Botezatu, Radu, Peltecu, Gheorghe, and Panaitescu, Anca Maria
- Subjects
- *
PREECLAMPSIA , *LUPUS nephritis , *PREGNANCY complications , *PREGNANCY , *SYSTEMIC lupus erythematosus , *DIFFERENTIAL diagnosis - Abstract
Preeclampsia and systemic lupus erythematosus are medical conditions with established elevated risks of pregnancy complications and fetal compromise. Active lupus during pregnancy can trigger the appearance of preeclampsia. Research has demonstrated an increase in lupus disease flares during pregnancy, secondary to hormonal shifts required in order to maintain pregnancy. Hemolytic anemia, leucopenia, thrombocytopenia, sudden onset of hypertension after 20 weeks of gestation and decreasing complement components such as C3, C4 and CH50 are hallmarks of lupus flares during pregnancy. Timely and accurate prediction of preeclampsia is now feasible through estimation of novel placental and endothelial biomarkers, chiefly sFlt-1 and PIGF. A sFlt-1 to PIGF ratio under 38, in patients under 34 weeks of gestation suspected of disease, boasts the highest negative predictive value for preeclampsia and can successfully rule out preeclampsia development in the following 4 weeks in patients with normal values. Moreover, the sFlt-1 to PIGF ratio has proven its utility in the differential diagnosis of preeclampsia and active lupus nephritis, with normal ratio values noted in cases of lupus flares during pregnancy. Further research is required in order to identify other novel potential biomarkers. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
42. Multiple sclerosis in pregnancy. Treatment options and outcomes: a review.
- Author
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Cudalba, Delia, Gica, Nicolae, Peltecu, Gheorghe, Botezatu, Radu, and Panaitescu, Anca Maria
- Subjects
- *
MULTIPLE pregnancy , *MULTIPLE sclerosis , *PREGNANCY outcomes , *TREATMENT effectiveness , *CHILDBEARING age - Abstract
Background. Women are commonly diagnosed with multiple sclerosis during reproductive age. There is need for disease control management during pregnancy, taking into consideration potential maternal and fetal risks. This review article aims to summarize what is acknowledged so far regarding treatment options of multiple sclerosis and outcomes in pregnancy, providing up-to-date information. Methods. In order to write this review a comprehensive literature electronic search for journal articles and guidelines regarding multiple sclerosis during pregnancy was undertaken. Results and conclusion. Multiple sclerosis management in pregnancy is a challenging issue. The use of disease-modifying drugs has improved both the course of the disease and the attitude towards pregnancy in patients living with multiple sclerosis. Pregnancy appears to have a protective effect on disease activity, particularly during the third trimester. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
43. Migraine and pregnancy.
- Author
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Dumitru, Andreea Elena, Gica, Nicolae, Botezatu, Radu, Peltecu, Gheorghe, and Panaitescu, Anca Maria
- Subjects
- *
MIGRAINE , *MORNING sickness , *PREGNANCY , *CHILDBEARING age , *NEUROLOGICAL disorders - Abstract
Background. Migraine is a frequent neurological disorder affecting mostly women in the childbearing age. It is influenced by fluctuation of female hormones, especially estrogen levels. Objectives. This review aims to describe the expression of migraine during the reproductive ages summarizing the diagnosis and effective, available treatment options. Materials and methods. We performed a systematic literature review searching information on the subject in PubMed and Medscape databases between 2000-2022. Outcomes. It reveals that during the first trimester due to symptoms of hyperemesis gravidarum, migraine attacks can exacerbate, while, through second and third trimester when estrogen levels rise, women report relief of symptoms. Therapy includes firstly behavioural approach and secondly pharmacological drugs along with non-invasive procedures, some still under investigation for pregnant state. For mild cases the first line is acetaminophen alone or together with antiemetics and in more severe cases or in women with past history of migraine triptans can used as the mainstay therapy. Conclusions. Despite recent discoveries on therapy and drugs, our understanding of the way medications may affect the fetus or new-born is incomplete and further evidence is needed, bringing potential for improved management of migraine during pregnancy [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
44. Neonatal and fetal alloimmune thrombocytopenia.
- Author
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ATANASESCU, Ioana Emanuela, GICA, Nicolae, BOTEZATU, Radu, PELTECU, Gheorghe, and PANAITESCU, Anca Maria
- Subjects
- *
THROMBOCYTOPENIA , *INTRACRANIAL hemorrhage , *INTRAVENOUS therapy , *SOCIAL interaction , *IMMUNE response - Abstract
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is the result of maternal alloantibodies interaction with human platelets antigen. Maternal alloantibodies are generated following the contact of maternal immune system with paternally acquired antigens on the fetal human platelets (PLTs). HPA-1a alloantibodies are responsible for more than 80% of cases of FNAIT. Low prevalence of FNAIT that occurs in less than 1 case out of 1000 births, and even a lower risk for intracranial hemorrhage makes a controversial discussion whether a screening in pregnant patients would bring benefits. Concerning pathogenesis of FNAIT, it has been shown that fetal platelets caring HPA-1a antigen enters maternal circulation and produce an immune response, that leads to production of HPA-1a maternal antibodies that afterwards can pass the placenta causing fetal thrombocytopenia. The majority of mothers who gave birth to a newborn with FNAIT usually are asymptomatic, although they might have a previous affected pregnancy. Although management of pregnancies complicated by FNAIT is still in discuss and controversial, a systemic review studies in 2017 showed that best guidance and delivery for pregnancies that are at risk for FNAIT is a weekly maternal administration of intravenous immunoglobulin, adding glucocorticoids depending on severity of FNAIT. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
45. Emotional disorders, marital adaptation and the moderating role of social support for couples under treatment for infertility
- Author
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Iordachescu, Diana Antonia, primary, Gica, Corina, additional, Vladislav, Elena Otilia, additional, Panaitescu, Anca Maria, additional, Peltecu, Gheorghe, additional, Furtuna, Mirona Elena, additional, and Gica, Nicolae, additional
- Published
- 2021
- Full Text
- View/download PDF
46. A Broader Perspective on the Prenatal Diagnosis of Cornelia de Lange Syndrome: Review of the Literature and Case Presentation
- Author
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Panaitescu, Anca Maria, primary, Duta, Simona, additional, Gica, Nicolae, additional, Botezatu, Radu, additional, Nedelea, Florina, additional, Peltecu, Gheorghe, additional, and Veduta, Alina, additional
- Published
- 2021
- Full Text
- View/download PDF
47. Counseling Process in Ductal Carcinoma In Situ
- Author
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Peltecu, Gheorghe, primary, Gica, Nicolae, primary, and Panaitescu, Anca Maria, primary
- Published
- 2021
- Full Text
- View/download PDF
48. Sentinel Lymph Node Biopsy in Breast Cancer. Principle, Difficulties and Pitfalls
- Author
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Iancu, George, primary, Mustata, Laura M., primary, Cigaran, Ruxandra, primary, Gica, Nicolae, primary, Botezatu, Radu, primary, Median, Dragos, primary, Panaitescu, Anca Maria, primary, and Peltecu, Gheorghe, primary
- Published
- 2021
- Full Text
- View/download PDF
49. Follow-up after Ductal Carcinoma In Situ Treatment
- Author
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Gica, Nicolae, primary, Mustata, Laura Mihaela, primary, Peltecu, Gheorghe, primary, and Panaitescu, Anca Maria, primary
- Published
- 2021
- Full Text
- View/download PDF
50. Menstrual cycle abnormalities in women vaccinated against COVID-19.
- Author
-
Zechiu, Ioana, Gica, Nicolae, Botezatu, Radu, Peltecu, Gheorghe, and Panaitescu, Anca Maria
- Subjects
- *
MENSTRUAL cycle , *WOMEN'S cycling , *VACCINATION , *COVID-19 , *METRORRHAGIA - Abstract
As more reports of menstrual cycle abnormalities after COVID-19 vaccine inoculation are emerging in media and in clinical practice as well, it was deemed necessary to investigate these claims. This review aims to gather current scientific evidence on COVID vaccination’s effect on menstrual cycle. Further and extensive research is undeniably needed to fully understand these phenomena, but current studies have demonstrated an undeniable link between some menstrual cycle abnormalities (especially heavy menstrual flow and variations in cycle length) and breakthrough bleeding in nonmenstruating population and vaccination against SARS-CoV-2. Up to this point, these disturbances seem to be temporary, not lasting for more than a few cycles. The reported menstrual changes have appeared after inoculations of all brands of vaccines, and no particular technology (mRNA or adenovirus-vectored) was particularly associated with them. The greatest concerns raised were those regarding fertility. However, until now, there is no evidence of any of the COVID vaccines affecting fertility when comparing vaccinated and unvaccinated populations. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
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